Table: Gene sets enriched in phenotype ATM_plus (3 samples) [plain text format]

	GS follow link to MSigDB	GS DETAILS	SIZE	ES	NES	NOM p-val	FDR q-val	FWER p-val	RANK AT MAX	LEADING EDGE
1	NCI_DOWNSTREAM SIGNALING IN NAÔVE CD8+ T CELLS	Details ...	49	-0.65	-2.13	0.000	0.005	0.005	2665	tags=39%, list=12%, signal=44%
2	NCI_SIGNALING EVENTS MEDIATED BY STEM CELL FACTOR RECEPTOR (C-KIT)	Details ...	44	-0.66	-2.11	0.000	0.002	0.005	1262	tags=25%, list=6%, signal=26%
3	NETPATH_TCR	Details ...	109	-0.56	-2.07	0.000	0.004	0.010	3334	tags=49%, list=15%, signal=57%
4	NCI_ROLE OF CALCINEURIN-DEPENDENT NFAT SIGNALING IN LYMPHOCYTES	Details ...	80	-0.58	-2.07	0.000	0.003	0.012	2558	tags=33%, list=12%, signal=37%
5	BIOCARTA_MULTI-STEP REGULATION OF TRANSCRIPTION BY PITX2	Details ...	23	-0.73	-2.06	0.000	0.003	0.014	2449	tags=52%, list=11%, signal=59%
6	NCI_TCR SIGNALING IN NAÔVE CD8+ T CELLS	Details ...	108	-0.53	-1.98	0.000	0.009	0.053	2890	tags=37%, list=13%, signal=42%
7	NETPATH_IL4	Details ...	44	-0.60	-1.93	0.000	0.020	0.130	2036	tags=39%, list=9%, signal=43%
8	REACTOME_DOWNSTREAM_TCR_SIGNALING	Details ...	20	-0.72	-1.92	0.002	0.020	0.145	4134	tags=65%, list=19%, signal=80%
9	BIOCARTA_KERATINOCYTE DIFFERENTIATION	Details ...	50	-0.59	-1.90	0.000	0.021	0.170	4844	tags=54%, list=22%, signal=69%
10	BIOCARTA_TRANSCRIPTION REGULATION BY METHYLTRANSFERASE OF CARM1	Details ...	13	-0.79	-1.89	0.000	0.024	0.216	1236	tags=54%, list=6%, signal=57%
11	NCI_TNF RECEPTOR SIGNALING PATHWAY	Details ...	247	-0.45	-1.88	0.000	0.024	0.226	3512	tags=35%, list=16%, signal=41%
12	NCI_IL1-MEDIATED SIGNALING EVENTS	Details ...	187	-0.47	-1.88	0.000	0.022	0.227	2867	tags=29%, list=13%, signal=33%
13	REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES	Details ...	13	-0.76	-1.87	0.000	0.023	0.254	2862	tags=46%, list=13%, signal=53%
14	NCI_TCR SIGNALING IN NAÔVE CD4+ T CELLS	Details ...	118	-0.50	-1.87	0.000	0.023	0.272	3367	tags=38%, list=15%, signal=45%
15	BIOCARTA_CELL TO CELL ADHESION SIGNALING	Details ...	12	-0.78	-1.86	0.000	0.025	0.316	400	tags=25%, list=2%, signal=25%
16	NCI_INSULIN-MEDIATED GLUCOSE TRANSPORT	Details ...	24	-0.65	-1.84	0.002	0.030	0.385	2206	tags=33%, list=10%, signal=37%
17	NCI_CLASS I PI3K SIGNALING EVENTS	Details ...	217	-0.45	-1.83	0.000	0.030	0.400	2911	tags=28%, list=13%, signal=32%
18	NCI_CALCINEURIN-REGULATED NFAT-DEPENDENT TRANSCRIPTION IN LYMPHOCYTES	Details ...	43	-0.56	-1.83	0.000	0.028	0.404	2544	tags=33%, list=12%, signal=37%
19	NETPATH_BCR	Details ...	121	-0.48	-1.83	0.000	0.031	0.447	3369	tags=36%, list=15%, signal=43%
20	NCI_REGULATION OF P38-ALPHA AND P38-BETA	Details ...	144	-0.47	-1.81	0.000	0.035	0.516	2867	tags=30%, list=13%, signal=34%
21	NCI_ENDOTHELINS		151	-0.46	-1.78	0.000	0.047	0.636	2882	tags=25%, list=13%, signal=29%
22	NCI_PLASMA MEMBRANE ESTROGEN RECEPTOR SIGNALING		278	-0.42	-1.77	0.000	0.049	0.668	4360	tags=37%, list=20%, signal=45%
23	REACTOME_PI3K_AKT_SIGNALLING		13	-0.74	-1.77	0.004	0.049	0.687	1670	tags=38%, list=8%, signal=42%
24	NCI_P38 MAPK SIGNALING PATHWAY		164	-0.45	-1.76	0.000	0.051	0.712	3563	tags=34%, list=16%, signal=40%
25	NCI_IFN-GAMMA PATHWAY		334	-0.41	-1.76	0.000	0.052	0.726	3007	tags=27%, list=14%, signal=31%
26	BIOCARTA_PTEN DEPENDENT CELL CYCLE ARREST AND APOPTOSIS		14	-0.71	-1.75	0.002	0.052	0.741	4844	tags=57%, list=22%, signal=73%
27	NCI_TRAIL SIGNALING PATHWAY		276	-0.42	-1.75	0.000	0.052	0.755	2978	tags=28%, list=14%, signal=32%
28	INOH_POSITIVE REGULATION OF (TRANSCRIPTION OF SOCS BY STAT DIMER) IN JAK STAT PATHWAY		132	-0.45	-1.74	0.000	0.056	0.795	2867	tags=25%, list=13%, signal=29%
29	NCI_FOXO FAMILY SIGNALING		43	-0.54	-1.74	0.004	0.057	0.808	4915	tags=51%, list=22%, signal=66%
30	NETPATH_IL2		58	-0.52	-1.73	0.002	0.061	0.838	3699	tags=45%, list=17%, signal=54%
31	REACTOME_TCR_SIGNALING		33	-0.57	-1.72	0.006	0.063	0.860	4134	tags=61%, list=19%, signal=75%
32	NCI_IL12-MEDIATED SIGNALING EVENTS		101	-0.47	-1.72	0.000	0.066	0.879	2672	tags=32%, list=12%, signal=36%
33	INOH_B CELL RECEPTOR SIGNALING PATHWAY		71	-0.49	-1.71	0.000	0.070	0.903	3297	tags=34%, list=15%, signal=40%
34	NCI_CLASS I PI3K SIGNALING EVENTS MEDIATED BY AKT		84	-0.48	-1.71	0.004	0.070	0.906	2871	tags=29%, list=13%, signal=33%
35	NCI_GLYPICAN 1 NETWORK		384	-0.39	-1.69	0.000	0.082	0.942	2911	tags=25%, list=13%, signal=29%
36	NCI_BMP RECEPTOR SIGNALING		197	-0.42	-1.69	0.000	0.081	0.945	2867	tags=27%, list=13%, signal=31%
37	NCI_HIV-1 NEF: NEGATIVE EFFECTOR OF FAS AND TNF-ALPHA		34	-0.55	-1.68	0.012	0.083	0.955	2150	tags=38%, list=10%, signal=42%
38	NETPATH_EPO		37	-0.54	-1.68	0.004	0.081	0.955	2046	tags=32%, list=9%, signal=36%
39	NCI_IL2-MEDIATED SIGNALING EVENTS		108	-0.45	-1.68	0.002	0.082	0.963	4879	tags=48%, list=22%, signal=62%
40	NCI_IL2 SIGNALING EVENTS MEDIATED BY STAT5		27	-0.59	-1.67	0.010	0.082	0.968	4879	tags=63%, list=22%, signal=81%
41	BIOCARTA_HIV-1 NEF: NEGATIVE EFFECTOR OF FAS AND TNF		51	-0.52	-1.67	0.008	0.082	0.973	1792	tags=33%, list=8%, signal=36%
42	BIOCARTA_THE 41BB-DEPENDENT IMMUNE RESPONSE		11	-0.72	-1.67	0.008	0.080	0.973	2013	tags=45%, list=9%, signal=50%
43	REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL		24	-0.59	-1.67	0.012	0.082	0.977	1493	tags=29%, list=7%, signal=31%
44	NCI_GLYPICAN PATHWAY		419	-0.38	-1.66	0.000	0.081	0.979	2911	tags=25%, list=13%, signal=28%
45	REACTOME_PLC_BETA_MEDIATED_EVENTS		10	-0.71	-1.66	0.020	0.082	0.981	4712	tags=70%, list=21%, signal=89%
46	BIOCARTA_ROLE OF NICOTINIC ACETYLCHOLINE RECEPTORS IN THE REGULATION OF APOPTOSIS		15	-0.66	-1.66	0.009	0.082	0.983	2003	tags=33%, list=9%, signal=37%
47	BIOCARTA_INACTIVATION OF GSK3 BY AKT CAUSES ACCUMULATION OF B-CATENIN IN ALVEOLAR MACROPHAGES		37	-0.52	-1.64	0.006	0.093	0.990	2449	tags=30%, list=11%, signal=33%
48	NCI_CASPASE CASCADE IN APOPTOSIS		45	-0.51	-1.64	0.014	0.098	0.994	2150	tags=38%, list=10%, signal=42%
49	NETPATH_IFN-ALPHA		44	-0.51	-1.63	0.004	0.101	0.995	2867	tags=39%, list=13%, signal=44%
50	NCI_TGF-BETA RECEPTOR SIGNALING		262	-0.39	-1.63	0.000	0.099	0.996	3563	tags=29%, list=16%, signal=35%
51	NCI_ATYPICAL NF-KAPPAB PATHWAY		14	-0.67	-1.63	0.010	0.099	0.996	5303	tags=64%, list=24%, signal=85%
52	NCI_AURORA A SIGNALING		60	-0.48	-1.63	0.002	0.098	0.996	2239	tags=28%, list=10%, signal=31%
53	NCI_REGULATION OF CYTOPLASMIC AND NUCLEAR SMAD2/3 SIGNALING		262	-0.39	-1.63	0.000	0.097	0.996	3563	tags=29%, list=16%, signal=35%
54	CELLMAP_NOTCH		48	-0.49	-1.62	0.004	0.099	0.996	4308	tags=42%, list=20%, signal=52%
55	NCI_BCR SIGNALING PATHWAY		63	-0.47	-1.62	0.004	0.099	0.996	2658	tags=27%, list=12%, signal=31%
56	NCI_IL27-MEDIATED SIGNALING EVENTS		24	-0.58	-1.61	0.017	0.102	0.998	3699	tags=42%, list=17%, signal=50%
57	BIOCARTA_CASPASE CASCADE IN APOPTOSIS		21	-0.59	-1.61	0.012	0.104	0.999	2150	tags=48%, list=10%, signal=53%
58	NCI_JNK SIGNALING IN THE CD4+ TCR PATHWAY		32	-0.53	-1.61	0.016	0.103	0.999	1434	tags=22%, list=7%, signal=23%
59	INOH_BETA CATENIN DEGRADATION SIGNALING (CANONICAL)		24	-0.56	-1.61	0.016	0.102	0.999	2645	tags=38%, list=12%, signal=43%
60	NCI_REGULATION OF NUCLEAR SMAD2/3 SIGNALING		262	-0.39	-1.61	0.000	0.102	0.999	3563	tags=29%, list=16%, signal=35%
61	NCI_CANONICAL NF-KAPPAB PATHWAY		34	-0.54	-1.61	0.012	0.100	0.999	4728	tags=50%, list=22%, signal=64%
62	NCI_IL23-MEDIATED SIGNALING EVENTS		60	-0.48	-1.60	0.004	0.103	1.000	4728	tags=40%, list=22%, signal=51%
63	REACTOME_OPIOID_SIGNALLING		23	-0.57	-1.59	0.014	0.107	1.000	858	tags=17%, list=4%, signal=18%
64	BIOCARTA_NF-KB SIGNALING PATHWAY		21	-0.59	-1.59	0.010	0.108	1.000	4233	tags=48%, list=19%, signal=59%
65	NCI_LPA RECEPTOR MEDIATED EVENTS		92	-0.43	-1.58	0.010	0.113	1.000	4728	tags=41%, list=22%, signal=52%
66	NCI_A4B1 AND A4B7 INTEGRIN SIGNALING		25	-0.56	-1.58	0.020	0.112	1.000	2117	tags=20%, list=10%, signal=22%
67	INOH_ERK CASCADE		14	-0.65	-1.58	0.019	0.113	1.000	2558	tags=36%, list=12%, signal=40%
68	REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING		17	-0.59	-1.58	0.036	0.114	1.000	4898	tags=65%, list=22%, signal=83%
69	NETPATH_IL5		32	-0.52	-1.57	0.024	0.114	1.000	4703	tags=53%, list=21%, signal=68%
70	REACTOME_G_PROTEIN_MEDIATED_EVENTS		12	-0.67	-1.57	0.032	0.113	1.000	4712	tags=67%, list=21%, signal=85%
71	NCI_IGF1 PATHWAY		132	-0.41	-1.57	0.002	0.113	1.000	2331	tags=20%, list=11%, signal=22%
72	NETPATH_THROMBOPOIETIN		40	-0.50	-1.57	0.009	0.114	1.000	3297	tags=33%, list=15%, signal=38%
73	BIOCARTA_CALCIUM SIGNALING BY HBX OF HEPATITIS B VIRUS		15	-0.63	-1.56	0.024	0.117	1.000	5003	tags=73%, list=23%, signal=95%
74	INOH_PHOSPHOLIPASE C GAMMA SIGNALING		49	-0.47	-1.56	0.019	0.121	1.000	2890	tags=33%, list=13%, signal=38%
75	BIOCARTA_RAS-INDEPENDENT PATHWAY IN NK CELL-MEDIATED CYTOTOXICITY		19	-0.58	-1.56	0.024	0.120	1.000	2558	tags=32%, list=12%, signal=36%
76	INOH_IKK-NF-KAPPAB CASCADE		12	-0.67	-1.56	0.041	0.119	1.000	2464	tags=42%, list=11%, signal=47%
77	INOH_B-RAF ACTIVATION SIGNALING		29	-0.54	-1.55	0.026	0.122	1.000	4366	tags=48%, list=20%, signal=60%
78	INOH_SIGNALING WITHOUT WNT (MAMMAL)		25	-0.55	-1.55	0.023	0.123	1.000	2645	tags=36%, list=12%, signal=41%
79	NCI_PAXILLIN-DEPENDENT EVENTS MEDIATED BY A4B1		18	-0.59	-1.55	0.030	0.122	1.000	2117	tags=22%, list=10%, signal=25%
80	INOH_SIGNALING WITHOUT WNT (CANONICAL)		29	-0.53	-1.55	0.029	0.121	1.000	2645	tags=34%, list=12%, signal=39%
81	INOH_BETA CATENIN DEGRADATION SIGNALING (MAMMAL)		20	-0.59	-1.55	0.037	0.122	1.000	2645	tags=40%, list=12%, signal=45%
82	REACTOME_DOWNSTREAM_EVENTS_IN_GPCR_SIGNALING		21	-0.56	-1.54	0.031	0.126	1.000	4619	tags=52%, list=21%, signal=66%
83	NCI_RETINOIC ACID RECEPTORS-MEDIATED SIGNALING		38	-0.50	-1.54	0.025	0.125	1.000	1770	tags=24%, list=8%, signal=26%
84	INOH_T CELL RECEPTOR SIGNALING PATHWAY		52	-0.47	-1.54	0.010	0.128	1.000	4208	tags=46%, list=19%, signal=57%
85	BIOCARTA_NFKB ACTIVATION BY NONTYPEABLE HEMOPHILUS INFLUENZAE		28	-0.52	-1.53	0.031	0.127	1.000	2468	tags=29%, list=11%, signal=32%
86	NCI_ANDROGEN-MEDIATED SIGNALING		105	-0.41	-1.53	0.004	0.127	1.000	4712	tags=36%, list=21%, signal=46%
87	BIOCARTA_HUMAN CYTOMEGALOVIRUS AND MAP KINASE PATHWAYS		16	-0.61	-1.53	0.039	0.126	1.000	5003	tags=50%, list=23%, signal=65%
88	BIOCARTA_REGULATION OF TRANSCRIPTIONAL ACTIVITY BY PML		11	-0.68	-1.53	0.055	0.126	1.000	3369	tags=45%, list=15%, signal=54%
89	NCI_REGULATION OF ANDROGEN RECEPTOR ACTIVITY		84	-0.42	-1.53	0.015	0.125	1.000	4535	tags=37%, list=21%, signal=46%
90	BIOCARTA_CONTROL OF SKELETAL MYOGENESIS BY HDAC AND CALCIUM/CALMODULIN-DEPENDENT KINASE (CAMK)		19	-0.57	-1.52	0.038	0.130	1.000	2733	tags=32%, list=12%, signal=36%
91	BIOCARTA_ACTIVATION OF CSK BY CAMP-DEPENDENT PROTEIN KINASE INHIBITS SIGNALING THROUGH THE T CELL RECEPTOR		36	-0.50	-1.51	0.030	0.138	1.000	1843	tags=25%, list=8%, signal=27%
92	BIOCARTA_CHAPERONES MODULATE INTERFERON SIGNALING PATHWAY		17	-0.58	-1.51	0.053	0.143	1.000	4135	tags=53%, list=19%, signal=65%
93	NCI_IL4-MEDIATED SIGNALING EVENTS		57	-0.45	-1.51	0.022	0.143	1.000	2672	tags=32%, list=12%, signal=36%
94	BIOCARTA_BONE REMODELING		15	-0.60	-1.51	0.053	0.142	1.000	5392	tags=60%, list=25%, signal=79%
95	BIOCARTA_TNF/STRESS RELATED SIGNALING		23	-0.54	-1.51	0.029	0.141	1.000	4728	tags=52%, list=22%, signal=66%
96	INOH_RAP1 ACTIVATION SIGNALING (THROUGH CAMP AND EPAC)		25	-0.53	-1.50	0.048	0.146	1.000	4366	tags=52%, list=20%, signal=65%
97	NCI_IL2 SIGNALING EVENTS MEDIATED BY PI3K		62	-0.44	-1.50	0.026	0.145	1.000	4728	tags=47%, list=22%, signal=59%
98	NCI_EPO SIGNALING PATHWAY		31	-0.50	-1.49	0.038	0.148	1.000	3207	tags=39%, list=15%, signal=45%
99	BIOCARTA_SEGMENTATION CLOCK		20	-0.55	-1.48	0.041	0.157	1.000	2898	tags=35%, list=13%, signal=40%
100	BIOCARTA_INHIBITION OF CELLULAR PROLIFERATION BY GLEEVEC		22	-0.54	-1.48	0.069	0.159	1.000	3207	tags=41%, list=15%, signal=48%
101	BIOCARTA_REGULATION OF BAD PHOSPHORYLATION		21	-0.55	-1.48	0.059	0.158	1.000	1912	tags=29%, list=9%, signal=31%
102	BIOCARTA_CTCF: FIRST MULTIVALENT NUCLEAR FACTOR		22	-0.53	-1.48	0.060	0.162	1.000	2672	tags=41%, list=12%, signal=47%
103	NETPATH_IL3		63	-0.43	-1.47	0.019	0.163	1.000	5226	tags=49%, list=24%, signal=64%
104	BIOCARTA_REGULATION OF PGC-1A		18	-0.55	-1.47	0.061	0.164	1.000	4127	tags=61%, list=19%, signal=75%
105	REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY		24	-0.52	-1.47	0.054	0.163	1.000	3240	tags=54%, list=15%, signal=63%
106	INOH_PKA ACTIVATION SIGNALING		49	-0.45	-1.47	0.029	0.164	1.000	1041	tags=14%, list=5%, signal=15%
107	NCI_FAS SIGNALING PATHWAY (CD95)		32	-0.49	-1.47	0.037	0.163	1.000	2150	tags=28%, list=10%, signal=31%
108	INOH_CYTOSOLIC CALCIUM ION CONCENTRATION ELEVATION (THROUGH IP3 RECEPTOR)		15	-0.59	-1.47	0.075	0.162	1.000	2558	tags=33%, list=12%, signal=38%
109	BIOCARTA_IL-7 SIGNAL TRANSDUCTION		15	-0.59	-1.46	0.070	0.164	1.000	3699	tags=60%, list=17%, signal=72%
110	BIOCARTA_TNFR2 SIGNALING PATHWAY		12	-0.62	-1.46	0.089	0.165	1.000	2660	tags=50%, list=12%, signal=57%
111	BIOCARTA_CYCLINS AND CELL CYCLE REGULATION		21	-0.53	-1.45	0.063	0.174	1.000	256	tags=19%, list=1%, signal=19%
112	BIOCARTA_WNT SIGNALING PATHWAY		27	-0.50	-1.45	0.046	0.174	1.000	2854	tags=33%, list=13%, signal=38%
113	REACTOME_CELL_JUNCTION_ORGANIZATION		25	-0.52	-1.45	0.035	0.173	1.000	2367	tags=24%, list=11%, signal=27%
114	NCI_HEDGEHOG SIGNALING EVENTS MEDIATED BY GLI PROTEINS		47	-0.44	-1.45	0.042	0.174	1.000	4741	tags=47%, list=22%, signal=60%
115	BIOCARTA_SIGNAL TRANSDUCTION THROUGH IL1R		35	-0.47	-1.45	0.060	0.174	1.000	4728	tags=37%, list=22%, signal=47%
116	INOH_IL-1_SIGNALING(THROUGH_IKK-NFKB_CASCADE)(CANONICAL)		23	-0.52	-1.45	0.065	0.172	1.000	4728	tags=43%, list=22%, signal=55%
117	REACTOME_SIGNALLING_BY_NGF		64	-0.41	-1.42	0.043	0.196	1.000	4728	tags=42%, list=22%, signal=54%
118	BIOCARTA_CERAMIDE SIGNALING PATHWAY		49	-0.44	-1.42	0.033	0.196	1.000	3494	tags=37%, list=16%, signal=44%
119	BIOCARTA_AKT SIGNALING PATHWAY		14	-0.58	-1.42	0.077	0.195	1.000	1912	tags=36%, list=9%, signal=39%
120	NETPATH_IL6		60	-0.42	-1.42	0.025	0.195	1.000	4221	tags=35%, list=19%, signal=43%
121	CELLMAP_TNF ALPHA/NF-KB		156	-0.36	-1.42	0.013	0.196	1.000	2660	tags=25%, list=12%, signal=28%
122	REACTOME_APOPTOTIC_EXECUTION__PHASE		31	-0.47	-1.41	0.051	0.201	1.000	2150	tags=29%, list=10%, signal=32%
123	REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS		25	-0.50	-1.41	0.062	0.202	1.000	1148	tags=24%, list=5%, signal=25%
124	BIOCARTA_REPRESSION OF PAIN SENSATION BY THE TRANSCRIPTIONAL REGULATOR DREAM		14	-0.56	-1.41	0.091	0.202	1.000	4712	tags=57%, list=21%, signal=73%
125	BIOCARTA_T CELL RECEPTOR SIGNALING PATHWAY		44	-0.43	-1.41	0.057	0.205	1.000	3241	tags=34%, list=15%, signal=40%
126	INOH_JNK CASCADE		16	-0.55	-1.40	0.095	0.207	1.000	983	tags=19%, list=4%, signal=20%
127	BIOCARTA_PHOSPHOLIPASE C-EPSILON PATHWAY		11	-0.61	-1.40	0.089	0.210	1.000	960	tags=27%, list=4%, signal=29%
128	BIOCARTA_FAS SIGNALING PATHWAY (CD95)		19	-0.53	-1.40	0.082	0.209	1.000	4208	tags=47%, list=19%, signal=59%
129	BIOCARTA_IGF-1 SIGNALING PATHWAY		20	-0.52	-1.40	0.077	0.207	1.000	3207	tags=30%, list=15%, signal=35%
130	NCI_OSTEOPONTIN-MEDIATED EVENTS		29	-0.48	-1.40	0.092	0.208	1.000	4134	tags=41%, list=19%, signal=51%
131	NCI_SIGNALING EVENTS REGULATED BY RET TYROSINE KINASE		67	-0.40	-1.40	0.033	0.209	1.000	4728	tags=37%, list=22%, signal=47%
132	NCI_SIGNALING EVENTS MEDIATED BY THE HEDGEHOG FAMILY		62	-0.41	-1.39	0.044	0.214	1.000	4595	tags=39%, list=21%, signal=49%
133	INOH_STABILIZATION AND ACCUMULATION OF CYTOPLASMIC BETA-CATENIN (MAMMAL)		29	-0.47	-1.39	0.066	0.213	1.000	2847	tags=34%, list=13%, signal=40%
134	INOH_STABILIZATION AND ACCUMULATION OF CYTOPLASMIC BETA-CATENIN (CANONICAL)		33	-0.46	-1.39	0.065	0.213	1.000	2847	tags=33%, list=13%, signal=38%
135	INOH_T CELL RECEPTOR SIGNALING (PLC GAMMA, PKC, RAS AND IKK-NF-KAPPAB CASCADE)		26	-0.49	-1.39	0.079	0.213	1.000	3851	tags=50%, list=18%, signal=61%
136	NCI_ANGIOPOIETIN RECEPTOR TIE2-MEDIATED SIGNALING		46	-0.43	-1.39	0.060	0.212	1.000	3002	tags=26%, list=14%, signal=30%
137	NCI_ARF1 PATHWAY		14	-0.55	-1.38	0.121	0.220	1.000	1822	tags=29%, list=8%, signal=31%
138	NCI_PAXILLIN-INDEPENDENT EVENTS MEDIATED BY A4B1 AND A4B7		22	-0.50	-1.38	0.086	0.220	1.000	2117	tags=18%, list=10%, signal=20%
139	REACTOME_TRKA_SIGNALLING_FROM_THE_PLASMA_MEMBRANE		37	-0.45	-1.38	0.065	0.219	1.000	1670	tags=22%, list=8%, signal=23%
140	INOH_T CELL RECEPTOR SIGNALING (PLC GAMMA, PKC, RAS AND ERK CASCADE)		33	-0.46	-1.37	0.083	0.223	1.000	3334	tags=42%, list=15%, signal=50%
141	NETPATH_IFN-GAMMA		71	-0.40	-1.37	0.050	0.222	1.000	2733	tags=30%, list=12%, signal=34%
142	NCI_IL6-MEDIATED SIGNALING EVENTS		43	-0.43	-1.35	0.059	0.247	1.000	4470	tags=44%, list=20%, signal=55%
143	NCI_PRESENILIN ACTION IN NOTCH AND WNT SIGNALING		41	-0.43	-1.35	0.071	0.246	1.000	2854	tags=32%, list=13%, signal=36%
144	BIOCARTA_CONTROL OF GENE EXPRESSION BY VITAMIN D RECEPTOR		24	-0.47	-1.35	0.114	0.245	1.000	979	tags=21%, list=4%, signal=22%
145	REACTOME_THE_ROLE_OF_NEF_IN_HIV_1_REPLICATION_AND_DISEASE_PATHOGENESIS		14	-0.55	-1.35	0.126	0.252	1.000	2867	tags=50%, list=13%, signal=57%
146	BIOCARTA_IL-2 RECEPTOR BETA CHAIN IN T CELL ACTIVATION		46	-0.42	-1.35	0.083	0.253	1.000	3369	tags=33%, list=15%, signal=38%
147	INOH_JAK-STAT PATHWAY AND REGULATION PATHWAY		194	-0.33	-1.34	0.014	0.252	1.000	2867	tags=20%, list=13%, signal=23%
148	NCI_ARF6 SIGNALING EVENTS		120	-0.35	-1.34	0.036	0.256	1.000	4470	tags=32%, list=20%, signal=40%
149	NCI_ARF6 TRAFFICKING EVENTS		120	-0.35	-1.34	0.029	0.260	1.000	4470	tags=32%, list=20%, signal=40%
150	INOH_ADENYLATE CYCLASE ACTIVATION SIGNALING		11	-0.57	-1.34	0.152	0.260	1.000	5114	tags=55%, list=23%, signal=71%
151	NCI_REELIN SIGNALING PATHWAY		27	-0.46	-1.33	0.133	0.264	1.000	1478	tags=15%, list=7%, signal=16%
152	INOH_GENE EXPRESSION OF SOCS BY STAT DIMER		13	-0.55	-1.33	0.139	0.263	1.000	4093	tags=62%, list=19%, signal=76%
153	BIOCARTA_THE CO-STIMULATORY SIGNAL DURING T-CELL ACTIVATION		16	-0.53	-1.33	0.134	0.266	1.000	3334	tags=50%, list=15%, signal=59%
154	BIOCARTA_BCR SIGNALING PATHWAY		29	-0.45	-1.32	0.097	0.269	1.000	983	tags=21%, list=4%, signal=22%
155	BIOCARTA_CELL CYCLE: G1/S CHECK POINT		24	-0.48	-1.32	0.118	0.268	1.000	1658	tags=21%, list=8%, signal=23%
156	NCI_SIGNALING BY AURORA KINASES		88	-0.37	-1.32	0.060	0.269	1.000	2239	tags=23%, list=10%, signal=25%
157	INOH_DROSOPHILA TOLL-LIKE RECEPTOR SIGNALING		193	-0.33	-1.32	0.034	0.269	1.000	2927	tags=20%, list=13%, signal=23%
158	NCI_INSULIN PATHWAY		120	-0.35	-1.32	0.063	0.268	1.000	4470	tags=32%, list=20%, signal=40%
159	INOH_CD4 T CELL RECEPTOR SIGNALING (THROUGH VAV, RAC AND JNK CASCADE		36	-0.44	-1.32	0.090	0.273	1.000	4208	tags=42%, list=19%, signal=51%
160	NETPATH_CD40		29	-0.44	-1.31	0.114	0.273	1.000	3367	tags=38%, list=15%, signal=45%
161	BIOCARTA_SKELETAL MUSCLE HYPERTROPHY IS REGULATED VIA AKT-MTOR PATHWAY		24	-0.47	-1.31	0.128	0.271	1.000	791	tags=21%, list=4%, signal=22%
162	BIOCARTA_MAPKINASE SIGNALING PATHWAY		53	-0.39	-1.31	0.082	0.271	1.000	4728	tags=42%, list=22%, signal=53%
163	BIOCARTA_GATA3 PARTICIPATE IN ACTIVATING THE TH2 CYTOKINE GENES EXPRESSION		18	-0.51	-1.31	0.132	0.269	1.000	1187	tags=22%, list=5%, signal=23%
164	INOH_TOLL-LIKE RECEPTOR SIGNALING PATHWAY (THROUGH LPS, TLR4, MYD88, IRAK, TAK1 AND IKK-NF-KAPPAB CASCADE)(CANONICAL)		22	-0.48	-1.31	0.140	0.269	1.000	4728	tags=50%, list=22%, signal=64%
165	BIOCARTA_RAS SIGNALING PATHWAY		19	-0.50	-1.31	0.159	0.271	1.000	4703	tags=53%, list=21%, signal=67%
166	REACTOME_DEADENYLATION_OF_MRNA		10	-0.58	-1.31	0.167	0.272	1.000	190	tags=20%, list=1%, signal=20%
167	INOH_G ALPHA S GDP-GTP EXCHANGE SIGNALING		107	-0.35	-1.30	0.046	0.280	1.000	3207	tags=21%, list=15%, signal=25%
168	NCI_P75(NTR)-MEDIATED SIGNALING		165	-0.33	-1.30	0.033	0.282	1.000	4728	tags=38%, list=22%, signal=48%
169	BIOCARTA_GAMMA-AMINOBUTYRIC ACID RECEPTOR LIFE CYCLE PATHWAY		14	-0.52	-1.29	0.183	0.301	1.000	3864	tags=36%, list=18%, signal=43%
170	REACTOME_SIGNALING_IN_IMMUNE_SYSTEM		138	-0.33	-1.28	0.054	0.300	1.000	4157	tags=34%, list=19%, signal=42%
171	NCI_SYNDECAN-1-MEDIATED SIGNALING EVENTS		157	-0.33	-1.28	0.054	0.299	1.000	2331	tags=18%, list=11%, signal=20%
172	INOH_NEGATIVE REGULATION OF (G ALPHA I GDP-GTP EXCHANGE SIGNALING)		18	-0.49	-1.28	0.157	0.298	1.000	1014	tags=17%, list=5%, signal=17%
173	NCI_FOXA1 TRANSCRIPTION FACTOR NETWORK		35	-0.42	-1.28	0.136	0.298	1.000	1508	tags=20%, list=7%, signal=21%
174	BIOCARTA_ROLE OF MEF2D IN T-CELL APOPTOSIS		25	-0.45	-1.28	0.145	0.296	1.000	2867	tags=36%, list=13%, signal=41%
175	BIOCARTA_REGULATION OF EIF-4E AND P70S6 KINASE		22	-0.47	-1.28	0.141	0.297	1.000	2672	tags=27%, list=12%, signal=31%
176	BIOCARTA_EICOSANOID METABOLISM		20	-0.48	-1.28	0.148	0.299	1.000	2061	tags=20%, list=9%, signal=22%
177	NCI_IL12 SIGNALING MEDIATED BY STAT4		27	-0.44	-1.28	0.137	0.298	1.000	2665	tags=41%, list=12%, signal=46%
178	NCI_SIGNALING EVENTS ACTIVATED BY HEPATOCYTE GROWTH FACTOR RECEPTOR (C-MET)		149	-0.33	-1.28	0.065	0.301	1.000	2331	tags=18%, list=11%, signal=20%
179	REACTOME_EGFR_DOWNREGULATION		11	-0.55	-1.27	0.162	0.301	1.000	5460	tags=55%, list=25%, signal=73%
180	REACTOME_TIE2_SIGNALING		12	-0.54	-1.27	0.190	0.309	1.000	3935	tags=33%, list=18%, signal=41%
181	INOH_P38 CASCADE		12	-0.54	-1.27	0.201	0.308	1.000	5003	tags=50%, list=23%, signal=65%
182	REACTOME_DEATH_RECEPTOR__SIGNALLING		12	-0.52	-1.26	0.185	0.314	1.000	1399	tags=25%, list=6%, signal=27%
183	BIOCARTA_IL 3 SIGNALING PATHWAY		11	-0.55	-1.25	0.207	0.325	1.000	4470	tags=64%, list=20%, signal=80%
184	REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS		10	-0.57	-1.25	0.221	0.331	1.000	2367	tags=40%, list=11%, signal=45%
185	CELLMAP_ALPHA6BETA4INTEGRIN		49	-0.39	-1.25	0.129	0.330	1.000	2672	tags=16%, list=12%, signal=19%
186	NCI_THROMBOXANE A2 RECEPTOR SIGNALING		50	-0.38	-1.25	0.151	0.329	1.000	3158	tags=26%, list=14%, signal=30%
187	REACTOME_TRAF6_MEDIATED_INDUCTION_OF_THE_ANTIVIRAL_CYTOKINE_IFN_ALPHA_BETA_CASCADE		13	-0.52	-1.25	0.190	0.331	1.000	4728	tags=46%, list=22%, signal=59%
188	NCI_CALCIUM SIGNALING IN THE CD4+ TCR PATHWAY		22	-0.45	-1.24	0.165	0.331	1.000	983	tags=14%, list=4%, signal=14%
189	INOH_RAP1 ACTIVATION SIGNALING (THROUGH CAMP. PKA, CBL AND C3G)		13	-0.50	-1.24	0.207	0.337	1.000	2952	tags=31%, list=13%, signal=36%
190	REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES		16	-0.48	-1.24	0.194	0.340	1.000	4431	tags=69%, list=20%, signal=86%
191	NCI_COREGULATION OF ANDROGEN RECEPTOR ACTIVITY		44	-0.38	-1.23	0.144	0.344	1.000	4535	tags=36%, list=21%, signal=46%
192	BIOCARTA_ERK AND PI-3 KINASE ARE NECESSARY FOR COLLAGEN BINDING IN CORNEAL EPITHELIA		30	-0.42	-1.23	0.190	0.347	1.000	3673	tags=37%, list=17%, signal=44%
193	NCI_P38 SIGNALING MEDIATED BY MAPKAP KINASES		21	-0.46	-1.22	0.206	0.353	1.000	3007	tags=29%, list=14%, signal=33%
194	REACTOME_TOLL_LIKE_RECEPTOR_3__TLR3__CASCADE		15	-0.48	-1.22	0.204	0.352	1.000	2824	tags=33%, list=13%, signal=38%
195	REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS		12	-0.52	-1.22	0.209	0.352	1.000	1399	tags=25%, list=6%, signal=27%
196	REACTOME_TOLL_RECEPTOR_CASCADES		27	-0.43	-1.21	0.212	0.365	1.000	2962	tags=30%, list=14%, signal=34%
197	BIOCARTA_INDUCTION OF APOPTOSIS THROUGH DR3 AND DR4/5 DEATH RECEPTORS		19	-0.45	-1.21	0.216	0.377	1.000	2899	tags=37%, list=13%, signal=42%
198	INOH_NEGATIVE FEEDBACK REGULATION PATHWAY OF TGF BETA SUPERFAMILY SIGNALING BY (BINDING OF SMAD6/7 AND TGF BETA RECEPTOR I)		12	-0.50	-1.21	0.264	0.375	1.000	3520	tags=33%, list=16%, signal=40%
199	INOH_GENE EXPROSSION OF SMAD6/7 BY R-SMAD:SMAD4		12	-0.50	-1.21	0.228	0.375	1.000	3520	tags=33%, list=16%, signal=40%
200	BIOCARTA_LISSENCEPHALY GENE (LIS1) IN NEURONAL MIGRATION AND DEVELOPMENT		15	-0.48	-1.20	0.237	0.375	1.000	2259	tags=20%, list=10%, signal=22%
201	INOH_NEGATIVE REGULATION OF (NUCLEAR IMPORT OF R-SMAD:SMAD4) IN TGF BETA SUPER FAMILY SIGNALING PATHWAY		10	-0.53	-1.20	0.243	0.375	1.000	4333	tags=50%, list=20%, signal=62%
202	BIOCARTA_TOLL-LIKE RECEPTOR PATHWAY		35	-0.39	-1.20	0.197	0.381	1.000	4728	tags=37%, list=22%, signal=47%
203	NCI_PROTEOGYLCAN SYNDECAN-MEDIATED SIGNALING EVENTS		241	-0.29	-1.20	0.074	0.385	1.000	4350	tags=27%, list=20%, signal=34%
204	BIOCARTA_THE INFORMATION PROCESSING PATHWAY AT THE IFN BETA ENHANCER		27	-0.42	-1.19	0.222	0.384	1.000	2722	tags=33%, list=12%, signal=38%
205	NCI_CERAMIDE SIGNALING PATHWAY		42	-0.38	-1.19	0.200	0.383	1.000	2978	tags=29%, list=14%, signal=33%
206	BIOCARTA_PDGF SIGNALING PATHWAY		25	-0.42	-1.19	0.234	0.382	1.000	983	tags=16%, list=4%, signal=17%
207	NCI_GLYPICAN 3 NETWORK		57	-0.35	-1.19	0.188	0.387	1.000	2449	tags=23%, list=11%, signal=26%
208	CELLMAP_WNT		66	-0.35	-1.19	0.175	0.385	1.000	2854	tags=23%, list=13%, signal=26%
209	BIOCARTA_MULTIPLE ANTIAPOPTOTIC PATHWAYS FROM IGF-1R SIGNALING LEAD TO BAD PHOSPHORYLATION		13	-0.48	-1.18	0.264	0.392	1.000	4703	tags=46%, list=21%, signal=59%
210	CELLMAP_EGFR1		122	-0.31	-1.18	0.149	0.399	1.000	3504	tags=25%, list=16%, signal=29%
211	INOH_RAF ACTIVATION SIGNALING (THROUGH GRB2 AND SOS)		12	-0.50	-1.17	0.270	0.407	1.000	5003	tags=67%, list=23%, signal=86%
212	INOH_STABILIZATION AND ACCUMULATION OF CYTOPLASMIC BETA-CATENIN (XENOPUS)		15	-0.47	-1.17	0.264	0.407	1.000	2277	tags=33%, list=10%, signal=37%
213	BIOCARTA_TNFR1 SIGNALING PATHWAY		17	-0.45	-1.17	0.261	0.406	1.000	1399	tags=24%, list=6%, signal=25%
214	NCI_RXR AND RAR HETERODIMERIZATION WITH OTHER NUCLEAR RECEPTOR		19	-0.44	-1.17	0.265	0.405	1.000	1770	tags=21%, list=8%, signal=23%
215	NCI_SPHINGOSINE 1-PHOSPHATE (S1P) PATHWAY		120	-0.31	-1.17	0.137	0.406	1.000	3002	tags=24%, list=14%, signal=28%
216	BIOCARTA_MCALPAIN AND FRIENDS IN CELL MOTILITY		28	-0.40	-1.17	0.256	0.407	1.000	4470	tags=36%, list=20%, signal=45%
217	BIOCARTA_UCALPAIN AND FRIENDS IN CELL SPREAD		15	-0.47	-1.17	0.269	0.405	1.000	4619	tags=40%, list=21%, signal=51%
218	BIOCARTA_ROLE OF PI3K SUBUNIT P85 IN REGULATION OF ACTIN ORGANIZATION AND CELL MIGRATION		16	-0.46	-1.16	0.253	0.421	1.000	4619	tags=44%, list=21%, signal=55%
219	INOH_[NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING)		18	-0.44	-1.16	0.271	0.420	1.000	3814	tags=28%, list=17%, signal=34%
220	NCI_INTEGRINS IN ANGIOGENESIS		62	-0.34	-1.16	0.224	0.421	1.000	2558	tags=18%, list=12%, signal=20%
221	BIOCARTA_ER ASSOCIATED DEGRADATION (ERAD) PATHWAY		16	-0.45	-1.16	0.274	0.421	1.000	3421	tags=38%, list=16%, signal=44%
222	NCI_E-CADHERIN SIGNALING IN THE NASCENT ADHERENS JUNCTION		43	-0.37	-1.15	0.257	0.421	1.000	998	tags=14%, list=5%, signal=15%
223	BIOCARTA_IL 2 SIGNALING PATHWAY		13	-0.48	-1.15	0.285	0.420	1.000	4470	tags=62%, list=20%, signal=77%
224	BIOCARTA_PROTEIN KINASE A AT THE CENTROSOME		10	-0.50	-1.15	0.292	0.425	1.000	4619	tags=50%, list=21%, signal=63%
225	INOH_RAF ACTIVATION SIGNALING (THROUGH RASGRP)		10	-0.51	-1.15	0.294	0.424	1.000	2890	tags=40%, list=13%, signal=46%
226	INOH_SIGNALING WITH WNT (XENOPUS)		15	-0.47	-1.14	0.309	0.432	1.000	2277	tags=33%, list=10%, signal=37%
227	BIOCARTA_INTERNAL RIBOSOME ENTRY PATHWAY		15	-0.46	-1.14	0.290	0.440	1.000	4582	tags=53%, list=21%, signal=67%
228	NETPATH_TIE1_TEK		25	-0.41	-1.14	0.297	0.443	1.000	4619	tags=44%, list=21%, signal=56%
229	INOH_SIGNALING WITH WNT (MAMMAL)		53	-0.34	-1.14	0.247	0.442	1.000	2847	tags=21%, list=13%, signal=24%
230	INOH_SIGNALING WITH WNT (CANONICAL)		57	-0.34	-1.13	0.271	0.444	1.000	2847	tags=21%, list=13%, signal=24%
231	NCI_CANONICAL WNT SIGNALING PATHWAY		49	-0.35	-1.13	0.262	0.442	1.000	2449	tags=22%, list=11%, signal=25%
232	NCI_FC-EPSILON RECEPTOR I SIGNALING IN MAST CELLS		54	-0.34	-1.13	0.245	0.440	1.000	3334	tags=30%, list=15%, signal=35%
233	BIOCARTA_INTEGRIN SIGNALING PATHWAY		33	-0.37	-1.13	0.266	0.439	1.000	1041	tags=18%, list=5%, signal=19%
234	NCI_TRK RECEPTOR SIGNALING MEDIATED BY PI3K AND PLC-GAMMA		57	-0.33	-1.13	0.213	0.441	1.000	4712	tags=39%, list=21%, signal=49%
235	BIOCARTA_B CELL SURVIVAL PATHWAY		13	-0.46	-1.13	0.316	0.449	1.000	1230	tags=23%, list=6%, signal=24%
236	BIOCARTA_TREFOIL FACTORS INITIATE MUCOSAL HEALING		35	-0.37	-1.12	0.295	0.452	1.000	4728	tags=49%, list=22%, signal=62%
237	NCI_WNT SIGNALING		49	-0.35	-1.12	0.272	0.454	1.000	2449	tags=22%, list=11%, signal=25%
238	NCI_S1P2 PATHWAY		23	-0.41	-1.12	0.327	0.453	1.000	4619	tags=43%, list=21%, signal=55%
239	REACTOME_FORMATION_OF_PLATELET_PLUG		79	-0.31	-1.12	0.259	0.454	1.000	1014	tags=11%, list=5%, signal=12%
240	BIOCARTA_TGF BETA SIGNALING PATHWAY		20	-0.42	-1.12	0.320	0.458	1.000	2558	tags=30%, list=12%, signal=34%
241	REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION		10	-0.49	-1.11	0.336	0.458	1.000	1777	tags=50%, list=8%, signal=54%
242	NCI_FOXA TRANSCRIPTION FACTOR NETWORKS		66	-0.32	-1.11	0.256	0.456	1.000	1850	tags=15%, list=8%, signal=16%
243	REACTOME_SIGNALING_BY_GPCR		139	-0.29	-1.11	0.224	0.457	1.000	3044	tags=14%, list=14%, signal=16%
244	BIOCARTA_ROLE OF MITOCHONDRIA IN APOPTOTIC SIGNALING		12	-0.46	-1.10	0.333	0.471	1.000	1792	tags=42%, list=8%, signal=45%
245	REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE_1		12	-0.47	-1.10	0.345	0.470	1.000	836	tags=17%, list=4%, signal=17%
246	NCI_SIGNALING MEDIATED BY P38-ALPHA AND P38-BETA		47	-0.34	-1.10	0.300	0.480	1.000	3512	tags=30%, list=16%, signal=35%
247	BIOCARTA_MELANOCYTE DEVELOPMENT AND PIGMENTATION PATHWAY		13	-0.45	-1.10	0.363	0.481	1.000	5238	tags=62%, list=24%, signal=81%
248	BIOCARTA_ANGIOTENSIN II MEDIATED ACTIVATION OF JNK PATHWAY VIA PYK2 DEPENDENT SIGNALING		32	-0.37	-1.10	0.327	0.481	1.000	4703	tags=47%, list=21%, signal=60%
249	INOH_TOLL-LIKE RECEPTOR SIGNALING PATHWAY (P38 CASCADE)		24	-0.39	-1.09	0.324	0.481	1.000	4458	tags=38%, list=20%, signal=47%
250	INOH_NEGATIVE REGULATION OF (G ALPHA GDP-GTP EXCHANGE SIGNALING)		17	-0.42	-1.09	0.344	0.482	1.000	2676	tags=18%, list=12%, signal=20%
251	BIOCARTA_THE IGF-1 RECEPTOR AND LONGEVITY		15	-0.44	-1.09	0.351	0.482	1.000	791	tags=13%, list=4%, signal=14%
252	INOH_IL-1 SIGNALING PATHWAY (THROUGH P38 CASCADE)		24	-0.39	-1.09	0.351	0.487	1.000	5003	tags=33%, list=23%, signal=43%
253	BIOCARTA_ATTENUATION OF GPCR SIGNALING		11	-0.46	-1.09	0.351	0.487	1.000	960	tags=18%, list=4%, signal=19%
254	BIOCARTA_NITRIC OXIDE SIGNALING PATHWAY		16	-0.43	-1.08	0.369	0.489	1.000	960	tags=19%, list=4%, signal=20%
255	BIOCARTA_METS AFFECT ON MACROPHAGE DIFFERENTIATION		17	-0.41	-1.08	0.357	0.492	1.000	1748	tags=24%, list=8%, signal=26%
256	CELLMAP_TGFBR		105	-0.29	-1.08	0.279	0.493	1.000	3581	tags=27%, list=16%, signal=32%
257	INOH_NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING)		17	-0.42	-1.08	0.364	0.495	1.000	2676	tags=18%, list=12%, signal=20%
258	REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING		14	-0.43	-1.07	0.339	0.503	1.000	2797	tags=36%, list=13%, signal=41%
259	BIOCARTA_PHOSPHOINOSITIDES AND THEIR DOWNSTREAM TARGETS		20	-0.39	-1.07	0.359	0.505	1.000	791	tags=15%, list=4%, signal=16%
260	BIOCARTA_STATHMIN AND BREAST CANCER RESISTANCE TO ANTIMICROTUBULE AGENTS		16	-0.41	-1.07	0.376	0.509	1.000	960	tags=19%, list=4%, signal=20%
261	NCI_LPA4-MEDIATED SIGNALING EVENTS		14	-0.43	-1.07	0.347	0.508	1.000	5114	tags=43%, list=23%, signal=56%
262	NCI_NONGENOTROPIC ANDROGEN SIGNALING		24	-0.38	-1.07	0.381	0.511	1.000	1014	tags=13%, list=5%, signal=13%
263	BIOCARTA_NFAT AND HYPERTROPHY OF THE HEART		42	-0.33	-1.06	0.337	0.515	1.000	1912	tags=17%, list=9%, signal=18%
264	REACTOME_NEURORANSMITTER_RECEPTOR_BINDING_AND_DOWNSTREAM_TRANSMISSION_IN_THE__POSTSYNAPTIC_CELL		23	-0.39	-1.06	0.377	0.516	1.000	4712	tags=48%, list=21%, signal=61%
265	INOH_PLC BETA SIGNALING		19	-0.41	-1.06	0.396	0.515	1.000	534	tags=16%, list=2%, signal=16%
266	REACTOME_PI3K_CASCADE		13	-0.44	-1.06	0.398	0.516	1.000	791	tags=15%, list=4%, signal=16%
267	INOH_IL-1_SIGNALING(THROUGH_JNK_CASCADE)(CANONICAL)		24	-0.38	-1.06	0.384	0.518	1.000	5003	tags=33%, list=23%, signal=43%
268	BIOCARTA_HOW DOES SALMONELLA HIJACK A CELL		11	-0.46	-1.06	0.397	0.519	1.000	4199	tags=45%, list=19%, signal=56%
269	REACTOME_CLATHRIN_DERIVED_VESICLE_BUDDING		14	-0.43	-1.05	0.374	0.522	1.000	2797	tags=36%, list=13%, signal=41%
270	BIOCARTA_PHOSPHORYLATION OF MEK1 BY CDK5/P35 DOWN REGULATES THE MAP KINASE PATHWAY		13	-0.44	-1.05	0.379	0.521	1.000	5003	tags=46%, list=23%, signal=60%
271	NCI_RAS SIGNALING IN THE CD4+ TCR PATHWAY		33	-0.35	-1.05	0.375	0.520	1.000	5152	tags=42%, list=23%, signal=55%
272	NCI_EPHA2 FORWARD SIGNALING		17	-0.40	-1.05	0.389	0.519	1.000	92	tags=12%, list=0%, signal=12%
273	HUMANCYC_FATTY ACID BETA-OXIDATION I		16	-0.41	-1.05	0.416	0.525	1.000	1777	tags=31%, list=8%, signal=34%
274	BIOCARTA_VEGF HYPOXIA AND ANGIOGENESIS		27	-0.36	-1.05	0.393	0.524	1.000	791	tags=11%, list=4%, signal=12%
275	NCI_REGULATION OF RETINOBLASTOMA PROTEIN		60	-0.31	-1.04	0.358	0.529	1.000	2013	tags=18%, list=9%, signal=20%
276	INOH_NEGATIVE REGULATION OF (TRANSCRIPTION BY R-SMAD:SMAD4) IN TGF BETA SUPER FAMILY SIGNALING PATHWAY		17	-0.39	-1.04	0.417	0.537	1.000	1748	tags=24%, list=8%, signal=26%
277	BIOCARTA_ROLE OF MAL IN RHO-MEDIATED ACTIVATION OF SRF		17	-0.41	-1.03	0.426	0.545	1.000	2789	tags=24%, list=13%, signal=27%
278	BIOCARTA_TPO SIGNALING PATHWAY		23	-0.37	-1.03	0.406	0.546	1.000	3207	tags=30%, list=15%, signal=36%
279	BIOCARTA_TRANSCRIPTION FACTOR CREB AND ITS EXTRACELLULAR SIGNALS		25	-0.36	-1.03	0.417	0.553	1.000	4712	tags=40%, list=21%, signal=51%
280	BIOCARTA_STRESS INDUCTION OF HSP REGULATION		14	-0.41	-1.03	0.424	0.552	1.000	1960	tags=36%, list=9%, signal=39%
281	NCI_TRK RECEPTOR SIGNALING MEDIATED BY THE MAPK PATHWAY		33	-0.34	-1.02	0.407	0.560	1.000	4712	tags=39%, list=21%, signal=50%
282	REACTOME_CLASS_B_2__SECRETIN_FAMILY_RECEPTORS_		23	-0.36	-1.02	0.409	0.562	1.000	11	tags=4%, list=0%, signal=4%
283	NETPATH_IL9		10	-0.44	-1.02	0.412	0.564	1.000	1268	tags=20%, list=6%, signal=21%
284	BIOCARTA_FMLP INDUCED CHEMOKINE GENE EXPRESSION IN HMC-1 CELLS		29	-0.35	-1.01	0.447	0.573	1.000	5245	tags=45%, list=24%, signal=59%
285	BIOCARTA_REGULATION OF CK1/CDK5 BY TYPE 1 GLUTAMATE RECEPTORS		23	-0.37	-1.01	0.445	0.575	1.000	1590	tags=17%, list=7%, signal=19%
286	INOH_TOLL-LIKE RECEPTOR SIGNALING PATHWAY (THROUGH JNK CASCADE)(CANONICAL)		23	-0.35	-1.01	0.454	0.580	1.000	5003	tags=39%, list=23%, signal=51%
287	BIOCARTA_APOPTOTIC SIGNALING IN RESPONSE TO DNA DAMAGE		14	-0.40	-1.00	0.470	0.594	1.000	1792	tags=36%, list=8%, signal=39%
288	REACTOME_PLATELET_ACTIVATION_TRIGGERS		24	-0.35	-0.99	0.462	0.611	1.000	3836	tags=38%, list=17%, signal=45%
289	BIOCARTA_INFLUENCE OF RAS AND RHO PROTEINS ON G1 TO S TRANSITION		27	-0.34	-0.99	0.472	0.610	1.000	4728	tags=44%, list=22%, signal=57%
290	BIOCARTA_REGULATION OF P27 PHOSPHORYLATION DURING CELL CYCLE PROGRESSION		11	-0.42	-0.99	0.485	0.610	1.000	82	tags=9%, list=0%, signal=9%
291	BIOCARTA_LINKS BETWEEN PYK2 AND MAP KINASES		25	-0.35	-0.99	0.449	0.610	1.000	3207	tags=32%, list=15%, signal=37%
292	BIOCARTA_AGRIN IN POSTSYNAPTIC DIFFERENTIATION		44	-0.31	-0.98	0.494	0.612	1.000	4237	tags=20%, list=19%, signal=25%
293	BIOCARTA_Y BRANCHING OF ACTIN FILAMENTS		16	-0.38	-0.98	0.479	0.611	1.000	4322	tags=50%, list=20%, signal=62%
294	NCI_SYNDECAN-4-MEDIATED SIGNALING EVENTS		49	-0.29	-0.97	0.486	0.633	1.000	4157	tags=31%, list=19%, signal=38%
295	BIOCARTA_CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (CFTR) AND BETA 2 ADRENERGIC RECEPTOR (B2AR) PATHWAY		18	-0.37	-0.97	0.480	0.643	1.000	960	tags=17%, list=4%, signal=17%
296	NCI_ARF6 DOWNSTREAM PATHWAY		27	-0.33	-0.96	0.531	0.643	1.000	2705	tags=26%, list=12%, signal=30%
297	CELLMAP_HEDGEHOG		15	-0.38	-0.96	0.503	0.643	1.000	4595	tags=47%, list=21%, signal=59%
298	NCI_CELLULAR ROLES OF ANTHRAX TOXIN		15	-0.38	-0.96	0.525	0.643	1.000	5003	tags=33%, list=23%, signal=43%
299	CELLMAP_ANDROGENRECEPTOR		74	-0.27	-0.96	0.540	0.642	1.000	2475	tags=20%, list=11%, signal=23%
300	NCI_NEUROTROPHIC FACTOR-MEDIATED TRK RECEPTOR SIGNALING		93	-0.27	-0.96	0.519	0.654	1.000	4205	tags=28%, list=19%, signal=34%
301	NCI_SIGNALING EVENTS MEDIATED BY HDAC CLASS II		31	-0.32	-0.95	0.537	0.658	1.000	4591	tags=39%, list=21%, signal=49%
302	BIOCARTA_ROLE OF ERBB2 IN SIGNAL TRANSDUCTION AND ONCOLOGY		28	-0.32	-0.95	0.539	0.657	1.000	5003	tags=36%, list=23%, signal=46%
303	INOH_TOLL-LIKE RECEPTOR SIGNALING PATHWAY (THROUGH ECSIT, MEKK1, MKKS, P38 CASCADE)		20	-0.35	-0.95	0.523	0.657	1.000	5003	tags=40%, list=23%, signal=52%
304	NETPATH_IL-7		15	-0.38	-0.95	0.544	0.656	1.000	3699	tags=47%, list=17%, signal=56%
305	HUMANCYC_FATTY ACID BETA-OXIDATION II (CORE PATHWAY)		16	-0.37	-0.95	0.536	0.657	1.000	1896	tags=25%, list=9%, signal=27%
306	REACTOME_INTEGRIN_ALPHAIIBBETA3_SIGNALING		16	-0.37	-0.95	0.532	0.655	1.000	1661	tags=19%, list=8%, signal=20%
307	REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS		19	-0.35	-0.95	0.540	0.658	1.000	4712	tags=47%, list=21%, signal=60%
308	REACTOME_ACTIVATION_OF_NMDA_RECEPTOR_UPON_GLUTAMATE_BINDING_AND_POSTSYNAPTIC_EVENTS		19	-0.35	-0.94	0.538	0.663	1.000	4712	tags=47%, list=21%, signal=60%
309	REACTOME_HEMOSTASIS		144	-0.24	-0.94	0.585	0.672	1.000	3504	tags=20%, list=16%, signal=24%
310	NCI_SYNDECAN-2-MEDIATED SIGNALING EVENTS		72	-0.27	-0.94	0.585	0.670	1.000	4163	tags=25%, list=19%, signal=31%
311	REACTOME_INORGANIC_CATION_ANION_SLC_TRANSPORTERS		11	-0.40	-0.93	0.556	0.681	1.000	170	tags=9%, list=1%, signal=9%
312	REACTOME_MEMBRANE_TRAFFICKING		24	-0.33	-0.93	0.550	0.681	1.000	2797	tags=25%, list=13%, signal=29%
313	REACTOME_PLATELET_ACTIVATION		66	-0.27	-0.93	0.628	0.683	1.000	1014	tags=11%, list=5%, signal=11%
314	BIOCARTA_AKAP95 ROLE IN MITOSIS AND CHROMOSOME DYNAMICS		11	-0.40	-0.93	0.558	0.684	1.000	3831	tags=45%, list=17%, signal=55%
315	REACTOME_PLATELET_AGGREGATION__PLUG_FORMATION_		17	-0.35	-0.91	0.586	0.702	1.000	1661	tags=18%, list=8%, signal=19%
316	BIOCARTA_MECHANISM OF GENE REGULATION BY PEROXISOME PROLIFERATORS VIA PPARA		36	-0.30	-0.91	0.571	0.701	1.000	1896	tags=22%, list=9%, signal=24%
317	BIOCARTA_REGULATION OF EIF2		10	-0.40	-0.91	0.567	0.699	1.000	77	tags=10%, list=0%, signal=10%
318	BIOCARTA_ADP-RIBOSYLATION FACTOR		18	-0.35	-0.91	0.560	0.704	1.000	5237	tags=44%, list=24%, signal=58%
319	REACTOME_SYNAPTIC_TRANSMISSION		44	-0.29	-0.91	0.626	0.702	1.000	1670	tags=16%, list=8%, signal=17%
320	REACTOME_TOLL_LIKE_RECEPTOR_4__TLR4__CASCADE		10	-0.41	-0.91	0.584	0.700	1.000	2962	tags=40%, list=14%, signal=46%
321	REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS		54	-0.27	-0.91	0.640	0.702	1.000	2862	tags=13%, list=13%, signal=15%
322	REACTOME_IRS_MEDIATED_SIGNALLING		21	-0.33	-0.90	0.594	0.709	1.000	791	tags=10%, list=4%, signal=10%
323	REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES		44	-0.29	-0.90	0.644	0.707	1.000	1670	tags=16%, list=8%, signal=17%
324	BIOCARTA_IL 4 SIGNALING PATHWAY		11	-0.39	-0.90	0.582	0.706	1.000	2036	tags=27%, list=9%, signal=30%
325	BIOCARTA_APOPTOTIC DNA-FRAGMENTATION AND TISSUE HOMEOSTASIS		10	-0.39	-0.90	0.590	0.710	1.000	2150	tags=30%, list=10%, signal=33%
326	NCI_STABILIZATION AND EXPANSION OF THE E-CADHERIN ADHERENS JUNCTION		19	-0.34	-0.89	0.630	0.718	1.000	4619	tags=37%, list=21%, signal=47%
327	BIOCARTA_MAP KINASE INACTIVATION OF SMRT COREPRESSOR		17	-0.35	-0.89	0.611	0.723	1.000	4470	tags=41%, list=20%, signal=52%
328	REACTOME_INSULIN_RECEPTOR_SIGNALLING_CASCADE		23	-0.32	-0.89	0.627	0.725	1.000	791	tags=9%, list=4%, signal=9%
329	BIOCARTA_CCR3 SIGNALING IN EOSINOPHILS		22	-0.33	-0.89	0.633	0.726	1.000	277	tags=9%, list=1%, signal=9%
330	REACTOME_NEUROTRANSMITTER_RELEASE_CYCLE		16	-0.34	-0.89	0.618	0.724	1.000	859	tags=13%, list=4%, signal=13%
331	BIOCARTA_HYPOXIA-INDUCIBLE FACTOR IN THE CARDIVASCULAR SYSTEM		13	-0.38	-0.88	0.613	0.730	1.000	1946	tags=23%, list=9%, signal=25%
332	REACTOME_SIGNALING_BY_INSULIN_RECEPTOR		23	-0.32	-0.88	0.620	0.733	1.000	791	tags=9%, list=4%, signal=9%
333	REACTOME_IRS_RELATED_EVENTS		22	-0.32	-0.87	0.650	0.742	1.000	791	tags=9%, list=4%, signal=9%
334	BIOCARTA_RAC1 CELL MOTILITY SIGNALING PATHWAY		30	-0.29	-0.87	0.659	0.741	1.000	2200	tags=17%, list=10%, signal=18%
335	BIOCARTA_PHOSPHOLIPIDS AS SIGNALLING INTERMEDIARIES		30	-0.30	-0.87	0.684	0.741	1.000	5245	tags=40%, list=24%, signal=52%
336	BIOCARTA_ALK IN CARDIAC MYOCYTES		26	-0.30	-0.87	0.653	0.747	1.000	623	tags=12%, list=3%, signal=12%
337	INOH_NOTCH SECRETORY PATHWAY		25	-0.30	-0.86	0.679	0.758	1.000	2898	tags=32%, list=13%, signal=37%
338	INOH_INTEGRIN SIGNALING PATHWAY		91	-0.23	-0.86	0.741	0.758	1.000	4157	tags=24%, list=19%, signal=30%
339	REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS		56	-0.26	-0.86	0.739	0.763	1.000	415	tags=7%, list=2%, signal=7%
340	REACTOME_STEROID_HORMONES		14	-0.35	-0.85	0.651	0.763	1.000	2754	tags=14%, list=13%, signal=16%
341	BIOCARTA_DOUBLE STRANDED RNA INDUCED GENE EXPRESSION		12	-0.35	-0.85	0.645	0.767	1.000	4728	tags=58%, list=22%, signal=74%
342	INOH_CANONICAL NOTCH SIGNALING PATHWAY		25	-0.30	-0.85	0.690	0.772	1.000	2898	tags=32%, list=13%, signal=37%
343	REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH		18	-0.32	-0.85	0.689	0.771	1.000	3359	tags=33%, list=15%, signal=39%
344	NCI_S1P3 PATHWAY		24	-0.30	-0.85	0.718	0.769	1.000	4845	tags=46%, list=22%, signal=59%
345	REACTOME_CLASS_A_1__RHODOPSIN_LIKE_RECEPTORS_		90	-0.23	-0.84	0.823	0.773	1.000	1807	tags=8%, list=8%, signal=8%
346	BIOCARTA_HYPOXIA AND P53 IN THE CARDIOVASCULAR SYSTEM		19	-0.31	-0.83	0.712	0.791	1.000	1946	tags=21%, list=9%, signal=23%
347	BIOCARTA_SIGNALING PATHWAY FROM G-PROTEIN FAMILIES		24	-0.29	-0.83	0.718	0.789	1.000	5245	tags=58%, list=24%, signal=77%
348	NCI_A6B1 AND A6B4 INTEGRIN SIGNALING		43	-0.26	-0.83	0.782	0.787	1.000	289	tags=5%, list=1%, signal=5%
349	REACTOME_GRB2_EVENTS_IN_EGFR_SIGNALING		10	-0.37	-0.83	0.696	0.787	1.000	5003	tags=50%, list=23%, signal=65%
350	BIOCARTA_RHO CELL MOTILITY SIGNALING PATHWAY		26	-0.29	-0.83	0.716	0.787	1.000	3380	tags=31%, list=15%, signal=36%
351	REACTOME_SHC_EVENTS_IN_EGFR_SIGNALING		11	-0.36	-0.83	0.711	0.785	1.000	5003	tags=45%, list=23%, signal=59%
352	REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS		21	-0.30	-0.82	0.728	0.790	1.000	1792	tags=19%, list=8%, signal=21%
353	REACTOME_PEROXISOMAL_LIPID_METABOLISM		11	-0.35	-0.82	0.708	0.796	1.000	5843	tags=55%, list=27%, signal=74%
354	INOH_TOLL-LIKE RECEPTOR SIGNALING PATHWAY (THROUGH ECSIT, MEKK1, MKKS, JNK CASCADE)		19	-0.30	-0.80	0.776	0.815	1.000	5003	tags=37%, list=23%, signal=48%
355	INOH_CANONICAL WNT SIGNALING PATHWAY		74	-0.23	-0.80	0.860	0.814	1.000	2912	tags=18%, list=13%, signal=20%
356	BIOCARTA_P38 MAPK SIGNALING PATHWAY		28	-0.28	-0.80	0.779	0.816	1.000	4208	tags=39%, list=19%, signal=49%
357	INOH_MAMMALIAN WNT SIGNALING PATHWAY		70	-0.23	-0.79	0.889	0.832	1.000	2912	tags=17%, list=13%, signal=20%
358	NETPATH_BDNF		31	-0.25	-0.76	0.837	0.870	1.000	4470	tags=29%, list=20%, signal=36%
359	BIOCARTA_ENDOCYTOTIC ROLE OF NDK PHOSPHINS AND DYNAMIN		15	-0.30	-0.75	0.796	0.876	1.000	4026	tags=40%, list=18%, signal=49%
360	NCI_FGF SIGNALING PATHWAY		46	-0.22	-0.72	0.925	0.908	1.000	3819	tags=22%, list=17%, signal=26%
361	INOH_XENOPUS AXIS FORMATION WNT SIGNALING PATHWAY		40	-0.23	-0.72	0.911	0.907	1.000	2912	tags=15%, list=13%, signal=17%
362	REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER		13	-0.29	-0.71	0.853	0.915	1.000	5515	tags=62%, list=25%, signal=82%
363	REACTOME_SPHINGOLIPID_METABOLISM		10	-0.32	-0.71	0.828	0.913	1.000	2634	tags=30%, list=12%, signal=34%
364	REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_INITIATION		14	-0.28	-0.70	0.854	0.920	1.000	5515	tags=57%, list=25%, signal=76%
365	NCI_EPHB FORWARD SIGNALING		37	-0.22	-0.69	0.924	0.920	1.000	2952	tags=16%, list=13%, signal=19%
366	BIOCARTA_MTOR SIGNALING PATHWAY		22	-0.25	-0.68	0.904	0.926	1.000	791	tags=9%, list=4%, signal=9%
367	NCI_AMB2 INTEGRIN SIGNALING		47	-0.21	-0.66	0.976	0.942	1.000	3158	tags=17%, list=14%, signal=20%
368	INOH_GROWTH HORMONE SIGNALING PATHWAY(JAK2 STAT5)		10	-0.29	-0.66	0.890	0.940	1.000	3002	tags=20%, list=14%, signal=23%
369	INOH_HETEROTRIMERIC GPCR SIGNALING PATHWAY (THROUGH G ALPHA S ACS EPAC BRAF AND ERKCASCADE)		198	-0.16	-0.64	1.000	0.950	1.000	3304	tags=12%, list=15%, signal=14%
370	REACTOME_SHC_RELATED_EVENTS		10	-0.27	-0.62	0.909	0.957	1.000	5003	tags=40%, list=23%, signal=52%
371	BIOCARTA_CORTICOSTEROIDS AND CARDIOPROTECTION		25	-0.20	-0.59	0.979	0.968	1.000	1139	tags=8%, list=5%, signal=8%