Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch_repos |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos |
Upregulated in class | absentNotch |
GeneSet | UVC_HIGH_ALL_DN |
Enrichment Score (ES) | 0.5967763 |
Normalized Enrichment Score (NES) | 1.836138 |
Nominal p-value | 0.0 |
FDR q-value | 0.009750816 |
FWER p-Value | 0.045 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PTK2 | 1780148 | 1 | 6.937 | 0.0318 | Yes | ||
2 | LBR | 4540671 | 2 | 6.656 | 0.0623 | Yes | ||
3 | RAB14 | 6860139 | 21 | 5.314 | 0.0857 | Yes | ||
4 | MAPK6 | 6760520 | 38 | 4.847 | 0.1071 | Yes | ||
5 | NFYB | 1850053 | 49 | 4.754 | 0.1283 | Yes | ||
6 | SPOP | 450035 | 60 | 4.589 | 0.1488 | Yes | ||
7 | UBE2G1 | 2230546 5420528 7040463 | 80 | 4.350 | 0.1678 | Yes | ||
8 | THUMPD1 | 7510148 | 134 | 3.939 | 0.1829 | Yes | ||
9 | TLK1 | 7100605 | 183 | 3.696 | 0.1973 | Yes | ||
10 | PITPNB | 5130039 | 203 | 3.593 | 0.2127 | Yes | ||
11 | RARS | 380390 | 210 | 3.585 | 0.2289 | Yes | ||
12 | EMP1 | 4120438 | 220 | 3.541 | 0.2446 | Yes | ||
13 | RAB1A | 2370671 | 252 | 3.405 | 0.2585 | Yes | ||
14 | GTF2E1 | 4070014 | 258 | 3.384 | 0.2738 | Yes | ||
15 | NASP | 2260139 2940369 5130707 | 312 | 3.185 | 0.2855 | Yes | ||
16 | MPHOSPH6 | 5570164 | 370 | 3.011 | 0.2962 | Yes | ||
17 | KPNA2 | 3450114 | 394 | 2.961 | 0.3086 | Yes | ||
18 | CRKL | 4050427 | 415 | 2.887 | 0.3207 | Yes | ||
19 | MARCKS | 7040450 | 452 | 2.808 | 0.3316 | Yes | ||
20 | DDX3X | 2190020 | 494 | 2.725 | 0.3419 | Yes | ||
21 | RYBP | 60746 | 500 | 2.714 | 0.3541 | Yes | ||
22 | ZBED4 | 770441 | 607 | 2.477 | 0.3597 | Yes | ||
23 | BMI1 | 3830026 2630204 | 662 | 2.375 | 0.3677 | Yes | ||
24 | TNFAIP3 | 2900142 | 665 | 2.367 | 0.3784 | Yes | ||
25 | KIF23 | 5570112 | 668 | 2.363 | 0.3891 | Yes | ||
26 | TBL1X | 6400524 | 726 | 2.280 | 0.3965 | Yes | ||
27 | TNFAIP8 | 2760551 | 740 | 2.248 | 0.4061 | Yes | ||
28 | SFRS3 | 770315 4230593 | 747 | 2.240 | 0.4160 | Yes | ||
29 | UGCG | 3420053 | 755 | 2.234 | 0.4259 | Yes | ||
30 | RAF1 | 1770600 | 782 | 2.195 | 0.4346 | Yes | ||
31 | TAF11 | 5720538 | 843 | 2.118 | 0.4410 | Yes | ||
32 | PHTF2 | 6590053 | 865 | 2.090 | 0.4495 | Yes | ||
33 | TLK2 | 1170161 | 908 | 2.029 | 0.4565 | Yes | ||
34 | ATP2A2 | 1090075 3990279 | 939 | 1.987 | 0.4640 | Yes | ||
35 | PRKCD | 770592 | 966 | 1.931 | 0.4714 | Yes | ||
36 | STX7 | 5910484 | 1016 | 1.871 | 0.4773 | Yes | ||
37 | RUNX1 | 3840711 | 1043 | 1.837 | 0.4844 | Yes | ||
38 | TLE1 | 540390 1580309 3710019 | 1108 | 1.770 | 0.4890 | Yes | ||
39 | SNX4 | 1980358 | 1109 | 1.769 | 0.4971 | Yes | ||
40 | MAPK14 | 5290731 | 1140 | 1.736 | 0.5034 | Yes | ||
41 | TOP2A | 360717 | 1165 | 1.703 | 0.5100 | Yes | ||
42 | CHD1 | 4590048 | 1176 | 1.692 | 0.5172 | Yes | ||
43 | HMGCR | 2630242 | 1208 | 1.661 | 0.5231 | Yes | ||
44 | CUL1 | 1990632 | 1241 | 1.620 | 0.5288 | Yes | ||
45 | EMG1 | 50286 380242 | 1316 | 1.532 | 0.5318 | Yes | ||
46 | KLF9 | 3840022 | 1323 | 1.526 | 0.5385 | Yes | ||
47 | SLC20A2 | 5700577 | 1415 | 1.427 | 0.5401 | Yes | ||
48 | CDR2 | 6200377 | 1479 | 1.366 | 0.5429 | Yes | ||
49 | RIPK1 | 3190025 | 1543 | 1.297 | 0.5454 | Yes | ||
50 | ATP6V1B2 | 4060528 | 1569 | 1.268 | 0.5499 | Yes | ||
51 | BLCAP | 3990253 | 1763 | 1.099 | 0.5445 | Yes | ||
52 | REV3L | 1090717 | 1823 | 1.065 | 0.5461 | Yes | ||
53 | TPST1 | 2570358 | 1853 | 1.043 | 0.5493 | Yes | ||
54 | AURKA | 780537 | 1880 | 1.026 | 0.5526 | Yes | ||
55 | SEC24B | 460717 3060040 | 1885 | 1.021 | 0.5571 | Yes | ||
56 | DICER1 | 540286 | 1920 | 1.001 | 0.5598 | Yes | ||
57 | RBM5 | 3520402 5270121 | 1935 | 0.998 | 0.5637 | Yes | ||
58 | RNF4 | 580286 1400152 | 1960 | 0.986 | 0.5669 | Yes | ||
59 | ARL4C | 1190279 | 2006 | 0.961 | 0.5688 | Yes | ||
60 | TNFRSF1A | 1090390 6520735 | 2015 | 0.957 | 0.5728 | Yes | ||
61 | RAD21 | 1990278 | 2041 | 0.945 | 0.5758 | Yes | ||
62 | MAT2A | 4070026 4730079 6020280 | 2051 | 0.938 | 0.5796 | Yes | ||
63 | FUS | 4760619 | 2058 | 0.935 | 0.5835 | Yes | ||
64 | CASP8 | 4850154 | 2097 | 0.907 | 0.5856 | Yes | ||
65 | DUSP11 | 1500088 4610280 | 2113 | 0.897 | 0.5889 | Yes | ||
66 | BHLHB2 | 7040603 | 2152 | 0.878 | 0.5909 | Yes | ||
67 | COIL | 4480408 | 2266 | 0.809 | 0.5885 | Yes | ||
68 | NCOA3 | 4540195 | 2284 | 0.802 | 0.5912 | Yes | ||
69 | DYRK1A | 3190181 | 2353 | 0.763 | 0.5910 | Yes | ||
70 | RHOB | 1500309 | 2372 | 0.756 | 0.5935 | Yes | ||
71 | PPP1R12A | 4070066 4590162 | 2393 | 0.748 | 0.5959 | Yes | ||
72 | PDCD10 | 4760500 | 2451 | 0.708 | 0.5960 | Yes | ||
73 | ADM | 4810121 | 2495 | 0.679 | 0.5968 | Yes | ||
74 | STX3 | 1190563 2640215 | 2558 | 0.650 | 0.5964 | No | ||
75 | SMURF2 | 1940161 | 2624 | 0.622 | 0.5957 | No | ||
76 | RAB11A | 5360079 | 2665 | 0.603 | 0.5963 | No | ||
77 | CDC6 | 4570296 5360600 | 2713 | 0.578 | 0.5964 | No | ||
78 | CASP3 | 6620397 | 2804 | 0.538 | 0.5940 | No | ||
79 | NTF3 | 5890131 | 2897 | 0.500 | 0.5913 | No | ||
80 | ACVR1B | 3610446 5570195 | 2980 | 0.471 | 0.5890 | No | ||
81 | IL4R | 2370520 | 3004 | 0.462 | 0.5898 | No | ||
82 | STRN3 | 1450093 6200685 | 3021 | 0.454 | 0.5910 | No | ||
83 | SQLE | 50180 940092 | 3048 | 0.445 | 0.5917 | No | ||
84 | CCNA2 | 5290075 | 3056 | 0.440 | 0.5933 | No | ||
85 | NFE2L2 | 2810619 3390162 | 3075 | 0.432 | 0.5943 | No | ||
86 | BRD8 | 1170463 2900075 4050397 6590332 | 3076 | 0.432 | 0.5963 | No | ||
87 | CBX3 | 1780592 3940008 | 3131 | 0.413 | 0.5952 | No | ||
88 | GBAS | 6760278 | 3227 | 0.383 | 0.5918 | No | ||
89 | CITED2 | 5670114 5130088 | 3236 | 0.379 | 0.5931 | No | ||
90 | NRIP1 | 3190039 | 3269 | 0.369 | 0.5931 | No | ||
91 | E2F3 | 50162 460180 | 3320 | 0.350 | 0.5920 | No | ||
92 | BMPR1A | 2190193 4060603 | 3376 | 0.335 | 0.5905 | No | ||
93 | KRIT1 | 2640500 4230435 4730184 | 3403 | 0.328 | 0.5906 | No | ||
94 | WEE1 | 3390070 | 3430 | 0.317 | 0.5907 | No | ||
95 | EIF4E | 1580403 70133 6380215 | 3604 | 0.264 | 0.5825 | No | ||
96 | BACH1 | 290195 | 3662 | 0.249 | 0.5805 | No | ||
97 | PDGFRA | 2940332 | 3701 | 0.239 | 0.5795 | No | ||
98 | CCNG1 | 870402 1500685 6110594 | 3857 | 0.206 | 0.5721 | No | ||
99 | AMD1 | 6290128 | 3943 | 0.188 | 0.5683 | No | ||
100 | ITGA6 | 3830129 | 3984 | 0.181 | 0.5670 | No | ||
101 | DUSP1 | 6860121 | 4217 | 0.144 | 0.5550 | No | ||
102 | PIP5K3 | 5360112 | 4307 | 0.134 | 0.5508 | No | ||
103 | MET | 2690348 | 4479 | 0.115 | 0.5420 | No | ||
104 | TOPBP1 | 6020333 | 4595 | 0.105 | 0.5362 | No | ||
105 | STAM | 3850008 4760441 | 4604 | 0.104 | 0.5363 | No | ||
106 | FYN | 2100468 4760520 4850687 | 4785 | 0.091 | 0.5269 | No | ||
107 | CSTF3 | 3850156 5570458 | 4848 | 0.086 | 0.5239 | No | ||
108 | PFTK1 | 1780181 | 4849 | 0.086 | 0.5243 | No | ||
109 | HMGB2 | 2640603 | 4856 | 0.085 | 0.5244 | No | ||
110 | SSH1 | 7000538 | 4944 | 0.081 | 0.5200 | No | ||
111 | STK24 | 6760484 | 4959 | 0.079 | 0.5196 | No | ||
112 | IDI1 | 1450736 | 4968 | 0.078 | 0.5195 | No | ||
113 | GNAI1 | 4560390 | 5227 | 0.065 | 0.5058 | No | ||
114 | STXBP3 | 780706 | 5319 | 0.062 | 0.5012 | No | ||
115 | PODXL | 130717 | 5384 | 0.059 | 0.4979 | No | ||
116 | TM4SF1 | 2570021 | 5898 | 0.042 | 0.4703 | No | ||
117 | TSPAN5 | 6770019 | 5950 | 0.041 | 0.4677 | No | ||
118 | FGF5 | 5270204 | 5954 | 0.041 | 0.4677 | No | ||
119 | EDG2 | 6290215 | 6059 | 0.038 | 0.4622 | No | ||
120 | RND3 | 940504 | 6107 | 0.036 | 0.4598 | No | ||
121 | DR1 | 5860750 | 6325 | 0.031 | 0.4482 | No | ||
122 | ZFAND5 | 6770673 | 6345 | 0.030 | 0.4473 | No | ||
123 | FHL5 | 430400 | 6449 | 0.028 | 0.4418 | No | ||
124 | SCHIP1 | 4560152 | 6555 | 0.026 | 0.4362 | No | ||
125 | TIPARP | 50397 | 6561 | 0.026 | 0.4361 | No | ||
126 | GATA2 | 6590280 | 6654 | 0.024 | 0.4312 | No | ||
127 | GEM | 5290082 | 6888 | 0.019 | 0.4186 | No | ||
128 | VEGFC | 5910494 | 6922 | 0.018 | 0.4169 | No | ||
129 | SLBP | 6220601 | 7013 | 0.016 | 0.4120 | No | ||
130 | MFAP1 | 6660092 | 7278 | 0.011 | 0.3977 | No | ||
131 | TLE4 | 1450064 1500519 | 7323 | 0.010 | 0.3954 | No | ||
132 | ARHGEF7 | 1690441 | 7397 | 0.009 | 0.3915 | No | ||
133 | XPO1 | 540707 | 7492 | 0.008 | 0.3864 | No | ||
134 | PLEKHC1 | 2650066 | 7620 | 0.005 | 0.3795 | No | ||
135 | SERTAD2 | 2810673 6840450 | 7658 | 0.005 | 0.3775 | No | ||
136 | PUM2 | 4200441 5910446 | 7693 | 0.004 | 0.3757 | No | ||
137 | PNN | 6650504 | 7831 | 0.002 | 0.3683 | No | ||
138 | RRS1 | 4560551 | 7840 | 0.002 | 0.3678 | No | ||
139 | NR2F2 | 3170609 3310577 | 8001 | -0.001 | 0.3591 | No | ||
140 | PDE4B | 4480121 | 8121 | -0.003 | 0.3527 | No | ||
141 | NUP153 | 7000452 | 8186 | -0.004 | 0.3492 | No | ||
142 | GAS1 | 2120504 | 8335 | -0.007 | 0.3412 | No | ||
143 | CKS2 | 1410156 | 8353 | -0.007 | 0.3403 | No | ||
144 | SAMD4A | 1170717 | 8358 | -0.007 | 0.3401 | No | ||
145 | YY1 | 6130451 | 8518 | -0.010 | 0.3315 | No | ||
146 | SATB2 | 2470181 | 8760 | -0.014 | 0.3185 | No | ||
147 | EPS8 | 7050204 | 8779 | -0.014 | 0.3176 | No | ||
148 | CTGF | 4540577 | 9137 | -0.020 | 0.2982 | No | ||
149 | IRS1 | 1190204 | 9291 | -0.023 | 0.2900 | No | ||
150 | SMAD7 | 430377 | 9316 | -0.023 | 0.2888 | No | ||
151 | STK38 | 7100114 | 9583 | -0.028 | 0.2745 | No | ||
152 | SS18 | 1940440 2900072 6900129 | 9629 | -0.029 | 0.2722 | No | ||
153 | POGZ | 870348 7040286 | 9837 | -0.033 | 0.2611 | No | ||
154 | POLE2 | 6110041 | 9924 | -0.035 | 0.2566 | No | ||
155 | GREM1 | 3940180 | 10175 | -0.041 | 0.2432 | No | ||
156 | BNIP2 | 1410475 6770088 | 10521 | -0.048 | 0.2246 | No | ||
157 | CDK7 | 2640451 | 11047 | -0.060 | 0.1964 | No | ||
158 | CNOT2 | 520546 2060397 4610543 5550113 | 11210 | -0.064 | 0.1878 | No | ||
159 | AGTR1 | 4780524 2680592 | 11368 | -0.070 | 0.1796 | No | ||
160 | MLX | 1770450 7040452 | 11603 | -0.077 | 0.1673 | No | ||
161 | CTDSP2 | 5340315 5690133 | 11662 | -0.079 | 0.1645 | No | ||
162 | ZFP36L2 | 510180 | 11959 | -0.091 | 0.1488 | No | ||
163 | HMGA2 | 2940121 3390647 5130279 6400136 | 11973 | -0.091 | 0.1485 | No | ||
164 | THBS1 | 4560494 430288 | 12132 | -0.098 | 0.1404 | No | ||
165 | NCK1 | 6200575 6510050 | 12187 | -0.100 | 0.1379 | No | ||
166 | BCAR3 | 1660717 | 12228 | -0.102 | 0.1362 | No | ||
167 | FOSL2 | 870044 1230427 6520433 | 12467 | -0.116 | 0.1238 | No | ||
168 | PKP4 | 3710400 5890097 | 12495 | -0.117 | 0.1228 | No | ||
169 | KIF2A | 3990286 6130575 | 12527 | -0.119 | 0.1217 | No | ||
170 | CXCL12 | 580546 4150750 4570068 | 12660 | -0.127 | 0.1151 | No | ||
171 | FZD7 | 7050706 | 12785 | -0.136 | 0.1090 | No | ||
172 | CYR61 | 1240408 5290026 4120452 6550008 | 12825 | -0.138 | 0.1075 | No | ||
173 | DLX2 | 2320438 4200673 | 12895 | -0.143 | 0.1044 | No | ||
174 | TUBGCP3 | 4920563 | 12924 | -0.145 | 0.1035 | No | ||
175 | ARID5B | 110403 | 12985 | -0.150 | 0.1010 | No | ||
176 | TRIM32 | 4150332 | 13079 | -0.157 | 0.0966 | No | ||
177 | CD2AP | 1940369 | 13118 | -0.159 | 0.0953 | No | ||
178 | SPRED2 | 510138 540195 | 13566 | -0.201 | 0.0719 | No | ||
179 | PAFAH1B1 | 4230333 6420121 6450066 | 13670 | -0.213 | 0.0673 | No | ||
180 | CENPA | 5080154 | 13738 | -0.221 | 0.0647 | No | ||
181 | DDIT4 | 2570408 | 13851 | -0.234 | 0.0596 | No | ||
182 | PPP2R5C | 3310121 6650672 | 13892 | -0.238 | 0.0586 | No | ||
183 | SPEN | 2060041 | 13919 | -0.241 | 0.0583 | No | ||
184 | UAP1 | 3060093 | 13936 | -0.243 | 0.0585 | No | ||
185 | CEBPD | 3360176 | 14049 | -0.258 | 0.0536 | No | ||
186 | RRAS2 | 6290170 | 14142 | -0.272 | 0.0498 | No | ||
187 | NFIL3 | 4070377 | 14188 | -0.278 | 0.0487 | No | ||
188 | HDHD1A | 6220328 | 14230 | -0.286 | 0.0478 | No | ||
189 | USP1 | 2760541 5690438 6220673 | 14322 | -0.302 | 0.0442 | No | ||
190 | HOXB2 | 6450592 | 14396 | -0.314 | 0.0417 | No | ||
191 | PPAP2B | 3190397 4730280 | 14538 | -0.339 | 0.0355 | No | ||
192 | UBTF | 4210450 6840403 | 14588 | -0.347 | 0.0345 | No | ||
193 | TRIB2 | 4120605 | 14714 | -0.373 | 0.0294 | No | ||
194 | FADD | 2360593 4210692 6520019 | 14796 | -0.392 | 0.0268 | No | ||
195 | CDYL | 4200142 4730397 6060400 | 14892 | -0.411 | 0.0235 | No | ||
196 | SWAP70 | 2810577 2850739 5130594 | 15100 | -0.466 | 0.0144 | No | ||
197 | HERPUD1 | 7100440 | 15120 | -0.470 | 0.0155 | No | ||
198 | PLK4 | 430162 5720110 | 15212 | -0.506 | 0.0129 | No | ||
199 | UBE2N | 520369 2900047 | 15283 | -0.527 | 0.0115 | No | ||
200 | CDK8 | 1050113 1190601 1780358 6110102 | 15335 | -0.544 | 0.0112 | No | ||
201 | ELF4 | 4850193 | 15357 | -0.552 | 0.0126 | No | ||
202 | ZHX3 | 460615 | 15422 | -0.576 | 0.0118 | No | ||
203 | NAP1L1 | 2510593 5900215 5090470 450079 4920280 | 15578 | -0.634 | 0.0063 | No | ||
204 | FBXO46 | 870273 | 15642 | -0.662 | 0.0059 | No | ||
205 | SIAH2 | 7210672 | 15668 | -0.672 | 0.0076 | No | ||
206 | HAS2 | 5360181 | 15725 | -0.694 | 0.0077 | No | ||
207 | PMP22 | 4010239 6550072 | 15763 | -0.715 | 0.0090 | No | ||
208 | SRF | 70139 2320039 | 15926 | -0.804 | 0.0039 | No | ||
209 | IFNGR2 | 1500288 2100176 | 16010 | -0.850 | 0.0033 | No | ||
210 | TWIST1 | 5130619 | 16286 | -1.005 | -0.0071 | No | ||
211 | TARDBP | 870390 2350093 | 16405 | -1.070 | -0.0086 | No | ||
212 | FZD2 | 6480154 | 16532 | -1.150 | -0.0102 | No | ||
213 | ARF6 | 3520026 | 16714 | -1.273 | -0.0142 | No | ||
214 | TRIP10 | 460438 | 16778 | -1.322 | -0.0115 | No | ||
215 | MTMR3 | 1050014 4920180 | 16991 | -1.493 | -0.0162 | No | ||
216 | USP10 | 2030736 2450333 | 17217 | -1.644 | -0.0209 | No | ||
217 | SMAD3 | 6450671 | 17349 | -1.764 | -0.0199 | No | ||
218 | LHFPL2 | 450020 | 17492 | -1.894 | -0.0189 | No | ||
219 | GNE | 6100465 | 17506 | -1.908 | -0.0109 | No | ||
220 | UNG | 3130110 6100364 | 17685 | -2.088 | -0.0110 | No | ||
221 | PTPN1 | 2650056 | 17742 | -2.174 | -0.0041 | No | ||
222 | PARP1 | 4780446 6400338 | 17812 | -2.259 | 0.0025 | No | ||
223 | IGF2BP3 | 2810161 4230338 | 18072 | -2.645 | 0.0006 | No | ||
224 | PHC2 | 1430433 | 18289 | -3.113 | 0.0031 | No | ||
225 | LSM2 | 510082 | 18314 | -3.185 | 0.0164 | No |