Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_01_ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus_repos |
| Phenotype | phenotype_ATM_minus_versus_ATM_plus.cls#ATM_minus_versus_ATM_plus_repos |
| Upregulated in class | ATM_plus |
| GeneSet | NETPATH_TCR |
| Enrichment Score (ES) | -0.55647373 |
| Normalized Enrichment Score (NES) | -2.0706387 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.003589126 |
| FWER p-Value | 0.01 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PLCG1 | 1435149_at 1450360_at | 8 | 9.555 | 0.0373 | No | ||
| 2 | ACP1 | 1422716_a_at 1422717_at 1450720_at 1450721_at | 95 | 7.723 | 0.0637 | No | ||
| 3 | CEBPB | 1418901_at 1427844_a_at | 98 | 7.620 | 0.0936 | No | ||
| 4 | UNC119 | 1418123_at | 153 | 6.552 | 0.1170 | No | ||
| 5 | FYN | 1417558_at 1441647_at 1448765_at | 519 | 4.286 | 0.1171 | No | ||
| 6 | SHB | 1434153_at | 590 | 4.076 | 0.1300 | No | ||
| 7 | PIK3R2 | 1418463_at | 929 | 3.296 | 0.1275 | No | ||
| 8 | RASA1 | 1426476_at 1426477_at 1426478_at 1438998_at | 1500 | 2.593 | 0.1116 | No | ||
| 9 | TUBB2A | 1427838_at | 2114 | 2.070 | 0.0916 | No | ||
| 10 | NCL | 1415771_at 1415772_at 1415773_at 1442404_at 1456528_x_at | 2565 | 1.803 | 0.0781 | No | ||
| 11 | CDC42 | 1415724_a_at 1435807_at 1449574_a_at 1460708_s_at | 3187 | 1.571 | 0.0559 | No | ||
| 12 | SLA | 1420818_at 1420819_at 1441761_at 1447813_x_at | 3913 | 1.354 | 0.0280 | No | ||
| 13 | ABL1 | 1423999_at 1441291_at 1444134_at 1445153_at | 4702 | 1.192 | -0.0034 | No | ||
| 14 | PTPRC | 1422124_a_at 1440165_at | 4964 | 1.140 | -0.0109 | No | ||
| 15 | AKT1 | 1416657_at 1425711_a_at 1440950_at 1442759_at | 5518 | 1.047 | -0.0321 | No | ||
| 16 | DTX1 | 1425822_a_at 1458643_at | 5799 | 1.010 | -0.0410 | No | ||
| 17 | SKAP2 | 1418895_at 1457097_at 1460623_at | 6123 | 0.968 | -0.0519 | No | ||
| 18 | SKAP1 | 1437249_at 1440326_at 1440782_at 1441322_at 1441418_at 1441589_at 1456678_at | 6159 | 0.963 | -0.0498 | No | ||
| 19 | MAPK1 | 1419568_at 1426585_s_at 1442876_at 1453104_at | 6326 | 0.939 | -0.0537 | No | ||
| 20 | NFAM1 | 1425714_a_at 1428790_at | 8202 | 0.682 | -0.1369 | No | ||
| 21 | STK39 | 1419550_a_at 1419551_s_at 1431434_at 1445431_at | 8488 | 0.647 | -0.1474 | No | ||
| 22 | ARHGEF6 | 1429012_at 1442292_at | 9073 | 0.578 | -0.1719 | No | ||
| 23 | GIT2 | 1423391_at 1432160_at 1435925_at | 10456 | 0.422 | -0.2335 | No | ||
| 24 | CRK | 1416201_at 1425855_a_at 1436835_at 1448248_at 1460176_at | 10980 | 0.363 | -0.2560 | No | ||
| 25 | ENAH | 1421624_a_at 1424800_at 1424801_at 1431162_a_at 1442223_at 1446426_at 1458876_at | 11221 | 0.337 | -0.2657 | No | ||
| 26 | PTPN3 | 1443162_at 1455450_at | 11243 | 0.335 | -0.2654 | No | ||
| 27 | RIPK2 | 1421236_at 1450173_at | 11319 | 0.326 | -0.2675 | No | ||
| 28 | CD3E | 1422105_at 1445748_at | 11363 | 0.321 | -0.2682 | No | ||
| 29 | ZAP70 | 1422701_at 1439749_at 1440178_x_at | 11479 | 0.306 | -0.2723 | No | ||
| 30 | SYK | 1418261_at 1418262_at 1425797_a_at 1457239_at | 11646 | 0.289 | -0.2787 | No | ||
| 31 | HOMER3 | 1424859_at | 11824 | 0.269 | -0.2858 | No | ||
| 32 | DLG1 | 1415691_at 1445798_at 1450768_at 1459635_at | 11911 | 0.259 | -0.2887 | No | ||
| 33 | JAK3 | 1425750_a_at 1446515_at | 12294 | 0.222 | -0.3053 | No | ||
| 34 | YWHAQ | 1420828_s_at 1420829_a_at 1420830_x_at 1432842_s_at 1437608_x_at 1454378_at 1460590_s_at 1460621_x_at | 12338 | 0.217 | -0.3065 | No | ||
| 35 | CD2AP | 1420906_at 1420907_at 1420908_at 1460140_at | 12526 | 0.197 | -0.3143 | No | ||
| 36 | PTPN11 | 1421196_at 1427699_a_at 1451225_at | 12606 | 0.188 | -0.3171 | No | ||
| 37 | SRC | 1423240_at 1450918_s_at | 12634 | 0.185 | -0.3176 | No | ||
| 38 | JUN | 1417409_at 1448694_at | 13265 | 0.110 | -0.3461 | No | ||
| 39 | CBL | 1434829_at 1446608_at 1450457_at 1455886_at | 13354 | 0.098 | -0.3497 | No | ||
| 40 | RAP1A | 1424139_at | 13464 | 0.086 | -0.3544 | No | ||
| 41 | ARHGEF7 | 1424482_at 1449066_a_at | 14084 | 0.004 | -0.3827 | No | ||
| 42 | SHC1 | 1422853_at 1422854_at | 14924 | -0.125 | -0.4207 | No | ||
| 43 | PIK3R1 | 1425514_at 1425515_at 1438682_at 1444591_at 1451737_at | 15248 | -0.177 | -0.4348 | No | ||
| 44 | PTPRJ | 1425587_a_at 1425588_at 1427602_at 1427629_at 1443683_at 1455030_at | 15352 | -0.195 | -0.4387 | No | ||
| 45 | PAG1 | 1423002_at 1440033_at 1443319_at 1456403_at | 15557 | -0.231 | -0.4471 | No | ||
| 46 | DUSP3 | 1425608_at 1434472_at 1456769_at | 15687 | -0.257 | -0.4520 | No | ||
| 47 | LAT | 1460651_at | 16017 | -0.327 | -0.4658 | No | ||
| 48 | RAPGEF1 | 1421146_at 1427006_at 1441386_at | 16807 | -0.531 | -0.4999 | No | ||
| 49 | MAP2K1 | 1416351_at | 16935 | -0.572 | -0.5034 | No | ||
| 50 | CREB1 | 1421582_a_at 1421583_at 1423402_at 1428755_at 1452529_a_at 1452901_at | 17226 | -0.671 | -0.5141 | No | ||
| 51 | GRB2 | 1418508_a_at 1449111_a_at | 17468 | -0.764 | -0.5221 | No | ||
| 52 | LCP2 | 1418641_at 1418642_at | 17507 | -0.779 | -0.5208 | No | ||
| 53 | CTNNB1 | 1420811_a_at 1430533_a_at 1450008_a_at | 17618 | -0.827 | -0.5226 | No | ||
| 54 | TRAT1 | 1427532_at 1437561_at | 17860 | -0.932 | -0.5299 | No | ||
| 55 | NCK1 | 1421487_a_at 1424543_at 1447271_at | 17872 | -0.934 | -0.5268 | No | ||
| 56 | VAV3 | 1417122_at 1417123_at 1446795_at 1448600_s_at 1458630_at | 17899 | -0.949 | -0.5242 | No | ||
| 57 | ITK | 1417171_at 1430833_at 1452518_a_at 1456836_at 1457120_at | 18604 | -1.214 | -0.5517 | Yes | ||
| 58 | GAB2 | 1419829_a_at 1420785_at 1439786_at 1446860_at | 18641 | -1.233 | -0.5485 | Yes | ||
| 59 | SOS1 | 1421884_at 1421885_at 1421886_at | 18731 | -1.279 | -0.5475 | Yes | ||
| 60 | LIME1 | 1416869_x_at 1437589_x_at 1448500_a_at | 18834 | -1.342 | -0.5469 | Yes | ||
| 61 | STAT5B | 1422102_a_at 1422103_a_at | 18936 | -1.397 | -0.5460 | Yes | ||
| 62 | LCK | 1425396_a_at 1439145_at 1439146_s_at 1457917_at | 19071 | -1.481 | -0.5463 | Yes | ||
| 63 | SOS2 | 1452281_at | 19166 | -1.543 | -0.5446 | Yes | ||
| 64 | CARD11 | 1430257_at 1435996_at | 19280 | -1.617 | -0.5434 | Yes | ||
| 65 | KHDRBS1 | 1418628_at 1418630_at | 19320 | -1.644 | -0.5387 | Yes | ||
| 66 | PTPN22 | 1417995_at 1442820_at | 19360 | -1.671 | -0.5339 | Yes | ||
| 67 | NFATC2 | 1425901_at 1425990_a_at 1426031_a_at 1426032_at 1439205_at 1440426_at | 19581 | -1.851 | -0.5367 | Yes | ||
| 68 | PTPN12 | 1422045_a_at 1439705_at 1450478_a_at 1450479_x_at 1455105_at 1459459_at | 19648 | -1.912 | -0.5322 | Yes | ||
| 69 | BCL10 | 1418970_a_at 1418971_x_at 1418972_at 1443524_x_at | 19756 | -1.997 | -0.5292 | Yes | ||
| 70 | NEDD9 | 1422818_at 1437132_x_at 1447885_x_at 1450767_at | 19885 | -2.073 | -0.5269 | Yes | ||
| 71 | STAT5A | 1421469_a_at 1450259_a_at | 19892 | -2.079 | -0.5190 | Yes | ||
| 72 | PTK2B | 1434653_at 1442437_at 1442927_at | 19935 | -2.111 | -0.5126 | Yes | ||
| 73 | PRKD2 | 1434333_a_at 1434334_at 1436589_x_at 1437509_x_at 1456075_at | 19937 | -2.112 | -0.5043 | Yes | ||
| 74 | CBLB | 1437304_at 1455082_at 1458469_at | 19947 | -2.123 | -0.4964 | Yes | ||
| 75 | CD4 | 1419696_at 1427779_a_at | 20116 | -2.283 | -0.4951 | Yes | ||
| 76 | WAS | 1419631_at | 20171 | -2.335 | -0.4884 | Yes | ||
| 77 | FYB | 1452117_a_at | 20277 | -2.441 | -0.4836 | Yes | ||
| 78 | SH2D3C | 1415886_at | 20414 | -2.617 | -0.4795 | Yes | ||
| 79 | SLA2 | 1437504_at 1451492_at | 20471 | -2.687 | -0.4715 | Yes | ||
| 80 | CD3D | 1422828_at | 20479 | -2.698 | -0.4612 | Yes | ||
| 81 | CISH | 1448724_at | 20490 | -2.713 | -0.4510 | Yes | ||
| 82 | DBNL | 1460334_at | 20504 | -2.735 | -0.4408 | Yes | ||
| 83 | SH2D2A | 1449105_at | 20515 | -2.759 | -0.4304 | Yes | ||
| 84 | GRAP2 | 1456432_at | 20676 | -2.983 | -0.4260 | Yes | ||
| 85 | CD8A | 1440164_x_at 1440811_x_at | 20679 | -2.990 | -0.4143 | Yes | ||
| 86 | PTPN6 | 1456694_x_at 1460188_at | 20681 | -2.991 | -0.4025 | Yes | ||
| 87 | CRKL | 1421953_at 1421954_at 1425604_at 1436950_at | 20897 | -3.384 | -0.3991 | Yes | ||
| 88 | LAX1 | 1438687_at | 20919 | -3.427 | -0.3865 | Yes | ||
| 89 | FOS | 1423100_at | 20955 | -3.496 | -0.3744 | Yes | ||
| 90 | DNM2 | 1423629_at 1425135_a_at 1425136_x_at 1432004_a_at 1432005_at 1437938_x_at 1443150_at 1451057_x_at | 21058 | -3.701 | -0.3645 | Yes | ||
| 91 | VAV1 | 1422932_a_at | 21119 | -3.839 | -0.3521 | Yes | ||
| 92 | VASP | 1451097_at | 21184 | -3.984 | -0.3393 | Yes | ||
| 93 | ARHGDIB | 1426454_at | 21185 | -3.986 | -0.3236 | Yes | ||
| 94 | CREBBP | 1434633_at 1435224_at 1436983_at 1444856_at 1457641_at 1459804_at | 21224 | -4.102 | -0.3092 | Yes | ||
| 95 | CD3G | 1419178_at | 21259 | -4.191 | -0.2943 | Yes | ||
| 96 | SH3BP2 | 1448328_at | 21281 | -4.255 | -0.2785 | Yes | ||
| 97 | WASF2 | 1438683_at | 21307 | -4.361 | -0.2625 | Yes | ||
| 98 | DEF6 | 1452796_at | 21368 | -4.626 | -0.2470 | Yes | ||
| 99 | PSTPIP1 | 1424560_at | 21391 | -4.682 | -0.2296 | Yes | ||
| 100 | PRKCQ | 1426044_a_at | 21404 | -4.723 | -0.2115 | Yes | ||
| 101 | ABI1 | 1423177_a_at 1423178_at 1450890_a_at | 21462 | -4.955 | -0.1946 | Yes | ||
| 102 | GRAP | 1429387_at | 21598 | -5.745 | -0.1782 | Yes | ||
| 103 | SIT1 | 1418751_at | 21653 | -6.137 | -0.1565 | Yes | ||
| 104 | CD5 | 1418353_at | 21674 | -6.309 | -0.1325 | Yes | ||
| 105 | TXK | 1425785_a_at | 21684 | -6.391 | -0.1078 | Yes | ||
| 106 | DOCK2 | 1422808_s_at 1437282_at 1438334_at 1459382_at | 21756 | -7.077 | -0.0832 | Yes | ||
| 107 | CD247 | 1420716_at 1426079_at 1426396_at 1428059_at 1428060_at 1438392_at 1452539_a_at | 21823 | -7.633 | -0.0561 | Yes | ||
| 108 | EVL | 1434920_a_at 1440885_at 1445957_at 1450106_a_at 1456453_at 1458889_at | 21837 | -7.747 | -0.0262 | Yes | ||
| 109 | PTK2 | 1423059_at 1430827_a_at 1439198_at 1440082_at 1441475_at 1443384_at 1445137_at | 21846 | -7.797 | 0.0041 | Yes |
