Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch_repos |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos |
Upregulated in class | absentNotch |
GeneSet | ET743_SARCOMA_72HRS_DN |
Enrichment Score (ES) | 0.60076934 |
Normalized Enrichment Score (NES) | 1.8103333 |
Nominal p-value | 0.0 |
FDR q-value | 0.013162311 |
FWER p-Value | 0.076 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | LBR | 4540671 | 2 | 6.656 | 0.0339 | Yes | ||
2 | HDAC2 | 4050433 | 20 | 5.359 | 0.0604 | Yes | ||
3 | SLC4A1AP | 3190576 | 50 | 4.754 | 0.0831 | Yes | ||
4 | SMAD4 | 5670519 | 72 | 4.465 | 0.1048 | Yes | ||
5 | TMPO | 4050494 | 74 | 4.448 | 0.1275 | Yes | ||
6 | DDX20 | 3290348 | 79 | 4.358 | 0.1495 | Yes | ||
7 | HSPH1 | 1690017 | 84 | 4.292 | 0.1713 | Yes | ||
8 | SRPK2 | 6380341 | 87 | 4.282 | 0.1931 | Yes | ||
9 | GTF2H2 | 5130358 | 107 | 4.126 | 0.2131 | Yes | ||
10 | CCT4 | 6380161 | 117 | 4.044 | 0.2333 | Yes | ||
11 | RAP1B | 3710138 | 153 | 3.825 | 0.2510 | Yes | ||
12 | CCNH | 3190347 | 215 | 3.563 | 0.2659 | Yes | ||
13 | EMP1 | 4120438 | 220 | 3.541 | 0.2837 | Yes | ||
14 | RAB1A | 2370671 | 252 | 3.405 | 0.2995 | Yes | ||
15 | TBK1 | 5690338 | 291 | 3.258 | 0.3141 | Yes | ||
16 | SLC25A17 | 2100369 | 324 | 3.137 | 0.3284 | Yes | ||
17 | RABGAP1 | 5050397 | 326 | 3.128 | 0.3443 | Yes | ||
18 | PCNA | 940754 | 337 | 3.090 | 0.3596 | Yes | ||
19 | PSMA4 | 4560427 | 351 | 3.059 | 0.3745 | Yes | ||
20 | PIK3C3 | 6590717 | 386 | 2.975 | 0.3878 | Yes | ||
21 | DDX21 | 6100446 | 409 | 2.918 | 0.4016 | Yes | ||
22 | POLD3 | 6400278 | 499 | 2.715 | 0.4106 | Yes | ||
23 | PPP2CB | 5570593 | 503 | 2.711 | 0.4243 | Yes | ||
24 | EXOC2 | 3190132 | 520 | 2.677 | 0.4371 | Yes | ||
25 | MAP3K7 | 6040068 | 670 | 2.361 | 0.4411 | Yes | ||
26 | UBE2D2 | 4590671 6510446 | 761 | 2.229 | 0.4477 | Yes | ||
27 | PPP2R5E | 70671 2120056 | 776 | 2.202 | 0.4581 | Yes | ||
28 | EIF4B | 5390563 5270577 | 844 | 2.116 | 0.4653 | Yes | ||
29 | ZDHHC5 | 1690711 | 876 | 2.080 | 0.4743 | Yes | ||
30 | RABGGTB | 3120037 | 885 | 2.067 | 0.4844 | Yes | ||
31 | ATP2A2 | 1090075 3990279 | 939 | 1.987 | 0.4917 | Yes | ||
32 | FNTA | 70059 | 1075 | 1.808 | 0.4936 | Yes | ||
33 | MAPK14 | 5290731 | 1140 | 1.736 | 0.4990 | Yes | ||
34 | MCTS1 | 6130133 | 1148 | 1.732 | 0.5075 | Yes | ||
35 | TOP2A | 360717 | 1165 | 1.703 | 0.5153 | Yes | ||
36 | PSMD12 | 730044 | 1178 | 1.690 | 0.5233 | Yes | ||
37 | SIRT1 | 1190731 | 1190 | 1.676 | 0.5313 | Yes | ||
38 | UBE2D3 | 3190452 | 1252 | 1.609 | 0.5362 | Yes | ||
39 | TXNRD1 | 6590446 | 1345 | 1.508 | 0.5389 | Yes | ||
40 | RBM17 | 870592 | 1425 | 1.417 | 0.5419 | Yes | ||
41 | GNL2 | 6620022 | 1483 | 1.362 | 0.5458 | Yes | ||
42 | OGT | 2360131 4610333 | 1542 | 1.298 | 0.5493 | Yes | ||
43 | RIPK1 | 3190025 | 1543 | 1.297 | 0.5559 | Yes | ||
44 | PJA2 | 430537 | 1544 | 1.296 | 0.5625 | Yes | ||
45 | SUPV3L1 | 1170072 | 1612 | 1.229 | 0.5652 | Yes | ||
46 | SNRPG | 2340551 | 1655 | 1.180 | 0.5689 | Yes | ||
47 | USP3 | 2060332 | 1681 | 1.162 | 0.5735 | Yes | ||
48 | MRPL15 | 360390 | 1735 | 1.128 | 0.5764 | Yes | ||
49 | SIRPA | 130465 5700332 | 1753 | 1.108 | 0.5811 | Yes | ||
50 | PRIM2A | 7000692 | 1791 | 1.081 | 0.5847 | Yes | ||
51 | ELOVL6 | 5340746 | 1825 | 1.064 | 0.5883 | Yes | ||
52 | CDC5L | 3130446 3390025 6400204 | 1852 | 1.043 | 0.5922 | Yes | ||
53 | RPS7 | 6860113 | 1867 | 1.033 | 0.5968 | Yes | ||
54 | PPP1CC | 6380300 2510647 | 1943 | 0.993 | 0.5978 | Yes | ||
55 | MAT2A | 4070026 4730079 6020280 | 2051 | 0.938 | 0.5968 | Yes | ||
56 | TNFSF5IP1 | 2060095 | 2066 | 0.929 | 0.6008 | Yes | ||
57 | GTF2B | 6860685 | 2263 | 0.810 | 0.5943 | No | ||
58 | PSMC6 | 2810021 | 2329 | 0.776 | 0.5947 | No | ||
59 | MRPL35 | 1990671 | 2574 | 0.644 | 0.5848 | No | ||
60 | MCM3 | 5570068 | 2610 | 0.627 | 0.5861 | No | ||
61 | TCERG1 | 2350551 4540397 5220746 | 2638 | 0.615 | 0.5878 | No | ||
62 | XBP1 | 3840594 | 2744 | 0.564 | 0.5850 | No | ||
63 | CLCN7 | 2970095 | 2767 | 0.555 | 0.5866 | No | ||
64 | BCL2L1 | 1580452 4200152 5420484 | 2821 | 0.530 | 0.5865 | No | ||
65 | BIRC2 | 2940435 4730020 | 2884 | 0.505 | 0.5857 | No | ||
66 | GABPB2 | 6130450 7050735 | 3050 | 0.444 | 0.5790 | No | ||
67 | CCNA2 | 5290075 | 3056 | 0.440 | 0.5810 | No | ||
68 | STK17B | 130091 | 3198 | 0.393 | 0.5754 | No | ||
69 | EML4 | 5700373 | 3202 | 0.390 | 0.5772 | No | ||
70 | FBXL3 | 5910142 | 3266 | 0.371 | 0.5757 | No | ||
71 | MYC | 380541 4670170 | 3372 | 0.337 | 0.5717 | No | ||
72 | WEE1 | 3390070 | 3430 | 0.317 | 0.5702 | No | ||
73 | USP12 | 6130735 6620280 | 3458 | 0.309 | 0.5703 | No | ||
74 | FNDC3A | 2690097 3290044 | 3635 | 0.255 | 0.5621 | No | ||
75 | ARFGEF2 | 5550500 | 3804 | 0.216 | 0.5541 | No | ||
76 | CDC23 | 3190593 | 3954 | 0.186 | 0.5470 | No | ||
77 | PSMB1 | 2940402 | 3957 | 0.186 | 0.5478 | No | ||
78 | SSFA2 | 3870133 | 4773 | 0.091 | 0.5041 | No | ||
79 | HSPA1L | 4010538 | 4837 | 0.087 | 0.5012 | No | ||
80 | GGPS1 | 840128 2320215 | 4984 | 0.077 | 0.4936 | No | ||
81 | ACSL3 | 3140195 | 5101 | 0.072 | 0.4877 | No | ||
82 | CYHR1 | 940609 2810463 3190332 3290692 4280411 | 5349 | 0.061 | 0.4746 | No | ||
83 | GOPC | 6620400 | 5371 | 0.060 | 0.4738 | No | ||
84 | GDI2 | 2370068 | 5706 | 0.048 | 0.4559 | No | ||
85 | CDC25C | 2570673 4760161 6520707 | 6003 | 0.040 | 0.4401 | No | ||
86 | CFLAR | 2320605 6180440 | 6118 | 0.036 | 0.4341 | No | ||
87 | VEGFC | 5910494 | 6922 | 0.018 | 0.3907 | No | ||
88 | RAB5A | 6520324 | 7143 | 0.014 | 0.3788 | No | ||
89 | SPRY2 | 5860184 | 7168 | 0.014 | 0.3776 | No | ||
90 | MFAP1 | 6660092 | 7278 | 0.011 | 0.3717 | No | ||
91 | SEH1L | 4590563 | 7546 | 0.007 | 0.3573 | No | ||
92 | ATG5 | 6200433 5360324 | 7586 | 0.006 | 0.3552 | No | ||
93 | BIRC6 | 70148 | 7681 | 0.004 | 0.3502 | No | ||
94 | CRK | 1230162 4780128 | 7694 | 0.004 | 0.3495 | No | ||
95 | EPS15 | 4200215 | 7770 | 0.003 | 0.3455 | No | ||
96 | TIAM2 | 360195 | 7777 | 0.003 | 0.3452 | No | ||
97 | XRCC5 | 7100286 | 7892 | 0.001 | 0.3390 | No | ||
98 | EPS8 | 7050204 | 8779 | -0.014 | 0.2910 | No | ||
99 | LYN | 6040600 | 8816 | -0.015 | 0.2892 | No | ||
100 | JAG1 | 3440390 | 8849 | -0.015 | 0.2875 | No | ||
101 | CTGF | 4540577 | 9137 | -0.020 | 0.2721 | No | ||
102 | NCOA6 | 1780333 6450110 | 9545 | -0.027 | 0.2501 | No | ||
103 | MTIF2 | 2260270 | 9575 | -0.028 | 0.2487 | No | ||
104 | SMARCA5 | 6620050 | 9663 | -0.030 | 0.2441 | No | ||
105 | CPT1A | 6350093 | 10027 | -0.038 | 0.2247 | No | ||
106 | FOSL1 | 430021 | 10317 | -0.043 | 0.2092 | No | ||
107 | GTF2H1 | 2570746 2650148 | 10462 | -0.047 | 0.2016 | No | ||
108 | FZD1 | 3140215 | 10538 | -0.048 | 0.1978 | No | ||
109 | FBXL7 | 6620711 | 10661 | -0.051 | 0.1915 | No | ||
110 | CDH11 | 1230133 2100180 4610110 | 10844 | -0.055 | 0.1819 | No | ||
111 | IPO7 | 2190746 | 10918 | -0.057 | 0.1782 | No | ||
112 | CDK7 | 2640451 | 11047 | -0.060 | 0.1716 | No | ||
113 | IL1RL1 | 3990224 6020347 | 11246 | -0.065 | 0.1612 | No | ||
114 | MRPL1 | 430626 3130129 5220152 | 11258 | -0.066 | 0.1609 | No | ||
115 | PRKD3 | 5220520 5890519 | 11261 | -0.066 | 0.1612 | No | ||
116 | TDG | 2900358 2940079 | 11399 | -0.071 | 0.1541 | No | ||
117 | CXXC5 | 840010 | 11461 | -0.073 | 0.1512 | No | ||
118 | RBM27 | 4050603 | 11557 | -0.076 | 0.1464 | No | ||
119 | ACTL6A | 5220543 6290541 2450093 4590332 5270722 | 11564 | -0.076 | 0.1465 | No | ||
120 | THRAP3 | 6180309 | 11738 | -0.082 | 0.1375 | No | ||
121 | NUFIP1 | 6350241 | 12178 | -0.100 | 0.1142 | No | ||
122 | B4GALT5 | 1230692 | 12700 | -0.129 | 0.0867 | No | ||
123 | RCC1 | 2480358 | 12929 | -0.146 | 0.0750 | No | ||
124 | CRSP6 | 2940358 | 12979 | -0.150 | 0.0732 | No | ||
125 | HS3ST3B1 | 380040 | 13244 | -0.169 | 0.0597 | No | ||
126 | CORO1C | 4570397 | 13442 | -0.186 | 0.0500 | No | ||
127 | PLAG1 | 1450142 3870139 6520039 | 13519 | -0.194 | 0.0469 | No | ||
128 | BUB1 | 5390270 | 13543 | -0.197 | 0.0466 | No | ||
129 | HSPE1 | 3170438 | 13651 | -0.210 | 0.0419 | No | ||
130 | PDGFB | 3060440 6370008 | 13712 | -0.217 | 0.0397 | No | ||
131 | RNF14 | 50402 1340041 6370687 | 14329 | -0.302 | 0.0079 | No | ||
132 | BLZF1 | 630088 | 14439 | -0.321 | 0.0036 | No | ||
133 | SNIP1 | 5360092 | 14451 | -0.323 | 0.0047 | No | ||
134 | GCNT1 | 940129 1780215 2370253 | 14515 | -0.334 | 0.0030 | No | ||
135 | PAPPA | 4230463 | 14662 | -0.361 | -0.0031 | No | ||
136 | JMJD2B | 6350372 6400471 | 14776 | -0.387 | -0.0072 | No | ||
137 | FADD | 2360593 4210692 6520019 | 14796 | -0.392 | -0.0063 | No | ||
138 | ANLN | 1780113 2470537 6840047 | 14839 | -0.399 | -0.0065 | No | ||
139 | ERCC3 | 6900008 | 15060 | -0.456 | -0.0161 | No | ||
140 | EIF3S10 | 1190079 3840176 | 15098 | -0.465 | -0.0157 | No | ||
141 | MTMR4 | 4540524 | 15156 | -0.484 | -0.0163 | No | ||
142 | CHST2 | 3180682 | 15161 | -0.485 | -0.0141 | No | ||
143 | FAS | 4480112 6110040 | 15168 | -0.488 | -0.0119 | No | ||
144 | DLG5 | 450215 | 15406 | -0.570 | -0.0218 | No | ||
145 | PSMA5 | 5390537 | 15477 | -0.596 | -0.0226 | No | ||
146 | TOP1 | 770471 4060632 6650324 | 15975 | -0.831 | -0.0453 | No | ||
147 | SFRS9 | 3800047 | 16089 | -0.890 | -0.0468 | No | ||
148 | ADSL | 5570484 | 16114 | -0.908 | -0.0435 | No | ||
149 | DNAJA2 | 2630253 6860358 | 16201 | -0.960 | -0.0432 | No | ||
150 | KIAA0859 | 510497 770722 1340687 6840711 | 16202 | -0.963 | -0.0383 | No | ||
151 | TARDBP | 870390 2350093 | 16405 | -1.070 | -0.0438 | No | ||
152 | ARHGEF2 | 3360577 | 16715 | -1.274 | -0.0540 | No | ||
153 | SON | 3120148 5860239 7040403 | 16751 | -1.303 | -0.0493 | No | ||
154 | PANX1 | 6550632 | 16858 | -1.406 | -0.0478 | No | ||
155 | SLC2A1 | 2100609 | 16940 | -1.465 | -0.0447 | No | ||
156 | BAG2 | 2900324 | 17077 | -1.540 | -0.0442 | No | ||
157 | FKBP1A | 2450368 | 17092 | -1.554 | -0.0371 | No | ||
158 | ARFGAP1 | 4780364 5390358 | 17246 | -1.676 | -0.0368 | No | ||
159 | RBM14 | 5340731 5690315 | 17264 | -1.692 | -0.0290 | No | ||
160 | ZDHHC16 | 4230390 | 17297 | -1.722 | -0.0220 | No | ||
161 | UBE2C | 6130017 | 17457 | -1.873 | -0.0210 | No | ||
162 | LHFPL2 | 450020 | 17492 | -1.894 | -0.0132 | No | ||
163 | HSPA8 | 2120315 1050132 6550746 | 17686 | -2.090 | -0.0130 | No | ||
164 | BUB3 | 3170546 | 17989 | -2.521 | -0.0164 | No | ||
165 | MID1IP1 | 2570739 | 18117 | -2.723 | -0.0094 | No | ||
166 | GIPC1 | 4590348 5570438 5900707 | 18121 | -2.726 | 0.0044 | No | ||
167 | WNT5B | 5080162 | 18545 | -4.385 | 0.0038 | No |