Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_01_ATM_minus_versus_SCID.phenotype_ATM_minus_versus_SCID.cls #ATM_minus_versus_SCID |
| Phenotype | phenotype_ATM_minus_versus_SCID.cls#ATM_minus_versus_SCID |
| Upregulated in class | SCID |
| GeneSet | NETPATH_IL4 |
| Enrichment Score (ES) | -0.4425357 |
| Normalized Enrichment Score (NES) | -1.4867696 |
| Nominal p-value | 0.025641026 |
| FDR q-value | 0.79378885 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PIK3R1 | 1425514_at 1425515_at 1438682_at 1444591_at 1451737_at | 749 | 2.311 | 0.0193 | No | ||
| 2 | JAK1 | 1433803_at 1433804_at 1433805_at | 1528 | 1.618 | 0.0212 | No | ||
| 3 | CREBBP | 1434633_at 1435224_at 1436983_at 1444856_at 1457641_at 1459804_at | 1650 | 1.535 | 0.0512 | No | ||
| 4 | EP300 | 1434765_at | 1726 | 1.492 | 0.0823 | No | ||
| 5 | GRB2 | 1418508_a_at 1449111_a_at | 3035 | 1.016 | 0.0460 | No | ||
| 6 | PRKCI | 1417410_s_at 1448695_at | 3767 | 0.864 | 0.0327 | No | ||
| 7 | IL2RG | 1416295_a_at 1416296_at | 4281 | 0.767 | 0.0270 | No | ||
| 8 | PIK3R2 | 1418463_at | 4858 | 0.665 | 0.0161 | No | ||
| 9 | IL4R | 1421034_a_at 1423996_a_at 1447858_x_at | 5796 | 0.527 | -0.0145 | No | ||
| 10 | FES | 1427368_x_at 1452410_a_at | 5969 | 0.505 | -0.0107 | No | ||
| 11 | ELK1 | 1421896_at 1421897_at 1446390_at | 6157 | 0.482 | -0.0081 | No | ||
| 12 | CD40 | 1439221_s_at 1449473_s_at 1460415_a_at | 7289 | 0.355 | -0.0515 | No | ||
| 13 | SRC | 1423240_at 1450918_s_at | 7628 | 0.320 | -0.0596 | No | ||
| 14 | SOCS3 | 1416576_at 1455899_x_at 1456212_x_at | 8417 | 0.243 | -0.0900 | No | ||
| 15 | SOS1 | 1421884_at 1421885_at 1421886_at | 11447 | -0.024 | -0.2278 | No | ||
| 16 | PRKD3 | 1420567_at 1428229_at 1428230_at 1444691_at | 11897 | -0.063 | -0.2468 | No | ||
| 17 | ETS1 | 1422027_a_at 1422028_a_at 1426725_s_at 1452163_at | 12075 | -0.079 | -0.2531 | No | ||
| 18 | RASA1 | 1426476_at 1426477_at 1426478_at 1438998_at | 12131 | -0.084 | -0.2537 | No | ||
| 19 | STAT1 | 1420915_at 1440481_at 1450033_a_at 1450034_at | 12475 | -0.115 | -0.2667 | No | ||
| 20 | SOCS5 | 1423349_at 1423350_at 1441640_at 1442890_at | 12706 | -0.135 | -0.2741 | No | ||
| 21 | CXCR4 | 1448710_at | 12847 | -0.149 | -0.2770 | No | ||
| 22 | PRKCZ | 1418085_at 1449692_at 1454902_at | 14802 | -0.341 | -0.3584 | No | ||
| 23 | BAD | 1416582_a_at 1416583_at | 15828 | -0.457 | -0.3946 | No | ||
| 24 | PTPN6 | 1456694_x_at 1460188_at | 16359 | -0.525 | -0.4067 | No | ||
| 25 | IRS2 | 1443969_at | 16791 | -0.589 | -0.4127 | No | ||
| 26 | BCL2L1 | 1420887_a_at 1420888_at 1426050_at 1426191_a_at | 16991 | -0.619 | -0.4075 | No | ||
| 27 | IL4 | 1449864_at | 17712 | -0.740 | -0.4233 | Yes | ||
| 28 | JAK2 | 1421065_at 1421066_at | 17816 | -0.764 | -0.4103 | Yes | ||
| 29 | IRS1 | 1423104_at | 18523 | -0.925 | -0.4211 | Yes | ||
| 30 | DOK2 | 1416333_at | 18551 | -0.934 | -0.4007 | Yes | ||
| 31 | ADRBK2 | 1434450_s_at 1439178_at 1440801_s_at | 18576 | -0.939 | -0.3801 | Yes | ||
| 32 | PIK3CA | 1423144_at 1429434_at 1429435_x_at 1440054_at 1453134_at 1460326_at | 18657 | -0.956 | -0.3616 | Yes | ||
| 33 | PTK2 | 1423059_at 1430827_a_at 1439198_at 1440082_at 1441475_at 1443384_at 1445137_at | 18966 | -1.010 | -0.3523 | Yes | ||
| 34 | JAK3 | 1425750_a_at 1446515_at | 18967 | -1.010 | -0.3290 | Yes | ||
| 35 | PTPN11 | 1421196_at 1427699_a_at 1451225_at | 18980 | -1.013 | -0.3061 | Yes | ||
| 36 | STAT6 | 1421708_a_at 1426353_at | 19532 | -1.144 | -0.3048 | Yes | ||
| 37 | PLCG1 | 1435149_at 1450360_at | 19559 | -1.152 | -0.2793 | Yes | ||
| 38 | MAPK14 | 1416703_at 1416704_at 1426104_at 1442364_at 1451927_a_at 1459617_at | 19565 | -1.153 | -0.2528 | Yes | ||
| 39 | RELA | 1419536_a_at | 19848 | -1.253 | -0.2367 | Yes | ||
| 40 | SHC1 | 1422853_at 1422854_at | 20047 | -1.343 | -0.2147 | Yes | ||
| 41 | ATF2 | 1426582_at 1426583_at 1427559_a_at 1437777_at 1452116_s_at 1459237_at | 20366 | -1.492 | -0.1947 | Yes | ||
| 42 | NFKB1 | 1427705_a_at 1442949_at | 21385 | -2.296 | -0.1881 | Yes | ||
| 43 | SOCS1 | 1440047_at 1450446_a_at | 21547 | -2.517 | -0.1372 | Yes | ||
| 44 | PRKCD | 1422847_a_at 1442256_at | 21900 | -6.694 | 0.0016 | Yes |
