Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_01_ATM_minus_versus_SCID.phenotype_ATM_minus_versus_SCID.cls #ATM_minus_versus_SCID |
| Phenotype | phenotype_ATM_minus_versus_SCID.cls#ATM_minus_versus_SCID |
| Upregulated in class | SCID |
| GeneSet | CELLMAP_ALPHA6BETA4INTEGRIN |
| Enrichment Score (ES) | -0.4911214 |
| Normalized Enrichment Score (NES) | -1.6656308 |
| Nominal p-value | 0.0024096386 |
| FDR q-value | 0.5146301 |
| FWER p-Value | 0.987 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | RAC1 | 1423734_at 1437674_at 1451086_s_at | 932 | 2.048 | -0.0058 | No | ||
| 2 | MST1R | 1420461_at | 1293 | 1.740 | 0.0089 | No | ||
| 3 | YWHAQ | 1420828_s_at 1420829_a_at 1420830_x_at 1432842_s_at 1437608_x_at 1454378_at 1460590_s_at 1460621_x_at | 1495 | 1.636 | 0.0291 | No | ||
| 4 | DSP | 1427610_at 1435493_at 1435494_s_at | 2324 | 1.216 | 0.0131 | No | ||
| 5 | SMAD2 | 1420634_a_at 1458304_at | 2837 | 1.064 | 0.0088 | No | ||
| 6 | GRB2 | 1418508_a_at 1449111_a_at | 3035 | 1.016 | 0.0180 | No | ||
| 7 | YWHAB | 1420878_a_at 1420879_a_at 1420880_a_at 1436783_x_at 1438708_x_at 1455815_a_at | 3470 | 0.928 | 0.0148 | No | ||
| 8 | SFN | 1448612_at | 4146 | 0.793 | -0.0018 | No | ||
| 9 | ABL1 | 1423999_at 1441291_at 1444134_at 1445153_at | 4519 | 0.722 | -0.0058 | No | ||
| 10 | AR | 1422982_at 1437064_at 1446340_at 1455647_at | 4687 | 0.691 | -0.0010 | No | ||
| 11 | YWHAZ | 1416102_at 1416103_at 1436971_x_at 1436981_a_at 1439005_x_at 1443893_at 1448218_s_at 1448219_a_at | 4787 | 0.676 | 0.0066 | No | ||
| 12 | PIK3R2 | 1418463_at | 4858 | 0.665 | 0.0153 | No | ||
| 13 | RHOA | 1437628_s_at | 5201 | 0.607 | 0.0106 | No | ||
| 14 | MMP7 | 1449478_at | 5961 | 0.506 | -0.0150 | No | ||
| 15 | EIF4EBP1 | 1417562_at 1417563_at 1434976_x_at | 7217 | 0.361 | -0.0659 | No | ||
| 16 | CLCA2 | 1419463_at | 7538 | 0.328 | -0.0746 | No | ||
| 17 | SRC | 1423240_at 1450918_s_at | 7628 | 0.320 | -0.0730 | No | ||
| 18 | YES1 | 1418470_at 1449090_a_at 1456843_at 1458878_at | 8233 | 0.263 | -0.0958 | No | ||
| 19 | FYN | 1417558_at 1441647_at 1448765_at | 8898 | 0.199 | -0.1226 | No | ||
| 20 | VIM | 1438118_x_at 1450641_at 1456292_a_at | 9057 | 0.185 | -0.1265 | No | ||
| 21 | PRKCA | 1427562_a_at 1443069_at 1445028_at 1445395_at 1446598_at 1450945_at | 10066 | 0.097 | -0.1708 | No | ||
| 22 | ITGB4 | 1427387_a_at | 10284 | 0.079 | -0.1793 | No | ||
| 23 | RPSA | 1416196_at 1448245_at | 13047 | -0.169 | -0.3025 | No | ||
| 24 | CLCA1 | 1417852_x_at 1417853_at | 13769 | -0.232 | -0.3313 | No | ||
| 25 | COL17A1 | 1418799_a_at | 14113 | -0.268 | -0.3421 | No | ||
| 26 | ERBB2 | 1424919_at | 15413 | -0.407 | -0.3942 | No | ||
| 27 | MET | 1422990_at | 15671 | -0.439 | -0.3980 | No | ||
| 28 | BAD | 1416582_a_at 1416583_at | 15828 | -0.457 | -0.3970 | No | ||
| 29 | YWHAH | 1416004_at | 16143 | -0.498 | -0.4024 | No | ||
| 30 | PIK3CG | 1422707_at 1422708_at | 17635 | -0.728 | -0.4575 | No | ||
| 31 | PLEC1 | 1419835_s_at 1434610_at 1437554_at | 18373 | -0.891 | -0.4751 | Yes | ||
| 32 | AKT1 | 1416657_at 1425711_a_at 1440950_at 1442759_at | 18494 | -0.919 | -0.4641 | Yes | ||
| 33 | DST | 1421117_at 1421276_a_at 1423626_at 1442395_at 1446943_at 1450119_at 1458075_at 1459098_at 1459356_at | 18573 | -0.938 | -0.4509 | Yes | ||
| 34 | PIK3R3 | 1445097_at 1447068_at 1456482_at | 18625 | -0.950 | -0.4362 | Yes | ||
| 35 | PIK3CA | 1423144_at 1429434_at 1429435_x_at 1440054_at 1453134_at 1460326_at | 18657 | -0.956 | -0.4204 | Yes | ||
| 36 | PTK2 | 1423059_at 1430827_a_at 1439198_at 1440082_at 1441475_at 1443384_at 1445137_at | 18966 | -1.010 | -0.4164 | Yes | ||
| 37 | EGFR | 1424932_at 1432647_at 1435888_at 1451530_at 1454313_at 1457563_at 1460420_a_at | 19516 | -1.141 | -0.4210 | Yes | ||
| 38 | CD151 | 1420921_at 1424093_x_at 1427525_at 1437670_x_at 1440507_at 1451232_at 1456085_x_at | 19607 | -1.166 | -0.4042 | Yes | ||
| 39 | CASP3 | 1426165_a_at 1430192_at 1449839_at | 19993 | -1.310 | -0.3983 | Yes | ||
| 40 | SHC1 | 1422853_at 1422854_at | 20047 | -1.343 | -0.3766 | Yes | ||
| 41 | SMAD3 | 1450471_at 1450472_s_at 1454960_at | 20219 | -1.415 | -0.3590 | Yes | ||
| 42 | FRAP1 | 1417592_at 1436267_a_at 1446185_at 1459625_at | 20253 | -1.435 | -0.3348 | Yes | ||
| 43 | EIF4E | 1450909_at 1457489_at 1459371_at | 20266 | -1.444 | -0.3095 | Yes | ||
| 44 | PIK3CB | 1445731_at 1453069_at | 20292 | -1.458 | -0.2844 | Yes | ||
| 45 | PAK1 | 1420979_at 1420980_at 1450070_s_at 1459029_at | 20746 | -1.720 | -0.2743 | Yes | ||
| 46 | ITGA6 | 1422444_at 1422445_at | 20747 | -1.720 | -0.2434 | Yes | ||
| 47 | YWHAE | 1426384_a_at 1426385_x_at 1435702_s_at 1438839_a_at 1440841_at 1457173_at | 21199 | -2.056 | -0.2272 | Yes | ||
| 48 | PRKCD | 1422847_a_at 1442256_at | 21900 | -6.694 | -0.1390 | Yes | ||
| 49 | MBP | 1419646_a_at 1425263_a_at 1425264_s_at 1433532_a_at 1436201_x_at 1451961_a_at 1454651_x_at 1456228_x_at | 21921 | -7.840 | 0.0007 | Yes |
