Dataset | Set_02_ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus_repos |
Phenotype | phenotype_ATM_minus_versus_ATM_plus.cls#ATM_minus_versus_ATM_plus_repos |
Upregulated in class | ATM_plus |
GeneSet | BRENTANI_SIGNALING |
Enrichment Score (ES) | -0.48890507 |
Normalized Enrichment Score (NES) | -1.9248174 |
Nominal p-value | 0.0 |
FDR q-value | 0.014822778 |
FWER p-Value | 0.233 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | CRKL | 1421953_at 1421954_at 1425604_at 1436950_at | 324 | 4.648 | 0.0004 | No | ||
2 | AXIN1 | 1426966_at 1426967_at 1441029_at | 1066 | 2.980 | -0.0238 | No | ||
3 | MAPK10 | 1437195_x_at 1448342_at 1458002_at 1458062_at 1458513_at | 1309 | 2.715 | -0.0260 | No | ||
4 | TNFRSF10B | 1421296_at 1422344_s_at | 1347 | 2.685 | -0.0188 | No | ||
5 | ITGA9 | 1420860_at 1450029_s_at 1460285_at | 1491 | 2.530 | -0.0170 | No | ||
6 | TANK | 1421640_a_at 1441513_at 1459668_at | 1645 | 2.397 | -0.0162 | No | ||
7 | RAP1A | 1424139_at | 1761 | 2.307 | -0.0139 | No | ||
8 | ITGA7 | 1418393_a_at | 2407 | 1.949 | -0.0371 | No | ||
9 | NCK1 | 1421487_a_at 1424543_at 1447271_at | 2432 | 1.934 | -0.0318 | No | ||
10 | MCC | 1438081_at 1442741_at 1442892_at 1459524_at 1459752_at | 2521 | 1.894 | -0.0296 | No | ||
11 | ABL1 | 1423999_at 1441291_at 1444134_at 1445153_at | 2923 | 1.744 | -0.0423 | No | ||
12 | RASA1 | 1426476_at 1426477_at 1426478_at 1438998_at | 3122 | 1.674 | -0.0458 | No | ||
13 | WNT1 | 1425377_at | 3150 | 1.664 | -0.0416 | No | ||
14 | GRB14 | 1417673_at 1457526_at | 3285 | 1.626 | -0.0424 | No | ||
15 | PTCH2 | 1422655_at | 3386 | 1.593 | -0.0417 | No | ||
16 | ITGB5 | 1417533_a_at 1417534_at 1456133_x_at 1456195_x_at | 3397 | 1.591 | -0.0370 | No | ||
17 | MAP3K12 | 1417115_at 1438908_at 1456565_s_at | 3462 | 1.574 | -0.0347 | No | ||
18 | CRK | 1416201_at 1425855_a_at 1436835_at 1448248_at 1460176_at | 3707 | 1.501 | -0.0410 | No | ||
19 | IRS1 | 1423104_at | 3910 | 1.444 | -0.0455 | No | ||
20 | MAPKAPK2 | 1426648_at | 4175 | 1.378 | -0.0531 | No | ||
21 | ITGA5 | 1423267_s_at 1423268_at 1457561_at 1458996_at | 4293 | 1.353 | -0.0540 | No | ||
22 | MAP3K7IP1 | 1426898_at 1447692_x_at | 4411 | 1.323 | -0.0550 | No | ||
23 | IL10 | 1450330_at | 4759 | 1.246 | -0.0669 | No | ||
24 | IFNB1 | 1422305_at | 4823 | 1.233 | -0.0657 | No | ||
25 | AKT1 | 1416657_at 1425711_a_at 1440950_at 1442759_at | 5061 | 1.188 | -0.0727 | No | ||
26 | NF1 | 1438067_at 1441523_at 1443097_at 1452525_a_at | 5114 | 1.180 | -0.0712 | No | ||
27 | CXCL2 | 1449984_at | 5274 | 1.148 | -0.0747 | No | ||
28 | ITGA2 | 1450501_at | 5607 | 1.088 | -0.0863 | No | ||
29 | ARHGAP6 | 1417704_a_at 1451867_x_at 1456333_a_at | 5706 | 1.071 | -0.0873 | No | ||
30 | ERG | 1425370_a_at 1440244_at | 5783 | 1.060 | -0.0873 | No | ||
31 | MAP2K2 | 1415974_at 1443436_at 1460636_at | 5916 | 1.039 | -0.0900 | No | ||
32 | MAPK13 | 1448871_at | 5959 | 1.032 | -0.0885 | No | ||
33 | RAN | 1443131_at 1446819_at 1447478_at 1460551_at | 6151 | 1.002 | -0.0940 | No | ||
34 | IL13 | 1420802_at | 6196 | 0.998 | -0.0927 | No | ||
35 | SHC1 | 1422853_at 1422854_at | 6567 | 0.943 | -0.1066 | No | ||
36 | MAS1 | 1422936_at 1447026_at | 6599 | 0.938 | -0.1049 | No | ||
37 | IFNG | 1425947_at | 6815 | 0.904 | -0.1118 | No | ||
38 | CALM1 | 1417365_a_at 1417366_s_at 1433592_at 1454611_a_at 1455571_x_at | 6826 | 0.902 | -0.1093 | No | ||
39 | IFNAR2 | 1427691_a_at 1440169_x_at 1451462_a_at | 6895 | 0.892 | -0.1095 | No | ||
40 | INHA | 1422728_at | 6908 | 0.890 | -0.1071 | No | ||
41 | ITGA3 | 1421997_s_at 1455158_at 1460305_at | 7115 | 0.857 | -0.1137 | No | ||
42 | HRAS | 1422407_s_at 1424132_at | 7380 | 0.815 | -0.1232 | No | ||
43 | JAG2 | 1426430_at 1426431_at | 7384 | 0.814 | -0.1206 | No | ||
44 | JAK1 | 1433803_at 1433804_at 1433805_at | 7449 | 0.803 | -0.1209 | No | ||
45 | DLG1 | 1415691_at 1445798_at 1450768_at 1459635_at | 8048 | 0.719 | -0.1460 | No | ||
46 | BTK | 1422755_at | 8127 | 0.705 | -0.1473 | No | ||
47 | MAPK12 | 1447823_x_at 1449283_a_at | 8129 | 0.705 | -0.1450 | No | ||
48 | SFN | 1448612_at | 8206 | 0.692 | -0.1462 | No | ||
49 | ITGA1 | 1439713_at 1446569_at 1455251_at | 8289 | 0.679 | -0.1478 | No | ||
50 | CXCL12 | 1417574_at 1439084_at 1448823_at | 8426 | 0.660 | -0.1518 | No | ||
51 | ARHGEF16 | 1427386_at | 8682 | 0.622 | -0.1615 | No | ||
52 | SKIL | 1422054_a_at 1452214_at | 9124 | 0.557 | -0.1799 | No | ||
53 | TNF | 1419607_at | 9533 | 0.499 | -0.1970 | No | ||
54 | TTK | 1442594_at 1449171_at | 9613 | 0.489 | -0.1990 | No | ||
55 | MAPK4 | 1435367_at | 9647 | 0.483 | -0.1990 | No | ||
56 | AKAP13 | 1430445_at 1433722_at 1436933_at 1439254_at 1440392_at 1440977_at 1443923_at 1445311_at 1447663_at | 10080 | 0.425 | -0.2174 | No | ||
57 | IGFBP3 | 1423062_at 1458268_s_at | 10312 | 0.395 | -0.2267 | No | ||
58 | IL1B | 1449399_a_at | 10345 | 0.391 | -0.2269 | No | ||
59 | PTPRK | 1423277_at 1423278_at 1431680_a_at 1441276_at 1441277_s_at 1441644_at 1443491_at 1443699_at 1444763_at | 10545 | 0.361 | -0.2349 | No | ||
60 | IFNGR1 | 1443602_at 1448167_at | 11070 | 0.292 | -0.2580 | No | ||
61 | ABL2 | 1445483_at 1447127_at | 11308 | 0.253 | -0.2680 | No | ||
62 | ITGAM | 1422046_at | 11391 | 0.241 | -0.2710 | No | ||
63 | WNT4 | 1450782_at | 11604 | 0.212 | -0.2801 | No | ||
64 | MAP2K5 | 1417854_at 1430180_at 1453712_a_at 1455941_s_at | 11651 | 0.204 | -0.2815 | No | ||
65 | ATM | 1421205_at 1428830_at | 11727 | 0.193 | -0.2843 | No | ||
66 | YWHAE | 1426384_a_at 1426385_x_at 1435702_s_at 1438839_a_at 1440841_at 1457173_at | 11962 | 0.157 | -0.2945 | No | ||
67 | APC | 1420956_at 1420957_at 1435543_at 1450056_at | 12128 | 0.131 | -0.3017 | No | ||
68 | TNFSF4 | 1421744_at | 12198 | 0.120 | -0.3045 | No | ||
69 | IGFBP1 | 1418918_at | 12408 | 0.090 | -0.3138 | No | ||
70 | MAP2K3 | 1425456_a_at 1451714_a_at | 12419 | 0.089 | -0.3139 | No | ||
71 | MYD88 | 1419272_at | 12479 | 0.079 | -0.3164 | No | ||
72 | GRB7 | 1448227_at | 12679 | 0.051 | -0.3254 | No | ||
73 | BCR | 1427265_at 1452368_at 1455564_at | 12826 | 0.029 | -0.3320 | No | ||
74 | JAG1 | 1421105_at 1421106_at 1434070_at | 12920 | 0.013 | -0.3362 | No | ||
75 | IL15 | 1418219_at | 12987 | 0.000 | -0.3392 | No | ||
76 | ITGAV | 1421198_at 1432296_a_at 1432678_at 1432679_at 1452784_at | 13224 | -0.041 | -0.3499 | No | ||
77 | NOTCH4 | 1436901_at 1449146_at 1456263_at | 13241 | -0.044 | -0.3505 | No | ||
78 | ITGAX | 1419128_at | 13311 | -0.055 | -0.3535 | No | ||
79 | VIPR1 | 1423004_at | 13594 | -0.102 | -0.3661 | No | ||
80 | SYK | 1418261_at 1418262_at 1425797_a_at 1457239_at | 13945 | -0.167 | -0.3817 | No | ||
81 | NRAS | 1422688_a_at 1454060_a_at | 14223 | -0.219 | -0.3937 | No | ||
82 | WNT5A | 1436791_at 1448818_at 1456976_at | 14467 | -0.265 | -0.4040 | No | ||
83 | CTNNB1 | 1420811_a_at 1430533_a_at 1450008_a_at | 14530 | -0.275 | -0.4059 | No | ||
84 | BCL10 | 1418970_a_at 1418971_x_at 1418972_at 1443524_x_at | 14734 | -0.314 | -0.4142 | No | ||
85 | MAPKAPK5 | 1417016_at 1439828_at | 15041 | -0.376 | -0.4270 | No | ||
86 | FYN | 1417558_at 1441647_at 1448765_at | 15050 | -0.377 | -0.4262 | No | ||
87 | ARHGEF12 | 1423902_s_at 1446965_at 1451159_at 1453853_a_at | 15314 | -0.431 | -0.4368 | No | ||
88 | TYRO3 | 1425248_a_at 1425249_a_at | 15357 | -0.445 | -0.4373 | No | ||
89 | AKT2 | 1421324_a_at 1424480_s_at 1455703_at | 15664 | -0.524 | -0.4496 | No | ||
90 | MUSK | 1450511_at | 15782 | -0.551 | -0.4532 | No | ||
91 | CXCL1 | 1419209_at 1441855_x_at 1457644_s_at | 15891 | -0.575 | -0.4562 | No | ||
92 | ITGB1 | 1426918_at 1426919_at 1426920_x_at 1427771_x_at 1438119_at 1452545_a_at | 15899 | -0.576 | -0.4547 | No | ||
93 | ROS1 | 1425970_a_at | 15902 | -0.577 | -0.4529 | No | ||
94 | BRAF | 1425693_at 1435434_at 1435480_at 1442749_at 1445786_at 1447940_a_at 1447941_x_at 1456505_at 1458641_at | 15936 | -0.585 | -0.4524 | No | ||
95 | TRAF6 | 1421376_at 1421377_at 1435350_at 1443288_at 1446940_at 1446977_at | 15940 | -0.585 | -0.4507 | No | ||
96 | WNT2 | 1449425_at | 16013 | -0.605 | -0.4520 | No | ||
97 | IL2RB | 1417546_at 1448759_at 1459870_x_at | 16022 | -0.607 | -0.4503 | No | ||
98 | ROCK1 | 1423444_at 1423445_at 1441162_at 1446518_at 1450994_at 1460729_at | 16058 | -0.618 | -0.4499 | No | ||
99 | MAPK9 | 1421876_at 1421877_at 1421878_at | 16335 | -0.696 | -0.4603 | No | ||
100 | SUFU | 1420848_at 1431713_at 1440004_at 1446489_at | 16364 | -0.706 | -0.4593 | No | ||
101 | ITGB8 | 1436223_at | 16396 | -0.713 | -0.4583 | No | ||
102 | MAP2K1 | 1416351_at | 16403 | -0.715 | -0.4562 | No | ||
103 | REL | 1420710_at | 16407 | -0.716 | -0.4540 | No | ||
104 | ITGB4 | 1427387_a_at | 16485 | -0.741 | -0.4551 | No | ||
105 | TIAM1 | 1418057_at 1444373_at 1453887_a_at | 16695 | -0.808 | -0.4621 | No | ||
106 | PTEN | 1422553_at 1441593_at 1444325_at 1450655_at 1454722_at 1455728_at 1457493_at | 16734 | -0.818 | -0.4611 | No | ||
107 | ZAP70 | 1422701_at 1439749_at 1440178_x_at | 16831 | -0.851 | -0.4627 | No | ||
108 | PDPK1 | 1415729_at 1416501_at 1459775_at 1459776_x_at | 16862 | -0.858 | -0.4613 | No | ||
109 | MPL | 1421461_at 1451919_a_at | 16877 | -0.862 | -0.4591 | No | ||
110 | SRC | 1423240_at 1450918_s_at | 16997 | -0.899 | -0.4616 | No | ||
111 | SOS1 | 1421884_at 1421885_at 1421886_at | 17029 | -0.911 | -0.4600 | No | ||
112 | SMO | 1427048_at 1427049_s_at 1442215_at | 17249 | -0.982 | -0.4668 | No | ||
113 | JAK3 | 1425750_a_at 1446515_at | 17349 | -1.014 | -0.4680 | No | ||
114 | RGS16 | 1426037_a_at 1451452_a_at 1455265_a_at | 17404 | -1.031 | -0.4671 | No | ||
115 | MAP3K8 | 1419208_at | 17444 | -1.043 | -0.4655 | No | ||
116 | PIK3CG | 1422707_at 1422708_at | 17754 | -1.177 | -0.4758 | No | ||
117 | DGKG | 1419756_at 1431167_at 1449584_at | 17873 | -1.224 | -0.4772 | No | ||
118 | NOTCH3 | 1421964_at 1421965_s_at 1443300_at | 17962 | -1.262 | -0.4770 | No | ||
119 | MKNK1 | 1417630_at 1417631_at 1454119_at | 18221 | -1.375 | -0.4844 | Yes | ||
120 | TNFSF13 | 1445227_at | 18246 | -1.386 | -0.4809 | Yes | ||
121 | IL18R1 | 1421628_at | 18315 | -1.425 | -0.4793 | Yes | ||
122 | PTK2B | 1434653_at 1442437_at 1442927_at | 18431 | -1.478 | -0.4797 | Yes | ||
123 | AXL | 1423586_at 1438621_x_at | 18607 | -1.555 | -0.4827 | Yes | ||
124 | GNB1 | 1417432_a_at 1425908_at 1454696_at 1459442_at | 18610 | -1.556 | -0.4776 | Yes | ||
125 | IL12RB1 | 1418166_at | 18761 | -1.646 | -0.4791 | Yes | ||
126 | MAPK11 | 1421925_at 1421926_at | 18775 | -1.658 | -0.4742 | Yes | ||
127 | AXIN2 | 1421341_at 1436845_at | 18820 | -1.680 | -0.4707 | Yes | ||
128 | CAMK4 | 1421941_at 1426167_a_at 1439843_at 1442822_at 1452572_at | 18892 | -1.712 | -0.4683 | Yes | ||
129 | STAT6 | 1421708_a_at 1426353_at | 18962 | -1.762 | -0.4657 | Yes | ||
130 | MAPK1 | 1419568_at 1426585_s_at 1442876_at 1453104_at | 18978 | -1.781 | -0.4605 | Yes | ||
131 | ITGB3 | 1421511_at 1455257_at | 19191 | -1.928 | -0.4639 | Yes | ||
132 | TYK2 | 1417306_at | 19261 | -1.986 | -0.4605 | Yes | ||
133 | TRAF3 | 1418587_at 1444758_at 1449149_at | 19295 | -2.005 | -0.4554 | Yes | ||
134 | TNFRSF1B | 1418099_at 1448951_at | 19320 | -2.022 | -0.4498 | Yes | ||
135 | ITGA4 | 1421194_at 1427615_at 1446350_at 1450155_at 1456498_at 1457376_at | 19330 | -2.030 | -0.4436 | Yes | ||
136 | MAP3K4 | 1421450_a_at 1447667_x_at 1450253_a_at 1459800_s_at | 19373 | -2.056 | -0.4387 | Yes | ||
137 | IQGAP2 | 1433885_at 1459894_at | 19401 | -2.070 | -0.4331 | Yes | ||
138 | MAPK7 | 1418060_a_at | 19440 | -2.094 | -0.4280 | Yes | ||
139 | RALBP1 | 1417248_at 1448634_at | 19552 | -2.164 | -0.4259 | Yes | ||
140 | PIK3C3 | 1425580_a_at | 19610 | -2.207 | -0.4213 | Yes | ||
141 | STAT5A | 1421469_a_at 1450259_a_at | 19715 | -2.299 | -0.4185 | Yes | ||
142 | ARHGAP1 | 1424307_at 1451309_at | 19996 | -2.579 | -0.4229 | Yes | ||
143 | MAP3K14 | 1422999_at 1434364_at | 20053 | -2.632 | -0.4167 | Yes | ||
144 | ITGB7 | 1418741_at | 20104 | -2.701 | -0.4101 | Yes | ||
145 | DGKQ | 1437000_at | 20391 | -3.015 | -0.4133 | Yes | ||
146 | MAP2K4 | 1426233_at 1442679_at 1451982_at | 20425 | -3.061 | -0.4048 | Yes | ||
147 | IRS2 | 1443969_at | 20429 | -3.064 | -0.3948 | Yes | ||
148 | ILK | 1449942_a_at | 20466 | -3.107 | -0.3862 | Yes | ||
149 | IKBKG | 1421208_at 1421209_s_at 1435646_at 1435647_at 1450161_at 1454690_at | 20492 | -3.141 | -0.3770 | Yes | ||
150 | STAT3 | 1424272_at 1426587_a_at 1459961_a_at 1460700_at | 20682 | -3.421 | -0.3744 | Yes | ||
151 | BIRC2 | 1418854_at | 20809 | -3.626 | -0.3683 | Yes | ||
152 | STAT1 | 1420915_at 1440481_at 1450033_a_at 1450034_at | 20879 | -3.726 | -0.3591 | Yes | ||
153 | MAP2K6 | 1426850_a_at 1459292_at | 20947 | -3.821 | -0.3496 | Yes | ||
154 | RELA | 1419536_a_at | 20962 | -3.850 | -0.3376 | Yes | ||
155 | MAP2K7 | 1421416_at 1425393_a_at 1425512_at 1425513_at 1440442_at 1451736_a_at 1457182_at | 20978 | -3.880 | -0.3255 | Yes | ||
156 | DGKA | 1418578_at | 21145 | -4.248 | -0.3191 | Yes | ||
157 | TRAF1 | 1423602_at 1445452_at | 21192 | -4.381 | -0.3068 | Yes | ||
158 | RAF1 | 1416078_s_at 1425419_a_at | 21295 | -4.634 | -0.2962 | Yes | ||
159 | ITGA6 | 1422444_at 1422445_at | 21311 | -4.680 | -0.2814 | Yes | ||
160 | ITGAE | 1447541_s_at 1449216_at | 21396 | -4.942 | -0.2690 | Yes | ||
161 | STAT5B | 1422102_a_at 1422103_a_at | 21397 | -4.949 | -0.2527 | Yes | ||
162 | MAP3K3 | 1426686_s_at 1426687_at 1436522_at | 21412 | -5.003 | -0.2368 | Yes | ||
163 | TNFRSF14 | 1452425_at | 21415 | -5.011 | -0.2204 | Yes | ||
164 | MAP4K4 | 1422615_at 1440609_at 1448050_s_at 1459912_at | 21585 | -5.843 | -0.2089 | Yes | ||
165 | IL6ST | 1421239_at 1437303_at 1452843_at 1460295_s_at | 21633 | -6.090 | -0.1910 | Yes | ||
166 | SH3BP2 | 1448328_at | 21639 | -6.137 | -0.1710 | Yes | ||
167 | VAV1 | 1422932_a_at | 21678 | -6.432 | -0.1515 | Yes | ||
168 | STAT2 | 1421911_at 1450403_at | 21693 | -6.619 | -0.1304 | Yes | ||
169 | ITGB2 | 1450678_at | 21698 | -6.716 | -0.1084 | Yes | ||
170 | RELB | 1417856_at | 21755 | -7.349 | -0.0867 | Yes | ||
171 | TNFRSF4 | 1420351_at | 21786 | -7.955 | -0.0619 | Yes | ||
172 | TNFRSF1A | 1417291_at | 21853 | -9.228 | -0.0345 | Yes | ||
173 | IFNAR1 | 1442222_at 1449026_at | 21902 | -11.581 | 0.0015 | Yes |