Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_01_SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls #SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls #SCID_versus_ATM_plus_repos |
| Phenotype | phenotype_SCID_versus_ATM_plus.cls#SCID_versus_ATM_plus_repos |
| Upregulated in class | SCID |
| GeneSet | DNA_REPLICATION_REACTOME |
| Enrichment Score (ES) | 0.7546353 |
| Normalized Enrichment Score (NES) | 2.36949 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PRIM2A | 1418035_a_at 1418036_at 1445474_at | 23 | 7.946 | 0.0833 | Yes | ||
| 2 | CDT1 | 1424143_a_at 1424144_at 1455791_at | 87 | 6.599 | 0.1504 | Yes | ||
| 3 | CDC6 | 1417019_a_at | 179 | 5.023 | 0.1996 | Yes | ||
| 4 | MCM6 | 1416251_at 1438852_x_at 1447756_x_at | 182 | 5.000 | 0.2525 | Yes | ||
| 5 | GMNN | 1417506_at | 184 | 4.969 | 0.3052 | Yes | ||
| 6 | MCM5 | 1415945_at 1436808_x_at | 216 | 4.655 | 0.3532 | Yes | ||
| 7 | RFC4 | 1424321_at 1438161_s_at | 234 | 4.560 | 0.4008 | Yes | ||
| 8 | RFC5 | 1452917_at | 310 | 4.071 | 0.4406 | Yes | ||
| 9 | RFC3 | 1423700_at 1432538_a_at | 381 | 3.777 | 0.4775 | Yes | ||
| 10 | POLD1 | 1448187_at 1456055_x_at | 413 | 3.679 | 0.5151 | Yes | ||
| 11 | RPA2 | 1416433_at 1454011_a_at | 424 | 3.645 | 0.5533 | Yes | ||
| 12 | NACA | 1416669_s_at | 586 | 3.206 | 0.5800 | Yes | ||
| 13 | MCM2 | 1434079_s_at 1448777_at | 864 | 2.652 | 0.5955 | Yes | ||
| 14 | ORC1L | 1422663_at 1443172_at | 950 | 2.513 | 0.6182 | Yes | ||
| 15 | MCM7 | 1416030_a_at 1416031_s_at 1438320_s_at | 1113 | 2.307 | 0.6353 | Yes | ||
| 16 | POLD2 | 1448277_at | 1137 | 2.275 | 0.6584 | Yes | ||
| 17 | POLA2 | 1425794_at 1448369_at 1456713_at | 1163 | 2.239 | 0.6810 | Yes | ||
| 18 | ORC6L | 1417037_at | 1224 | 2.192 | 0.7016 | Yes | ||
| 19 | POLD3 | 1426838_at 1426839_at 1443733_x_at 1459647_at | 1340 | 2.099 | 0.7186 | Yes | ||
| 20 | MCM10 | 1433407_at 1433408_a_at 1454244_at | 1430 | 2.036 | 0.7361 | Yes | ||
| 21 | POLE | 1441854_at 1448650_a_at | 1491 | 2.004 | 0.7546 | Yes | ||
| 22 | POLE2 | 1427094_at 1431440_at | 4567 | 1.013 | 0.6250 | No | ||
| 23 | RPA1 | 1423293_at 1437309_a_at 1441240_at | 5320 | 0.921 | 0.6004 | No | ||
| 24 | MCM4 | 1416214_at 1436708_x_at | 5554 | 0.888 | 0.5992 | No | ||
| 25 | PCNA | 1417947_at | 6659 | 0.750 | 0.5567 | No | ||
| 26 | CDC45L | 1416575_at 1457838_at | 7163 | 0.692 | 0.5411 | No | ||
| 27 | ORC5L | 1415830_at 1441601_at | 8302 | 0.569 | 0.4952 | No | ||
| 28 | CDC7 | 1426002_a_at 1426021_a_at | 8493 | 0.550 | 0.4923 | No | ||
| 29 | ORC3L | 1416115_at 1416116_at 1416117_at | 10707 | 0.335 | 0.3948 | No | ||
| 30 | CDK2 | 1416873_a_at 1447617_at | 11825 | 0.226 | 0.3462 | No | ||
| 31 | ORC4L | 1423336_at 1423337_at 1431172_at 1453804_a_at | 12855 | 0.131 | 0.3006 | No | ||
| 32 | RPA3 | 1448938_at | 14381 | -0.037 | 0.2314 | No | ||
| 33 | RFC1 | 1418342_at 1449050_at 1451920_a_at | 14675 | -0.076 | 0.2188 | No | ||
| 34 | PRIM1 | 1418369_at 1444544_at 1449061_a_at | 15774 | -0.230 | 0.1711 | No | ||
| 35 | ORC2L | 1418225_at 1418226_at 1418227_at | 18052 | -0.830 | 0.0759 | No | ||
| 36 | UBC | 1420494_x_at 1425965_at 1425966_x_at 1432827_x_at 1437666_x_at 1454373_x_at | 18568 | -0.999 | 0.0630 | No | ||
| 37 | RFC2 | 1417503_at 1457638_x_at 1457669_x_at | 18857 | -1.102 | 0.0615 | No | ||
| 38 | POLD4 | 1427885_at | 19008 | -1.170 | 0.0671 | No | ||
| 39 | MCM3 | 1420029_at 1426653_at | 21738 | -6.271 | 0.0090 | No |
