Dataset | Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch_repos |
Phenotype | phenotype_absentNotch_versus_wtNotch.cls#absentNotch_versus_wtNotch_repos |
Upregulated in class | absentNotch |
GeneSet | V$E2F_Q4 |
Enrichment Score (ES) | 0.50991875 |
Normalized Enrichment Score (NES) | 1.5156575 |
Nominal p-value | 0.0 |
FDR q-value | 0.17964333 |
FWER p-Value | 0.856 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | TMPO | 4050494 | 39 | 2.767 | 0.0359 | Yes | ||
2 | SOAT1 | 1190019 | 126 | 2.177 | 0.0612 | Yes | ||
3 | PPM1D | 1690193 | 156 | 2.052 | 0.0879 | Yes | ||
4 | DCK | 6900411 | 181 | 1.963 | 0.1136 | Yes | ||
5 | UGCGL1 | 4230072 | 231 | 1.856 | 0.1364 | Yes | ||
6 | GSPT1 | 5420050 | 240 | 1.825 | 0.1611 | Yes | ||
7 | AP4M1 | 70609 3440128 | 325 | 1.638 | 0.1791 | Yes | ||
8 | E2F1 | 5360093 | 394 | 1.543 | 0.1966 | Yes | ||
9 | ZCCHC8 | 2260332 2350487 | 531 | 1.377 | 0.2082 | Yes | ||
10 | STMN1 | 1990717 | 548 | 1.364 | 0.2261 | Yes | ||
11 | SFRS1 | 2360440 | 606 | 1.309 | 0.2410 | Yes | ||
12 | ALDH6A1 | 1770746 | 673 | 1.249 | 0.2546 | Yes | ||
13 | NASP | 2260139 2940369 5130707 | 754 | 1.193 | 0.2667 | Yes | ||
14 | IL4I1 | 3190161 | 763 | 1.188 | 0.2826 | Yes | ||
15 | HTF9C | 3190048 4120132 | 764 | 1.188 | 0.2989 | Yes | ||
16 | PHC1 | 520195 | 771 | 1.184 | 0.3149 | Yes | ||
17 | CDC25A | 3800184 | 844 | 1.122 | 0.3264 | Yes | ||
18 | RBL1 | 3130372 | 913 | 1.074 | 0.3375 | Yes | ||
19 | CTCF | 5340017 | 920 | 1.070 | 0.3519 | Yes | ||
20 | POLD3 | 6400278 | 925 | 1.066 | 0.3663 | Yes | ||
21 | NUP62 | 1240128 | 1023 | 1.009 | 0.3749 | Yes | ||
22 | FANCD2 | 1850280 6840348 | 1036 | 1.003 | 0.3881 | Yes | ||
23 | SFRS2 | 50707 380593 | 1090 | 0.992 | 0.3989 | Yes | ||
24 | POLE4 | 6860097 | 1188 | 0.944 | 0.4066 | Yes | ||
25 | H2AFZ | 1470168 | 1287 | 0.879 | 0.4134 | Yes | ||
26 | KPNB1 | 1690138 | 1386 | 0.833 | 0.4195 | Yes | ||
27 | PCNA | 940754 | 1413 | 0.821 | 0.4294 | Yes | ||
28 | CDCA7 | 3060097 | 1461 | 0.793 | 0.4378 | Yes | ||
29 | MSH2 | 6180273 | 1472 | 0.787 | 0.4480 | Yes | ||
30 | ACO2 | 4230600 | 1493 | 0.778 | 0.4576 | Yes | ||
31 | MCM3 | 5570068 | 1651 | 0.703 | 0.4588 | Yes | ||
32 | UNG | 3130110 6100364 | 1740 | 0.670 | 0.4633 | Yes | ||
33 | SLCO3A1 | 1050408 2370156 6110072 | 1848 | 0.624 | 0.4660 | Yes | ||
34 | PIM1 | 630047 | 1855 | 0.621 | 0.4743 | Yes | ||
35 | MCM4 | 2760673 5420711 | 1904 | 0.605 | 0.4800 | Yes | ||
36 | AK2 | 4590458 4760195 6110097 | 2066 | 0.545 | 0.4787 | Yes | ||
37 | RAB11B | 3990609 | 2072 | 0.544 | 0.4860 | Yes | ||
38 | PPP1R8 | 6290292 | 2083 | 0.540 | 0.4928 | Yes | ||
39 | MRPL40 | 2370215 | 2144 | 0.515 | 0.4967 | Yes | ||
40 | SLC38A1 | 520465 | 2192 | 0.502 | 0.5010 | Yes | ||
41 | NOLC1 | 2350195 | 2219 | 0.494 | 0.5064 | Yes | ||
42 | PPP1CC | 6380300 2510647 | 2277 | 0.479 | 0.5099 | Yes | ||
43 | MCM6 | 60092 540181 6510110 | 2587 | 0.390 | 0.4985 | No | ||
44 | MCM2 | 5050139 | 2607 | 0.385 | 0.5028 | No | ||
45 | EPC1 | 1570050 5290095 6900193 | 2623 | 0.380 | 0.5072 | No | ||
46 | BRMS1L | 6110609 | 2766 | 0.345 | 0.5043 | No | ||
47 | ATAD2 | 870242 2260687 | 2821 | 0.334 | 0.5059 | No | ||
48 | POLA2 | 940519 | 2929 | 0.308 | 0.5044 | No | ||
49 | HIST1H2AH | 3710333 | 2951 | 0.303 | 0.5074 | No | ||
50 | EZH2 | 6130605 6380524 | 3159 | 0.264 | 0.4998 | No | ||
51 | HIRA | 4480609 5270167 | 3217 | 0.252 | 0.5002 | No | ||
52 | JPH1 | 610739 | 3296 | 0.240 | 0.4993 | No | ||
53 | EFNA5 | 460707 2190519 | 3409 | 0.225 | 0.4963 | No | ||
54 | USP37 | 2470433 | 3488 | 0.212 | 0.4950 | No | ||
55 | EED | 2320373 | 3557 | 0.204 | 0.4941 | No | ||
56 | E2F3 | 50162 460180 | 3567 | 0.203 | 0.4964 | No | ||
57 | UFD1L | 870020 | 3686 | 0.191 | 0.4927 | No | ||
58 | KCNA6 | 450291 1400086 1660291 2470576 | 3810 | 0.174 | 0.4884 | No | ||
59 | SLC6A4 | 2230372 | 3868 | 0.169 | 0.4876 | No | ||
60 | ADAMTS2 | 2650025 6370133 6840670 | 3869 | 0.169 | 0.4900 | No | ||
61 | PRKDC | 1400072 4230541 | 3975 | 0.161 | 0.4865 | No | ||
62 | SNRPD1 | 4480162 | 4206 | 0.140 | 0.4759 | No | ||
63 | RQCD1 | 1850139 | 4334 | 0.131 | 0.4709 | No | ||
64 | HNRPUL1 | 2120008 4920408 5570180 6370609 6770403 | 4488 | 0.121 | 0.4643 | No | ||
65 | WEE1 | 3390070 | 4707 | 0.107 | 0.4539 | No | ||
66 | PVRL1 | 2570167 5220519 5890500 3190309 | 4817 | 0.101 | 0.4494 | No | ||
67 | UXT | 110019 5080066 | 5042 | 0.091 | 0.4385 | No | ||
68 | PCSK1 | 2350148 | 5212 | 0.085 | 0.4306 | No | ||
69 | STAG1 | 1190300 1400722 4590100 | 5258 | 0.083 | 0.4293 | No | ||
70 | PAQR4 | 730736 | 5428 | 0.076 | 0.4212 | No | ||
71 | SMAD6 | 870504 | 5437 | 0.076 | 0.4218 | No | ||
72 | DMD | 1740041 3990332 | 5875 | 0.062 | 0.3989 | No | ||
73 | FMO4 | 360735 | 5909 | 0.061 | 0.3980 | No | ||
74 | CLSPN | 2190239 2630687 5550632 | 6311 | 0.051 | 0.3770 | No | ||
75 | SP3 | 3840338 | 6387 | 0.049 | 0.3736 | No | ||
76 | ASXL2 | 130670 | 6440 | 0.048 | 0.3714 | No | ||
77 | E2F7 | 4200056 | 6467 | 0.047 | 0.3707 | No | ||
78 | CHD2 | 4070039 | 6889 | 0.038 | 0.3484 | No | ||
79 | YBX2 | 3520441 | 7144 | 0.033 | 0.3351 | No | ||
80 | HOXC10 | 5360170 | 7178 | 0.033 | 0.3338 | No | ||
81 | MCM8 | 6130743 | 7491 | 0.027 | 0.3172 | No | ||
82 | ACBD6 | 4200446 | 7686 | 0.024 | 0.3071 | No | ||
83 | PAX6 | 1190025 | 7921 | 0.021 | 0.2947 | No | ||
84 | GABRB3 | 4150164 | 8047 | 0.019 | 0.2882 | No | ||
85 | RHD | 4050168 | 8129 | 0.018 | 0.2840 | No | ||
86 | CBX5 | 3830072 6290167 | 8613 | 0.010 | 0.2580 | No | ||
87 | PODN | 3710068 | 8644 | 0.010 | 0.2565 | No | ||
88 | MYH10 | 2640673 | 8745 | 0.008 | 0.2512 | No | ||
89 | ARHGAP6 | 2060121 | 8804 | 0.008 | 0.2482 | No | ||
90 | WNT3 | 2360685 | 9218 | 0.002 | 0.2258 | No | ||
91 | DNAJC9 | 6130019 | 9268 | 0.001 | 0.2232 | No | ||
92 | MCM7 | 3290292 5220056 | 9304 | 0.001 | 0.2213 | No | ||
93 | CASP8AP2 | 5910593 | 9488 | -0.002 | 0.2114 | No | ||
94 | ZBTB4 | 6450441 | 9543 | -0.002 | 0.2085 | No | ||
95 | ABI2 | 940368 4200092 | 9899 | -0.007 | 0.1894 | No | ||
96 | IPO7 | 2190746 | 9935 | -0.008 | 0.1876 | No | ||
97 | ILF3 | 940722 3190647 6520110 | 9953 | -0.008 | 0.1868 | No | ||
98 | POLE2 | 6110041 | 10004 | -0.009 | 0.1842 | No | ||
99 | EPHB1 | 4610056 | 10322 | -0.014 | 0.1672 | No | ||
100 | NELL2 | 2340725 4280301 5420008 | 10337 | -0.014 | 0.1667 | No | ||
101 | CRK | 1230162 4780128 | 10536 | -0.017 | 0.1562 | No | ||
102 | HNRPD | 4120021 | 10669 | -0.019 | 0.1493 | No | ||
103 | TYRO3 | 3130193 | 11091 | -0.026 | 0.1268 | No | ||
104 | NUP153 | 7000452 | 11592 | -0.035 | 0.1002 | No | ||
105 | GRIA4 | 2640131 | 11683 | -0.037 | 0.0959 | No | ||
106 | STK35 | 2360121 | 11781 | -0.038 | 0.0911 | No | ||
107 | TREX2 | 4920707 | 12048 | -0.044 | 0.0773 | No | ||
108 | TOPBP1 | 6020333 | 12075 | -0.044 | 0.0765 | No | ||
109 | INSM1 | 3450671 | 12196 | -0.047 | 0.0707 | No | ||
110 | PHF15 | 6550066 6860673 | 12753 | -0.062 | 0.0414 | No | ||
111 | GMNN | 2630148 | 13220 | -0.078 | 0.0173 | No | ||
112 | FBXO5 | 2630551 | 13457 | -0.088 | 0.0057 | No | ||
113 | HS6ST3 | 5910138 | 13472 | -0.089 | 0.0061 | No | ||
114 | NRP2 | 4070400 5860041 6650446 | 13477 | -0.089 | 0.0071 | No | ||
115 | HNRPR | 2320440 2900601 4610008 | 13599 | -0.094 | 0.0019 | No | ||
116 | CCNT1 | 2450563 5390184 | 14069 | -0.120 | -0.0219 | No | ||
117 | CDC6 | 4570296 5360600 | 14080 | -0.120 | -0.0208 | No | ||
118 | ING3 | 110438 2060390 | 14093 | -0.121 | -0.0197 | No | ||
119 | CORT | 360008 2340092 | 14138 | -0.124 | -0.0204 | No | ||
120 | GPRC5B | 2760114 | 14692 | -0.168 | -0.0481 | No | ||
121 | MXD3 | 6220014 | 14757 | -0.174 | -0.0491 | No | ||
122 | KCND2 | 1170128 2100112 | 14837 | -0.182 | -0.0509 | No | ||
123 | HNRPA1 | 4670398 5050687 | 14863 | -0.184 | -0.0497 | No | ||
124 | NCL | 2360463 4540279 | 14934 | -0.191 | -0.0509 | No | ||
125 | FHOD1 | 2680279 | 15011 | -0.199 | -0.0523 | No | ||
126 | SEMA5A | 6200110 6520435 | 15187 | -0.221 | -0.0587 | No | ||
127 | STAG2 | 4540132 | 15364 | -0.245 | -0.0649 | No | ||
128 | ARID4A | 520156 1050707 | 15524 | -0.274 | -0.0697 | No | ||
129 | RAD51 | 6110450 6980280 | 15572 | -0.281 | -0.0684 | No | ||
130 | TBX6 | 4730139 6840647 | 15933 | -0.346 | -0.0831 | No | ||
131 | HCN3 | 3940438 6840750 | 16075 | -0.377 | -0.0856 | No | ||
132 | CDC45L | 70537 3130114 | 16078 | -0.378 | -0.0805 | No | ||
133 | SUMO1 | 1990364 2760338 6380195 | 16142 | -0.393 | -0.0785 | No | ||
134 | POLR2A | 5220647 | 16148 | -0.395 | -0.0733 | No | ||
135 | ERBB2IP | 580253 1090672 | 16238 | -0.419 | -0.0724 | No | ||
136 | MAZ | 3360121 6940750 | 16251 | -0.423 | -0.0672 | No | ||
137 | DDB2 | 3520341 4610168 4850184 4920717 | 16363 | -0.458 | -0.0670 | No | ||
138 | SFRS7 | 2760408 | 16381 | -0.461 | -0.0615 | No | ||
139 | HIST1H2BK | 6130433 | 16424 | -0.474 | -0.0573 | No | ||
140 | RPS6KA5 | 2120563 7040546 | 16466 | -0.485 | -0.0528 | No | ||
141 | PRPS1 | 6350129 | 16555 | -0.513 | -0.0506 | No | ||
142 | RANBP1 | 430215 1090180 | 16580 | -0.519 | -0.0447 | No | ||
143 | PHF13 | 450435 | 16748 | -0.572 | -0.0459 | No | ||
144 | PHF5A | 2690519 | 16856 | -0.607 | -0.0433 | No | ||
145 | POLD1 | 4830026 | 16949 | -0.641 | -0.0395 | No | ||
146 | DNAJC11 | 360465 3390215 | 17127 | -0.719 | -0.0392 | No | ||
147 | SYNGR4 | 6520450 | 17200 | -0.749 | -0.0328 | No | ||
148 | CDT1 | 3780682 | 17231 | -0.761 | -0.0240 | No | ||
149 | DNMT1 | 2260097 | 17312 | -0.791 | -0.0174 | No | ||
150 | SFRS10 | 6130528 6400438 7040112 | 17789 | -1.047 | -0.0288 | No | ||
151 | HMGN2 | 3140091 | 17854 | -1.096 | -0.0172 | No | ||
152 | ATF5 | 5670685 | 18029 | -1.226 | -0.0098 | No | ||
153 | USP52 | 3710215 6380133 | 18224 | -1.453 | -0.0003 | No | ||
154 | RRM2 | 6350059 6940162 | 18298 | -1.562 | 0.0172 | No |