Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch |
Upregulated in class | absentNotch |
GeneSet | ET743_SARCOMA_72HRS_DN |
Enrichment Score (ES) | -0.6007696 |
Normalized Enrichment Score (NES) | -1.8086877 |
Nominal p-value | 0.0 |
FDR q-value | 0.012413266 |
FWER p-Value | 0.098 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | WNT5B | 5080162 | 71 | 4.385 | 0.0186 | No | ||
2 | GIPC1 | 4590348 5570438 5900707 | 495 | 2.726 | 0.0096 | No | ||
3 | MID1IP1 | 2570739 | 499 | 2.723 | 0.0233 | No | ||
4 | BUB3 | 3170546 | 627 | 2.521 | 0.0293 | No | ||
5 | HSPA8 | 2120315 1050132 6550746 | 930 | 2.090 | 0.0236 | No | ||
6 | LHFPL2 | 450020 | 1124 | 1.894 | 0.0229 | No | ||
7 | UBE2C | 6130017 | 1159 | 1.873 | 0.0306 | No | ||
8 | ZDHHC16 | 4230390 | 1319 | 1.722 | 0.0308 | No | ||
9 | RBM14 | 5340731 5690315 | 1352 | 1.692 | 0.0377 | No | ||
10 | ARFGAP1 | 4780364 5390358 | 1370 | 1.676 | 0.0453 | No | ||
11 | FKBP1A | 2450368 | 1524 | 1.554 | 0.0450 | No | ||
12 | BAG2 | 2900324 | 1539 | 1.540 | 0.0521 | No | ||
13 | SLC2A1 | 2100609 | 1676 | 1.465 | 0.0522 | No | ||
14 | PANX1 | 6550632 | 1758 | 1.406 | 0.0550 | No | ||
15 | SON | 3120148 5860239 7040403 | 1865 | 1.303 | 0.0559 | No | ||
16 | ARHGEF2 | 3360577 | 1901 | 1.274 | 0.0606 | No | ||
17 | TARDBP | 870390 2350093 | 2211 | 1.070 | 0.0493 | No | ||
18 | KIAA0859 | 510497 770722 1340687 6840711 | 2414 | 0.963 | 0.0432 | No | ||
19 | DNAJA2 | 2630253 6860358 | 2415 | 0.960 | 0.0482 | No | ||
20 | ADSL | 5570484 | 2502 | 0.908 | 0.0481 | No | ||
21 | SFRS9 | 3800047 | 2527 | 0.890 | 0.0514 | No | ||
22 | TOP1 | 770471 4060632 6650324 | 2641 | 0.831 | 0.0495 | No | ||
23 | PSMA5 | 5390537 | 3139 | 0.596 | 0.0256 | No | ||
24 | DLG5 | 450215 | 3210 | 0.570 | 0.0247 | No | ||
25 | FAS | 4480112 6110040 | 3448 | 0.488 | 0.0144 | No | ||
26 | CHST2 | 3180682 | 3455 | 0.485 | 0.0165 | No | ||
27 | MTMR4 | 4540524 | 3460 | 0.484 | 0.0188 | No | ||
28 | EIF3S10 | 1190079 3840176 | 3518 | 0.465 | 0.0181 | No | ||
29 | ERCC3 | 6900008 | 3556 | 0.456 | 0.0184 | No | ||
30 | ANLN | 1780113 2470537 6840047 | 3777 | 0.399 | 0.0085 | No | ||
31 | FADD | 2360593 4210692 6520019 | 3820 | 0.392 | 0.0083 | No | ||
32 | JMJD2B | 6350372 6400471 | 3840 | 0.387 | 0.0092 | No | ||
33 | PAPPA | 4230463 | 3954 | 0.361 | 0.0049 | No | ||
34 | GCNT1 | 940129 1780215 2370253 | 4101 | 0.334 | -0.0013 | No | ||
35 | SNIP1 | 5360092 | 4165 | 0.323 | -0.0030 | No | ||
36 | BLZF1 | 630088 | 4177 | 0.321 | -0.0020 | No | ||
37 | RNF14 | 50402 1340041 6370687 | 4287 | 0.302 | -0.0064 | No | ||
38 | PDGFB | 3060440 6370008 | 4904 | 0.217 | -0.0386 | No | ||
39 | HSPE1 | 3170438 | 4965 | 0.210 | -0.0408 | No | ||
40 | BUB1 | 5390270 | 5073 | 0.197 | -0.0456 | No | ||
41 | PLAG1 | 1450142 3870139 6520039 | 5097 | 0.194 | -0.0459 | No | ||
42 | CORO1C | 4570397 | 5174 | 0.186 | -0.0490 | No | ||
43 | HS3ST3B1 | 380040 | 5372 | 0.169 | -0.0588 | No | ||
44 | CRSP6 | 2940358 | 5637 | 0.150 | -0.0724 | No | ||
45 | RCC1 | 2480358 | 5687 | 0.146 | -0.0743 | No | ||
46 | B4GALT5 | 1230692 | 5916 | 0.129 | -0.0860 | No | ||
47 | NUFIP1 | 6350241 | 6438 | 0.100 | -0.1137 | No | ||
48 | THRAP3 | 6180309 | 6878 | 0.082 | -0.1371 | No | ||
49 | ACTL6A | 5220543 6290541 2450093 4590332 5270722 | 7052 | 0.076 | -0.1461 | No | ||
50 | RBM27 | 4050603 | 7059 | 0.076 | -0.1460 | No | ||
51 | CXXC5 | 840010 | 7155 | 0.073 | -0.1508 | No | ||
52 | TDG | 2900358 2940079 | 7217 | 0.071 | -0.1537 | No | ||
53 | PRKD3 | 5220520 5890519 | 7355 | 0.066 | -0.1608 | No | ||
54 | MRPL1 | 430626 3130129 5220152 | 7358 | 0.066 | -0.1606 | No | ||
55 | IL1RL1 | 3990224 6020347 | 7370 | 0.065 | -0.1609 | No | ||
56 | CDK7 | 2640451 | 7569 | 0.060 | -0.1713 | No | ||
57 | IPO7 | 2190746 | 7698 | 0.057 | -0.1779 | No | ||
58 | CDH11 | 1230133 2100180 4610110 | 7772 | 0.055 | -0.1816 | No | ||
59 | FBXL7 | 6620711 | 7955 | 0.051 | -0.1912 | No | ||
60 | FZD1 | 3140215 | 8078 | 0.048 | -0.1976 | No | ||
61 | GTF2H1 | 2570746 2650148 | 8154 | 0.047 | -0.2014 | No | ||
62 | FOSL1 | 430021 | 8299 | 0.043 | -0.2090 | No | ||
63 | CPT1A | 6350093 | 8589 | 0.038 | -0.2245 | No | ||
64 | SMARCA5 | 6620050 | 8953 | 0.030 | -0.2440 | No | ||
65 | MTIF2 | 2260270 | 9041 | 0.028 | -0.2486 | No | ||
66 | NCOA6 | 1780333 6450110 | 9071 | 0.027 | -0.2500 | No | ||
67 | CTGF | 4540577 | 9479 | 0.020 | -0.2719 | No | ||
68 | JAG1 | 3440390 | 9767 | 0.015 | -0.2874 | No | ||
69 | LYN | 6040600 | 9800 | 0.015 | -0.2891 | No | ||
70 | EPS8 | 7050204 | 9837 | 0.014 | -0.2910 | No | ||
71 | XRCC5 | 7100286 | 10724 | -0.001 | -0.3390 | No | ||
72 | TIAM2 | 360195 | 10839 | -0.003 | -0.3451 | No | ||
73 | EPS15 | 4200215 | 10846 | -0.003 | -0.3455 | No | ||
74 | CRK | 1230162 4780128 | 10922 | -0.004 | -0.3495 | No | ||
75 | BIRC6 | 70148 | 10935 | -0.004 | -0.3501 | No | ||
76 | ATG5 | 6200433 5360324 | 11030 | -0.006 | -0.3552 | No | ||
77 | SEH1L | 4590563 | 11070 | -0.007 | -0.3573 | No | ||
78 | MFAP1 | 6660092 | 11338 | -0.011 | -0.3717 | No | ||
79 | SPRY2 | 5860184 | 11448 | -0.014 | -0.3775 | No | ||
80 | RAB5A | 6520324 | 11473 | -0.014 | -0.3788 | No | ||
81 | VEGFC | 5910494 | 11694 | -0.018 | -0.3906 | No | ||
82 | CFLAR | 2320605 6180440 | 12498 | -0.036 | -0.4339 | No | ||
83 | CDC25C | 2570673 4760161 6520707 | 12613 | -0.040 | -0.4399 | No | ||
84 | GDI2 | 2370068 | 12910 | -0.048 | -0.4557 | No | ||
85 | GOPC | 6620400 | 13245 | -0.060 | -0.4735 | No | ||
86 | CYHR1 | 940609 2810463 3190332 3290692 4280411 | 13267 | -0.061 | -0.4743 | No | ||
87 | ACSL3 | 3140195 | 13515 | -0.072 | -0.4873 | No | ||
88 | GGPS1 | 840128 2320215 | 13632 | -0.077 | -0.4932 | No | ||
89 | HSPA1L | 4010538 | 13779 | -0.087 | -0.5007 | No | ||
90 | SSFA2 | 3870133 | 13843 | -0.091 | -0.5037 | No | ||
91 | PSMB1 | 2940402 | 14659 | -0.186 | -0.5469 | No | ||
92 | CDC23 | 3190593 | 14662 | -0.186 | -0.5460 | No | ||
93 | ARFGEF2 | 5550500 | 14812 | -0.216 | -0.5530 | No | ||
94 | FNDC3A | 2690097 3290044 | 14981 | -0.255 | -0.5608 | No | ||
95 | USP12 | 6130735 6620280 | 15158 | -0.309 | -0.5688 | No | ||
96 | WEE1 | 3390070 | 15186 | -0.317 | -0.5686 | No | ||
97 | MYC | 380541 4670170 | 15244 | -0.337 | -0.5700 | No | ||
98 | FBXL3 | 5910142 | 15350 | -0.371 | -0.5738 | No | ||
99 | EML4 | 5700373 | 15414 | -0.390 | -0.5752 | No | ||
100 | STK17B | 130091 | 15418 | -0.393 | -0.5733 | No | ||
101 | CCNA2 | 5290075 | 15560 | -0.440 | -0.5787 | No | ||
102 | GABPB2 | 6130450 7050735 | 15566 | -0.444 | -0.5767 | No | ||
103 | BIRC2 | 2940435 4730020 | 15732 | -0.505 | -0.5831 | No | ||
104 | BCL2L1 | 1580452 4200152 5420484 | 15795 | -0.530 | -0.5838 | No | ||
105 | CLCN7 | 2970095 | 15849 | -0.555 | -0.5838 | No | ||
106 | XBP1 | 3840594 | 15872 | -0.564 | -0.5821 | No | ||
107 | TCERG1 | 2350551 4540397 5220746 | 15978 | -0.615 | -0.5846 | No | ||
108 | MCM3 | 5570068 | 16006 | -0.627 | -0.5829 | No | ||
109 | MRPL35 | 1990671 | 16042 | -0.644 | -0.5815 | No | ||
110 | PSMC6 | 2810021 | 16287 | -0.776 | -0.5908 | No | ||
111 | GTF2B | 6860685 | 16353 | -0.810 | -0.5901 | No | ||
112 | TNFSF5IP1 | 2060095 | 16550 | -0.929 | -0.5960 | Yes | ||
113 | MAT2A | 4070026 4730079 6020280 | 16565 | -0.938 | -0.5920 | Yes | ||
114 | PPP1CC | 6380300 2510647 | 16673 | -0.993 | -0.5927 | Yes | ||
115 | RPS7 | 6860113 | 16749 | -1.033 | -0.5915 | Yes | ||
116 | CDC5L | 3130446 3390025 6400204 | 16764 | -1.043 | -0.5869 | Yes | ||
117 | ELOVL6 | 5340746 | 16791 | -1.064 | -0.5829 | Yes | ||
118 | PRIM2A | 7000692 | 16825 | -1.081 | -0.5791 | Yes | ||
119 | SIRPA | 130465 5700332 | 16863 | -1.108 | -0.5755 | Yes | ||
120 | MRPL15 | 360390 | 16881 | -1.128 | -0.5706 | Yes | ||
121 | USP3 | 2060332 | 16935 | -1.162 | -0.5676 | Yes | ||
122 | SNRPG | 2340551 | 16961 | -1.180 | -0.5629 | Yes | ||
123 | SUPV3L1 | 1170072 | 17004 | -1.229 | -0.5589 | Yes | ||
124 | PJA2 | 430537 | 17072 | -1.296 | -0.5559 | Yes | ||
125 | RIPK1 | 3190025 | 17073 | -1.297 | -0.5493 | Yes | ||
126 | OGT | 2360131 4610333 | 17074 | -1.298 | -0.5426 | Yes | ||
127 | GNL2 | 6620022 | 17133 | -1.362 | -0.5388 | Yes | ||
128 | RBM17 | 870592 | 17191 | -1.417 | -0.5347 | Yes | ||
129 | TXNRD1 | 6590446 | 17271 | -1.508 | -0.5312 | Yes | ||
130 | UBE2D3 | 3190452 | 17364 | -1.609 | -0.5280 | Yes | ||
131 | SIRT1 | 1190731 | 17426 | -1.676 | -0.5227 | Yes | ||
132 | PSMD12 | 730044 | 17438 | -1.690 | -0.5147 | Yes | ||
133 | TOP2A | 360717 | 17451 | -1.703 | -0.5066 | Yes | ||
134 | MCTS1 | 6130133 | 17468 | -1.732 | -0.4987 | Yes | ||
135 | MAPK14 | 5290731 | 17476 | -1.736 | -0.4902 | Yes | ||
136 | FNTA | 70059 | 17541 | -1.808 | -0.4844 | Yes | ||
137 | ATP2A2 | 1090075 3990279 | 17677 | -1.987 | -0.4815 | Yes | ||
138 | RABGGTB | 3120037 | 17731 | -2.067 | -0.4739 | Yes | ||
139 | ZDHHC5 | 1690711 | 17740 | -2.080 | -0.4637 | Yes | ||
140 | EIF4B | 5390563 5270577 | 17772 | -2.116 | -0.4545 | Yes | ||
141 | PPP2R5E | 70671 2120056 | 17840 | -2.202 | -0.4469 | Yes | ||
142 | UBE2D2 | 4590671 6510446 | 17855 | -2.229 | -0.4363 | Yes | ||
143 | MAP3K7 | 6040068 | 17946 | -2.361 | -0.4291 | Yes | ||
144 | EXOC2 | 3190132 | 18096 | -2.677 | -0.4235 | Yes | ||
145 | PPP2CB | 5570593 | 18113 | -2.711 | -0.4105 | Yes | ||
146 | POLD3 | 6400278 | 18117 | -2.715 | -0.3968 | Yes | ||
147 | DDX21 | 6100446 | 18207 | -2.918 | -0.3867 | Yes | ||
148 | PIK3C3 | 6590717 | 18230 | -2.975 | -0.3726 | Yes | ||
149 | PSMA4 | 4560427 | 18265 | -3.059 | -0.3589 | Yes | ||
150 | PCNA | 940754 | 18279 | -3.090 | -0.3438 | Yes | ||
151 | RABGAP1 | 5050397 | 18290 | -3.128 | -0.3283 | Yes | ||
152 | SLC25A17 | 2100369 | 18292 | -3.137 | -0.3123 | Yes | ||
153 | TBK1 | 5690338 | 18325 | -3.258 | -0.2974 | Yes | ||
154 | RAB1A | 2370671 | 18364 | -3.405 | -0.2821 | Yes | ||
155 | EMP1 | 4120438 | 18396 | -3.541 | -0.2656 | Yes | ||
156 | CCNH | 3190347 | 18401 | -3.563 | -0.2477 | Yes | ||
157 | RAP1B | 3710138 | 18463 | -3.825 | -0.2314 | Yes | ||
158 | CCT4 | 6380161 | 18499 | -4.044 | -0.2126 | Yes | ||
159 | GTF2H2 | 5130358 | 18509 | -4.126 | -0.1920 | Yes | ||
160 | SRPK2 | 6380341 | 18529 | -4.282 | -0.1712 | Yes | ||
161 | HSPH1 | 1690017 | 18532 | -4.292 | -0.1493 | Yes | ||
162 | DDX20 | 3290348 | 18537 | -4.358 | -0.1273 | Yes | ||
163 | TMPO | 4050494 | 18542 | -4.448 | -0.1048 | Yes | ||
164 | SMAD4 | 5670519 | 18544 | -4.465 | -0.0820 | Yes | ||
165 | SLC4A1AP | 3190576 | 18566 | -4.754 | -0.0588 | Yes | ||
166 | HDAC2 | 4050433 | 18596 | -5.359 | -0.0330 | Yes | ||
167 | LBR | 4540671 | 18614 | -6.656 | 0.0001 | Yes |