Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch_repos |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos |
Upregulated in class | truncNotch |
GeneSet | V$AP1_Q6 |
Enrichment Score (ES) | -0.4246317 |
Normalized Enrichment Score (NES) | -1.2325579 |
Nominal p-value | 0.056013178 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PPP2CA | 3990113 | 115 | 4.067 | 0.0233 | No | ||
2 | TRIM8 | 6130441 | 453 | 2.806 | 0.0254 | No | ||
3 | ATP1B1 | 3130594 | 478 | 2.762 | 0.0442 | No | ||
4 | XPOT | 7050184 | 553 | 2.580 | 0.0590 | No | ||
5 | ICK | 1580746 3140021 | 568 | 2.543 | 0.0767 | No | ||
6 | NR1D1 | 2360471 770746 6590204 | 602 | 2.480 | 0.0929 | No | ||
7 | CYFIP1 | 5690082 | 664 | 2.374 | 0.1069 | No | ||
8 | PSMD7 | 2030619 6220594 | 697 | 2.328 | 0.1221 | No | ||
9 | NEFH | 630239 | 1061 | 1.821 | 0.1156 | No | ||
10 | PDAP1 | 1410735 | 1100 | 1.779 | 0.1265 | No | ||
11 | PSMD12 | 730044 | 1178 | 1.690 | 0.1346 | No | ||
12 | TCF12 | 3610324 7000156 | 1276 | 1.578 | 0.1408 | No | ||
13 | RBBP7 | 430113 450450 2370309 | 1507 | 1.334 | 0.1380 | No | ||
14 | YWHAZ | 1230717 | 1558 | 1.283 | 0.1446 | No | ||
15 | BTK | 3130044 | 1814 | 1.068 | 0.1385 | No | ||
16 | WNT6 | 4570364 | 1838 | 1.055 | 0.1450 | No | ||
17 | SLC16A6 | 1690156 | 1865 | 1.035 | 0.1511 | No | ||
18 | TRAF3 | 5690647 | 2043 | 0.943 | 0.1483 | No | ||
19 | LAMC1 | 4730025 | 2095 | 0.908 | 0.1522 | No | ||
20 | POLR3E | 380152 | 2169 | 0.869 | 0.1545 | No | ||
21 | PKN3 | 2260538 | 2249 | 0.816 | 0.1562 | No | ||
22 | GTF2B | 6860685 | 2263 | 0.810 | 0.1613 | No | ||
23 | APOBEC1 | 4610022 | 2287 | 0.801 | 0.1659 | No | ||
24 | GPX1 | 4150093 | 2345 | 0.768 | 0.1684 | No | ||
25 | CMAS | 2190129 | 2480 | 0.688 | 0.1661 | No | ||
26 | RIN1 | 510593 | 2853 | 0.520 | 0.1497 | No | ||
27 | PSMD4 | 430068 | 2925 | 0.488 | 0.1494 | No | ||
28 | ABI3 | 1740563 | 3038 | 0.448 | 0.1466 | No | ||
29 | SCOC | 610048 2230053 | 3099 | 0.427 | 0.1465 | No | ||
30 | MCART1 | 5270059 | 3180 | 0.397 | 0.1450 | No | ||
31 | LRRFIP2 | 670575 730152 6590438 | 3289 | 0.359 | 0.1418 | No | ||
32 | LTBP3 | 1190162 2650440 6520451 | 3298 | 0.354 | 0.1439 | No | ||
33 | VDR | 130156 510438 | 3329 | 0.348 | 0.1448 | No | ||
34 | PEA15 | 4590685 | 3440 | 0.313 | 0.1411 | No | ||
35 | ROCK2 | 1780035 5720025 | 3498 | 0.295 | 0.1402 | No | ||
36 | CASK | 2340215 3290576 6770215 | 3581 | 0.271 | 0.1377 | No | ||
37 | EIF4E | 1580403 70133 6380215 | 3604 | 0.264 | 0.1384 | No | ||
38 | APBA2BP | 5700341 | 3619 | 0.259 | 0.1395 | No | ||
39 | CDKN1A | 4050088 6400706 | 3730 | 0.231 | 0.1353 | No | ||
40 | NEK6 | 3360687 | 3818 | 0.213 | 0.1321 | No | ||
41 | COL27A1 | 1740390 | 3864 | 0.205 | 0.1311 | No | ||
42 | PITPNC1 | 3990017 | 3868 | 0.205 | 0.1325 | No | ||
43 | LAMA3 | 1190131 5290239 | 3969 | 0.184 | 0.1284 | No | ||
44 | DTNA | 1340600 1780731 2340278 2850132 | 4019 | 0.174 | 0.1270 | No | ||
45 | LAPTM5 | 5550372 | 4030 | 0.172 | 0.1277 | No | ||
46 | IDS | 360619 5720161 | 4151 | 0.153 | 0.1223 | No | ||
47 | IBRDC2 | 5130041 | 4167 | 0.152 | 0.1226 | No | ||
48 | PTP4A1 | 130692 | 4343 | 0.130 | 0.1140 | No | ||
49 | PCDH9 | 2100136 | 4371 | 0.126 | 0.1135 | No | ||
50 | NFATC4 | 2470735 | 4557 | 0.108 | 0.1042 | No | ||
51 | MARK1 | 450484 | 4561 | 0.108 | 0.1049 | No | ||
52 | KCNA2 | 5080403 | 4589 | 0.105 | 0.1042 | No | ||
53 | LAMC2 | 450692 2680041 4200059 4670148 | 4629 | 0.102 | 0.1028 | No | ||
54 | PFTK1 | 1780181 | 4849 | 0.086 | 0.0915 | No | ||
55 | SLC26A1 | 2190142 | 5043 | 0.075 | 0.0816 | No | ||
56 | DSCR1L1 | 940438 | 5182 | 0.067 | 0.0746 | No | ||
57 | GNAI1 | 4560390 | 5227 | 0.065 | 0.0727 | No | ||
58 | SPARC | 1690086 | 5355 | 0.060 | 0.0662 | No | ||
59 | SNCB | 3360133 | 5427 | 0.057 | 0.0628 | No | ||
60 | XLKD1 | 520441 | 5562 | 0.053 | 0.0559 | No | ||
61 | PTPRN | 5900577 | 5725 | 0.048 | 0.0475 | No | ||
62 | PLCD1 | 2030484 | 5822 | 0.044 | 0.0426 | No | ||
63 | HOXD3 | 6450154 | 6348 | 0.030 | 0.0143 | No | ||
64 | FAP | 4560019 | 6354 | 0.030 | 0.0143 | No | ||
65 | OMG | 6760066 | 6670 | 0.023 | -0.0026 | No | ||
66 | UCN2 | 4590372 | 6699 | 0.023 | -0.0040 | No | ||
67 | SLC35E4 | 2370711 | 6806 | 0.020 | -0.0096 | No | ||
68 | USP13 | 1450670 | 6819 | 0.020 | -0.0101 | No | ||
69 | IL9 | 3440338 | 7451 | 0.008 | -0.0443 | No | ||
70 | DSTN | 3140592 | 7472 | 0.008 | -0.0453 | No | ||
71 | EFNA1 | 3840672 | 7533 | 0.007 | -0.0485 | No | ||
72 | TRPV3 | 540341 | 7659 | 0.005 | -0.0553 | No | ||
73 | PHLDA2 | 4810494 | 8009 | -0.001 | -0.0742 | No | ||
74 | IL1RN | 2370333 | 8021 | -0.001 | -0.0748 | No | ||
75 | AP2B1 | 1450184 2370148 3520139 4850593 | 8111 | -0.003 | -0.0796 | No | ||
76 | SHC3 | 2690398 | 8135 | -0.003 | -0.0808 | No | ||
77 | CRYBA2 | 5900138 | 8164 | -0.003 | -0.0823 | No | ||
78 | HOXA11 | 6980133 | 8363 | -0.007 | -0.0930 | No | ||
79 | UCHL3 | 1240735 | 8697 | -0.012 | -0.1110 | No | ||
80 | SYT2 | 60609 | 8773 | -0.014 | -0.1149 | No | ||
81 | FBXW11 | 6450632 | 8838 | -0.015 | -0.1183 | No | ||
82 | S100A5 | 4120592 | 8860 | -0.015 | -0.1193 | No | ||
83 | ANXA7 | 6110446 | 9021 | -0.018 | -0.1279 | No | ||
84 | C3AR1 | 5720131 | 9056 | -0.019 | -0.1296 | No | ||
85 | SFTPC | 3290133 | 9209 | -0.021 | -0.1377 | No | ||
86 | MYBPH | 2190711 | 9266 | -0.022 | -0.1405 | No | ||
87 | PSMD11 | 2340538 6510053 | 9447 | -0.025 | -0.1501 | No | ||
88 | IGSF9 | 1770411 | 9449 | -0.025 | -0.1500 | No | ||
89 | P2RXL1 | 4730390 5220446 | 9477 | -0.026 | -0.1513 | No | ||
90 | PRDM1 | 3170347 3520301 | 9666 | -0.030 | -0.1613 | No | ||
91 | GJB3 | 2650040 | 9686 | -0.030 | -0.1621 | No | ||
92 | GAB2 | 1410280 2340520 4280040 | 9815 | -0.033 | -0.1688 | No | ||
93 | WDFY3 | 3610041 4560333 4570273 | 9869 | -0.034 | -0.1714 | No | ||
94 | LPP | 1660541 | 9890 | -0.034 | -0.1722 | No | ||
95 | GFAP | 2060092 | 9930 | -0.035 | -0.1741 | No | ||
96 | TIAL1 | 4150048 6510605 | 9953 | -0.036 | -0.1750 | No | ||
97 | SPATS2 | 2360066 | 10071 | -0.039 | -0.1811 | No | ||
98 | NR0B2 | 2470692 | 10261 | -0.042 | -0.1910 | No | ||
99 | KBTBD5 | 6350025 | 10299 | -0.043 | -0.1927 | No | ||
100 | ELK3 | 460377 1400762 3710497 | 10471 | -0.047 | -0.2017 | No | ||
101 | EIF3S1 | 6130368 6770044 | 10825 | -0.055 | -0.2204 | No | ||
102 | TRIB1 | 2320435 | 10969 | -0.058 | -0.2278 | No | ||
103 | SCEL | 3190129 | 10975 | -0.058 | -0.2276 | No | ||
104 | DHRS3 | 360609 | 11160 | -0.063 | -0.2371 | No | ||
105 | FGF12 | 1740446 2360037 | 11185 | -0.064 | -0.2380 | No | ||
106 | OLR1 | 50025 3840484 | 11475 | -0.073 | -0.2531 | No | ||
107 | AK5 | 6290348 | 11599 | -0.077 | -0.2592 | No | ||
108 | GPR3 | 2970452 | 11609 | -0.077 | -0.2592 | No | ||
109 | TLL1 | 2680315 | 11696 | -0.081 | -0.2632 | No | ||
110 | IL23A | 6290044 | 11743 | -0.082 | -0.2651 | No | ||
111 | PTPRH | 3870070 | 11751 | -0.083 | -0.2649 | No | ||
112 | SFN | 6290301 7510608 | 11872 | -0.087 | -0.2708 | No | ||
113 | RIMS1 | 5670022 | 11892 | -0.088 | -0.2712 | No | ||
114 | MMP7 | 1780497 | 11916 | -0.089 | -0.2718 | No | ||
115 | MMP9 | 580338 | 12075 | -0.096 | -0.2797 | No | ||
116 | BMP2 | 6620687 | 12259 | -0.104 | -0.2888 | No | ||
117 | MAP1A | 4920576 | 12429 | -0.114 | -0.2972 | No | ||
118 | ST18 | 5720537 | 12571 | -0.121 | -0.3039 | No | ||
119 | ELA1 | 3390167 | 12593 | -0.122 | -0.3042 | No | ||
120 | STX17 | 2260037 | 12604 | -0.123 | -0.3038 | No | ||
121 | PVALB | 5570450 | 12646 | -0.126 | -0.3052 | No | ||
122 | PSME4 | 380348 1770131 | 12656 | -0.126 | -0.3047 | No | ||
123 | EEF1A2 | 2260162 5290086 | 12751 | -0.134 | -0.3088 | No | ||
124 | GGN | 1410528 4210082 5290170 | 12880 | -0.142 | -0.3148 | No | ||
125 | COBL | 2480452 6110066 | 12921 | -0.145 | -0.3159 | No | ||
126 | DIRAS1 | 2640270 | 12992 | -0.150 | -0.3186 | No | ||
127 | FLNC | 2360048 5050270 | 13267 | -0.171 | -0.3322 | No | ||
128 | AXIN2 | 3850131 | 13627 | -0.208 | -0.3502 | No | ||
129 | STAT5B | 6200026 | 13637 | -0.210 | -0.3491 | No | ||
130 | HSPB7 | 1190441 | 13729 | -0.220 | -0.3525 | No | ||
131 | NRIP3 | 1340372 | 13911 | -0.240 | -0.3605 | No | ||
132 | PLEC1 | 6520292 50500 380075 1570088 2510692 2630497 2680017 2900746 4560497 4850376 6290398 7040471 | 14274 | -0.293 | -0.3780 | No | ||
133 | RB1CC1 | 510494 7100072 | 14304 | -0.298 | -0.3775 | No | ||
134 | GADD45A | 2900717 | 14582 | -0.346 | -0.3900 | No | ||
135 | PAPPA | 4230463 | 14662 | -0.361 | -0.3916 | No | ||
136 | CLSTN3 | 2350685 | 14822 | -0.396 | -0.3974 | No | ||
137 | EPHA2 | 5890056 | 14854 | -0.403 | -0.3961 | No | ||
138 | VIM | 20431 | 15151 | -0.483 | -0.4087 | No | ||
139 | BLMH | 1410438 | 15152 | -0.483 | -0.4052 | No | ||
140 | RTN4 | 50725 630647 870097 870184 | 15236 | -0.512 | -0.4059 | No | ||
141 | DCN | 510332 5340026 5900711 6550092 | 15257 | -0.517 | -0.4033 | No | ||
142 | MDFI | 6200041 | 15343 | -0.546 | -0.4039 | No | ||
143 | ADORA2A | 1990687 | 15521 | -0.610 | -0.4091 | No | ||
144 | NFRKB | 3130538 | 15572 | -0.632 | -0.4072 | No | ||
145 | PSMD2 | 4670706 5050364 | 15757 | -0.711 | -0.4120 | No | ||
146 | TMEM24 | 5860039 | 15819 | -0.746 | -0.4099 | No | ||
147 | SCRN1 | 6040025 6580019 | 15889 | -0.786 | -0.4079 | No | ||
148 | BAZ2A | 730184 | 16198 | -0.958 | -0.4177 | Yes | ||
149 | FHL3 | 1090369 2650017 | 16213 | -0.968 | -0.4114 | Yes | ||
150 | PADI4 | 1740075 4810441 | 16280 | -1.002 | -0.4077 | Yes | ||
151 | NDRG2 | 450403 | 16341 | -1.032 | -0.4034 | Yes | ||
152 | AP2A2 | 130082 | 16438 | -1.086 | -0.4007 | Yes | ||
153 | HSPB8 | 540563 | 16555 | -1.166 | -0.3986 | Yes | ||
154 | PDGFRB | 6450279 | 16571 | -1.174 | -0.3908 | Yes | ||
155 | RIT1 | 5390338 | 16617 | -1.206 | -0.3845 | Yes | ||
156 | SYTL1 | 510487 | 16683 | -1.252 | -0.3789 | Yes | ||
157 | ECM1 | 940068 5390309 | 16804 | -1.342 | -0.3757 | Yes | ||
158 | VASP | 7050500 | 16831 | -1.374 | -0.3671 | Yes | ||
159 | ABHD4 | 6760450 | 16929 | -1.462 | -0.3618 | Yes | ||
160 | UBQLN1 | 110280 730376 2470133 6590594 | 16948 | -1.469 | -0.3521 | Yes | ||
161 | TGFBR2 | 1780711 1980537 6550398 | 17052 | -1.525 | -0.3466 | Yes | ||
162 | TAGLN2 | 4560121 | 17183 | -1.619 | -0.3418 | Yes | ||
163 | DCTN2 | 540471 3780717 | 17212 | -1.640 | -0.3314 | Yes | ||
164 | ABHD2 | 4850504 6840010 | 17346 | -1.761 | -0.3259 | Yes | ||
165 | UBE2C | 6130017 | 17457 | -1.873 | -0.3182 | Yes | ||
166 | NCDN | 50040 1980739 3520603 | 17519 | -1.916 | -0.3076 | Yes | ||
167 | ADCK4 | 1660180 | 17583 | -1.985 | -0.2966 | Yes | ||
168 | ROM1 | 3130685 | 17638 | -2.044 | -0.2847 | Yes | ||
169 | PKP3 | 3710048 | 17669 | -2.072 | -0.2712 | Yes | ||
170 | RAB3D | 4210253 | 17701 | -2.109 | -0.2576 | Yes | ||
171 | TBC1D17 | 1780450 | 17803 | -2.248 | -0.2467 | Yes | ||
172 | CAMKK1 | 6370324 | 17832 | -2.283 | -0.2316 | Yes | ||
173 | HDAC3 | 4060072 | 17839 | -2.296 | -0.2153 | Yes | ||
174 | ENO1 | 5340128 | 17995 | -2.530 | -0.2053 | Yes | ||
175 | LMNA | 520471 1500075 3190167 4210020 | 18022 | -2.565 | -0.1880 | Yes | ||
176 | ETV5 | 110017 | 18034 | -2.603 | -0.1697 | Yes | ||
177 | ITPKC | 5420021 | 18099 | -2.678 | -0.1537 | Yes | ||
178 | CAPNS1 | 3940113 | 18173 | -2.827 | -0.1371 | Yes | ||
179 | ABCA2 | 5050039 | 18231 | -2.965 | -0.1187 | Yes | ||
180 | VAMP5 | 3830300 | 18347 | -3.288 | -0.1010 | Yes | ||
181 | ABCD1 | 5670373 | 18368 | -3.366 | -0.0776 | Yes | ||
182 | MAPK3 | 580161 4780035 | 18380 | -3.390 | -0.0536 | Yes | ||
183 | AKT1S1 | 1660048 | 18416 | -3.525 | -0.0299 | Yes | ||
184 | ALDOA | 6290672 | 18596 | -5.593 | 0.0011 | Yes |