DatasetSet_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls
#absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls
#absentNotch_versus_truncNotch_repos
Phenotypephenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos
Upregulated in classabsentNotch
GeneSetUVC_XPCS_4HR_DN
Enrichment Score (ES)0.5699517
Normalized Enrichment Score (NES)1.7252246
Nominal p-value0.0
FDR q-value0.0402526
FWER p-Value0.461
Table: GSEA Results Summary



Fig 1: Enrichment plot: UVC_XPCS_4HR_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1PTK2178014816.9370.0601Yes
2APPBP25130215135.7760.1096Yes
3SRPK26380341874.2820.1427Yes
4TLK171006051833.6960.1696Yes
5KLF7503901893.6600.2011Yes
6MTAP21201362773.3210.2251Yes
7FCHSD257200922933.2560.2526Yes
8PARG501394582.7970.2679Yes
9CUTL11570113 1770091 1850273 2100286 53406054692.7710.2914Yes
10CREBBP5690035 70400505352.6250.3106Yes
11NCOA136104386372.4180.3261Yes
12RBM394230458 64502806752.3550.3445Yes
13ZNF292840736 15003907342.2630.3610Yes
14ORC5L1940133 19407117542.2340.3793Yes
15UGCG34200537552.2340.3987Yes
16RASA112403157942.1760.4155Yes
17EIF2C27704518802.0770.4289Yes
18TLK211701619082.0290.4450Yes
19UPF248104719851.9060.4575Yes
20RUNX1384071110431.8370.4703Yes
21TLE1540390 1580309 371001911081.7700.4822Yes
22APRIN281005011621.7120.4941Yes
23CHD1459004811761.6920.5081Yes
24CENTG2421005312361.6260.5190Yes
25TIAM1542028814201.4240.5214Yes
26MARK3237045017111.1450.5156Yes
27ITSN278048417201.1390.5251Yes
28MECP2194045018031.0750.5300Yes
29REV3L109071718231.0650.5382Yes
30SEC24B460717 306004018851.0210.5437Yes
31BHLHB2704060321520.8780.5369Yes
32NCOA3454019522840.8020.5367Yes
33DYRK1A319018123530.7630.5397Yes
34RNGTT780152 780746 109047123900.7490.5442Yes
35PPP1R12A4070066 459016223930.7480.5506Yes
36CNOT42320242 676070624400.7130.5543Yes
37TRIM33580619 2230280 3990433 620074725320.6590.5551Yes
38SOS2206072225890.6390.5576Yes
39SMURF2194016126240.6220.5611Yes
40ANKRD172120402 3850035 640004427410.5650.5597Yes
41THRAP2492060028430.5240.5588Yes
42IFRD1459021528560.5190.5626Yes
43ZNF148642040330120.4590.5582Yes
44STRN31450093 620068530210.4540.5617Yes
45ARFGEF1676049430310.4520.5651Yes
46CTBP2430309 371007930470.4450.5682Yes
47MARCH73800020 662016832240.3830.5620Yes
48ATF22260348 248044132260.3830.5652Yes
49NRIP1319003932690.3690.5662Yes
50MYC380541 467017033720.3370.5636Yes
51BMPR1A2190193 406060333760.3350.5663Yes
52CREB11500717 2230358 3610600 655060134140.3230.5671Yes
53MALT1467029234500.3110.5679Yes
54STK3710042734620.3060.5700Yes
55BARD1317034836120.2610.5641No
56FNDC3A2690097 329004436350.2550.5652No
57ZFYVE96980288 710001736370.2540.5673No
58TCF7L22190348 522011336670.2480.5679No
59MYO103830576 557009241540.1530.5429No
60PIP5K3536011243070.1340.5358No
61THRAP1247012143320.1310.5356No
62STARD1354072243640.1280.5351No
63ACVR1684067144750.1150.5301No
64PTPRK1450433 264014245790.1060.5254No
65TOPBP1602033345950.1050.5255No
66STAM3850008 476044146040.1040.5260No
67DAPK1557001047440.0930.5193No
68KLF6110541 536002647630.0920.5191No
69FYN2100468 4760520 485068747850.0910.5187No
70PTPN122030309 6020725 6130746 629060948510.0850.5160No
71RCOR1536071749100.0820.5135No
72IL638013349530.0800.5119No
73BLM520619 557017050350.0750.5082No
74ACSL3314019551010.0720.5053No
75IRAK1BP161003752110.0660.5000No
76GNAI1456039052270.0650.4997No
77MYST41400563 2570687 3360458 684040253360.0610.4944No
78F3294018054760.0560.4873No
79BICD1110128 294032455680.0530.4829No
80AKAP9510184 2060195 2470136 428004857090.0480.4757No
81IGF1R336049457190.0480.4756No
82ZCCHC113390731 536003957260.0480.4757No
83TGFBR3529057759230.0420.4654No
84TSPAN5677001959500.0410.4644No
85FGF5527020459540.0410.4646No
86ARHGAP12105018160600.0380.4592No
87TGFB2492029261930.0340.4524No
88SCHIP1456015265550.0260.4330No
89TIPARP5039765610.0260.4330No
90EHBP143034866300.0240.4295No
91VEGFC591049469220.0180.4139No
92CLASP2251013969490.0180.4126No
93GLRB2510433 428073669990.0170.4101No
94E2F5586057571630.0140.4014No
95USP15610592 352050472360.0120.3976No
96TLE41450064 150051973230.0100.3930No
97ARHGEF7169044173970.0090.3891No
98PVRL31400324 4200593 665012876100.0050.3777No
99PLEKHC1265006676200.0050.3773No
100PUM24200441 591044676930.0040.3734No
101PCTK2570067377910.0020.3681No
102KLF10485005679350.0000.3604No
103SHB49204947988-0.0010.3576No
104NUP15370004528186-0.0040.3469No
105SAMD4A11707178358-0.0070.3377No
106SATB224701818760-0.0140.3161No
107FBXW1164506328838-0.0150.3121No
108CTGF45405779137-0.0200.2961No
109RGS733900449297-0.0230.2877No
110SRGAP21050092 1230403 3830066 61302159714-0.0310.2654No
111TAF414501709716-0.0310.2656No
112WDR372630519 68403479760-0.0320.2636No
113TRIM2430546 117028610102-0.0390.2454No
114RNF13237002110237-0.0420.2385No
115CENPE285002210578-0.0490.2205No
116FBXL7662071110661-0.0510.2165No
117TERF1234011310806-0.0550.2092No
118CENPC161027311074-0.0610.1952No
119CNOT2520546 2060397 4610543 555011311210-0.0640.1885No
120GNAQ430670 4210131 590073611427-0.0720.1774No
121PHLPP344056311629-0.0780.1672No
122CENTD1257059211719-0.0810.1630No
123DDX1052074611849-0.0860.1568No
124MID14070114 476045811900-0.0890.1549No
125NFIB46045011926-0.0890.1543No
126SOS1705033812089-0.0960.1463No
127NCK16200575 651005012187-0.1000.1419No
128BCAR3166071712228-0.1020.1407No
129EPHA446075012418-0.1130.1314No
130KIF2A3990286 613057512527-0.1190.1266No
131DNMBP2810368 690040312757-0.1340.1153No
132CYR611240408 5290026 4120452 655000812825-0.1380.1129No
133TUBGCP3492056312924-0.1450.1088No
134IL1RAP50546 450711 1580397 3940301 5890181 637037313116-0.1590.0999No
135CD2AP194036913118-0.1590.1012No
136ZZZ3780133 2320239 2640452 5080706 655034113217-0.1670.0973No
137WNT5A840685 312015213276-0.1710.0957No
138PAFAH1B14230333 6420121 645006613670-0.2130.0762No
139CENPA508015413738-0.2210.0745No
140DOCK4591010213805-0.2290.0729No
141PBX31300424 3710577 618057513878-0.2360.0710No
142SPEN206004113919-0.2410.0710No
143RRAS2629017014142-0.2720.0613No
144EXT1454060314352-0.3070.0526No
145HOXB2645059214396-0.3140.0530No
146FGF2345043314449-0.3230.0530No
147MICAL3604033314510-0.3330.0526No
148SOCS53830398 710009314544-0.3390.0538No
149EGFR4920138 648052114611-0.3510.0533No
150CBLB3520465 467034814787-0.3900.0471No
151CDYL4200142 4730397 606040014892-0.4110.0451No
152ANKS1A5014814906-0.4150.0480No
153MTF25033315006-0.4380.0464No
154SWAP702810577 2850739 513059415100-0.4660.0454No
155DLC11090632 645059415250-0.5160.0418No
156CDK81050113 1190601 1780358 611010215335-0.5440.0420No
157ZHX2290045215396-0.5670.0436No
158ZHX346061515422-0.5760.0472No
159HIRA4480609 527016715491-0.6010.0488No
160AKAP102630504 591057715499-0.6030.0536No
161BTRC317013116231-0.9780.0225No
162RBM166290286 640018116548-1.1620.0154No
163ATXN23940017 481024216954-1.4730.0062No
164MTMR31050014 492018016991-1.4930.0172No
165MYST3527050017220-1.6480.0192No
166LHFPL245002017492-1.8940.0209No
167SLC25A12740073117566-1.9640.0340No
168PRR3344011218069-2.6420.0296No
Table: GSEA details [plain text format]



Fig 2: UVC_XPCS_4HR_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: UVC_XPCS_4HR_DN: Random ES distribution   
Gene set null distribution of ES for UVC_XPCS_4HR_DN