Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_02_ATM_minus_versus_BT_ATM_minus.phenotype_ATM_minus_versus_BT_ATM_minus.cls #ATM_minus_versus_BT_ATM_minus.phenotype_ATM_minus_versus_BT_ATM_minus.cls #ATM_minus_versus_BT_ATM_minus_repos |
| Phenotype | phenotype_ATM_minus_versus_BT_ATM_minus.cls#ATM_minus_versus_BT_ATM_minus_repos |
| Upregulated in class | BT_ATM_minus |
| GeneSet | MAPK_CASCADE |
| Enrichment Score (ES) | -0.59247214 |
| Normalized Enrichment Score (NES) | -1.8040172 |
| Nominal p-value | 0.0020 |
| FDR q-value | 0.10671738 |
| FWER p-Value | 0.837 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | KRAS | 1426228_at 1426229_s_at 1434000_at 1451979_at | 314 | 4.481 | 0.0525 | No | ||
| 2 | MAP3K12 | 1417115_at 1438908_at 1456565_s_at | 732 | 3.365 | 0.0837 | No | ||
| 3 | TIMP1 | 1460227_at | 1529 | 2.465 | 0.0842 | No | ||
| 4 | MAPK10 | 1437195_x_at 1448342_at 1458002_at 1458062_at 1458513_at | 1671 | 2.356 | 0.1129 | No | ||
| 5 | PLCB3 | 1448661_at | 6320 | 0.920 | -0.0856 | No | ||
| 6 | MAP2K1 | 1416351_at | 6572 | 0.873 | -0.0840 | No | ||
| 7 | MAP2K2 | 1415974_at 1443436_at 1460636_at | 7957 | 0.639 | -0.1377 | No | ||
| 8 | MAPK12 | 1447823_x_at 1449283_a_at | 7998 | 0.632 | -0.1301 | No | ||
| 9 | RRAS | 1418448_at | 9028 | 0.470 | -0.1700 | No | ||
| 10 | MAPK14 | 1416703_at 1416704_at 1426104_at 1442364_at 1451927_a_at 1459617_at | 9589 | 0.387 | -0.1898 | No | ||
| 11 | MBP | 1419646_a_at 1425263_a_at 1425264_s_at 1433532_a_at 1436201_x_at 1451961_a_at 1454651_x_at 1456228_x_at | 12253 | -0.024 | -0.3110 | No | ||
| 12 | HRAS | 1422407_s_at 1424132_at | 12431 | -0.057 | -0.3182 | No | ||
| 13 | NRAS | 1422688_a_at 1454060_a_at | 13011 | -0.158 | -0.3423 | No | ||
| 14 | BRAF | 1425693_at 1435434_at 1435480_at 1442749_at 1445786_at 1447940_a_at 1447941_x_at 1456505_at 1458641_at | 13338 | -0.213 | -0.3540 | No | ||
| 15 | MAP2K3 | 1425456_a_at 1451714_a_at | 15187 | -0.559 | -0.4300 | No | ||
| 16 | MAP3K2 | 1422250_at | 17161 | -1.011 | -0.5050 | No | ||
| 17 | JUN | 1417409_at 1448694_at | 18344 | -1.347 | -0.5389 | No | ||
| 18 | ELK1 | 1421896_at 1421897_at 1446390_at | 18520 | -1.412 | -0.5258 | No | ||
| 19 | MAPK1 | 1419568_at 1426585_s_at 1442876_at 1453104_at | 19751 | -2.036 | -0.5516 | Yes | ||
| 20 | MAP3K1 | 1424850_at | 20648 | -2.888 | -0.5494 | Yes | ||
| 21 | ARAF | 1426602_at 1428607_at 1435566_s_at 1440764_at 1445693_at | 20683 | -2.932 | -0.5072 | Yes | ||
| 22 | RASA3 | 1415850_at | 20725 | -2.996 | -0.4643 | Yes | ||
| 23 | MAPK3 | 1427060_at | 20984 | -3.442 | -0.4248 | Yes | ||
| 24 | MAP3K3 | 1426686_s_at 1426687_at 1436522_at | 21072 | -3.604 | -0.3749 | Yes | ||
| 25 | SIPA1 | 1416206_at | 21252 | -3.966 | -0.3239 | Yes | ||
| 26 | MAP2K4 | 1426233_at 1442679_at 1451982_at | 21293 | -4.054 | -0.2653 | Yes | ||
| 27 | RAF1 | 1416078_s_at 1425419_a_at | 21451 | -4.510 | -0.2051 | Yes | ||
| 28 | MAP2K6 | 1426850_a_at 1459292_at | 21619 | -5.264 | -0.1342 | Yes | ||
| 29 | MAP2K7 | 1421416_at 1425393_a_at 1425512_at 1425513_at 1440442_at 1451736_a_at 1457182_at | 21902 | -9.953 | 0.0015 | Yes |
