Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch_repos |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos |
Upregulated in class | absentNotch |
GeneSet | ET743_SARCOMA_DN |
Enrichment Score (ES) | 0.6034843 |
Normalized Enrichment Score (NES) | 1.8319131 |
Nominal p-value | 0.0 |
FDR q-value | 0.009465137 |
FWER p-Value | 0.051 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | LBR | 4540671 | 2 | 6.656 | 0.0305 | Yes | ||
2 | PRKACB | 4210170 | 9 | 6.062 | 0.0581 | Yes | ||
3 | HDAC2 | 4050433 | 20 | 5.359 | 0.0823 | Yes | ||
4 | EP400 | 3940722 | 25 | 5.156 | 0.1058 | Yes | ||
5 | SLC4A1AP | 3190576 | 50 | 4.754 | 0.1264 | Yes | ||
6 | RPP14 | 7040014 | 66 | 4.485 | 0.1462 | Yes | ||
7 | TMPO | 4050494 | 74 | 4.448 | 0.1663 | Yes | ||
8 | DDX20 | 3290348 | 79 | 4.358 | 0.1862 | Yes | ||
9 | HSPH1 | 1690017 | 84 | 4.292 | 0.2057 | Yes | ||
10 | SRPK2 | 6380341 | 87 | 4.282 | 0.2254 | Yes | ||
11 | GTF2H2 | 5130358 | 107 | 4.126 | 0.2433 | Yes | ||
12 | CCT4 | 6380161 | 117 | 4.044 | 0.2615 | Yes | ||
13 | RAP1B | 3710138 | 153 | 3.825 | 0.2772 | Yes | ||
14 | CCNH | 3190347 | 215 | 3.563 | 0.2903 | Yes | ||
15 | RAB1A | 2370671 | 252 | 3.405 | 0.3040 | Yes | ||
16 | DCK | 6900411 | 283 | 3.283 | 0.3175 | Yes | ||
17 | TBK1 | 5690338 | 291 | 3.258 | 0.3321 | Yes | ||
18 | PSMD14 | 5690593 | 317 | 3.166 | 0.3453 | Yes | ||
19 | SLC25A17 | 2100369 | 324 | 3.137 | 0.3595 | Yes | ||
20 | RABGAP1 | 5050397 | 326 | 3.128 | 0.3738 | Yes | ||
21 | PCNA | 940754 | 337 | 3.090 | 0.3875 | Yes | ||
22 | PSMA4 | 4560427 | 351 | 3.059 | 0.4009 | Yes | ||
23 | DDX21 | 6100446 | 409 | 2.918 | 0.4112 | Yes | ||
24 | AOF2 | 2060300 | 428 | 2.857 | 0.4234 | Yes | ||
25 | POLD3 | 6400278 | 499 | 2.715 | 0.4321 | Yes | ||
26 | MAP3K7 | 6040068 | 670 | 2.361 | 0.4337 | Yes | ||
27 | OSBPL9 | 2570373 | 703 | 2.316 | 0.4427 | Yes | ||
28 | SFRS3 | 770315 4230593 | 747 | 2.240 | 0.4507 | Yes | ||
29 | UBE2D2 | 4590671 6510446 | 761 | 2.229 | 0.4602 | Yes | ||
30 | PPP2R5E | 70671 2120056 | 776 | 2.202 | 0.4696 | Yes | ||
31 | BTG1 | 4200735 6040131 6200133 | 783 | 2.195 | 0.4794 | Yes | ||
32 | EIF4B | 5390563 5270577 | 844 | 2.116 | 0.4859 | Yes | ||
33 | ZDHHC5 | 1690711 | 876 | 2.080 | 0.4938 | Yes | ||
34 | RABGGTB | 3120037 | 885 | 2.067 | 0.5028 | Yes | ||
35 | FNTA | 70059 | 1075 | 1.808 | 0.5009 | Yes | ||
36 | STAU1 | 2320494 | 1112 | 1.767 | 0.5071 | Yes | ||
37 | MAPK14 | 5290731 | 1140 | 1.736 | 0.5136 | Yes | ||
38 | MCTS1 | 6130133 | 1148 | 1.732 | 0.5212 | Yes | ||
39 | TOP2A | 360717 | 1165 | 1.703 | 0.5282 | Yes | ||
40 | SIRT1 | 1190731 | 1190 | 1.676 | 0.5346 | Yes | ||
41 | NET1 | 2900707 | 1228 | 1.643 | 0.5402 | Yes | ||
42 | UBE2D3 | 3190452 | 1252 | 1.609 | 0.5463 | Yes | ||
43 | TXNRD1 | 6590446 | 1345 | 1.508 | 0.5483 | Yes | ||
44 | CRLF3 | 6620019 | 1414 | 1.430 | 0.5512 | Yes | ||
45 | RBM17 | 870592 | 1425 | 1.417 | 0.5572 | Yes | ||
46 | OGT | 2360131 4610333 | 1542 | 1.298 | 0.5568 | Yes | ||
47 | RIPK1 | 3190025 | 1543 | 1.297 | 0.5628 | Yes | ||
48 | PJA2 | 430537 | 1544 | 1.296 | 0.5688 | Yes | ||
49 | SUPV3L1 | 1170072 | 1612 | 1.229 | 0.5708 | Yes | ||
50 | USP3 | 2060332 | 1681 | 1.162 | 0.5725 | Yes | ||
51 | PSME3 | 2810537 | 1687 | 1.158 | 0.5775 | Yes | ||
52 | MRPL15 | 360390 | 1735 | 1.128 | 0.5802 | Yes | ||
53 | SIRPA | 130465 5700332 | 1753 | 1.108 | 0.5843 | Yes | ||
54 | PRIM2A | 7000692 | 1791 | 1.081 | 0.5873 | Yes | ||
55 | ELOVL6 | 5340746 | 1825 | 1.064 | 0.5904 | Yes | ||
56 | CDC5L | 3130446 3390025 6400204 | 1852 | 1.043 | 0.5938 | Yes | ||
57 | AURKA | 780537 | 1880 | 1.026 | 0.5971 | Yes | ||
58 | PPP1CC | 6380300 2510647 | 1943 | 0.993 | 0.5983 | Yes | ||
59 | MAT2A | 4070026 4730079 6020280 | 2051 | 0.938 | 0.5968 | Yes | ||
60 | TNFSF5IP1 | 2060095 | 2066 | 0.929 | 0.6003 | Yes | ||
61 | YWHAE | 5310435 | 2086 | 0.911 | 0.6035 | Yes | ||
62 | CDK5R1 | 3870161 | 2238 | 0.826 | 0.5991 | No | ||
63 | GTF2B | 6860685 | 2263 | 0.810 | 0.6015 | No | ||
64 | PSMC6 | 2810021 | 2329 | 0.776 | 0.6016 | No | ||
65 | MCM3 | 5570068 | 2610 | 0.627 | 0.5893 | No | ||
66 | TCERG1 | 2350551 4540397 5220746 | 2638 | 0.615 | 0.5906 | No | ||
67 | XBP1 | 3840594 | 2744 | 0.564 | 0.5875 | No | ||
68 | CLCN7 | 2970095 | 2767 | 0.555 | 0.5889 | No | ||
69 | BCL2L1 | 1580452 4200152 5420484 | 2821 | 0.530 | 0.5884 | No | ||
70 | BIRC2 | 2940435 4730020 | 2884 | 0.505 | 0.5874 | No | ||
71 | GABPB2 | 6130450 7050735 | 3050 | 0.444 | 0.5805 | No | ||
72 | CCNA2 | 5290075 | 3056 | 0.440 | 0.5822 | No | ||
73 | SRRM2 | 2940746 6350253 | 3092 | 0.428 | 0.5823 | No | ||
74 | STK17B | 130091 | 3198 | 0.393 | 0.5784 | No | ||
75 | EML4 | 5700373 | 3202 | 0.390 | 0.5801 | No | ||
76 | FBXL3 | 5910142 | 3266 | 0.371 | 0.5784 | No | ||
77 | MYC | 380541 4670170 | 3372 | 0.337 | 0.5742 | No | ||
78 | WEE1 | 3390070 | 3430 | 0.317 | 0.5726 | No | ||
79 | FAF1 | 2450717 2510121 4730156 | 3435 | 0.315 | 0.5738 | No | ||
80 | USP12 | 6130735 6620280 | 3458 | 0.309 | 0.5740 | No | ||
81 | FNDC3A | 2690097 3290044 | 3635 | 0.255 | 0.5656 | No | ||
82 | ARFGEF2 | 5550500 | 3804 | 0.216 | 0.5575 | No | ||
83 | LUZP1 | 940075 4280458 6180070 | 3827 | 0.213 | 0.5573 | No | ||
84 | MRPS35 | 2370603 4070551 | 3850 | 0.207 | 0.5571 | No | ||
85 | CDC23 | 3190593 | 3954 | 0.186 | 0.5523 | No | ||
86 | PSMB1 | 2940402 | 3957 | 0.186 | 0.5531 | No | ||
87 | PAFAH2 | 3140451 5720593 6510014 | 4248 | 0.141 | 0.5380 | No | ||
88 | PTPRK | 1450433 2640142 | 4579 | 0.106 | 0.5206 | No | ||
89 | SSFA2 | 3870133 | 4773 | 0.091 | 0.5105 | No | ||
90 | FYN | 2100468 4760520 4850687 | 4785 | 0.091 | 0.5103 | No | ||
91 | HSPA1L | 4010538 | 4837 | 0.087 | 0.5080 | No | ||
92 | RCOR1 | 5360717 | 4910 | 0.082 | 0.5044 | No | ||
93 | GGPS1 | 840128 2320215 | 4984 | 0.077 | 0.5008 | No | ||
94 | ACSL3 | 3140195 | 5101 | 0.072 | 0.4949 | No | ||
95 | RAD23B | 2190671 | 5234 | 0.065 | 0.4880 | No | ||
96 | CYHR1 | 940609 2810463 3190332 3290692 4280411 | 5349 | 0.061 | 0.4821 | No | ||
97 | GOPC | 6620400 | 5371 | 0.060 | 0.4812 | No | ||
98 | CDC42BPA | 840671 | 5661 | 0.050 | 0.4658 | No | ||
99 | GDI2 | 2370068 | 5706 | 0.048 | 0.4636 | No | ||
100 | CSNK2A1 | 1580577 | 5807 | 0.045 | 0.4584 | No | ||
101 | CDC25C | 2570673 4760161 6520707 | 6003 | 0.040 | 0.4480 | No | ||
102 | CFLAR | 2320605 6180440 | 6118 | 0.036 | 0.4420 | No | ||
103 | RAB6A | 3840463 4780731 | 6666 | 0.023 | 0.4124 | No | ||
104 | VEGFC | 5910494 | 6922 | 0.018 | 0.3986 | No | ||
105 | RAB5A | 6520324 | 7143 | 0.014 | 0.3867 | No | ||
106 | SPRY2 | 5860184 | 7168 | 0.014 | 0.3855 | No | ||
107 | MFAP1 | 6660092 | 7278 | 0.011 | 0.3796 | No | ||
108 | ATG5 | 6200433 5360324 | 7586 | 0.006 | 0.3630 | No | ||
109 | BIRC6 | 70148 | 7681 | 0.004 | 0.3579 | No | ||
110 | CRK | 1230162 4780128 | 7694 | 0.004 | 0.3573 | No | ||
111 | EPS15 | 4200215 | 7770 | 0.003 | 0.3532 | No | ||
112 | TIAM2 | 360195 | 7777 | 0.003 | 0.3529 | No | ||
113 | XRCC5 | 7100286 | 7892 | 0.001 | 0.3467 | No | ||
114 | KIF11 | 5390139 | 7948 | -0.000 | 0.3437 | No | ||
115 | MAP3K4 | 5720041 | 8324 | -0.006 | 0.3234 | No | ||
116 | SAMD4A | 1170717 | 8358 | -0.007 | 0.3217 | No | ||
117 | EPS8 | 7050204 | 8779 | -0.014 | 0.2989 | No | ||
118 | JAG1 | 3440390 | 8849 | -0.015 | 0.2952 | No | ||
119 | CTGF | 4540577 | 9137 | -0.020 | 0.2798 | No | ||
120 | NCOA6 | 1780333 6450110 | 9545 | -0.027 | 0.2578 | No | ||
121 | MTIF2 | 2260270 | 9575 | -0.028 | 0.2563 | No | ||
122 | ATF1 | 4570142 5550095 | 9619 | -0.029 | 0.2541 | No | ||
123 | SMARCA5 | 6620050 | 9663 | -0.030 | 0.2519 | No | ||
124 | MAPKAPK5 | 2510601 | 9831 | -0.033 | 0.2430 | No | ||
125 | NPAS2 | 770670 | 9849 | -0.033 | 0.2423 | No | ||
126 | TRIM24 | 7050670 | 9851 | -0.034 | 0.2424 | No | ||
127 | FOSL1 | 430021 | 10317 | -0.043 | 0.2173 | No | ||
128 | GTF2H1 | 2570746 2650148 | 10462 | -0.047 | 0.2097 | No | ||
129 | FZD1 | 3140215 | 10538 | -0.048 | 0.2059 | No | ||
130 | FBXL7 | 6620711 | 10661 | -0.051 | 0.1995 | No | ||
131 | CDH11 | 1230133 2100180 4610110 | 10844 | -0.055 | 0.1899 | No | ||
132 | IPO7 | 2190746 | 10918 | -0.057 | 0.1862 | No | ||
133 | TRIP4 | 630072 | 11036 | -0.060 | 0.1801 | No | ||
134 | CDK7 | 2640451 | 11047 | -0.060 | 0.1798 | No | ||
135 | MRPL1 | 430626 3130129 5220152 | 11258 | -0.066 | 0.1687 | No | ||
136 | PRKD3 | 5220520 5890519 | 11261 | -0.066 | 0.1689 | No | ||
137 | USP8 | 2640347 3840451 6100672 | 11381 | -0.070 | 0.1628 | No | ||
138 | TDG | 2900358 2940079 | 11399 | -0.071 | 0.1622 | No | ||
139 | CXXC5 | 840010 | 11461 | -0.073 | 0.1592 | No | ||
140 | RBM27 | 4050603 | 11557 | -0.076 | 0.1544 | No | ||
141 | JMJD1C | 940575 2120025 | 11594 | -0.077 | 0.1528 | No | ||
142 | NMI | 520270 | 11645 | -0.079 | 0.1504 | No | ||
143 | THRAP3 | 6180309 | 11738 | -0.082 | 0.1458 | No | ||
144 | NBN | 730538 2470619 4780594 | 12073 | -0.095 | 0.1281 | No | ||
145 | NUFIP1 | 6350241 | 12178 | -0.100 | 0.1230 | No | ||
146 | B4GALT5 | 1230692 | 12700 | -0.129 | 0.0953 | No | ||
147 | OSBP | 5390471 | 12793 | -0.136 | 0.0909 | No | ||
148 | PLK1 | 1780369 2640121 | 12890 | -0.143 | 0.0863 | No | ||
149 | RCC1 | 2480358 | 12929 | -0.146 | 0.0850 | No | ||
150 | CRSP6 | 2940358 | 12979 | -0.150 | 0.0830 | No | ||
151 | HS3ST3B1 | 380040 | 13244 | -0.169 | 0.0694 | No | ||
152 | CORO1C | 4570397 | 13442 | -0.186 | 0.0596 | No | ||
153 | PLAG1 | 1450142 3870139 6520039 | 13519 | -0.194 | 0.0564 | No | ||
154 | BUB1 | 5390270 | 13543 | -0.197 | 0.0560 | No | ||
155 | HSPE1 | 3170438 | 13651 | -0.210 | 0.0512 | No | ||
156 | PDGFB | 3060440 6370008 | 13712 | -0.217 | 0.0489 | No | ||
157 | RNF14 | 50402 1340041 6370687 | 14329 | -0.302 | 0.0169 | No | ||
158 | PHF6 | 3120632 3990041 | 14389 | -0.313 | 0.0151 | No | ||
159 | BLZF1 | 630088 | 14439 | -0.321 | 0.0139 | No | ||
160 | SNIP1 | 5360092 | 14451 | -0.323 | 0.0148 | No | ||
161 | EGFR | 4920138 6480521 | 14611 | -0.351 | 0.0078 | No | ||
162 | JMJD2B | 6350372 6400471 | 14776 | -0.387 | 0.0007 | No | ||
163 | FADD | 2360593 4210692 6520019 | 14796 | -0.392 | 0.0015 | No | ||
164 | ANLN | 1780113 2470537 6840047 | 14839 | -0.399 | 0.0010 | No | ||
165 | UBN1 | 5900195 | 15041 | -0.451 | -0.0078 | No | ||
166 | ERCC3 | 6900008 | 15060 | -0.456 | -0.0067 | No | ||
167 | EIF3S10 | 1190079 3840176 | 15098 | -0.465 | -0.0066 | No | ||
168 | MTMR4 | 4540524 | 15156 | -0.484 | -0.0074 | No | ||
169 | DLG5 | 450215 | 15406 | -0.570 | -0.0183 | No | ||
170 | PKN2 | 940746 2350168 | 15423 | -0.577 | -0.0165 | No | ||
171 | PSMA5 | 5390537 | 15477 | -0.596 | -0.0166 | No | ||
172 | PSMC2 | 7040010 | 15750 | -0.707 | -0.0282 | No | ||
173 | TOP1 | 770471 4060632 6650324 | 15975 | -0.831 | -0.0365 | No | ||
174 | SFRS9 | 3800047 | 16089 | -0.890 | -0.0385 | No | ||
175 | ADSL | 5570484 | 16114 | -0.908 | -0.0356 | No | ||
176 | DNAJA2 | 2630253 6860358 | 16201 | -0.960 | -0.0359 | No | ||
177 | KIAA0859 | 510497 770722 1340687 6840711 | 16202 | -0.963 | -0.0315 | No | ||
178 | TARDBP | 870390 2350093 | 16405 | -1.070 | -0.0375 | No | ||
179 | ARHGEF2 | 3360577 | 16715 | -1.274 | -0.0484 | No | ||
180 | SON | 3120148 5860239 7040403 | 16751 | -1.303 | -0.0443 | No | ||
181 | PANX1 | 6550632 | 16858 | -1.406 | -0.0436 | No | ||
182 | SLC2A1 | 2100609 | 16940 | -1.465 | -0.0412 | No | ||
183 | BAG2 | 2900324 | 17077 | -1.540 | -0.0415 | No | ||
184 | ARFGAP1 | 4780364 5390358 | 17246 | -1.676 | -0.0429 | No | ||
185 | RBM14 | 5340731 5690315 | 17264 | -1.692 | -0.0360 | No | ||
186 | ZDHHC16 | 4230390 | 17297 | -1.722 | -0.0299 | No | ||
187 | UBE2C | 6130017 | 17457 | -1.873 | -0.0299 | No | ||
188 | LHFPL2 | 450020 | 17492 | -1.894 | -0.0230 | No | ||
189 | HIST1H4C | 5570528 | 17659 | -2.061 | -0.0225 | No | ||
190 | ARPC5L | 1090148 | 17660 | -2.061 | -0.0130 | No | ||
191 | HSPA8 | 2120315 1050132 6550746 | 17686 | -2.090 | -0.0047 | No | ||
192 | HIST1H4B | 4210524 | 17856 | -2.317 | -0.0032 | No | ||
193 | BUB3 | 3170546 | 17989 | -2.521 | 0.0012 | No | ||
194 | MID1IP1 | 2570739 | 18117 | -2.723 | 0.0068 | No | ||
195 | WNT5B | 5080162 | 18545 | -4.385 | 0.0039 | No |