DatasetSet_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls
#absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls
#absentNotch_versus_truncNotch_repos
Phenotypephenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos
Upregulated in classabsentNotch
GeneSetET743_SARCOMA_48HRS_DN
Enrichment Score (ES)0.6086229
Normalized Enrichment Score (NES)1.8051285
Nominal p-value0.0
FDR q-value0.009750509
FWER p-Value0.085
Table: GSEA Results Summary



Fig 1: Enrichment plot: ET743_SARCOMA_48HRS_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1LBR454067126.6560.0390Yes
2PRKACB421017096.0620.0743Yes
3HDAC24050433205.3590.1053Yes
4SLC4A1AP3190576504.7540.1317Yes
5RPP147040014664.4850.1572Yes
6TMPO4050494744.4480.1830Yes
7DDX203290348794.3580.2084Yes
8HSPH11690017844.2920.2334Yes
9GTF2H251303581074.1260.2565Yes
10CCT463801611174.0440.2798Yes
11RAP1B37101381533.8250.3004Yes
12CCNH31903472153.5630.3180Yes
13RAB1A23706712523.4050.3361Yes
14TBK156903382913.2580.3532Yes
15PSMD1456905933173.1660.3704Yes
16SLC25A1721003693243.1370.3886Yes
17PCNA9407543373.0900.4061Yes
18PSMA445604273513.0590.4233Yes
19DDX2161004464092.9180.4374Yes
20POLD364002784992.7150.4486Yes
21MAP3K760400686702.3610.4532Yes
22OSBPL925703737032.3160.4651Yes
23UBE2D24590671 65104467612.2290.4751Yes
24ZDHHC516907118762.0800.4812Yes
25RABGGTB31200378852.0670.4929Yes
26FNTA7005910751.8080.4933Yes
27MAPK14529073111401.7360.5001Yes
28MCTS1613013311481.7320.5099Yes
29TOP2A36071711651.7030.5190Yes
30SIRT1119073111901.6760.5276Yes
31UBE2D3319045212521.6090.5337Yes
32TXNRD1659044613451.5080.5376Yes
33CRLF3662001914141.4300.5423Yes
34RBM1787059214251.4170.5501Yes
35OGT2360131 461033315421.2980.5515Yes
36RIPK1319002515431.2970.5591Yes
37PJA243053715441.2960.5667Yes
38SUPV3L1117007216121.2290.5703Yes
39USP3206033216811.1620.5735Yes
40PSME3281053716871.1580.5800Yes
41MRPL1536039017351.1280.5841Yes
42SIRPA130465 570033217531.1080.5897Yes
43PRIM2A700069217911.0810.5940Yes
44ELOVL6534074618251.0640.5985Yes
45CDC5L3130446 3390025 640020418521.0430.6032Yes
46PPP1CC6380300 251064719430.9930.6042Yes
47MAT2A4070026 4730079 602028020510.9380.6039Yes
48TNFSF5IP1206009520660.9290.6086Yes
49GTF2B686068522630.8100.6028No
50PSMC6281002123290.7760.6038No
51MCM3557006826100.6270.5924No
52TCERG12350551 4540397 522074626380.6150.5945No
53XBP1384059427440.5640.5921No
54CLCN7297009527670.5550.5942No
55BCL2L11580452 4200152 542048428210.5300.5945No
56BIRC22940435 473002028840.5050.5941No
57GABPB26130450 705073530500.4440.5878No
58CCNA2529007530560.4400.5901No
59STK17B13009131980.3930.5847No
60EML4570037332020.3900.5869No
61FBXL3591014232660.3710.5856No
62USP126130735 662028034580.3090.5771No
63FNDC3A2690097 329004436350.2550.5691No
64CDC23319059339540.1860.5530No
65PSMB1294040239570.1860.5540No
66PAFAH23140451 5720593 651001442480.1410.5391No
67SSFA2387013347730.0910.5113No
68HSPA1L401053848370.0870.5084No
69RCOR1536071749100.0820.5050No
70CYHR1940609 2810463 3190332 3290692 428041153490.0610.4816No
71GOPC662040053710.0600.4808No
72CDC42BPA84067156610.0500.4655No
73CSNK2A1158057758070.0450.4579No
74CFLAR2320605 618044061180.0360.4413No
75VEGFC591049469220.0180.3980No
76RAB5A652032471430.0140.3861No
77MFAP1666009272780.0110.3790No
78ATG56200433 536032475860.0060.3624No
79BIRC67014876810.0040.3573No
80TIAM236019577770.0030.3522No
81KIF1153901397948-0.0000.3430No
82EPS870502048779-0.0140.2981No
83CTGF45405779137-0.0200.2789No
84NCOA61780333 64501109545-0.0270.2571No
85MTIF222602709575-0.0280.2557No
86ATF14570142 55500959619-0.0290.2535No
87SMARCA566200509663-0.0300.2513No
88MAPKAPK525106019831-0.0330.2425No
89FOSL143002110317-0.0430.2165No
90GTF2H12570746 265014810462-0.0470.2090No
91FZD1314021510538-0.0480.2052No
92FBXL7662071110661-0.0510.1989No
93CDH111230133 2100180 461011010844-0.0550.1894No
94IPO7219074610918-0.0570.1858No
95TRIP463007211036-0.0600.1798No
96CDK7264045111047-0.0600.1796No
97MRPL1430626 3130129 522015211258-0.0660.1686No
98TDG2900358 294007911399-0.0710.1615No
99CXXC584001011461-0.0730.1586No
100RBM27405060311557-0.0760.1539No
101JMJD1C940575 212002511594-0.0770.1524No
102NMI52027011645-0.0790.1501No
103THRAP3618030911738-0.0820.1456No
104NBN730538 2470619 478059412073-0.0950.1281No
105NUFIP1635024112178-0.1000.1231No
106B4GALT5123069212700-0.1290.0956No
107PLK11780369 264012112890-0.1430.0863No
108CRSP6294035812979-0.1500.0824No
109HS3ST3B138004013244-0.1690.0691No
110PLAG11450142 3870139 652003913519-0.1940.0554No
111BUB1539027013543-0.1970.0553No
112HSPE1317043813651-0.2100.0507No
113PDGFB3060440 637000813712-0.2170.0488No
114RNF1450402 1340041 637068714329-0.3020.0172No
115BLZF163008814439-0.3210.0132No
116SNIP1536009214451-0.3230.0145No
117UBN1590019515041-0.451-0.0147No
118ERCC3690000815060-0.456-0.0130No
119EIF3S101190079 384017615098-0.465-0.0123No
120MTMR4454052415156-0.484-0.0125No
121DLG545021515406-0.570-0.0227No
122PSMA5539053715477-0.596-0.0229No
123PSMC2704001015750-0.707-0.0335No
124TOP1770471 4060632 665032415975-0.831-0.0407No
125SFRS9380004716089-0.890-0.0416No
126ADSL557048416114-0.908-0.0376No
127DNAJA22630253 686035816201-0.960-0.0366No
128KIAA0859510497 770722 1340687 684071116202-0.963-0.0309No
129TARDBP870390 235009316405-1.070-0.0356No
130SON3120148 5860239 704040316751-1.303-0.0466No
131PANX1655063216858-1.406-0.0441No
132SLC2A1210060916940-1.465-0.0398No
133BAG2290032417077-1.540-0.0381No
134ARFGAP14780364 539035817246-1.676-0.0374No
135RBM145340731 569031517264-1.692-0.0284No
136ZDHHC16423039017297-1.722-0.0200No
137UBE2C613001717457-1.873-0.0176No
138LHFPL245002017492-1.894-0.0083No
139HSPA82120315 1050132 655074617686-2.090-0.0064No
140BUB3317054617989-2.521-0.0080No
141MID1IP1257073918117-2.7230.0012No
142WNT5B508016218545-4.3850.0038No
Table: GSEA details [plain text format]



Fig 2: ET743_SARCOMA_48HRS_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: ET743_SARCOMA_48HRS_DN: Random ES distribution   
Gene set null distribution of ES for ET743_SARCOMA_48HRS_DN