Dataset | Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch_repos |
Phenotype | phenotype_absentNotch_versus_wtNotch.cls#absentNotch_versus_wtNotch_repos |
Upregulated in class | absentNotch |
GeneSet | V$USF_02 |
Enrichment Score (ES) | 0.5416249 |
Normalized Enrichment Score (NES) | 1.6399434 |
Nominal p-value | 0.0 |
FDR q-value | 0.2036683 |
FWER p-Value | 0.27 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PER1 | 3290315 | 76 | 2.373 | 0.0288 | Yes | ||
2 | PFDN2 | 4230156 | 79 | 2.348 | 0.0613 | Yes | ||
3 | DUSP1 | 6860121 | 125 | 2.179 | 0.0892 | Yes | ||
4 | KBTBD2 | 2320014 | 128 | 2.165 | 0.1191 | Yes | ||
5 | EIF4B | 5390563 5270577 | 143 | 2.090 | 0.1474 | Yes | ||
6 | SNX8 | 3450315 | 171 | 2.000 | 0.1737 | Yes | ||
7 | NUDC | 4780025 | 224 | 1.882 | 0.1970 | Yes | ||
8 | GRN | 4050239 | 236 | 1.839 | 0.2220 | Yes | ||
9 | GPX1 | 4150093 | 262 | 1.759 | 0.2450 | Yes | ||
10 | UTP14A | 6590048 | 293 | 1.694 | 0.2669 | Yes | ||
11 | RHEBL1 | 2810576 | 350 | 1.591 | 0.2860 | Yes | ||
12 | MTCH2 | 3780603 6620215 | 368 | 1.571 | 0.3069 | Yes | ||
13 | UBE4B | 780008 3610154 | 453 | 1.473 | 0.3228 | Yes | ||
14 | AKAP12 | 1450739 | 522 | 1.383 | 0.3383 | Yes | ||
15 | ALDH6A1 | 1770746 | 673 | 1.249 | 0.3475 | Yes | ||
16 | PABPC1 | 2650180 2690253 6020632 1990270 | 819 | 1.149 | 0.3556 | Yes | ||
17 | COMMD3 | 2510259 | 828 | 1.142 | 0.3710 | Yes | ||
18 | DDX3X | 2190020 | 857 | 1.115 | 0.3850 | Yes | ||
19 | PTMA | 5570148 | 933 | 1.061 | 0.3957 | Yes | ||
20 | NIT1 | 1230338 3940671 | 1064 | 0.999 | 0.4025 | Yes | ||
21 | TIMM8A | 110279 | 1173 | 0.952 | 0.4098 | Yes | ||
22 | CD164 | 3830594 | 1175 | 0.949 | 0.4230 | Yes | ||
23 | MCAM | 5130270 6620577 | 1223 | 0.917 | 0.4332 | Yes | ||
24 | H2AFY | 4730750 | 1263 | 0.896 | 0.4435 | Yes | ||
25 | ATP6V1C1 | 2690324 5220528 | 1311 | 0.865 | 0.4529 | Yes | ||
26 | RAB9A | 1690279 3710671 | 1357 | 0.845 | 0.4622 | Yes | ||
27 | DCTN4 | 3390010 5550170 | 1627 | 0.716 | 0.4576 | Yes | ||
28 | CLN3 | 780368 | 1720 | 0.678 | 0.4620 | Yes | ||
29 | ATF7IP | 2690176 6770021 | 1803 | 0.642 | 0.4665 | Yes | ||
30 | UBXD3 | 5050193 | 1812 | 0.638 | 0.4749 | Yes | ||
31 | BAX | 3830008 | 1838 | 0.628 | 0.4823 | Yes | ||
32 | EIF4E | 1580403 70133 6380215 | 1940 | 0.587 | 0.4850 | Yes | ||
33 | GPR65 | 3120551 | 2118 | 0.525 | 0.4826 | Yes | ||
34 | ASNA1 | 3830041 | 2121 | 0.524 | 0.4898 | Yes | ||
35 | AATF | 5220575 | 2180 | 0.505 | 0.4937 | Yes | ||
36 | TCF12 | 3610324 7000156 | 2257 | 0.484 | 0.4963 | Yes | ||
37 | CYR61 | 1240408 5290026 4120452 6550008 | 2276 | 0.480 | 0.5020 | Yes | ||
38 | COMMD8 | 5890358 | 2339 | 0.455 | 0.5049 | Yes | ||
39 | TCERG1 | 2350551 4540397 5220746 | 2366 | 0.445 | 0.5097 | Yes | ||
40 | TOPORS | 4060592 | 2373 | 0.443 | 0.5155 | Yes | ||
41 | RAI14 | 770288 1660075 | 2460 | 0.421 | 0.5167 | Yes | ||
42 | PPM1A | 1170301 5900273 | 2501 | 0.410 | 0.5202 | Yes | ||
43 | SQSTM1 | 6550056 | 2548 | 0.399 | 0.5233 | Yes | ||
44 | UBE2L6 | 60048 1170687 | 2594 | 0.388 | 0.5262 | Yes | ||
45 | SLC31A2 | 1450577 | 2608 | 0.384 | 0.5309 | Yes | ||
46 | TNRC15 | 6760746 | 2616 | 0.382 | 0.5358 | Yes | ||
47 | EPC1 | 1570050 5290095 6900193 | 2623 | 0.380 | 0.5407 | Yes | ||
48 | GABARAP | 1450286 | 2700 | 0.360 | 0.5416 | Yes | ||
49 | RAB3IL1 | 380685 5420176 | 2864 | 0.323 | 0.5373 | No | ||
50 | CDKN2C | 5050750 5130148 | 3036 | 0.286 | 0.5320 | No | ||
51 | SIRT1 | 1190731 | 3302 | 0.239 | 0.5209 | No | ||
52 | SYNPO2L | 5390719 | 3384 | 0.228 | 0.5197 | No | ||
53 | DNAJB5 | 2900215 | 3406 | 0.226 | 0.5217 | No | ||
54 | BLNK | 70288 6590092 | 3432 | 0.222 | 0.5234 | No | ||
55 | KCNE4 | 2470102 | 3446 | 0.220 | 0.5257 | No | ||
56 | LAMC2 | 450692 2680041 4200059 4670148 | 3601 | 0.199 | 0.5202 | No | ||
57 | RUNX1 | 3840711 | 3747 | 0.183 | 0.5148 | No | ||
58 | SSR1 | 5890100 | 3766 | 0.180 | 0.5164 | No | ||
59 | SLC23A2 | 6660722 | 3933 | 0.164 | 0.5096 | No | ||
60 | GNB2 | 2350053 | 4180 | 0.142 | 0.4983 | No | ||
61 | TOP3A | 7000435 | 4362 | 0.129 | 0.4902 | No | ||
62 | SMCR8 | 730653 | 4499 | 0.120 | 0.4845 | No | ||
63 | GGN | 1410528 4210082 5290170 | 4605 | 0.113 | 0.4804 | No | ||
64 | NPTX1 | 3710736 | 4654 | 0.111 | 0.4793 | No | ||
65 | TGFB2 | 4920292 | 4739 | 0.105 | 0.4762 | No | ||
66 | ETV1 | 70735 2940603 5080463 | 4991 | 0.094 | 0.4639 | No | ||
67 | ZIC3 | 380020 | 5692 | 0.068 | 0.4269 | No | ||
68 | APLN | 6620632 | 6051 | 0.057 | 0.4083 | No | ||
69 | VLDLR | 870722 3060047 5340452 6550131 | 6132 | 0.055 | 0.4047 | No | ||
70 | TYR | 5690139 | 6221 | 0.053 | 0.4007 | No | ||
71 | FOXD3 | 6550156 | 6234 | 0.053 | 0.4008 | No | ||
72 | SUMF1 | 730050 | 6251 | 0.053 | 0.4006 | No | ||
73 | CRLF1 | 3520092 | 6400 | 0.049 | 0.3933 | No | ||
74 | NPM1 | 4730427 | 6501 | 0.046 | 0.3885 | No | ||
75 | UMPS | 2340541 4730438 | 6512 | 0.046 | 0.3886 | No | ||
76 | PIP5K1A | 4560672 | 6681 | 0.042 | 0.3801 | No | ||
77 | LHFP | 3440368 | 6914 | 0.038 | 0.3680 | No | ||
78 | POGK | 5290315 | 6946 | 0.037 | 0.3668 | No | ||
79 | CPT1A | 6350093 | 7251 | 0.031 | 0.3508 | No | ||
80 | PICALM | 1940280 | 7366 | 0.030 | 0.3450 | No | ||
81 | FMR1 | 5050075 | 7485 | 0.028 | 0.3390 | No | ||
82 | HOXA11 | 6980133 | 7781 | 0.023 | 0.3233 | No | ||
83 | CLCN5 | 4200390 | 7785 | 0.023 | 0.3235 | No | ||
84 | TOM1L2 | 4810465 | 8120 | 0.018 | 0.3056 | No | ||
85 | MTHFD1 | 5900398 6520427 | 8184 | 0.017 | 0.3024 | No | ||
86 | PPARGC1A | 4670040 | 8383 | 0.014 | 0.2919 | No | ||
87 | SLC17A2 | 870593 2810035 | 8602 | 0.011 | 0.2802 | No | ||
88 | CBX5 | 3830072 6290167 | 8613 | 0.010 | 0.2798 | No | ||
89 | UBXD2 | 4280092 | 8672 | 0.010 | 0.2768 | No | ||
90 | HOXC5 | 1580017 | 8766 | 0.008 | 0.2718 | No | ||
91 | DNMT3A | 4050068 4810717 | 8894 | 0.006 | 0.2650 | No | ||
92 | LIN28 | 6590672 | 9003 | 0.005 | 0.2593 | No | ||
93 | CAPN6 | 1740168 | 9022 | 0.005 | 0.2583 | No | ||
94 | FZD6 | 360288 | 9067 | 0.004 | 0.2560 | No | ||
95 | XPO1 | 540707 | 9072 | 0.004 | 0.2559 | No | ||
96 | PFKFB1 | 2370128 | 9120 | 0.004 | 0.2534 | No | ||
97 | LRP5 | 2100397 3170484 | 9158 | 0.003 | 0.2514 | No | ||
98 | AP1S2 | 780279 4280707 | 9161 | 0.003 | 0.2513 | No | ||
99 | HOXB5 | 2900538 | 9272 | 0.001 | 0.2454 | No | ||
100 | HOXD10 | 6100039 | 9479 | -0.002 | 0.2342 | No | ||
101 | CARKL | 6020068 | 9569 | -0.003 | 0.2294 | No | ||
102 | EIF3S10 | 1190079 3840176 | 9662 | -0.004 | 0.2245 | No | ||
103 | BMP6 | 2100128 | 9712 | -0.005 | 0.2219 | No | ||
104 | ILF3 | 940722 3190647 6520110 | 9953 | -0.008 | 0.2090 | No | ||
105 | PIK3R1 | 4730671 | 9986 | -0.008 | 0.2074 | No | ||
106 | MAT2A | 4070026 4730079 6020280 | 10116 | -0.010 | 0.2005 | No | ||
107 | RHOQ | 520161 | 10185 | -0.012 | 0.1970 | No | ||
108 | BTBD14B | 3520601 4280162 | 10403 | -0.015 | 0.1854 | No | ||
109 | CALR | 510446 | 10559 | -0.017 | 0.1773 | No | ||
110 | UBE2B | 4780497 | 10616 | -0.018 | 0.1745 | No | ||
111 | LAMA3 | 1190131 5290239 | 10660 | -0.019 | 0.1724 | No | ||
112 | HNRPD | 4120021 | 10669 | -0.019 | 0.1722 | No | ||
113 | C4A | 360286 3830100 5220750 6420132 | 10821 | -0.021 | 0.1643 | No | ||
114 | CREB5 | 2320368 | 10840 | -0.021 | 0.1637 | No | ||
115 | VNN1 | 3940400 | 11051 | -0.025 | 0.1526 | No | ||
116 | PLS3 | 3290082 | 11495 | -0.033 | 0.1290 | No | ||
117 | NCOA6 | 1780333 6450110 | 11496 | -0.033 | 0.1295 | No | ||
118 | ELAVL3 | 2850014 | 11765 | -0.038 | 0.1155 | No | ||
119 | OMG | 6760066 | 12007 | -0.043 | 0.1030 | No | ||
120 | MAX | 5220021 | 12027 | -0.043 | 0.1026 | No | ||
121 | SLC1A7 | 1990181 | 12038 | -0.043 | 0.1027 | No | ||
122 | GZMK | 1410148 | 12046 | -0.044 | 0.1029 | No | ||
123 | IRS4 | 430341 1190450 | 12103 | -0.045 | 0.1005 | No | ||
124 | GLA | 4610364 | 12268 | -0.049 | 0.0923 | No | ||
125 | SLC12A6 | 610278 1980035 5340671 | 12705 | -0.060 | 0.0694 | No | ||
126 | BDNF | 2940128 3520368 | 12822 | -0.064 | 0.0640 | No | ||
127 | SEC23IP | 4540484 6200047 | 12837 | -0.064 | 0.0642 | No | ||
128 | HNRPH2 | 2630040 5720671 | 12847 | -0.065 | 0.0646 | No | ||
129 | CTNS | 4480048 | 12946 | -0.068 | 0.0602 | No | ||
130 | TAC1 | 7000195 380706 | 12971 | -0.069 | 0.0599 | No | ||
131 | DVL2 | 6110162 | 12999 | -0.070 | 0.0594 | No | ||
132 | RNF128 | 1230300 5670273 | 13167 | -0.077 | 0.0514 | No | ||
133 | FGF14 | 2630390 3520075 6770048 | 13250 | -0.079 | 0.0480 | No | ||
134 | STK16 | 1740154 | 13572 | -0.093 | 0.0319 | No | ||
135 | SUPV3L1 | 1170072 | 13755 | -0.102 | 0.0235 | No | ||
136 | NRIP3 | 1340372 | 13833 | -0.106 | 0.0208 | No | ||
137 | SEMA3A | 1780064 | 14025 | -0.117 | 0.0120 | No | ||
138 | COPZ1 | 6940100 | 14122 | -0.123 | 0.0086 | No | ||
139 | HOXB7 | 4540706 4610358 | 14123 | -0.123 | 0.0103 | No | ||
140 | RPS28 | 3830221 | 14126 | -0.124 | 0.0119 | No | ||
141 | MDM1 | 510528 1780280 2680152 2690181 3060025 3120487 4210601 4540037 4610142 5290110 6400433 6480743 | 14171 | -0.127 | 0.0112 | No | ||
142 | SOX10 | 6200538 | 14283 | -0.134 | 0.0071 | No | ||
143 | RFC1 | 1190673 | 14362 | -0.140 | 0.0048 | No | ||
144 | NEUROD1 | 3060619 | 14437 | -0.145 | 0.0028 | No | ||
145 | TAF6L | 1850056 | 14438 | -0.145 | 0.0048 | No | ||
146 | TESK2 | 6520524 | 14461 | -0.147 | 0.0057 | No | ||
147 | SLC39A5 | 2900100 4610440 | 14482 | -0.149 | 0.0066 | No | ||
148 | EGLN2 | 540086 | 14556 | -0.156 | 0.0048 | No | ||
149 | RPS2 | 1340647 | 14597 | -0.160 | 0.0049 | No | ||
150 | FEN1 | 1770541 | 14598 | -0.160 | 0.0071 | No | ||
151 | DUSP8 | 6650039 | 14730 | -0.171 | 0.0024 | No | ||
152 | NFX1 | 450504 | 14739 | -0.172 | 0.0044 | No | ||
153 | ARMET | 5130670 | 14800 | -0.178 | 0.0036 | No | ||
154 | HNRPA1 | 4670398 5050687 | 14863 | -0.184 | 0.0028 | No | ||
155 | DUSP7 | 2940309 | 15078 | -0.207 | -0.0060 | No | ||
156 | ATP6V1A | 6590242 | 15291 | -0.234 | -0.0142 | No | ||
157 | ISGF3G | 3190131 7100142 | 15323 | -0.240 | -0.0125 | No | ||
158 | GTF2A1 | 4120138 4920524 5390110 1230397 | 15526 | -0.274 | -0.0197 | No | ||
159 | MAP4K1 | 4060692 | 15584 | -0.284 | -0.0188 | No | ||
160 | DDIT3 | 780373 | 15630 | -0.290 | -0.0173 | No | ||
161 | STC2 | 4920601 | 15717 | -0.306 | -0.0177 | No | ||
162 | UROD | 2470494 | 15772 | -0.315 | -0.0162 | No | ||
163 | DHX35 | 1230440 | 15805 | -0.322 | -0.0135 | No | ||
164 | BRDT | 3940102 | 15913 | -0.342 | -0.0145 | No | ||
165 | ARPP-19 | 5700025 | 15945 | -0.350 | -0.0114 | No | ||
166 | MRPL27 | 2060131 | 16007 | -0.363 | -0.0096 | No | ||
167 | GTF2H1 | 2570746 2650148 | 16213 | -0.412 | -0.0150 | No | ||
168 | HIVEP1 | 3850632 | 16240 | -0.420 | -0.0106 | No | ||
169 | NDUFA7 | 5900722 | 16396 | -0.467 | -0.0125 | No | ||
170 | PRPS1 | 6350129 | 16555 | -0.513 | -0.0140 | No | ||
171 | COQ4 | 1660551 | 16783 | -0.585 | -0.0182 | No | ||
172 | ATF4 | 730441 1740195 | 16803 | -0.593 | -0.0110 | No | ||
173 | CCAR1 | 3190092 | 17272 | -0.777 | -0.0255 | No | ||
174 | VPS16 | 430064 3390041 6860301 | 17503 | -0.893 | -0.0256 | No | ||
175 | OPRS1 | 6130128 6290717 | 17771 | -1.032 | -0.0258 | No | ||
176 | ZFYVE26 | 6860152 | 17806 | -1.060 | -0.0129 | No | ||
177 | SESN3 | 110687 | 18034 | -1.234 | -0.0081 | No | ||
178 | PTGES2 | 4210097 | 18208 | -1.422 | 0.0023 | No | ||
179 | CHD4 | 5420059 6130338 6380717 | 18210 | -1.424 | 0.0220 | No |