Dataset | Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch_repos |
Phenotype | phenotype_absentNotch_versus_wtNotch.cls#absentNotch_versus_wtNotch_repos |
Upregulated in class | wtNotch |
GeneSet | V$HNF4_01 |
Enrichment Score (ES) | -0.39095718 |
Normalized Enrichment Score (NES) | -1.2249161 |
Nominal p-value | 0.053140096 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | SEPP1 | 450273 | 110 | 2.219 | 0.0283 | No | ||
2 | HSPE1 | 3170438 | 309 | 1.669 | 0.0434 | No | ||
3 | BCL11B | 2680673 | 462 | 1.464 | 0.0578 | No | ||
4 | SATB1 | 5670154 | 526 | 1.381 | 0.0757 | No | ||
5 | MAGMAS | 580064 4920452 | 849 | 1.118 | 0.0755 | No | ||
6 | RBMS1 | 6400014 | 962 | 1.040 | 0.0855 | No | ||
7 | RHOB | 1500309 | 1148 | 0.964 | 0.0904 | No | ||
8 | GPD1 | 2480095 | 1274 | 0.886 | 0.0973 | No | ||
9 | MRPS28 | 2230373 | 1368 | 0.840 | 0.1052 | No | ||
10 | IGF1R | 3360494 | 1474 | 0.786 | 0.1117 | No | ||
11 | SMOC1 | 840039 | 1496 | 0.777 | 0.1225 | No | ||
12 | LRFN4 | 5670368 | 1557 | 0.751 | 0.1309 | No | ||
13 | RNF103 | 840452 | 1866 | 0.618 | 0.1237 | No | ||
14 | SFRS6 | 60224 | 1934 | 0.590 | 0.1292 | No | ||
15 | POLR2H | 5890242 | 2064 | 0.546 | 0.1306 | No | ||
16 | LRP1 | 6270386 | 2124 | 0.524 | 0.1355 | No | ||
17 | PCTK1 | 4560079 | 2172 | 0.506 | 0.1408 | No | ||
18 | SMYD5 | 6220025 | 2400 | 0.435 | 0.1352 | No | ||
19 | G6PC | 430093 | 2475 | 0.416 | 0.1376 | No | ||
20 | GATA4 | 1410215 2690609 | 2506 | 0.409 | 0.1423 | No | ||
21 | OVOL1 | 1690131 | 2515 | 0.406 | 0.1482 | No | ||
22 | APOM | 2340010 | 2605 | 0.385 | 0.1493 | No | ||
23 | SELM | 450458 | 2856 | 0.325 | 0.1408 | No | ||
24 | PABPN1 | 460519 | 3044 | 0.285 | 0.1350 | No | ||
25 | PPARG | 1990168 2680603 6130632 | 3098 | 0.276 | 0.1364 | No | ||
26 | NEK6 | 3360687 | 3118 | 0.272 | 0.1396 | No | ||
27 | AKAP11 | 5050685 | 3169 | 0.261 | 0.1409 | No | ||
28 | INSR | 1190504 | 3250 | 0.247 | 0.1404 | No | ||
29 | CACNB2 | 1500095 7330707 | 3340 | 0.234 | 0.1392 | No | ||
30 | SNAP25 | 360520 | 3381 | 0.228 | 0.1405 | No | ||
31 | DAB2IP | 3170064 6200441 | 3493 | 0.212 | 0.1378 | No | ||
32 | SLC25A4 | 2360519 | 3610 | 0.198 | 0.1345 | No | ||
33 | SCT | 2230348 | 3681 | 0.191 | 0.1337 | No | ||
34 | PIP5K2A | 5220497 | 3682 | 0.191 | 0.1367 | No | ||
35 | SLC23A3 | 6840152 | 3744 | 0.183 | 0.1362 | No | ||
36 | UBE4A | 6100520 | 3862 | 0.169 | 0.1324 | No | ||
37 | PAPLN | 2510592 | 3959 | 0.162 | 0.1297 | No | ||
38 | ARCN1 | 5820273 | 4011 | 0.157 | 0.1294 | No | ||
39 | RNF5 | 2760088 | 4042 | 0.154 | 0.1301 | No | ||
40 | LMX1B | 1260561 | 4193 | 0.141 | 0.1242 | No | ||
41 | RBP2 | 2060097 | 4320 | 0.133 | 0.1194 | No | ||
42 | EPHA3 | 2190497 5080059 | 4581 | 0.116 | 0.1071 | No | ||
43 | TBX5 | 2900132 6370484 | 4636 | 0.112 | 0.1059 | No | ||
44 | SEMA3B | 5570563 | 4862 | 0.099 | 0.0952 | No | ||
45 | TCF1 | 5390022 | 4871 | 0.099 | 0.0963 | No | ||
46 | F10 | 3830450 | 5023 | 0.092 | 0.0895 | No | ||
47 | SOX5 | 2370576 2900167 3190128 5050528 | 5064 | 0.091 | 0.0888 | No | ||
48 | PRKCD | 770592 | 5186 | 0.086 | 0.0835 | No | ||
49 | DUSP3 | 1240129 6840215 | 5316 | 0.080 | 0.0778 | No | ||
50 | KLHL1 | 6350021 | 5374 | 0.078 | 0.0759 | No | ||
51 | PRRX2 | 4260603 | 5557 | 0.072 | 0.0671 | No | ||
52 | SPRY4 | 1570594 | 5721 | 0.067 | 0.0593 | No | ||
53 | CDX2 | 3850349 | 5788 | 0.065 | 0.0567 | No | ||
54 | PTBP2 | 1240398 | 6103 | 0.056 | 0.0405 | No | ||
55 | PKLR | 1170400 2470114 | 6361 | 0.050 | 0.0274 | No | ||
56 | SLC22A18 | 7050168 | 6509 | 0.046 | 0.0201 | No | ||
57 | SERPINF1 | 7040367 | 6790 | 0.040 | 0.0055 | No | ||
58 | PGF | 4810593 | 6879 | 0.038 | 0.0014 | No | ||
59 | HOXD3 | 6450154 | 7035 | 0.035 | -0.0065 | No | ||
60 | CREB3L2 | 3390484 | 7064 | 0.035 | -0.0075 | No | ||
61 | NR2C2 | 6100097 | 7161 | 0.033 | -0.0122 | No | ||
62 | ADAMTS19 | 2680739 | 7336 | 0.030 | -0.0212 | No | ||
63 | SLC34A1 | 430044 | 7382 | 0.029 | -0.0232 | No | ||
64 | CDH6 | 4730541 | 7479 | 0.028 | -0.0279 | No | ||
65 | NKX2-2 | 4150731 | 7522 | 0.027 | -0.0298 | No | ||
66 | PRDM1 | 3170347 3520301 | 7557 | 0.026 | -0.0312 | No | ||
67 | NDUFS1 | 2650253 | 7596 | 0.026 | -0.0329 | No | ||
68 | HR | 2690095 6200300 | 7711 | 0.024 | -0.0387 | No | ||
69 | ERBB3 | 5890372 | 7817 | 0.022 | -0.0441 | No | ||
70 | SLC7A7 | 510601 2810152 | 7892 | 0.021 | -0.0478 | No | ||
71 | PLEC1 | 6520292 50500 380075 1570088 2510692 2630497 2680017 2900746 4560497 4850376 6290398 7040471 | 8094 | 0.018 | -0.0584 | No | ||
72 | MUCDHL | 5720056 | 8151 | 0.017 | -0.0612 | No | ||
73 | EDN3 | 2690722 | 8169 | 0.017 | -0.0618 | No | ||
74 | PRDM16 | 4120541 | 8354 | 0.014 | -0.0716 | No | ||
75 | PPARGC1A | 4670040 | 8383 | 0.014 | -0.0729 | No | ||
76 | RAB33A | 6590195 | 8563 | 0.011 | -0.0824 | No | ||
77 | F13B | 6220278 | 8574 | 0.011 | -0.0828 | No | ||
78 | SNCB | 3360133 | 8630 | 0.010 | -0.0856 | No | ||
79 | NGEF | 3190538 | 8739 | 0.009 | -0.0913 | No | ||
80 | MYH10 | 2640673 | 8745 | 0.008 | -0.0915 | No | ||
81 | CALB1 | 460070 | 8880 | 0.007 | -0.0987 | No | ||
82 | TLK2 | 1170161 | 8891 | 0.007 | -0.0991 | No | ||
83 | SLC7A9 | 5420735 5700450 | 8990 | 0.005 | -0.1043 | No | ||
84 | PPARA | 2060026 | 9021 | 0.005 | -0.1059 | No | ||
85 | PFKFB1 | 2370128 | 9120 | 0.004 | -0.1112 | No | ||
86 | INHBC | 3780242 | 9138 | 0.003 | -0.1120 | No | ||
87 | WNT3 | 2360685 | 9218 | 0.002 | -0.1163 | No | ||
88 | FGF10 | 730458 840706 | 9415 | -0.001 | -0.1269 | No | ||
89 | HOXD10 | 6100039 | 9479 | -0.002 | -0.1303 | No | ||
90 | GBE1 | 2190368 | 9487 | -0.002 | -0.1307 | No | ||
91 | MLLT6 | 3870168 | 9490 | -0.002 | -0.1307 | No | ||
92 | GOLGA4 | 460300 | 9534 | -0.002 | -0.1330 | No | ||
93 | GIPC2 | 3800463 | 9732 | -0.005 | -0.1436 | No | ||
94 | EIF4G1 | 4070446 | 10031 | -0.009 | -0.1597 | No | ||
95 | LRRC19 | 2680025 | 10188 | -0.012 | -0.1680 | No | ||
96 | KYNU | 1410435 | 10247 | -0.012 | -0.1709 | No | ||
97 | AKT2 | 3850541 3870519 | 10409 | -0.015 | -0.1794 | No | ||
98 | CRABP2 | 6940725 | 10468 | -0.016 | -0.1823 | No | ||
99 | C4A | 360286 3830100 5220750 6420132 | 10821 | -0.021 | -0.2011 | No | ||
100 | DNAJA2 | 2630253 6860358 | 11093 | -0.026 | -0.2154 | No | ||
101 | SS18 | 1940440 2900072 6900129 | 11309 | -0.029 | -0.2266 | No | ||
102 | TIMELESS | 3710315 | 11391 | -0.031 | -0.2305 | No | ||
103 | SP8 | 4060576 | 11602 | -0.035 | -0.2414 | No | ||
104 | SLC26A3 | 380750 | 11680 | -0.037 | -0.2450 | No | ||
105 | NRAP | 1780433 | 11966 | -0.042 | -0.2598 | No | ||
106 | TCF2 | 870338 5050632 | 12094 | -0.045 | -0.2660 | No | ||
107 | HOXA10 | 6110397 7100458 | 12108 | -0.045 | -0.2660 | No | ||
108 | FABP2 | 5050673 | 12110 | -0.045 | -0.2654 | No | ||
109 | RARB | 430139 1410138 | 12233 | -0.048 | -0.2713 | No | ||
110 | GPR124 | 510292 6290047 | 12386 | -0.052 | -0.2787 | No | ||
111 | TRPC5 | 3390270 | 12414 | -0.053 | -0.2794 | No | ||
112 | FLNC | 2360048 5050270 | 12481 | -0.055 | -0.2821 | No | ||
113 | PITX2 | 870537 2690139 | 12609 | -0.058 | -0.2881 | No | ||
114 | SYT6 | 2510280 3850128 4540064 | 12659 | -0.059 | -0.2898 | No | ||
115 | PAX7 | 6860593 | 12692 | -0.060 | -0.2906 | No | ||
116 | PPP1R14D | 2190168 | 12859 | -0.065 | -0.2986 | No | ||
117 | SEC24C | 6980707 | 13218 | -0.078 | -0.3169 | No | ||
118 | UBE2R2 | 1230504 | 13291 | -0.081 | -0.3195 | No | ||
119 | KCNE1L | 4670092 | 13292 | -0.081 | -0.3183 | No | ||
120 | CNTFR | 4480092 6200064 | 13374 | -0.085 | -0.3213 | No | ||
121 | CREB1 | 1500717 2230358 3610600 6550601 | 13420 | -0.087 | -0.3224 | No | ||
122 | CHRDL1 | 1580037 6380204 | 13783 | -0.104 | -0.3405 | No | ||
123 | PAFAH2 | 3140451 5720593 6510014 | 13796 | -0.104 | -0.3395 | No | ||
124 | PTPRG | 2650524 1340022 | 13832 | -0.106 | -0.3398 | No | ||
125 | HOXA9 | 610494 4730040 5130601 | 13898 | -0.111 | -0.3416 | No | ||
126 | PCK1 | 7000358 | 13939 | -0.113 | -0.3420 | No | ||
127 | MAP3K11 | 7000039 | 13987 | -0.115 | -0.3428 | No | ||
128 | LRRN1 | 3290154 | 14027 | -0.117 | -0.3431 | No | ||
129 | NEUROG2 | 5420278 | 14144 | -0.124 | -0.3475 | No | ||
130 | F2 | 5720280 | 14186 | -0.127 | -0.3477 | No | ||
131 | PRKAG1 | 6450091 | 14196 | -0.128 | -0.3462 | No | ||
132 | POU5F1 | 450739 4560605 | 14314 | -0.136 | -0.3505 | No | ||
133 | LGALS4 | 2260215 3390338 | 14561 | -0.157 | -0.3614 | No | ||
134 | HSPD1 | 60097 2030451 | 14618 | -0.161 | -0.3619 | No | ||
135 | JMJD1C | 940575 2120025 | 14662 | -0.165 | -0.3617 | No | ||
136 | OBSCN | 3610129 | 14768 | -0.175 | -0.3647 | No | ||
137 | PEX16 | 4560044 | 14888 | -0.186 | -0.3683 | No | ||
138 | ARFGEF2 | 5550500 | 15044 | -0.203 | -0.3735 | No | ||
139 | GLTP | 3440603 | 15082 | -0.208 | -0.3723 | No | ||
140 | SLC25A5 | 1980672 | 15121 | -0.213 | -0.3711 | No | ||
141 | EEF1B2 | 4850400 6130161 | 15140 | -0.215 | -0.3687 | No | ||
142 | ZIC4 | 1500082 | 15230 | -0.226 | -0.3701 | No | ||
143 | LTB4R2 | 1990746 | 15390 | -0.249 | -0.3749 | No | ||
144 | PCBP4 | 6350722 | 15431 | -0.255 | -0.3731 | No | ||
145 | PRG4 | 5860156 6650086 | 15566 | -0.280 | -0.3760 | No | ||
146 | CBX7 | 3940035 | 15581 | -0.282 | -0.3724 | No | ||
147 | MARK2 | 7210608 | 15621 | -0.288 | -0.3701 | No | ||
148 | ASB7 | 520242 2450088 3990563 4280538 | 15762 | -0.313 | -0.3728 | No | ||
149 | FKBP5 | 2190048 | 16035 | -0.368 | -0.3819 | No | ||
150 | TOMM70A | 780114 | 16145 | -0.394 | -0.3817 | No | ||
151 | SLC25A1 | 4050402 | 16316 | -0.442 | -0.3841 | Yes | ||
152 | NET1 | 2900707 | 16374 | -0.460 | -0.3801 | Yes | ||
153 | PDLIM7 | 4780136 | 16387 | -0.462 | -0.3736 | Yes | ||
154 | COL15A1 | 6840113 | 16406 | -0.468 | -0.3674 | Yes | ||
155 | MOV10 | 50673 430577 3870280 | 16442 | -0.478 | -0.3619 | Yes | ||
156 | PELO | 3440706 | 16483 | -0.488 | -0.3565 | Yes | ||
157 | NR1H3 | 4810215 5570292 | 16500 | -0.491 | -0.3498 | Yes | ||
158 | RPS3A | 2470086 | 16504 | -0.492 | -0.3423 | Yes | ||
159 | PKP4 | 3710400 5890097 | 16600 | -0.526 | -0.3394 | Yes | ||
160 | AGPAT1 | 610056 | 16674 | -0.551 | -0.3348 | Yes | ||
161 | PDE3B | 2030563 | 16711 | -0.562 | -0.3281 | Yes | ||
162 | ADRB2 | 3290373 | 16860 | -0.609 | -0.3267 | Yes | ||
163 | PRKCSH | 3360398 | 16870 | -0.610 | -0.3177 | Yes | ||
164 | GMPPB | 4610538 | 16879 | -0.615 | -0.3087 | Yes | ||
165 | TMPIT | 3830538 | 16886 | -0.618 | -0.2994 | Yes | ||
166 | CLCN2 | 1940021 | 16946 | -0.640 | -0.2927 | Yes | ||
167 | NIPSNAP1 | 6860138 | 17091 | -0.701 | -0.2897 | Yes | ||
168 | NTNG2 | 1770438 6380408 | 17393 | -0.833 | -0.2932 | Yes | ||
169 | AP1B1 | 4290373 | 17427 | -0.849 | -0.2819 | Yes | ||
170 | TPI1 | 1500215 2100154 | 17555 | -0.922 | -0.2745 | Yes | ||
171 | LMAN2 | 430154 | 17653 | -0.976 | -0.2647 | Yes | ||
172 | RTN4 | 50725 630647 870097 870184 | 17730 | -1.005 | -0.2533 | Yes | ||
173 | PDE8A | 5080446 | 17757 | -1.021 | -0.2389 | Yes | ||
174 | LPL | 1450735 2970706 | 17760 | -1.023 | -0.2232 | Yes | ||
175 | BAZ2A | 730184 | 17764 | -1.024 | -0.2075 | Yes | ||
176 | PDZK1 | 2320128 | 17838 | -1.082 | -0.1948 | Yes | ||
177 | ETFDH | 4670358 | 17843 | -1.086 | -0.1782 | Yes | ||
178 | RASGRP2 | 2970333 | 17897 | -1.125 | -0.1637 | Yes | ||
179 | ZSWIM3 | 1230563 | 17932 | -1.148 | -0.1478 | Yes | ||
180 | SLC25A25 | 1230605 | 17968 | -1.178 | -0.1315 | Yes | ||
181 | SESN3 | 110687 | 18034 | -1.234 | -0.1159 | Yes | ||
182 | SLC26A6 | 4810575 | 18043 | -1.242 | -0.0972 | Yes | ||
183 | TP53 | 6130707 | 18184 | -1.390 | -0.0833 | Yes | ||
184 | GCH1 | 670364 6550358 | 18206 | -1.422 | -0.0624 | Yes | ||
185 | USP52 | 3710215 6380133 | 18224 | -1.453 | -0.0409 | Yes | ||
186 | TRAF4 | 3060041 4920528 6980286 | 18403 | -1.762 | -0.0233 | Yes | ||
187 | PAK4 | 1690152 | 18548 | -2.254 | 0.0037 | Yes |