Details for gene set DEFENSE

Table: GSEA Results Summary

Dataset	Set_01_SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls #SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls #SCID_versus_ATM_plus_repos
Phenotype	phenotype_SCID_versus_ATM_plus.cls#SCID_versus_ATM_plus_repos
Upregulated in class	ATM_plus
GeneSet	DEFENSE_RESPONSE
Enrichment Score (ES)	-0.43762743
Normalized Enrichment Score (NES)	-1.7687615
Nominal p-value	0.0
FDR q-value	0.21248071
FWER p-Value	0.85

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PTPRC	1422124_a_at 1440165_at	195	4.864	0.0080	No
2	CD5L	1449193_at	214	4.670	0.0235	No
3	CEBPB	1418901_at 1427844_a_at	270	4.311	0.0360	No
4	CEBPG	1425261_at 1425262_at 1451639_at	326	3.958	0.0473	No
5	TARBP2	1423616_at 1438952_x_at	616	3.149	0.0450	No
6	SCYE1	1416486_at	965	2.494	0.0377	No
7	LGALS3BP	1448380_at	1099	2.320	0.0397	No
8	MX2	1419676_at	1129	2.284	0.0463	No
9	TPST1	1421733_a_at	1325	2.112	0.0447	No
10	MX1	1451905_a_at	1408	2.049	0.0481	No
11	PTX3	1418666_at 1456903_at	1423	2.040	0.0546	No
12	TLR6	1421352_at	1469	2.012	0.0595	No
13	STAB1	1450199_a_at	1601	1.953	0.0603	No
14	IL5	1425546_a_at 1442049_at 1450550_at	1813	1.839	0.0570	No
15	TIAL1	1421148_a_at 1426352_s_at 1446713_at 1452821_at 1455675_a_at 1455676_x_at	1928	1.769	0.0580	No
16	TCIRG1	1420635_a_at	1929	1.769	0.0642	No
17	AHSG	1455093_a_at	1979	1.741	0.0680	No
18	ADORA2A	1427519_at 1460710_at	2026	1.709	0.0718	No
19	TPSAB1	1426175_a_at	2431	1.509	0.0585	No
20	TACR1	1422282_at	2549	1.453	0.0582	No
21	CCL3	1419561_at	2591	1.439	0.0613	No
22	AGER	1420428_at 1441958_s_at	2624	1.428	0.0648	No
23	C3AR1	1419482_at 1419483_at 1442082_at	2787	1.376	0.0622	No
24	FOSL1	1417487_at 1417488_at	2872	1.348	0.0630	No
25	PTAFR	1427871_at 1427872_at	2975	1.319	0.0629	No
26	CXCL1	1419209_at 1441855_x_at 1457644_s_at	3009	1.309	0.0660	No
27	C5AR1	1422190_at 1439902_at	3157	1.265	0.0637	No
28	PLA2G2E	1420674_at	3170	1.261	0.0675	No
29	IL12A	1425454_a_at	3348	1.222	0.0636	No
30	FOXN1	1450508_at 1456815_at	3410	1.210	0.0650	No
31	PLA2G7	1430700_a_at	3424	1.207	0.0687	No
32	IL17RB	1420678_a_at	4060	1.085	0.0432	No
33	IL4	1449864_at	4073	1.082	0.0465	No
34	ITK	1417171_at 1430833_at 1452518_a_at 1456836_at 1457120_at	4530	1.018	0.0290	No
35	HDAC9	1421306_a_at 1434572_at	4559	1.014	0.0313	No
36	TLR3	1422781_at 1422782_s_at	4575	1.012	0.0341	No
37	IL9	1450565_at	4771	0.992	0.0286	No
38	WFDC12	1449191_at	5149	0.945	0.0146	No
39	C2	1416051_at 1441912_x_at 1457664_x_at	5321	0.921	0.0099	No
40	INHBB	1426858_at 1426859_at	5330	0.920	0.0127	No
41	IL18RAP	1421291_at 1456545_at	5542	0.890	0.0061	No
42	CBARA1	1439501_at 1443340_at 1451207_at 1459525_at	5645	0.877	0.0045	No
43	IL1RAP	1421843_at 1439697_at 1442614_at 1449585_at	5971	0.835	-0.0075	No
44	CCR5	1422259_a_at 1422260_x_at 1424727_at	6179	0.807	-0.0142	No
45	OR2H2	1460313_at	6279	0.795	-0.0160	No
46	SCG2	1450708_at	6330	0.789	-0.0156	No
47	GHSR	1446756_at	6469	0.771	-0.0192	No
48	EREG	1419431_at	6521	0.765	-0.0189	No
49	DCDC2	1441503_at	6532	0.764	-0.0167	No
50	CXCL2	1449984_at	6533	0.764	-0.0140	No
51	KLRC3	1421794_at	6670	0.748	-0.0177	No
52	CD81	1416330_at	6860	0.727	-0.0238	No
53	GHRL	1448980_at	6974	0.714	-0.0265	No
54	ABCF1	1420157_s_at 1420158_s_at 1426921_at 1427444_at 1452236_at 1452429_s_at	7177	0.691	-0.0334	No
55	CCL24	1450488_at	7417	0.661	-0.0421	No
56	ELF3	1416916_at	7458	0.656	-0.0417	No
57	CLEC5A	1421366_at	7473	0.654	-0.0400	No
58	TLR8	1450267_at	7479	0.653	-0.0380	No
59	LBP	1448550_at	7751	0.625	-0.0483	No
60	KNG1	1416676_at 1426045_at	7968	0.603	-0.0561	No
61	APCS	1419059_at	8037	0.596	-0.0571	No
62	COLEC12	1419693_at 1446535_at	8411	0.559	-0.0724	No
63	STAB2	1419423_at	8997	0.500	-0.0975	No
64	RIPK2	1421236_at 1450173_at	9165	0.482	-0.1035	No
65	PLA2G2D	1418987_at 1454157_a_at	9262	0.475	-0.1063	No
66	ANKRD1	1420991_at 1420992_at	9269	0.475	-0.1049	No
67	CX3CL1	1415803_at 1415804_at 1421610_at 1441884_x_at	9497	0.451	-0.1138	No
68	IFNA2	1423028_at	9546	0.446	-0.1144	No
69	CCL11	1417789_at	9810	0.420	-0.1251	No
70	AOX1	1419435_at	10031	0.398	-0.1338	No
71	IL13	1420802_at	10032	0.398	-0.1324	No
72	UMOD	1426252_a_at 1456306_a_at	10186	0.384	-0.1381	No
73	FPRL1	1421661_at 1450583_s_at	10203	0.383	-0.1375	No
74	SPACA3	1429970_at 1443825_x_at	10331	0.371	-0.1421	No
75	ORM2	1420438_at	10394	0.366	-0.1436	No
76	IL20	1421608_at	10525	0.354	-0.1484	No
77	NFATC4	1423380_s_at 1432821_at 1454369_a_at	10798	0.325	-0.1598	No
78	ORM1	1451054_at	10884	0.317	-0.1626	No
79	CHRNA7	1440681_at 1450299_at	10906	0.316	-0.1624	No
80	DEFB1	1419491_at 1419492_s_at	10993	0.309	-0.1653	No
81	BNIP3	1422470_at	11032	0.306	-0.1660	No
82	ADORA1	1427331_at 1435495_at	11175	0.294	-0.1715	No
83	BECN1	1430358_at 1435219_x_at 1437006_x_at 1439405_x_at 1455880_s_at 1460320_at	11272	0.284	-0.1749	No
84	IL28RA	1446908_at 1460598_at	11327	0.278	-0.1765	No
85	KLRC2	1450304_at	11534	0.257	-0.1850	No
86	CFHR1	1419436_at	11577	0.251	-0.1861	No
87	CLEC1B	1421182_at	11671	0.242	-0.1895	No
88	IL8RB	1421734_at	11705	0.238	-0.1902	No
89	BLNK	1451780_at	11797	0.229	-0.1936	No
90	F11R	1424595_at 1436374_x_at	11896	0.218	-0.1974	No
91	CCR2	1421186_at 1421187_at 1421188_at 1460067_at	11984	0.210	-0.2006	No
92	CAMLG	1417842_at	11988	0.209	-0.2000	No
93	TLR7	1419848_x_at 1422010_at 1449640_at	12490	0.165	-0.2225	No
94	SELE	1421712_at	12540	0.161	-0.2242	No
95	CRP	1421946_at	12604	0.155	-0.2266	No
96	EDG3	1437173_at 1438658_a_at 1460661_at	12616	0.154	-0.2265	No
97	AOAH	1450764_at 1460156_at	12651	0.150	-0.2276	No
98	CCL4	1421578_at	12786	0.139	-0.2333	No
99	CLEC1A	1456318_at 1460039_at	12788	0.139	-0.2328	No
100	TNFAIP6	1418424_at	12877	0.128	-0.2364	No
101	ALOX5AP	1452016_at 1459234_at	12889	0.128	-0.2365	No
102	IL1A	1421473_at	12916	0.125	-0.2372	No
103	AOC3	1449396_at	12999	0.116	-0.2406	No
104	MEFV	1460283_at	13113	0.104	-0.2454	No
105	NOX4	1419161_a_at 1451827_a_at	13309	0.080	-0.2541	No
106	CCR1	1419609_at 1419610_at	13355	0.076	-0.2559	No
107	CCL20	1422029_at	13409	0.070	-0.2581	No
108	CXCL11	1419697_at 1419698_at	13752	0.033	-0.2738	No
109	CYSLTR1	1418944_at 1449282_at	13885	0.019	-0.2798	No
110	INHBA	1422053_at 1458291_at	13990	0.008	-0.2845	No
111	CCL5	1418126_at	14078	-0.001	-0.2885	No
112	MBL2	1418787_at	14249	-0.022	-0.2963	No
113	IL1RL2	1434903_s_at 1450273_at	14313	-0.029	-0.2991	No
114	CHST2	1422758_at 1460070_at	14688	-0.077	-0.3160	No
115	CD19	1450570_a_at	14726	-0.083	-0.3174	No
116	XCR1	1422294_at	14891	-0.102	-0.3246	No
117	NCF2	1448561_at	14920	-0.106	-0.3255	No
118	APOA4	1417761_at 1436504_x_at	14993	-0.115	-0.3285	No
119	IL10RB	1419455_at	15132	-0.134	-0.3343	No
120	NCR1	1422089_at	15333	-0.163	-0.3430	No
121	HRH1	1419210_at 1438494_at	15548	-0.196	-0.3521	No
122	LTB4R	1420407_at	15637	-0.209	-0.3555	No
123	FAIM3	1429889_at	15831	-0.239	-0.3635	No
124	KLRG1	1420788_at	15996	-0.271	-0.3701	No
125	SFTPD	1420378_at	16076	-0.286	-0.3727	No
126	LALBA	1418363_at	16091	-0.289	-0.3724	No
127	DEFB103A	1421806_at	16117	-0.294	-0.3725	No
128	MGLL	1426785_s_at 1431331_at 1450391_a_at 1453836_a_at	16281	-0.325	-0.3789	No
129	CFP	1452279_at	16304	-0.329	-0.3787	No
130	RNASE6	1430534_at	16456	-0.360	-0.3844	No
131	DMBT1	1418287_a_at	16487	-0.366	-0.3845	No
132	CSF3R	1418806_at	16734	-0.430	-0.3943	No
133	NFKB1	1427705_a_at 1442949_at	16839	-0.453	-0.3975	No
134	CD40	1439221_s_at 1449473_s_at 1460415_a_at	16848	-0.457	-0.3963	No
135	SIGIRR	1449163_at	16868	-0.462	-0.3956	No
136	CX3CR1	1450019_at 1450020_at	16876	-0.464	-0.3943	No
137	CDO1	1448842_at	16927	-0.476	-0.3949	No
138	KCNN4	1421038_a_at 1435945_a_at	16985	-0.492	-0.3958	No
139	CCR3	1422957_at	17019	-0.499	-0.3956	No
140	MST1R	1420461_at	17027	-0.500	-0.3942	No
141	CD40LG	1422283_at	17262	-0.570	-0.4029	No
142	TFF3	1417370_at	17272	-0.572	-0.4014	No
143	CXCL10	1418930_at	17296	-0.580	-0.4004	No
144	CXCL9	1418652_at 1456907_at	17549	-0.659	-0.4097	No
145	AIF1	1418204_s_at	17668	-0.693	-0.4127	No
146	LYST	1421384_at 1425973_at 1434674_at	17847	-0.753	-0.4183	No
147	RSAD2	1421008_at 1421009_at 1436058_at	17888	-0.767	-0.4174	No
148	BCL10	1418970_a_at 1418971_x_at 1418972_at 1443524_x_at	17917	-0.775	-0.4160	No
149	NFX1	1419752_at 1419753_at 1428248_at 1442397_at	18298	-0.913	-0.4303	No
150	PRDX5	1416381_a_at	18318	-0.918	-0.4280	No
151	TYROBP	1450792_at	18347	-0.929	-0.4260	No
152	HP	1448881_at	18518	-0.987	-0.4304	No
153	IL12B	1419530_at 1449497_at	18676	-1.031	-0.4340	Yes
154	CRTAM	1449903_at	18681	-1.032	-0.4306	Yes
155	ADORA2B	1434430_s_at 1434431_x_at 1434772_at 1450214_at	18689	-1.035	-0.4273	Yes
156	CYBB	1422978_at 1436778_at 1436779_at	18699	-1.038	-0.4241	Yes
157	CCR4	1421655_a_at	18874	-1.109	-0.4282	Yes
158	IRAK2	1436507_at	18879	-1.112	-0.4245	Yes
159	WAS	1419631_at	19033	-1.182	-0.4275	Yes
160	TRAT1	1427532_at 1437561_at	19059	-1.194	-0.4244	Yes
161	RAC1	1423734_at 1437674_at 1451086_s_at	19167	-1.249	-0.4250	Yes
162	ITGB1	1426918_at 1426919_at 1426920_x_at 1427771_x_at 1438119_at 1452545_a_at	19211	-1.269	-0.4226	Yes
163	GPR68	1455000_at	19331	-1.339	-0.4234	Yes
164	NCF1	1425609_at 1451767_at 1456772_at	19352	-1.349	-0.4196	Yes
165	CCR9	1421919_a_at 1421920_a_at 1427419_x_at	19359	-1.351	-0.4151	Yes
166	LY96	1449874_at	19372	-1.362	-0.4109	Yes
167	CD48	1427301_at	19435	-1.398	-0.4089	Yes
168	MLF2	1423916_s_at	19520	-1.461	-0.4076	Yes
169	ZNF148	1418381_at 1427730_a_at 1436217_at 1441612_at 1441701_at 1449068_at 1449069_at 1455483_at	19615	-1.511	-0.4067	Yes
170	ANXA1	1448213_at	19616	-1.511	-0.4014	Yes
171	PTPRCAP	1448511_at	19621	-1.514	-0.3963	Yes
172	CD160	1420066_s_at 1420067_at 1420396_at 1456847_at	19836	-1.670	-0.4003	Yes
173	NFE2L1	1416331_a_at	19894	-1.715	-0.3970	Yes
174	CCR6	1450357_a_at	19905	-1.725	-0.3914	Yes
175	CXCR4	1448710_at	19996	-1.803	-0.3893	Yes
176	PGLYRP2	1420515_a_at	20026	-1.823	-0.3842	Yes
177	HDAC4	1436758_at 1447566_at 1454693_at	20114	-1.896	-0.3816	Yes
178	CD83	1416111_at	20120	-1.898	-0.3752	Yes
179	SOCS6	1435492_at 1450129_a_at 1452764_at 1459350_at	20263	-2.005	-0.3747	Yes
180	RELA	1419536_a_at	20278	-2.013	-0.3684	Yes
181	CD84	1422875_at 1446505_at	20353	-2.059	-0.3646	Yes
182	LY75	1449328_at	20468	-2.172	-0.3622	Yes
183	ALOX15	1420338_at	20542	-2.258	-0.3577	Yes
184	CD97	1418394_a_at	20547	-2.260	-0.3500	Yes
185	NMI	1425719_a_at	20625	-2.363	-0.3453	Yes
186	CCL22	1417925_at	20749	-2.506	-0.3422	Yes
187	NFRKB	1434753_at 1445551_at	20817	-2.610	-0.3362	Yes
188	PARP4	1441026_at	21041	-2.979	-0.3360	Yes
189	TNFRSF1A	1417291_at	21202	-3.374	-0.3316	Yes
190	PRF1	1451862_a_at	21298	-3.633	-0.3233	Yes
191	MPO	1415960_at	21304	-3.651	-0.3108	Yes
192	FOS	1423100_at	21307	-3.658	-0.2981	Yes
193	GATA3	1448886_at	21331	-3.739	-0.2861	Yes
194	VEZF1	1429084_at 1429085_at 1444663_at	21439	-4.122	-0.2766	Yes
195	BCL2	1422938_at 1427818_at 1437122_at 1440770_at 1443837_x_at 1457687_at	21497	-4.358	-0.2640	Yes
196	SPN	1422133_at 1439034_at	21505	-4.387	-0.2490	Yes
197	HDAC5	1415743_at	21541	-4.626	-0.2345	Yes
198	TNIP1	1427689_a_at	21563	-4.786	-0.2187	Yes
199	PGLYRP1	1449184_at	21630	-5.331	-0.2032	Yes
200	HDAC7A	1420812_at 1420813_at	21637	-5.344	-0.1848	Yes
201	NFATC3	1419976_s_at 1452497_a_at	21694	-5.798	-0.1671	Yes
202	CAMP	1419691_at	21706	-5.966	-0.1468	Yes
203	TGFB1	1420653_at 1445360_at	21716	-6.029	-0.1261	Yes
204	BNIP3L	1416922_a_at 1416923_a_at 1448525_a_at	21783	-6.883	-0.1051	Yes
205	LSP1	1417756_a_at	21830	-7.396	-0.0814	Yes
206	S100A9	1448756_at	21916	-8.114	-0.0570	Yes
207	CCR7	1423466_at	21917	-8.151	-0.0285	Yes
208	S100A8	1419394_s_at	21930	-8.411	0.0003	Yes