Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_01_ATM_minus_versus_SCID.phenotype_ATM_minus_versus_SCID.cls #ATM_minus_versus_SCID |
| Phenotype | phenotype_ATM_minus_versus_SCID.cls#ATM_minus_versus_SCID |
| Upregulated in class | SCID |
| GeneSet | PROTEIN_CATABOLIC_PROCESS |
| Enrichment Score (ES) | -0.44689628 |
| Normalized Enrichment Score (NES) | -1.5806224 |
| Nominal p-value | 0.01146789 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | UFD1L | 1418087_at 1432367_a_at | 669 | 2.441 | 0.0091 | No | ||
| 2 | USP33 | 1426709_a_at | 1008 | 1.962 | 0.0255 | No | ||
| 3 | CDC23 | 1433430_s_at 1443087_at 1460549_a_at | 1290 | 1.741 | 0.0410 | No | ||
| 4 | UBE2G1 | 1415688_at 1455094_s_at | 2237 | 1.252 | 0.0181 | No | ||
| 5 | RNF11 | 1426404_a_at 1426405_at 1439685_at 1442048_at 1452058_a_at | 2452 | 1.169 | 0.0273 | No | ||
| 6 | DERL1 | 1415693_at 1423082_at 1433563_s_at 1437723_s_at | 2830 | 1.066 | 0.0274 | No | ||
| 7 | PSMC5 | 1415740_at | 2928 | 1.040 | 0.0399 | No | ||
| 8 | UBE2L3 | 1417907_at 1417908_s_at 1448879_at 1448880_at | 3355 | 0.952 | 0.0359 | No | ||
| 9 | MDM2 | 1423605_a_at 1427718_a_at 1457929_at | 3752 | 0.867 | 0.0319 | No | ||
| 10 | UBE2D3 | 1423112_at 1423113_a_at 1423114_at 1450858_a_at 1450859_s_at 1455479_a_at 1455480_s_at | 3825 | 0.853 | 0.0425 | No | ||
| 11 | FBXL4 | 1456038_at | 4097 | 0.801 | 0.0431 | No | ||
| 12 | CDC20 | 1416664_at 1439377_x_at 1439394_x_at | 4431 | 0.741 | 0.0399 | No | ||
| 13 | NPLOC4 | 1446779_at 1454804_at | 4974 | 0.644 | 0.0256 | No | ||
| 14 | FBXO22 | 1426592_a_at 1426593_a_at 1452121_at | 5103 | 0.623 | 0.0299 | No | ||
| 15 | FBXO7 | 1435310_at 1435311_s_at 1452739_at | 5260 | 0.599 | 0.0325 | No | ||
| 16 | UBE3A | 1416680_at 1416681_at 1416682_at 1425206_a_at 1431224_at 1445727_at | 5573 | 0.555 | 0.0273 | No | ||
| 17 | CPA2 | 1454623_at | 6105 | 0.488 | 0.0109 | No | ||
| 18 | SMURF2 | 1429045_at 1429046_at 1454894_at | 6396 | 0.452 | 0.0050 | No | ||
| 19 | DERL2 | 1435101_at 1448438_at | 7038 | 0.382 | -0.0181 | No | ||
| 20 | UHRF2 | 1447217_at 1454920_at 1457070_at | 7315 | 0.351 | -0.0250 | No | ||
| 21 | PARK2 | 1420755_a_at 1426135_a_at 1449975_a_at | 7732 | 0.311 | -0.0389 | No | ||
| 22 | EGLN2 | 1416533_at | 8203 | 0.266 | -0.0561 | No | ||
| 23 | TSG101 | 1417004_at | 11626 | -0.040 | -0.2118 | No | ||
| 24 | BTRC | 1417325_at 1425680_a_at 1443142_at 1446925_at 1447120_at 1456780_at | 11851 | -0.059 | -0.2211 | No | ||
| 25 | ANAPC10 | 1429375_at 1429376_s_at 1444033_at 1458390_at | 11946 | -0.068 | -0.2243 | No | ||
| 26 | UBE2G2 | 1417032_at 1417033_at | 12583 | -0.124 | -0.2513 | No | ||
| 27 | FAF1 | 1418242_at 1434370_s_at | 13938 | -0.249 | -0.3092 | No | ||
| 28 | UBE4B | 1432499_a_at 1444465_at 1448410_at | 14068 | -0.263 | -0.3108 | No | ||
| 29 | EDEM1 | 1424065_at 1451218_at | 14297 | -0.286 | -0.3166 | No | ||
| 30 | UBE4A | 1425278_at 1425384_a_at 1437747_at 1459708_at | 14787 | -0.340 | -0.3334 | No | ||
| 31 | NEDD8 | 1423715_a_at 1440996_at 1445811_at | 14908 | -0.352 | -0.3332 | No | ||
| 32 | UBE2D1 | 1424062_at | 15095 | -0.373 | -0.3356 | No | ||
| 33 | AMFR | 1450102_a_at | 15633 | -0.434 | -0.3531 | No | ||
| 34 | ANAPC5 | 1416906_at 1433822_x_at 1435177_a_at 1435178_x_at 1453307_a_at 1456695_x_at | 15676 | -0.439 | -0.3479 | No | ||
| 35 | HGS | 1416540_at | 15864 | -0.461 | -0.3489 | No | ||
| 36 | UBE2C | 1452954_at | 16613 | -0.563 | -0.3740 | No | ||
| 37 | SIAH2 | 1448170_at 1448171_at | 16892 | -0.602 | -0.3769 | No | ||
| 38 | STUB1 | 1416580_a_at 1429069_at 1434412_x_at | 17774 | -0.757 | -0.4049 | No | ||
| 39 | SQSTM1 | 1440076_at 1442237_at 1444021_at 1450957_a_at | 17923 | -0.785 | -0.3989 | No | ||
| 40 | MDM4 | 1419558_at 1453982_at 1460542_s_at | 18975 | -1.012 | -0.4305 | Yes | ||
| 41 | PRSS2 | 1417682_a_at 1433459_x_at 1433573_x_at 1435507_x_at | 19036 | -1.022 | -0.4166 | Yes | ||
| 42 | UBE2B | 1423106_at 1423107_at 1430177_at 1439477_at 1460132_at | 19056 | -1.026 | -0.4008 | Yes | ||
| 43 | UBE2D2 | 1416475_at 1416476_a_at 1416477_at 1439655_at 1445885_at 1448356_at | 19318 | -1.083 | -0.3951 | Yes | ||
| 44 | SYVN1 | 1428070_at 1443609_s_at 1446774_at | 19818 | -1.241 | -0.3977 | Yes | ||
| 45 | FZR1 | 1419451_at | 19852 | -1.255 | -0.3788 | Yes | ||
| 46 | UBE2H | 1418631_at 1418632_at 1428791_at 1438971_x_at 1447374_at 1459930_at | 20227 | -1.422 | -0.3728 | Yes | ||
| 47 | FRAP1 | 1417592_at 1436267_a_at 1446185_at 1459625_at | 20253 | -1.435 | -0.3507 | Yes | ||
| 48 | ANAPC4 | 1423930_at 1423931_s_at | 20372 | -1.498 | -0.3317 | Yes | ||
| 49 | SMURF1 | 1443393_at | 21186 | -2.048 | -0.3356 | Yes | ||
| 50 | ARIH1 | 1427188_at 1427189_at 1436498_at 1441022_at 1459397_at 1460090_at | 21233 | -2.091 | -0.3037 | Yes | ||
| 51 | UBE2A | 1417609_at 1448772_at | 21410 | -2.344 | -0.2737 | Yes | ||
| 52 | PCNP | 1428314_at 1452735_at | 21433 | -2.373 | -0.2361 | Yes | ||
| 53 | ANAPC2 | 1415707_at | 21498 | -2.455 | -0.1991 | Yes | ||
| 54 | UBE2I | 1422712_a_at 1422713_a_at 1425478_x_at 1453189_at | 21878 | -5.254 | -0.1311 | Yes | ||
| 55 | PSMD14 | 1421751_a_at 1446521_at 1457765_at 1459734_at | 21932 | -8.226 | 0.0002 | Yes |
