Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_02_ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus_repos |
| Phenotype | phenotype_ATM_minus_versus_ATM_plus.cls#ATM_minus_versus_ATM_plus_repos |
| Upregulated in class | ATM_plus |
| GeneSet | HIVNEFPATHWAY |
| Enrichment Score (ES) | -0.6225619 |
| Normalized Enrichment Score (NES) | -2.057422 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0052853264 |
| FWER p-Value | 0.021 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CYCS | 1422484_at 1445484_at | 57 | 6.950 | 0.0477 | No | ||
| 2 | CHUK | 1417091_at 1428210_s_at 1451383_a_at | 1214 | 2.804 | 0.0152 | No | ||
| 3 | LMNB2 | 1451849_a_at | 1755 | 2.315 | 0.0073 | No | ||
| 4 | RASA1 | 1426476_at 1426477_at 1426478_at 1438998_at | 3122 | 1.674 | -0.0430 | No | ||
| 5 | CASP8 | 1424552_at | 3709 | 1.500 | -0.0589 | No | ||
| 6 | LMNB1 | 1423520_at 1423521_at | 4277 | 1.358 | -0.0749 | No | ||
| 7 | PSEN2 | 1425869_a_at 1431542_at | 5571 | 1.094 | -0.1261 | No | ||
| 8 | TNF | 1419607_at | 9533 | 0.499 | -0.3035 | No | ||
| 9 | GSN | 1415812_at 1436991_x_at 1437171_x_at 1441225_at 1456312_x_at 1456568_at 1456569_x_at | 10036 | 0.430 | -0.3233 | No | ||
| 10 | NFKBIA | 1420088_at 1420089_at 1438157_s_at 1448306_at 1449731_s_at | 10443 | 0.375 | -0.3391 | No | ||
| 11 | CASP3 | 1426165_a_at 1430192_at 1449839_at | 10481 | 0.370 | -0.3382 | No | ||
| 12 | CDC2L1 | 1418841_s_at | 10791 | 0.327 | -0.3499 | No | ||
| 13 | NFKB1 | 1427705_a_at 1442949_at | 11848 | 0.175 | -0.3969 | No | ||
| 14 | LMNA | 1421654_a_at 1425472_a_at 1426868_x_at 1452212_at 1457670_s_at | 12378 | 0.094 | -0.4204 | No | ||
| 15 | NUMA1 | 1423974_at 1423975_s_at 1441090_at 1444576_at 1444577_x_at | 13859 | -0.153 | -0.4869 | No | ||
| 16 | BID | 1417045_at 1447873_x_at 1448560_at | 14384 | -0.248 | -0.5091 | No | ||
| 17 | CRADD | 1427505_a_at 1443430_at | 14523 | -0.274 | -0.5134 | No | ||
| 18 | PSEN1 | 1420261_at 1421853_at 1425549_at 1450399_at | 15004 | -0.370 | -0.5326 | No | ||
| 19 | BCL2 | 1422938_at 1427818_at 1437122_at 1440770_at 1443837_x_at 1457687_at | 15444 | -0.468 | -0.5493 | No | ||
| 20 | RB1 | 1417850_at 1441494_at 1444400_at 1444454_at 1457447_at | 15532 | -0.490 | -0.5497 | No | ||
| 21 | PRKDC | 1451576_at | 15548 | -0.496 | -0.5468 | No | ||
| 22 | MAPK8 | 1420931_at 1420932_at 1437045_at 1440856_at 1457936_at | 16570 | -0.764 | -0.5880 | No | ||
| 23 | MDM2 | 1423605_a_at 1427718_a_at 1457929_at | 16738 | -0.819 | -0.5896 | No | ||
| 24 | TRADD | 1429117_at 1439910_a_at 1452622_a_at | 16801 | -0.841 | -0.5864 | No | ||
| 25 | PRKCD | 1422847_a_at 1442256_at | 16936 | -0.882 | -0.5861 | No | ||
| 26 | RIPK1 | 1419508_at 1439273_at 1449485_at | 17018 | -0.908 | -0.5832 | No | ||
| 27 | PTK2 | 1423059_at 1430827_a_at 1439198_at 1440082_at 1441475_at 1443384_at 1445137_at | 17364 | -1.019 | -0.5916 | No | ||
| 28 | BIRC3 | 1421392_a_at 1425223_at | 17639 | -1.121 | -0.5960 | No | ||
| 29 | DAXX | 1419026_at | 17755 | -1.177 | -0.5928 | No | ||
| 30 | CASP9 | 1426125_a_at 1437537_at 1457816_at | 17786 | -1.190 | -0.5855 | No | ||
| 31 | PAK2 | 1434250_at 1454887_at | 18107 | -1.315 | -0.5906 | No | ||
| 32 | BAG4 | 1418707_at 1439024_at 1449186_at | 18489 | -1.510 | -0.5971 | No | ||
| 33 | FADD | 1416888_at 1446499_at | 18889 | -1.709 | -0.6029 | No | ||
| 34 | TNFRSF1B | 1418099_at 1448951_at | 19320 | -2.022 | -0.6079 | Yes | ||
| 35 | CASP2 | 1448165_at | 19399 | -2.069 | -0.5965 | Yes | ||
| 36 | BIRC4 | 1421394_a_at 1426636_a_at 1437533_at 1440351_at 1450231_a_at 1450232_at 1456088_at | 19429 | -2.090 | -0.5827 | Yes | ||
| 37 | DFFB | 1421229_at 1437051_at | 19782 | -2.361 | -0.5816 | Yes | ||
| 38 | MAP3K14 | 1422999_at 1434364_at | 20053 | -2.632 | -0.5749 | Yes | ||
| 39 | APAF1 | 1450223_at | 20613 | -3.326 | -0.5764 | Yes | ||
| 40 | ACTG1 | 1415779_s_at | 20795 | -3.592 | -0.5586 | Yes | ||
| 41 | BIRC2 | 1418854_at | 20809 | -3.626 | -0.5329 | Yes | ||
| 42 | RELA | 1419536_a_at | 20962 | -3.850 | -0.5120 | Yes | ||
| 43 | MAP2K7 | 1421416_at 1425393_a_at 1425512_at 1425513_at 1440442_at 1451736_a_at 1457182_at | 20978 | -3.880 | -0.4846 | Yes | ||
| 44 | TRAF2 | 1451233_at | 21088 | -4.116 | -0.4597 | Yes | ||
| 45 | TRAF1 | 1423602_at 1445452_at | 21192 | -4.381 | -0.4327 | Yes | ||
| 46 | ARHGDIB | 1426454_at | 21447 | -5.166 | -0.4069 | Yes | ||
| 47 | MAP3K1 | 1424850_at | 21629 | -6.080 | -0.3711 | Yes | ||
| 48 | CFLAR | 1424996_at 1425686_at 1425687_at 1439600_at 1449317_at | 21824 | -8.576 | -0.3178 | Yes | ||
| 49 | TNFRSF1A | 1417291_at | 21853 | -9.228 | -0.2522 | Yes | ||
| 50 | CASP7 | 1426062_a_at 1448659_at | 21890 | -11.018 | -0.1741 | Yes | ||
| 51 | DFFA | 1450885_at 1457564_at | 21920 | -12.111 | -0.0876 | Yes | ||
| 52 | CASP6 | 1415995_at 1458715_at | 21923 | -12.179 | 0.0005 | Yes |
