Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_01_SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls #SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls #SCID_versus_ATM_plus_repos |
| Phenotype | phenotype_SCID_versus_ATM_plus.cls#SCID_versus_ATM_plus_repos |
| Upregulated in class | SCID |
| GeneSet | KTGGYRSGAA_UNKNOWN |
| Enrichment Score (ES) | 0.46127534 |
| Normalized Enrichment Score (NES) | 1.6038785 |
| Nominal p-value | 0.010638298 |
| FDR q-value | 0.08581242 |
| FWER p-Value | 0.438 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | LUC7L2 | 1423251_at 1427087_at 1436165_at 1436766_at 1436767_at 1437761_at 1458423_at | 40 | 7.725 | 0.0719 | Yes | ||
| 2 | MCM6 | 1416251_at 1438852_x_at 1447756_x_at | 182 | 5.000 | 0.1131 | Yes | ||
| 3 | RFC4 | 1424321_at 1438161_s_at | 234 | 4.560 | 0.1543 | Yes | ||
| 4 | LIG1 | 1416641_at | 239 | 4.526 | 0.1972 | Yes | ||
| 5 | POLD1 | 1448187_at 1456055_x_at | 413 | 3.679 | 0.2244 | Yes | ||
| 6 | RANBP1 | 1422547_at | 490 | 3.453 | 0.2539 | Yes | ||
| 7 | CENPH | 1422016_a_at | 540 | 3.327 | 0.2834 | Yes | ||
| 8 | RCOR2 | 1417302_at | 627 | 3.122 | 0.3092 | Yes | ||
| 9 | TOPBP1 | 1452241_at 1458480_at | 680 | 2.980 | 0.3353 | Yes | ||
| 10 | ORC1L | 1422663_at 1443172_at | 950 | 2.513 | 0.3470 | Yes | ||
| 11 | WEE1 | 1416773_at 1416774_at | 973 | 2.481 | 0.3696 | Yes | ||
| 12 | MCM7 | 1416030_a_at 1416031_s_at 1438320_s_at | 1113 | 2.307 | 0.3853 | Yes | ||
| 13 | MYC | 1424942_a_at | 1314 | 2.118 | 0.3963 | Yes | ||
| 14 | YARS | 1460638_at | 1412 | 2.048 | 0.4114 | Yes | ||
| 15 | SH3BP1 | 1460222_at | 1517 | 1.996 | 0.4257 | Yes | ||
| 16 | TIMM23 | 1416485_at | 1627 | 1.937 | 0.4392 | Yes | ||
| 17 | SEMA5A | 1422167_at 1434776_at 1437422_at 1446772_at 1446865_at 1446910_at 1459109_at | 1639 | 1.933 | 0.4571 | Yes | ||
| 18 | CDCA7 | 1428069_at 1445681_at | 2034 | 1.706 | 0.4554 | Yes | ||
| 19 | IGSF4 | 1417376_a_at 1417377_at 1417378_at 1431611_a_at | 2241 | 1.602 | 0.4613 | Yes | ||
| 20 | SPRED1 | 1423160_at 1423161_s_at 1423162_s_at 1428777_at 1441517_at 1442859_at 1443652_x_at 1445228_at 1452911_at 1460116_s_at | 4318 | 1.043 | 0.3763 | No | ||
| 21 | SFRS7 | 1424033_at 1424883_s_at 1436871_at | 4848 | 0.983 | 0.3616 | No | ||
| 22 | BOLL | 1427599_at 1432529_at 1432530_s_at | 5352 | 0.916 | 0.3473 | No | ||
| 23 | RREB1 | 1428657_at 1434741_at 1438216_at 1442047_at 1452862_at | 5933 | 0.839 | 0.3288 | No | ||
| 24 | HTF9C | 1434244_x_at 1441920_x_at 1448114_a_at 1448115_at 1453995_a_at 1457620_at | 6042 | 0.827 | 0.3318 | No | ||
| 25 | DCLRE1A | 1417904_at 1432097_a_at 1442329_at | 6153 | 0.810 | 0.3345 | No | ||
| 26 | SEC61A1 | 1416189_a_at 1416190_a_at 1416191_at 1434986_a_at 1448242_at 1455987_at | 6613 | 0.755 | 0.3207 | No | ||
| 27 | AP4M1 | 1418846_at | 6908 | 0.721 | 0.3141 | No | ||
| 28 | UHRF1 | 1415810_at 1415811_at 1439227_at | 7900 | 0.610 | 0.2746 | No | ||
| 29 | FLRT1 | 1443143_at | 9012 | 0.499 | 0.2286 | No | ||
| 30 | ZADH2 | 1451277_at | 12229 | 0.189 | 0.0835 | No | ||
| 31 | BCAS3 | 1423528_at 1428454_at 1457817_at 1458557_at | 12800 | 0.138 | 0.0587 | No | ||
| 32 | CNTFR | 1419429_at 1431663_a_at | 13307 | 0.081 | 0.0364 | No | ||
| 33 | RBBP4 | 1434892_x_at 1442443_at 1454791_a_at 1454875_a_at 1456260_at | 13322 | 0.079 | 0.0365 | No | ||
| 34 | SYNCRIP | 1422768_at 1422769_at 1426402_at 1428546_at 1450743_s_at | 14134 | -0.009 | -0.0005 | No | ||
| 35 | DLGAP4 | 1426465_at 1455548_at | 14930 | -0.107 | -0.0358 | No | ||
| 36 | RIN2 | 1426368_at 1441209_at 1442829_at | 15050 | -0.124 | -0.0401 | No | ||
| 37 | SH3KBP1 | 1431592_a_at 1432269_a_at 1446562_at 1456261_at 1460337_at | 15140 | -0.136 | -0.0428 | No | ||
| 38 | TUBA4 | 1417373_a_at 1417374_at 1417375_at | 15151 | -0.137 | -0.0420 | No | ||
| 39 | DMRTB1 | 1427252_at | 15366 | -0.169 | -0.0502 | No | ||
| 40 | KCND2 | 1422834_at 1422835_at 1446065_at 1447764_at 1450773_at 1459288_at | 15580 | -0.201 | -0.0580 | No | ||
| 41 | PRIM1 | 1418369_at 1444544_at 1449061_a_at | 15774 | -0.230 | -0.0646 | No | ||
| 42 | SFRS1 | 1428099_a_at 1428100_at 1430982_at 1434972_x_at 1452430_s_at 1453722_s_at 1457136_at | 16974 | -0.491 | -0.1147 | No | ||
| 43 | NHLRC2 | 1429145_at 1433929_at 1444863_at 1453048_at 1457312_at | 17631 | -0.682 | -0.1382 | No | ||
| 44 | DAXX | 1419026_at | 17806 | -0.738 | -0.1391 | No | ||
| 45 | EZH2 | 1416544_at 1444263_at | 18393 | -0.943 | -0.1569 | No | ||
| 46 | MIS12 | 1424717_at | 19031 | -1.181 | -0.1748 | No | ||
| 47 | BRMS1L | 1452850_s_at 1460443_at | 19085 | -1.203 | -0.1657 | No | ||
| 48 | GNAQ | 1428938_at 1428939_s_at 1428940_at 1429559_at 1446688_at 1447593_x_at 1450115_at 1455729_at 1458159_at | 19888 | -1.709 | -0.1861 | No | ||
| 49 | USP32 | 1430403_at 1436159_at 1439857_at 1440399_at 1443689_at 1459857_at | 19918 | -1.735 | -0.1708 | No | ||
| 50 | DDB2 | 1425706_a_at 1436680_s_at | 20152 | -1.933 | -0.1630 | No | ||
| 51 | PIM1 | 1423006_at 1435458_at | 20778 | -2.545 | -0.1673 | No | ||
| 52 | ZHX2 | 1455210_at | 21272 | -3.557 | -0.1559 | No | ||
| 53 | FYB | 1452117_a_at | 21343 | -3.791 | -0.1230 | No | ||
| 54 | GDI1 | 1447613_at 1451070_at | 21503 | -4.385 | -0.0884 | No | ||
| 55 | TUBA1 | 1418884_x_at | 21593 | -5.061 | -0.0442 | No | ||
| 56 | MCM3 | 1420029_at 1426653_at | 21738 | -6.271 | 0.0090 | No |
