Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_02_ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus_repos |
| Phenotype | phenotype_ATM_minus_versus_ATM_plus.cls#ATM_minus_versus_ATM_plus_repos |
| Upregulated in class | ATM_plus |
| GeneSet | KERATINOCYTEPATHWAY |
| Enrichment Score (ES) | -0.6313861 |
| Normalized Enrichment Score (NES) | -1.9949019 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.011101271 |
| FWER p-Value | 0.075 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CHUK | 1417091_at 1428210_s_at 1451383_a_at | 1214 | 2.804 | -0.0242 | No | ||
| 2 | CEBPA | 1418982_at | 2939 | 1.737 | -0.0836 | No | ||
| 3 | IKBKB | 1426207_at 1426333_a_at 1432275_at 1445141_at 1454184_a_at | 3962 | 1.430 | -0.1143 | No | ||
| 4 | PRKCH | 1422079_at 1434248_at | 5573 | 1.094 | -0.1757 | No | ||
| 5 | MAPK13 | 1448871_at | 5959 | 1.032 | -0.1817 | No | ||
| 6 | HRAS | 1422407_s_at 1424132_at | 7380 | 0.815 | -0.2375 | No | ||
| 7 | EGFR | 1424932_at 1432647_at 1435888_at 1451530_at 1454313_at 1457563_at 1460420_a_at | 7824 | 0.750 | -0.2494 | No | ||
| 8 | PRKCB1 | 1423478_at 1438981_at 1443144_at 1459674_at 1460419_a_at | 8413 | 0.661 | -0.2689 | No | ||
| 9 | HOXA7 | 1449499_at | 9021 | 0.573 | -0.2902 | No | ||
| 10 | TNF | 1419607_at | 9533 | 0.499 | -0.3080 | No | ||
| 11 | EGF | 1418093_a_at | 10299 | 0.397 | -0.3385 | No | ||
| 12 | NFKBIA | 1420088_at 1420089_at 1438157_s_at 1448306_at 1449731_s_at | 10443 | 0.375 | -0.3409 | No | ||
| 13 | PRKCA | 1427562_a_at 1443069_at 1445028_at 1445395_at 1446598_at 1450945_at | 11573 | 0.217 | -0.3900 | No | ||
| 14 | NFKB1 | 1427705_a_at 1442949_at | 11848 | 0.175 | -0.4006 | No | ||
| 15 | MAP2K3 | 1425456_a_at 1451714_a_at | 12419 | 0.089 | -0.4256 | No | ||
| 16 | MAPK14 | 1416703_at 1416704_at 1426104_at 1442364_at 1451927_a_at 1459617_at | 13846 | -0.151 | -0.4891 | No | ||
| 17 | BCL2 | 1422938_at 1427818_at 1437122_at 1440770_at 1443837_x_at 1457687_at | 15444 | -0.468 | -0.5568 | No | ||
| 18 | MAP2K1 | 1416351_at | 16403 | -0.715 | -0.5926 | No | ||
| 19 | MAPK8 | 1420931_at 1420932_at 1437045_at 1440856_at 1457936_at | 16570 | -0.764 | -0.5917 | No | ||
| 20 | JUN | 1417409_at 1448694_at | 16926 | -0.879 | -0.5981 | No | ||
| 21 | PRKCD | 1422847_a_at 1442256_at | 16936 | -0.882 | -0.5886 | No | ||
| 22 | RIPK1 | 1419508_at 1439273_at 1449485_at | 17018 | -0.908 | -0.5822 | No | ||
| 23 | DAXX | 1419026_at | 17755 | -1.177 | -0.6027 | No | ||
| 24 | PPP2CA | 1417367_at 1444875_at 1456390_at | 17832 | -1.205 | -0.5928 | No | ||
| 25 | PRKCE | 1437860_at 1437861_s_at 1442609_at 1444649_at 1449956_at 1452878_at | 17869 | -1.223 | -0.5808 | No | ||
| 26 | MAPK1 | 1419568_at 1426585_s_at 1442876_at 1453104_at | 18978 | -1.781 | -0.6115 | Yes | ||
| 27 | TNFRSF1B | 1418099_at 1448951_at | 19320 | -2.022 | -0.6046 | Yes | ||
| 28 | ETS2 | 1416268_at 1437809_x_at 1447685_x_at | 19651 | -2.244 | -0.5946 | Yes | ||
| 29 | MAP3K14 | 1422999_at 1434364_at | 20053 | -2.632 | -0.5836 | Yes | ||
| 30 | MAP2K4 | 1426233_at 1442679_at 1451982_at | 20425 | -3.061 | -0.5664 | Yes | ||
| 31 | MAPK3 | 1427060_at | 20670 | -3.407 | -0.5396 | Yes | ||
| 32 | PRKCQ | 1426044_a_at | 20749 | -3.522 | -0.5039 | Yes | ||
| 33 | MAP2K6 | 1426850_a_at 1459292_at | 20947 | -3.821 | -0.4703 | Yes | ||
| 34 | RELA | 1419536_a_at | 20962 | -3.850 | -0.4280 | Yes | ||
| 35 | SP1 | 1418180_at 1448994_at 1454852_at | 20975 | -3.869 | -0.3854 | Yes | ||
| 36 | MAP2K7 | 1421416_at 1425393_a_at 1425512_at 1425513_at 1440442_at 1451736_a_at 1457182_at | 20978 | -3.880 | -0.3423 | Yes | ||
| 37 | TRAF2 | 1451233_at | 21088 | -4.116 | -0.3014 | Yes | ||
| 38 | FOS | 1423100_at | 21153 | -4.275 | -0.2566 | Yes | ||
| 39 | RAF1 | 1416078_s_at 1425419_a_at | 21295 | -4.634 | -0.2114 | Yes | ||
| 40 | MAP3K1 | 1424850_at | 21629 | -6.080 | -0.1588 | Yes | ||
| 41 | ETS1 | 1422027_a_at 1422028_a_at 1426725_s_at 1452163_at | 21663 | -6.261 | -0.0905 | Yes | ||
| 42 | TNFRSF1A | 1417291_at | 21853 | -9.228 | 0.0037 | Yes |
