Details for gene set NEGATIVE_REGULATION_OF

Table: GSEA Results Summary

Dataset	Set_01_SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls #SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls #SCID_versus_ATM_plus_repos
Phenotype	phenotype_SCID_versus_ATM_plus.cls#SCID_versus_ATM_plus_repos
Upregulated in class	ATM_plus
GeneSet	NEGATIVE_REGULATION_OF_TRANSCRIPTION
Enrichment Score (ES)	-0.44929162
Normalized Enrichment Score (NES)	-1.7347788
Nominal p-value	0.0
FDR q-value	0.21891211
FWER p-Value	0.945

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	DRAP1	1451676_at	266	4.329	0.0096	No
2	TIMELESS	1417586_at 1417587_at	369	3.824	0.0242	No
3	HELLS	1417541_at 1430139_at 1453361_at	1345	2.097	-0.0100	No
4	NR0B1	1417760_at	1425	2.039	-0.0034	No
5	GATAD2A	1423992_at 1445239_at 1451197_s_at 1451198_at 1455505_at	1493	2.004	0.0036	No
6	MDM4	1419558_at 1453982_at 1460542_s_at	1804	1.844	-0.0013	No
7	EPC1	1418850_at 1429914_at 1440198_at 1440742_at 1442279_at 1443675_at 1458315_at	2019	1.711	-0.0025	No
8	PHB	1435144_at 1442233_at 1448563_at	2079	1.682	0.0032	No
9	HDAC8	1428933_at	2268	1.584	0.0026	No
10	HEXIM2	1429025_a_at 1429026_at	2286	1.576	0.0097	No
11	SMAD3	1450471_at 1450472_s_at 1454960_at	2317	1.556	0.0162	No
12	GFI1B	1420399_at	2375	1.534	0.0213	No
13	FOXD3	1422210_at	2547	1.454	0.0207	No
14	PHF21A	1418390_at 1418391_at 1439123_at 1444679_at 1458166_at	2628	1.427	0.0242	No
15	KLF11	1437241_at	2839	1.355	0.0214	No
16	BRCA1	1424629_at 1424630_a_at 1427698_at 1443763_at 1451417_at	2922	1.334	0.0244	No
17	VPS72	1418284_at	2980	1.317	0.0284	No
18	E2F6	1437914_at 1448835_at	3016	1.307	0.0334	No
19	PIAS4	1418861_at 1455394_at	3080	1.289	0.0370	No
20	LANCL2	1420856_a_at 1420857_at 1450028_a_at	3181	1.260	0.0387	No
21	TNP1	1415924_at 1438632_x_at	3187	1.258	0.0448	No
22	DMBX1	1460277_at	3629	1.159	0.0304	No
23	GLIS1	1425423_at	3774	1.135	0.0295	No
24	ID1	1425895_a_at	3846	1.120	0.0319	No
25	PRDM1	1420425_at 1444997_at	4071	1.083	0.0271	No
26	WWP1	1427097_at 1427098_at 1446364_at 1446853_at 1452299_at	4708	1.000	0.0029	No
27	ID4	1423259_at 1423260_at 1438441_at 1450928_at	4709	1.000	0.0079	No
28	HMGB1	1416176_at 1425048_a_at 1435324_x_at	4761	0.994	0.0106	No
29	GLIS2	1416598_at 1416599_at	5025	0.962	0.0034	No
30	MECP2	1438930_s_at 1449266_at 1460246_at	5194	0.938	0.0004	No
31	NSD1	1420881_at 1435088_at 1440972_at 1456916_at	5394	0.909	-0.0042	No
32	RYBP	1421111_at	5493	0.896	-0.0042	No
33	SNAI2	1418673_at 1447643_x_at	5774	0.858	-0.0127	No
34	TCEAL1	1424634_at	6438	0.776	-0.0392	No
35	EREG	1419431_at	6521	0.765	-0.0391	No
36	TWIST1	1418733_at	6685	0.746	-0.0429	No
37	ERN2	1450139_at	6844	0.729	-0.0464	No
38	ENO1	1419023_x_at	6937	0.717	-0.0471	No
39	TRIM27	1415815_at 1438376_s_at 1441051_at 1448101_s_at 1456375_x_at 1457051_at	7117	0.697	-0.0518	No
40	TLE1	1422751_at 1434033_at	7248	0.683	-0.0543	No
41	E2F1	1417878_at 1431875_a_at 1447840_x_at	7270	0.679	-0.0518	No
42	PPARD	1425703_at 1439797_at	7462	0.655	-0.0573	No
43	RUNX2	1424704_at 1425389_a_at 1426034_a_at	7633	0.638	-0.0619	No
44	SIRT1	1418640_at 1458538_at	7772	0.623	-0.0651	No
45	NKX2-5	1449566_at	7848	0.616	-0.0654	No
46	NR1I2	1425723_at 1451807_at	7903	0.610	-0.0649	No
47	ILF3	1422546_at 1436802_at 1460669_at	8047	0.595	-0.0684	No
48	PAWR	1444808_at 1445390_at	8317	0.568	-0.0779	No
49	GLI2	1446086_s_at 1459211_at	8601	0.539	-0.0882	No
50	HSBP1	1423906_at 1451162_at	8627	0.537	-0.0866	No
51	NDUFA13	1430713_s_at	9007	0.499	-0.1015	No
52	TNF	1419607_at	9219	0.478	-0.1088	No
53	PCGF6	1424081_at 1432108_at 1454120_a_at	9431	0.458	-0.1162	No
54	PA2G4	1420142_s_at 1423060_at 1435372_a_at 1450854_at 1460265_at	9676	0.432	-0.1252	No
55	BMP2	1423635_at	10353	0.369	-0.1544	No
56	JARID1B	1427142_s_at 1427143_at 1442278_at 1457482_at	10706	0.335	-0.1688	No
57	ATP8B1	1420075_at 1420076_at 1455396_at	11367	0.273	-0.1978	No
58	CALCA	1427355_at 1452004_at	11578	0.251	-0.2061	No
59	RSF1	1438735_at	12431	0.170	-0.2444	No
60	POU2F1	1419716_a_at 1427695_a_at 1427835_at	12497	0.165	-0.2465	No
61	RBM9	1418245_a_at 1418246_at 1418247_s_at 1434938_at	12607	0.155	-0.2508	No
62	STAT3	1424272_at 1426587_a_at 1459961_a_at 1460700_at	12643	0.151	-0.2516	No
63	ID2	1422537_a_at 1435176_a_at 1453596_at	12717	0.145	-0.2542	No
64	NR0B2	1449854_at	12761	0.141	-0.2555	No
65	NR6A1	1421515_at 1421516_at 1428825_at 1428826_at 1445872_at	13153	0.100	-0.2729	No
66	GRLF1	1434009_at 1440675_at 1442181_at	13232	0.089	-0.2761	No
67	FOSB	1422134_at	13344	0.077	-0.2808	No
68	MYST4	1423508_at 1446189_at 1447258_at 1447758_x_at	13408	0.071	-0.2833	No
69	FST	1421365_at 1434458_at	13729	0.036	-0.2978	No
70	ZBTB32	1432459_a_at 1447330_at	13735	0.035	-0.2979	No
71	SIRT5	1428915_at 1428916_s_at 1432105_at	13811	0.026	-0.3012	No
72	MYST1	1432080_s_at	13831	0.024	-0.3019	No
73	KLF12	1439846_at 1439847_s_at 1441040_at 1455521_at	13967	0.010	-0.3081	No
74	IRF2	1418265_s_at 1447527_at	14417	-0.043	-0.3285	No
75	TCF25	1424053_a_at 1437204_a_at 1437205_at 1451081_a_at 1459240_at 1460109_at	14469	-0.050	-0.3306	No
76	MDFI	1420713_a_at 1425924_at	14527	-0.057	-0.3329	No
77	BCLAF1	1428844_a_at 1428845_at 1436023_at 1438089_a_at	14729	-0.083	-0.3417	No
78	RFX3	1425413_at 1441253_at 1441702_at	14846	-0.097	-0.3466	No
79	TWIST2	1448925_at	15046	-0.124	-0.3551	No
80	FOXP3	1420765_a_at 1457082_at	15507	-0.190	-0.3752	No
81	DEDD	1432000_a_at 1434994_at 1434995_s_at	15595	-0.204	-0.3782	No
82	ZNF24	1422810_at 1426895_at 1426896_at 1430650_at 1430651_s_at 1450762_s_at	15782	-0.231	-0.3856	No
83	SIRT4	1426847_at	15851	-0.243	-0.3875	No
84	GLIS3	1430353_at 1443157_at 1443253_at	16208	-0.311	-0.4022	No
85	ATXN1	1438294_at 1445695_at 1450499_at 1457605_at	16447	-0.358	-0.4114	No
86	YAF2	1423399_a_at 1429839_a_at 1446073_at	16738	-0.430	-0.4225	No
87	NRG1	1456524_at	16777	-0.440	-0.4220	No
88	NKRF	1434398_at 1441325_at 1445983_at	16829	-0.451	-0.4221	No
89	ING4	1448054_at 1460728_s_at	16951	-0.485	-0.4252	No
90	TBX3	1437479_x_at 1439567_at 1444594_at 1445757_at 1448029_at	16977	-0.491	-0.4239	No
91	KLF4	1417394_at 1417395_at	17293	-0.578	-0.4354	No
92	PEX14	1419053_at 1458153_at	17397	-0.606	-0.4371	No
93	NR1H2	1416353_at	17509	-0.645	-0.4390	No
94	PML	1448757_at 1456103_at 1459137_at	17575	-0.667	-0.4386	No
95	CENPF	1427161_at 1452334_at 1458447_at	17679	-0.695	-0.4398	No
96	DAXX	1419026_at	17806	-0.738	-0.4419	No
97	RB1	1417850_at 1441494_at 1444400_at 1444454_at 1457447_at	17852	-0.755	-0.4402	No
98	ORC2L	1418225_at 1418226_at 1418227_at	18052	-0.830	-0.4451	Yes
99	ATF7IP	1446323_at 1449192_at 1454973_at 1459096_at	18107	-0.846	-0.4433	Yes
100	LDB1	1452024_a_at	18109	-0.846	-0.4391	Yes
101	SPI1	1418747_at	18153	-0.865	-0.4367	Yes
102	POU4F2	1437588_at	18173	-0.869	-0.4332	Yes
103	VDR	1418175_at 1418176_at	18209	-0.885	-0.4304	Yes
104	NFX1	1419752_at 1419753_at 1428248_at 1442397_at	18298	-0.913	-0.4298	Yes
105	PHF12	1434922_at 1453579_at	18315	-0.918	-0.4259	Yes
106	SNX6	1425148_a_at 1429497_s_at 1447234_s_at 1451602_at	18324	-0.920	-0.4217	Yes
107	MYST3	1436315_at 1437487_at 1446143_at 1446405_at	18378	-0.937	-0.4194	Yes
108	ARID5B	1420972_at 1420973_at 1434283_at 1442176_at 1445423_at 1456831_at 1456973_at 1457483_at 1458238_at	18637	-1.019	-0.4261	Yes
109	SLA2	1437504_at 1451492_at	18752	-1.059	-0.4260	Yes
110	ZHX3	1419791_at 1441454_at 1442963_at 1452977_at 1454289_at 1456979_at 1457710_at	18814	-1.083	-0.4234	Yes
111	ARID5A	1451340_at	18817	-1.084	-0.4180	Yes
112	SMAD2	1420634_a_at 1458304_at	19111	-1.219	-0.4253	Yes
113	GCLC	1424296_at	19122	-1.228	-0.4196	Yes
114	PER1	1449851_at	19247	-1.290	-0.4188	Yes
115	NRIP1	1418469_at 1432603_at 1434384_at 1446389_at 1447211_at 1449089_at 1454295_at	19351	-1.349	-0.4167	Yes
116	MXD4	1422574_at 1434378_a_at 1434379_at	19366	-1.356	-0.4105	Yes
117	KLF10	1416029_at	19419	-1.390	-0.4059	Yes
118	SUPT5H	1424255_at	19444	-1.406	-0.4000	Yes
119	PDCD4	1444171_at	19569	-1.485	-0.3982	Yes
120	BCOR	1428773_s_at 1429438_at 1452910_at	19579	-1.490	-0.3911	Yes
121	ZNF148	1418381_at 1427730_a_at 1436217_at 1441612_at 1441701_at 1449068_at 1449069_at 1455483_at	19615	-1.511	-0.3851	Yes
122	SMARCE1	1422675_at 1422676_at 1430822_at	19764	-1.620	-0.3837	Yes
123	SIRT2	1423507_a_at	19790	-1.641	-0.3766	Yes
124	SNW1	1429002_at 1429003_at 1459026_at	19817	-1.661	-0.3694	Yes
125	SUMO1	1438289_a_at 1444557_at 1451005_at 1456349_x_at	19865	-1.693	-0.3631	Yes
126	ZHX1	1448875_at 1458382_a_at	20011	-1.813	-0.3606	Yes
127	SIN3A	1419101_at 1419102_at 1419900_at 1449343_s_at	20139	-1.923	-0.3568	Yes
128	DR1	1416018_at 1416019_at	20155	-1.936	-0.3477	Yes
129	ELK3	1417662_at 1442986_at 1445886_at 1448797_at	20156	-1.938	-0.3379	Yes
130	IRF8	1416714_at 1448452_at	20238	-1.993	-0.3316	Yes
131	MEN1	1416347_at 1416348_at 1443826_x_at	20296	-2.021	-0.3241	Yes
132	KHDRBS1	1418628_at 1418630_at	20352	-2.058	-0.3162	Yes
133	HEXIM1	1419359_at 1425937_a_at	20443	-2.144	-0.3096	Yes
134	MDM2	1423605_a_at 1427718_a_at 1457929_at	20461	-2.164	-0.2995	Yes
135	DNMT1	1422946_a_at 1435122_x_at 1445637_at 1447877_x_at	20497	-2.200	-0.2900	Yes
136	CTCF	1418330_at 1449042_at	20645	-2.384	-0.2847	Yes
137	ZFP161	1420864_at 1420865_at 1420866_at 1437585_x_at	20730	-2.488	-0.2761	Yes
138	CSDA	1435800_a_at 1451012_a_at	20792	-2.563	-0.2660	Yes
139	ZBTB16	1419874_x_at 1427638_at 1439163_at 1445562_at 1456986_at 1459557_at	20826	-2.618	-0.2543	Yes
140	SMARCC2	1428382_at	20832	-2.626	-0.2413	Yes
141	UBP1	1455222_a_at 1460655_a_at	21046	-2.985	-0.2361	Yes
142	IRF7	1417244_a_at	21245	-3.481	-0.2276	Yes
143	ZHX2	1455210_at	21272	-3.557	-0.2109	Yes
144	SMAD4	1422485_at 1422486_a_at 1422487_at 1444205_at	21473	-4.259	-0.1987	Yes
145	HDAC5	1415743_at	21541	-4.626	-0.1784	Yes
146	BCL3	1418133_at	21555	-4.716	-0.1553	Yes
147	TGFB1	1420653_at 1445360_at	21716	-6.029	-0.1323	Yes
148	ARID4A	1436191_at 1438464_at 1456420_at	21755	-6.438	-0.1016	Yes
149	ZMYND11	1426531_at 1426532_at 1436153_a_at 1444461_at 1446182_at	21792	-6.999	-0.0681	Yes
150	ID3	1416630_at	21832	-7.406	-0.0326	Yes
151	BCL6	1421818_at 1450381_a_at	21833	-7.407	0.0047	Yes