Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_01_ATM_minus_versus_SCID.phenotype_ATM_minus_versus_SCID.cls #ATM_minus_versus_SCID |
| Phenotype | phenotype_ATM_minus_versus_SCID.cls#ATM_minus_versus_SCID |
| Upregulated in class | SCID |
| GeneSet | KINASE_BINDING |
| Enrichment Score (ES) | -0.42223802 |
| Normalized Enrichment Score (NES) | -1.5287726 |
| Nominal p-value | 0.0093240095 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | TPRKB | 1424992_at 1425410_at 1425682_a_at | 663 | 2.453 | 0.0112 | No | ||
| 2 | YWHAG | 1420816_at 1420817_at 1450012_x_at 1459693_x_at | 958 | 2.020 | 0.0319 | No | ||
| 3 | MAP2K7 | 1421416_at 1425393_a_at 1425512_at 1425513_at 1440442_at 1451736_a_at 1457182_at | 1386 | 1.693 | 0.0410 | No | ||
| 4 | LATS1 | 1427679_at 1460264_at | 1710 | 1.501 | 0.0516 | No | ||
| 5 | AKAP11 | 1434764_at | 1862 | 1.427 | 0.0689 | No | ||
| 6 | ADAM9 | 1416094_at | 2075 | 1.321 | 0.0815 | No | ||
| 7 | UBQLN1 | 1419385_a_at 1424368_s_at 1450345_at | 2093 | 1.311 | 0.1029 | No | ||
| 8 | CDKN2A | 1450140_a_at | 2688 | 1.102 | 0.0944 | No | ||
| 9 | AKAP3 | 1421531_at 1456591_x_at | 3027 | 1.018 | 0.0962 | No | ||
| 10 | ADAM10 | 1450104_at 1460083_at | 3870 | 0.844 | 0.0720 | No | ||
| 11 | AKAP12 | 1419706_a_at 1458235_at | 4288 | 0.766 | 0.0659 | No | ||
| 12 | MAPK8IP3 | 1416437_a_at 1425975_a_at 1436676_at 1460628_at | 4327 | 0.761 | 0.0770 | No | ||
| 13 | AVPR1B | 1422204_at | 5145 | 0.616 | 0.0501 | No | ||
| 14 | CD24 | 1416034_at 1437502_x_at 1448182_a_at | 6541 | 0.437 | -0.0063 | No | ||
| 15 | SPDYA | 1429470_at 1432134_at 1441390_at | 7979 | 0.289 | -0.0672 | No | ||
| 16 | LCK | 1425396_a_at 1439145_at 1439146_s_at 1457917_at | 8004 | 0.287 | -0.0634 | No | ||
| 17 | MOBKL1A | 1430564_at 1455184_at | 8033 | 0.284 | -0.0599 | No | ||
| 18 | INSR | 1421380_at 1450225_at | 8247 | 0.262 | -0.0652 | No | ||
| 19 | PICK1 | 1419384_at | 8497 | 0.235 | -0.0726 | No | ||
| 20 | CDK5RAP2 | 1443976_at 1447103_at 1452618_at | 8514 | 0.233 | -0.0694 | No | ||
| 21 | AKAP7 | 1422143_at 1433905_at | 8897 | 0.200 | -0.0835 | No | ||
| 22 | IGF1R | 1426565_at 1437219_at 1443566_at 1445600_at 1445664_at 1446303_at | 9568 | 0.139 | -0.1117 | No | ||
| 23 | GRK5 | 1446361_at 1446998_at 1449514_at | 9571 | 0.139 | -0.1095 | No | ||
| 24 | RB1 | 1417850_at 1441494_at 1444400_at 1444454_at 1457447_at | 10060 | 0.097 | -0.1302 | No | ||
| 25 | IRAK1 | 1448668_a_at 1460649_at | 10167 | 0.089 | -0.1335 | No | ||
| 26 | AKAP5 | 1447301_at | 10302 | 0.077 | -0.1383 | No | ||
| 27 | MAPK8IP2 | 1418785_at 1418786_at 1435045_s_at 1449225_a_at 1455194_at | 10714 | 0.043 | -0.1564 | No | ||
| 28 | MAPK8IP1 | 1425679_a_at 1440619_at | 11065 | 0.011 | -0.1722 | No | ||
| 29 | AVPR1A | 1418603_at 1418604_at | 11156 | 0.003 | -0.1763 | No | ||
| 30 | APC | 1420956_at 1420957_at 1435543_at 1450056_at | 11193 | 0.000 | -0.1779 | No | ||
| 31 | CDKN2C | 1416868_at 1439164_at | 11228 | -0.002 | -0.1794 | No | ||
| 32 | TRIB3 | 1426065_a_at 1456225_x_at | 11356 | -0.015 | -0.1850 | No | ||
| 33 | SIT1 | 1418751_at | 12217 | -0.091 | -0.2228 | No | ||
| 34 | BCAR1 | 1439388_s_at 1450622_at | 12678 | -0.132 | -0.2416 | No | ||
| 35 | PTPRC | 1422124_a_at 1440165_at | 13287 | -0.189 | -0.2662 | No | ||
| 36 | KIF13B | 1433158_at 1433159_at 1436056_at 1453276_at | 13808 | -0.236 | -0.2859 | No | ||
| 37 | FAF1 | 1418242_at 1434370_s_at | 13938 | -0.249 | -0.2876 | No | ||
| 38 | AKAP4 | 1419019_a_at 1431868_at 1451661_at 1451662_x_at | 13965 | -0.252 | -0.2845 | No | ||
| 39 | PTPRR | 1426047_a_at | 14115 | -0.268 | -0.2868 | No | ||
| 40 | ZC3HC1 | 1426654_at | 14152 | -0.272 | -0.2839 | No | ||
| 41 | MAP3K12 | 1417115_at 1438908_at 1456565_s_at | 14452 | -0.301 | -0.2924 | No | ||
| 42 | CDKN2B | 1449152_at | 14572 | -0.314 | -0.2926 | No | ||
| 43 | DLG1 | 1415691_at 1445798_at 1450768_at 1459635_at | 15106 | -0.374 | -0.3106 | No | ||
| 44 | CAMK2N1 | 1456609_at | 17180 | -0.651 | -0.3944 | No | ||
| 45 | TOP2B | 1416731_at 1416732_at 1448458_at 1456688_at | 17652 | -0.731 | -0.4036 | Yes | ||
| 46 | CCND3 | 1415907_at 1437584_at 1444323_at 1446567_at 1447434_at 1457549_at | 17921 | -0.785 | -0.4025 | Yes | ||
| 47 | SQSTM1 | 1440076_at 1442237_at 1444021_at 1450957_a_at | 17923 | -0.785 | -0.3893 | Yes | ||
| 48 | IRS1 | 1423104_at | 18523 | -0.925 | -0.4011 | Yes | ||
| 49 | LLGL1 | 1416621_at | 18709 | -0.967 | -0.3932 | Yes | ||
| 50 | HINT1 | 1424017_a_at 1424018_at 1457286_at | 18873 | -0.997 | -0.3837 | Yes | ||
| 51 | BCL10 | 1418970_a_at 1418971_x_at 1418972_at 1443524_x_at | 19716 | -1.203 | -0.4019 | Yes | ||
| 52 | TOP2A | 1427724_at 1442454_at 1454694_a_at | 19718 | -1.203 | -0.3816 | Yes | ||
| 53 | PRDX3 | 1416292_at | 19765 | -1.219 | -0.3631 | Yes | ||
| 54 | RELA | 1419536_a_at | 19848 | -1.253 | -0.3456 | Yes | ||
| 55 | ITGB2 | 1450678_at | 19948 | -1.288 | -0.3284 | Yes | ||
| 56 | FIZ1 | 1423733_a_at | 20003 | -1.316 | -0.3086 | Yes | ||
| 57 | MAP3K13 | 1430137_at 1440749_at 1447699_at | 20161 | -1.392 | -0.2922 | Yes | ||
| 58 | TRIP6 | 1449041_a_at | 20383 | -1.503 | -0.2769 | Yes | ||
| 59 | LAX1 | 1438687_at | 20539 | -1.588 | -0.2571 | Yes | ||
| 60 | RAD9A | 1418404_at | 20695 | -1.692 | -0.2356 | Yes | ||
| 61 | CDKN2D | 1416253_at | 21221 | -2.083 | -0.2243 | Yes | ||
| 62 | CEP250 | 1421512_at | 21460 | -2.403 | -0.1946 | Yes | ||
| 63 | SOCS1 | 1440047_at 1450446_a_at | 21547 | -2.517 | -0.1559 | Yes | ||
| 64 | RPS6KA4 | 1438243_at 1448498_at | 21550 | -2.522 | -0.1133 | Yes | ||
| 65 | CD4 | 1419696_at 1427779_a_at | 21569 | -2.571 | -0.0707 | Yes | ||
| 66 | PDLIM5 | 1429783_at 1438186_at 1442710_at 1446339_at | 21872 | -5.168 | 0.0029 | Yes |
