DatasetSet_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls
#absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls
#absentNotch_versus_truncNotch_repos
Phenotypephenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos
Upregulated in classabsentNotch
GeneSetET743_SARCOMA_72HRS_DN
Enrichment Score (ES)0.60076934
Normalized Enrichment Score (NES)1.8103333
Nominal p-value0.0
FDR q-value0.013162311
FWER p-Value0.076
Table: GSEA Results Summary



Fig 1: Enrichment plot: ET743_SARCOMA_72HRS_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1LBR454067126.6560.0339Yes
2HDAC24050433205.3590.0604Yes
3SLC4A1AP3190576504.7540.0831Yes
4SMAD45670519724.4650.1048Yes
5TMPO4050494744.4480.1275Yes
6DDX203290348794.3580.1495Yes
7HSPH11690017844.2920.1713Yes
8SRPK26380341874.2820.1931Yes
9GTF2H251303581074.1260.2131Yes
10CCT463801611174.0440.2333Yes
11RAP1B37101381533.8250.2510Yes
12CCNH31903472153.5630.2659Yes
13EMP141204382203.5410.2837Yes
14RAB1A23706712523.4050.2995Yes
15TBK156903382913.2580.3141Yes
16SLC25A1721003693243.1370.3284Yes
17RABGAP150503973263.1280.3443Yes
18PCNA9407543373.0900.3596Yes
19PSMA445604273513.0590.3745Yes
20PIK3C365907173862.9750.3878Yes
21DDX2161004464092.9180.4016Yes
22POLD364002784992.7150.4106Yes
23PPP2CB55705935032.7110.4243Yes
24EXOC231901325202.6770.4371Yes
25MAP3K760400686702.3610.4411Yes
26UBE2D24590671 65104467612.2290.4477Yes
27PPP2R5E70671 21200567762.2020.4581Yes
28EIF4B5390563 52705778442.1160.4653Yes
29ZDHHC516907118762.0800.4743Yes
30RABGGTB31200378852.0670.4844Yes
31ATP2A21090075 39902799391.9870.4917Yes
32FNTA7005910751.8080.4936Yes
33MAPK14529073111401.7360.4990Yes
34MCTS1613013311481.7320.5075Yes
35TOP2A36071711651.7030.5153Yes
36PSMD1273004411781.6900.5233Yes
37SIRT1119073111901.6760.5313Yes
38UBE2D3319045212521.6090.5362Yes
39TXNRD1659044613451.5080.5389Yes
40RBM1787059214251.4170.5419Yes
41GNL2662002214831.3620.5458Yes
42OGT2360131 461033315421.2980.5493Yes
43RIPK1319002515431.2970.5559Yes
44PJA243053715441.2960.5625Yes
45SUPV3L1117007216121.2290.5652Yes
46SNRPG234055116551.1800.5689Yes
47USP3206033216811.1620.5735Yes
48MRPL1536039017351.1280.5764Yes
49SIRPA130465 570033217531.1080.5811Yes
50PRIM2A700069217911.0810.5847Yes
51ELOVL6534074618251.0640.5883Yes
52CDC5L3130446 3390025 640020418521.0430.5922Yes
53RPS7686011318671.0330.5968Yes
54PPP1CC6380300 251064719430.9930.5978Yes
55MAT2A4070026 4730079 602028020510.9380.5968Yes
56TNFSF5IP1206009520660.9290.6008Yes
57GTF2B686068522630.8100.5943No
58PSMC6281002123290.7760.5947No
59MRPL35199067125740.6440.5848No
60MCM3557006826100.6270.5861No
61TCERG12350551 4540397 522074626380.6150.5878No
62XBP1384059427440.5640.5850No
63CLCN7297009527670.5550.5866No
64BCL2L11580452 4200152 542048428210.5300.5865No
65BIRC22940435 473002028840.5050.5857No
66GABPB26130450 705073530500.4440.5790No
67CCNA2529007530560.4400.5810No
68STK17B13009131980.3930.5754No
69EML4570037332020.3900.5772No
70FBXL3591014232660.3710.5757No
71MYC380541 467017033720.3370.5717No
72WEE1339007034300.3170.5702No
73USP126130735 662028034580.3090.5703No
74FNDC3A2690097 329004436350.2550.5621No
75ARFGEF2555050038040.2160.5541No
76CDC23319059339540.1860.5470No
77PSMB1294040239570.1860.5478No
78SSFA2387013347730.0910.5041No
79HSPA1L401053848370.0870.5012No
80GGPS1840128 232021549840.0770.4936No
81ACSL3314019551010.0720.4877No
82CYHR1940609 2810463 3190332 3290692 428041153490.0610.4746No
83GOPC662040053710.0600.4738No
84GDI2237006857060.0480.4559No
85CDC25C2570673 4760161 652070760030.0400.4401No
86CFLAR2320605 618044061180.0360.4341No
87VEGFC591049469220.0180.3907No
88RAB5A652032471430.0140.3788No
89SPRY2586018471680.0140.3776No
90MFAP1666009272780.0110.3717No
91SEH1L459056375460.0070.3573No
92ATG56200433 536032475860.0060.3552No
93BIRC67014876810.0040.3502No
94CRK1230162 478012876940.0040.3495No
95EPS15420021577700.0030.3455No
96TIAM236019577770.0030.3452No
97XRCC5710028678920.0010.3390No
98EPS870502048779-0.0140.2910No
99LYN60406008816-0.0150.2892No
100JAG134403908849-0.0150.2875No
101CTGF45405779137-0.0200.2721No
102NCOA61780333 64501109545-0.0270.2501No
103MTIF222602709575-0.0280.2487No
104SMARCA566200509663-0.0300.2441No
105CPT1A635009310027-0.0380.2247No
106FOSL143002110317-0.0430.2092No
107GTF2H12570746 265014810462-0.0470.2016No
108FZD1314021510538-0.0480.1978No
109FBXL7662071110661-0.0510.1915No
110CDH111230133 2100180 461011010844-0.0550.1819No
111IPO7219074610918-0.0570.1782No
112CDK7264045111047-0.0600.1716No
113IL1RL13990224 602034711246-0.0650.1612No
114MRPL1430626 3130129 522015211258-0.0660.1609No
115PRKD35220520 589051911261-0.0660.1612No
116TDG2900358 294007911399-0.0710.1541No
117CXXC584001011461-0.0730.1512No
118RBM27405060311557-0.0760.1464No
119ACTL6A5220543 6290541 2450093 4590332 527072211564-0.0760.1465No
120THRAP3618030911738-0.0820.1375No
121NUFIP1635024112178-0.1000.1142No
122B4GALT5123069212700-0.1290.0867No
123RCC1248035812929-0.1460.0750No
124CRSP6294035812979-0.1500.0732No
125HS3ST3B138004013244-0.1690.0597No
126CORO1C457039713442-0.1860.0500No
127PLAG11450142 3870139 652003913519-0.1940.0469No
128BUB1539027013543-0.1970.0466No
129HSPE1317043813651-0.2100.0419No
130PDGFB3060440 637000813712-0.2170.0397No
131RNF1450402 1340041 637068714329-0.3020.0079No
132BLZF163008814439-0.3210.0036No
133SNIP1536009214451-0.3230.0047No
134GCNT1940129 1780215 237025314515-0.3340.0030No
135PAPPA423046314662-0.361-0.0031No
136JMJD2B6350372 640047114776-0.387-0.0072No
137FADD2360593 4210692 652001914796-0.392-0.0063No
138ANLN1780113 2470537 684004714839-0.399-0.0065No
139ERCC3690000815060-0.456-0.0161No
140EIF3S101190079 384017615098-0.465-0.0157No
141MTMR4454052415156-0.484-0.0163No
142CHST2318068215161-0.485-0.0141No
143FAS4480112 611004015168-0.488-0.0119No
144DLG545021515406-0.570-0.0218No
145PSMA5539053715477-0.596-0.0226No
146TOP1770471 4060632 665032415975-0.831-0.0453No
147SFRS9380004716089-0.890-0.0468No
148ADSL557048416114-0.908-0.0435No
149DNAJA22630253 686035816201-0.960-0.0432No
150KIAA0859510497 770722 1340687 684071116202-0.963-0.0383No
151TARDBP870390 235009316405-1.070-0.0438No
152ARHGEF2336057716715-1.274-0.0540No
153SON3120148 5860239 704040316751-1.303-0.0493No
154PANX1655063216858-1.406-0.0478No
155SLC2A1210060916940-1.465-0.0447No
156BAG2290032417077-1.540-0.0442No
157FKBP1A245036817092-1.554-0.0371No
158ARFGAP14780364 539035817246-1.676-0.0368No
159RBM145340731 569031517264-1.692-0.0290No
160ZDHHC16423039017297-1.722-0.0220No
161UBE2C613001717457-1.873-0.0210No
162LHFPL245002017492-1.894-0.0132No
163HSPA82120315 1050132 655074617686-2.090-0.0130No
164BUB3317054617989-2.521-0.0164No
165MID1IP1257073918117-2.723-0.0094No
166GIPC14590348 5570438 590070718121-2.7260.0044No
167WNT5B508016218545-4.3850.0038No
Table: GSEA details [plain text format]



Fig 2: ET743_SARCOMA_72HRS_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: ET743_SARCOMA_72HRS_DN: Random ES distribution   
Gene set null distribution of ES for ET743_SARCOMA_72HRS_DN