Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch_repos |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos |
Upregulated in class | absentNotch |
GeneSet | UVC_TTD_4HR_DN |
Enrichment Score (ES) | 0.61383563 |
Normalized Enrichment Score (NES) | 1.8949786 |
Nominal p-value | 0.0 |
FDR q-value | 0.0052051465 |
FWER p-Value | 0.0080 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PTK2 | 1780148 | 1 | 6.937 | 0.0389 | Yes | ||
2 | MAPK6 | 6760520 | 38 | 4.847 | 0.0641 | Yes | ||
3 | DHX15 | 870632 | 44 | 4.807 | 0.0908 | Yes | ||
4 | SPOP | 450035 | 60 | 4.589 | 0.1157 | Yes | ||
5 | FUBP1 | 5390373 | 71 | 4.465 | 0.1403 | Yes | ||
6 | SRPK2 | 6380341 | 87 | 4.282 | 0.1635 | Yes | ||
7 | ABI1 | 2850152 | 162 | 3.784 | 0.1807 | Yes | ||
8 | MAP2K4 | 5130133 | 175 | 3.735 | 0.2010 | Yes | ||
9 | TLK1 | 7100605 | 183 | 3.696 | 0.2213 | Yes | ||
10 | EIF4G3 | 670707 | 185 | 3.687 | 0.2420 | Yes | ||
11 | KLF7 | 50390 | 189 | 3.660 | 0.2623 | Yes | ||
12 | MNAT1 | 730292 2350364 | 243 | 3.445 | 0.2788 | Yes | ||
13 | FCHSD2 | 5720092 | 293 | 3.256 | 0.2944 | Yes | ||
14 | SLC4A7 | 2370056 | 447 | 2.822 | 0.3019 | Yes | ||
15 | PARG | 50139 | 458 | 2.797 | 0.3171 | Yes | ||
16 | CUTL1 | 1570113 1770091 1850273 2100286 5340605 | 469 | 2.771 | 0.3321 | Yes | ||
17 | GSK3B | 5360348 | 510 | 2.696 | 0.3450 | Yes | ||
18 | CREBBP | 5690035 7040050 | 535 | 2.625 | 0.3585 | Yes | ||
19 | HNRPDL | 1050102 1090181 5360471 | 603 | 2.480 | 0.3687 | Yes | ||
20 | UBL3 | 6450458 | 624 | 2.441 | 0.3813 | Yes | ||
21 | NCOA1 | 3610438 | 637 | 2.418 | 0.3942 | Yes | ||
22 | KIF23 | 5570112 | 668 | 2.363 | 0.4059 | Yes | ||
23 | RBM39 | 4230458 6450280 | 675 | 2.355 | 0.4188 | Yes | ||
24 | SIPA1L1 | 50292 | 709 | 2.305 | 0.4299 | Yes | ||
25 | TBL1X | 6400524 | 726 | 2.280 | 0.4418 | Yes | ||
26 | ZNF292 | 840736 1500390 | 734 | 2.263 | 0.4541 | Yes | ||
27 | ORC5L | 1940133 1940711 | 754 | 2.234 | 0.4656 | Yes | ||
28 | UGCG | 3420053 | 755 | 2.234 | 0.4782 | Yes | ||
29 | PPP2R5E | 70671 2120056 | 776 | 2.202 | 0.4894 | Yes | ||
30 | TLK2 | 1170161 | 908 | 2.029 | 0.4937 | Yes | ||
31 | UPF2 | 4810471 | 985 | 1.906 | 0.5003 | Yes | ||
32 | RUNX1 | 3840711 | 1043 | 1.837 | 0.5075 | Yes | ||
33 | TLE1 | 540390 1580309 3710019 | 1108 | 1.770 | 0.5139 | Yes | ||
34 | MPP6 | 6020148 | 1145 | 1.734 | 0.5217 | Yes | ||
35 | ARIH1 | 6900025 | 1168 | 1.698 | 0.5300 | Yes | ||
36 | CHD1 | 4590048 | 1176 | 1.692 | 0.5392 | Yes | ||
37 | CENTG2 | 4210053 | 1236 | 1.626 | 0.5451 | Yes | ||
38 | TCF12 | 3610324 7000156 | 1276 | 1.578 | 0.5518 | Yes | ||
39 | WDHD1 | 3450390 | 1289 | 1.563 | 0.5599 | Yes | ||
40 | ZNF638 | 6510112 | 1474 | 1.369 | 0.5576 | Yes | ||
41 | OGT | 2360131 4610333 | 1542 | 1.298 | 0.5613 | Yes | ||
42 | ITSN2 | 780484 | 1720 | 1.139 | 0.5580 | Yes | ||
43 | PRIM2A | 7000692 | 1791 | 1.081 | 0.5603 | Yes | ||
44 | EVI5 | 6380040 | 1809 | 1.070 | 0.5654 | Yes | ||
45 | REV3L | 1090717 | 1823 | 1.065 | 0.5706 | Yes | ||
46 | SEC24B | 460717 3060040 | 1885 | 1.021 | 0.5730 | Yes | ||
47 | ATBF1 | 1240131 7040465 | 1899 | 1.013 | 0.5780 | Yes | ||
48 | SOCS6 | 1170347 7100280 | 2052 | 0.938 | 0.5750 | Yes | ||
49 | CASP8 | 4850154 | 2097 | 0.907 | 0.5777 | Yes | ||
50 | BHLHB2 | 7040603 | 2152 | 0.878 | 0.5797 | Yes | ||
51 | CLASP1 | 6860279 | 2182 | 0.859 | 0.5830 | Yes | ||
52 | NCOA3 | 4540195 | 2284 | 0.802 | 0.5820 | Yes | ||
53 | WDR7 | 670279 1090121 | 2349 | 0.765 | 0.5828 | Yes | ||
54 | DYRK1A | 3190181 | 2353 | 0.763 | 0.5869 | Yes | ||
55 | LRIG1 | 1050136 | 2385 | 0.750 | 0.5894 | Yes | ||
56 | RNGTT | 780152 780746 1090471 | 2390 | 0.749 | 0.5934 | Yes | ||
57 | PPP1R12A | 4070066 4590162 | 2393 | 0.748 | 0.5975 | Yes | ||
58 | CNOT4 | 2320242 6760706 | 2440 | 0.713 | 0.5990 | Yes | ||
59 | SLC25A24 | 5360017 5860484 | 2499 | 0.676 | 0.5996 | Yes | ||
60 | LRP6 | 5130064 | 2504 | 0.674 | 0.6032 | Yes | ||
61 | TRIM33 | 580619 2230280 3990433 6200747 | 2532 | 0.659 | 0.6054 | Yes | ||
62 | SMURF2 | 1940161 | 2624 | 0.622 | 0.6040 | Yes | ||
63 | MSH3 | 6770575 | 2648 | 0.612 | 0.6062 | Yes | ||
64 | MAP4K5 | 3190286 4760300 5270070 5550494 | 2686 | 0.591 | 0.6075 | Yes | ||
65 | ANKRD17 | 2120402 3850035 6400044 | 2741 | 0.565 | 0.6077 | Yes | ||
66 | MPHOSPH1 | 4610427 | 2817 | 0.532 | 0.6066 | Yes | ||
67 | THRAP2 | 4920600 | 2843 | 0.524 | 0.6082 | Yes | ||
68 | IFRD1 | 4590215 | 2856 | 0.519 | 0.6105 | Yes | ||
69 | AQR | 3800139 | 2920 | 0.492 | 0.6098 | Yes | ||
70 | ZNF148 | 6420403 | 3012 | 0.459 | 0.6074 | Yes | ||
71 | STRN3 | 1450093 6200685 | 3021 | 0.454 | 0.6095 | Yes | ||
72 | ARFGEF1 | 6760494 | 3031 | 0.452 | 0.6116 | Yes | ||
73 | CTBP2 | 430309 3710079 | 3047 | 0.445 | 0.6133 | Yes | ||
74 | MELK | 130022 5220537 | 3082 | 0.430 | 0.6138 | Yes | ||
75 | MARCH7 | 3800020 6620168 | 3224 | 0.383 | 0.6083 | No | ||
76 | ATF2 | 2260348 2480441 | 3226 | 0.383 | 0.6104 | No | ||
77 | NRIP1 | 3190039 | 3269 | 0.369 | 0.6102 | No | ||
78 | E2F3 | 50162 460180 | 3320 | 0.350 | 0.6095 | No | ||
79 | STK3 | 7100427 | 3462 | 0.306 | 0.6035 | No | ||
80 | ZRF1 | 6020181 6510484 | 3489 | 0.297 | 0.6038 | No | ||
81 | ROCK2 | 1780035 5720025 | 3498 | 0.295 | 0.6050 | No | ||
82 | EIF4E | 1580403 70133 6380215 | 3604 | 0.264 | 0.6008 | No | ||
83 | BARD1 | 3170348 | 3612 | 0.261 | 0.6019 | No | ||
84 | FNDC3A | 2690097 3290044 | 3635 | 0.255 | 0.6021 | No | ||
85 | ZFYVE9 | 6980288 7100017 | 3637 | 0.254 | 0.6035 | No | ||
86 | TCF7L2 | 2190348 5220113 | 3667 | 0.248 | 0.6033 | No | ||
87 | ORC2L | 1990470 6510019 | 3731 | 0.231 | 0.6011 | No | ||
88 | STK39 | 50692 | 3853 | 0.207 | 0.5957 | No | ||
89 | MYO10 | 3830576 5570092 | 4154 | 0.153 | 0.5803 | No | ||
90 | PIP5K3 | 5360112 | 4307 | 0.134 | 0.5728 | No | ||
91 | THRAP1 | 2470121 | 4332 | 0.131 | 0.5722 | No | ||
92 | STARD13 | 540722 | 4364 | 0.128 | 0.5712 | No | ||
93 | UST | 2100053 | 4442 | 0.119 | 0.5677 | No | ||
94 | ACVR1 | 6840671 | 4475 | 0.115 | 0.5666 | No | ||
95 | PTPRK | 1450433 2640142 | 4579 | 0.106 | 0.5616 | No | ||
96 | TOPBP1 | 6020333 | 4595 | 0.105 | 0.5614 | No | ||
97 | JMJD2C | 3290341 | 4660 | 0.099 | 0.5585 | No | ||
98 | DAPK1 | 5570010 | 4744 | 0.093 | 0.5545 | No | ||
99 | FYN | 2100468 4760520 4850687 | 4785 | 0.091 | 0.5528 | No | ||
100 | PTPN12 | 2030309 6020725 6130746 6290609 | 4851 | 0.085 | 0.5498 | No | ||
101 | BLM | 520619 5570170 | 5035 | 0.075 | 0.5403 | No | ||
102 | IRAK1BP1 | 610037 | 5211 | 0.066 | 0.5311 | No | ||
103 | SEMA3C | 7000020 | 5225 | 0.066 | 0.5308 | No | ||
104 | GNAI1 | 4560390 | 5227 | 0.065 | 0.5311 | No | ||
105 | LARS2 | 7000706 | 5253 | 0.065 | 0.5301 | No | ||
106 | MYST4 | 1400563 2570687 3360458 6840402 | 5336 | 0.061 | 0.5260 | No | ||
107 | F3 | 2940180 | 5476 | 0.056 | 0.5187 | No | ||
108 | BICD1 | 110128 2940324 | 5568 | 0.053 | 0.5141 | No | ||
109 | ZCCHC11 | 3390731 5360039 | 5726 | 0.048 | 0.5058 | No | ||
110 | PARD3 | 3390324 5390541 | 5744 | 0.047 | 0.5052 | No | ||
111 | GOLGA4 | 460300 | 5816 | 0.045 | 0.5016 | No | ||
112 | TSPAN5 | 6770019 | 5950 | 0.041 | 0.4946 | No | ||
113 | FGF5 | 5270204 | 5954 | 0.041 | 0.4946 | No | ||
114 | EDG2 | 6290215 | 6059 | 0.038 | 0.4892 | No | ||
115 | ARHGAP12 | 1050181 | 6060 | 0.038 | 0.4894 | No | ||
116 | TGFB2 | 4920292 | 6193 | 0.034 | 0.4824 | No | ||
117 | SLC16A7 | 2320672 | 6469 | 0.028 | 0.4676 | No | ||
118 | MITF | 380056 | 6523 | 0.026 | 0.4649 | No | ||
119 | SCHIP1 | 4560152 | 6555 | 0.026 | 0.4634 | No | ||
120 | EHBP1 | 430348 | 6630 | 0.024 | 0.4595 | No | ||
121 | VEGFC | 5910494 | 6922 | 0.018 | 0.4438 | No | ||
122 | CLASP2 | 2510139 | 6949 | 0.018 | 0.4424 | No | ||
123 | AUH | 5570152 | 7200 | 0.013 | 0.4289 | No | ||
124 | TLE4 | 1450064 1500519 | 7323 | 0.010 | 0.4224 | No | ||
125 | ARHGEF7 | 1690441 | 7397 | 0.009 | 0.4184 | No | ||
126 | CRY1 | 6770039 | 7568 | 0.006 | 0.4092 | No | ||
127 | PLEKHC1 | 2650066 | 7620 | 0.005 | 0.4065 | No | ||
128 | PUM2 | 4200441 5910446 | 7693 | 0.004 | 0.4026 | No | ||
129 | PCTK2 | 5700673 | 7791 | 0.002 | 0.3974 | No | ||
130 | KLF10 | 4850056 | 7935 | 0.000 | 0.3896 | No | ||
131 | STAG1 | 1190300 1400722 4590100 | 7962 | -0.000 | 0.3882 | No | ||
132 | HOMER1 | 360131 1690092 1990300 4590068 | 7976 | -0.000 | 0.3875 | No | ||
133 | NEK7 | 4540026 | 8012 | -0.001 | 0.3856 | No | ||
134 | ARNT2 | 1740594 | 8081 | -0.002 | 0.3819 | No | ||
135 | NUP153 | 7000452 | 8186 | -0.004 | 0.3763 | No | ||
136 | SAMD4A | 1170717 | 8358 | -0.007 | 0.3670 | No | ||
137 | LYN | 6040600 | 8816 | -0.015 | 0.3423 | No | ||
138 | FBXW11 | 6450632 | 8838 | -0.015 | 0.3412 | No | ||
139 | CTGF | 4540577 | 9137 | -0.020 | 0.3251 | No | ||
140 | ITSN1 | 2640577 | 9240 | -0.022 | 0.3197 | No | ||
141 | RGS7 | 3390044 | 9297 | -0.023 | 0.3168 | No | ||
142 | SRGAP2 | 1050092 1230403 3830066 6130215 | 9714 | -0.031 | 0.2943 | No | ||
143 | TRIM24 | 7050670 | 9851 | -0.034 | 0.2871 | No | ||
144 | WDFY3 | 3610041 4560333 4570273 | 9869 | -0.034 | 0.2864 | No | ||
145 | PTPN2 | 130315 | 10057 | -0.038 | 0.2765 | No | ||
146 | ROR1 | 6220026 | 10155 | -0.040 | 0.2714 | No | ||
147 | RNF13 | 2370021 | 10237 | -0.042 | 0.2672 | No | ||
148 | ACVR2A | 6110647 | 10239 | -0.042 | 0.2674 | No | ||
149 | SYNJ2 | 3170524 | 10385 | -0.045 | 0.2598 | No | ||
150 | CENPE | 2850022 | 10578 | -0.049 | 0.2496 | No | ||
151 | FBXL7 | 6620711 | 10661 | -0.051 | 0.2455 | No | ||
152 | CNOT2 | 520546 2060397 4610543 5550113 | 11210 | -0.064 | 0.2161 | No | ||
153 | GNAQ | 430670 4210131 5900736 | 11427 | -0.072 | 0.2047 | No | ||
154 | ANAPC10 | 870086 1170037 2260129 | 11439 | -0.072 | 0.2045 | No | ||
155 | PHLPP | 3440563 | 11629 | -0.078 | 0.1947 | No | ||
156 | RGL1 | 1500097 6900450 | 11658 | -0.079 | 0.1936 | No | ||
157 | DDX10 | 520746 | 11849 | -0.086 | 0.1838 | No | ||
158 | MID1 | 4070114 4760458 | 11900 | -0.089 | 0.1816 | No | ||
159 | SOS1 | 7050338 | 12089 | -0.096 | 0.1719 | No | ||
160 | TRAM2 | 3940112 | 12119 | -0.098 | 0.1709 | No | ||
161 | BCAR3 | 1660717 | 12228 | -0.102 | 0.1656 | No | ||
162 | ATXN1 | 5550156 | 12348 | -0.109 | 0.1597 | No | ||
163 | EPHA4 | 460750 | 12418 | -0.113 | 0.1566 | No | ||
164 | KIF2A | 3990286 6130575 | 12527 | -0.119 | 0.1514 | No | ||
165 | DNMBP | 2810368 6900403 | 12757 | -0.134 | 0.1397 | No | ||
166 | TUBGCP3 | 4920563 | 12924 | -0.145 | 0.1315 | No | ||
167 | ARID5B | 110403 | 12985 | -0.150 | 0.1291 | No | ||
168 | GULP1 | 2230725 2350039 5570446 | 13076 | -0.156 | 0.1251 | No | ||
169 | IL1RAP | 50546 450711 1580397 3940301 5890181 6370373 | 13116 | -0.159 | 0.1238 | No | ||
170 | CD2AP | 1940369 | 13118 | -0.159 | 0.1247 | No | ||
171 | BMP2K | 60541 5570504 | 13165 | -0.163 | 0.1231 | No | ||
172 | ZZZ3 | 780133 2320239 2640452 5080706 6550341 | 13217 | -0.167 | 0.1213 | No | ||
173 | CREB5 | 2320368 | 13496 | -0.191 | 0.1072 | No | ||
174 | PAFAH1B1 | 4230333 6420121 6450066 | 13670 | -0.213 | 0.0990 | No | ||
175 | CENPA | 5080154 | 13738 | -0.221 | 0.0966 | No | ||
176 | SLIT1 | 50110 | 13847 | -0.233 | 0.0921 | No | ||
177 | PBX3 | 1300424 3710577 6180575 | 13878 | -0.236 | 0.0917 | No | ||
178 | MDN1 | 60671 770091 | 14022 | -0.254 | 0.0854 | No | ||
179 | RRAS2 | 6290170 | 14142 | -0.272 | 0.0805 | No | ||
180 | XRCC4 | 1690685 6660427 | 14349 | -0.306 | 0.0710 | No | ||
181 | EXT1 | 4540603 | 14352 | -0.307 | 0.0726 | No | ||
182 | FGF2 | 3450433 | 14449 | -0.323 | 0.0692 | No | ||
183 | PPAP2B | 3190397 4730280 | 14538 | -0.339 | 0.0663 | No | ||
184 | SOCS5 | 3830398 7100093 | 14544 | -0.339 | 0.0679 | No | ||
185 | EGFR | 4920138 6480521 | 14611 | -0.351 | 0.0663 | No | ||
186 | INPP5F | 60010 5360164 | 14737 | -0.377 | 0.0617 | No | ||
187 | IL7R | 2060088 6380500 | 14762 | -0.383 | 0.0625 | No | ||
188 | CBLB | 3520465 4670348 | 14787 | -0.390 | 0.0634 | No | ||
189 | CDYL | 4200142 4730397 6060400 | 14892 | -0.411 | 0.0600 | No | ||
190 | ANKS1A | 50148 | 14906 | -0.415 | 0.0617 | No | ||
191 | SSBP2 | 2260725 2900400 4730711 | 14986 | -0.435 | 0.0598 | No | ||
192 | MTF2 | 50333 | 15006 | -0.438 | 0.0612 | No | ||
193 | DAAM1 | 1500273 | 15017 | -0.442 | 0.0632 | No | ||
194 | SWAP70 | 2810577 2850739 5130594 | 15100 | -0.466 | 0.0613 | No | ||
195 | MGAT5 | 1770592 6940441 | 15238 | -0.513 | 0.0568 | No | ||
196 | RBM6 | 840279 3840563 4780129 6020446 | 15243 | -0.514 | 0.0594 | No | ||
197 | DLC1 | 1090632 6450594 | 15250 | -0.516 | 0.0620 | No | ||
198 | CDK8 | 1050113 1190601 1780358 6110102 | 15335 | -0.544 | 0.0605 | No | ||
199 | ZHX2 | 2900452 | 15396 | -0.567 | 0.0604 | No | ||
200 | ZHX3 | 460615 | 15422 | -0.576 | 0.0623 | No | ||
201 | PKN2 | 940746 2350168 | 15423 | -0.577 | 0.0655 | No | ||
202 | HIRA | 4480609 5270167 | 15491 | -0.601 | 0.0652 | No | ||
203 | HAS2 | 5360181 | 15725 | -0.694 | 0.0565 | No | ||
204 | PPP2R2A | 2900014 5700575 | 15890 | -0.786 | 0.0520 | No | ||
205 | PRKCA | 6400551 | 15989 | -0.839 | 0.0514 | No | ||
206 | CTAGE5 | 70053 2100435 6020692 | 16313 | -1.019 | 0.0395 | No | ||
207 | NUP98 | 2850465 | 16455 | -1.097 | 0.0380 | No | ||
208 | RBM16 | 6290286 6400181 | 16548 | -1.162 | 0.0395 | No | ||
209 | ATXN2 | 3940017 4810242 | 16954 | -1.473 | 0.0258 | No | ||
210 | MTMR3 | 1050014 4920180 | 16991 | -1.493 | 0.0322 | No | ||
211 | MYST3 | 5270500 | 17220 | -1.648 | 0.0291 | No | ||
212 | SMAD3 | 6450671 | 17349 | -1.764 | 0.0320 | No | ||
213 | LHFPL2 | 450020 | 17492 | -1.894 | 0.0349 | No | ||
214 | PEX14 | 520603 | 17592 | -1.999 | 0.0408 | No | ||
215 | IGF2BP3 | 2810161 4230338 | 18072 | -2.645 | 0.0296 | No |