Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_01_ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus_repos |
| Phenotype | phenotype_ATM_minus_versus_ATM_plus.cls#ATM_minus_versus_ATM_plus_repos |
| Upregulated in class | ATM_plus |
| GeneSet | HSA04660_T_CELL_RECEPTOR_SIGNALING_PATHWAY |
| Enrichment Score (ES) | -0.524683 |
| Normalized Enrichment Score (NES) | -1.915571 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.03656362 |
| FWER p-Value | 0.228 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PLCG1 | 1435149_at 1450360_at | 8 | 9.555 | 0.0505 | No | ||
| 2 | FYN | 1417558_at 1441647_at 1448765_at | 519 | 4.286 | 0.0499 | No | ||
| 3 | CDK4 | 1422441_x_at | 544 | 4.192 | 0.0712 | No | ||
| 4 | PIK3R2 | 1418463_at | 929 | 3.296 | 0.0711 | No | ||
| 5 | HRAS | 1422407_s_at 1424132_at | 938 | 3.277 | 0.0882 | No | ||
| 6 | MALT1 | 1445068_at 1456126_at 1456429_at | 1490 | 2.604 | 0.0768 | No | ||
| 7 | NCK2 | 1416796_at 1416797_at 1458432_at | 1962 | 2.174 | 0.0668 | No | ||
| 8 | PPP3CC | 1420743_a_at 1430025_at | 2782 | 1.725 | 0.0385 | No | ||
| 9 | PPP3R2 | 1437535_at | 3031 | 1.631 | 0.0358 | No | ||
| 10 | CDC42 | 1415724_a_at 1435807_at 1449574_a_at 1460708_s_at | 3187 | 1.571 | 0.0371 | No | ||
| 11 | MAP3K14 | 1422999_at 1434364_at | 3434 | 1.499 | 0.0338 | No | ||
| 12 | IL10 | 1450330_at | 3873 | 1.363 | 0.0210 | No | ||
| 13 | PDCD1 | 1449835_at | 4467 | 1.236 | 0.0005 | No | ||
| 14 | PTPRC | 1422124_a_at 1440165_at | 4964 | 1.140 | -0.0162 | No | ||
| 15 | IFNG | 1425947_at | 5363 | 1.070 | -0.0287 | No | ||
| 16 | NFKBIE | 1431843_a_at 1458299_s_at | 5438 | 1.058 | -0.0265 | No | ||
| 17 | AKT1 | 1416657_at 1425711_a_at 1440950_at 1442759_at | 5518 | 1.047 | -0.0245 | No | ||
| 18 | KRAS | 1426228_at 1426229_s_at 1434000_at 1451979_at | 5870 | 1.002 | -0.0352 | No | ||
| 19 | CBLC | 1422666_at 1431692_a_at | 7289 | 0.801 | -0.0959 | No | ||
| 20 | NFATC4 | 1423380_s_at 1432821_at 1454369_a_at | 9808 | 0.492 | -0.2085 | No | ||
| 21 | PIK3R3 | 1445097_at 1447068_at 1456482_at | 10072 | 0.461 | -0.2181 | No | ||
| 22 | NFKBIB | 1421266_s_at 1446718_at | 10476 | 0.420 | -0.2343 | No | ||
| 23 | IL4 | 1449864_at | 10496 | 0.418 | -0.2330 | No | ||
| 24 | PPP3R1 | 1421786_at 1433591_at 1450368_a_at | 11141 | 0.347 | -0.2606 | No | ||
| 25 | CSF2 | 1427429_at | 11147 | 0.346 | -0.2590 | No | ||
| 26 | CD3E | 1422105_at 1445748_at | 11363 | 0.321 | -0.2671 | No | ||
| 27 | ZAP70 | 1422701_at 1439749_at 1440178_x_at | 11479 | 0.306 | -0.2708 | No | ||
| 28 | TNF | 1419607_at | 11771 | 0.274 | -0.2826 | No | ||
| 29 | JUN | 1417409_at 1448694_at | 13265 | 0.110 | -0.3504 | No | ||
| 30 | PAK7 | 1440981_at 1446159_at 1455847_at 1458766_at | 13313 | 0.104 | -0.3520 | No | ||
| 31 | CBL | 1434829_at 1446608_at 1450457_at 1455886_at | 13354 | 0.098 | -0.3533 | No | ||
| 32 | PAK3 | 1417923_at 1417924_at 1437318_at | 14191 | -0.013 | -0.3915 | No | ||
| 33 | PIK3CA | 1423144_at 1429434_at 1429435_x_at 1440054_at 1453134_at 1460326_at | 14972 | -0.133 | -0.4265 | No | ||
| 34 | PIK3R1 | 1425514_at 1425515_at 1438682_at 1444591_at 1451737_at | 15248 | -0.177 | -0.4381 | No | ||
| 35 | PAK4 | 1428548_at | 15397 | -0.202 | -0.4438 | No | ||
| 36 | PIK3CB | 1445731_at 1453069_at | 15590 | -0.237 | -0.4514 | No | ||
| 37 | LAT | 1460651_at | 16017 | -0.327 | -0.4691 | No | ||
| 38 | CD40LG | 1422283_at | 16403 | -0.421 | -0.4845 | No | ||
| 39 | NFATC1 | 1417621_at 1425761_a_at 1428479_at 1447084_at 1447085_s_at | 16786 | -0.526 | -0.4992 | No | ||
| 40 | IKBKB | 1426207_at 1426333_a_at 1432275_at 1445141_at 1454184_a_at | 17210 | -0.664 | -0.5150 | No | ||
| 41 | RHOA | 1437628_s_at | 17319 | -0.701 | -0.5162 | No | ||
| 42 | GRB2 | 1418508_a_at 1449111_a_at | 17468 | -0.764 | -0.5189 | Yes | ||
| 43 | AKT3 | 1422078_at 1435260_at 1435879_at 1443222_at 1460307_at | 17472 | -0.767 | -0.5150 | Yes | ||
| 44 | LCP2 | 1418641_at 1418642_at | 17507 | -0.779 | -0.5124 | Yes | ||
| 45 | PAK6 | 1445475_at 1455200_at | 17701 | -0.859 | -0.5167 | Yes | ||
| 46 | CHUK | 1417091_at 1428210_s_at 1451383_a_at | 17804 | -0.903 | -0.5165 | Yes | ||
| 47 | NCK1 | 1421487_a_at 1424543_at 1447271_at | 17872 | -0.934 | -0.5146 | Yes | ||
| 48 | VAV3 | 1417122_at 1417123_at 1446795_at 1448600_s_at 1458630_at | 17899 | -0.949 | -0.5108 | Yes | ||
| 49 | PPP3CA | 1426401_at 1438478_a_at 1440051_at 1452056_s_at 1458495_at | 17912 | -0.953 | -0.5062 | Yes | ||
| 50 | NFKBIA | 1420088_at 1420089_at 1438157_s_at 1448306_at 1449731_s_at | 18087 | -1.008 | -0.5088 | Yes | ||
| 51 | PIK3CG | 1422707_at 1422708_at | 18434 | -1.136 | -0.5186 | Yes | ||
| 52 | CD8B | 1426170_a_at 1446372_at 1448569_at 1458652_at | 18464 | -1.154 | -0.5138 | Yes | ||
| 53 | NFKB2 | 1425902_a_at 1429128_x_at | 18571 | -1.202 | -0.5123 | Yes | ||
| 54 | ITK | 1417171_at 1430833_at 1452518_a_at 1456836_at 1457120_at | 18604 | -1.214 | -0.5073 | Yes | ||
| 55 | MAP3K8 | 1419208_at | 18698 | -1.260 | -0.5048 | Yes | ||
| 56 | SOS1 | 1421884_at 1421885_at 1421886_at | 18731 | -1.279 | -0.4995 | Yes | ||
| 57 | RASGRP1 | 1421176_at 1431749_a_at 1434295_at 1450143_at | 19048 | -1.462 | -0.5062 | Yes | ||
| 58 | LCK | 1425396_a_at 1439145_at 1439146_s_at 1457917_at | 19071 | -1.481 | -0.4993 | Yes | ||
| 59 | SOS2 | 1452281_at | 19166 | -1.543 | -0.4954 | Yes | ||
| 60 | CARD11 | 1430257_at 1435996_at | 19280 | -1.617 | -0.4920 | Yes | ||
| 61 | IL5 | 1425546_a_at 1442049_at 1450550_at | 19394 | -1.700 | -0.4881 | Yes | ||
| 62 | NRAS | 1422688_a_at 1454060_a_at | 19506 | -1.778 | -0.4837 | Yes | ||
| 63 | CD28 | 1417597_at 1437025_at 1443703_at | 19532 | -1.812 | -0.4752 | Yes | ||
| 64 | NFATC2 | 1425901_at 1425990_a_at 1426031_a_at 1426032_at 1439205_at 1440426_at | 19581 | -1.851 | -0.4676 | Yes | ||
| 65 | IKBKG | 1421208_at 1421209_s_at 1435646_at 1435647_at 1450161_at 1454690_at | 19699 | -1.951 | -0.4625 | Yes | ||
| 66 | PAK1 | 1420979_at 1420980_at 1450070_s_at 1459029_at | 19738 | -1.986 | -0.4537 | Yes | ||
| 67 | BCL10 | 1418970_a_at 1418971_x_at 1418972_at 1443524_x_at | 19756 | -1.997 | -0.4439 | Yes | ||
| 68 | CBLB | 1437304_at 1455082_at 1458469_at | 19947 | -2.123 | -0.4413 | Yes | ||
| 69 | CD4 | 1419696_at 1427779_a_at | 20116 | -2.283 | -0.4368 | Yes | ||
| 70 | NFAT5 | 1426029_a_at 1438999_a_at 1439328_at 1439805_at 1448966_a_at 1451921_a_at 1458213_at | 20219 | -2.391 | -0.4287 | Yes | ||
| 71 | CTLA4 | 1419334_at | 20241 | -2.409 | -0.4169 | Yes | ||
| 72 | PDK1 | 1423747_a_at 1423748_at 1434974_at 1435836_at | 20244 | -2.412 | -0.4041 | Yes | ||
| 73 | NFKB1 | 1427705_a_at 1442949_at | 20346 | -2.528 | -0.3953 | Yes | ||
| 74 | CD3D | 1422828_at | 20479 | -2.698 | -0.3870 | Yes | ||
| 75 | GRAP2 | 1456432_at | 20676 | -2.983 | -0.3801 | Yes | ||
| 76 | CD8A | 1440164_x_at 1440811_x_at | 20679 | -2.990 | -0.3643 | Yes | ||
| 77 | PTPN6 | 1456694_x_at 1460188_at | 20681 | -2.991 | -0.3484 | Yes | ||
| 78 | PAK2 | 1434250_at 1454887_at | 20929 | -3.442 | -0.3414 | Yes | ||
| 79 | FOS | 1423100_at | 20955 | -3.496 | -0.3239 | Yes | ||
| 80 | PPP3CB | 1427468_at 1428473_at 1428474_at 1433835_at 1446149_at 1459378_at | 20987 | -3.561 | -0.3064 | Yes | ||
| 81 | ICOS | 1421930_at 1421931_at 1436598_at | 21091 | -3.768 | -0.2910 | Yes | ||
| 82 | VAV1 | 1422932_a_at | 21119 | -3.839 | -0.2719 | Yes | ||
| 83 | CD3G | 1419178_at | 21259 | -4.191 | -0.2559 | Yes | ||
| 84 | PRKCQ | 1426044_a_at | 21404 | -4.723 | -0.2374 | Yes | ||
| 85 | PIK3CD | 1422991_at 1422992_s_at 1443798_at 1453281_at 1458321_at | 21476 | -5.037 | -0.2138 | Yes | ||
| 86 | PIK3R5 | 1434980_at | 21633 | -6.020 | -0.1889 | Yes | ||
| 87 | NFATC3 | 1419976_s_at 1452497_a_at | 21671 | -6.290 | -0.1571 | Yes | ||
| 88 | CD247 | 1420716_at 1426079_at 1426396_at 1428059_at 1428060_at 1438392_at 1452539_a_at | 21823 | -7.633 | -0.1234 | Yes | ||
| 89 | AKT2 | 1421324_a_at 1424480_s_at 1455703_at | 21877 | -7.894 | -0.0838 | Yes | ||
| 90 | VAV2 | 1421272_at 1435065_x_at 1435244_at 1458758_at | 21902 | -8.090 | -0.0419 | Yes | ||
| 91 | TEC | 1441524_at 1460204_at | 21906 | -8.156 | 0.0014 | Yes |
