Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_01_ATM_minus_versus_SCID.phenotype_ATM_minus_versus_SCID.cls #ATM_minus_versus_SCID |
| Phenotype | phenotype_ATM_minus_versus_SCID.cls#ATM_minus_versus_SCID |
| Upregulated in class | SCID |
| GeneSet | ACTIN_BINDING |
| Enrichment Score (ES) | -0.4281344 |
| Normalized Enrichment Score (NES) | -1.5217198 |
| Nominal p-value | 0.006772009 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | LRPPRC | 1424353_at | 294 | 3.288 | 0.0386 | No | ||
| 2 | TNNI3 | 1422536_at | 570 | 2.668 | 0.0682 | No | ||
| 3 | ANLN | 1433543_at 1439648_at | 1418 | 1.676 | 0.0560 | No | ||
| 4 | ADD2 | 1421975_a_at 1435287_at 1451914_a_at | 1738 | 1.485 | 0.0649 | No | ||
| 5 | SSH2 | 1456153_at | 2498 | 1.155 | 0.0485 | No | ||
| 6 | SVIL | 1427662_at 1460694_s_at 1460735_at | 2913 | 1.043 | 0.0461 | No | ||
| 7 | SYNE1 | 1421545_a_at 1455225_at 1455493_at | 3084 | 1.006 | 0.0542 | No | ||
| 8 | MAP1S | 1454732_at | 3817 | 0.855 | 0.0343 | No | ||
| 9 | TNNT2 | 1418726_a_at 1424967_x_at 1440424_at | 3843 | 0.850 | 0.0466 | No | ||
| 10 | CCR5 | 1422259_a_at 1422260_x_at 1424727_at | 5137 | 0.617 | -0.0028 | No | ||
| 11 | CAPZB | 1417259_a_at 1424168_a_at 1431668_at 1453960_a_at | 5163 | 0.613 | 0.0058 | No | ||
| 12 | MARCKS | 1415971_at 1415972_at 1430311_at 1437034_x_at 1456028_x_at | 5259 | 0.599 | 0.0109 | No | ||
| 13 | ARPC4 | 1423588_at 1423589_at | 5564 | 0.556 | 0.0058 | No | ||
| 14 | CYFIP1 | 1416329_at 1445327_at 1457134_at 1457615_at | 6979 | 0.389 | -0.0527 | No | ||
| 15 | GABARAPL2 | 1423187_at 1441376_at 1444956_at 1459477_at | 8101 | 0.276 | -0.0995 | No | ||
| 16 | UXT | 1418986_a_at | 8224 | 0.264 | -0.1009 | No | ||
| 17 | SCIN | 1450276_a_at | 11967 | -0.069 | -0.2709 | No | ||
| 18 | IQGAP2 | 1433885_at 1459894_at | 12249 | -0.093 | -0.2823 | No | ||
| 19 | ARPC1A | 1416079_a_at | 12302 | -0.098 | -0.2831 | No | ||
| 20 | ABRA | 1458455_at | 12506 | -0.118 | -0.2905 | No | ||
| 21 | SSH1 | 1433874_at 1438253_at 1439237_a_at 1455854_a_at | 12614 | -0.126 | -0.2934 | No | ||
| 22 | LIMA1 | 1422499_at 1425654_a_at 1435726_at 1435727_s_at 1450629_at | 12670 | -0.132 | -0.2938 | No | ||
| 23 | CXCR4 | 1448710_at | 12847 | -0.149 | -0.2995 | No | ||
| 24 | CGN | 1430329_at 1435155_at | 13080 | -0.171 | -0.3074 | No | ||
| 25 | MYO6 | 1421120_at 1433942_at 1435559_at | 13174 | -0.179 | -0.3088 | No | ||
| 26 | COTL1 | 1416001_a_at 1416002_x_at 1425801_x_at 1436236_x_at 1436838_x_at 1437811_x_at | 13355 | -0.196 | -0.3140 | No | ||
| 27 | CALD1 | 1424768_at 1424769_s_at 1424770_at 1433146_at 1433147_at 1458057_at | 13541 | -0.212 | -0.3191 | No | ||
| 28 | ADD1 | 1420953_at 1420954_a_at 1439125_at 1450054_at | 13698 | -0.225 | -0.3226 | No | ||
| 29 | ESPN | 1423005_a_at 1458260_at | 13945 | -0.250 | -0.3299 | No | ||
| 30 | HPCA | 1425833_a_at 1450930_at | 14074 | -0.263 | -0.3316 | No | ||
| 31 | MEFV | 1460283_at | 14476 | -0.304 | -0.3451 | No | ||
| 32 | NRAP | 1421253_at | 14481 | -0.305 | -0.3405 | No | ||
| 33 | MYH10 | 1441057_at 1452740_at | 14739 | -0.333 | -0.3470 | No | ||
| 34 | GC | 1426547_at | 15411 | -0.407 | -0.3712 | No | ||
| 35 | SHROOM3 | 1422629_s_at 1432377_x_at 1442952_at 1445401_at 1451854_a_at 1453714_a_at 1454211_a_at | 16124 | -0.495 | -0.3959 | No | ||
| 36 | FLNA | 1426677_at | 16411 | -0.532 | -0.4006 | No | ||
| 37 | ABLIM1 | 1442376_at 1453103_at 1454708_at 1460120_at | 16416 | -0.533 | -0.3923 | No | ||
| 38 | SPTBN4 | 1425116_a_at | 16669 | -0.573 | -0.3948 | No | ||
| 39 | KPTN | 1423438_at 1440025_at | 16837 | -0.596 | -0.3930 | No | ||
| 40 | MYO9B | 1418031_at 1438533_at 1459110_at | 17055 | -0.629 | -0.3930 | No | ||
| 41 | CNN2 | 1450981_at | 17663 | -0.733 | -0.4091 | No | ||
| 42 | PARVG | 1416875_at 1416876_at | 18008 | -0.801 | -0.4122 | No | ||
| 43 | SYNPO | 1427045_at 1434089_at | 18358 | -0.887 | -0.4141 | Yes | ||
| 44 | NEXN | 1435649_at 1446084_at | 18392 | -0.897 | -0.4014 | Yes | ||
| 45 | DST | 1421117_at 1421276_a_at 1423626_at 1442395_at 1446943_at 1450119_at 1458075_at 1459098_at 1459356_at | 18573 | -0.938 | -0.3948 | Yes | ||
| 46 | MTSS1 | 1424826_s_at 1434036_at 1440847_at 1443729_at 1446284_at 1451496_at | 18827 | -0.989 | -0.3907 | Yes | ||
| 47 | IPP | 1421771_a_at | 18906 | -1.002 | -0.3785 | Yes | ||
| 48 | DMD | 1417307_at 1430320_at 1446156_at 1448665_at 1457022_at | 19004 | -1.017 | -0.3668 | Yes | ||
| 49 | NCALD | 1417568_at 1417569_at 1439730_at 1444466_at 1458037_at | 19350 | -1.094 | -0.3653 | Yes | ||
| 50 | EGFR | 1424932_at 1432647_at 1435888_at 1451530_at 1454313_at 1457563_at 1460420_a_at | 19516 | -1.141 | -0.3548 | Yes | ||
| 51 | WASF2 | 1438683_at | 19578 | -1.156 | -0.3393 | Yes | ||
| 52 | SORBS1 | 1417358_s_at 1425826_a_at 1428471_at 1436737_a_at 1440311_at 1442401_at 1443983_at 1455967_at | 20007 | -1.320 | -0.3380 | Yes | ||
| 53 | DBNL | 1460334_at | 20258 | -1.438 | -0.3266 | Yes | ||
| 54 | LSP1 | 1417756_a_at | 20291 | -1.457 | -0.3050 | Yes | ||
| 55 | CAPZA1 | 1439455_x_at 1440380_at | 20744 | -1.719 | -0.2985 | Yes | ||
| 56 | FXYD5 | 1418296_at | 21361 | -2.252 | -0.2911 | Yes | ||
| 57 | ACTN4 | 1423449_a_at 1444258_at | 21404 | -2.336 | -0.2560 | Yes | ||
| 58 | MYH9 | 1417472_at 1420170_at 1420171_s_at 1420172_at 1440708_at | 21598 | -2.642 | -0.2231 | Yes | ||
| 59 | SMTN | 1452469_a_at | 21860 | -4.679 | -0.1610 | Yes | ||
| 60 | PDLIM5 | 1429783_at 1438186_at 1442710_at 1446339_at | 21872 | -5.168 | -0.0797 | Yes | ||
| 61 | VCL | 1416156_at 1416157_at 1445256_at | 21875 | -5.223 | 0.0028 | Yes |
