Details for gene set ENZYME

Table: GSEA Results Summary

Dataset	Set_02_ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus_repos
Phenotype	phenotype_ATM_minus_versus_ATM_plus.cls#ATM_minus_versus_ATM_plus_repos
Upregulated in class	ATM_plus
GeneSet	ENZYME_BINDING
Enrichment Score (ES)	-0.43591222
Normalized Enrichment Score (NES)	-1.7012075
Nominal p-value	0.0
FDR q-value	0.2349818
FWER p-Value	0.987

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	UBE2L3	1417907_at 1417908_s_at 1448879_at 1448880_at	538	3.891	-0.0104	No
2	RANBP1	1422547_at	570	3.814	0.0022	No
3	PRDX3	1416292_at	711	3.539	0.0087	No
4	LCK	1425396_a_at 1439145_at 1439146_s_at 1457917_at	819	3.338	0.0161	No
5	HINT1	1424017_a_at 1424018_at 1457286_at	1152	2.878	0.0114	No
6	RANBP5	1426945_at 1426946_at 1431706_at	1274	2.745	0.0159	No
7	AKAP3	1421531_at 1456591_x_at	1390	2.640	0.0204	No
8	CDKN2A	1450140_a_at	1423	2.597	0.0284	No
9	ADAM9	1416094_at	1440	2.578	0.0372	No
10	CUTA	1451387_s_at	1601	2.429	0.0387	No
11	YWHAG	1420816_at 1420817_at 1450012_x_at 1459693_x_at	2016	2.146	0.0276	No
12	MAGI2	1420532_at 1440807_at 1454855_at	2295	2.003	0.0222	No
13	UBQLN1	1419385_a_at 1424368_s_at 1450345_at	2510	1.898	0.0194	No
14	RASA1	1426476_at 1426477_at 1426478_at 1438998_at	3122	1.674	-0.0026	No
15	MAP3K12	1417115_at 1438908_at 1456565_s_at	3462	1.574	-0.0123	No
16	LATS1	1427679_at 1460264_at	3580	1.533	-0.0121	No
17	DOCK4	1431114_at 1436405_at 1441462_at 1441469_at 1446283_at 1457146_at 1459279_at	3722	1.496	-0.0131	No
18	IRS1	1423104_at	3910	1.444	-0.0164	No
19	ATG3	1418179_at 1448993_at	3954	1.431	-0.0131	No
20	DMXL2	1428749_at	4092	1.395	-0.0142	No
21	PAWR	1444808_at 1445390_at	4146	1.382	-0.0116	No
22	TOP2A	1427724_at 1442454_at 1454694_a_at	4229	1.366	-0.0103	No
23	ADAMTSL4	1451932_a_at	4339	1.342	-0.0104	No
24	RILP	1457696_at	4440	1.315	-0.0102	No
25	CSF3	1419427_at	4491	1.302	-0.0077	No
26	SERPINE1	1419149_at	4700	1.255	-0.0126	No
27	TPRKB	1424992_at 1425410_at 1425682_a_at	4776	1.243	-0.0115	No
28	PPP2R4	1439383_x_at 1439393_x_at 1448138_at	5402	1.126	-0.0361	No
29	FAF1	1418242_at 1434370_s_at	5501	1.107	-0.0365	No
30	APOC2	1418069_at	5555	1.096	-0.0349	No
31	CD24	1416034_at 1437502_x_at 1448182_a_at	5614	1.087	-0.0336	No
32	NOS1AP	1430442_at 1437485_at	5809	1.055	-0.0386	No
33	TOPORS	1417754_at 1417755_at 1448838_at	5867	1.046	-0.0374	No
34	GOLGA5	1418447_at	5981	1.029	-0.0388	No
35	ZC3HC1	1426654_at	6089	1.011	-0.0400	No
36	SOD1	1435304_at 1440222_at 1440896_at 1451124_at 1459976_s_at	6699	0.919	-0.0646	No
37	MAPK8IP3	1416437_a_at 1425975_a_at 1436676_at 1460628_at	6716	0.917	-0.0620	No
38	AVPR1B	1422204_at	6921	0.889	-0.0681	No
39	GRK5	1446361_at 1446998_at 1449514_at	7153	0.851	-0.0756	No
40	AKAP7	1422143_at 1433905_at	7277	0.829	-0.0782	No
41	MOBKL1A	1430564_at 1455184_at	7313	0.824	-0.0767	No
42	TP53	1426538_a_at 1427739_a_at 1438808_at 1457623_x_at 1459780_at 1459781_x_at	7499	0.796	-0.0823	No
43	ZP3	1419007_at	7550	0.788	-0.0817	No
44	AKAP11	1434764_at	7847	0.747	-0.0926	No
45	MAP3K13	1430137_at 1440749_at 1447699_at	7858	0.745	-0.0903	No
46	DLG1	1415691_at 1445798_at 1450768_at 1459635_at	8048	0.719	-0.0963	No
47	AKAP5	1447301_at	8158	0.700	-0.0988	No
48	TRIB3	1426065_a_at 1456225_x_at	8244	0.686	-0.1002	No
49	APOA5	1417610_at	8335	0.673	-0.1018	No
50	AKAP12	1419706_a_at 1458235_at	8394	0.664	-0.1020	No
51	GCLM	1418627_at	8519	0.644	-0.1054	No
52	PTPRC	1422124_a_at 1440165_at	8547	0.641	-0.1043	No
53	IGF1R	1426565_at 1437219_at 1443566_at 1445600_at 1445664_at 1446303_at	8553	0.639	-0.1021	No
54	ARHGEF2	1421042_at 1421043_s_at 1427646_a_at	8589	0.635	-0.1014	No
55	IRAK1	1448668_a_at 1460649_at	8837	0.599	-0.1106	No
56	HDAC2	1439704_at 1445684_s_at 1449080_at	9093	0.563	-0.1202	No
57	AVPR1A	1418603_at 1418604_at	9356	0.525	-0.1303	No
58	DNMT3L	1425035_s_at	9389	0.521	-0.1299	No
59	CDKN2C	1416868_at 1439164_at	9503	0.503	-0.1332	No
60	HIF1A	1427418_a_at 1431981_at 1448183_a_at 1457231_at	9804	0.461	-0.1453	No
61	VAPB	1423152_at 1436079_s_at 1445370_at 1458501_at	10066	0.426	-0.1557	No
62	FGD5	1460578_at	10122	0.421	-0.1567	No
63	MAPK8IP2	1418785_at 1418786_at 1435045_s_at 1449225_a_at 1455194_at	10178	0.414	-0.1577	No
64	NFKBIA	1420088_at 1420089_at 1438157_s_at 1448306_at 1449731_s_at	10443	0.375	-0.1684	No
65	VWF	1435386_at	10453	0.374	-0.1675	No
66	MAST2	1417324_at 1440321_at 1441847_at 1444813_at 1456927_at 1459558_at	10941	0.308	-0.1887	No
67	S100A1	1417421_at 1419814_s_at	10981	0.302	-0.1894	No
68	DHCR24	1418129_at 1451895_a_at	11264	0.260	-0.2014	No
69	MAPT	1417885_at 1424718_at 1424719_a_at 1445634_at 1455028_at	11333	0.250	-0.2036	No
70	RAPGEF6	1427412_s_at 1434509_at 1438828_at 1443877_a_at 1443878_at	11372	0.244	-0.2044	No
71	ALS2	1417783_at 1417784_at 1431608_at 1446183_at	11496	0.227	-0.2093	No
72	FGD4	1425037_at 1426041_a_at 1426042_at 1451659_at 1455337_at	11557	0.219	-0.2112	No
73	NPC2	1416901_at 1443266_at 1448513_a_at 1455768_at	11760	0.188	-0.2198	No
74	PPME1	1423810_at 1445792_at	11781	0.184	-0.2200	No
75	PDLIM5	1429783_at 1438186_at 1442710_at 1446339_at	11813	0.180	-0.2208	No
76	HDAC1	1448246_at	11842	0.175	-0.2214	No
77	PLCE1	1452398_at	11872	0.170	-0.2222	No
78	YWHAE	1426384_a_at 1426385_x_at 1435702_s_at 1438839_a_at 1440841_at 1457173_at	11962	0.157	-0.2257	No
79	IPO7	1442511_at 1454955_at 1458165_at	12118	0.133	-0.2323	No
80	APC	1420956_at 1420957_at 1435543_at 1450056_at	12128	0.131	-0.2322	No
81	SPDYA	1429470_at 1432134_at 1441390_at	12135	0.130	-0.2320	No
82	CDC42EP5	1418712_at 1430018_at	12437	0.087	-0.2455	No
83	ZP2	1449016_at	12528	0.073	-0.2494	No
84	PTPRR	1426047_a_at	12988	-0.000	-0.2705	No
85	AKAP4	1419019_a_at 1431868_at 1451661_at 1451662_x_at	13031	-0.008	-0.2724	No
86	FGD2	1419515_at	13370	-0.065	-0.2877	No
87	RTKN	1425601_a_at	13604	-0.103	-0.2980	No
88	CDKN2B	1449152_at	13616	-0.106	-0.2981	No
89	TREX2	1449367_at	13658	-0.115	-0.2996	No
90	CCND3	1415907_at 1437584_at 1444323_at 1446567_at 1447434_at 1457549_at	13695	-0.125	-0.3008	No
91	INSR	1421380_at 1450225_at	14062	-0.189	-0.3169	No
92	EPAS1	1435436_at 1449888_at	14367	-0.246	-0.3299	No
93	PLAUR	1452521_a_at	14509	-0.272	-0.3354	No
94	SERPINA5	1418813_at	14519	-0.274	-0.3348	No
95	ANK1	1419421_at 1425677_a_at 1443291_at 1450627_at 1452512_a_at	14725	-0.313	-0.3431	No
96	BCL10	1418970_a_at 1418971_x_at 1418972_at 1443524_x_at	14734	-0.314	-0.3423	No
97	RANBP2	1422621_at 1440104_at 1445883_at 1450690_at	14925	-0.352	-0.3497	No
98	FGD6	1419322_at 1435467_at	15298	-0.429	-0.3652	No
99	CDK5RAP2	1443976_at 1447103_at 1452618_at	15353	-0.442	-0.3661	No
100	BCL2	1422938_at 1427818_at 1437122_at 1440770_at 1443837_x_at 1457687_at	15444	-0.468	-0.3685	No
101	GCN5L2	1422971_at 1422972_s_at 1426783_at	15474	-0.473	-0.3681	No
102	RB1	1417850_at 1441494_at 1444400_at 1444454_at 1457447_at	15532	-0.490	-0.3689	No
103	PARD6A	1449100_at	15627	-0.516	-0.3713	No
104	ZBTB7A	1437255_at 1450093_s_at 1452932_at	15748	-0.546	-0.3749	No
105	SMG5	1434546_at 1451797_at	16276	-0.682	-0.3966	No
106	BCAR1	1439388_s_at 1450622_at	16323	-0.693	-0.3961	No
107	ABCA1	1421839_at 1421840_at 1450392_at	16331	-0.695	-0.3939	No
108	ADAM10	1450104_at 1460083_at	16460	-0.735	-0.3971	No
109	HDAC10	1441832_at 1454775_at	16661	-0.800	-0.4033	No
110	GGA2	1428141_at 1457955_at	16731	-0.818	-0.4035	No
111	MDM2	1423605_a_at 1427718_a_at 1457929_at	16738	-0.819	-0.4007	No
112	PIK3R1	1425514_at 1425515_at 1438682_at 1444591_at 1451737_at	16790	-0.838	-0.4000	No
113	PRKCD	1422847_a_at 1442256_at	16936	-0.882	-0.4034	No
114	CD40	1439221_s_at 1449473_s_at 1460415_a_at	16998	-0.899	-0.4029	No
115	ABAT	1433855_at	17070	-0.925	-0.4028	No
116	MAPK8IP1	1425679_a_at 1440619_at	17141	-0.947	-0.4025	No
117	RANBP9	1422736_at 1448064_at 1456199_x_at	17414	-1.034	-0.4112	No
118	SMG7	1440107_at 1455574_at 1456933_at	17660	-1.129	-0.4183	No
119	FGD3	1433398_at 1450235_at 1454593_at	17686	-1.149	-0.4153	No
120	IPO9	1424466_at 1439481_at 1441645_s_at	18011	-1.279	-0.4254	No
121	BRCA1	1424629_at 1424630_a_at 1427698_at 1443763_at 1451417_at	18057	-1.299	-0.4227	No
122	CYFIP1	1416329_at 1445327_at 1457134_at 1457615_at	18345	-1.438	-0.4306	Yes
123	IPO8	1426760_at 1452185_at 1459203_at	18455	-1.490	-0.4302	Yes
124	SQSTM1	1440076_at 1442237_at 1444021_at 1450957_a_at	18467	-1.501	-0.4252	Yes
125	CDC42EP2	1428750_at 1445870_at	18617	-1.558	-0.4263	Yes
126	KIF13B	1433158_at 1433159_at 1436056_at 1453276_at	18726	-1.616	-0.4253	Yes
127	FGD1	1416865_at 1437369_at 1459278_at	18733	-1.620	-0.4196	Yes
128	IL6R	1422270_a_at 1452416_at	18765	-1.651	-0.4150	Yes
129	COTL1	1416001_a_at 1416002_x_at 1425801_x_at 1436236_x_at 1436838_x_at 1437811_x_at	18769	-1.652	-0.4090	Yes
130	PACSIN3	1416995_at 1431534_at 1437834_s_at 1456191_x_at	18823	-1.681	-0.4053	Yes
131	TOP2B	1416731_at 1416732_at 1448458_at 1456688_at	18886	-1.709	-0.4019	Yes
132	FIZ1	1423733_a_at	19118	-1.881	-0.4056	Yes
133	SIRT2	1423507_a_at	19236	-1.972	-0.4037	Yes
134	PICK1	1419384_at	19351	-2.042	-0.4014	Yes
135	CASP2	1448165_at	19399	-2.069	-0.3960	Yes
136	RALBP1	1417248_at 1448634_at	19552	-2.164	-0.3950	Yes
137	RPS6KA4	1438243_at 1448498_at	19778	-2.357	-0.3967	Yes
138	DFFB	1421229_at 1437051_at	19782	-2.361	-0.3882	Yes
139	SAPS3	1423881_at 1429939_at 1439161_at 1447118_at 1454030_at	19965	-2.544	-0.3872	Yes
140	PCAF	1434037_s_at 1444473_at 1445105_at 1450821_at	20155	-2.754	-0.3857	Yes
141	AKAP8L	1417734_at	20216	-2.820	-0.3781	Yes
142	RAB3GAP1	1455922_at	20299	-2.905	-0.3712	Yes
143	UBE4B	1432499_a_at 1444465_at 1448410_at	20359	-2.986	-0.3630	Yes
144	BCOR	1428773_s_at 1429438_at 1452910_at	20455	-3.096	-0.3560	Yes
145	TRIP6	1449041_a_at	20609	-3.320	-0.3508	Yes
146	SUPT5H	1424255_at	20860	-3.701	-0.3487	Yes
147	RAD9A	1418404_at	20884	-3.736	-0.3360	Yes
148	RELA	1419536_a_at	20962	-3.850	-0.3254	Yes
149	MAP2K7	1421416_at 1425393_a_at 1425512_at 1425513_at 1440442_at 1451736_a_at 1457182_at	20978	-3.880	-0.3118	Yes
150	CAMK2N1	1456609_at	21034	-3.975	-0.2998	Yes
151	LLGL1	1416621_at	21306	-4.663	-0.2951	Yes
152	PARP4	1441026_at	21345	-4.779	-0.2793	Yes
153	ARFIP2	1424240_at 1435498_at	21356	-4.802	-0.2621	Yes
154	CD4	1419696_at 1427779_a_at	21401	-4.963	-0.2459	Yes
155	SOCS1	1440047_at 1450446_a_at	21486	-5.335	-0.2301	Yes
156	CEP250	1421512_at	21615	-6.003	-0.2139	Yes
157	LAX1	1438687_at	21659	-6.247	-0.1930	Yes
158	ITGB2	1450678_at	21698	-6.716	-0.1700	Yes
159	GGA3	1438008_at	21712	-6.831	-0.1455	Yes
160	SIT1	1418751_at	21835	-8.815	-0.1188	Yes
161	CDKN2D	1416253_at	21862	-9.545	-0.0849	Yes
162	RANBP3	1452673_at 1457711_at 1460612_at	21916	-11.973	-0.0433	Yes
163	ATPIF1	1434198_at 1448770_a_at 1453681_at	21917	-12.006	0.0008	Yes