Details for gene set V$TBP

Table: GSEA Results Summary

Dataset	Set_01_SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls #SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls #SCID_versus_ATM_plus_repos
Phenotype	phenotype_SCID_versus_ATM_plus.cls#SCID_versus_ATM_plus_repos
Upregulated in class	ATM_plus
GeneSet	V$TBP_01
Enrichment Score (ES)	-0.39252427
Normalized Enrichment Score (NES)	-1.5462316
Nominal p-value	0.0032310179
FDR q-value	0.1227073
FWER p-Value	0.823

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PRKAA2	1429463_at 1429464_at	116	5.825	0.0230	No
2	COL1A2	1446326_at 1450857_a_at	678	2.983	0.0117	No
3	RPS19	1449243_a_at 1460442_at	1241	2.174	-0.0035	No
4	CUL3	1422794_at 1422795_at 1434717_at 1434718_at 1450756_s_at	1251	2.168	0.0066	No
5	SFRS3	1416150_a_at 1416151_at 1416152_a_at 1454993_a_at	1255	2.164	0.0170	No
6	NR0B1	1417760_at	1425	2.039	0.0191	No
7	COL10A1	1422253_at	1631	1.935	0.0191	No
8	KCTD15	1435339_at	1802	1.845	0.0203	No
9	FGF21	1422916_at	2035	1.705	0.0179	No
10	LUC7L	1428255_at 1431181_a_at 1431664_at 1452708_a_at	2068	1.688	0.0247	No
11	USH3A	1438347_at	2105	1.668	0.0311	No
12	ABR	1433477_at	2282	1.577	0.0307	No
13	ASB4	1423422_at 1433919_at	2430	1.509	0.0313	No
14	HOXB4	1451761_at 1460379_at	2455	1.499	0.0375	No
15	LGI1	1423183_at 1435851_at	2586	1.441	0.0385	No
16	HIST2H2BE	1447854_s_at 1455095_at	3283	1.236	0.0125	No
17	USP47	1426976_at 1426977_at 1457454_at	3351	1.222	0.0154	No
18	ASB18	1426116_at	3430	1.205	0.0177	No
19	TEF	1424175_at 1438033_at 1450184_s_at	3436	1.204	0.0233	No
20	SH3GLB2	1426499_at	3890	1.115	0.0079	No
21	MYH8	1426650_at	4238	1.055	-0.0029	No
22	HSPB3	1449872_at	4343	1.041	-0.0026	No
23	SLC3A1	1448741_at	4415	1.030	-0.0009	No
24	DMD	1417307_at 1430320_at 1446156_at 1448665_at 1457022_at	4532	1.018	-0.0013	No
25	HDAC9	1421306_a_at 1434572_at	4559	1.014	0.0025	No
26	SYTL2	1421594_a_at 1456593_at	4561	1.014	0.0074	No
27	CLCN1	1427591_at 1448082_at	4703	1.000	0.0058	No
28	MAP2K5	1417854_at 1430180_at 1453712_a_at 1455941_s_at	4822	0.987	0.0051	No
29	HOXC4	1422870_at	4907	0.978	0.0060	No
30	NDST4	1421318_at 1431452_at 1450195_at	4974	0.970	0.0077	No
31	CYP26B1	1460011_at	5070	0.956	0.0080	No
32	FXYD1	1421374_a_at	5323	0.921	0.0009	No
33	GPR23	1434186_at 1439665_at 1452424_at	5458	0.901	-0.0009	No
34	SLC35F5	1452059_at	5481	0.898	0.0025	No
35	AGT	1423396_at	5502	0.895	0.0059	No
36	P2RX5	1449433_at	5670	0.874	0.0025	No
37	ASB16	1452023_at	5838	0.850	-0.0011	No
38	NOG	1422300_at	5857	0.848	0.0022	No
39	ZFP95	1424892_at 1430562_at	5936	0.839	0.0027	No
40	PNMA1	1429224_at	5942	0.838	0.0066	No
41	MGAT3	1422145_at 1428801_at 1428802_at	5984	0.834	0.0088	No
42	FHL2	1419184_a_at	6035	0.828	0.0105	No
43	GRIK4	1437681_at	6113	0.817	0.0109	No
44	PLEC1	1419835_s_at 1434610_at 1437554_at	6119	0.816	0.0147	No
45	THBS2	1422571_at 1447862_x_at 1450663_at	6143	0.812	0.0175	No
46	SOX9	1424950_at 1433889_at 1451538_at	6144	0.812	0.0215	No
47	SEMA4B	1427586_at 1455678_at	6195	0.805	0.0231	No
48	GIT1	1454759_at	6493	0.768	0.0132	No
49	RAB5B	1422119_at 1437446_at	6643	0.751	0.0100	No
50	CLDN23	1424409_at	6946	0.716	-0.0004	No
51	DES	1426731_at	7015	0.709	-0.0001	No
52	DIRAS1	1425748_at 1451820_at 1455526_at	7035	0.707	0.0025	No
53	PPP1R3A	1422108_at	7047	0.705	0.0054	No
54	FGF5	1426186_a_at 1438883_at	7279	0.678	-0.0019	No
55	ACTA1	1427735_a_at	7332	0.671	-0.0010	No
56	TSC1	1422043_at 1439989_at 1455252_at	7601	0.641	-0.0102	No
57	HOXC5	1439885_at 1450832_at 1456301_at	7806	0.620	-0.0166	No
58	BRUNOL4	1426929_at 1426930_at 1452240_at 1458475_at	7858	0.615	-0.0159	No
59	KPNA3	1421828_at 1445527_at 1446538_at 1450385_at 1450386_at	7951	0.605	-0.0172	No
60	TNFRSF17	1420782_at	8049	0.594	-0.0188	No
61	ESRRG	1421747_at 1455267_at 1457896_at	8157	0.584	-0.0209	No
62	CHRDL1	1421295_at 1424945_at 1434201_at 1456722_at	8233	0.577	-0.0215	No
63	SCHIP1	1423025_a_at 1437700_at 1446421_at 1458588_at	8295	0.570	-0.0215	No
64	COL13A1	1422866_at	8526	0.547	-0.0295	No
65	PANK1	1418715_at 1429813_at 1429814_at 1431028_a_at 1457110_at	8725	0.527	-0.0360	No
66	GSC	1421412_at	8813	0.519	-0.0375	No
67	LHX5	1420348_at	8977	0.502	-0.0425	No
68	MYOCD	1425808_a_at 1425978_at	9081	0.491	-0.0449	No
69	DKK4	1425447_at	9464	0.455	-0.0602	No
70	HOXA10	1431475_a_at 1446408_at	9499	0.451	-0.0596	No
71	ITGA7	1418393_a_at	9613	0.439	-0.0626	No
72	PPARGC1A	1434099_at 1434100_x_at 1437751_at 1456395_at 1460336_at	9733	0.427	-0.0660	No
73	LRRTM3	1434759_at 1434760_at 1434761_at 1440112_at 1444477_at	9937	0.408	-0.0734	No
74	ART5	1427759_a_at 1451553_at	9974	0.403	-0.0731	No
75	MAT2A	1423667_at 1433576_at 1438386_x_at 1438630_x_at 1438976_x_at 1439386_x_at 1456702_x_at	9994	0.401	-0.0720	No
76	HOXC6	1427361_at 1427362_x_at 1427454_at	10057	0.396	-0.0729	No
77	RILP	1457696_at	10398	0.365	-0.0868	No
78	MYST2	1433433_at 1440746_at 1447631_at	10457	0.360	-0.0877	No
79	STAC	1418957_at 1445344_at	10458	0.360	-0.0859	No
80	BICD1	1427530_at 1437548_at 1438701_at 1451684_a_at	10584	0.347	-0.0900	No
81	CPA4	1453770_at	10677	0.338	-0.0926	No
82	CTNNAL1	1420929_at 1420930_s_at	10796	0.325	-0.0964	No
83	S100A4	1424542_at	10838	0.322	-0.0967	No
84	RASGRP3	1438030_at 1438031_at	10844	0.321	-0.0954	No
85	TCF1	1421234_at	10910	0.315	-0.0969	No
86	ZCCHC5	1437355_at	11107	0.300	-0.1044	No
87	RIT1	1420540_a_at 1428710_at	11153	0.296	-0.1050	No
88	HRC	1419109_at	11220	0.290	-0.1067	No
89	EN1	1418618_at	11279	0.283	-0.1079	No
90	SOX5	1423500_a_at 1432189_a_at 1432190_at 1440827_x_at 1446461_at 1452511_at 1459261_at	11358	0.274	-0.1102	No
91	IGF1	1419519_at 1436497_at 1437401_at 1452014_a_at	11389	0.271	-0.1103	No
92	PTF1A	1419424_at	11406	0.269	-0.1097	No
93	POFUT1	1443881_at 1450137_at 1456323_at	11414	0.269	-0.1087	No
94	ASB5	1449356_at	11565	0.253	-0.1144	No
95	GPR153	1426973_at	11689	0.240	-0.1188	No
96	DMPK	1422989_a_at 1434944_at	11838	0.224	-0.1246	No
97	TPM2	1419738_a_at 1419739_at 1425028_a_at 1449577_x_at	12071	0.202	-0.1342	No
98	HAND2	1422221_at 1436041_at 1443854_at 1446812_at	12269	0.185	-0.1424	No
99	GPSN2	1416352_s_at 1429681_a_at	12400	0.173	-0.1475	No
100	DNAJA4	1418591_at 1418592_at 1434196_at	12554	0.159	-0.1538	No
101	EHD1	1416010_a_at 1416011_x_at 1416012_at 1448175_at	12642	0.151	-0.1570	No
102	TRDN	1426134_at 1426142_a_at 1426143_at 1426144_x_at 1451801_at 1451940_x_at	12670	0.149	-0.1576	No
103	NR0B2	1449854_at	12761	0.141	-0.1610	No
104	ART3	1441752_at 1452474_a_at	12942	0.122	-0.1687	No
105	HOXB5	1418415_at	12953	0.121	-0.1686	No
106	NME5	1422727_at	13155	0.100	-0.1773	No
107	BNC2	1438861_at 1440593_at 1459132_at	13306	0.081	-0.1838	No
108	MSC	1418417_at	13374	0.073	-0.1865	No
109	GCG	1425952_a_at	13512	0.058	-0.1926	No
110	FZD8	1423348_at 1445815_at	13680	0.041	-0.2000	No
111	POU4F1	1429667_at 1429668_at	13756	0.033	-0.2033	No
112	PAK6	1445475_at 1455200_at	13862	0.021	-0.2080	No
113	TNRC4	1452851_at	14085	-0.001	-0.2182	No
114	HAPLN1	1421633_a_at 1426294_at 1426295_at 1438020_at 1445735_at 1458109_at	14167	-0.012	-0.2219	No
115	ANGPT4	1438364_x_at 1440832_at 1450325_at	14275	-0.025	-0.2267	No
116	ABCC6	1421212_at	14337	-0.031	-0.2294	No
117	CDH20	1450312_at	14349	-0.033	-0.2297	No
118	RHOBTB1	1429206_at 1429656_at	14528	-0.057	-0.2376	No
119	IFNB1	1422305_at	14651	-0.072	-0.2429	No
120	GRIN2B	1422223_at 1431700_at	14788	-0.090	-0.2487	No
121	NANOS1	1436648_at 1455877_a_at	14931	-0.107	-0.2547	No
122	MEOX2	1424233_at 1424234_s_at	15138	-0.135	-0.2635	No
123	TUBA4	1417373_a_at 1417374_at 1417375_at	15151	-0.137	-0.2634	No
124	NTF3	1434802_s_at 1450803_at	15301	-0.159	-0.2694	No
125	TRPM4	1435549_at	15304	-0.159	-0.2688	No
126	CRISP1	1416325_at	15415	-0.177	-0.2730	No
127	PACSIN3	1416995_at 1431534_at 1437834_s_at 1456191_x_at	15525	-0.193	-0.2770	No
128	CFL2	1418066_at 1418067_at 1431432_at	15653	-0.213	-0.2818	No
129	GABRB2	1450319_at	15670	-0.214	-0.2815	No
130	SLC2A4	1415958_at 1415959_at	15946	-0.264	-0.2929	No
131	B3GALT6	1421155_at 1435252_at 1440340_at	16311	-0.331	-0.3080	No
132	ANKRD23	1428183_at	16339	-0.337	-0.3076	No
133	PAX3	1420389_at 1430335_a_at 1441743_at 1459148_at	16556	-0.382	-0.3157	No
134	BRAF	1425693_at 1435434_at 1435480_at 1442749_at 1445786_at 1447940_a_at 1447941_x_at 1456505_at 1458641_at	16748	-0.432	-0.3224	No
135	EPHA7	1427528_a_at 1443485_at 1445635_at 1451991_at 1452380_at	16772	-0.438	-0.3213	No
136	SLC25A4	1424562_a_at 1424563_at 1434897_a_at 1455069_x_at	16947	-0.483	-0.3269	No
137	MEIS1	1440431_at 1443260_at 1445773_at 1450992_a_at 1459423_at 1459512_at	17382	-0.603	-0.3439	No
138	SLC30A1	1422786_at 1436164_at	17487	-0.636	-0.3456	No
139	LBX1	1422323_a_at 1427400_at	17591	-0.672	-0.3471	No
140	SSH3	1447929_at	17643	-0.685	-0.3461	No
141	NCOR1	1423200_at 1423201_at 1423202_a_at 1435914_at 1438276_at 1444760_at 1445230_at 1446574_at 1457007_at 1457938_at 1458103_at	17663	-0.691	-0.3436	No
142	AQP1	1416203_at	18062	-0.833	-0.3579	No
143	PLAGL2	1417517_at 1417518_at 1417519_at 1442235_at	18433	-0.959	-0.3702	No
144	SLC35C2	1420054_s_at 1420055_at 1460731_at	18509	-0.983	-0.3689	No
145	ADAM11	1450248_at	18545	-0.993	-0.3656	No
146	TLK1	1439158_at 1444730_at 1455024_at 1456407_a_at 1460002_at	18572	-1.000	-0.3620	No
147	ELMO1	1424523_at 1446610_at 1450208_a_at	18664	-1.028	-0.3612	No
148	FBXW11	1425461_at 1425462_at 1437468_x_at 1438336_at 1443010_at 1447294_at 1457485_at	18894	-1.117	-0.3662	No
149	DNM2	1423629_at 1425135_a_at 1425136_x_at 1432004_a_at 1432005_at 1437938_x_at 1443150_at 1451057_x_at	18967	-1.156	-0.3639	No
150	TAX1BP3	1424169_at	19005	-1.170	-0.3599	No
151	NNT	1416105_at 1432608_at 1456573_x_at	19316	-1.330	-0.3677	No
152	TTC17	1428862_at	19826	-1.666	-0.3830	No
153	BEX2	1417388_at	20034	-1.828	-0.3836	Yes
154	CSNK1E	1417175_at 1417176_at 1435373_at	20181	-1.956	-0.3808	Yes
155	PRKAG1	1417690_at 1433533_x_at 1457803_at	20271	-2.010	-0.3751	Yes
156	CKB	1455106_a_at	20450	-2.152	-0.3729	Yes
157	ITGB3BP	1420665_at 1442993_at 1449953_at 1456097_a_at	20484	-2.185	-0.3637	Yes
158	SH3BGRL3	1416528_at	20554	-2.267	-0.3559	Yes
159	FLI1	1422024_at 1433512_at 1441584_at	20634	-2.375	-0.3480	Yes
160	CTCF	1418330_at 1449042_at	20645	-2.384	-0.3368	Yes
161	GALNT1	1423236_at 1423237_at	20657	-2.396	-0.3257	Yes
162	CPEB4	1420617_at 1420618_at 1449931_at	20663	-2.401	-0.3142	Yes
163	RARA	1450180_a_at	20670	-2.414	-0.3028	Yes
164	NDRG2	1448154_at	20751	-2.507	-0.2942	Yes
165	RCOR1	1434336_s_at 1437545_at 1454932_at	20828	-2.619	-0.2850	Yes
166	TMEPAI	1422705_at	20834	-2.630	-0.2724	Yes
167	DYRK2	1428637_at 1436918_at 1456502_at 1457667_x_at	20840	-2.640	-0.2598	Yes
168	PPP2R2A	1429715_at 1437730_at 1453260_a_at	21059	-3.027	-0.2551	Yes
169	ACYP2	1427943_at	21088	-3.107	-0.2413	Yes
170	CPNE1	1433439_at	21120	-3.158	-0.2273	Yes
171	ZFP36L1	1422528_a_at 1450644_at	21283	-3.593	-0.2173	Yes
172	FOS	1423100_at	21307	-3.658	-0.2006	Yes
173	AMPD1	1434722_at	21502	-4.384	-0.1882	Yes
174	TUBA1	1418884_x_at	21593	-5.061	-0.1677	Yes
175	PLA2G4B	1425045_at 1456047_at	21603	-5.139	-0.1431	Yes
176	HDAC7A	1420812_at 1420813_at	21637	-5.344	-0.1186	Yes
177	ABLIM1	1442376_at 1453103_at 1454708_at 1460120_at	21696	-5.811	-0.0930	Yes
178	CDC42EP3	1422642_at 1450700_at	21714	-6.013	-0.0645	Yes
179	NR4A1	1416505_at	21809	-7.139	-0.0341	Yes
180	EGR2	1427682_a_at 1427683_at	21921	-8.208	0.0007	Yes