Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_01_SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls #SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls #SCID_versus_ATM_plus_repos |
| Phenotype | phenotype_SCID_versus_ATM_plus.cls#SCID_versus_ATM_plus_repos |
| Upregulated in class | ATM_plus |
| GeneSet | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES |
| Enrichment Score (ES) | -0.6993738 |
| Normalized Enrichment Score (NES) | -1.953364 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.011605187 |
| FWER p-Value | 0.144 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | AKT1 | 1416657_at 1425711_a_at 1440950_at 1442759_at | 1442 | 2.030 | -0.0285 | No | ||
| 2 | PIK3CA | 1423144_at 1429434_at 1429435_x_at 1440054_at 1453134_at 1460326_at | 1705 | 1.898 | -0.0055 | No | ||
| 3 | MAPK1 | 1419568_at 1426585_s_at 1442876_at 1453104_at | 2405 | 1.522 | -0.0093 | No | ||
| 4 | BAD | 1416582_a_at 1416583_at | 4101 | 1.077 | -0.0669 | No | ||
| 5 | JAK3 | 1425750_a_at 1446515_at | 4514 | 1.019 | -0.0669 | No | ||
| 6 | SHC1 | 1422853_at 1422854_at | 6200 | 0.804 | -0.1290 | No | ||
| 7 | IRS1 | 1423104_at | 8672 | 0.532 | -0.2320 | No | ||
| 8 | GSK3A | 1435638_at | 14112 | -0.007 | -0.4801 | No | ||
| 9 | MAPK3 | 1427060_at | 14832 | -0.095 | -0.5112 | No | ||
| 10 | RAF1 | 1416078_s_at 1425419_a_at | 15969 | -0.268 | -0.5581 | No | ||
| 11 | PPP1R13B | 1434895_s_at 1442956_at 1459224_at | 16622 | -0.396 | -0.5805 | No | ||
| 12 | AKT3 | 1422078_at 1435260_at 1435879_at 1443222_at 1460307_at | 17013 | -0.498 | -0.5892 | No | ||
| 13 | SOS1 | 1421884_at 1421885_at 1421886_at | 18257 | -0.899 | -0.6294 | No | ||
| 14 | GRB2 | 1418508_a_at 1449111_a_at | 19792 | -1.642 | -0.6691 | Yes | ||
| 15 | STAT6 | 1421708_a_at 1426353_at | 19854 | -1.685 | -0.6409 | Yes | ||
| 16 | JAK1 | 1433803_at 1433804_at 1433805_at | 20384 | -2.085 | -0.6267 | Yes | ||
| 17 | IL4R | 1421034_a_at 1423996_a_at 1447858_x_at | 20417 | -2.115 | -0.5892 | Yes | ||
| 18 | IRS2 | 1443969_at | 20483 | -2.185 | -0.5520 | Yes | ||
| 19 | PIK3R1 | 1425514_at 1425515_at 1438682_at 1444591_at 1451737_at | 20549 | -2.262 | -0.5133 | Yes | ||
| 20 | SOS2 | 1452281_at | 20571 | -2.283 | -0.4722 | Yes | ||
| 21 | AKT2 | 1421324_a_at 1424480_s_at 1455703_at | 20735 | -2.493 | -0.4338 | Yes | ||
| 22 | PIK3CD | 1422991_at 1422992_s_at 1443798_at 1453281_at 1458321_at | 20915 | -2.748 | -0.3913 | Yes | ||
| 23 | SOCS1 | 1440047_at 1450446_a_at | 21397 | -3.962 | -0.3404 | Yes | ||
| 24 | BCL2 | 1422938_at 1427818_at 1437122_at 1440770_at 1443837_x_at 1457687_at | 21497 | -4.358 | -0.2647 | Yes | ||
| 25 | GSK3B | 1434439_at 1437001_at 1439931_at 1439949_at 1451020_at 1454958_at | 21863 | -7.710 | -0.1394 | Yes | ||
| 26 | PDK1 | 1423747_a_at 1423748_at 1434974_at 1435836_at | 21874 | -7.752 | 0.0028 | Yes |
