Details for gene set V$HFH1

Table: GSEA Results Summary

Dataset	Set_01_SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls #SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls #SCID_versus_ATM_plus_repos
Phenotype	phenotype_SCID_versus_ATM_plus.cls#SCID_versus_ATM_plus_repos
Upregulated in class	ATM_plus
GeneSet	V$HFH1_01
Enrichment Score (ES)	-0.4017742
Normalized Enrichment Score (NES)	-1.5738755
Nominal p-value	0.0
FDR q-value	0.115487106
FWER p-Value	0.709

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PPP1CB	1426205_at 1431328_at 1433540_x_at 1456462_x_at	287	4.199	0.0059	No
2	EMX2	1456258_at	293	4.147	0.0245	No
3	IMPDH2	1415851_a_at 1415852_at	425	3.642	0.0351	No
4	FOXB1	1420705_at	629	3.117	0.0399	No
5	MRPS18B	1451164_a_at	685	2.970	0.0509	No
6	HESX1	1420604_at	1324	2.113	0.0312	No
7	ATP2A2	1416551_at 1427250_at 1427251_at 1437797_at 1443551_at 1452363_a_at 1458927_at	1602	1.951	0.0273	No
8	BCL11B	1440137_at 1441762_at 1450339_a_at	1772	1.860	0.0280	No
9	HOXB4	1451761_at 1460379_at	2455	1.499	0.0035	No
10	ANKRD28	1434630_at 1454801_at	2458	1.497	0.0102	No
11	FOXD3	1422210_at	2547	1.454	0.0128	No
12	LGI1	1423183_at 1435851_at	2586	1.441	0.0176	No
13	ASPA	1418472_at	2722	1.396	0.0177	No
14	BRIP1	1458427_at	2828	1.360	0.0191	No
15	KCNQ5	1427426_at 1441071_at	3034	1.302	0.0156	No
16	CACNA1D	1427974_s_at 1428051_a_at	3130	1.273	0.0170	No
17	CREB5	1440089_at 1442576_at 1457222_at	3136	1.272	0.0225	No
18	DOCK3	1428852_at 1452930_at	3208	1.252	0.0250	No
19	SLC39A8	1416832_at 1448482_at	3268	1.240	0.0279	No
20	ARHGEF17	1419938_s_at 1419939_at 1433682_at 1442357_at 1447441_at	3749	1.140	0.0110	No
21	SOX14	1427609_at	3783	1.134	0.0147	No
22	PRDM1	1420425_at 1444997_at	4071	1.083	0.0064	No
23	KCNIP4	1437631_at 1450370_a_at 1451840_at	4088	1.079	0.0106	No
24	RNF17	1425708_at 1425709_at 1438820_at 1459275_at	4284	1.048	0.0064	No
25	DNAJC5B	1418725_at	4352	1.040	0.0080	No
26	GPX1	1460671_at	4365	1.037	0.0122	No
27	LMO4	1420981_a_at 1439651_at	4400	1.032	0.0153	No
28	POU2AF1	1416957_at	4524	1.018	0.0143	No
29	DMD	1417307_at 1430320_at 1446156_at 1448665_at 1457022_at	4532	1.018	0.0186	No
30	DPYSL2	1433770_at 1450502_at 1458188_at 1458632_at	4572	1.013	0.0214	No
31	BUB3	1416815_s_at 1448058_s_at 1448473_at 1459104_at 1459918_at	4606	1.010	0.0245	No
32	POU3F4	1422164_at 1422165_at	4627	1.007	0.0282	No
33	MAPK10	1437195_x_at 1448342_at 1458002_at 1458062_at 1458513_at	4773	0.992	0.0260	No
34	MYL1	1452651_a_at	4794	0.990	0.0296	No
35	HOXC4	1422870_at	4907	0.978	0.0289	No
36	NRP1	1418084_at 1448943_at 1448944_at 1457198_at	4920	0.976	0.0328	No
37	CYP26B1	1460011_at	5070	0.956	0.0303	No
38	PPP2R3A	1455198_a_at	5366	0.913	0.0209	No
39	TOB1	1423176_at 1440844_at	5630	0.879	0.0128	No
40	OPA3	1455131_at	5654	0.876	0.0157	No
41	SCG3	1448628_at	5664	0.875	0.0193	No
42	RPS6KB1	1428849_at 1446376_at 1454956_at 1457562_at 1459951_at 1460705_at	5736	0.863	0.0199	No
43	RREB1	1428657_at 1434741_at 1438216_at 1442047_at 1452862_at	5933	0.839	0.0147	No
44	HOXA11	1420414_at	6070	0.824	0.0122	No
45	TBX4	1426321_at 1456033_at	6099	0.819	0.0147	No
46	TRERF1	1444654_at	6284	0.795	0.0098	No
47	SEMA6D	1446536_at 1448060_at 1453055_at 1459318_at	6362	0.785	0.0098	No
48	HR	1422110_at 1435950_at	6863	0.726	-0.0098	No
49	NLGN3	1456384_at	6895	0.722	-0.0080	No
50	ING3	1422805_a_at 1422806_x_at 1450760_a_at 1460082_at	6975	0.714	-0.0084	No
51	SLC12A5	1425337_at 1445933_at 1451674_at	7126	0.696	-0.0121	No
52	EFEMP1	1427183_at	7194	0.689	-0.0120	No
53	VIT	1426231_at	7338	0.670	-0.0156	No
54	HHEX	1423319_at	7542	0.648	-0.0219	No
55	FOXP2	1422014_at 1438231_at 1438232_at 1440108_at 1441365_at 1458191_at	7614	0.640	-0.0223	No
56	C1QTNF6	1431856_a_at	7676	0.633	-0.0222	No
57	PHEX	1421979_at 1450445_at	7993	0.601	-0.0340	No
58	ANGPTL1	1421421_at 1421791_at 1446396_at 1455224_at	8112	0.588	-0.0368	No
59	DNAJB12	1421032_a_at 1435886_at	8212	0.579	-0.0387	No
60	ATP1B4	1422908_at	8533	0.546	-0.0509	No
61	FCHSD2	1434260_at 1456949_at	8690	0.531	-0.0557	No
62	NTN1	1422987_at 1454974_at	8752	0.524	-0.0561	No
63	ATOH1	1449822_at	8760	0.524	-0.0540	No
64	HOXB8	1452493_s_at	8775	0.523	-0.0523	No
65	SATB2	1425904_at 1427017_at	8797	0.521	-0.0509	No
66	CRH	1457984_at	9179	0.481	-0.0662	No
67	NEUROD4	1418054_at 1418055_at 1436694_s_at	9183	0.481	-0.0642	No
68	OTP	1422285_at	9277	0.474	-0.0663	No
69	OMD	1418745_at	9466	0.455	-0.0728	No
70	HOXA10	1431475_a_at 1446408_at	9499	0.451	-0.0723	No
71	HTR1B	1422288_at	9825	0.419	-0.0853	No
72	EFNA5	1421796_a_at 1436866_at 1440052_at 1446383_at 1451930_at	9868	0.416	-0.0853	No
73	PITX2	1424797_a_at 1450482_a_at	9912	0.411	-0.0854	No
74	WNT2	1449425_at	10054	0.396	-0.0901	No
75	HOXC6	1427361_at 1427362_x_at 1427454_at	10057	0.396	-0.0884	No
76	ICK	1448310_at 1454243_at 1455687_at	10141	0.389	-0.0905	No
77	CHD1	1420990_at 1444787_at 1444788_x_at 1450077_at 1457473_at	10504	0.355	-0.1055	No
78	ELAVL2	1421881_a_at 1421882_a_at 1421883_at 1433052_at	10577	0.348	-0.1072	No
79	SALL3	1441186_at 1452386_at	10613	0.344	-0.1073	No
80	VAX1	1421774_at	10791	0.326	-0.1139	No
81	GRB7	1448227_at	11036	0.305	-0.1237	No
82	MSI2	1421230_a_at 1421231_at 1435520_at 1435521_at 1436818_a_at 1441185_at 1441373_at 1443008_at 1443530_at 1446022_at 1458136_at 1458542_at	11105	0.300	-0.1255	No
83	PPP2R2B	1426621_a_at	11190	0.293	-0.1280	No
84	SLC38A2	1426722_at 1429593_at 1429594_at	11476	0.263	-0.1399	No
85	DTNA	1419223_a_at 1425292_at 1426066_a_at 1427588_a_at 1429768_at 1447280_at 1456069_at 1458908_at	11539	0.256	-0.1416	No
86	GTF2A1	1421357_at	11616	0.248	-0.1440	No
87	SLIT3	1427086_at 1452296_at	11920	0.216	-0.1569	No
88	C1QTNF3	1422606_at	12113	0.199	-0.1648	No
89	SOX2	1416967_at	12142	0.197	-0.1652	No
90	ZADH2	1451277_at	12229	0.189	-0.1683	No
91	ARHGEF2	1421042_at 1421043_s_at 1427646_a_at	12518	0.163	-0.1808	No
92	DOCK1	1443390_at 1443760_at 1443991_at 1452220_at 1457806_at	12575	0.157	-0.1827	No
93	CITED2	1417129_a_at 1421267_a_at 1439915_at 1440091_at 1443561_at 1443926_at 1445638_at 1446176_at 1447861_x_at 1457632_s_at 1459301_at	12585	0.156	-0.1824	No
94	OTX1	1437601_at	12687	0.147	-0.1864	No
95	OTX2	1425926_a_at	12906	0.126	-0.1958	No
96	CYLN2	1422984_at	12969	0.120	-0.1981	No
97	LHX9	1419324_at 1431598_a_at 1441313_x_at	12981	0.118	-0.1981	No
98	PDZRN4	1456512_at	13124	0.103	-0.2041	No
99	A2BP1	1418314_a_at 1438217_at 1447735_x_at 1455358_at 1456921_at	13219	0.092	-0.2080	No
100	GRIK2	1425790_a_at 1439286_at 1440602_at 1445090_at 1457683_at	13225	0.091	-0.2079	No
101	GRIK3	1427709_at	13300	0.082	-0.2109	No
102	SNCAIP	1423499_at 1430463_a_at 1441037_at	13329	0.078	-0.2118	No
103	IBSP	1417484_at 1417485_at	13399	0.071	-0.2147	No
104	PROX1	1421336_at 1437894_at 1457432_at	13412	0.070	-0.2149	No
105	FST	1421365_at 1434458_at	13729	0.036	-0.2293	No
106	SLC6A14	1420503_at 1420504_at	13965	0.010	-0.2400	No
107	KLF12	1439846_at 1439847_s_at 1441040_at 1455521_at	13967	0.010	-0.2400	No
108	PMCH	1429361_at	13989	0.008	-0.2410	No
109	INHBA	1422053_at 1458291_at	13990	0.008	-0.2409	No
110	NFIB	1416293_at 1427680_a_at 1434101_at 1434102_at 1438072_at 1438244_at 1442214_at 1444800_at 1448288_at 1454834_at	14282	-0.026	-0.2542	No
111	HHIP	1421426_at 1437933_at 1438083_at 1455277_at	14366	-0.035	-0.2578	No
112	CLDN8	1449091_at	14423	-0.043	-0.2602	No
113	CLN5	1426886_at	14761	-0.087	-0.2753	No
114	MAPK3	1427060_at	14832	-0.095	-0.2781	No
115	MCC	1438081_at 1442741_at 1442892_at 1459524_at 1459752_at	14949	-0.109	-0.2829	No
116	FGF9	1420795_at 1438718_at 1445258_at	15056	-0.126	-0.2872	No
117	TAF5L	1448195_at	15087	-0.129	-0.2880	No
118	NTF3	1434802_s_at 1450803_at	15301	-0.159	-0.2971	No
119	IRS4	1441429_at	15441	-0.181	-0.3026	No
120	EZH1	1418290_a_at 1429629_at 1429630_at 1444604_at 1449023_a_at	15641	-0.210	-0.3108	No
121	ENPEP	1448649_at	15711	-0.220	-0.3130	No
122	NCAM1	1421966_at 1425126_at 1426864_a_at 1426865_a_at 1439556_at 1440067_at 1441995_at 1442680_at 1443018_at 1450437_a_at 1450438_at 1454140_at	16044	-0.280	-0.3270	No
123	AP1G2	1419113_at	16047	-0.281	-0.3258	No
124	PCDH7	1427592_at 1437442_at 1449249_at 1456214_at	16151	-0.300	-0.3292	No
125	FSTL1	1416221_at 1448259_at	16346	-0.338	-0.3366	No
126	EIF4EBP2	1417084_at 1436158_at 1437733_at 1455575_at 1456613_at	16485	-0.366	-0.3412	No
127	NCDN	1416852_a_at 1416853_at	16492	-0.368	-0.3398	No
128	WHSC1L1	1442085_at 1447931_at 1455668_at 1457630_at 1457793_a_at 1457794_at 1459907_a_at	16639	-0.402	-0.3447	No
129	SLITRK6	1437231_at	16736	-0.430	-0.3472	No
130	BCL11A	1419406_a_at 1426552_a_at 1446293_at 1447334_at 1447335_x_at 1453814_at 1456632_at	16815	-0.447	-0.3487	No
131	LCP2	1418641_at 1418642_at	16988	-0.493	-0.3544	No
132	TACSTD2	1423323_at	17111	-0.524	-0.3576	No
133	TRIM8	1418577_at 1427593_at 1438679_at 1460237_at	17139	-0.530	-0.3564	No
134	CASK	1422518_at 1422519_at 1427692_a_at 1445152_at	17210	-0.551	-0.3572	No
135	GOLGA1	1431120_a_at 1432054_at 1435027_at 1446087_at	17773	-0.723	-0.3797	No
136	NIN	1419078_at 1444155_at	17900	-0.771	-0.3820	No
137	PPM1D	1434142_at 1449092_at 1459069_at	17915	-0.774	-0.3791	No
138	SLC16A6	1417884_at	18076	-0.835	-0.3827	No
139	ASB7	1435010_at 1438744_at 1446319_at 1450363_at	18229	-0.890	-0.3856	No
140	ETV5	1420998_at 1428142_at 1450082_s_at	18320	-0.919	-0.3856	No
141	TLK1	1439158_at 1444730_at 1455024_at 1456407_a_at 1460002_at	18572	-1.000	-0.3925	No
142	PHF8	1439132_at 1459392_at 1460398_at	18674	-1.030	-0.3925	No
143	IHPK2	1428373_at 1435319_at	18675	-1.030	-0.3878	No
144	PIK3C2A	1421023_at 1425862_a_at 1443655_s_at	18741	-1.054	-0.3860	No
145	BRMS1L	1452850_s_at 1460443_at	19085	-1.203	-0.3963	Yes
146	RASSF2	1428392_at 1444889_at	19124	-1.229	-0.3925	Yes
147	TBN	1416450_at 1416451_s_at	19223	-1.280	-0.3911	Yes
148	CD2BP2	1417223_at 1417224_a_at 1448624_at	19277	-1.307	-0.3876	Yes
149	RAD21	1416161_at 1416162_at 1455938_x_at	19482	-1.433	-0.3905	Yes
150	ZFYVE1	1435071_at 1435072_at	19572	-1.487	-0.3878	Yes
151	SUMO1	1438289_a_at 1444557_at 1451005_at 1456349_x_at	19865	-1.693	-0.3936	Yes
152	SECISBP2	1428496_at 1428497_at	19914	-1.731	-0.3879	Yes
153	LAMC1	1423885_at 1423886_at	20064	-1.855	-0.3863	Yes
154	TAF10	1448784_at	20133	-1.917	-0.3807	Yes
155	NEO1	1423513_at 1434931_at 1440789_at 1444295_at 1447693_s_at 1447694_x_at 1459485_at	20193	-1.964	-0.3745	Yes
156	PRKAG1	1417690_at 1433533_x_at 1457803_at	20271	-2.010	-0.3689	Yes
157	SSBP3	1425940_a_at 1427917_s_at 1439136_at 1443554_at 1457560_at 1458749_at	20315	-2.037	-0.3616	Yes
158	LAG3	1449911_at	20459	-2.160	-0.3584	Yes
159	ITGB3BP	1420665_at 1442993_at 1449953_at 1456097_a_at	20484	-2.185	-0.3495	Yes
160	PIM1	1423006_at 1435458_at	20778	-2.545	-0.3514	Yes
161	ELF1	1417540_at 1439319_at	20812	-2.600	-0.3411	Yes
162	SERTAD4	1454877_at	20886	-2.716	-0.3321	Yes
163	PPP1R10	1426726_at 1426727_s_at 1430560_at	20899	-2.728	-0.3203	Yes
164	CSNK1G3	1429383_at 1429384_at 1458994_at	21019	-2.943	-0.3123	Yes
165	STAG2	1421849_at 1450396_at	21067	-3.048	-0.3006	Yes
166	CPNE1	1433439_at	21120	-3.158	-0.2887	Yes
167	UBE2H	1418631_at 1418632_at 1428791_at 1438971_x_at 1447374_at 1459930_at	21165	-3.289	-0.2757	Yes
168	KCTD12	1434881_s_at	21374	-3.890	-0.2676	Yes
169	HSD11B1	1449038_at	21430	-4.094	-0.2515	Yes
170	PURA	1420628_at 1438219_at 1449934_at 1453783_at 1456898_at	21442	-4.147	-0.2332	Yes
171	NEDD4	1421955_a_at 1444044_at 1450431_a_at 1451109_a_at	21487	-4.321	-0.2155	Yes
172	CAPN3	1426043_a_at 1433681_x_at	21616	-5.239	-0.1976	Yes
173	DUSP1	1448830_at	21619	-5.241	-0.1739	Yes
174	SMAD1	1416081_at 1448208_at 1459843_s_at	21702	-5.922	-0.1507	Yes
175	SCN4B	1434008_at	21709	-5.982	-0.1238	Yes
176	ISG20	1419569_a_at	21753	-6.425	-0.0965	Yes
177	NR4A1	1416505_at	21809	-7.139	-0.0666	Yes
178	NR4A2	1447863_s_at 1450749_a_at 1450750_a_at 1455034_at	21861	-7.700	-0.0339	Yes
179	EGR2	1427682_a_at 1427683_at	21921	-8.208	0.0007	Yes