Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch_repos |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos |
Upregulated in class | truncNotch |
GeneSet | V$AP1_Q4 |
Enrichment Score (ES) | -0.43273684 |
Normalized Enrichment Score (NES) | -1.2620109 |
Nominal p-value | 0.03927987 |
FDR q-value | 0.94008005 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | SRPK2 | 6380341 | 87 | 4.282 | 0.0270 | No | ||
2 | TRIM8 | 6130441 | 453 | 2.806 | 0.0279 | No | ||
3 | EIF4G1 | 4070446 | 496 | 2.717 | 0.0457 | No | ||
4 | XPOT | 7050184 | 553 | 2.580 | 0.0618 | No | ||
5 | ICK | 1580746 3140021 | 568 | 2.543 | 0.0799 | No | ||
6 | CYFIP1 | 5690082 | 664 | 2.374 | 0.0923 | No | ||
7 | RPA3 | 5700136 | 822 | 2.144 | 0.0996 | No | ||
8 | NEFH | 630239 | 1061 | 1.821 | 0.1002 | No | ||
9 | KCNH2 | 1170451 | 1099 | 1.779 | 0.1113 | No | ||
10 | PDAP1 | 1410735 | 1100 | 1.779 | 0.1245 | No | ||
11 | TCF12 | 3610324 7000156 | 1276 | 1.578 | 0.1267 | No | ||
12 | RBBP7 | 430113 450450 2370309 | 1507 | 1.334 | 0.1241 | No | ||
13 | USP3 | 2060332 | 1681 | 1.162 | 0.1233 | No | ||
14 | BTK | 3130044 | 1814 | 1.068 | 0.1240 | No | ||
15 | SLC16A6 | 1690156 | 1865 | 1.035 | 0.1290 | No | ||
16 | LAMC1 | 4730025 | 2095 | 0.908 | 0.1232 | No | ||
17 | POLR3E | 380152 | 2169 | 0.869 | 0.1257 | No | ||
18 | IL10 | 2340685 2640541 2850403 6590286 | 2181 | 0.859 | 0.1315 | No | ||
19 | PKN3 | 2260538 | 2249 | 0.816 | 0.1339 | No | ||
20 | APOBEC1 | 4610022 | 2287 | 0.801 | 0.1378 | No | ||
21 | CMAS | 2190129 | 2480 | 0.688 | 0.1325 | No | ||
22 | MAP2K1 | 840739 | 2487 | 0.683 | 0.1372 | No | ||
23 | RIN1 | 510593 | 2853 | 0.520 | 0.1212 | No | ||
24 | PSMD4 | 430068 | 2925 | 0.488 | 0.1210 | No | ||
25 | ABI3 | 1740563 | 3038 | 0.448 | 0.1182 | No | ||
26 | SCOC | 610048 2230053 | 3099 | 0.427 | 0.1181 | No | ||
27 | MCART1 | 5270059 | 3180 | 0.397 | 0.1167 | No | ||
28 | LRRFIP2 | 670575 730152 6590438 | 3289 | 0.359 | 0.1135 | No | ||
29 | LTBP3 | 1190162 2650440 6520451 | 3298 | 0.354 | 0.1157 | No | ||
30 | PDE4D | 2470528 6660014 | 3326 | 0.349 | 0.1168 | No | ||
31 | VDR | 130156 510438 | 3329 | 0.348 | 0.1193 | No | ||
32 | TCF7 | 3800736 5390181 | 3339 | 0.346 | 0.1214 | No | ||
33 | ROCK2 | 1780035 5720025 | 3498 | 0.295 | 0.1150 | No | ||
34 | CASK | 2340215 3290576 6770215 | 3581 | 0.271 | 0.1125 | No | ||
35 | EIF4E | 1580403 70133 6380215 | 3604 | 0.264 | 0.1133 | No | ||
36 | APBA2BP | 5700341 | 3619 | 0.259 | 0.1145 | No | ||
37 | BACH1 | 290195 | 3662 | 0.249 | 0.1140 | No | ||
38 | RABEP1 | 4760427 6200463 | 3673 | 0.247 | 0.1153 | No | ||
39 | CDKN1A | 4050088 6400706 | 3730 | 0.231 | 0.1140 | No | ||
40 | PIM2 | 840136 5720692 7100577 | 3732 | 0.231 | 0.1156 | No | ||
41 | NEK6 | 3360687 | 3818 | 0.213 | 0.1126 | No | ||
42 | EVI2B | 1050465 | 3861 | 0.206 | 0.1118 | No | ||
43 | COL27A1 | 1740390 | 3864 | 0.205 | 0.1133 | No | ||
44 | PITPNC1 | 3990017 | 3868 | 0.205 | 0.1146 | No | ||
45 | LAPTM5 | 5550372 | 4030 | 0.172 | 0.1071 | No | ||
46 | IBRDC2 | 5130041 | 4167 | 0.152 | 0.1009 | No | ||
47 | CREM | 840156 6380438 6660041 6660168 | 4221 | 0.144 | 0.0991 | No | ||
48 | USP2 | 1190292 1240253 4850035 | 4272 | 0.138 | 0.0974 | No | ||
49 | NRAS | 6900577 | 4328 | 0.132 | 0.0954 | No | ||
50 | PCDH9 | 2100136 | 4371 | 0.126 | 0.0940 | No | ||
51 | LAMC2 | 450692 2680041 4200059 4670148 | 4629 | 0.102 | 0.0808 | No | ||
52 | AKT3 | 1580270 3290278 | 4634 | 0.102 | 0.0814 | No | ||
53 | CMYA1 | 6900632 | 4725 | 0.095 | 0.0772 | No | ||
54 | UBE3A | 1240152 2690438 5860609 | 4870 | 0.084 | 0.0700 | No | ||
55 | IL6 | 380133 | 4953 | 0.080 | 0.0661 | No | ||
56 | GNAI1 | 4560390 | 5227 | 0.065 | 0.0518 | No | ||
57 | RAD23B | 2190671 | 5234 | 0.065 | 0.0520 | No | ||
58 | AKAP1 | 110148 1740735 2260019 7000563 | 5552 | 0.053 | 0.0352 | No | ||
59 | XLKD1 | 520441 | 5562 | 0.053 | 0.0351 | No | ||
60 | PTPRN | 5900577 | 5725 | 0.048 | 0.0266 | No | ||
61 | GOLGA4 | 460300 | 5816 | 0.045 | 0.0221 | No | ||
62 | HOXD3 | 6450154 | 6348 | 0.030 | -0.0065 | No | ||
63 | FAP | 4560019 | 6354 | 0.030 | -0.0065 | No | ||
64 | LAMB3 | 7100301 | 6691 | 0.023 | -0.0246 | No | ||
65 | UCN2 | 4590372 | 6699 | 0.023 | -0.0248 | No | ||
66 | USP13 | 1450670 | 6819 | 0.020 | -0.0311 | No | ||
67 | SH3RF2 | 6200600 | 7207 | 0.013 | -0.0520 | No | ||
68 | ZIC4 | 1500082 | 7250 | 0.012 | -0.0542 | No | ||
69 | IL9 | 3440338 | 7451 | 0.008 | -0.0650 | No | ||
70 | PAX9 | 3850519 | 7456 | 0.008 | -0.0652 | No | ||
71 | DSTN | 3140592 | 7472 | 0.008 | -0.0659 | No | ||
72 | EFNA1 | 3840672 | 7533 | 0.007 | -0.0691 | No | ||
73 | TRPV3 | 540341 | 7659 | 0.005 | -0.0759 | No | ||
74 | MAPRE3 | 7050504 | 7967 | -0.000 | -0.0925 | No | ||
75 | IL1RN | 2370333 | 8021 | -0.001 | -0.0954 | No | ||
76 | AP2B1 | 1450184 2370148 3520139 4850593 | 8111 | -0.003 | -0.1002 | No | ||
77 | SHC3 | 2690398 | 8135 | -0.003 | -0.1014 | No | ||
78 | CRYBA2 | 5900138 | 8164 | -0.003 | -0.1029 | No | ||
79 | BNIP3 | 3140270 | 8199 | -0.004 | -0.1047 | No | ||
80 | PLAC1 | 2350594 | 8325 | -0.006 | -0.1115 | No | ||
81 | HOXA11 | 6980133 | 8363 | -0.007 | -0.1134 | No | ||
82 | UCHL3 | 1240735 | 8697 | -0.012 | -0.1314 | No | ||
83 | EDN1 | 1770047 | 8749 | -0.013 | -0.1341 | No | ||
84 | FBXW11 | 6450632 | 8838 | -0.015 | -0.1387 | No | ||
85 | S100A5 | 4120592 | 8860 | -0.015 | -0.1398 | No | ||
86 | ANXA7 | 6110446 | 9021 | -0.018 | -0.1483 | No | ||
87 | PSMA3 | 5900047 7040161 | 9078 | -0.019 | -0.1512 | No | ||
88 | MYBPH | 2190711 | 9266 | -0.022 | -0.1612 | No | ||
89 | PSMD11 | 2340538 6510053 | 9447 | -0.025 | -0.1708 | No | ||
90 | PRDM1 | 3170347 3520301 | 9666 | -0.030 | -0.1824 | No | ||
91 | GJB3 | 2650040 | 9686 | -0.030 | -0.1832 | No | ||
92 | GAB2 | 1410280 2340520 4280040 | 9815 | -0.033 | -0.1899 | No | ||
93 | EYA1 | 1450278 5220390 | 9835 | -0.033 | -0.1907 | No | ||
94 | WDFY3 | 3610041 4560333 4570273 | 9869 | -0.034 | -0.1922 | No | ||
95 | LPP | 1660541 | 9890 | -0.034 | -0.1930 | No | ||
96 | TIAL1 | 4150048 6510605 | 9953 | -0.036 | -0.1961 | No | ||
97 | KBTBD5 | 6350025 | 10299 | -0.043 | -0.2145 | No | ||
98 | ELK3 | 460377 1400762 3710497 | 10471 | -0.047 | -0.2235 | No | ||
99 | FGF11 | 840292 | 10619 | -0.050 | -0.2311 | No | ||
100 | EIF3S1 | 6130368 6770044 | 10825 | -0.055 | -0.2418 | No | ||
101 | TRIB1 | 2320435 | 10969 | -0.058 | -0.2491 | No | ||
102 | FGF12 | 1740446 2360037 | 11185 | -0.064 | -0.2603 | No | ||
103 | ZIC1 | 670113 | 11283 | -0.067 | -0.2651 | No | ||
104 | DNM1 | 1660097 5340519 | 11529 | -0.075 | -0.2778 | No | ||
105 | AK5 | 6290348 | 11599 | -0.077 | -0.2810 | No | ||
106 | GPR3 | 2970452 | 11609 | -0.077 | -0.2809 | No | ||
107 | LIFR | 3360068 3830102 | 11707 | -0.081 | -0.2856 | No | ||
108 | IL23A | 6290044 | 11743 | -0.082 | -0.2869 | No | ||
109 | PTPRH | 3870070 | 11751 | -0.083 | -0.2866 | No | ||
110 | SFN | 6290301 7510608 | 11872 | -0.087 | -0.2925 | No | ||
111 | MMP7 | 1780497 | 11916 | -0.089 | -0.2942 | No | ||
112 | ESRRB | 3870082 | 12002 | -0.092 | -0.2981 | No | ||
113 | LRP1B | 1450193 | 12044 | -0.094 | -0.2996 | No | ||
114 | MMP9 | 580338 | 12075 | -0.096 | -0.3005 | No | ||
115 | LRRC15 | 3940609 | 12076 | -0.096 | -0.2998 | No | ||
116 | BMP2 | 6620687 | 12259 | -0.104 | -0.3089 | No | ||
117 | MAP1A | 4920576 | 12429 | -0.114 | -0.3173 | No | ||
118 | ST18 | 5720537 | 12571 | -0.121 | -0.3240 | No | ||
119 | ELA1 | 3390167 | 12593 | -0.122 | -0.3243 | No | ||
120 | STX17 | 2260037 | 12604 | -0.123 | -0.3239 | No | ||
121 | GPR150 | 2570440 | 12727 | -0.131 | -0.3295 | No | ||
122 | EEF1A2 | 2260162 5290086 | 12751 | -0.134 | -0.3298 | No | ||
123 | GGN | 1410528 4210082 5290170 | 12880 | -0.142 | -0.3357 | No | ||
124 | CCL22 | 6380086 | 13025 | -0.153 | -0.3424 | No | ||
125 | HS3ST3B1 | 380040 | 13244 | -0.169 | -0.3530 | No | ||
126 | GSN | 3830168 | 13349 | -0.177 | -0.3573 | No | ||
127 | PADI3 | 6520072 | 13367 | -0.179 | -0.3569 | No | ||
128 | CORO1C | 4570397 | 13442 | -0.186 | -0.3595 | No | ||
129 | AXIN2 | 3850131 | 13627 | -0.208 | -0.3680 | No | ||
130 | STAT5B | 6200026 | 13637 | -0.210 | -0.3669 | No | ||
131 | HSPB7 | 1190441 | 13729 | -0.220 | -0.3702 | No | ||
132 | NRIP3 | 1340372 | 13911 | -0.240 | -0.3783 | No | ||
133 | APOB48R | 2810070 | 13987 | -0.250 | -0.3805 | No | ||
134 | IRAK1 | 4120593 | 14010 | -0.252 | -0.3798 | No | ||
135 | RB1CC1 | 510494 7100072 | 14304 | -0.298 | -0.3935 | No | ||
136 | PAPPA | 4230463 | 14662 | -0.361 | -0.4102 | No | ||
137 | PTPRR | 130121 3990273 | 14677 | -0.365 | -0.4083 | No | ||
138 | ARRDC4 | 2810019 | 14775 | -0.387 | -0.4107 | No | ||
139 | CLSTN3 | 2350685 | 14822 | -0.396 | -0.4102 | No | ||
140 | EPHA2 | 5890056 | 14854 | -0.403 | -0.4089 | No | ||
141 | VIM | 20431 | 15151 | -0.483 | -0.4214 | No | ||
142 | BLMH | 1410438 | 15152 | -0.483 | -0.4178 | No | ||
143 | DUSP13 | 6400152 | 15219 | -0.508 | -0.4177 | No | ||
144 | RTN4 | 50725 630647 870097 870184 | 15236 | -0.512 | -0.4147 | No | ||
145 | MDFI | 6200041 | 15343 | -0.546 | -0.4165 | No | ||
146 | ADORA2A | 1990687 | 15521 | -0.610 | -0.4215 | No | ||
147 | NFRKB | 3130538 | 15572 | -0.632 | -0.4196 | No | ||
148 | MMP19 | 5080377 | 15774 | -0.722 | -0.4251 | No | ||
149 | SCRN1 | 6040025 6580019 | 15889 | -0.786 | -0.4255 | No | ||
150 | EEF1A1 | 1980193 1990195 4670735 | 15982 | -0.835 | -0.4243 | No | ||
151 | IGFBP6 | 1580181 | 16138 | -0.921 | -0.4259 | Yes | ||
152 | DTX2 | 4210041 7000008 | 16190 | -0.950 | -0.4217 | Yes | ||
153 | BAZ2A | 730184 | 16198 | -0.958 | -0.4149 | Yes | ||
154 | FHL3 | 1090369 2650017 | 16213 | -0.968 | -0.4085 | Yes | ||
155 | FKBP8 | 4060019 | 16248 | -0.987 | -0.4031 | Yes | ||
156 | AP2A2 | 130082 | 16438 | -1.086 | -0.4053 | Yes | ||
157 | STOML2 | 1940487 | 16439 | -1.086 | -0.3973 | Yes | ||
158 | ISG20 | 1770750 | 16469 | -1.105 | -0.3907 | Yes | ||
159 | PDGFRB | 6450279 | 16571 | -1.174 | -0.3875 | Yes | ||
160 | SYTL1 | 510487 | 16683 | -1.252 | -0.3842 | Yes | ||
161 | CIZ1 | 4150128 6130484 | 16869 | -1.413 | -0.3838 | Yes | ||
162 | ABHD4 | 6760450 | 16929 | -1.462 | -0.3762 | Yes | ||
163 | UBQLN1 | 110280 730376 2470133 6590594 | 16948 | -1.469 | -0.3663 | Yes | ||
164 | TGFBR2 | 1780711 1980537 6550398 | 17052 | -1.525 | -0.3606 | Yes | ||
165 | BAG2 | 2900324 | 17077 | -1.540 | -0.3505 | Yes | ||
166 | TAGLN2 | 4560121 | 17183 | -1.619 | -0.3442 | Yes | ||
167 | DCTN2 | 540471 3780717 | 17212 | -1.640 | -0.3336 | Yes | ||
168 | TNFRSF12A | 4810253 | 17287 | -1.716 | -0.3249 | Yes | ||
169 | ABHD2 | 4850504 6840010 | 17346 | -1.761 | -0.3150 | Yes | ||
170 | UBE2C | 6130017 | 17457 | -1.873 | -0.3072 | Yes | ||
171 | ROM1 | 3130685 | 17638 | -2.044 | -0.3018 | Yes | ||
172 | TBC1D17 | 1780450 | 17803 | -2.248 | -0.2941 | Yes | ||
173 | CAMKK1 | 6370324 | 17832 | -2.283 | -0.2787 | Yes | ||
174 | HDAC3 | 4060072 | 17839 | -2.296 | -0.2620 | Yes | ||
175 | KCNN4 | 2680129 | 18009 | -2.550 | -0.2523 | Yes | ||
176 | PPP1R9B | 3130619 | 18017 | -2.558 | -0.2338 | Yes | ||
177 | LMNA | 520471 1500075 3190167 4210020 | 18022 | -2.565 | -0.2150 | Yes | ||
178 | ETV5 | 110017 | 18034 | -2.603 | -0.1964 | Yes | ||
179 | CAPNS1 | 3940113 | 18173 | -2.827 | -0.1829 | Yes | ||
180 | CD151 | 1450592 3780309 | 18269 | -3.071 | -0.1654 | Yes | ||
181 | MAPK3 | 580161 4780035 | 18380 | -3.390 | -0.1462 | Yes | ||
182 | AKT1S1 | 1660048 | 18416 | -3.525 | -0.1221 | Yes | ||
183 | LIMK1 | 5080064 | 18452 | -3.660 | -0.0969 | Yes | ||
184 | ABCB6 | 6350138 | 18481 | -3.862 | -0.0698 | Yes | ||
185 | GNGT2 | 540176 | 18566 | -4.702 | -0.0396 | Yes | ||
186 | RPL27A | 3130451 110195 6840494 | 18599 | -5.709 | 0.0009 | Yes |