Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_02_ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus_repos |
| Phenotype | phenotype_ATM_minus_versus_ATM_plus.cls#ATM_minus_versus_ATM_plus_repos |
| Upregulated in class | ATM_plus |
| GeneSet | APOPTOSIS |
| Enrichment Score (ES) | -0.57807165 |
| Normalized Enrichment Score (NES) | -1.9431742 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.012183779 |
| FWER p-Value | 0.172 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CYCS | 1422484_at 1445484_at | 57 | 6.950 | 0.0385 | No | ||
| 2 | MYC | 1424942_a_at | 165 | 5.495 | 0.0661 | No | ||
| 3 | BAX | 1416837_at | 419 | 4.277 | 0.0798 | No | ||
| 4 | CHUK | 1417091_at 1428210_s_at 1451383_a_at | 1214 | 2.804 | 0.0601 | No | ||
| 5 | MAPK10 | 1437195_x_at 1448342_at 1458002_at 1458062_at 1458513_at | 1309 | 2.715 | 0.0719 | No | ||
| 6 | TNFRSF10B | 1421296_at 1422344_s_at | 1347 | 2.685 | 0.0861 | No | ||
| 7 | BIRC5 | 1424278_a_at | 2548 | 1.880 | 0.0423 | No | ||
| 8 | IRF2 | 1418265_s_at 1447527_at | 2722 | 1.815 | 0.0451 | No | ||
| 9 | CASP8 | 1424552_at | 3709 | 1.500 | 0.0089 | No | ||
| 10 | BNIP3L | 1416922_a_at 1416923_a_at 1448525_a_at | 3875 | 1.451 | 0.0100 | No | ||
| 11 | IKBKB | 1426207_at 1426333_a_at 1432275_at 1445141_at 1454184_a_at | 3962 | 1.430 | 0.0145 | No | ||
| 12 | NFKBIE | 1431843_a_at 1458299_s_at | 4996 | 1.199 | -0.0256 | No | ||
| 13 | TNFRSF21 | 1422740_at 1450731_s_at | 5865 | 1.046 | -0.0591 | No | ||
| 14 | BAD | 1416582_a_at 1416583_at | 6759 | 0.912 | -0.0946 | No | ||
| 15 | TP53 | 1426538_a_at 1427739_a_at 1438808_at 1457623_x_at 1459780_at 1459781_x_at | 7499 | 0.796 | -0.1237 | No | ||
| 16 | HELLS | 1417541_at 1430139_at 1453361_at | 8381 | 0.666 | -0.1600 | No | ||
| 17 | CASP1 | 1449265_at | 8639 | 0.628 | -0.1680 | No | ||
| 18 | HRK | 1439854_at 1450366_at | 8899 | 0.591 | -0.1764 | No | ||
| 19 | NFKBIB | 1421266_s_at 1446718_at | 9147 | 0.553 | -0.1844 | No | ||
| 20 | CASP4 | 1449591_at | 9293 | 0.532 | -0.1879 | No | ||
| 21 | TNF | 1419607_at | 9533 | 0.499 | -0.1959 | No | ||
| 22 | TNFSF10 | 1420412_at 1439680_at 1459913_at | 10242 | 0.404 | -0.2259 | No | ||
| 23 | NFKBIA | 1420088_at 1420089_at 1438157_s_at 1448306_at 1449731_s_at | 10443 | 0.375 | -0.2328 | No | ||
| 24 | CASP3 | 1426165_a_at 1430192_at 1449839_at | 10481 | 0.370 | -0.2323 | No | ||
| 25 | IRF3 | 1416898_a_at 1426111_x_at 1435271_at 1438721_a_at | 11801 | 0.182 | -0.2915 | No | ||
| 26 | NFKB1 | 1427705_a_at 1442949_at | 11848 | 0.175 | -0.2926 | No | ||
| 27 | BCL2L1 | 1420887_a_at 1420888_at 1426050_at 1426191_a_at | 12302 | 0.105 | -0.3127 | No | ||
| 28 | IRF4 | 1421173_at 1421174_at | 12762 | 0.038 | -0.3334 | No | ||
| 29 | IRF5 | 1460231_at | 13511 | -0.089 | -0.3671 | No | ||
| 30 | BID | 1417045_at 1447873_x_at 1448560_at | 14384 | -0.248 | -0.4055 | No | ||
| 31 | FASLG | 1418803_a_at 1449235_at | 14646 | -0.298 | -0.4157 | No | ||
| 32 | BCL2 | 1422938_at 1427818_at 1437122_at 1440770_at 1443837_x_at 1457687_at | 15444 | -0.468 | -0.4494 | No | ||
| 33 | GZMB | 1419060_at | 15478 | -0.475 | -0.4481 | No | ||
| 34 | MDM2 | 1423605_a_at 1427718_a_at 1457929_at | 16738 | -0.819 | -0.5008 | No | ||
| 35 | TRADD | 1429117_at 1439910_a_at 1452622_a_at | 16801 | -0.841 | -0.4987 | No | ||
| 36 | JUN | 1417409_at 1448694_at | 16926 | -0.879 | -0.4991 | No | ||
| 37 | RIPK1 | 1419508_at 1439273_at 1449485_at | 17018 | -0.908 | -0.4979 | No | ||
| 38 | BIRC3 | 1421392_a_at 1425223_at | 17639 | -1.121 | -0.5196 | No | ||
| 39 | CASP9 | 1426125_a_at 1437537_at 1457816_at | 17786 | -1.190 | -0.5193 | No | ||
| 40 | FADD | 1416888_at 1446499_at | 18889 | -1.709 | -0.5596 | No | ||
| 41 | TRAF3 | 1418587_at 1444758_at 1449149_at | 19295 | -2.005 | -0.5662 | Yes | ||
| 42 | TNFRSF1B | 1418099_at 1448951_at | 19320 | -2.022 | -0.5553 | Yes | ||
| 43 | CASP2 | 1448165_at | 19399 | -2.069 | -0.5467 | Yes | ||
| 44 | BIRC4 | 1421394_a_at 1426636_a_at 1437533_at 1440351_at 1450231_a_at 1450232_at 1456088_at | 19429 | -2.090 | -0.5356 | Yes | ||
| 45 | DFFB | 1421229_at 1437051_at | 19782 | -2.361 | -0.5378 | Yes | ||
| 46 | MAP2K4 | 1426233_at 1442679_at 1451982_at | 20425 | -3.061 | -0.5490 | Yes | ||
| 47 | IKBKG | 1421208_at 1421209_s_at 1435646_at 1435647_at 1450161_at 1454690_at | 20492 | -3.141 | -0.5335 | Yes | ||
| 48 | IRF1 | 1448436_a_at | 20504 | -3.165 | -0.5152 | Yes | ||
| 49 | APAF1 | 1450223_at | 20613 | -3.326 | -0.5005 | Yes | ||
| 50 | LTA | 1420353_at | 20698 | -3.438 | -0.4840 | Yes | ||
| 51 | FAS | 1460251_at | 20729 | -3.489 | -0.4647 | Yes | ||
| 52 | IRF6 | 1418301_at | 20796 | -3.593 | -0.4465 | Yes | ||
| 53 | BIRC2 | 1418854_at | 20809 | -3.626 | -0.4256 | Yes | ||
| 54 | BCL2L11 | 1426334_a_at 1435448_at 1435449_at 1456005_a_at 1456006_at 1459794_at | 20953 | -3.830 | -0.4095 | Yes | ||
| 55 | RELA | 1419536_a_at | 20962 | -3.850 | -0.3871 | Yes | ||
| 56 | TNFRSF25 | 1422231_a_at | 21027 | -3.963 | -0.3666 | Yes | ||
| 57 | PRF1 | 1451862_a_at | 21079 | -4.092 | -0.3447 | Yes | ||
| 58 | TRAF2 | 1451233_at | 21088 | -4.116 | -0.3207 | Yes | ||
| 59 | TRAF1 | 1423602_at 1445452_at | 21192 | -4.381 | -0.2995 | Yes | ||
| 60 | IRF7 | 1417244_a_at | 21563 | -5.713 | -0.2826 | Yes | ||
| 61 | MAP3K1 | 1424850_at | 21629 | -6.080 | -0.2497 | Yes | ||
| 62 | TNFRSF1A | 1417291_at | 21853 | -9.228 | -0.2053 | Yes | ||
| 63 | CASP7 | 1426062_a_at 1448659_at | 21890 | -11.018 | -0.1417 | Yes | ||
| 64 | DFFA | 1450885_at 1457564_at | 21920 | -12.111 | -0.0714 | Yes | ||
| 65 | CASP6 | 1415995_at 1458715_at | 21923 | -12.179 | 0.0005 | Yes |
