Dataset | Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch_repos |
Phenotype | phenotype_absentNotch_versus_wtNotch.cls#absentNotch_versus_wtNotch_repos |
Upregulated in class | wtNotch |
GeneSet | V$ETS1_B |
Enrichment Score (ES) | -0.44584438 |
Normalized Enrichment Score (NES) | -1.3874933 |
Nominal p-value | 0.0046620048 |
FDR q-value | 1.0 |
FWER p-Value | 0.996 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PTK2 | 1780148 | 28 | 3.004 | 0.0336 | No | ||
2 | S100A10 | 6350010 | 71 | 2.418 | 0.0596 | No | ||
3 | IMPDH1 | 3190735 7050546 | 77 | 2.354 | 0.0868 | No | ||
4 | FOXP1 | 6510433 | 341 | 1.604 | 0.0913 | No | ||
5 | EXTL2 | 5050433 | 354 | 1.585 | 0.1092 | No | ||
6 | ABCG1 | 60692 | 487 | 1.423 | 0.1187 | No | ||
7 | LUC7L | 6040156 6110411 | 544 | 1.369 | 0.1316 | No | ||
8 | HSD3B7 | 1410129 | 588 | 1.320 | 0.1447 | No | ||
9 | PABPC1 | 2650180 2690253 6020632 1990270 | 819 | 1.149 | 0.1457 | No | ||
10 | NDUFS2 | 4850020 6200402 | 1131 | 0.970 | 0.1402 | No | ||
11 | ELMO1 | 110338 1190451 1580148 1850609 2350706 2370369 2450129 3840113 4150184 4280079 6290066 6380435 6770494 7100180 | 1133 | 0.970 | 0.1515 | No | ||
12 | SLC30A7 | 2230463 | 1349 | 0.848 | 0.1497 | No | ||
13 | AXUD1 | 1230053 | 1464 | 0.791 | 0.1528 | No | ||
14 | NME1 | 770014 | 1692 | 0.688 | 0.1485 | No | ||
15 | ETV6 | 610524 | 1750 | 0.666 | 0.1532 | No | ||
16 | MAP4K4 | 2360059 | 1787 | 0.647 | 0.1588 | No | ||
17 | ITPKB | 2900195 7100039 | 2100 | 0.533 | 0.1481 | No | ||
18 | DLGAP4 | 4570672 5690161 | 2175 | 0.506 | 0.1500 | No | ||
19 | CAP1 | 2650278 | 2472 | 0.417 | 0.1388 | No | ||
20 | RUVBL1 | 4280239 5080273 | 2638 | 0.376 | 0.1343 | No | ||
21 | HYAL2 | 1500152 | 2695 | 0.361 | 0.1354 | No | ||
22 | RPS3 | 1570017 2370170 | 2782 | 0.342 | 0.1348 | No | ||
23 | FYN | 2100468 4760520 4850687 | 2920 | 0.311 | 0.1310 | No | ||
24 | SLC4A1AP | 3190576 | 2926 | 0.308 | 0.1343 | No | ||
25 | RAP2C | 1690132 | 3024 | 0.288 | 0.1324 | No | ||
26 | SLC9A9 | 1940309 | 3112 | 0.273 | 0.1309 | No | ||
27 | BCL2L2 | 2760692 6770739 | 3126 | 0.271 | 0.1333 | No | ||
28 | CANX | 4760402 | 3220 | 0.252 | 0.1313 | No | ||
29 | CD79A | 3450563 | 3289 | 0.242 | 0.1304 | No | ||
30 | SPRED1 | 6940706 | 3357 | 0.231 | 0.1295 | No | ||
31 | LAG3 | 6860112 | 3472 | 0.215 | 0.1258 | No | ||
32 | DAB2IP | 3170064 6200441 | 3493 | 0.212 | 0.1272 | No | ||
33 | E2F3 | 50162 460180 | 3567 | 0.203 | 0.1256 | No | ||
34 | PDGFB | 3060440 6370008 | 3574 | 0.203 | 0.1276 | No | ||
35 | FURIN | 4120168 | 3599 | 0.199 | 0.1287 | No | ||
36 | NRG1 | 1050332 | 3718 | 0.187 | 0.1244 | No | ||
37 | PCDH7 | 450398 4150040 | 3734 | 0.185 | 0.1258 | No | ||
38 | ARHGAP15 | 610446 2340327 2900438 | 3746 | 0.183 | 0.1273 | No | ||
39 | CENTB1 | 2120093 | 4388 | 0.127 | 0.0940 | No | ||
40 | TNFSF11 | 6350204 | 4416 | 0.125 | 0.0941 | No | ||
41 | SLC7A1 | 2450193 2710241 | 4469 | 0.122 | 0.0927 | No | ||
42 | CNKSR1 | 730528 3390672 | 4509 | 0.119 | 0.0919 | No | ||
43 | DPPA4 | 6860692 6900164 | 4537 | 0.118 | 0.0919 | No | ||
44 | KLF12 | 1660095 4810288 5340546 6520286 | 4562 | 0.117 | 0.0919 | No | ||
45 | ETF1 | 6770075 | 4737 | 0.106 | 0.0837 | No | ||
46 | GPR120 | 2350398 | 5039 | 0.091 | 0.0685 | No | ||
47 | EPN3 | 2350592 | 5079 | 0.090 | 0.0674 | No | ||
48 | GLP2R | 4150577 5290273 7050095 | 5083 | 0.090 | 0.0683 | No | ||
49 | KCND1 | 6860278 | 5095 | 0.089 | 0.0687 | No | ||
50 | MMP3 | 2650368 2970056 | 5321 | 0.080 | 0.0575 | No | ||
51 | DLC1 | 1090632 6450594 | 5658 | 0.069 | 0.0400 | No | ||
52 | SLC39A11 | 5860687 | 5702 | 0.067 | 0.0385 | No | ||
53 | ITGA11 | 1740112 6590110 | 5709 | 0.067 | 0.0389 | No | ||
54 | CSF2 | 1660593 | 5781 | 0.065 | 0.0358 | No | ||
55 | SNCAIP | 4010551 | 5796 | 0.064 | 0.0358 | No | ||
56 | STARD13 | 540722 | 5856 | 0.063 | 0.0334 | No | ||
57 | KLF13 | 4670563 | 5870 | 0.062 | 0.0334 | No | ||
58 | LIF | 1410373 2060129 3990338 | 6070 | 0.056 | 0.0233 | No | ||
59 | HOXA1 | 1190524 5420142 | 6140 | 0.055 | 0.0202 | No | ||
60 | SHC3 | 2690398 | 6209 | 0.053 | 0.0171 | No | ||
61 | ELK3 | 460377 1400762 3710497 | 6492 | 0.046 | 0.0023 | No | ||
62 | LRRN3 | 1450133 | 6510 | 0.046 | 0.0020 | No | ||
63 | LOXL3 | 4010168 | 6519 | 0.046 | 0.0021 | No | ||
64 | RASA2 | 7100706 | 6534 | 0.045 | 0.0018 | No | ||
65 | NEDD4 | 460736 1190280 | 6875 | 0.039 | -0.0162 | No | ||
66 | PTPN11 | 2230100 2470180 6100528 | 7089 | 0.034 | -0.0273 | No | ||
67 | APBA1 | 3140487 | 7278 | 0.031 | -0.0371 | No | ||
68 | MLLT7 | 4480707 | 7427 | 0.029 | -0.0448 | No | ||
69 | CRADD | 6770520 | 7539 | 0.027 | -0.0506 | No | ||
70 | KIF1C | 2480484 | 7835 | 0.022 | -0.0663 | No | ||
71 | TIMP4 | 6110433 | 7878 | 0.021 | -0.0683 | No | ||
72 | PAX6 | 1190025 | 7921 | 0.021 | -0.0704 | No | ||
73 | TWIST1 | 5130619 | 8583 | 0.011 | -0.1061 | No | ||
74 | MYH10 | 2640673 | 8745 | 0.008 | -0.1147 | No | ||
75 | CHES1 | 4570121 5700162 | 8849 | 0.007 | -0.1202 | No | ||
76 | CPNE8 | 7040039 | 8881 | 0.007 | -0.1218 | No | ||
77 | RHOV | 5860100 | 9405 | -0.001 | -0.1502 | No | ||
78 | TENC1 | 1980403 7050575 | 9817 | -0.006 | -0.1724 | No | ||
79 | IL1RAPL2 | 1940075 | 9878 | -0.007 | -0.1756 | No | ||
80 | FOSL1 | 430021 | 9950 | -0.008 | -0.1793 | No | ||
81 | DHH | 2120433 | 10142 | -0.011 | -0.1896 | No | ||
82 | ZNF205 | 6900022 | 10257 | -0.012 | -0.1956 | No | ||
83 | ZNF35 | 670156 | 10327 | -0.014 | -0.1992 | No | ||
84 | IL13 | 7040021 | 10422 | -0.015 | -0.2041 | No | ||
85 | E2F5 | 5860575 | 10576 | -0.017 | -0.2122 | No | ||
86 | LCP2 | 2680066 6650707 | 10878 | -0.022 | -0.2283 | No | ||
87 | PML | 50093 2190435 2450402 3840082 | 10965 | -0.024 | -0.2327 | No | ||
88 | UBTF | 4210450 6840403 | 11033 | -0.025 | -0.2360 | No | ||
89 | TYRO3 | 3130193 | 11091 | -0.026 | -0.2388 | No | ||
90 | DKK2 | 3610433 | 11118 | -0.026 | -0.2399 | No | ||
91 | ADAM15 | 5890707 | 11305 | -0.029 | -0.2497 | No | ||
92 | AMD1 | 6290128 | 11467 | -0.032 | -0.2580 | No | ||
93 | DOK1 | 1050279 2680112 5220273 | 11547 | -0.034 | -0.2619 | No | ||
94 | SOST | 1170195 | 11717 | -0.037 | -0.2706 | No | ||
95 | ITPR2 | 5360128 | 11794 | -0.039 | -0.2743 | No | ||
96 | IL12B | 460008 | 12044 | -0.044 | -0.2873 | No | ||
97 | HOXA10 | 6110397 7100458 | 12108 | -0.045 | -0.2902 | No | ||
98 | GJA5 | 60142 1740008 1740026 | 12198 | -0.047 | -0.2945 | No | ||
99 | PLCB2 | 360132 | 12232 | -0.048 | -0.2957 | No | ||
100 | GPR150 | 2570440 | 12359 | -0.051 | -0.3019 | No | ||
101 | FLNC | 2360048 5050270 | 12481 | -0.055 | -0.3079 | No | ||
102 | RNF12 | 6860717 | 12512 | -0.055 | -0.3088 | No | ||
103 | LYN | 6040600 | 12550 | -0.056 | -0.3102 | No | ||
104 | KCNQ1 | 1580050 6860441 | 12713 | -0.061 | -0.3183 | No | ||
105 | ADAMTS4 | 430435 | 12800 | -0.063 | -0.3222 | No | ||
106 | CAST | 3850082 5420671 6200156 | 12867 | -0.065 | -0.3250 | No | ||
107 | BMP4 | 380113 | 12965 | -0.069 | -0.3295 | No | ||
108 | HOXC4 | 1940193 | 13066 | -0.073 | -0.3340 | No | ||
109 | POU3F4 | 870274 | 13169 | -0.077 | -0.3387 | No | ||
110 | OLFM1 | 3360161 5570066 | 13201 | -0.078 | -0.3394 | No | ||
111 | SEC24C | 6980707 | 13218 | -0.078 | -0.3394 | No | ||
112 | UBE2R2 | 1230504 | 13291 | -0.081 | -0.3424 | No | ||
113 | STK16 | 1740154 | 13572 | -0.093 | -0.3565 | No | ||
114 | SLC12A4 | 130731 | 13923 | -0.112 | -0.3741 | No | ||
115 | BDKRB2 | 4780706 | 13932 | -0.113 | -0.3732 | No | ||
116 | GMPR2 | 4920204 | 13989 | -0.115 | -0.3749 | No | ||
117 | MADD | 6100725 7000088 | 14350 | -0.139 | -0.3928 | No | ||
118 | TBN | 3290270 | 14516 | -0.152 | -0.4000 | No | ||
119 | VPS39 | 50332 | 14518 | -0.152 | -0.3983 | No | ||
120 | SLC16A2 | 6660739 | 14613 | -0.161 | -0.4015 | No | ||
121 | SEMA4C | 1980315 | 14668 | -0.166 | -0.4025 | No | ||
122 | STK10 | 2760010 3940605 | 14716 | -0.170 | -0.4031 | No | ||
123 | MTPN | 3940167 | 14772 | -0.176 | -0.4040 | No | ||
124 | HM13 | 60463 940711 4850609 | 14927 | -0.190 | -0.4101 | No | ||
125 | CACNA1D | 1740315 4730731 | 14960 | -0.194 | -0.4096 | No | ||
126 | RGS14 | 380086 | 15099 | -0.210 | -0.4146 | No | ||
127 | NT5C2 | 4280735 4670528 | 15283 | -0.234 | -0.4218 | No | ||
128 | DPP3 | 2680725 3780670 | 15432 | -0.255 | -0.4269 | No | ||
129 | SPRED2 | 510138 540195 | 15466 | -0.261 | -0.4256 | No | ||
130 | GALNT2 | 2260279 4060239 | 15495 | -0.268 | -0.4240 | No | ||
131 | CBLB | 3520465 4670348 | 15504 | -0.269 | -0.4213 | No | ||
132 | ORC4L | 4230538 5550288 | 15761 | -0.313 | -0.4315 | No | ||
133 | MAP4K2 | 4200037 | 15850 | -0.331 | -0.4324 | No | ||
134 | LCK | 3360142 | 15886 | -0.337 | -0.4303 | No | ||
135 | ARPP-19 | 5700025 | 15945 | -0.350 | -0.4294 | No | ||
136 | TGFB3 | 1070041 | 16150 | -0.396 | -0.4358 | No | ||
137 | ESM1 | 1410594 | 16287 | -0.434 | -0.4381 | No | ||
138 | LYL1 | 2900242 | 16430 | -0.476 | -0.4403 | Yes | ||
139 | ADAM11 | 1050008 3130494 | 16476 | -0.486 | -0.4370 | Yes | ||
140 | IKBKB | 6840072 | 16623 | -0.532 | -0.4387 | Yes | ||
141 | MAGED1 | 6650332 | 16703 | -0.561 | -0.4365 | Yes | ||
142 | SLC9A3R1 | 6020373 | 16735 | -0.568 | -0.4315 | Yes | ||
143 | PIK3CG | 5890110 | 16793 | -0.589 | -0.4277 | Yes | ||
144 | RGS3 | 60670 540736 1340180 1500369 3390735 4010131 4610402 6380114 | 16834 | -0.602 | -0.4228 | Yes | ||
145 | GTF2B | 6860685 | 16846 | -0.604 | -0.4164 | Yes | ||
146 | TGIF2 | 3840364 4050520 | 16978 | -0.655 | -0.4158 | Yes | ||
147 | CAMK1D | 1660100 2350309 | 17007 | -0.667 | -0.4095 | Yes | ||
148 | ELOVL6 | 5340746 | 17089 | -0.700 | -0.4058 | Yes | ||
149 | BIN3 | 380551 | 17090 | -0.700 | -0.3976 | Yes | ||
150 | NEDD8 | 2350722 | 17168 | -0.733 | -0.3932 | Yes | ||
151 | ROD1 | 2060324 3140332 | 17174 | -0.735 | -0.3849 | Yes | ||
152 | RGMA | 2450711 | 17201 | -0.749 | -0.3775 | Yes | ||
153 | SEPT1 | 3290546 | 17314 | -0.793 | -0.3743 | Yes | ||
154 | SH3BGRL | 2060110 | 17378 | -0.822 | -0.3681 | Yes | ||
155 | ITPR3 | 4010632 | 17463 | -0.873 | -0.3625 | Yes | ||
156 | CORO1A | 3140609 3190020 3190037 | 17468 | -0.875 | -0.3525 | Yes | ||
157 | SRPR | 6590647 6370114 | 17542 | -0.917 | -0.3457 | Yes | ||
158 | HIC1 | 2650142 | 17635 | -0.963 | -0.3394 | Yes | ||
159 | TNNI2 | 5910739 | 17636 | -0.963 | -0.3282 | Yes | ||
160 | DMTF1 | 5910047 1570497 2480100 6620239 | 17700 | -0.998 | -0.3199 | Yes | ||
161 | HNRPK | 1190348 2060411 2570092 6840551 | 17722 | -1.002 | -0.3094 | Yes | ||
162 | BAZ2A | 730184 | 17764 | -1.024 | -0.2996 | Yes | ||
163 | POLD4 | 2320082 | 17766 | -1.024 | -0.2877 | Yes | ||
164 | JUNB | 4230048 | 17821 | -1.073 | -0.2781 | Yes | ||
165 | ROCK1 | 130044 | 17902 | -1.127 | -0.2693 | Yes | ||
166 | KCNAB2 | 4850315 | 17944 | -1.160 | -0.2579 | Yes | ||
167 | PSME2 | 4850086 | 17947 | -1.162 | -0.2444 | Yes | ||
168 | TPP2 | 3850093 | 17985 | -1.190 | -0.2325 | Yes | ||
169 | TRIM41 | 4070019 6110670 | 18007 | -1.207 | -0.2196 | Yes | ||
170 | PPP1R9B | 3130619 | 18031 | -1.227 | -0.2065 | Yes | ||
171 | RNF40 | 3610397 | 18108 | -1.306 | -0.1953 | Yes | ||
172 | RNF31 | 110035 | 18284 | -1.543 | -0.1868 | Yes | ||
173 | DEF6 | 840593 | 18292 | -1.555 | -0.1690 | Yes | ||
174 | LCP1 | 4280397 | 18306 | -1.578 | -0.1512 | Yes | ||
175 | HMGA1 | 6580408 | 18323 | -1.609 | -0.1333 | Yes | ||
176 | UBE2L3 | 1690707 5900242 | 18394 | -1.745 | -0.1167 | Yes | ||
177 | FBXO36 | 1410086 | 18460 | -1.921 | -0.0978 | Yes | ||
178 | PDLIM2 | 2450603 2810551 3830040 4670164 | 18495 | -2.043 | -0.0757 | Yes | ||
179 | GIT2 | 6040039 6770181 | 18509 | -2.094 | -0.0520 | Yes | ||
180 | POU2AF1 | 5690242 | 18615 | -4.937 | 0.0001 | Yes |