RelationshipXref intact EBI-7524841 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7524841
db: intact

RelationshipXref refseq NP 014904 3
type: RelationshipXref
id: NP_014904.3
db: refseq

rpab3_yeast
type: Protein
evidence: Evidence be2ad302-137a-400e-9031-3f758baeac8c p 432350
entity reference: P20436
name: DNA-directed RNA polymerases I, II, and III subunit RPABC3
comment: psi-mi participant
data source: intact

med16_yeast
type: ProteinReference
sequence: MMLGEHLMSWSKTGIIAYSDSQSSNANICLTFLESINGINWRFHTPQKYVLHPQLHEVQYQESSSTLSTHSTTTSVNGSTTAGVGSTPNFGGNSNKSPPQFFYNISSIHWNNWFSLPGDMLAVCDELGNMTMLITGQRPDRATTYEKLTMVFQDNVYKIYNHVMPLKPVDKLKPMNIERKQTRKEYNTSILEFRWLTSSKSVIVSQFCAFDSSSNTYRSRAQQVPPYGVYHPPFIKYACLAIRKNGQIDFWYQFSNSKDHKKITLQLLDTSNQRFKDLQWLEFARITPMNDDQCMLITTYSKLSKNISFYKLHVNWNLNATKPNVLNDPSLKIQFILSTTLDPTDDEGHVLKLENLHVVSKSSIEKDPSPEILVLYNVCDTSKSLVKRYRLAPTQLSAEYLVILKPDLNIDRNNSTNQIFQSRRYNLRRHSDIVLDKKVTLITSEMFDAFVSFYFEDGTIESYNQNDWKLETERLISQSQLGKFKNIIASPLSAGFNYGKLPLPPSVEWMKVSPSMCGVIVKQYNKKWPQFYAAVQKNYADPEKDSINATALAFGYVKSLHKQISAEDLTIAAKTHILRISFLDRKRAKEFITTLLKSLYSFFNISPDAPKEIMDKIITSRPLQKIMLLQLELGSCFSQENIEEMARVILYLKNVLFAFNGVARNFHFAIEQISNNSNQQQNPKLFQTIFSKQDLIHSLIPVAKWFVKFITYLTQEILILINDPTNKEYTLVHGIFGAKMSRTLILSILNEIKKVTQIVAKFPETSYPILNESSTFLKLVLSESPVDFEKFETFLVDVNNKFIALCEQQPSQEREFSLLVKAEIPPEYAKVGDFLLQYANNAVISHANAAAVYFADTSGLKISNSEFFNPEIFHLLQPLEEGLIIDTDKLPIKNRTSKSFSKLLYDDVTCDKLSVSEISDGKLKRCSRCGSVTRAGNIISSDKTIVPTSIQTKRWPTMYTRLCICSGMLFEMDG
xref: RelationshipXref sgd S000005180
xref: RelationshipXref go GO 0070847
xref: RelationshipXref interpro IPR021665
xref: RelationshipXref go GO 0000122
xref: RelationshipXref go GO 0016592
xref: RelationshipXref mint P32259
xref: RelationshipXref go GO 0070202
xref: RelationshipXref go GO 0051123
xref: RelationshipXref uniprotkb D6W0V7 secondary-ac
xref: RelationshipXref dip DIP-1617N
xref: RelationshipXref go GO 0045944
xref: RelationshipXref go GO 0001102
xref: RelationshipXref intact EBI-17172 identity
xref: RelationshipXref refseq NP 014163 1
xref: UnificationXref uniprot knowledgebase P32259
organism: http://identifiers.org/taxonomy/559292
name: SWI4 suppressor protein 5
name: YGP1 expression regulatory protein 1
name: TSF3
name: SIN4
name: Global transcriptional regulator SIN4
name: SNF1 suppressor protein 4
name: Mediator of RNA polymerase II transcription subunit 16
name: GAL22
name: Transcriptional silencing factor 3
name: SSN4
name: SDI3
name: N1135
name: YNL236W
name: BEL2
name: Mediator complex subunit 16
name: RYE1
name: MED16
name: SSF5

eif3a_yeast
type: Protein
evidence: Evidence 5fcfb8c3-030d-479e-b602-f33a4efe1038 p 433386
entity reference: P38249
name: Eukaryotic translation initiation factor 3 subunit A
comment: psi-mi participant
data source: intact

rpn1-rpn8-7
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-1600 imex-primary
xref: RelationshipXref intact EBI-7544057 identity
xref: UnificationXref mint MINT-2211164
evidence: Evidence abd39eb4-67f4-4969-a20f-05025ed22fe5 IM-15332-1600 433913 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 0.648016612579672
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P38764 identity 1529029543360
participant: rpn8_yeast

Evidence 284399cf-8b91-4cb9-833d-740d46e2033b IM-15332-9204 431733 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm bfa978ba-ded4-4c7a-8e79-3029e4b7128a
type: ExperimentalForm
experimental feature: ModificationFeature e684a60e-5bf0-4321-a939-3fab53981fba 430980
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-10436 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-10436
db: imex

RelationshipXref rcsb pdb 4YTK
type: RelationshipXref
id: 4YTK
db: protein data bank

RelationshipXref refseq NP 012221 2
type: RelationshipXref
id: NP_012221.2
db: refseq

rpb3-rpb11
type: MolecularInteraction
xref: RelationshipXref intact EBI-7527277 identity
xref: UnificationXref mint MINT-2203731
xref: RelationshipXref imex IM-15332-1958 imex-primary
evidence: Evidence 790ee6ad-e8ed-4fce-9a91-7c9e223fbc40 IM-15332-1958 432273 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.99
comment: author-confidence:z-score: 5.97020420496146
data source: intact
participant: Protein uniprotkb P38902 identity 1529029542541
participant: Protein uniprotkb P16370 identity 1529029542540

RelationshipXref intact EBI-15826 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-15826
db: intact

Evidence 1b54e827-7863-4fcd-91e8-a387a0443881 IM-15332-7621 430437 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

tho2_yeast
type: Protein
evidence: Evidence d7e218cb-4124-4c7d-8e45-ad0889ca0ceb p 431190
entity reference: P53552
name: THO complex subunit 2
comment: psi-mi participant
data source: intact

tho2_yeast
type: Protein
evidence: Evidence 3eb7029e-cd75-4119-8bcf-573d67f59184 p 431187
entity reference: P53552
name: THO complex subunit 2
comment: psi-mi participant
data source: intact

tho2_yeast
type: Protein
evidence: Evidence 787fabd8-5ebb-433b-be78-efeb7b0a5979 p 431182
entity reference: P53552
name: THO complex subunit 2
comment: psi-mi participant
data source: intact

rpb8-rpb2-1
type: MolecularInteraction
xref: RelationshipXref intact EBI-7529483 identity
xref: RelationshipXref imex IM-15332-3987 imex-primary
xref: UnificationXref mint MINT-2204256
evidence: Evidence 9a87e7a5-d6fd-43e3-8c5d-e78ff0905525 IM-15332-3987 432389 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.531
comment: author-confidence:z-score: 4.45781722685975
comment: comment:mint
data source: intact
participant: Protein uniprotkb P08518 identity 1529029542598
participant: rpab3_yeast

tho2_yeast
type: Protein
evidence: Evidence e9633812-41a7-432c-84b6-566976ac1070 p 431178
entity reference: P53552
name: THO complex subunit 2
comment: psi-mi participant
data source: intact

tho2_yeast
type: Protein
evidence: Evidence b16ac0a2-551d-49d4-8373-5a70b1d4b5e9 p 431174
entity reference: P53552
name: THO complex subunit 2
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-10018 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-10018
db: imex

UnificationXref mint MINT-2210084
type: UnificationXref
id: MINT-2210084
db: mint

UnificationXref uniprot knowledgebase Q12102
type: UnificationXref
id: Q12102
db: uniprot knowledgebase

RelationshipXref intact EBI-7521747 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7521747
db: intact

RelationshipXref interpro IPR030475
type: RelationshipXref
id: IPR030475
db: interpro

RelationshipXref interpro IPR017334
type: RelationshipXref
id: IPR017334
db: interpro

tho2_yeast
type: Protein
evidence: Evidence a7212f19-ab8e-4b79-9597-1d6b475aca3f p 431170
entity reference: P53552
name: THO complex subunit 2
comment: psi-mi participant
data source: intact

ExperimentalForm c158bab1-3ac8-40f4-a5b8-288bd52b97a5
type: ExperimentalForm
experimental feature: ModificationFeature 6c52283a-03b1-4c04-9a13-7373a5809676 432604
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

tho2_yeast
type: Protein
evidence: Evidence d80c392e-ba25-4f91-aff4-e5cf3b73f8a8 p 431166
entity reference: P53552
name: THO complex subunit 2
comment: psi-mi participant
data source: intact

tho2_yeast
type: Protein
evidence: Evidence 78c2b467-d5d3-4be7-bb58-6774e9cbc540 p 431163
entity reference: P53552
name: THO complex subunit 2
comment: psi-mi participant
data source: intact

UnificationXref uniprot knowledgebase P36121
type: UnificationXref
id: P36121
db: uniprot knowledgebase

tho2_yeast
type: Protein
evidence: Evidence 333fcd11-d6a9-45e7-a8a2-a7a8ed7c3dd6 p 431158
entity reference: P53552
name: THO complex subunit 2
comment: psi-mi participant
data source: intact

tho2_yeast
type: Protein
evidence: Evidence 31bb5584-1bf8-4c64-8de9-3144f9441238 p 431154
entity reference: P53552
name: THO complex subunit 2
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2206970
type: UnificationXref
id: MINT-2206970
db: mint

RelationshipXref rcsb pdb 4ZGN
type: RelationshipXref
id: 4ZGN
db: protein data bank

ExperimentalForm 6eede2c8-5f23-41d1-b7d2-d5d13c0d4acc
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpab5_yeast
type: Protein
evidence: Evidence 4de683a1-7ff1-44e3-8ff4-4e8da09b0377 p 432107
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-1581 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1581
db: imex

rpb1_yeast
type: Protein
evidence: Evidence 2c2d2c53-8ad2-4fba-aa86-27d05fa27ddc p 432206
entity reference: P04050
name: DNA-directed RNA polymerase II subunit RPB1
comment: psi-mi participant
data source: intact

ExperimentalForm a54176ec-2e8e-4fab-94c2-475aa22cc2e0
type: ExperimentalForm
experimental feature: ModificationFeature 84705ade-0ea8-4ff7-93be-b42ab233d7d6 432199
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

tho2_yeast
type: Protein
evidence: Evidence 612a1028-5e67-4fee-b716-3104497fcd21 p 431150
entity reference: P53552
name: THO complex subunit 2
comment: psi-mi participant
data source: intact

tho2_yeast
type: Protein
evidence: Evidence 85a635ad-30ad-424d-9086-a795b5609b40 p 431147
entity reference: P53552
name: THO complex subunit 2
comment: psi-mi participant
data source: intact

rpn1-rpt1-20
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-1599 imex-primary
xref: UnificationXref mint MINT-2210948
xref: RelationshipXref intact EBI-7543100 identity
evidence: Evidence e25cca1c-bfa7-49fc-9ef0-a685a5ea1e01 IM-15332-1599 433865 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.93
comment: comment:homomint
comment: comment:mint
comment: author-confidence:z-score: 6.48436765612848
data source: intact
participant: prs7_yeast
participant: Protein uniprotkb P38764 identity 1529029543336

tho2_yeast
type: Protein
evidence: Evidence 0d854cae-e9a0-4cf7-85b2-9e7219ef7098 p 431143
entity reference: P53552
name: THO complex subunit 2
comment: psi-mi participant
data source: intact

rpc19-rpo31-4
type: MolecularInteraction
xref: RelationshipXref intact EBI-7532920 identity
xref: RelationshipXref imex IM-15332-9209 imex-primary
xref: UnificationXref mint MINT-2206069
evidence: Evidence 131e8544-c7f0-4bdd-b1a2-9c2af315a0df IM-15332-9209 432781 430156
interaction type: physical association
comment: author-confidence:z-score: 1.57763717123747
comment: comment:homomint
comment: author-confidence:reliability score: 0.631
comment: comment:mint
data source: intact
participant: Protein uniprotkb P04051 identity 1529029542795
participant: Protein uniprotkb P28000 identity 1529029542794

eif3a_yeast
type: Protein
evidence: Evidence b040d348-32c4-42a0-9935-2e88a1cb0a86 p 433499
entity reference: P38249
name: Eukaryotic translation initiation factor 3 subunit A
comment: psi-mi participant
data source: intact

ExperimentalForm 78c49bfb-27f4-4e6e-bf9b-602e0903725a
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref mint MINT-2210066
type: UnificationXref
id: MINT-2210066
db: mint

rpn7_yeast
type: Protein
evidence: Evidence 91e8743b-4417-4b6c-b328-b1a38448e07e p 433636
entity reference: Q06103
name: 26S proteasome regulatory subunit RPN7
comment: psi-mi participant
data source: intact

RelationshipXref interpro IPR030458
type: RelationshipXref
id: IPR030458
db: interpro

UnificationXref mint MINT-2210930
type: UnificationXref
id: MINT-2210930
db: mint

UnificationXref uniprot knowledgebase P36104
type: UnificationXref
id: P36104
db: uniprot knowledgebase

Evidence e98de9e9-c448-4d98-a677-a32f6bced106 IM-15332-6364 430461 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref mint MINT-2206952
type: UnificationXref
id: MINT-2206952
db: mint

RelationshipXref rcsb pdb 4Z1L
type: RelationshipXref
id: 4Z1L
db: protein data bank

ExperimentalForm 28f731df-08f0-4f97-9d53-32c6772a1e5a
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref dip DIP-1562N
type: RelationshipXref
id: DIP-1562N
db: database of interacting proteins

ExperimentalForm 63e44f5d-3591-436b-b26e-08a92b099586
type: ExperimentalForm
experimental feature: ModificationFeature 3cc07794-dc4b-49c2-9438-b962b8e7e57a 431960
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 65512b47-1eed-419e-8d00-a1b61c6166fd
type: ExperimentalForm
experimental feature: ModificationFeature 92f564de-e1ad-4fa0-869a-7888d72cc547 433680
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpab5_yeast
type: Protein
evidence: Evidence 53275fde-5176-4025-b764-85848434bcd3 p 432015
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

Evidence d4df62a8-0dae-4d2f-9d26-5dfcd083b1cf IM-15332-10855 432309 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref interpro IPR025995
type: RelationshipXref
id: IPR025995
db: interpro

RelationshipXref imex IM-15332-8420 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-8420
db: imex

RelationshipXref rcsb pdb 3TDD
type: RelationshipXref
id: 3TDD
db: protein data bank

RelationshipXref refseq NP 010669 1
type: RelationshipXref
id: NP_010669.1
db: refseq

spt5_yeast
type: Protein
evidence: Evidence 83c0ca69-c330-4766-9e54-e1e00864a166 p 432576
entity reference: P27692
name: Transcription elongation factor SPT5
comment: psi-mi participant
data source: intact

RelationshipXref uniprotkb D6VU12 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VU12
db: uniprot knowledgebase

RelationshipXref imex IM-15332-1591 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1591
db: imex

RelationshipXref intact EBI-7518391 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7518391
db: intact

RelationshipXref imex IM-15332-1218 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1218
db: imex

RelationshipXref go GO 0004128
type: RelationshipXref
id: GO:0004128
db: gene ontology

RelationshipXref rcsb pdb 1NIK
type: RelationshipXref
id: 1NIK
db: protein data bank

ExperimentalForm 36e52a76-b7dc-4708-8c9d-ba7d0e94b6d2
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref mint MINT-2206934
type: UnificationXref
id: MINT-2206934
db: mint

RelationshipXref intact EBI-36176 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-36176
db: intact

ExperimentalForm bb834452-6f77-47c7-b7fe-428f254d63f2
type: ExperimentalForm
experimental feature: ModificationFeature a5829ff8-0aae-462b-b5f4-da9b000afe41 430800
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 9d4bc706-12be-4ffc-88de-ce2516ccc8be
type: ExperimentalForm
experimental feature: ModificationFeature 9c22b832-13c8-445e-b725-a100d82ac6a5 433004
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

Evidence 6a221466-478d-4387-92bf-e82f79ea505b IM-15332-1587 432669 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpb7_yeast
type: Protein
evidence: Evidence 6ed13e3d-50a2-4e3b-bdd2-c2ec14d3702a p 432410
entity reference: rpb7_yeast
name: DNA-directed RNA polymerase II subunit RPB7
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-12498 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12498
db: imex

ExperimentalForm f5ff117a-4ef0-4e86-852d-28b4efa6b66b
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpc1_yeast
type: Protein
evidence: Evidence ce99ed6d-c98e-41c6-8edd-da853e786efc p 430556
entity reference: rpc1_yeast
name: DNA-directed RNA polymerase III subunit RPC1
comment: psi-mi participant
data source: intact

RelationshipXref sgd S000002165
type: RelationshipXref
id: S000002165
db: sgd

Evidence d13f5bcc-c90b-41c9-9847-a430d0cef14a IM-15332-1206 430645 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref rcsb pdb 3TBA
type: RelationshipXref
id: 3TBA
db: protein data bank

RelationshipXref reactome R-SCE-6798695
type: RelationshipXref
id: R-SCE-6798695
db: reactome

ExperimentalForm e101432d-bd4c-4869-be0c-2a5a0d0afbc5
type: ExperimentalForm
experimental feature: ModificationFeature b68c2916-3f83-4b9b-b0a2-266c7a8d4a92 431716
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 7755d528-66b5-4328-946c-49d893aa573a
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref rcsb pdb 3TB9
type: RelationshipXref
id: 3TB9
db: protein data bank

rpb9-tfg1-1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-1586 imex-primary
xref: RelationshipXref intact EBI-7530945 identity
xref: UnificationXref mint MINT-2204672
evidence: Evidence 11dd3212-f81d-46b9-981f-cf00895db223 IM-15332-1586 432477 430156
interaction type: physical association
comment: author-confidence:z-score: 2.61652260943079
comment: author-confidence:reliability score: 0.887
comment: comment:mint
data source: intact
participant: Protein uniprotkb P41895 identity 1529029542643
participant: Protein uniprotkb P27999 identity 1529029542642

Evidence fc970e8d-ce18-4f11-87c5-d6a40ad2c317 IM-15332-1591 432953 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

Evidence 1b9dc4e4-0fa5-44fd-bf73-56a75e110111 IM-15332-11637 431397 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref mint MINT-2206916
type: UnificationXref
id: MINT-2206916
db: mint

RelationshipXref imex IM-15332-12063 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12063
db: imex

Evidence 34ccda94-f3ef-46a3-9a11-602f607ce82c IM-15332-8827 433889 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

Evidence 82016fa6-5763-4a0e-897c-710b8a935c54 IM-15332-5176 432113 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ric1-rgp1-7
type: MolecularInteraction
xref: UnificationXref mint MINT-2198276
xref: RelationshipXref imex IM-15332-10431 imex-primary
xref: RelationshipXref intact EBI-7518631 identity
evidence: Evidence e07f1557-02ec-42ce-bf67-a750ca52d446 IM-15332-10431 431061 430156
interaction type: physical association
comment: author-confidence:z-score: 2.14497069555788
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P16664 identity 1529029541935
participant: Protein uniprotkb P40395 identity 1529029541934

RelationshipXref intact EBI-7518771 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7518771
db: intact

RelationshipXref imex IM-15332-3583 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-3583
db: imex

UnificationXref mint MINT-2202615
type: UnificationXref
id: MINT-2202615
db: mint

ssb2_yeast
type: Protein
evidence: Evidence ad8537db-a34c-42d3-b1da-b10cf6606aa0 p 433236
entity reference: P40150
name: Ribosome-associated molecular chaperone SSB2
comment: psi-mi participant
data source: intact

RelationshipXref interpro IPR016190
type: RelationshipXref
id: IPR016190
db: interpro

Evidence 88bf2397-2194-4ab7-a805-9b177087339c IM-15332-11634 431185 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref imex IM-15332-5600 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5600
db: imex

ExperimentalForm 3ca78b82-9249-415d-acd9-eb009c58fae9
type: ExperimentalForm
experimental feature: ModificationFeature 823ea158-6ba6-4896-82ef-4334f1171d8d 432875
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

Evidence 23ee4747-3008-4e0b-95ad-e18aa1c6b14e IM-15332-6791 433861 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm 784130d8-e260-43b9-afe5-e7ec93e37ad8
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ssb2_yeast
type: Protein
evidence: Evidence 90190814-13d8-448a-8265-af230d8b2d4a p 433230
entity reference: P40150
name: Ribosome-associated molecular chaperone SSB2
comment: psi-mi participant
data source: intact

ExperimentalForm 10e38710-1a28-4478-9519-9c395d66f1de
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref imex IM-15332-7208 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-7208
db: imex

rpc34-rpc82-2
type: MolecularInteraction
xref: RelationshipXref intact EBI-7534544 identity
xref: RelationshipXref imex IM-15332-3179 imex-primary
xref: UnificationXref mint MINT-2206790
evidence: Evidence 006cbad7-1df3-4158-aacf-0cb87cadf9d8 IM-15332-3179 432941 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.99
comment: author-confidence:z-score: 6.36795554985504
data source: intact
participant: rpc6_yeast
participant: Protein uniprotkb P32349 identity 1529029542874

ExperimentalForm 1b905241-9f36-494e-9a8c-93748aa43dbf
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref uniprot knowledgebase Q04062
type: UnificationXref
id: Q04062
db: uniprot knowledgebase

rco1-eaf3-7
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-1205 imex-primary
xref: UnificationXref mint MINT-2195303
xref: RelationshipXref intact EBI-7515190 identity
evidence: Evidence 8920c471-06c0-47fb-a663-dd0152702ef2 IM-15332-1205 430401 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.989
comment: author-confidence:z-score: 0.0727394815206485
comment: comment:mint
data source: intact
participant: Protein uniprotkb Q12432 identity 1529029541604
participant: rco1_yeast

RelationshipXref go GO 0043085
type: RelationshipXref
id: GO:0043085
db: gene ontology

UnificationXref mint MINT-2205547
type: UnificationXref
id: MINT-2205547
db: mint

UnificationXref mint MINT-2202633
type: UnificationXref
id: MINT-2202633
db: mint

rpb3-tfg1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-10855 imex-primary
xref: RelationshipXref intact EBI-7527826 identity
xref: UnificationXref mint MINT-2203893
evidence: Evidence d4df62a8-0dae-4d2f-9d26-5dfcd083b1cf IM-15332-10855 432309 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.989
comment: comment:mint
comment: author-confidence:z-score: 4.95905152944976
data source: intact
participant: Protein uniprotkb P16370 identity 1529029542559
participant: Protein uniprotkb P41895 identity 1529029542558

RelationshipXref uniprotkb D6VRK3 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VRK3
db: uniprot knowledgebase

RelationshipXref imex IM-15332-8022 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-8022
db: imex

Evidence 51d96d66-c3d3-47cc-bddb-62450016645e IM-15332-809 431617 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref go GO 2001208
type: RelationshipXref
id: GO:2001208
db: gene ontology

RelationshipXref intact EBI-7525448 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7525448
db: intact

ExperimentalForm a33fcdcf-7561-4ab3-8943-cc3bdee96355
type: ExperimentalForm
experimental feature: ModificationFeature ec03b91d-b7c0-4b79-9dd5-6c140c2c887a 431043
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-4771 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-4771
db: imex

RelationshipXref imex IM-15332-3999 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-3999
db: imex

Evidence fc189ee2-b45c-4591-807b-8a547f6f264c IM-15332-4784 432833 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref uniprotkb P38906 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: P38906
db: uniprot knowledgebase

ExperimentalForm 18620118-4393-469f-991e-6a6600a0d33d
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 525c3ec2-b4d1-4768-ab0f-035e189a0f39
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

sin3_yeast
type: Protein
evidence: Evidence 8bec736b-f5d7-44b6-b5d1-670f63906c0c p 430386
entity reference: sin3_yeast
name: Transcriptional regulatory protein SIN3
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2204183
type: UnificationXref
id: MINT-2204183
db: mint

UnificationXref mint MINT-2205529
type: UnificationXref
id: MINT-2205529
db: mint

ExperimentalForm c7c97d08-e530-4692-832e-61be84177803
type: ExperimentalForm
experimental feature: ModificationFeature 6d3c442c-1890-484b-b3a3-0b0a6ab9e817 432511
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

UnificationXref mint MINT-2202651
type: UnificationXref
id: MINT-2202651
db: mint

Evidence 2707bd8a-e6fd-4035-944d-b0179789f73c IM-15332-5165 430449 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref imex IM-15332-7200 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-7200
db: imex

RelationshipXref imex IM-15332-12490 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12490
db: imex

Evidence 10749082-b025-4d59-b053-4e40492bc170 IM-15332-5975 430953 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

sin3_yeast
type: Protein
evidence: Evidence e89578c6-82b9-44a2-bb01-60d0a61e43d2 p 430364
entity reference: sin3_yeast
name: Transcriptional regulatory protein SIN3
comment: psi-mi participant
data source: intact

sin3_yeast
type: Protein
evidence: Evidence fb5d9451-449b-4b4c-bf12-6d4bec4763fb p 430360
entity reference: sin3_yeast
name: Transcriptional regulatory protein SIN3
comment: psi-mi participant
data source: intact

sin3_yeast
type: Protein
evidence: Evidence 35a832c2-e946-4a74-b028-07a296a29625 p 430354
entity reference: sin3_yeast
name: Transcriptional regulatory protein SIN3
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 4X6A
type: RelationshipXref
id: 4X6A
db: protein data bank

ExperimentalForm fc666627-721a-45aa-adf5-195ea75555b9
type: ExperimentalForm
experimental feature: ModificationFeature e0d1b43e-0976-433f-bd5d-409279fb8d00 433727
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rco1_yeast
type: Protein
evidence: Evidence 645cca72-5bcd-4987-b834-237e08699bee p 430422
entity reference: Q04779
name: Transcriptional regulatory protein RCO1
comment: psi-mi participant
data source: intact

rco1_yeast
type: Protein
evidence: Evidence 457e9355-69d5-44fe-8b61-5387f647ed31 p 430418
entity reference: Q04779
name: Transcriptional regulatory protein RCO1
comment: psi-mi participant
data source: intact

rco1_yeast
type: Protein
evidence: Evidence d08586ac-d815-41f6-a3c6-990297c6b9b0 p 430414
entity reference: Q04779
name: Transcriptional regulatory protein RCO1
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2202669
type: UnificationXref
id: MINT-2202669
db: mint

RelationshipXref imex IM-15332-12489 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12489
db: imex

RelationshipXref intact EBI-18912 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-18912
db: intact

RelationshipXref intact EBI-7539686 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7539686
db: intact

RelationshipXref go GO 0032045
type: RelationshipXref
id: GO:0032045
db: gene ontology

RelationshipXref go GO 0032044
type: RelationshipXref
id: GO:0032044
db: gene ontology

RelationshipXref intact EBI-9038 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-9038
db: intact

RelationshipXref imex IM-15332-10427 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-10427
db: imex

RelationshipXref intact EBI-20070 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-20070
db: intact

RelationshipXref go GO 0032040
type: RelationshipXref
id: GO:0032040
db: gene ontology

UnificationXref mint MINT-2204165
type: UnificationXref
id: MINT-2204165
db: mint

RelationshipXref mint P09938
type: RelationshipXref
id: P09938
db: mint

rco1_yeast
type: Protein
evidence: Evidence d8ca4880-d32f-4f99-b256-7e1efdeddd12 p 430410
entity reference: Q04779
name: Transcriptional regulatory protein RCO1
comment: psi-mi participant
data source: intact

rco1_yeast
type: Protein
evidence: Evidence 5d0bba03-76ba-4608-8327-301e7603c62c p 430407
entity reference: Q04779
name: Transcriptional regulatory protein RCO1
comment: psi-mi participant
data source: intact

rco1_yeast
type: Protein
evidence: Evidence 9a6e37f4-121f-48f9-82f0-bb5b04b1d9d6 p 430403
entity reference: Q04779
name: Transcriptional regulatory protein RCO1
comment: psi-mi participant
data source: intact

rco1_yeast
type: Protein
evidence: Evidence 17f93f88-eedd-4325-bae9-7c6aec3674fa p 430399
entity reference: Q04779
name: Transcriptional regulatory protein RCO1
comment: psi-mi participant
data source: intact

ExperimentalForm 7b25b7da-95ff-45f8-95d4-24162b2d9dc7
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ret2-cop1-8
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-3579 imex-primary
xref: UnificationXref mint MINT-2196528
xref: RelationshipXref intact EBI-7516572 identity
evidence: Evidence c7b0914b-a405-4b02-8773-9b049b184b92 IM-15332-3579 430673 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 4.43011444103364
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P43621 identity 1529029541740
participant: Protein uniprotkb P53622 identity 1529029541741

ExperimentalForm 91f80a34-99c8-4ee6-a709-9584d9cf36b7
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpab5_yeast
type: Protein
evidence: Evidence 2445e6b1-75b6-463c-b7d7-36af21d46d80 p 431902
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

ExperimentalForm 63ed332d-51ea-44fa-b4d7-14b6a536a29e
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

Evidence 49ccfd63-0cc7-43b5-a4df-7e696783e8f2 IM-15332-3159 431013 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

Evidence 475e3a5c-8cbb-453b-ac91-d1c73cf8e499 IM-15332-3591 432861 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref uniprot knowledgebase P38886
type: UnificationXref
id: P38886
db: uniprot knowledgebase

RelationshipXref imex IM-15332-8406 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-8406
db: imex

ExperimentalForm 89e8ab30-73c7-43d4-a996-2113273e8300
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref refseq NP 010141 1
type: RelationshipXref
id: NP_010141.1
db: refseq

RelationshipXref intact EBI-7521202 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7521202
db: intact

rpab5_yeast
type: Protein
evidence: Evidence b6ee9814-e55c-444c-9f51-8d4e184017bd p 431918
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

ExperimentalForm d79e9085-dde2-4432-9fde-50ffa8140f3a
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm c0eb9d3a-481d-426c-9377-e6db8fb04d9b
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref interpro IPR023194
type: RelationshipXref
id: IPR023194
db: interpro

UnificationXref mint MINT-2204147
type: UnificationXref
id: MINT-2204147
db: mint

RelationshipXref imex IM-15332-12873 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12873
db: imex

ssn8_yeast
type: ProteinReference
sequence: MSGSFWTSTQRHHWQYTKASLAKERQKLWLLECQLFPQGLNIVMDSKQNGIEQSITKNIPITHRDLHYDKDYNLRIYCYFLIMKLGRRLNIRQYALATAHIYLSRFLIKASVREINLYMLVTTCVYLACKVEECPQYIRTLVSEARTLWPEFIPPDPTKVTEFEFYLLEELESYLIVHHPYQSLKQIVQVLKQPPFQITLSSDDLQNCWSLINDSYINDVHLLYPPHIIAVACLFITISIHGKPTKGSSLASAASEAIRDPKNSSSPVQIAFNRFMAESLVDLEEVMDTIQEQITLYDHWDKYHEQWIKFLLHTLYLRPASAI
xref: RelationshipXref reactome R-SCE-674695
xref: RelationshipXref mint P47821
xref: RelationshipXref go GO 0000307
xref: RelationshipXref go GO 1901409
xref: RelationshipXref interpro IPR036915
xref: RelationshipXref go GO 0000122
xref: RelationshipXref go GO 0010673
xref: RelationshipXref go GO 0000979
xref: RelationshipXref go GO 0045944
xref: RelationshipXref sgd S000004970
xref: UnificationXref uniprot knowledgebase P47821
xref: RelationshipXref go GO 0045737
xref: RelationshipXref interpro IPR013763
xref: RelationshipXref intact EBI-20078 identity
xref: RelationshipXref interpro IPR006671
xref: RelationshipXref interpro IPR028367
xref: RelationshipXref go GO 0016538
xref: RelationshipXref dip DIP-2007N
xref: RelationshipXref refseq NP 014373 3
xref: RelationshipXref go GO 0006351
xref: RelationshipXref go GO 0016592
xref: RelationshipXref uniprotkb D6W1F3 secondary-ac
xref: RelationshipXref go GO 0000411
xref: RelationshipXref reactome R-SCE-6796648
organism: http://identifiers.org/taxonomy/559292
name: RNA polymerase II holoenzyme cyclin-like subunit
name: N2805
name: GIG3
name: UME3
name: NUT9
name: YNL025C
name: SRB11
name: SSN8
name: Suppressor of RNA polymerase B 11

ExperimentalForm ac3e6eae-4908-483f-945f-d079ee766130
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7523938 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7523938
db: intact

RelationshipXref sgd S000001948
type: RelationshipXref
id: S000001948
db: sgd

rgr1-med4-1
type: MolecularInteraction
xref: RelationshipXref intact EBI-7518376 identity
xref: RelationshipXref imex IM-15332-3159 imex-primary
xref: UnificationXref mint MINT-2198060
evidence: Evidence 49ccfd63-0cc7-43b5-a4df-7e696783e8f2 IM-15332-3159 431013 430156
interaction type: physical association
comment: author-confidence:z-score: 7.8997459607277
comment: comment:mint
comment: author-confidence:reliability score: 0.681
data source: intact
participant: Protein uniprotkb Q12343 identity 1529029541910
participant: Protein uniprotkb P19263 identity 1529029541911

RelationshipXref sgd S000001944
type: RelationshipXref
id: S000001944
db: sgd

RelationshipXref go GO 0000932
type: RelationshipXref
id: GO:0000932
db: gene ontology

RelationshipXref imex IM-15332-2341 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-2341
db: imex

rpab5_yeast
type: Protein
evidence: Evidence e147b8d0-8e4e-4f79-874d-aa20ff1baf28 p 431950
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

rpn1-rpn5-7
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-4408 imex-primary
xref: UnificationXref mint MINT-2210084
xref: RelationshipXref intact EBI-7541519 identity
evidence: Evidence 7901981a-8bd6-40ff-94e8-d07f393145b8 IM-15332-4408 433673 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 1.89099179433043
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: rpn5_yeast
participant: Protein uniprotkb P38764 identity 1529029543240

ExperimentalForm 7ae46b54-dace-43b6-8829-759ae4eaff5f
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref uniprot knowledgebase P38741
type: UnificationXref
id: P38741
db: uniprot knowledgebase

RelationshipXref imex IM-15332-7626 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-7626
db: imex

UnificationXref mint MINT-2204129
type: UnificationXref
id: MINT-2204129
db: mint

rpab5_yeast
type: Protein
evidence: Evidence df0d828b-3aea-4498-bc8d-8876c105f59d p 431971
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

ExperimentalForm bcbd8a4d-00ac-4369-b7c2-c2158d410984
type: ExperimentalForm
experimental feature: ModificationFeature 4cfdad61-e632-4e0e-8457-4a9236ba14a6 431272
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref go GO 0006897
type: RelationshipXref
id: GO:0006897
db: gene ontology

UnificationXref uniprot knowledgebase P38859
type: UnificationXref
id: P38859
db: uniprot knowledgebase

RelationshipXref go GO 0007114
type: RelationshipXref
id: GO:0007114
db: gene ontology

RelationshipXref go GO 0006891
type: RelationshipXref
id: GO:0006891
db: gene ontology

RelationshipXref uniprotkb D6VRY1 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VRY1
db: uniprot knowledgebase

RelationshipXref intact EBI-15790 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-15790
db: intact

RelationshipXref imex IM-15332-4781 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-4781
db: imex

UnificationXref mint MINT-2195411
type: UnificationXref
id: MINT-2195411
db: mint

RelationshipXref imex IM-15332-12883 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12883
db: imex

RelationshipXref intact EBI-7523536 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7523536
db: intact

rpab5_yeast
type: Protein
evidence: Evidence 30259293-5506-4fdc-89ae-4dc38be7a9df p 431991
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

RelationshipXref interpro IPR023160
type: RelationshipXref
id: IPR023160
db: interpro

UnificationXref mint MINT-2202345
type: UnificationXref
id: MINT-2202345
db: mint

RelationshipXref go GO 0006888
type: RelationshipXref
id: GO:0006888
db: gene ontology

RelationshipXref go GO 0006887
type: RelationshipXref
id: GO:0006887
db: gene ontology

RelationshipXref go GO 0006886
type: RelationshipXref
id: GO:0006886
db: gene ontology

Evidence fcd05c79-3707-4f1a-8eef-04984f7c35b8 IM-15332-7633 431565 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref mint Q03010
type: RelationshipXref
id: Q03010
db: mint

ExperimentalForm 6307c90e-f5f2-4de7-b1a6-29f2f66675af
type: ExperimentalForm
experimental feature: ModificationFeature 84e86be6-3f08-44ce-b37d-884803fd1549 433839
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref dip DIP-1566N
type: RelationshipXref
id: DIP-1566N
db: database of interacting proteins

ExperimentalForm d845bcc0-bdca-4695-abe7-3d699cd23beb
type: ExperimentalForm
experimental feature: ModificationFeature 36e62f5b-a5a0-4edd-a630-3ae736d9460e 430632
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-1579 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1579
db: imex

Evidence 3a070b0c-0904-4303-898b-856b5d7f6076 IM-15332-1217 432281 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref molecular interactions ontology MI 0676
type: UnificationXref
id: MI:0676
db: molecular interactions ontology

RelationshipXref rcsb pdb 4WNN
type: RelationshipXref
id: 4WNN
db: protein data bank

RelationshipXref interpro IPR023152
type: RelationshipXref
id: IPR023152
db: interpro

RelationshipXref go GO 0006873
type: RelationshipXref
id: GO:0006873
db: gene ontology

rpa43-rpa190-1
type: MolecularInteraction
xref: RelationshipXref intact EBI-7523862 identity
xref: RelationshipXref imex IM-15332-12878 imex-primary
xref: UnificationXref mint MINT-2201804
evidence: Evidence 810f1317-37fc-4e9d-ac69-e5fb3f4255cc IM-15332-12878 431845 430156
interaction type: physical association
comment: author-confidence:z-score: 2.12631977398049
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: rpa1_yeast
participant: rpa43_yeast

rpb9-rpb3-1
type: MolecularInteraction
xref: UnificationXref mint MINT-2204852
xref: RelationshipXref imex IM-15332-5180 imex-primary
xref: RelationshipXref intact EBI-7531176 identity
evidence: Evidence c2cde2dc-5fec-40d3-b650-66df8e343172 IM-15332-5180 432517 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 7.24569923342546
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P27999 identity 1529029542662
participant: Protein uniprotkb P16370 identity 1529029542663

RelationshipXref intact EBI-7518647 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7518647
db: intact

RelationshipXref sgd S000001900
type: RelationshipXref
id: S000001900
db: sgd

UnificationXref molecular interactions ontology MI 0662
type: UnificationXref
id: MI:0662
db: molecular interactions ontology

RelationshipXref go GO 0016559
type: RelationshipXref
id: GO:0016559
db: gene ontology

ExperimentalForm a76c1a45-8c10-466a-98ab-868084f285c8
type: ExperimentalForm
experimental feature: ModificationFeature 80914f56-6bfa-44fa-ac5e-c8d8e3eb0983 432783
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref rcsb pdb 3E9F
type: RelationshipXref
id: 3E9F
db: protein data bank

RelationshipXref intact EBI-7542563 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7542563
db: intact

ExperimentalForm 407d1e75-ea54-4405-9827-f911a846a684
type: ExperimentalForm
experimental feature: ModificationFeature 3e969156-0b6d-4c28-895d-ac8c6213b8d9 433404
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm e1443b74-5788-4a15-b78e-a4dacd9603bb
type: ExperimentalForm
experimental feature: ModificationFeature 5227b1e4-527a-4b9b-b90f-d9e9373e57a9 432340
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref mint P08518
type: RelationshipXref
id: P08518
db: mint

RelationshipXref intact EBI-7532174 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7532174
db: intact

RelationshipXref interpro IPR023139
type: RelationshipXref
id: IPR023139
db: interpro

rpg1-tif5-5
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-6790 imex-primary
xref: RelationshipXref intact EBI-7539864 identity
xref: UnificationXref mint MINT-2209436
evidence: Evidence 35f81371-1e9f-4c0e-b83a-e85cb9084d5e IM-15332-6790 433529 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 9.5057952708461
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P38249 identity 1529029543168
participant: Protein uniprotkb P38431 identity 1529029543169

RelationshipXref imex IM-15332-1963 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1963
db: imex

RelationshipXref cygd YDR418w
type: RelationshipXref
id: YDR418w
db: cygd

ExperimentalForm 4643799f-2804-4c6f-bab7-8a796bfe8cd6
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 88c86b04-07d9-4086-b799-3e86c727e8e9
type: ExperimentalForm
experimental feature: ModificationFeature 70cb97be-b7d6-4ce0-8a65-19a1d677bab8 430428
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7518547 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7518547
db: intact

eif3b_yeast
type: Protein
evidence: Evidence 0737bb3c-a801-457a-8536-78b4c2b88f84 p 433434
entity reference: P06103
name: Eukaryotic translation initiation factor 3 subunit B
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7521602 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7521602
db: intact

RelationshipXref reactome R-SCE-8876725
type: RelationshipXref
id: R-SCE-8876725
db: reactome

Evidence 4eb63598-33b2-47f1-8c7e-9e0562df6fdb IM-15332-5978 431613 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref intact EBI-7522681 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7522681
db: intact

RelationshipXref interpro IPR002464
type: RelationshipXref
id: IPR002464
db: interpro

RelationshipXref go GO 0007163
type: RelationshipXref
id: GO:0007163
db: gene ontology

rpc40-rpa34
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-3995 imex-primary
xref: UnificationXref mint MINT-2207312
xref: RelationshipXref intact EBI-7535535 identity
evidence: Evidence a330939e-89e1-4613-acbb-cff26d763957 IM-15332-3995 433057 430156
interaction type: physical association
comment: author-confidence:z-score: 0.0727753807777444
comment: author-confidence:reliability score: 0.976
comment: comment:mint
data source: intact
participant: Protein uniprotkb P07703 identity 1529029542933
participant: Protein uniprotkb P47006 identity 1529029542932

RelationshipXref imex IM-15332-11255 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-11255
db: imex

mnl1_yeast
type: Protein
evidence: Evidence d3c04658-05e6-4187-9eae-59ea4244d40d p 430812
entity reference: mnl1_yeast
name: ER degradation-enhancing alpha-mannosidase-like protein 1
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7516165 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7516165
db: intact

rpb3-rpb2-3
type: MolecularInteraction
xref: RelationshipXref intact EBI-7527463 identity
xref: RelationshipXref imex IM-15332-5590 imex-primary
xref: UnificationXref mint MINT-2203785
evidence: Evidence 916cae2e-862c-49dd-a2ff-fcd162df968b IM-15332-5590 432285 430156
interaction type: physical association
comment: author-confidence:z-score: 1.27651338805604
comment: comment:mint
comment: author-confidence:reliability score: 0.97
data source: intact
participant: Protein uniprotkb P16370 identity 1529029542546
participant: Protein uniprotkb P08518 identity 1529029542547

pp12_yeast
type: Protein
evidence: Evidence 27097c85-617e-454b-8bc1-01c9d2155aa7 p 430474
entity reference: pp12_yeast
name: Serine/threonine-protein phosphatase PP1-2
comment: psi-mi participant
data source: intact

mnl1_yeast
type: Protein
evidence: Evidence 3acf36b9-2bbe-445e-81eb-a836cc2a6727 p 430796
entity reference: mnl1_yeast
name: ER degradation-enhancing alpha-mannosidase-like protein 1
comment: psi-mi participant
data source: intact

RelationshipXref reactome REACT 314339
type: RelationshipXref
id: REACT_314339
db: reactome

RelationshipXref imex IM-15332-5190 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5190
db: imex

tho2-gbp2-1
type: MolecularInteraction
xref: UnificationXref mint MINT-2198780
xref: RelationshipXref imex IM-15332-6369 imex-primary
xref: RelationshipXref intact EBI-7519188 identity
evidence: Evidence ba22c148-a7fe-4ec7-8137-b00fa20efb3d IM-15332-6369 431173 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.815
comment: author-confidence:z-score: 4.07659618638403
comment: comment:mint
data source: intact
participant: Protein uniprotkb P25555 identity 1529029541991
participant: tho2_yeast

RelationshipXref imex IM-15332-10453 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-10453
db: imex

RelationshipXref go GO 0090630
type: RelationshipXref
id: GO:0090630
db: gene ontology

RelationshipXref interpro IPR012341
type: RelationshipXref
id: IPR012341
db: interpro

RelationshipXref intact EBI-7521217 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7521217
db: intact

RelationshipXref imex IM-15332-11257 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-11257
db: imex

ExperimentalForm 27e1beec-5726-4fad-93c2-fadf72a3c4bc
type: ExperimentalForm
experimental feature: ModificationFeature e3283c82-fb69-4009-9b58-c39920bb15d6 432691
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

tho2-thp2-1
type: MolecularInteraction
xref: UnificationXref mint MINT-2199356
xref: RelationshipXref imex IM-15332-5977 imex-primary
xref: RelationshipXref intact EBI-7520259 identity
evidence: Evidence f4684bae-c311-42e1-8180-597e1cdef732 IM-15332-5977 431301 430156
interaction type: physical association
comment: author-confidence:z-score: 1.51347869441377
comment: comment:mint
comment: author-confidence:reliability score: 0.495
data source: intact
participant: Protein uniprotkb O13539 identity 1529029542055
participant: tho2_yeast

rpd3-sin3-2
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-10037 imex-primary
xref: RelationshipXref intact EBI-7538118 identity
xref: UnificationXref mint MINT-2208482
evidence: Evidence 834b7d4f-052c-4f2d-8655-7b243fc178df IM-15332-10037 433317 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 2.38938245325345
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: rpd3_yeast
participant: Protein uniprotkb P22579 identity 1529029543062

ExperimentalForm b7f1ee10-e96a-48e3-9113-c7b2a4033fe8
type: ExperimentalForm
experimental feature: ModificationFeature d48decbc-fee7-415d-bd67-3a2a76fe04bc 432907
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7541075 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7541075
db: intact

RelationshipXref uniprotkb D3DLX9 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D3DLX9
db: uniprot knowledgebase

UnificationXref uniprot knowledgebase P38782
type: UnificationXref
id: P38782
db: uniprot knowledgebase

Evidence 84ed2911-a4b3-46c4-9452-9a9d001f223a IM-15332-413 433741 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref interpro IPR001093
type: RelationshipXref
id: IPR001093
db: interpro

Evidence 80ce039d-8114-4cb7-88e9-d1c75ef56013 IM-15332-3181 433461 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm df0e6918-4586-4c42-81ca-6c3782987f8a
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rfa2-dna2-5
type: MolecularInteraction
xref: UnificationXref mint MINT-2197159
xref: RelationshipXref intact EBI-7517231 identity
xref: RelationshipXref imex IM-15332-5169 imex-primary
evidence: Evidence a0b57758-637c-42c8-97d2-dbf82d74def5 IM-15332-5169 430813 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 0.125175457397873
comment: author-confidence:reliability score: 0.771
comment: comment:mint
data source: intact
participant: Protein uniprotkb P26754 identity 1529029541811
participant: dna2_yeast

rpg1-prt1-4
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-10040 imex-primary
xref: UnificationXref mint MINT-2209076
xref: RelationshipXref intact EBI-7539052 identity
evidence: Evidence e6af458e-0c49-4154-9949-d32f634cfa02 IM-15332-10040 433449 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.99
comment: author-confidence:z-score: 2.64425747098545
data source: intact
participant: eif3b_yeast
participant: Protein uniprotkb P38249 identity 1529029543128

rpb7_yeast
type: ProteinReference
sequence: MFFIKDLSLNITLHPSFFGPRMKQYLKTKLLEEVEGSCTGKFGYILCVLDYDNIDIQRGRILPTDGSAEFNVKYRAVVFKPFKGEVVDGTVVSCSQHGFEVQVGPMKVFVTKHLMPQDLTFNAGSNPPSYQSSEDVITIKSRIRVKIEGCISQVSSIHAIGSIKEDYLGAI
xref: RelationshipXref reactome R-SCE-6796648
xref: RelationshipXref rcsb pdb 4BXZ
xref: RelationshipXref rcsb pdb 4BXX
xref: RelationshipXref go GO 0060213
xref: RelationshipXref rcsb pdb 4BY7
xref: RelationshipXref rcsb pdb 4BY1
xref: RelationshipXref rcsb pdb 5SVA
xref: RelationshipXref go GO 0005737
xref: RelationshipXref reactome R-SCE-76042
xref: RelationshipXref go GO 0003697
xref: RelationshipXref interpro IPR012340
xref: RelationshipXref rcsb pdb 3HOX
xref: RelationshipXref rcsb pdb 3HOZ
xref: RelationshipXref rcsb pdb 1Y77
xref: RelationshipXref go GO 0045948
xref: RelationshipXref interpro IPR005576
xref: RelationshipXref interpro IPR022967
xref: RelationshipXref sgd S000002812
xref: RelationshipXref rcsb pdb 3QT1
xref: RelationshipXref reactome R-SCE-113418
xref: RelationshipXref reactome R-SCE-75953
xref: UnificationXref uniprot knowledgebase P34087
xref: RelationshipXref rcsb pdb 5FMF
xref: RelationshipXref go GO 0003727
xref: RelationshipXref rcsb pdb 5FYW
xref: RelationshipXref rcsb pdb 5FZ5
xref: RelationshipXref go GO 0003899
xref: RelationshipXref rcsb pdb 3HOY
xref: RelationshipXref go GO 0005665
xref: RelationshipXref rcsb pdb 3HOW
xref: RelationshipXref rcsb pdb 3HOV
xref: RelationshipXref rcsb pdb 3HOU
xref: RelationshipXref intact EBI-15790 identity
xref: RelationshipXref reactome R-SCE-6782210
xref: RelationshipXref rcsb pdb 4A3M
xref: RelationshipXref rcsb pdb 4A3L
xref: RelationshipXref rcsb pdb 4A3K
xref: RelationshipXref rcsb pdb 3K1F
xref: RelationshipXref rcsb pdb 4A3I
xref: RelationshipXref rcsb pdb 5C4X
xref: RelationshipXref rcsb pdb 4A3G
xref: RelationshipXref rcsb pdb 4A3F
xref: RelationshipXref rcsb pdb 4A3E
xref: RelationshipXref rcsb pdb 4A3D
xref: RelationshipXref rcsb pdb 4A3C
xref: RelationshipXref rcsb pdb 4A3B
xref: RelationshipXref go GO 0000932
xref: RelationshipXref rcsb pdb 5C4A
xref: RelationshipXref rcsb pdb 3FKI
xref: RelationshipXref go GO 0001172
xref: RelationshipXref rcsb pdb 5IP9
xref: RelationshipXref go GO 0006367
xref: RelationshipXref go GO 0006366
xref: RelationshipXref rcsb pdb 5C44
xref: RelationshipXref go GO 0005634
xref: RelationshipXref rcsb pdb 1NT9
xref: RelationshipXref rcsb pdb 5C3E
xref: RelationshipXref uniprotkb D6VT36 secondary-ac
xref: RelationshipXref rcsb pdb 1Y1Y
xref: RelationshipXref rcsb pdb 1Y1W
xref: RelationshipXref rcsb pdb 1Y1V
xref: RelationshipXref rcsb pdb 5OT2
xref: RelationshipXref reactome R-SCE-674695
xref: RelationshipXref reactome R-SCE-72165
xref: RelationshipXref rcsb pdb 5U5Q
xref: RelationshipXref rcsb pdb 1Y14
xref: RelationshipXref reactome R-SCE-6782135
xref: RelationshipXref rcsb pdb 2JA8
xref: RelationshipXref rcsb pdb 2JA7
xref: RelationshipXref rcsb pdb 2JA6
xref: RelationshipXref rcsb pdb 2JA5
xref: RelationshipXref rcsb pdb 2B8K
xref: RelationshipXref rcsb pdb 3H3V
xref: RelationshipXref rcsb pdb 4V1O
xref: RelationshipXref rcsb pdb 4V1N
xref: RelationshipXref interpro IPR003029
xref: RelationshipXref mint P34087
xref: RelationshipXref reactome R-SCE-77075

ExperimentalForm bd050587-7e0d-4fa6-9cc3-4ba1852cdaeb
type: ExperimentalForm
experimental feature: ModificationFeature 3611c145-149f-494b-a8c7-09c31780f90c 432220
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-11641 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-11641
db: imex

RelationshipXref mint P50947
type: RelationshipXref
id: P50947
db: mint

RelationshipXref intact EBI-7516472 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7516472
db: intact

rpa43_yeast
type: Protein
evidence: Evidence 557800e5-be0e-44d9-806d-abd2ac8689bb p 433170
entity reference: P46669
name: DNA-directed RNA polymerase I subunit RPA43
comment: psi-mi participant
data source: intact

rpa43_yeast
type: Protein
evidence: Evidence ef2afdc0-af0a-4b51-9c51-6cd5533da82b p 433160
entity reference: P46669
name: DNA-directed RNA polymerase I subunit RPA43
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-8021 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-8021
db: imex

Evidence 3d44f0e1-7c7d-4422-9545-8f687fd8dc79 IM-15332-9203 431633 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rim4_yeast
type: ProteinReference
sequence: MKTEISTADSLRDPPSNGLKADSELVIREDIDQFLPSEVSSLGSDHQNDGEDSDTDSDNFLQDPEDDVDEESTGRGTVTTTSTSTESRGRPSSCIFVASLAAALSDDELCLSVTENFKKYGDLARVKVLRDNANRPYAFVQYNNDHDAKHALIRAQGTLLNGRRLRCEPAKVNRTLYLKNQQSIDFNEISQICEKFGGLEQIVPDRTDNQYTRRYTYPISSANSWFVQFVYRDDAIRAYANLRTDPNWIIEWAQNINVPKNYNLLHKSKFKSSKYHQNNGIINNDGSNNNDNNNSNNNNREDSRRNGDVIEEECGHVHGSDSEEKLTSDGIYDDEDKDSEITIDKRSIFVGQLDKETTREELNRRFSTHGKIQDINLIFKPTNIFAFIKYETEEAAAAALESENHAIFLNKTMHVQYKEVGGRHNRKFSGKNGGSNFNHHQFFSTRSGKTFTGPELNLAPPPINMYRKMSGGSQQESETMMPYMPMGPMPMGPPPPNAASLSDFDMFPPSYSTFMKGMMPLRRKSMPNSWSSPSSKSVNSENESVNGGDENSELPSEIPESSGRYNAANSFTTYNNSSAGNSNNNNNNNNSNSNKSQYKKRYARRSSYGYNEVPPKPYYFQPYYYHPMQYHMGPMGPLHPSQGSAGNHHPYMMVYPMSPPPPSGLDGSMIPPPINVSQSHAANHGSTHVHANEFISNDTGDINEDNKAYSLDY
xref: RelationshipXref dip DIP-5673N
xref: RelationshipXref go GO 0003723
xref: RelationshipXref interpro IPR012677
xref: RelationshipXref go GO 0030435
xref: RelationshipXref refseq NP 011839 1
xref: RelationshipXref uniprotkb E9P8V3 secondary-ac
xref: RelationshipXref uniprotkb D3DKU4 secondary-ac
xref: RelationshipXref go GO 0006279
xref: UnificationXref uniprot knowledgebase P38741
xref: RelationshipXref interpro IPR034352
xref: RelationshipXref intact EBI-24341 identity
xref: RelationshipXref interpro IPR000504
xref: RelationshipXref interpro IPR003954
xref: RelationshipXref go GO 0005634
xref: RelationshipXref interpro IPR035979
xref: RelationshipXref go GO 0007131
xref: RelationshipXref go GO 0051321
xref: RelationshipXref mint P38741
xref: RelationshipXref sgd S000001016
organism: http://identifiers.org/taxonomy/559292
name: YHL024W
name: Regulator of IME2 protein 4
name: RIM4
name: Meiotic activator RIM4

rfc1-rfc2-6
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-12042 imex-primary
xref: UnificationXref mint MINT-2197429
xref: RelationshipXref intact EBI-7517532 identity
evidence: Evidence 76165442-8b51-41d2-9f8d-c222580f987d IM-15332-12042 430873 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.787
comment: author-confidence:z-score: 5.80640983810369
data source: intact
participant: Protein uniprotkb P40348 identity 1529029541841
participant: Protein uniprotkb P38630 identity 1529029541840

ExperimentalForm 09b53560-7185-4841-9fab-586c59765d47
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 7e28c014-2107-4355-a430-66c48cb60111
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref mint P15790
type: RelationshipXref
id: P15790
db: mint

RelationshipXref intact EBI-7526761 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7526761
db: intact

med17_yeast
type: Protein
evidence: Evidence 750e7274-12a7-4ee4-8c8a-27e49c3a5993 p 431034
entity reference: med17_yeast
name: Mediator of RNA polymerase II transcription subunit 17
comment: psi-mi participant
data source: intact

ExperimentalForm 7d19e989-4a48-4ce5-9d99-bee733e72d08
type: ExperimentalForm
experimental feature: ModificationFeature 44505f7a-9125-4a9d-951d-8a7a43141d02 430968
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

lsp1_yeast
type: Protein
evidence: Evidence 1b927836-e7b9-4f15-8c92-80ddce7156bd p 431070
entity reference: Q12230
name: Sphingolipid long chain base-responsive protein LSP1
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7533756 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7533756
db: intact

ExperimentalForm 7520d48b-426e-4c0a-a646-0986f89775de
type: ExperimentalForm
experimental feature: ModificationFeature 22b3b916-cf93-4f72-9a60-7382162aefcb 433572
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 2e6ad96a-f2b9-44f1-b2b2-1f48a7d741ee
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpb8-yp225-1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-399 imex-primary
xref: RelationshipXref intact EBI-7528265 identity
xref: UnificationXref mint MINT-2204021
evidence: Evidence fad1c2c3-0aa9-4319-a6d1-a7b8d72d8e2e IM-15332-399 432337 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.989
comment: comment:mint
comment: author-confidence:z-score: 9.33156063801312
data source: intact
participant: rpab3_yeast
participant: yp225_yeast

rpb9-spt5-3
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-4782 imex-primary
xref: RelationshipXref intact EBI-7531470 identity
xref: UnificationXref mint MINT-2205132
evidence: Evidence 58a1222e-03cb-4b31-8311-3757fbf51270 IM-15332-4782 432573 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 1.6190645198992
comment: comment:mint
comment: author-confidence:reliability score: 0.866
data source: intact
participant: rpb9_yeast
participant: spt5_yeast

Evidence 4e6a4551-a62e-477e-b124-4b29238a05f9 IM-15332-9193 430613 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

Evidence 779ffa8e-f54c-4cb3-94ed-421671e23187 IM-15332-12869 430809 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref intact EBI-7516520 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7516520
db: intact

ExperimentalForm 267d5135-9f25-4b73-8f16-a32dff3ba461
type: ExperimentalForm
experimental feature: ModificationFeature 088fba35-cb9d-4187-9a39-584880abb307 431968
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-4876 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-4876
db: intact

RelationshipXref imex IM-15332-11651 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-11651
db: imex

RelationshipXref intact EBI-7516635 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7516635
db: intact

RelationshipXref intact EBI-7532998 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7532998
db: intact

med17_yeast
type: Protein
evidence: Evidence 0b0216ea-11dc-4ac1-b5d5-e65e3d9ba506 p 431022
entity reference: med17_yeast
name: Mediator of RNA polymerase II transcription subunit 17
comment: psi-mi participant
data source: intact

ExperimentalForm 50fd401f-fab1-49d5-89c7-db1245ef9723
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7516070 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7516070
db: intact

rpn1_yeast
type: ProteinReference
sequence: MVDESDKKQQTIDEQSQISPEKQTPNKKDKKKEEEEQLSEEDAKLKTDLELLVERLKEDDSSLYEASLNALKESIKNSTSSMTAVPKPLKFLRPTYPDLCSIYDKWTDPNLKSSLADVLSILAMTYSENGKHDSLRYRLLSDVSDFEGWGHEYIRHLALEIGEVYNDQVEKDAEDETSSDGSKSDGSAATSGFEFSKEDTLRLCLDIVPYFLKHNGEEDAVDLLLEIESIDKLPQFVDENTFQRVCQYMVACVPLLPPPEDVAFLKTAYSIYLSQNELTDAIALAVRLGEEDMIRSVFDATSDPVMHKQLAYILAAQKTSFEYEGVQDIIGNGKLSEHFLYLAKELNLTGPKVPEDIYKSHLDNSKSVFSSAGLDSAQQNLASSFVNGFLNLGYCNDKLIVDNDNWVYKTKGDGMTSAVASIGSIYQWNLDGLQQLDKYLYVDEPEVKAGALLGIGISASGVHDGEVEPALLLLQDYVTNPDTKISSAAILGLGIAFAGSKNDEVLGLLLPIAASTDLPIETAAMASLALAHVFVGTCNGDITTSIMDNFLERTAIELKTDWVRFLALALGILYMGQGEQVDDVLETISAIEHPMTSAIEVLVGSCAYTGTGDVLLIQDLLHRLTPKNVKGEEDADEEETAEGQTNSISDFLGEQVNEPTKNEEAEIEVDEMEVDAEGEEVEVKAEITEKKNGESLEGEEIKSEEKKGKSSDKDATTDGKNDDEEEEKEAGIVDELAYAVLGIALIALGEDIGKEMSLRHFGHLMHYGNEHIRRMVPLAMGIVSVSDPQMKVFDTLTRFSHDADLEVSMNSIFAMGLCGAGTNNARLAQLLRQLASYYSREQDALFITRLAQGLLHLGKGTMTMDVFNDAHVLNKVTLASILTTAVGLVSPSFMLKHHQLFYMLNAGIRPKFILALNDEGEPIKVNVRVGQAVETVGQAGRPKKITGWITQSTPVLLNHGERAELETDEYISYTSHIEGVVILKKNPDYREEE
xref: RelationshipXref rcsb pdb 5MPE
xref: RelationshipXref rcsb pdb 5MPD
xref: RelationshipXref rcsb pdb 5MPC
xref: RelationshipXref rcsb pdb 5MPB
xref: RelationshipXref reactome R-SCE-349425
xref: RelationshipXref reactome R-SCE-68949
xref: RelationshipXref rcsb pdb 3JCP
xref: RelationshipXref rcsb pdb 3JCO
xref: RelationshipXref interpro IPR002015
xref: RelationshipXref interpro IPR016024
xref: RelationshipXref reactome R-SCE-69601
xref: RelationshipXref refseq NP 011892 1
xref: RelationshipXref reactome R-SCE-69017
xref: RelationshipXref rcsb pdb 5WVK
xref: RelationshipXref rcsb pdb 5WVI
xref: RelationshipXref rcsb pdb 2N3W
xref: RelationshipXref rcsb pdb 2N3V
xref: RelationshipXref rcsb pdb 2N3U
xref: RelationshipXref rcsb pdb 2N3T
xref: RelationshipXref reactome R-SCE-8854050
xref: RelationshipXref reactome R-SCE-69229
xref: RelationshipXref go GO 0034515
xref: RelationshipXref go GO 0005634
xref: RelationshipXref go GO 0043161
xref: RelationshipXref interpro IPR011989
xref: RelationshipXref reactome R-SCE-1236978
xref: RelationshipXref go GO 0030674
xref: RelationshipXref go GO 0042176
xref: RelationshipXref reactome R-SCE-5689880
xref: RelationshipXref reactome R-SCE-174113
xref: RelationshipXref go GO 0030234
xref: RelationshipXref interpro IPR016643
xref: RelationshipXref reactome R-SCE-382556
xref: RelationshipXref uniprotkb D3DKX4 secondary-ac
xref: RelationshipXref go GO 0006511
xref: RelationshipXref mint P38764
xref: UnificationXref uniprot knowledgebase P38764
xref: RelationshipXref sgd S000001069
xref: RelationshipXref go GO 0008540
xref: RelationshipXref reactome R-SCE-5668541
xref: RelationshipXref rcsb pdb 4CR4
xref: RelationshipXref rcsb pdb 4CR3
xref: RelationshipXref rcsb pdb 4CR2
xref: RelationshipXref reactome R-SCE-450408
xref: RelationshipXref rcsb pdb 5A5B
xref: RelationshipXref reactome R-SCE-6798695
xref: RelationshipXref reactome R-SCE-983168
xref: RelationshipXref intact EBI-15913 identity
xref: RelationshipXref dip DIP-2876N
xref: RelationshipXref rcsb pdb 2NBW
xref: RelationshipXref reactome R-SCE-5687128
organism: http://identifiers.org/taxonomy/559292
name: Proteasome non-ATPase subunit 1
name: HRD2
name: YHR027C
name: HMG-CoA reductase degradation protein 2
name: RPD1
name: RPN1
name: NAS1
name: 26S proteasome regulatory subunit RPN1

RelationshipXref refseq NP 012189 2
type: RelationshipXref
id: NP_012189.2
db: refseq

uniprot-removed-ac
type: RelationshipTypeVocabulary

UnificationXref mint MINT-2206898
type: UnificationXref
id: MINT-2206898
db: mint

RelationshipXref intact EBI-7537033 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7537033
db: intact

rpa43_yeast
type: Protein
evidence: Evidence 5890d9bf-96f0-4860-a8ad-d8e0978c77c2 p 433094
entity reference: P46669
name: DNA-directed RNA polymerase I subunit RPA43
comment: psi-mi participant
data source: intact

pfs2_yeast
type: Protein
evidence: Evidence 7fd0588b-0be9-4c30-af4b-c8bcf2329640 p 430440
entity reference: P42841
name: Polyadenylation factor subunit 2
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7518615 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7518615
db: intact

rpb8-yp225
type: MolecularInteraction
xref: RelationshipXref intact EBI-7528185 identity
xref: RelationshipXref imex IM-15332-10442 imex-primary
xref: UnificationXref mint MINT-2204003
evidence: Evidence 15d29543-111b-4bfa-bd10-82639ef3e784 IM-15332-10442 432333 430156
interaction type: physical association
comment: author-confidence:z-score: 9.75475768116801
comment: author-confidence:reliability score: 0.989
comment: comment:homomint
comment: comment:mint
data source: intact
participant: Protein uniprotkb P20436 identity 1529029542571
participant: Protein uniprotkb Q08971 identity 1529029542570

RelationshipXref intact EBI-7520977 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7520977
db: intact

rpc31-rpo26
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-2757 imex-primary
xref: UnificationXref mint MINT-2206537
xref: RelationshipXref intact EBI-7534181 identity
evidence: Evidence 6796b16e-3c91-426a-b680-41ed8ae2b71a IM-15332-2757 432885 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.63
comment: author-confidence:z-score: -0.0260878511152019
comment: comment:mint
data source: intact
participant: Protein uniprotkb P20435 identity 1529029542847
participant: rpc7_yeast

RelationshipXref interpro IPR030387
type: RelationshipXref
id: IPR030387
db: interpro

ExperimentalForm a2776f26-568c-4d04-aaed-a951c5cb2eae
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref rcsb pdb 3SHJ
type: RelationshipXref
id: 3SHJ
db: protein data bank

rfa2-mnl1
type: MolecularInteraction
xref: RelationshipXref intact EBI-7517154 identity
xref: RelationshipXref imex IM-15332-4763 imex-primary
xref: UnificationXref mint MINT-2197068
evidence: Evidence 52a43b22-4eb7-4b20-a0f9-a389629808cc IM-15332-4763 430793 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 0.559810083557881
comment: author-confidence:reliability score: 0.792
comment: comment:mint
data source: intact
participant: mnl1_yeast
participant: Protein uniprotkb P26754 identity 1529029541800

UnificationXref mint MINT-2206880
type: UnificationXref
id: MINT-2206880
db: mint

ExperimentalForm 5208258f-0cda-48f3-8e17-48cd4603fabc
type: ExperimentalForm
experimental feature: ModificationFeature 6cde2ffd-0ec3-4713-8438-849ab859a517 432303
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7525700 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7525700
db: intact

Evidence 9612604d-8869-492e-b72f-c812f558e753 IM-15332-12481 431313 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

med6_yeast
type: ProteinReference
sequence: MNVTPLDELQWKSPEWIQVFGLRTENVLDYFAESPFFDKTSNNQVIKMQRQFSQLNDPNAAVNMTQNIMTLPDGKNGNLEEEFAYVDPARRQILFKYPMYMQLEEELMKLDGTEYVLSSVREPDFWVIRKQRRTNNSGVGSAKGPEIIPLQDYYIIGANIYQSPTIFKIVQSRLMSTSYHLNSTLESLYDLIEFQPSQGVHYKVPTDTSTTATAATNGNNAGGGSNKSSVRPTGGANMATVPSTTNVNMTVNTMGTGGQTIDNGTGRTGNGNMGITTEMLDKLMVTSIRSTPNYI
xref: RelationshipXref rcsb pdb 3RJ1
xref: RelationshipXref go GO 0070847
xref: RelationshipXref sgd S000001100
xref: RelationshipXref rcsb pdb 4V1O
xref: RelationshipXref mint P38782
xref: RelationshipXref go GO 0001128
xref: RelationshipXref refseq NP 011925 1
xref: RelationshipXref dip DIP-2093N
xref: RelationshipXref go GO 0016592
xref: RelationshipXref rcsb pdb 3J1O
xref: RelationshipXref go GO 0051123
xref: RelationshipXref go GO 0045944
xref: RelationshipXref rcsb pdb 5SVA
xref: UnificationXref uniprot knowledgebase P38782
xref: RelationshipXref interpro IPR016612
xref: RelationshipXref interpro IPR007018
xref: RelationshipXref rcsb pdb 4GWQ
xref: RelationshipXref rcsb pdb 4GWP
xref: RelationshipXref interpro IPR038566
xref: RelationshipXref uniprotkb D3DL07 secondary-ac
xref: RelationshipXref intact EBI-10667 identity
organism: http://identifiers.org/taxonomy/559292
name: Mediator of RNA polymerase II transcription subunit 6
name: MTR32
name: YHR058C
name: MED6
name: Mediator complex subunit 6

rpb7_yeast
type: Protein
evidence: Evidence da380ecd-ff66-4014-8d8a-8198c9f271ba p 432298
entity reference: rpb7_yeast
name: DNA-directed RNA polymerase II subunit RPB7
comment: psi-mi participant
data source: intact

RelationshipXref sgd S000002218
type: RelationshipXref
id: S000002218
db: sgd

rpa2_yeast
type: ProteinReference
sequence: MSKVIKPPGQARTADFRTLERESRFINPPKDKSAFPLLQEAVQPHIGSFNALTEGPDGGLLNLGVKDIGEKVIFDGKPLNSEDEISNSGYLGNKLSVSVEQVSIAKPMSNDGVSSAVERKVYPSESRQRLTSYRGKLLLKLKWSVNNGEENLFEVRDCGGLPVMLQSNRCHLNKMSPYELVQHKEESDEIGGYFIVNGIEKLIRMLIVQRRNHPMAIIRPSFANRGASYSHYGIQIRSVRPDQTSQTNVLHYLNDGQVTFRFSWRKNEYLVPVVMILKALCHTSDREIFDGIIGNDVKDSFLTDRLELLLRGFKKRYPHLQNRTQVLQYLGDKFRVVFQASPDQSDLEVGQEVLDRIVLVHLGKDGSQDKFRMLLFMIRKLYSLVAGECSPDNPDATQHQEVLLGGFLYGMILKEKIDEYLQNIIAQVRMDINRGMAINFKDKRYMSRVLMRVNENIGSKMQYFLSTGNLVSQSGLDLQQVSGYTVVAEKINFYRFISHFRMVHRGSFFAQLKTTTVRKLLPESWGFLCPVHTPDGSPCGLLNHFAHKCRISTQQSDVSRIPSILYSLGVAPASHTFAAGPSLCCVQIDGKIIGWVSHEQGKIIADTLRYWKVEGKTPGLPIDLEIGYVPPSTRGQYPGLYLFGGHSRMLRPVRYLPLDKEDIVGPFEQVYMNIAVTPQEIQNNVHTHVEFTPTNILSILANLTPFSDFNQSPRNMYQCQMGKQTMGTPGVALCHRSDNKLYRLQTGQTPIVKANLYDDYGMDNFPNGFNAVVAVISYTGYDMDDAMIINKSADERGFGYGTMYKTEKVDLALNRNRGDPITQHFGFGNDEWPKEWLEKLDEDGLPYIGTYVEEGDPICAYFDDTLNKTKIKTYHSSEPAYIEEVNLIGDESNKFQELQTVSIKYRIRRTPQIGDKFSSRHGQKGVCSRKWPTIDMPFSETGIQPDIIINPHAFPSRMTIGMFVESLAGKAGALHGIAQDSTPWIFNEDDTPADYFGEQLAKAGYNYHGNEPMYSGATGEELRADIYVGVVYYQRLRHMVNDKFQVRSTGPVNSLTMQPVKGRKRHGGIRVGEMERDALIGHGTSFLLQDRLLNSSDYTQASVCRECGSILTTQQSVPRIGSISTVCCRRCSMRFEDAKKLLTKSEDGEKIFIDDSQIWEDGQGNKFVGGNETTTVAIPFVLKYLDSELSAMGIRLRYNVEPK
xref: RelationshipXref uniprotkb D6W421 secondary-ac
xref: RelationshipXref go GO 0005829
xref: RelationshipXref interpro IPR007121
xref: RelationshipXref rcsb pdb 5M5Y
xref: RelationshipXref rcsb pdb 5M5X
xref: RelationshipXref rcsb pdb 5M5W
xref: RelationshipXref rcsb pdb 5M64
xref: RelationshipXref sgd S000006214
xref: RelationshipXref rcsb pdb 4YM7
xref: RelationshipXref interpro IPR007645
xref: RelationshipXref interpro IPR007644
xref: RelationshipXref rcsb pdb 5N5Z
xref: RelationshipXref rcsb pdb 5N5Y
xref: RelationshipXref go GO 0032549
xref: RelationshipXref rcsb pdb 5LMX
xref: RelationshipXref intact EBI-15736 identity
xref: RelationshipXref rcsb pdb 5N60
xref: RelationshipXref go GO 0046872
xref: RelationshipXref rcsb pdb 5N61
xref: RelationshipXref interpro IPR009674
xref: RelationshipXref interpro IPR007642
xref: RelationshipXref rcsb pdb 5W5Y
xref: RelationshipXref interpro IPR015712
xref: RelationshipXref rcsb pdb 5W66
xref: RelationshipXref rcsb pdb 5W65
xref: RelationshipXref rcsb pdb 5W64
xref: RelationshipXref interpro IPR007641
xref: RelationshipXref interpro IPR014724
xref: RelationshipXref rcsb pdb 5G5L
xref: RelationshipXref go GO 0003677
xref: RelationshipXref rcsb pdb 5M3M
xref: RelationshipXref go GO 0001054
xref: RelationshipXref rcsb pdb 4C3J
xref: RelationshipXref rcsb pdb 4C3I
xref: RelationshipXref rcsb pdb 4C3H
xref: RelationshipXref rcsb pdb 5M3F
xref: RelationshipXref dip DIP-135N
xref: RelationshipXref go GO 0006360
xref: RelationshipXref mint P22138
xref: UnificationXref uniprot knowledgebase P22138
xref: RelationshipXref rcsb pdb 4C2M
xref: RelationshipXref rcsb pdb 5OA1
xref: RelationshipXref reactome R-SCE-73762
xref: RelationshipXref go GO 0005736
xref: RelationshipXref go GO 0042254
xref: RelationshipXref go GO 0042790
xref: RelationshipXref interpro IPR037034
xref: RelationshipXref interpro IPR037033
xref: RelationshipXref refseq NP 015335 1
xref: RelationshipXref interpro IPR007120
organism: http://identifiers.org/taxonomy/559292
name: YPR010C
name: RRN2
name: RPA2
name: DNA-directed RNA polymerase I subunit RPA135
name: SRP3
name: DNA-directed RNA polymerase I polypeptide 2
name: YP9531.03C
name: DNA-directed RNA polymerase I 135 kDa polypeptide
name: RPA135

UnificationXref mint MINT-2195663
type: UnificationXref
id: MINT-2195663
db: mint

ExperimentalForm 8d048827-cd57-46ef-b602-bb084490295d
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref mint Q05775
type: RelationshipXref
id: Q05775
db: mint

rpc19-rpc34
type: MolecularInteraction
xref: RelationshipXref intact EBI-7532640 identity
xref: UnificationXref mint MINT-2205853
xref: RelationshipXref imex IM-15332-4783 imex-primary
evidence: Evidence 8cbfce07-790f-4e16-8650-f404758605b1 IM-15332-4783 432733 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.77
comment: author-confidence:z-score: 0.714848330655147
comment: comment:mint
data source: intact
participant: rpc6_yeast
participant: Protein uniprotkb P28000 identity 1529029542770

Evidence 7a0e9a37-95ab-46b1-b0bc-5bd3b4ac1909 IM-15332-1959 432513 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm 06232f68-fbf0-4707-b4e9-b80acfb2ee6b
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 6cf52532-61f7-4e08-97de-5a1e60506530
type: ExperimentalForm
experimental feature: ModificationFeature 2dc98c86-3924-482d-befa-b9f361bc78e0 431052
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpc17-rpo31-1
type: MolecularInteraction
xref: UnificationXref mint MINT-2205367
xref: RelationshipXref imex IM-15332-11255 imex-primary
xref: RelationshipXref intact EBI-7531859 identity
evidence: Evidence 8ff32777-53e2-46f2-a81e-0c3c502f4d0d IM-15332-11255 432625 430156
interaction type: physical association
comment: author-confidence:z-score: 2.05233955414399
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: rpc9_yeast
participant: rpc1_yeast

UnificationXref mint MINT-2206862
type: UnificationXref
id: MINT-2206862
db: mint

rpa43_yeast
type: Protein
evidence: Evidence e3c3b7ff-9b6d-4a64-b184-882e092e9ba7 p 433034
entity reference: P46669
name: DNA-directed RNA polymerase I subunit RPA43
comment: psi-mi participant
data source: intact

RelationshipXref go GO 0030846
type: RelationshipXref
id: GO:0030846
db: gene ontology

ExperimentalForm f71f70dd-0a02-40f5-ad74-1017dca022fa
type: ExperimentalForm
experimental feature: ModificationFeature 3635c22f-c6bf-4a04-ae3e-a8d509ff293f 431372
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

UnificationXref uniprot knowledgebase P06786
type: UnificationXref
id: P06786
db: uniprot knowledgebase

UnificationXref uniprot knowledgebase P07273
type: UnificationXref
id: P07273
db: uniprot knowledgebase

rpd3-rco1-1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-12889 imex-primary
xref: RelationshipXref intact EBI-7537607 identity
xref: UnificationXref mint MINT-2208302
evidence: Evidence 703fb5ec-7068-4817-adc2-11989c2bf0eb IM-15332-12889 433277 430156
interaction type: physical association
comment: author-confidence:z-score: 2.95918653488385
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb Q04779 identity 1529029543043
participant: rpd3_yeast

Evidence 0651ea21-ba84-4e8b-b36e-f4d55a00fe88 IM-15332-8022 431693 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

Evidence b6bd7c7f-5f25-42d9-96d8-ad3d8e98ce04 IM-15332-6374 431697 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref imex IM-15332-7639 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-7639
db: imex

ExperimentalForm d074f8be-8b88-421f-b4c2-2b92033f886d
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

Evidence 15d29543-111b-4bfa-bd10-82639ef3e784 IM-15332-10442 432333 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rot2-gtb1-1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-3583 imex-primary
xref: RelationshipXref intact EBI-7521417 identity
xref: UnificationXref mint MINT-2200220
evidence: Evidence d74d9e2a-0b37-48ed-853e-9aeae3d7add5 IM-15332-3583 431493 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 6.35014710094646
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P38138 identity 1529029542150
participant: Protein uniprotkb Q04924 identity 1529029542151

RelationshipXref interpro IPR001005
type: RelationshipXref
id: IPR001005
db: interpro

UnificationXref uniprot knowledgebase P0CS91
type: UnificationXref
id: P0CS91
db: uniprot knowledgebase

RelationshipXref intact EBI-7518922 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7518922
db: intact

rpc19-rpo26
type: MolecularInteraction
xref: UnificationXref mint MINT-2205871
xref: RelationshipXref imex IM-15332-12884 imex-primary
xref: RelationshipXref intact EBI-7532656 identity
evidence: Evidence 97a38630-1f2d-4853-bfd0-9323f057ce87 IM-15332-12884 432737 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 1.48008418329282
comment: author-confidence:reliability score: 0.631
comment: comment:mint
data source: intact
participant: Protein uniprotkb P20435 identity 1529029542772
participant: Protein uniprotkb P28000 identity 1529029542773

RelationshipXref refseq NP 014327 1
type: RelationshipXref
id: NP_014327.1
db: refseq

Evidence 77e3ffc6-05b4-4f75-b4b6-f795a701cd77 IM-15332-8422 432773 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref uniprot knowledgebase Q12230
type: UnificationXref
id: Q12230
db: uniprot knowledgebase

rir1_yeast
type: Protein
evidence: Evidence 8306ec64-abee-4aa0-9e26-c1d9a7dcd2b8 p 431391
entity reference: P21524
name: Ribonucleoside-diphosphate reductase large chain 1
comment: psi-mi participant
data source: intact

RelationshipXref go GO 0034727
type: RelationshipXref
id: GO:0034727
db: gene ontology

RelationshipXref rcsb pdb 3SDK
type: RelationshipXref
id: 3SDK
db: protein data bank

RelationshipXref go GO 0034724
type: RelationshipXref
id: GO:0034724
db: gene ontology

UnificationXref uniprot knowledgebase P13712
type: UnificationXref
id: P13712
db: uniprot knowledgebase

UnificationXref uniprot knowledgebase P15108
type: UnificationXref
id: P15108
db: uniprot knowledgebase

UnificationXref uniprot knowledgebase P16664
type: UnificationXref
id: P16664
db: uniprot knowledgebase

ExperimentalForm f0757f6e-27c3-45e2-ab1f-cc5a6bc0fa14
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref imex IM-15332-10025 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-10025
db: imex

rco1_yeast
type: Protein
evidence: Evidence a14307cb-7cea-4b20-a1c0-081cf97bf35d p 430391
entity reference: Q04779
name: Transcriptional regulatory protein RCO1
comment: psi-mi participant
data source: intact

rco1_yeast
type: Protein
evidence: Evidence 0ddbf876-fc85-4c28-8ab9-e8b4081bb1e0 p 430387
entity reference: Q04779
name: Transcriptional regulatory protein RCO1
comment: psi-mi participant
data source: intact

copa_yeast
type: ProteinReference
sequence: MKMLTKFESKSTRAKGIAFHPSRPWVLVALFSSTIQLWDYRMGTLLHRFEDHEGPVRGLDFHPTQPIFVSAGDDYTIKVWSLDTNKCLYTLTGHLDYVRTVFFHRELPWIISASDDQTIRIWNWQNRKEIACLTGHNHFVMCAQFHPTDDLIVSASLDETIRIWDISGLRKRHSAPGTSSFEEQMSAQQNLLDGSLGDCVVKFILEGHTRGVNWASFHPTLPLIVSGSDDRQVKLWRMSATKAWEVDTCRGHTNNVDSVIFHPHQNLIISVGEDKTLRVWDLDKRTPVKQFKRENDRFWLIAAHPHINLFGAAHDSGIMVFKLDRERPCSFIHQNQLFFVNAEKQIQSFNFQKRVASLPYASLKGIGQPWDAFRSISYNPSQHSVLVNEANGKFALVILPKQPVGAVEPTSVTQDTGNFATFVGRNRFVVYNKNTESVEVRSLENKVTRNIKVEETVRTIVAAGPGSVLVIHPREVILYDVQQGKKVSQLAVKNVKYVSWSLDGQYVALMSKHTITLATKKLELINSMHETIRIKSAAWDETGVLIYSTLNHIRYSLLNGDRGIIKTLEKTLYITKVQGKLVYCLNREGEIEILTIDPTEYRFKKALVNKNFPEVLRLIKDSNLVGQNIISYLQKSGYPEIALQFVQDPHIRFDLALEYGNLDVALDEAKKLNDSSTWERLIQEALAQGNASLAEMIYQTQHSFDKLSFLYLVTGDVNKLSKMQNIAQTREDFGSMLLNTFYNNSTKERSSIFAEGGSLPLAYAVAKANGDEAAASAFLEQAEVDEQDVTLPDQMDASNFVQRPVISKPLEKWPLKEAELSYFEKAVLGQIDDLTIDDETPAVNTTQEQEEPLGEENFNDEDIGEDEGAWDLGDEDLDVGEELPEEVEQGEITSPAQEVETAIWIKNSKLPAVLVAAGAFDAAVQALSKQVGVVKLEPLKKYFTNIYEGCRTYIPSTPCELPAQLGYVRAYDDTVSEDQILPYVPGLDVVNEKMNEGYKNFKLNKPDIAIECFREAIYRITLLMVDDAEDEKLAHKILETAREYILGLSIELERRSLKEGNTVRMLELAAYFTKAKLSPIHRTNALQVAMSQHFKHKNFLQASYFAGEFLKIISSGPRAEQARKIKNKADSMASDAIPIDFDPYAKFDICAATYKPIYEDTPSVSDPLTGSKYVITEKDKIDRIAMISKIGAPASGLRIRV
xref: UnificationXref uniprot knowledgebase P53622
xref: RelationshipXref go GO 0006891
xref: RelationshipXref go GO 0006890
xref: RelationshipXref interpro IPR006692
xref: RelationshipXref interpro IPR015943
xref: RelationshipXref intact EBI-4860 identity
xref: RelationshipXref rcsb pdb 3MV3
xref: RelationshipXref go GO 0006888
xref: RelationshipXref go GO 0006886
xref: RelationshipXref refseq NP 010136 1
xref: RelationshipXref go GO 0043130
xref: RelationshipXref mint P53622
xref: RelationshipXref go GO 0005198
xref: RelationshipXref rcsb pdb 3MV2
xref: RelationshipXref dip DIP-2582N
xref: RelationshipXref interpro IPR036322
xref: RelationshipXref interpro IPR019775
xref: RelationshipXref reactome R-SCE-6811434
xref: RelationshipXref interpro IPR010714
xref: RelationshipXref interpro IPR017986
xref: RelationshipXref rcsb pdb 3MKQ
xref: RelationshipXref reactome R-SCE-6807878
xref: RelationshipXref uniprotkb D6VRK3 secondary-ac
xref: RelationshipXref sgd S000002304
xref: RelationshipXref interpro IPR020472
xref: RelationshipXref go GO 0030126
xref: RelationshipXref interpro IPR011044
xref: RelationshipXref uniprotkb Q07595 secondary-ac
xref: RelationshipXref interpro IPR016391
xref: RelationshipXref go GO 0000139
xref: RelationshipXref interpro IPR001680
organism: http://identifiers.org/taxonomy/559292
name: D1578
name: Alpha-coat protein
name: Retrieval from endoplasmic reticulum protein 1
name: Secretory protein 22
name: Coatomer subunit alpha
name: Suppressor of osmo-sensitivity 1
name: SEC33
name: COP1
name: SOO1
name: RET1
name: YDL145C

rco1_yeast
type: Protein
evidence: Evidence 63b00483-bc0c-49c8-a492-49d239f8d3f5 p 430382
entity reference: Q04779
name: Transcriptional regulatory protein RCO1
comment: psi-mi participant
data source: intact

rco1_yeast
type: Protein
evidence: Evidence aa4ba2ad-c153-47c7-a9b5-59758e7a58fb p 430379
entity reference: Q04779
name: Transcriptional regulatory protein RCO1
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2205493
type: UnificationXref
id: MINT-2205493
db: mint

rco1_yeast
type: Protein
evidence: Evidence ef1a3d1e-fbe9-4517-ba17-61e3f00cb28c p 430374
entity reference: Q04779
name: Transcriptional regulatory protein RCO1
comment: psi-mi participant
data source: intact

ExperimentalForm ab1d7f68-55b7-49dc-bf05-385202e4d169
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

Evidence bd2c2d1c-fd34-49bc-93c4-fcea3b178c1e IM-15332-393 431837 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpc19-ret1-5
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-3994 imex-primary
xref: UnificationXref mint MINT-2206339
xref: RelationshipXref intact EBI-7533756 identity
evidence: Evidence 577c308b-d5e6-4412-bee6-564b09e32714 IM-15332-3994 432841 430156
interaction type: physical association
comment: author-confidence:z-score: 0.702602875613386
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P22276 identity 1529029542825
participant: Protein uniprotkb P28000 identity 1529029542824

RelationshipXref rcsb pdb 5M64
type: RelationshipXref
id: 5M64
db: protein data bank

rco1_yeast
type: Protein
evidence: Evidence 24227667-be8d-42cd-9268-2deabac7095a p 430371
entity reference: Q04779
name: Transcriptional regulatory protein RCO1
comment: psi-mi participant
data source: intact

rco1_yeast
type: Protein
evidence: Evidence 5280514b-25bc-4eda-96e3-f83e6328dd2d p 430367
entity reference: Q04779
name: Transcriptional regulatory protein RCO1
comment: psi-mi participant
data source: intact

UnificationXref uniprot knowledgebase P20435
type: UnificationXref
id: P20435
db: uniprot knowledgebase

rco1_yeast
type: Protein
evidence: Evidence 4a317f32-ba3b-4eb6-a3a1-3d50371be566 p 430362
entity reference: Q04779
name: Transcriptional regulatory protein RCO1
comment: psi-mi participant
data source: intact

UnificationXref uniprot knowledgebase P22276
type: UnificationXref
id: P22276
db: uniprot knowledgebase

rco1_yeast
type: Protein
evidence: Evidence e511cc5f-a2db-4bdb-9332-fc5e761a60cb p 430358
entity reference: Q04779
name: Transcriptional regulatory protein RCO1
comment: psi-mi participant
data source: intact

rco1_yeast
type: Protein
evidence: Evidence a58b452e-688c-4486-8882-3b3127a37879 p 430355
entity reference: Q04779
name: Transcriptional regulatory protein RCO1
comment: psi-mi participant
data source: intact

Evidence 9efe9916-164a-4448-8971-4ee2820ce0a7 IM-15332-7205 432329 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref uniprot knowledgebase P25344
type: UnificationXref
id: P25344
db: uniprot knowledgebase

UnificationXref uniprot knowledgebase P26755
type: UnificationXref
id: P26755
db: uniprot knowledgebase

RelationshipXref intact EBI-7527560 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7527560
db: intact

UnificationXref uniprot knowledgebase P27692
type: UnificationXref
id: P27692
db: uniprot knowledgebase

Evidence 3a3e30bd-91df-4eac-8b6e-0f85a3007e3a IM-15332-9205 431849 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref uniprot knowledgebase P29311
type: UnificationXref
id: P29311
db: uniprot knowledgebase

gin4_yeast
type: ProteinReference
sequence: MAINGNSIPAIKDNTIGPWKLGETLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGIEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAALETEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSDDEISREAQDLIRKILTVDPERRIKTRDILKHPLLQKYPSIRDSKSIRGLPREDTYLTPLSESNSSIDATILQNLVILWHGRDPEGIKEKLREPGANAEKTLYALLYRFKCDTQKELIKQQQVKKRQSISSVSVSPSKKVSTTPQRRRNRESLISVTSSRKKPISFNKFTASSASSSNLTTPGSSKRLSKNFSSKKKLSTIVNQSSPTPASRNKRASVINVEKNQKRASIFSTTKKNKRSSRSIKRMSLIPSMKRESVTTKLMSTYAKLAEDDDWEYIEKETKRTSSNFATLIDEIFEYEKYEQIRKEKEELERKVREAKAREELERRRRKQEEKERARKLLEKEDLKRKQEELKKQIEIDISDLEQELSKHKEEKLDGNIRSISAPMENEEKNINHLEVDIDNILRRRNFSLQTRPVSRLDPGIMFSSPTEEVSPVEPKRTENERLTTEKKILETIRRSKFLGSSFNIDKELKLSKMEYPSIIAPQRLSEERVVSDSNDGYESLILPKDGNGVSQLKDSTATTAPVSDGRLRKISEIRVPQFTRKSRHFSESNKRLSVLSMYSTKESFTNLVDILKNGNLDVNNQQSQRIPTPRSADDSEFLFETVNEEAEYTGNSSNDERLYDVGDSTIKDKSALKLNFADRFNGSNEAKQTDNLHLPILPPLNGDNELRKQNSQEGDQAHPKIKSMIPESGSSSHTEKEEENEEKEEKKPEQHKQEEDQEKREKVVDDMEPPLNKSVQKIREKNAGSQAKDHSKDHLKEHKQDKNTAIGNGSFFRKFSKSSDKTMELYAKISAKQLFNGLEKLLRGWTQYGLKNIKSHPNNLTLTGKLSSDNIFSLRSTLFEVNIYPRGKMSVVQFKKVSGSFKAVKKLVNEVENVLNKEGVLQK
xref: RelationshipXref go GO 0046777
xref: RelationshipXref interpro IPR011009
xref: RelationshipXref go GO 0005524
xref: RelationshipXref go GO 0000921
xref: RelationshipXref go GO 0005935
xref: RelationshipXref uniprotkb D6VTC9 secondary-ac
xref: RelationshipXref interpro IPR008271
xref: RelationshipXref go GO 0044879
xref: RelationshipXref interpro IPR000719
xref: RelationshipXref interpro IPR017441
xref: RelationshipXref refseq NP 010795 3
xref: RelationshipXref go GO 0006468
xref: RelationshipXref go GO 0035556
xref: RelationshipXref interpro IPR031850
xref: RelationshipXref intact EBI-7595 identity
xref: RelationshipXref go GO 0004674
xref: RelationshipXref go GO 0004672
xref: RelationshipXref go GO 0007117
xref: RelationshipXref mint Q12263
xref: RelationshipXref go GO 0005634
xref: RelationshipXref dip DIP-2260N
xref: RelationshipXref go GO 0005737
xref: UnificationXref uniprot knowledgebase Q12263
xref: RelationshipXref sgd S000002915
organism: http://identifiers.org/taxonomy/559292
name: Growth inhibitory protein 4
name: D9719.13
name: Serine/threonine-protein kinase GIN4
name: YDR507C
name: GIN4

RelationshipXref intact EBI-7516440 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7516440
db: intact

RelationshipXref refseq NP 015006 3
type: RelationshipXref
id: NP_015006.3
db: refseq

rco1_yeast
type: Protein
evidence: Evidence 123bade5-4493-4544-b0b2-7f9e5f4b0d30 p 430351
entity reference: Q04779
name: Transcriptional regulatory protein RCO1
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7525669 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7525669
db: intact

Evidence b4158e9b-359f-4ba4-9842-3f2ccd1bd5c7 IM-15332-4790 433137 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref mint MINT-2205475
type: UnificationXref
id: MINT-2205475
db: mint

UnificationXref uniprot knowledgebase Q12263
type: UnificationXref
id: Q12263
db: uniprot knowledgebase

RelationshipXref go GO 0004004
type: RelationshipXref
id: GO:0004004
db: gene ontology

RelationshipXref go GO 0004003
type: RelationshipXref
id: GO:0004003
db: gene ontology

RelationshipXref dip DIP-1414N
type: RelationshipXref
id: DIP-1414N
db: database of interacting proteins

ExperimentalForm 7c293e7d-ae68-47e4-92b0-b82b664c3209
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 912bac12-89ac-49cb-8ac7-9a0b9f2b6d70
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref imex IM-15332-5178 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5178
db: imex

ExperimentalForm 330e6b26-0b72-4609-8cce-20c187f341af
type: ExperimentalForm
experimental feature: ModificationFeature afbb58bd-bec6-417f-9447-311d189123bb 430411
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpl1a-hos3
type: MolecularInteraction
xref: UnificationXref mint MINT-2209724
xref: RelationshipXref intact EBI-7540477 identity
xref: RelationshipXref imex IM-15332-412 imex-primary
evidence: Evidence 1bbfe058-eb2d-4115-9e22-9dd7d2daef61 IM-15332-412 433593 430156
interaction type: physical association
comment: author-confidence:z-score: 5.7970694421426
comment: comment:mint
comment: author-confidence:reliability score: 0.681
data source: intact
participant: Protein uniprotkb P53030 identity 1529029543201
participant: Protein uniprotkb Q02959 identity 1529029543200

RelationshipXref refseq NP 011261 1
type: RelationshipXref
id: NP_011261.1
db: refseq

UnificationXref uniprot knowledgebase P32259
type: UnificationXref
id: P32259
db: uniprot knowledgebase

UnificationXref uniprot knowledgebase P33297
type: UnificationXref
id: P33297
db: uniprot knowledgebase

ExperimentalForm 146f92e4-4824-4910-8672-aea8110d3496
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref imex IM-15332-390 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-390
db: imex

UnificationXref uniprot knowledgebase P38615
type: UnificationXref
id: P38615
db: uniprot knowledgebase

UnificationXref uniprot knowledgebase P38922
type: UnificationXref
id: P38922
db: uniprot knowledgebase

UnificationXref mint MINT-2206808
type: UnificationXref
id: MINT-2206808
db: mint

UnificationXref molecular interactions ontology MI 0358
type: UnificationXref
id: MI:0358
db: molecular interactions ontology

rpc19-rpo31-1
type: MolecularInteraction
xref: UnificationXref mint MINT-2205943
xref: RelationshipXref intact EBI-7532749 identity
xref: RelationshipXref imex IM-15332-5594 imex-primary
evidence: Evidence 90fbe6cc-cb30-4b16-99a5-d809a3bb28b4 IM-15332-5594 432753 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 0.960987661937356
comment: comment:mint
comment: author-confidence:reliability score: 0.631
data source: intact
participant: Protein uniprotkb P28000 identity 1529029542780
participant: Protein uniprotkb P04051 identity 1529029542781

rpb10-rpo26
type: MolecularInteraction
xref: UnificationXref mint MINT-2202903
xref: RelationshipXref intact EBI-7525608 identity
xref: RelationshipXref imex IM-15332-9207 imex-primary
evidence: Evidence 190f063c-3353-4a2a-b727-64ef3fa35cfb IM-15332-9207 432089 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.579
comment: author-confidence:z-score: 5.07643325791603
comment: comment:mint
data source: intact
participant: Protein uniprotkb P20435 identity 1529029542448
participant: rpab5_yeast

RelationshipXref intact EBI-7524657 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7524657
db: intact

UnificationXref mint MINT-2202723
type: UnificationXref
id: MINT-2202723
db: mint

rpb9-rpo21-4
type: MolecularInteraction
xref: UnificationXref mint MINT-2204600
xref: RelationshipXref intact EBI-7530668 identity
xref: RelationshipXref imex IM-15332-4398 imex-primary
evidence: Evidence a5a20af8-2f97-4f1d-b830-1bf2b862a950 IM-15332-4398 432461 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 1.50650465401635
comment: comment:mint
comment: author-confidence:reliability score: 0.944
data source: intact
participant: Protein uniprotkb P04050 identity 1529029542634
participant: Protein uniprotkb P27999 identity 1529029542635

RelationshipXref uniprotkb E9P8V3 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: E9P8V3
db: uniprot knowledgebase

RelationshipXref sgd S000002299
type: RelationshipXref
id: S000002299
db: sgd

RelationshipXref imex IM-15332-3580 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-3580
db: imex

RelationshipXref intact EBI-7538541 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7538541
db: intact

http://identifiers.org/pubmed/16554755
type: PublicationXref
id: 16554755
db: pubmed

ExperimentalForm 5d08fc26-5742-4bd4-9de8-736a20857e6c
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 5c4b0881-fe51-438d-9cad-0fce6acc1479
type: ExperimentalForm
experimental feature: ModificationFeature 6cd3dbec-5615-47d5-a58a-8833f05c127c 432871
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpc40-rpc19-2
type: MolecularInteraction
xref: RelationshipXref intact EBI-7535933 identity
xref: UnificationXref mint MINT-2207564
xref: RelationshipXref imex IM-15332-9620 imex-primary
evidence: Evidence c34bbaa4-4d7c-4afb-86d4-265ea49a7c59 IM-15332-9620 433113 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 1.76643416068694
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P07703 identity 1529029542960
participant: rpac2_yeast

UnificationXref uniprot knowledgebase P40339
type: UnificationXref
id: P40339
db: uniprot knowledgebase

rpab5_yeast
type: Protein
evidence: Evidence 0217f012-4d46-49d5-83f1-a93dda73e978 p 432011
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

RelationshipXref interpro IPR005100
type: RelationshipXref
id: IPR005100
db: interpro

dna2_yeast
type: Protein
evidence: Evidence 5f950739-5cd3-4920-a5e7-bbf078b57236 p 430814
entity reference: P38859
name: DNA replication ATP-dependent helicase/nuclease DNA2
comment: psi-mi participant
data source: intact

rpa135-rpc34-1
type: MolecularInteraction
xref: UnificationXref mint MINT-2200292
xref: RelationshipXref imex IM-15332-10024 imex-primary
xref: RelationshipXref intact EBI-7521556 identity
evidence: Evidence 3fd64bae-6ee5-4898-9584-ab2c758bbab8 IM-15332-10024 431509 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 0.386800004727247
comment: author-confidence:reliability score: 0.688
comment: comment:mint
data source: intact
participant: Protein uniprotkb P22138 identity 1529029542158
participant: rpc6_yeast

UnificationXref uniprot knowledgebase P46669
type: UnificationXref
id: P46669
db: uniprot knowledgebase

rl12_yeast
type: Protein
evidence: Evidence 7d601126-6ff7-4969-a264-6d6d3b3a4f50 p 433571
entity reference: P17079
name: 60S ribosomal protein L12
comment: psi-mi participant
data source: intact

Evidence d692b60b-1997-44f0-a4be-1518e385b068 IM-15332-10043 433813 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref uniprot knowledgebase P49723
type: UnificationXref
id: P49723
db: uniprot knowledgebase

ExperimentalForm 00f080fa-aa95-481b-b4eb-9f9de642985b
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref go GO 0048188
type: RelationshipXref
id: GO:0048188
db: gene ontology

RelationshipXref imex IM-15332-6366 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-6366
db: imex

ExperimentalForm 5b0e4266-38cb-42ef-b92f-c0e7b9b8e4eb
type: ExperimentalForm
experimental feature: ModificationFeature cca6793f-c0e9-4522-ad9a-eb71d544c4ab 430372
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpab5_yeast
type: Protein
evidence: Evidence 5bdd2756-40e7-4c71-ac6f-5f99477a80a7 p 432018
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-11629 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-11629
db: imex

rpab5_yeast
type: Protein
evidence: Evidence eaa96ba7-bf2d-42e2-b917-82c97f9a46ae p 432030
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2204093
type: UnificationXref
id: MINT-2204093
db: mint

RelationshipXref imex IM-15332-7205 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-7205
db: imex

ExperimentalForm 5a309b6a-3654-48ba-8d3d-313dd49f0cdf
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 7dd3e421-da4d-4870-8c08-3dff0798cbb2
type: ExperimentalForm
experimental feature: ModificationFeature 4a8ed475-ca38-4c30-a490-d5d2e795b8cf 431016
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

UnificationXref mint MINT-2205439
type: UnificationXref
id: MINT-2205439
db: mint

UnificationXref mint MINT-2202741
type: UnificationXref
id: MINT-2202741
db: mint

RelationshipXref sgd S000003659
type: RelationshipXref
id: S000003659
db: sgd

RelationshipXref interpro IPR025829
type: RelationshipXref
id: IPR025829
db: interpro

rpn1-rpn2-16
type: MolecularInteraction
xref: RelationshipXref intact EBI-7543052 identity
xref: UnificationXref mint MINT-2210894
xref: RelationshipXref imex IM-15332-9217 imex-primary
evidence: Evidence eb86f7fa-e4f9-43a4-9496-5c10b6c00214 IM-15332-9217 433853 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.99
comment: author-confidence:z-score: 8.22254244234785
data source: intact
participant: rpn2_yeast
participant: Protein uniprotkb P38764 identity 1529029543330

rpb11-rpo26
type: MolecularInteraction
xref: UnificationXref mint MINT-2203389
xref: RelationshipXref imex IM-15332-7637 imex-primary
xref: RelationshipXref intact EBI-7526761 identity
evidence: Evidence 765eef45-b1a7-433b-98d6-3c1668057f0e IM-15332-7637 432197 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.989
comment: author-confidence:z-score: 3.55054248486034
comment: comment:mint
data source: intact
participant: Protein uniprotkb P20435 identity 1529029542503
participant: Protein uniprotkb P38902 identity 1529029542502

UnificationXref uniprot knowledgebase P50106
type: UnificationXref
id: P50106
db: uniprot knowledgebase

UnificationXref uniprot knowledgebase P51401
type: UnificationXref
id: P51401
db: uniprot knowledgebase

rpab5_yeast
type: Protein
evidence: Evidence e2006313-dd8b-493c-bc30-349bfc5cc374 p 432042
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7533913 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7533913
db: intact

rpab5_yeast
type: Protein
evidence: Evidence 4cf6d340-4d25-4798-8ab3-f154e10c0db1 p 432047
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-15443 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-15443
db: intact

RelationshipXref uniprotkb D6VXM8 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VXM8
db: uniprot knowledgebase

rpb11-rpo21-3
type: MolecularInteraction
xref: UnificationXref mint MINT-2203497
xref: RelationshipXref imex IM-15332-12486 imex-primary
xref: RelationshipXref intact EBI-7526885 identity
evidence: Evidence 0cfb7f86-3e1f-4988-b393-caa5fdb8f2c4 IM-15332-12486 432221 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 2.5968040553132
comment: comment:mint
comment: author-confidence:reliability score: 0.968
data source: intact
participant: Protein uniprotkb P38902 identity 1529029542514
participant: Protein uniprotkb P04050 identity 1529029542515

RelationshipXref intact EBI-7515661 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7515661
db: intact

ExperimentalForm fa384670-b796-4ec0-8c15-3e9b9bd7478e
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 89800cad-25d8-4fd6-9555-c7eae5301afe
type: ExperimentalForm
experimental feature: ModificationFeature 880e8c13-e18f-4a15-a594-e7567086ed13 432915
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7538086 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7538086
db: intact

UnificationXref mint MINT-2205421
type: UnificationXref
id: MINT-2205421
db: mint

ExperimentalForm e442c91f-2b08-4fa1-9a48-28c8e80352f3
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref refseq NP 015321 1
type: RelationshipXref
id: NP_015321.1
db: refseq

ExperimentalForm 87748c25-6537-499b-b459-a511dc52c9d4
type: ExperimentalForm
experimental feature: ModificationFeature 0730ae72-c0c7-4808-8ae8-839c9d9f4ca6 431492
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref refseq NP 015366 1
type: RelationshipXref
id: NP_015366.1
db: refseq

rco1-eaf3-1
type: MolecularInteraction
xref: RelationshipXref intact EBI-7515023 identity
xref: UnificationXref mint MINT-2195159
xref: RelationshipXref imex IM-15332-796 imex-primary
evidence: Evidence 38e1eaa6-956a-4e9c-83ee-f63c6cee5799 IM-15332-796 430369 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.989
comment: author-confidence:z-score: 0.114419363949249
comment: comment:mint
data source: intact
participant: eaf3_yeast
participant: rco1_yeast

UnificationXref mint MINT-2204075
type: UnificationXref
id: MINT-2204075
db: mint

RelationshipXref refseq NP 015395 1
type: RelationshipXref
id: NP_015395.1
db: refseq

Evidence 1376a105-32c9-4893-8101-7a021db023bb IM-15332-411 433573 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref imex IM-15332-6376 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-6376
db: imex

RelationshipXref rcsb pdb 3RZO
type: RelationshipXref
id: 3RZO
db: protein data bank

ExperimentalForm e6225cd5-147a-458f-97eb-c1fa7cd4f8b8
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref imex IM-15332-11639 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-11639
db: imex

ExperimentalForm 6fd9b232-a850-4ab8-b0a0-f2e844215000
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref rcsb pdb 3RZD
type: RelationshipXref
id: 3RZD
db: protein data bank

rpab5_yeast
type: Protein
evidence: Evidence f5db4f0a-59a3-4cbd-a689-921f7a713c6c p 432087
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

RelationshipXref uniprotkb D6VWA8 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VWA8
db: uniprot knowledgebase

rpac2_yeast
type: Protein
evidence: Evidence 94034c48-c8f2-408b-985a-3bb6ec470c90 p 433116
entity reference: P28000
name: DNA-directed RNA polymerases I and III subunit RPAC2
comment: psi-mi participant
data source: intact

RelationshipXref uniprotkb D6VUN6 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VUN6
db: uniprot knowledgebase

Evidence 55a7b2ef-aa3a-4725-a631-a2d495b3768d IM-15332-404 433045 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm 5c839ebb-4f82-4be2-9566-be84207b61e1
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref imex IM-15332-8019 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-8019
db: imex

tex1_yeast
type: Protein
evidence: Evidence 260d1643-e183-4132-a728-c34440458c64 p 431180
entity reference: tex1_yeast
name: Protein TEX1
comment: psi-mi participant
data source: intact

RelationshipXref refseq NP 015405 1
type: RelationshipXref
id: NP_015405.1
db: refseq

RelationshipXref dip DIP-3897N
type: RelationshipXref
id: DIP-3897N
db: database of interacting proteins

UnificationXref mint MINT-2205403
type: UnificationXref
id: MINT-2205403
db: mint

RelationshipXref refseq NP 015435 1
type: RelationshipXref
id: NP_015435.1
db: refseq

rpab5_yeast
type: Protein
evidence: Evidence fe1057c9-7e1b-4e93-8f53-9e273b256289 p 432094
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

ExperimentalForm de7f9cb2-38a3-4053-a4e8-e7ef60944576
type: ExperimentalForm
experimental feature: ModificationFeature a41cbb18-b959-4a83-9af2-70b7f2254ced 432896
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 6e170691-9016-413c-8a08-7d33c2c8edf3
type: ExperimentalForm
experimental feature: ModificationFeature a82a6efe-f760-40bf-8e1c-6613c1a0087d 432584
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-12486 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12486
db: imex

UnificationXref mint MINT-2204057
type: UnificationXref
id: MINT-2204057
db: mint

RelationshipXref mint P43620
type: RelationshipXref
id: P43620
db: mint

ExperimentalForm a8af5259-0457-4034-882d-5a3519402615
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref go GO 2000786
type: RelationshipXref
id: GO:2000786
db: gene ontology

ExperimentalForm 60092e02-2c81-4ea5-8d1c-44a74395ef98
type: ExperimentalForm
experimental feature: ModificationFeature cc2a3682-4dbb-48bb-b765-d695d230eb73 431139
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

UnificationXref mint MINT-2208212
type: UnificationXref
id: MINT-2208212
db: mint

UnificationXref uniprot knowledgebase P22579
type: UnificationXref
id: P22579
db: uniprot knowledgebase

rim4_yeast
type: Protein
evidence: Evidence 75582fbf-454e-4587-a178-1c91feed8846 p 431114
entity reference: rim4_yeast
name: Meiotic activator RIM4
comment: psi-mi participant
data source: intact

rpab5_yeast
type: Protein
evidence: Evidence 84c0e727-99d6-499a-af7b-aac63f2d74d6 p 432119
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

rpab5_yeast
type: Protein
evidence: Evidence 4f71f337-2123-45e4-8bba-e22ce20f07a5 p 432122
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-5988 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5988
db: imex

RelationshipXref intact EBI-7523778 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7523778
db: intact

ExperimentalForm 2e4b837a-3542-4eab-8241-768933e0e753
type: ExperimentalForm
experimental feature: ModificationFeature 7854a312-6acc-4399-9896-6c58ff512eb4 431543
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

Evidence f1a1c11d-f6af-4a77-8f53-994954d6f17e IM-15332-805 430973 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref intact EBI-7538393 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7538393
db: intact

ExperimentalForm 0746cf12-8ab9-4b06-9a54-77b933bf3720
type: ExperimentalForm
experimental feature: ModificationFeature 8072caf2-1f74-41cc-99a3-5e54240bac94 433907
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

UnificationXref uniprot knowledgebase P38779
type: UnificationXref
id: P38779
db: uniprot knowledgebase

rim4_yeast
type: Protein
evidence: Evidence 6d526b04-8a6f-46a2-8456-2e15f0445286 p 431111
entity reference: rim4_yeast
name: Meiotic activator RIM4
comment: psi-mi participant
data source: intact

rpc19-rpc31
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-815 imex-primary
xref: UnificationXref mint MINT-2205799
xref: RelationshipXref intact EBI-7532563 identity
evidence: Evidence dced7940-8d12-4536-8c79-33998ee516d1 IM-15332-815 432721 430156
interaction type: physical association
comment: comment:mint
comment: author-confidence:z-score: 9.02328739352385
comment: author-confidence:reliability score: 0.95
data source: intact
participant: Protein uniprotkb P28000 identity 1529029542765
participant: Protein uniprotkb P17890 identity 1529029542764

rim4_yeast
type: Protein
evidence: Evidence 399ce409-c164-424c-ab57-f60bf5951a63 p 431107
entity reference: rim4_yeast
name: Meiotic activator RIM4
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2202795
type: UnificationXref
id: MINT-2202795
db: mint

UnificationXref uniprot knowledgebase P47076
type: UnificationXref
id: P47076
db: uniprot knowledgebase

RelationshipXref rcsb pdb 3S8C
type: RelationshipXref
id: 3S8C
db: protein data bank

RelationshipXref rcsb pdb 3S8B
type: RelationshipXref
id: 3S8B
db: protein data bank

UnificationXref mint MINT-2204039
type: UnificationXref
id: MINT-2204039
db: mint

RelationshipXref imex IM-15332-9207 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-9207
db: imex

RelationshipXref rcsb pdb 3S87
type: RelationshipXref
id: 3S87
db: protein data bank

RelationshipXref imex IM-15332-10846 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-10846
db: imex

UnificationXref uniprot knowledgebase P38764
type: UnificationXref
id: P38764
db: uniprot knowledgebase

RelationshipXref intact EBI-15802 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-15802
db: intact

ExperimentalForm 11f0d9ea-f9e6-44dd-ac52-a08dfddc9d78
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref imex IM-15332-12496 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12496
db: imex

Evidence 961470a0-4606-4e30-a3b3-487d8811880f IM-15332-7189 430769 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

Evidence ba22c148-a7fe-4ec7-8137-b00fa20efb3d IM-15332-6369 431173 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpn8_yeast
type: Protein
evidence: Evidence 842a995b-2596-4628-9d77-6aae153a3f96 p 433872
entity reference: Q08723
name: 26S proteasome regulatory subunit RPN8
comment: psi-mi participant
data source: intact

rpn5_yeast
type: Protein
evidence: Evidence 7b5f5e78-709d-4fe3-ab4d-a440bbfed21f p 433918
entity reference: Q12250
name: 26S proteasome regulatory subunit RPN5
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2204021
type: UnificationXref
id: MINT-2204021
db: mint

RelationshipXref go GO 0006796
type: RelationshipXref
id: GO:0006796
db: gene ontology

xrn1_yeast
type: Protein
evidence: Evidence 95a83b9f-94fe-48a2-a7b0-33b292c12964 p 433238
entity reference: P22147
name: 5'-3' exoribonuclease 1
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-1227 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1227
db: imex

RelationshipXref rcsb pdb 5D0V
type: RelationshipXref
id: 5D0V
db: protein data bank

rpn8_yeast
type: Protein
evidence: Evidence 87022a44-336f-473d-b671-7febbcb422fc p 433850
entity reference: Q08723
name: 26S proteasome regulatory subunit RPN8
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-7628 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-7628
db: imex

ExperimentalForm 371279ce-5c73-4a8c-893a-4179831adc6b
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm b893782d-9de1-47aa-9ac3-2c93e26eb375
type: ExperimentalForm
experimental feature: ModificationFeature 5cc70003-62eb-4c9f-a0bf-d7c37afaa8ba 430580
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 0f2c12ca-c93d-4f2f-b087-c42e137c9c9e
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 1e6ef990-9c34-4735-92df-ea58438eda51
type: ExperimentalForm
experimental feature: ModificationFeature b78fb581-2bd3-4665-9de9-c006feb8e496 432084
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-8819 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-8819
db: imex

RelationshipXref reactome R-SCE-2730905
type: RelationshipXref
id: R-SCE-2730905
db: reactome

UnificationXref mint MINT-2204003
type: UnificationXref
id: MINT-2204003
db: mint

Evidence f4bf964a-563b-45aa-8de1-39ffb7349ea6 IM-15332-6782 432453 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm 9e2cccca-b245-431c-acf2-784f4089edaa
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7517756 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7517756
db: intact

reg1_yeast
type: Protein
evidence: Evidence 5301e6de-3d14-4896-8886-6a38a83121b7 p 430470
entity reference: Q00816
name: Resistance to glucose repression protein 1
comment: psi-mi participant
data source: intact

RelationshipXref interpro IPR003734
type: RelationshipXref
id: IPR003734
db: interpro

ExperimentalForm c83916a6-88e2-47dd-874c-51831bd08f8b
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ssn3_yeast
type: ProteinReference
sequence: MYNGKDRAQNSYQPMYQRPMQVQGQQQAQSFVGKKNTIGSVHGKAPMLMANNDVFTIGPYRARKDRMRVSVLEKYEVIGYIAAGTYGKVYKAKRQINSGTNSANGSSLNGTNAKIPQFDSTQPKSSSSMDMQANTNALRRNLLKDEGVTPGRIRTTREDVSPHYNSQKQTLIKKPLTVFYAIKKFKTEKDGVEQLHYTGISQSACREMALCRELHNKHLTTLVEIFLERKCVHMVYEYAEHDLLQIIHFHSHPEKRMIPPRMVRSIMWQLLDGVSYLHQNWVLHRDLKPANIMVTIDGCVKIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAELIGLQPIFKGEEAKLDSKKTVPFQVNQLQRILEVLGTPDQKIWPYLEKYPEYDQITKFPKYRDNLATWYHSAGGRDKHALSLLYHLLNYDPIKRIDAFNALEHKYFTESDIPVSENVFEGLTYKYPARRIHTNDNDIMNLGSRTKNNTQASGITAGAAANALGGLGVNRRILAAAAAAAAAVSGNNASDEPSRKKNRR
xref: RelationshipXref sgd S000005963
xref: RelationshipXref interpro IPR011009
xref: RelationshipXref go GO 0004693
xref: RelationshipXref go GO 0005524
xref: RelationshipXref mint P39073
xref: RelationshipXref interpro IPR008271
xref: RelationshipXref go GO 0051321
xref: RelationshipXref go GO 0000435
xref: RelationshipXref go GO 0046872
xref: RelationshipXref go GO 0000122
xref: RelationshipXref uniprotkb D6W3X1 secondary-ac
xref: RelationshipXref go GO 0060258
xref: RelationshipXref go GO 0070816
xref: RelationshipXref refseq NP 015283 1
xref: RelationshipXref go GO 0031648
xref: RelationshipXref go GO 0006468
xref: RelationshipXref interpro IPR000719
xref: RelationshipXref go GO 0008353
xref: RelationshipXref dip DIP-2574N
xref: UnificationXref uniprot knowledgebase P39073
xref: RelationshipXref intact EBI-20082 identity
xref: RelationshipXref go GO 0006351
xref: RelationshipXref go GO 0070481
xref: RelationshipXref go GO 0016592
xref: RelationshipXref go GO 0007346
organism: http://identifiers.org/taxonomy/559292
name: SSN3
name: Suppressor of RNA polymerase B SRB10
name: Meiotic mRNA stability protein kinase SSN3
name: GIG2
name: YPL042C
name: SRB10
name: ARE1
name: CDK8
name: Cyclin-dependent kinase 8
name: UME5

t2fa_yeast
type: Protein
evidence: Evidence 4eda0ada-3d23-4649-8d2a-c3740078b3cd p 432154
entity reference: P41895
name: Transcription initiation factor IIF subunit alpha
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-1576 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1576
db: imex

rpn8_yeast
type: Protein
evidence: Evidence 1b43945b-9a8a-48c3-b1f6-c0df0ba47463 p 433804
entity reference: Q08723
name: 26S proteasome regulatory subunit RPN8
comment: psi-mi participant
data source: intact

vps3_yeast
type: Protein
evidence: Evidence 0ff7abf8-c165-4500-a947-d98bb3466657 p 433242
entity reference: P23643
name: Vacuolar protein sorting-associated protein 3
comment: psi-mi participant
data source: intact

ExperimentalForm 2a791cec-853d-4ad8-a302-de310ce2be4f
type: ExperimentalForm
experimental feature: ModificationFeature ad01cd22-09c6-471c-b636-fe1854e09f21 432068
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7538154 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7538154
db: intact

rpb8-rpb3-1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-1585 imex-primary
xref: RelationshipXref intact EBI-7529665 identity
xref: UnificationXref mint MINT-2204292
evidence: Evidence a6f181b2-a616-4413-84df-3a2fd994f455 IM-15332-1585 432397 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 5.98121800673722
comment: comment:mint
comment: author-confidence:reliability score: 0.895
data source: intact
participant: Protein uniprotkb P16370 identity 1529029542603
participant: rpab3_yeast

UnificationXref mint MINT-2208950
type: UnificationXref
id: MINT-2208950
db: mint

UnificationXref uniprot knowledgebase P51862
type: UnificationXref
id: P51862
db: uniprot knowledgebase

RelationshipXref imex IM-15332-5177 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5177
db: imex

ExperimentalForm 212bbd25-9f99-434c-acab-07890bea49a6
type: ExperimentalForm
experimental feature: ModificationFeature 7d5130a3-b2c4-4f90-93e3-ec6aedebc4d7 432532
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 4463e403-62c9-4282-97f5-4f94c2c9c3e9
type: ExperimentalForm
experimental feature: ModificationFeature 3e512e57-8065-4565-adf5-7582044ae86f 433480
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref uniprotkb D6VUE2 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VUE2
db: uniprot knowledgebase

tho2-hrb1-2
type: MolecularInteraction
xref: RelationshipXref intact EBI-7519745 identity
xref: RelationshipXref imex IM-15332-389 imex-primary
xref: UnificationXref mint MINT-2199086
evidence: Evidence d8de61d3-7612-4e28-9361-70987480369b IM-15332-389 431241 430156
interaction type: physical association
comment: comment:mint
comment: author-confidence:reliability score: 0.762
comment: author-confidence:z-score: 0.0786183153664561
data source: intact
participant: Protein uniprotkb P53552 identity 1529029542024
participant: Protein uniprotkb P38922 identity 1529029542025

RelationshipXref rcsb pdb 3S2H
type: RelationshipXref
id: 3S2H
db: protein data bank

RelationshipXref rcsb pdb 2NVZ
type: RelationshipXref
id: 2NVZ
db: protein data bank

RelationshipXref rcsb pdb 2NVY
type: RelationshipXref
id: 2NVY
db: protein data bank

RelationshipXref rcsb pdb 2NVX
type: RelationshipXref
id: 2NVX
db: protein data bank

RelationshipXref rcsb pdb 3S2D
type: RelationshipXref
id: 3S2D
db: protein data bank

RelationshipXref rcsb pdb 2NVT
type: RelationshipXref
id: 2NVT
db: protein data bank

rpn1-rpn2-14
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-819 imex-primary
xref: RelationshipXref intact EBI-7542563 identity
xref: UnificationXref mint MINT-2210624
evidence: Evidence b9cd3e10-1c08-4a04-bf14-c10c12b05887 IM-15332-819 433793 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 2.42545831239299
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: rpn2_yeast
participant: Protein uniprotkb P38764 identity 1529029543300

RelationshipXref intact EBI-21537 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-21537
db: intact

RelationshipXref rcsb pdb 2NVQ
type: RelationshipXref
id: 2NVQ
db: protein data bank

RelationshipXref imex IM-15332-413 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-413
db: imex

RelationshipXref intact EBI-7517354 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7517354
db: intact

RelationshipXref go GO 0006744
type: RelationshipXref
id: GO:0006744
db: gene ontology

RelationshipXref rcsb pdb 3S1R
type: RelationshipXref
id: 3S1R
db: protein data bank

RelationshipXref sgd S000000433
type: RelationshipXref
id: S000000433
db: sgd

RelationshipXref go GO 0006740
type: RelationshipXref
id: GO:0006740
db: gene ontology

RelationshipXref rcsb pdb 3S1N
type: RelationshipXref
id: 3S1N
db: protein data bank

RelationshipXref rcsb pdb 3S1M
type: RelationshipXref
id: 3S1M
db: protein data bank

RelationshipXref intact EBI-7522597 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7522597
db: intact

RelationshipXref mint P21538
type: RelationshipXref
id: P21538
db: mint

ExperimentalForm e718e949-62a8-49ca-aecf-e2a509a808b4
type: ExperimentalForm
experimental feature: ModificationFeature 3774ea05-c00b-41bd-b95a-790a25ed9643 433260
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 8ffb9743-f537-496d-ad19-0a34580485b8
type: ExperimentalForm
experimental feature: ModificationFeature bc2f4375-e9f4-476b-8dd6-3b371a2426b0 432440
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref rcsb pdb 3S17
type: RelationshipXref
id: 3S17
db: protein data bank

RelationshipXref rcsb pdb 3S16
type: RelationshipXref
id: 3S16
db: protein data bank

RelationshipXref rcsb pdb 3S15
type: RelationshipXref
id: 3S15
db: protein data bank

RelationshipXref rcsb pdb 3S14
type: RelationshipXref
id: 3S14
db: protein data bank

UnificationXref uniprot knowledgebase Q12510
type: UnificationXref
id: Q12510
db: uniprot knowledgebase

RelationshipXref intact EBI-7542264 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7542264
db: intact

ExperimentalForm 5497b714-255a-4d47-8286-2aee520d80b7
type: ExperimentalForm
experimental feature: ModificationFeature ddd18563-56ed-4eb9-bad0-1103bf0e8f49 430959
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-4407 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-4407
db: imex

RelationshipXref dip DIP-6687N
type: RelationshipXref
id: DIP-6687N
db: database of interacting proteins

UnificationXref molecular interactions ontology MI 0524
type: UnificationXref
id: MI:0524
db: molecular interactions ontology

RelationshipXref interpro IPR018557
type: RelationshipXref
id: IPR018557
db: interpro

RelationshipXref interpro IPR031693
type: RelationshipXref
id: IPR031693
db: interpro

RelationshipXref intact EBI-7539001 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7539001
db: intact

RelationshipXref refseq NP 014547 1
type: RelationshipXref
id: NP_014547.1
db: refseq

RelationshipXref intact EBI-7517517 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7517517
db: intact

RelationshipXref imex IM-15332-10450 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-10450
db: imex

rpc40-rpo31
type: MolecularInteraction
xref: RelationshipXref intact EBI-7534866 identity
xref: RelationshipXref imex IM-15332-12060 imex-primary
xref: UnificationXref mint MINT-2207042
evidence: Evidence ecc9ca93-86a0-492b-9fc4-0d0de23b84b2 IM-15332-12060 432997 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.953
comment: author-confidence:z-score: 2.66937542697501
comment: comment:mint
data source: intact
participant: Protein uniprotkb P07703 identity 1529029542903
participant: Protein uniprotkb P04051 identity 1529029542902

RelationshipXref imex IM-15332-4385 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-4385
db: imex

UnificationXref mint MINT-2197195
type: UnificationXref
id: MINT-2197195
db: mint

RelationshipXref imex IM-15332-11254 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-11254
db: imex

RelationshipXref refseq NP 012395 1
type: RelationshipXref
id: NP_012395.1
db: refseq

ExperimentalForm 6a3d5229-dee1-4879-b28b-16ab977936ee
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7529399 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7529399
db: intact

RelationshipXref go GO 0090512
type: RelationshipXref
id: GO:0090512
db: gene ontology

mtc1_yeast
type: Protein
evidence: Evidence 8f71d7fa-b237-433d-b0dc-394ae449422c p 433348
entity reference: mtc1_yeast
name: Maintenance of telomere capping protein 1
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-12058 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12058
db: imex

tho2-srp1-1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-8804 imex-primary
xref: RelationshipXref intact EBI-7519310 identity
xref: UnificationXref mint MINT-2198852
evidence: Evidence 950c9415-079a-4aef-b800-8572f75072c0 IM-15332-8804 431189 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.989
comment: author-confidence:z-score: 6.15025594716564
comment: comment:mint
data source: intact
participant: tho2_yeast
participant: Protein uniprotkb Q02821 identity 1529029541999

RelationshipXref interpro IPR031675
type: RelationshipXref
id: IPR031675
db: interpro

RelationshipXref rcsb pdb 1Q46
type: RelationshipXref
id: 1Q46
db: protein data bank

UnificationXref molecular interactions ontology MI 0356
type: UnificationXref
id: MI:0356
db: molecular interactions ontology

ExperimentalForm 25f7dc28-f300-4528-8ee4-3f7e68c0d0b3
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref go GO 0090502
type: RelationshipXref
id: GO:0090502
db: gene ontology

RelationshipXref intact EBI-7523444 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7523444
db: intact

mtc1_yeast
type: Protein
evidence: Evidence 70dbb2c8-efda-40e5-88f2-4a4f7c4c8fa2 p 433370
entity reference: mtc1_yeast
name: Maintenance of telomere capping protein 1
comment: psi-mi participant
data source: intact

rpd3-sin3-2
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-8429 imex-primary
xref: RelationshipXref intact EBI-7538086 identity
xref: UnificationXref mint MINT-2208446
evidence: Evidence 0c0ecfcc-a3b8-42c0-b4ab-b25fcd5c828c IM-15332-8429 433309 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 1.00713111709292
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P22579 identity 1529029543059
participant: rpd3_yeast

ExperimentalForm 9eb7f0ac-c1c7-4a54-bce5-940602e52794
type: ExperimentalForm
experimental feature: ModificationFeature 6a1ca4cd-efb2-46d1-b246-a1149496fa15 431188
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

Evidence eef4974b-7143-49af-9832-768de98d5dbc IM-15332-12886 432809 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpc17-ret1-1
type: MolecularInteraction
xref: UnificationXref mint MINT-2205313
xref: RelationshipXref imex IM-15332-3589 imex-primary
xref: RelationshipXref intact EBI-7531733 identity
evidence: Evidence 2b851f15-b58f-4c5f-aee7-aa1b1e527b81 IM-15332-3589 432613 430156
interaction type: physical association
comment: author-confidence:z-score: 4.41306224751211
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: rpc2_yeast
participant: Protein uniprotkb P47076 identity 1529029542711

RelationshipXref interpro IPR018522
type: RelationshipXref
id: IPR018522
db: interpro

RelationshipXref interpro IPR031660
type: RelationshipXref
id: IPR031660
db: interpro

RelationshipXref intact EBI-7533478 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7533478
db: intact

Evidence 436a17f9-617e-4407-a213-d16374c92633 IM-15332-6771 430633 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpc3_yeast
type: Protein
evidence: Evidence 3147dd4f-a7ca-40e0-99fa-b3720ba1107e p 432932
entity reference: rpc3_yeast
name: DNA-directed RNA polymerase III subunit RPC3
comment: psi-mi participant
data source: intact

ExperimentalForm f01e1305-ed17-4cc4-b65f-9575681b3f82
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

Evidence cdffeebd-dda3-4d22-91cb-a3cb23f753a3 IM-15332-5175 431957 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref rcsb pdb 1K83
type: RelationshipXref
id: 1K83
db: protein data bank

Evidence 9a87e7a5-d6fd-43e3-8c5d-e78ff0905525 IM-15332-3987 432389 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref interpro IPR031657
type: RelationshipXref
id: IPR031657
db: interpro

RelationshipXref interpro IPR010997
type: RelationshipXref
id: IPR010997
db: interpro

RelationshipXref uniprotkb D6VRJ8 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VRJ8
db: uniprot knowledgebase

rpn13_yeast
type: ProteinReference
sequence: MSMSSTVIKFRAGVCEYNEDSRLCTPIPVQGEIEIKPNEEEELGFWDFEWRPTEKPVGRELDPISLILIPGETMWVPIKSSKSGRIFALVFSSNERYFFWLQEKNSGNLPLNELSAKDKEIYNKMIGVLNNSSESDEEESNDEKQKAQDVDVSMQD
xref: RelationshipXref go GO 0034515
xref: RelationshipXref go GO 0008541
xref: RelationshipXref rcsb pdb 5MPC
xref: UnificationXref uniprot knowledgebase O13563
xref: RelationshipXref mint O13563
xref: RelationshipXref sgd S000004413
xref: RelationshipXref rcsb pdb 5WVI
xref: RelationshipXref interpro IPR038633
xref: RelationshipXref go GO 0006511
xref: RelationshipXref uniprotkb D6VZ57 secondary-ac
xref: RelationshipXref go GO 0043130
xref: RelationshipXref intact EBI-32948 identity
xref: RelationshipXref rcsb pdb 2Z4D
xref: RelationshipXref rcsb pdb 5A5B
xref: RelationshipXref rcsb pdb 3JCP
xref: RelationshipXref refseq NP 013525 3
xref: RelationshipXref rcsb pdb 4CR3
xref: RelationshipXref dip DIP-4637N
xref: RelationshipXref rcsb pdb 4CR4
xref: RelationshipXref dip DIP-4637N identity
xref: RelationshipXref rcsb pdb 4CR2
xref: RelationshipXref interpro IPR006773
xref: RelationshipXref go GO 0005634
xref: RelationshipXref rcsb pdb 5WVK
xref: RelationshipXref go GO 0061133
xref: RelationshipXref go GO 0070628
xref: RelationshipXref rcsb pdb 5MPE
xref: RelationshipXref rcsb pdb 5MPD
xref: RelationshipXref rcsb pdb 3JCO
xref: RelationshipXref rcsb pdb 5MPB
organism: http://identifiers.org/taxonomy/559292
name: RPN13
name: DAQ1
name: Proteasome non-ATPase subunit 13
name: YLR421C
name: 26S proteasome regulatory subunit RPN13

rpab5_yeast
type: Protein
evidence: Evidence 0e154a37-1b6d-466c-baf4-c6a58dbdcad6 p 431907
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-4766 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-4766
db: imex

RelationshipXref rcsb pdb 2NOQ
type: RelationshipXref
id: 2NOQ
db: protein data bank

RelationshipXref mint P00817
type: RelationshipXref
id: P00817
db: mint

rpg1-tif5-3
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-11263 imex-primary
xref: RelationshipXref intact EBI-7539754 identity
xref: UnificationXref mint MINT-2209346
evidence: Evidence 98603dce-6ad5-4623-93f1-429b1e866f3c IM-15332-11263 433509 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 5.32210909546808
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P38431 identity 1529029543158
participant: eif3a_yeast

rpc3_yeast
type: Protein
evidence: Evidence 682decff-792c-4d15-8116-5044dd4797e4 p 432958
entity reference: rpc3_yeast
name: DNA-directed RNA polymerase III subunit RPC3
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 1K5Y
type: RelationshipXref
id: 1K5Y
db: protein data bank

RelationshipXref rcsb pdb 3RJ1
type: RelationshipXref
id: 3RJ1
db: protein data bank

Evidence 2700d3f8-bfe0-4b67-a16d-16d02ee7b2a0 IM-15332-12057 432485 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref mint MINT-2206790
type: UnificationXref
id: MINT-2206790
db: mint

rpa43-rpa34
type: MolecularInteraction
xref: RelationshipXref intact EBI-7523907 identity
xref: UnificationXref mint MINT-2201858
xref: RelationshipXref imex IM-15332-6377 imex-primary
evidence: Evidence d6c6f38f-a018-484f-9efa-31c5b797ab91 IM-15332-6377 431857 430156
interaction type: physical association
comment: author-confidence:z-score: 9.01007055193972
comment: author-confidence:reliability score: 0.917
comment: comment:mint
data source: intact
participant: Protein uniprotkb P46669 identity 1529029542332
participant: Protein uniprotkb P47006 identity 1529029542333

ExperimentalForm 4d1f3dc4-4985-471b-aca3-e7aa6638a81a
type: ExperimentalForm
experimental feature: ModificationFeature 86e19ae6-629d-40f0-8889-4410d21db067 431395
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref interpro IPR010971
type: RelationshipXref
id: IPR010971
db: interpro

RelationshipXref intact EBI-7524556 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7524556
db: intact

ExperimentalForm 1da43029-e77b-4f7d-bbf8-05d75904f772
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7517422 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7517422
db: intact

thp2_yeast
type: ProteinReference
sequence: MTKEEGRTYFESLCEEEQSLQESQTHLLNILDILSVLADPRSSDDLLTESLKKLPDLHRELINSSIRLRYDKYQTREAQLLEDTKTGRDVAAGVQNPKSISEYYSTFEHLNRDTLRYINLLKRLSVDLAKQVEVSDPSVTVYEMDKWVPSEKLQGILEQYCAPDTDIRGVDAQIKNYLDQIKMARAKFGLENKYSLKERLSTLTKELNHWRKEWDDIEMLMFGDDAHSMKKMIQKIDSLKSEINAPSESYPVDKEGDIVLE
xref: RelationshipXref go GO 0034063
xref: RelationshipXref go GO 0006406
xref: RelationshipXref go GO 0003676
xref: RelationshipXref dip DIP-4246N
xref: RelationshipXref refseq NP 012037 1
xref: RelationshipXref mint O13539
xref: RelationshipXref go GO 0006355
xref: RelationshipXref intact EBI-30898 identity
xref: RelationshipXref go GO 0006368
xref: RelationshipXref go GO 0000446
xref: RelationshipXref go GO 0000445
xref: RelationshipXref go GO 0000723
xref: RelationshipXref interpro IPR018557
xref: RelationshipXref sgd S000001210
xref: UnificationXref uniprot knowledgebase O13539
xref: RelationshipXref uniprotkb D3DLB6 secondary-ac
xref: RelationshipXref go GO 0006310
organism: http://identifiers.org/taxonomy/559292
name: YHR167W
name: THO complex subunit THP2
name: THP2

Evidence 89a09171-5ffc-4c0e-bd09-c5f84f96c1e9 IM-15332-10453 433657 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm 6f836bc6-2bd3-41aa-96d6-a56dc3b0b2fd
type: ExperimentalForm
experimental feature: ModificationFeature c89255b3-258a-4422-a6e0-71274fa5689d 432268
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7522665 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7522665
db: intact

mnl1_yeast
type: ProteinReference
sequence: MVCCLWVLLALLLHLDHVACEDDAYSFTSKELKAYKQEVKELFYFGFDNYLEHGYPYDEVKPISCVPKKRNFEDPTDQGTNDILGNFTITLIDSLTTIAILEDRPQFLKAVRLVERTFPDGNFDIDSTIQVFEITIRVIGSLLSSHLYATDPTKAVYLGDDYDGSLLRLAQNMADRLLPAYLTSTGLPMPRRNIKRKWDVSEFPEFLETENNVAAMASPMFEFTILSYLTGDPKYEKVTRYAFDKTWSLRTGLDLLPMSFHPEKLTPYTPMTGIGASIDSLFEYALKGAILFDDSELMEVWNVAYEALKTNCKNDWFFANVMADTGHLFVPWIDSLSAFFSGLQVLAGDLDDAIANHLMFLKMWNTFGGIPERWNFSPPEFPPLSPLERSGAVALDNILPLEWYPLRPEFFESTYFLYRATKDPFYLNIGVHLLKDLKQRFKSNCGFAGFQNVITGELQDRMETFVLSETLKYLYLLFDEENELHNSASDVIFSTEAHPMWLPQEVRSNYKRNAKFNNSVYSSHLEICQKKDREQAGENTLSQRIVGFAKSIFHKGPPDEEATDPIIDYTIDTELPGTCSIKPHHVIGDEFWYSPMLSNFDRLFEIDSRFAATLIKPSHMHNYNAIELEPGFYNRWSNPQFSTCLIPPTTEIFELLFDLPGYHQLNPLMLENKTITFETFGGRSRLKIEKLQIYQIDYYGDLITASTFQDVSRKDIFSNACDAVASLYSPTYLYRVVAINGRILPRHGSVQIKKHSPVLTSNGTREEDEFKMDGIGINDHSQLMLECTPIINLFIV
xref: RelationshipXref interpro IPR012341
xref: RelationshipXref go GO 0036508
xref: RelationshipXref go GO 0097466
xref: RelationshipXref interpro IPR036026
xref: RelationshipXref go GO 0030246
xref: UnificationXref uniprot knowledgebase P38888
xref: RelationshipXref uniprotkb D3DLF3 secondary-ac
xref: RelationshipXref go GO 0005788
xref: RelationshipXref go GO 1904382
xref: RelationshipXref go GO 1904380
xref: RelationshipXref intact EBI-24256 identity
xref: RelationshipXref go GO 0006986
xref: RelationshipXref sgd S000001247
xref: RelationshipXref refseq NP 012074 3
xref: RelationshipXref mint P38888
xref: RelationshipXref go GO 0004571
xref: RelationshipXref go GO 0006491
xref: RelationshipXref go GO 0005509
xref: RelationshipXref interpro IPR001382
xref: RelationshipXref go GO 0044322
xref: RelationshipXref dip DIP-1890N
xref: RelationshipXref go GO 0006486
xref: RelationshipXref go GO 0000139
xref: RelationshipXref reactome R-SCE-901032
organism: http://identifiers.org/taxonomy/559292
name: MNL1
name: HTM1
name: YHR204W
name: ER degradation-enhancing alpha-mannosidase-like protein 1

ExperimentalForm a9906b60-27d1-45ee-9030-3aae0ad210b8
type: ExperimentalForm
experimental feature: ModificationFeature b2397fee-7c9f-4a2f-bc4a-dd53b0e9d06a 432475
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

Evidence 3316fc52-1dd0-4ba3-b287-a4d1b243d9e6 IM-15332-8026 432693 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref mint MINT-2206772
type: UnificationXref
id: MINT-2206772
db: mint

csk21_yeast
type: Protein
evidence: Evidence 9af2637f-deb9-4fe9-8827-ba3c129812e0 p 431102
entity reference: csk21_yeast
name: Casein kinase II subunit alpha
comment: psi-mi participant
data source: intact

ExperimentalForm 428f6132-0fc4-44fd-8ad5-9542682350e3
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpac1_yeast
type: Protein
evidence: Evidence 5ce2240c-fabb-4c20-84e2-bccc6bba2058 p 432778
entity reference: P07703
name: DNA-directed RNA polymerases I and III subunit RPAC1
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-15475 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-15475
db: intact

ExperimentalForm 207d323c-a388-487d-99dc-2123bc6e9bf6
type: ExperimentalForm
experimental feature: ModificationFeature fe553f9e-e0ec-4821-bce3-715f721040b4 430740
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rfa1-rfa2-7
type: MolecularInteraction
xref: RelationshipXref intact EBI-7516885 identity
xref: RelationshipXref imex IM-15332-1948 imex-primary
xref: UnificationXref mint MINT-2196834
evidence: Evidence d220553b-4cb6-4a4a-a0a7-fa4a9bcd06a7 IM-15332-1948 430741 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 8.70607181962091
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P26754 identity 1529029541774
participant: rfa1_yeast

RelationshipXref refseq NP 015433 1
type: RelationshipXref
id: NP_015433.1
db: refseq

RelationshipXref mint P15646
type: RelationshipXref
id: P15646
db: mint

rpb7_yeast
type: Protein
evidence: Evidence 71e5035e-a331-47ff-886e-498a32179449 p 432078
entity reference: rpb7_yeast
name: DNA-directed RNA polymerase II subunit RPB7
comment: psi-mi participant
data source: intact

Evidence 585b8be5-1279-428f-b4c0-dc63cb333391 IM-15332-9216 433505 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref uniprotkb D6W1H9 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6W1H9
db: uniprot knowledgebase

ExperimentalForm 10592a81-6bab-4bf3-a3fd-b292a3c2726a
type: ExperimentalForm
experimental feature: ModificationFeature ed033512-b42d-4f11-81bf-5897afbfc4b5 433199
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-8806 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-8806
db: imex

RelationshipXref uniprotkb D6VVK2 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VVK2
db: uniprot knowledgebase

ExperimentalForm ab5a9f52-a6cc-4eb1-857b-b220a319f19d
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 9870f22a-2a16-48db-8f0b-d69ffc5a5fa0
type: ExperimentalForm
experimental feature: ModificationFeature 30b80cef-bcb7-434e-81ee-dd6a23ee79a6 432792
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7536003 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7536003
db: intact

RelationshipXref intact EBI-7518316 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7518316
db: intact

RelationshipXref imex IM-15332-7640 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-7640
db: imex

Evidence fb3e8554-3171-4839-848a-5e6a14f676f9 IM-15332-10028 431973 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref imex IM-15332-12868 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12868
db: imex

UnificationXref mint MINT-2206754
type: UnificationXref
id: MINT-2206754
db: mint

UnificationXref mint MINT-2211200
type: UnificationXref
id: MINT-2211200
db: mint

rpg1-tif5-2
type: MolecularInteraction
xref: UnificationXref mint MINT-2209328
xref: RelationshipXref intact EBI-7539718 identity
xref: RelationshipXref imex IM-15332-9216 imex-primary
evidence: Evidence 585b8be5-1279-428f-b4c0-dc63cb333391 IM-15332-9216 433505 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.99
comment: author-confidence:z-score: 9.60688723649788
data source: intact
participant: Protein uniprotkb P38431 identity 1529029543156
participant: Protein uniprotkb P38249 identity 1529029543157

rfa2-mnl1-1
type: MolecularInteraction
xref: RelationshipXref intact EBI-7517215 identity
xref: UnificationXref mint MINT-2197141
xref: RelationshipXref imex IM-15332-12869 imex-primary
evidence: Evidence 779ffa8e-f54c-4cb3-94ed-421671e23187 IM-15332-12869 430809 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.792
comment: comment:mint
comment: author-confidence:z-score: 0.124798729194633
data source: intact
participant: mnl1_yeast
participant: rfa2_yeast

ExperimentalForm 579d037e-3c3b-4176-84f3-831a88f1c58e
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 07c19f21-875e-42f3-a9c7-91bc56a13c35
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 5d94003b-8d07-4e96-9eb5-9ea3f5270500
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7517676 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7517676
db: intact

RelationshipXref intact EBI-7534934 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7534934
db: intact

Evidence 4e4b69be-5623-4820-abbc-7a027b251c04 IM-15332-12868 430625 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

tho2_yeast
type: Protein
evidence: Evidence b6ed5ed4-f006-41f8-b997-d45ce231a0d7 p 431219
entity reference: P53552
name: THO complex subunit 2
comment: psi-mi participant
data source: intact

ExperimentalForm ab6036a5-8f22-4b67-8cc9-be56578a60ff
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

tho2_yeast
type: Protein
evidence: Evidence 4f5c331c-7d22-4899-a9a0-71f313ce4ef1 p 431231
entity reference: P53552
name: THO complex subunit 2
comment: psi-mi participant
data source: intact

RelationshipXref interpro IPR025788
type: RelationshipXref
id: IPR025788
db: interpro

UnificationXref mint MINT-2206736
type: UnificationXref
id: MINT-2206736
db: mint

RelationshipXref intact EBI-4884 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-4884
db: intact

ExperimentalForm a56eb6cb-7b7d-4f38-9f4b-3f566ab7ca41
type: ExperimentalForm
experimental feature: ModificationFeature e7a2b8c6-c938-455b-839d-9a57bd684a61 431799
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpn1-rpn11-5
type: MolecularInteraction
xref: RelationshipXref intact EBI-7542844 identity
xref: UnificationXref mint MINT-2210750
xref: RelationshipXref imex IM-15332-9625 imex-primary
evidence: Evidence 46de95ea-ce97-4162-860e-4d09918902b2 IM-15332-9625 433821 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 8.918950256065
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P38764 identity 1529029543314
participant: rpn11_yeast

RelationshipXref mint Q05635
type: RelationshipXref
id: Q05635
db: mint

RelationshipXref go GO 0000407
type: RelationshipXref
id: GO:0000407
db: gene ontology

RelationshipXref refseq NP 010860 1
type: RelationshipXref
id: NP_010860.1
db: refseq

rnr1-rnr3-1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-4769 imex-primary
xref: UnificationXref mint MINT-2199554
xref: RelationshipXref intact EBI-7520448 identity
evidence: Evidence 356054ae-aa48-42a3-b898-7472c369769e IM-15332-4769 431345 430156
interaction type: physical association
comment: author-confidence:z-score: 3.04491269880974
comment: author-confidence:reliability score: 0.906
comment: comment:homomint
comment: comment:mint
data source: intact
participant: rir3_yeast
participant: Protein uniprotkb P21524 identity 1529029542077

RelationshipXref imex IM-15332-7650 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-7650
db: imex

RelationshipXref intact EBI-7539068 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7539068
db: intact

RelationshipXref intact EBI-8944 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-8944
db: intact

ExperimentalForm 7f5d538a-524e-4ae2-bbdb-28b72da37191
type: ExperimentalForm
experimental feature: ModificationFeature c488a3ae-ce8f-4e12-bbf2-b6f8056811c9 432703
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-12878 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12878
db: imex

tho2_yeast
type: Protein
evidence: Evidence 4282c9ad-2308-4981-9681-a83f05eebcd5 p 431250
entity reference: P53552
name: THO complex subunit 2
comment: psi-mi participant
data source: intact

ExperimentalForm 2f6e973e-013f-4243-a70f-caaa9ec91dad
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref go GO 0034605
type: RelationshipXref
id: GO:0034605
db: gene ontology

RelationshipXref intact EBI-7515103 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7515103
db: intact

RelationshipXref intact EBI-7595 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7595
db: intact

ExperimentalForm 47b414ee-5ca1-4dc8-9bba-f7dae2e99c37
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

nap1_yeast
type: Protein
evidence: Evidence 9e7f45bd-cde6-41df-abd1-29da2233aaf5 p 431082
entity reference: nap1_yeast
name: Nucleosome assembly protein
comment: psi-mi participant
data source: intact

nap1_yeast
type: Protein
evidence: Evidence b9b0763a-af73-4148-ad37-564ee2efca0d p 433604
entity reference: nap1_yeast
name: Nucleosome assembly protein
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7523489 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7523489
db: intact

RelationshipXref mint P53851
type: RelationshipXref
id: P53851
db: mint

tho2_yeast
type: Protein
evidence: Evidence cd1d6419-bd4a-486b-a299-36da22e157d6 p 431255
entity reference: P53552
name: THO complex subunit 2
comment: psi-mi participant
data source: intact

ExperimentalForm a91a53f8-7367-479a-b45a-2a043ccb4bdf
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 9cce6a6c-f3d4-4610-8a07-25e36ae67955
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref uniprotkb D6VW37 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VW37
db: uniprot knowledgebase

ExperimentalForm e3d11cdd-e88f-4c88-83eb-b7ae11ca3382
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 084aaa7b-703e-44c7-90bd-135130e4165e
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref mint MINT-2211110
type: UnificationXref
id: MINT-2211110
db: mint

ExperimentalForm 57071dab-425e-41fd-ac43-508a6082b76b
type: ExperimentalForm
experimental feature: ModificationFeature 2dfa5ea4-6ac0-4e6e-9c6a-f5158c56d115 432108
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref reactome R-SCE-382556
type: RelationshipXref
id: R-SCE-382556
db: reactome

ExperimentalForm e94381a6-282c-41ba-8bb5-d37e49b5fe28
type: ExperimentalForm
experimental feature: ModificationFeature 7c5944b3-358c-4308-a5c5-d4fe05480e1e 430644
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpn6_yeast
type: ProteinReference
sequence: MSLPGSKLEEARRLVNEKQYNEAEQVYLSLLDKDSSQSSAAAGASVDDKRRNEQETSILELGQLYVTMGAKDKLREFIPHSTEYMMQFAKSKTVKVLKTLIEKFEQVPDSLDDQIFVCEKSIEFAKREKRVFLKHSLSIKLATLHYQKKQYKDSLALINDLLREFKKLDDKPSLVDVHLLESKVYHKLRNLAKSKASLTAARTAANSIYCPTQTVAELDLMSGILHCEDKDYKTAFSYFFESFESYHNLTTHNSYEKACQVLKYMLLSKIMLNLIDDVKNILNAKYTKETYQSRGIDAMKAVAEAYNNRSLLDFNTALKQYEKELMGDELTRSHFNALYDTLLESNLCKIIEPFECVEISHISKIIGLDTQQVEGKLSQMILDKIFYGVLDQGNGWLYVYETPNQDATYDSALELVGQLNKVVDQLFEKASVLY
xref: RelationshipXref go GO 0034515
xref: RelationshipXref mint Q12377
xref: RelationshipXref go GO 0043248
xref: RelationshipXref reactome R-SCE-69601
xref: UnificationXref uniprot knowledgebase Q12377
xref: RelationshipXref uniprotkb D6VRQ3 secondary-ac
xref: RelationshipXref reactome R-SCE-68949
xref: RelationshipXref go GO 0008541
xref: RelationshipXref reactome R-SCE-983168
xref: RelationshipXref sgd S000002255
xref: RelationshipXref reactome R-SCE-6798695
xref: RelationshipXref reactome R-SCE-5687128
xref: RelationshipXref rcsb pdb 3JCP
xref: RelationshipXref reactome R-SCE-1236978
xref: RelationshipXref interpro IPR036390
xref: RelationshipXref dip DIP-1581N
xref: RelationshipXref go GO 0006511
xref: RelationshipXref intact EBI-308 identity
xref: RelationshipXref interpro IPR000717
xref: RelationshipXref rcsb pdb 3J47
xref: RelationshipXref go GO 0005198
xref: RelationshipXref rcsb pdb 5A5B
xref: RelationshipXref rcsb pdb 3JCO
xref: RelationshipXref reactome R-SCE-450408
xref: RelationshipXref reactome R-SCE-174113
xref: RelationshipXref reactome R-SCE-5668541
xref: RelationshipXref reactome R-SCE-8854050
xref: RelationshipXref reactome R-SCE-349425
xref: RelationshipXref refseq NP 010186 1
xref: RelationshipXref rcsb pdb 4CR4
xref: RelationshipXref rcsb pdb 4CR3
xref: RelationshipXref rcsb pdb 4CR2
xref: RelationshipXref go GO 0046686
xref: RelationshipXref reactome R-SCE-5689880
xref: RelationshipXref interpro IPR011990
xref: RelationshipXref reactome R-SCE-69017
xref: RelationshipXref rcsb pdb 5WVK
xref: RelationshipXref rcsb pdb 5WVI
xref: RelationshipXref rcsb pdb 5MPE
xref: RelationshipXref rcsb pdb 5MPD
xref: RelationshipXref rcsb pdb 5MPC
xref: RelationshipXref rcsb pdb 5MPB
xref: RelationshipXref reactome R-SCE-69229
xref: RelationshipXref reactome R-SCE-382556
xref: RelationshipXref rcsb pdb 3JCK
organism: http://identifiers.org/taxonomy/559292
name: D2381
name: RPN6
name: NAS4
name: 26S proteasome regulatory subunit RPN6
name: YDL097C
name: Proteasome non-ATPase subunit 4

RelationshipXref uniprotkb D6VWL6 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VWL6
db: uniprot knowledgebase

UnificationXref mint MINT-2205367
type: UnificationXref
id: MINT-2205367
db: mint

UnificationXref mint MINT-2202813
type: UnificationXref
id: MINT-2202813
db: mint

ExperimentalForm dfc718fc-ee84-4437-a5af-870b948161ed
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref uniprot knowledgebase Q12377
type: UnificationXref
id: Q12377
db: uniprot knowledgebase

rpab3_yeast
type: Protein
evidence: Evidence 8a6205db-f3d2-41d6-be3c-cb8d59753de2 p 432398
entity reference: P20436
name: DNA-directed RNA polymerases I, II, and III subunit RPABC3
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7533144 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7533144
db: intact

RelationshipXref mint P43588
type: RelationshipXref
id: P43588
db: mint

rnr1-rnr3-11
type: MolecularInteraction
xref: UnificationXref mint MINT-2199788
xref: RelationshipXref intact EBI-7520795 identity
xref: RelationshipXref imex IM-15332-11637 imex-primary
evidence: Evidence 1b9dc4e4-0fa5-44fd-bf73-56a75e110111 IM-15332-11637 431397 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.906
comment: comment:homomint
comment: author-confidence:z-score: 1.14087435890716
comment: comment:mint
data source: intact
participant: Protein uniprotkb P21524 identity 1529029542102
participant: Protein uniprotkb P21672 identity 1529029542103

rir3_yeast
type: Protein
evidence: Evidence c62ce399-76de-4fa9-8715-8a0b72f67b48 p 431346
entity reference: rir3_yeast
name: Ribonucleoside-diphosphate reductase large chain 2
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2206700
type: UnificationXref
id: MINT-2206700
db: mint

ExperimentalForm a0781541-86b9-4512-b476-0d271c696b61
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 2de4de57-5d9f-47cd-891a-1c441541898d
type: ExperimentalForm
experimental feature: ModificationFeature 602570e0-c1b2-4310-a4f3-2a05b0bc67e6 431675
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

tho2_yeast
type: Protein
evidence: Evidence 0d4cdf97-f471-442a-9e47-a27267f4f0bb p 431302
entity reference: P53552
name: THO complex subunit 2
comment: psi-mi participant
data source: intact

rpc6_yeast
type: Protein
evidence: Evidence 2d879477-b278-46c6-a13d-8f0281705a11 p 430520
entity reference: P32910
name: DNA-directed RNA polymerase III subunit RPC6
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7527826 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7527826
db: intact

RelationshipXref imex IM-15332-1958 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1958
db: imex

RelationshipXref interpro IPR025742
type: RelationshipXref
id: IPR025742
db: interpro

RelationshipXref imex IM-15332-403 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-403
db: imex

RelationshipXref intact EBI-7517437 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7517437
db: intact

UnificationXref mint MINT-2205349
type: UnificationXref
id: MINT-2205349
db: mint

UnificationXref mint MINT-2202831
type: UnificationXref
id: MINT-2202831
db: mint

RelationshipXref rcsb pdb 4V8Z
type: RelationshipXref
id: 4V8Z
db: protein data bank

RelationshipXref rcsb pdb 4V8Y
type: RelationshipXref
id: 4V8Y
db: protein data bank

RelationshipXref imex IM-15332-12046 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12046
db: imex

RelationshipXref rcsb pdb 4V8T
type: RelationshipXref
id: 4V8T
db: protein data bank

RelationshipXref rcsb pdb 4V92
type: RelationshipXref
id: 4V92
db: protein data bank

RelationshipXref rcsb pdb 4V91
type: RelationshipXref
id: 4V91
db: protein data bank

rir3_yeast
type: Protein
evidence: Evidence d615c034-03a3-449b-a5df-6720d12c72ec p 431386
entity reference: rir3_yeast
name: Ribonucleoside-diphosphate reductase large chain 2
comment: psi-mi participant
data source: intact

ExperimentalForm db527273-a958-44f3-9b64-750e6aa5a9b9
type: ExperimentalForm
experimental feature: ModificationFeature 0597d9be-ebb4-4b89-aa29-51673c18560d 432508
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7515055 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7515055
db: intact

UnificationXref mint MINT-2205331
type: UnificationXref
id: MINT-2205331
db: mint

RelationshipXref rcsb pdb 4V88
type: RelationshipXref
id: 4V88
db: protein data bank

RelationshipXref imex IM-15332-11244 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-11244
db: imex

RelationshipXref rcsb pdb 4V7R
type: RelationshipXref
id: 4V7R
db: protein data bank

RelationshipXref rcsb pdb 2NBW
type: RelationshipXref
id: 2NBW
db: protein data bank

RelationshipXref imex IM-15332-5185 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5185
db: imex

RelationshipXref intact EBI-7522633 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7522633
db: intact

rpab5_yeast
type: Protein
evidence: Evidence a893ace3-54a7-45b8-8452-5e9e9eb2f30c p 432130
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7537813 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7537813
db: intact

rpab5_yeast
type: Protein
evidence: Evidence 2aa72d7a-ea8b-4f2c-ad64-5acff11dd0d3 p 432126
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

rpc4_yeast
type: Protein
evidence: Evidence 0721132e-70cd-47a3-b4e4-8c4afcdf5f7a p 433262
entity reference: P25441
name: DNA-directed RNA polymerase III subunit RPC4
comment: psi-mi participant
data source: intact

rpc4_yeast
type: Protein
evidence: Evidence 9a373863-60e6-449b-a542-3c0cd67c0c2d p 433258
entity reference: P25441
name: DNA-directed RNA polymerase III subunit RPC4
comment: psi-mi participant
data source: intact

rpab5_yeast
type: Protein
evidence: Evidence 99a2586d-4ac7-4a8a-af8c-6d2a72b14cc4 p 432114
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

gin4_yeast
type: Protein
evidence: Evidence 974630c9-e277-4b78-9632-300482256296 p 431078
entity reference: gin4_yeast
name: Serine/threonine-protein kinase GIN4
comment: psi-mi participant
data source: intact

ExperimentalForm 4e760704-14c2-402b-a1e8-790a644c488e
type: ExperimentalForm
experimental feature: ModificationFeature 0cd58644-a950-4699-bc77-2f41c141767d 433791
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

Evidence dc8bd274-2cb2-4da9-8a48-d7ff57b94650 IM-15332-11638 431673 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

Evidence 6cb6140d-37f5-41fc-9693-02db433c976c IM-15332-4000 433701 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref uniprotkb D6W191 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6W191
db: uniprot knowledgebase

RelationshipXref intact EBI-7542300 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7542300
db: intact

rpab5_yeast
type: Protein
evidence: Evidence 970193e4-0410-4d5f-9ca3-7aa16e8ae6ff p 432111
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7531371 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7531371
db: intact

RelationshipXref refseq NP 015374 1
type: RelationshipXref
id: NP_015374.1
db: refseq

rpab5_yeast
type: Protein
evidence: Evidence 96f56e39-6b6c-4332-b24e-6f8654a17d32 p 432102
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

rpab5_yeast
type: Protein
evidence: Evidence 30a2cf21-7086-4354-8c98-ee42ca06138a p 432098
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

rpa190-rpa135-7
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-3584 imex-primary
xref: UnificationXref mint MINT-2200976
xref: RelationshipXref intact EBI-7522649 identity
evidence: Evidence 020d7ba1-5369-48f7-a3ac-dce9cfc897f2 IM-15332-3584 431661 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.99
comment: author-confidence:z-score: 1.46755942030964
data source: intact
participant: Protein uniprotkb P22138 identity 1529029542234
participant: Protein uniprotkb P10964 identity 1529029542235

UnificationXref mint MINT-2205313
type: UnificationXref
id: MINT-2205313
db: mint

ExperimentalForm c28a4d0c-e2bf-4ef1-99e5-79d0ec79021f
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm b6627f7c-0fc9-418a-85f5-6919a0c0c77c
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 8e1f4a6c-bc75-40dc-ac25-0a4bcf50352f
type: ExperimentalForm
experimental feature: ModificationFeature 12e8fb51-0e28-44d8-b7b1-2e5494436810 432631
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref go GO 0032126
type: RelationshipXref
id: GO:0032126
db: gene ontology

rpab5_yeast
type: Protein
evidence: Evidence 2b6f19ff-b4c2-4c9f-b211-1c63109fc23e p 432091
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

RelationshipXref reactome R-SCE-196836
type: RelationshipXref
id: R-SCE-196836
db: reactome

rpab5_yeast
type: Protein
evidence: Evidence a8a78f45-5a61-4c6c-a304-b392477aa646 p 432083
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

rpab5_yeast
type: Protein
evidence: Evidence a76a4b2d-3eda-477a-b91f-4427019af6b5 p 432079
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

Evidence bd11293b-8245-4f9d-a1b3-c84b20b0ad64 IM-15332-2360 432617 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpab5_yeast
type: Protein
evidence: Evidence ab7c5dff-37a6-431f-a112-c1da3ef151d9 p 432074
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

RelationshipXref reactome R-SCE-6782210
type: RelationshipXref
id: R-SCE-6782210
db: reactome

ExperimentalForm 17e7bb38-eee7-4ce2-acf0-7218843df3a3
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref go GO 0061188
type: RelationshipXref
id: GO:0061188
db: gene ontology

RelationshipXref interpro IPR037033
type: RelationshipXref
id: IPR037033
db: interpro

RelationshipXref go GO 0061186
type: RelationshipXref
id: GO:0061186
db: gene ontology

ExperimentalForm 802a9aba-322d-48fe-ae37-85f69a2e4b7f
type: ExperimentalForm
experimental feature: ModificationFeature 3cbdcf3f-0db1-445d-b7b9-fc1b5508ed6d 431768
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-6373 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-6373
db: imex

Evidence c8df9008-adb6-4d22-8ef3-d3e99460628f IM-15332-4777 431909 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref imex IM-15332-11636 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-11636
db: imex

rpab5_yeast
type: Protein
evidence: Evidence 44b095e0-28f0-4520-906e-58ed2e29a5e8 p 432071
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

ExperimentalForm ad3f1319-50a0-4e47-84ab-698f47ad60cb
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpab5_yeast
type: Protein
evidence: Evidence 2a154185-6652-4a62-961f-eded615dba1c p 432067
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

rpab5_yeast
type: Protein
evidence: Evidence f4be0346-8f3a-4b7a-85f5-c9509b330a4a p 432063
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

rpab5_yeast
type: Protein
evidence: Evidence 5990ee79-f282-40d1-9862-589546d377ed p 432059
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

rpab5_yeast
type: Protein
evidence: Evidence a36ec796-c641-4c54-b15b-1370bd3aeee6 p 432055
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 4V4B
type: RelationshipXref
id: 4V4B
db: protein data bank

UnificationXref mint MINT-2202885
type: UnificationXref
id: MINT-2202885
db: mint

RelationshipXref imex IM-15332-8016 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-8016
db: imex

RelationshipXref sgd S000001756
type: RelationshipXref
id: S000001756
db: sgd

rpa49_yeast
type: Protein
evidence: Evidence 811fb39e-ac88-4b75-8328-3f1c524a1e9e p 431628
entity reference: Q01080
name: DNA-directed RNA polymerase I subunit RPA49
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-795 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-795
db: imex

rpab5_yeast
type: Protein
evidence: Evidence 5c0c7daf-9106-4878-8b13-4cf3e79c48cd p 432051
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

UnificationXref molecular interactions ontology MI 0361
type: UnificationXref
id: MI:0361
db: molecular interactions ontology

rpab5_yeast
type: Protein
evidence: Evidence 0d5dc6a6-a401-4c19-9ae7-a8b8a6dde434 p 432039
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

UnificationXref uniprot knowledgebase Q12495
type: UnificationXref
id: Q12495
db: uniprot knowledgebase

rpab5_yeast
type: Protein
evidence: Evidence 21049a4b-c8f0-4332-958d-12600f1154d4 p 432035
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

rpa135-rpc34-2
type: MolecularInteraction
xref: UnificationXref mint MINT-2200346
xref: RelationshipXref intact EBI-7521698 identity
xref: RelationshipXref imex IM-15332-4388 imex-primary
evidence: Evidence ef491340-d05d-4f56-a716-fffb70dc7cfc IM-15332-4388 431521 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.688
comment: author-confidence:z-score: 0.0213772881259929
data source: intact
participant: Protein uniprotkb P22138 identity 1529029542164
participant: rpc6_yeast

rpac2_yeast
type: Protein
evidence: Evidence 0c2ea298-10e0-478c-a67e-196bc2bd300b p 431792
entity reference: P28000
name: DNA-directed RNA polymerases I and III subunit RPAC2
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 1JD2
type: RelationshipXref
id: 1JD2
db: protein data bank

RelationshipXref dip DIP-5816N
type: RelationshipXref
id: DIP-5816N
db: database of interacting proteins

rpa190-rpa43-2
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-1582 imex-primary
xref: UnificationXref mint MINT-2201426
xref: RelationshipXref intact EBI-7523331 identity
evidence: Evidence 23b35b58-f665-4873-a61e-b42e836fd97b IM-15332-1582 431761 430156
interaction type: physical association
comment: author-confidence:z-score: 9.09646351037538
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: rpa43_yeast
participant: rpa1_yeast

rpab5_yeast
type: Protein
evidence: Evidence 5a6b03b1-600e-4a25-b1aa-10c7d1291f2a p 432027
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

rpab5_yeast
type: Protein
evidence: Evidence 18ae19bb-1494-43da-846f-ff86ff6423b5 p 432023
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

RelationshipXref sgd S000000399
type: RelationshipXref
id: S000000399
db: sgd

RelationshipXref imex IM-15332-10842 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-10842
db: imex

RelationshipXref sgd S000000397
type: RelationshipXref
id: S000000397
db: sgd

RelationshipXref intact EBI-7535685 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7535685
db: intact

RelationshipXref go GO 0061157
type: RelationshipXref
id: GO:0061157
db: gene ontology

RelationshipXref reactome R-SCE-77075
type: RelationshipXref
id: R-SCE-77075
db: reactome

RelationshipXref go GO 0000461
type: RelationshipXref
id: GO:0000461
db: gene ontology

RelationshipXref go GO 0000462
type: RelationshipXref
id: GO:0000462
db: gene ontology

RelationshipXref sgd S000001733
type: RelationshipXref
id: S000001733
db: sgd

RelationshipXref rcsb pdb 4V1O
type: RelationshipXref
id: 4V1O
db: protein data bank

RelationshipXref rcsb pdb 4V1N
type: RelationshipXref
id: 4V1N
db: protein data bank

RelationshipXref rcsb pdb 4V1M
type: RelationshipXref
id: 4V1M
db: protein data bank

ExperimentalForm cb37c6fd-40ee-4d2d-b178-61d32a7b6da7
type: ExperimentalForm
experimental feature: ModificationFeature 855e5232-92d8-469c-bb86-484c67145ae2 433779
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpab5_yeast
type: Protein
evidence: Evidence 6c6030a9-390a-4540-9c24-7cccf95f9013 p 432007
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

rpab5_yeast
type: Protein
evidence: Evidence d8f5efeb-c3a4-4422-aa50-920bb19920dd p 432002
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

rpab5_yeast
type: Protein
evidence: Evidence c5ce61c7-06c2-4ccd-be3f-67751eb5229e p 431998
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

rpab5_yeast
type: Protein
evidence: Evidence 2322cf98-eecd-4e0e-b00a-9c88645994bd p 431995
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

ExperimentalForm 79560b14-d332-4921-ac60-2113c21f18b3
type: ExperimentalForm
experimental feature: ModificationFeature 90456d45-7090-43b1-9969-595accbccfe2 432635
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-9204 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-9204
db: imex

ExperimentalForm 5678afcc-e989-4f6f-9fcb-eb60269014c0
type: ExperimentalForm
experimental feature: ModificationFeature 7a89dcaf-66eb-4c60-8065-894670f84ae7 432955
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref go GO 0000019
type: RelationshipXref
id: GO:0000019
db: gene ontology

RelationshipXref intact EBI-7537148 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7537148
db: intact

RelationshipXref rcsb pdb 2MZT
type: RelationshipXref
id: 2MZT
db: protein data bank

RelationshipXref rcsb pdb 2MZS
type: RelationshipXref
id: 2MZS
db: protein data bank

RelationshipXref rcsb pdb 2MZR
type: RelationshipXref
id: 2MZR
db: protein data bank

RelationshipXref rcsb pdb 2MZQ
type: RelationshipXref
id: 2MZQ
db: protein data bank

Evidence 128c684e-1318-4be7-9ffa-248686929a84 IM-15332-10045 433921 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm 472d87a2-dc5f-4c82-b416-fcb3b993ccff
type: ExperimentalForm
experimental feature: ModificationFeature 511ab769-fcd0-475d-9776-67663b293655 430548
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7522183 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7522183
db: intact

Evidence f65aecfa-ed7a-446d-bb43-b4930a7e2665 IM-15332-798 430585 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref imex IM-15332-2746 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-2746
db: imex

rpb3_yeast
type: Protein
evidence: Evidence 1911ab64-085b-4311-85b5-fb0102a1ca98 p 432194
entity reference: P16370
name: DNA-directed RNA polymerase II subunit RPB3
comment: psi-mi participant
data source: intact

RelationshipXref go GO 0061133
type: RelationshipXref
id: GO:0061133
db: gene ontology

RelationshipXref refseq NP 009644 3
type: RelationshipXref
id: NP_009644.3
db: refseq

rpd3_yeast
type: Protein
evidence: Evidence b05f2b6a-c04c-4f29-8b3c-bd5bc1e746ad p 433326
entity reference: rpd3_yeast
name: Histone deacetylase RPD3
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-15240 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-15240
db: intact

RelationshipXref intact EBI-7527985 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7527985
db: intact

UnificationXref molecular interactions ontology MI 0471
type: UnificationXref
id: MI:0471
db: molecular interactions ontology

ExperimentalForm 835830e2-d33d-4625-9d6b-6b54f2b9c45e
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpn5_yeast
type: Protein
evidence: Evidence cdc174ef-7867-4cb9-a249-650b17091660 p 433676
entity reference: Q12250
name: 26S proteasome regulatory subunit RPN5
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7517596 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7517596
db: intact

RelationshipXref rcsb pdb 4O8X
type: RelationshipXref
id: 4O8X
db: protein data bank

RelationshipXref intact EBI-7531486 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7531486
db: intact

RelationshipXref rcsb pdb 3QT1
type: RelationshipXref
id: 3QT1
db: protein data bank

RelationshipXref uniprotkb D6VZG4 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VZG4
db: uniprot knowledgebase

UnificationXref uniprot knowledgebase P38630
type: UnificationXref
id: P38630
db: uniprot knowledgebase

RelationshipXref dip DIP-7126N
type: RelationshipXref
id: DIP-7126N
db: database of interacting proteins

rpd3_yeast
type: Protein
evidence: Evidence d95949e5-8249-4e15-bf62-110077cc8fad p 433343
entity reference: rpd3_yeast
name: Histone deacetylase RPD3
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-7638 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-7638
db: imex

ExperimentalForm 7ee1867b-925a-4816-89ae-2bc3befcc686
type: ExperimentalForm
experimental feature: ModificationFeature b1fa3f57-f47b-42fa-b616-7e4de9305183 432287
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref interpro IPR018494
type: RelationshipXref
id: IPR018494
db: interpro

ExperimentalForm dc6fc701-afda-473f-8fb4-3e6cdd2be605
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm a8d8f6be-26c0-4823-bd6f-ed3bf96b992c
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref uniprotkb D6VY97 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VY97
db: uniprot knowledgebase

UnificationXref uniprot knowledgebase P38629
type: UnificationXref
id: P38629
db: uniprot knowledgebase

UnificationXref uniprot knowledgebase P38626
type: UnificationXref
id: P38626
db: uniprot knowledgebase

rpa190-rpb8
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-1213 imex-primary
xref: RelationshipXref intact EBI-7523077 identity
xref: UnificationXref mint MINT-2201210
evidence: Evidence 489600d4-b57b-4fa0-b591-d89babf56201 IM-15332-1213 431713 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 3.92709738024038
comment: author-confidence:reliability score: 0.947
comment: comment:mint
data source: intact
participant: Protein uniprotkb P20436 identity 1529029542260
participant: rpa1_yeast

Evidence 064c388d-c439-4256-9466-4b3f4347d7ff IM-15332-8806 431537 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rgr1-ssn8
type: MolecularInteraction
xref: RelationshipXref intact EBI-7518516 identity
xref: RelationshipXref imex IM-15332-10430 imex-primary
xref: UnificationXref mint MINT-2198168
evidence: Evidence 973401ef-2577-4e06-872e-8852699f55a8 IM-15332-10430 431037 430156
interaction type: physical association
comment: author-confidence:z-score: 3.61708760577451
comment: comment:mint
comment: author-confidence:reliability score: 0.681
data source: intact
participant: Protein uniprotkb P47821 identity 1529029541923
participant: Protein uniprotkb P19263 identity 1529029541922

ExperimentalForm 25ad2652-30e1-4a1e-a144-1936ad8eacc3
type: ExperimentalForm
experimental feature: ModificationFeature 0c31daaa-8d66-4fe3-81c3-53a3401377b0 432519
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7523077 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7523077
db: intact

Evidence 836636b9-6d18-4c93-a0ff-851bce326f4b IM-15332-1574 430889 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpd3_yeast
type: Protein
evidence: Evidence af96202c-accb-4dfc-ac08-16ab0d77bdbd p 433367
entity reference: rpd3_yeast
name: Histone deacetylase RPD3
comment: psi-mi participant
data source: intact

ExperimentalForm bc5de3a4-dc07-47d4-8d96-ba81b8b561a7
type: ExperimentalForm
experimental feature: ModificationFeature b460ca0c-0767-4f62-b2b8-13b7b0c63bdd 431864
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref go GO 2000617
type: RelationshipXref
id: GO:2000617
db: gene ontology

RelationshipXref go GO 2000616
type: RelationshipXref
id: GO:2000616
db: gene ontology

RelationshipXref go GO 0006656
type: RelationshipXref
id: GO:0006656
db: gene ontology

UnificationXref uniprot knowledgebase Q12432
type: UnificationXref
id: Q12432
db: uniprot knowledgebase

ExperimentalForm 58a2d6f1-0951-4d35-a537-86bd215c275d
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref sgd S000000340
type: RelationshipXref
id: S000000340
db: sgd

RelationshipXref interpro IPR003618
type: RelationshipXref
id: IPR003618
db: interpro

RelationshipXref interpro IPR003617
type: RelationshipXref
id: IPR003617
db: interpro

Evidence 59362075-356e-45ff-82ca-9265ff0e27aa IM-15332-384 430377 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpg1-prt1-11
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-7649 imex-primary
xref: RelationshipXref intact EBI-7539574 identity
xref: UnificationXref mint MINT-2209256
evidence: Evidence cbfc1303-77e7-47d7-996f-a71974d4099c IM-15332-7649 433489 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 5.47971172019561
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P38249 identity 1529029543149
participant: Protein uniprotkb P06103 identity 1529029543148

gbp2_yeast
type: ProteinReference
sequence: MERELGMYGNDRSRSRSPVRRRLSDDRDRYDDYNDSSSNNGNGSRRQRRDRGSRFNDRYDQSYGGSRYHDDRNWPPRRGGRGRGGSRSFRGGRGGGRGRTLGPIVERDLERQFDATKRNFENSIFVRNLTFDCTPEDLKELFGTVGEVVEADIITSKGHHRGMGTVEFTKNESVQDAISKFDGALFMDRKLMVRQDNPPPEAAKEFSKKATREEIDNGFEVFIINLPYSMNWQSLKDMFKECGHVLRADVELDFNGFSRGFGSVIYPTEDEMIRAIDTFNGMEVEGRVLEVREGRFNKRKNNDRYNQRREDLEDTRGTEPGLAQDAAVHIDETAAKFTEGVNPGGDRNCFIYCSNLPFSTARSDLFDLFGPIGKINNAELKPQENGQPTGVAVVEYENLVDADFCIQKLNNYNYGGCSLQISYARRD
xref: RelationshipXref mint P25555
xref: RelationshipXref interpro IPR012677
xref: RelationshipXref go GO 0071028
xref: RelationshipXref go GO 0005634
xref: RelationshipXref go GO 0043047
xref: RelationshipXref uniprotkb D6VR01 secondary-ac
xref: RelationshipXref interpro IPR035979
xref: RelationshipXref interpro IPR000504
xref: UnificationXref uniprot knowledgebase P25555
xref: RelationshipXref go GO 0010494
xref: RelationshipXref dip DIP-2735N identity
xref: RelationshipXref go GO 0000723
xref: RelationshipXref go GO 0000781
xref: RelationshipXref go GO 0005829
xref: RelationshipXref dip DIP-2735N
xref: RelationshipXref refseq NP 009916 1
xref: RelationshipXref rcsb pdb 2MZQ
xref: RelationshipXref intact EBI-7410 identity
xref: RelationshipXref go GO 0003729
xref: RelationshipXref sgd S000000517
xref: RelationshipXref go GO 0016973
organism: http://identifiers.org/taxonomy/559292
name: YCL011C
name: YCL11C
name: RLF6
name: Single-strand telomeric DNA-binding protein GBP2
name: RAP1 localization factor 6
name: GBP2

RelationshipXref interpro IPR019818
type: RelationshipXref
id: IPR019818
db: interpro

RelationshipXref uniprotkb D6VSQ9 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VSQ9
db: uniprot knowledgebase

RelationshipXref go GO 2000601
type: RelationshipXref
id: GO:2000601
db: gene ontology

Evidence 8e722545-2816-4979-82fe-49729aa75e02 IM-15332-5170 431225 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

Evidence 4782a379-455f-4eaa-b1b0-5cdf28da44c6 IM-15332-8811 431873 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm d782e4be-55bc-4ec6-b94e-78044a25fb74
type: ExperimentalForm
experimental feature: ModificationFeature 7ed04475-45d4-4b03-abd7-dd70d5ebfb40 430712
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 900839ad-7f0d-41f1-8937-6e91d89df093
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref imex IM-15332-8826 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-8826
db: imex

ExperimentalForm 2dc38ac8-f352-40dd-8072-bdff8c7b4d8b
type: ExperimentalForm
experimental feature: ModificationFeature 66fc0758-bf37-415a-b469-9d830c315091 430823
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpb9-spt5-1
type: MolecularInteraction
xref: UnificationXref mint MINT-2205096
xref: RelationshipXref intact EBI-7531438 identity
xref: RelationshipXref imex IM-15332-12883 imex-primary
evidence: Evidence f02683b0-f36c-486c-b369-499df8a1bec5 IM-15332-12883 432565 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 0.878564778330178
comment: comment:mint
comment: author-confidence:reliability score: 0.866
data source: intact
participant: Protein uniprotkb P27999 identity 1529029542686
participant: spt5_yeast

RelationshipXref go GO 0006635
type: RelationshipXref
id: GO:0006635
db: gene ontology

ExperimentalForm 94a20196-1aa9-4be9-ad09-2ba90a36f12a
type: ExperimentalForm
experimental feature: ModificationFeature 84872484-a757-43fa-bf02-e25cbce767c4 433731
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rgr1-srb5
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-5976 imex-primary
xref: UnificationXref mint MINT-2198114
xref: RelationshipXref intact EBI-7518441 identity
evidence: Evidence 3381c9a2-cdab-49f3-9795-8f8d93534ea5 IM-15332-5976 431025 430156
interaction type: physical association
comment: comment:mint
comment: author-confidence:reliability score: 0.733
comment: author-confidence:z-score: 3.44435096621864
data source: intact
participant: Protein uniprotkb P19263 identity 1529029541917
participant: Protein uniprotkb P32585 identity 1529029541916

RelationshipXref interpro IPR019805
type: RelationshipXref
id: IPR019805
db: interpro

RelationshipXref interpro IPR019804
type: RelationshipXref
id: IPR019804
db: interpro

RelationshipXref imex IM-15332-5578 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5578
db: imex

ExperimentalForm 877ca69f-ff5f-40e9-a0d6-de10dd44085e
type: ExperimentalForm
experimental feature: ModificationFeature 53abb7dc-c84d-41f7-9ede-63a899a11703 431743
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpb10-rpb3-3
type: MolecularInteraction
xref: RelationshipXref intact EBI-7525310 identity
xref: UnificationXref mint MINT-2202687
xref: RelationshipXref imex IM-15332-5589 imex-primary
evidence: Evidence 26f08cf2-9d19-4219-b9b0-ee23c1fa12ab IM-15332-5589 432041 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.944
comment: author-confidence:z-score: -0.0370333883826389
data source: intact
participant: rpb3_yeast
participant: rpab5_yeast

ExperimentalForm bf992503-7d95-4963-9749-73837c8df53d
type: ExperimentalForm
experimental feature: ModificationFeature 698d2b5a-7fe0-4a8a-bed2-9cf1e2109373 431615
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

Evidence d7718885-d01e-40e3-b44c-d45fa5fa2251 IM-15332-6379 432097 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref imex IM-15332-1583 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1583
db: imex

UnificationXref mint MINT-2197285
type: UnificationXref
id: MINT-2197285
db: mint

RelationshipXref go GO 0006623
type: RelationshipXref
id: GO:0006623
db: gene ontology

ExperimentalForm ae73347d-93c2-4a8f-90a2-23428dc818a0
type: ExperimentalForm
experimental feature: ModificationFeature 5b80a7f0-263c-4697-861e-9eb6f923fdbb 431104
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-17172 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-17172
db: intact

RelationshipXref imex IM-15332-3602 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-3602
db: imex

RelationshipXref intact EBI-7519530 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7519530
db: intact

RelationshipXref go GO 0005829 component
type: RelationshipXref
relationship type: MI:0354
id: GO:0005829
db: gene ontology

UnificationXref uniprot knowledgebase P38888
type: UnificationXref
id: P38888
db: uniprot knowledgebase

ExperimentalForm 31376304-8860-4016-83d6-fe052722cddb
type: ExperimentalForm
experimental feature: ModificationFeature 53a74add-abff-4599-9197-371442bc4b5e 431523
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpa49_yeast
type: Protein
evidence: Evidence b463a894-f92e-40b7-affe-ac8e75636a54 p 433206
entity reference: Q01080
name: DNA-directed RNA polymerase I subunit RPA49
comment: psi-mi participant
data source: intact

RelationshipXref go GO 0006612
type: RelationshipXref
id: GO:0006612
db: gene ontology

RelationshipXref go GO 0006610
type: RelationshipXref
id: GO:0006610
db: gene ontology

RelationshipXref interpro IPR023673
type: RelationshipXref
id: IPR023673
db: interpro

rfa3_yeast
type: Protein
evidence: Evidence 831b1de0-0600-48fc-9a88-e2d19d4846f9 p 430870
entity reference: P26755
name: Replication factor A protein 3
comment: psi-mi participant
data source: intact

rfa3_yeast
type: Protein
evidence: Evidence 8aaa94e2-8e01-4f50-8216-ba0647a87433 p 430867
entity reference: P26755
name: Replication factor A protein 3
comment: psi-mi participant
data source: intact

rfa3_yeast
type: Protein
evidence: Evidence e47b5e6f-7b85-4ffd-8d56-18f87c9f92ee p 430863
entity reference: P26755
name: Replication factor A protein 3
comment: psi-mi participant
data source: intact

rfa3_yeast
type: Protein
evidence: Evidence ec9c785c-40d5-4787-8ffc-1bafa13252b3 p 430858
entity reference: P26755
name: Replication factor A protein 3
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 2N3W
type: RelationshipXref
id: 2N3W
db: protein data bank

RelationshipXref rcsb pdb 2N3V
type: RelationshipXref
id: 2N3V
db: protein data bank

RelationshipXref rcsb pdb 2N3U
type: RelationshipXref
id: 2N3U
db: protein data bank

RelationshipXref rcsb pdb 2N3T
type: RelationshipXref
id: 2N3T
db: protein data bank

ret1-rpc82-1
type: MolecularInteraction
xref: RelationshipXref intact EBI-7515791 identity
xref: RelationshipXref imex IM-15332-7622 imex-primary
xref: UnificationXref mint MINT-2195916
evidence: Evidence 2ed1d785-d94e-4ad7-bd37-48d0281a547b IM-15332-7622 430537 430156
interaction type: physical association
comment: author-confidence:z-score: 6.50417611024389
comment: comment:homomint
comment: author-confidence:reliability score: 0.989
comment: comment:mint
data source: intact
participant: Protein uniprotkb P22276 identity 1529029541672
participant: Protein uniprotkb P32349 identity 1529029541673

UnificationXref uniprot knowledgebase Q01080
type: UnificationXref
id: Q01080
db: uniprot knowledgebase

UnificationXref uniprot knowledgebase Q02959
type: UnificationXref
id: Q02959
db: uniprot knowledgebase

RelationshipXref go GO 0006607
type: RelationshipXref
id: GO:0006607
db: gene ontology

RelationshipXref go GO 0006606
type: RelationshipXref
id: GO:0006606
db: gene ontology

RelationshipXref rcsb pdb 2MRI
type: RelationshipXref
id: 2MRI
db: protein data bank

RelationshipXref uniprotkb D6VZP9 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VZP9
db: uniprot knowledgebase

UnificationXref uniprot knowledgebase Q05775
type: UnificationXref
id: Q05775
db: uniprot knowledgebase

ExperimentalForm f2780466-8457-45d3-96bf-e5ebe7c36548
type: ExperimentalForm
experimental feature: ModificationFeature ab010816-ff5d-41f3-b602-16017b14c97f 433279
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref interpro IPR032914
type: RelationshipXref
id: IPR032914
db: interpro

Evidence 3a06e42f-e8c8-4c6a-9c69-eb77b8dd17bb IM-15332-8801 430881 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

Evidence a0b57758-637c-42c8-97d2-dbf82d74def5 IM-15332-5169 430813 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref mint P53942
type: RelationshipXref
id: P53942
db: mint

rfa3_yeast
type: Protein
evidence: Evidence a31674a4-a02b-4e56-b696-c6f0366b9c5c p 430850
entity reference: P26755
name: Replication factor A protein 3
comment: psi-mi participant
data source: intact

rfa3_yeast
type: Protein
evidence: Evidence a578f635-c2e2-4d05-8e72-10cb6481c610 p 430846
entity reference: P26755
name: Replication factor A protein 3
comment: psi-mi participant
data source: intact

rfa3_yeast
type: Protein
evidence: Evidence bcca8f3b-65aa-4af5-a3ce-61cc9e862fec p 430842
entity reference: P26755
name: Replication factor A protein 3
comment: psi-mi participant
data source: intact

Evidence 44e91521-6303-4e01-924d-1345383db733 IM-15332-9200 431497 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rfa3_yeast
type: Protein
evidence: Evidence 0fb37486-a942-49da-b7bd-1c6fce564731 p 430838
entity reference: P26755
name: Replication factor A protein 3
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 2MQW
type: RelationshipXref
id: 2MQW
db: protein data bank

rfa3_yeast
type: Protein
evidence: Evidence 5a4c0381-5043-4284-b5d2-fa67f000fe2d p 430834
entity reference: P26755
name: Replication factor A protein 3
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-12055 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12055
db: imex

UnificationXref mint MINT-2200112
type: UnificationXref
id: MINT-2200112
db: mint

rpa43_yeast
type: Protein
evidence: Evidence 9c25575f-c53c-4322-953c-9304d0d9e3f0 p 432758
entity reference: P46669
name: DNA-directed RNA polymerase I subunit RPA43
comment: psi-mi participant
data source: intact

ExperimentalForm 1754cd11-6574-4f5f-9878-8e04ccd2be86
type: ExperimentalForm
experimental feature: ModificationFeature 1ca9fde6-3e47-42af-a711-60a9bf77f3eb 430352
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rot2-gtb1-2
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-9200 imex-primary
xref: UnificationXref mint MINT-2200238
xref: RelationshipXref intact EBI-7521462 identity
evidence: Evidence 44e91521-6303-4e01-924d-1345383db733 IM-15332-9200 431497 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.99
comment: author-confidence:z-score: 0.32650412455981
data source: intact
participant: Protein uniprotkb P38138 identity 1529029542153
participant: Protein uniprotkb Q04924 identity 1529029542152

Evidence f02683b0-f36c-486c-b369-499df8a1bec5 IM-15332-12883 432565 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref intact EBI-15806 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-15806
db: intact

RelationshipXref go GO 0034599
type: RelationshipXref
id: GO:0034599
db: gene ontology

rfa3_yeast
type: Protein
evidence: Evidence cacc0d14-8f27-4ea2-8b4f-ce97240bd4ce p 430830
entity reference: P26755
name: Replication factor A protein 3
comment: psi-mi participant
data source: intact

rpab1_yeast
type: Protein
evidence: Evidence 23b68571-3f1f-4d1d-bbae-d21dead5ea73 p 431544
entity reference: rpab1_yeast
name: DNA-directed RNA polymerases I, II, and III subunit RPABC1
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2211164
type: UnificationXref
id: MINT-2211164
db: mint

UnificationXref uniprot knowledgebase Q12343
type: UnificationXref
id: Q12343
db: uniprot knowledgebase

UnificationXref uniprot knowledgebase Q12527
type: UnificationXref
id: Q12527
db: uniprot knowledgebase

RelationshipXref interpro IPR002205
type: RelationshipXref
id: IPR002205
db: interpro

rpc3_yeast
type: Protein
evidence: Evidence f27d5f9b-fbfc-46d4-8436-57942ecbff87 p 433142
entity reference: rpc3_yeast
name: DNA-directed RNA polymerase III subunit RPC3
comment: psi-mi participant
data source: intact

ExperimentalForm a55d9ac2-f2d8-4c0e-82d9-33b0d4966490
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

Evidence 04ec04ac-c9f0-4d8e-94f2-4a870647d552 IM-15332-12894 433685 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm 610e861c-bd5b-4e6e-807e-9ec313d01bd5
type: ExperimentalForm
experimental feature: ModificationFeature 71acd31b-83a5-47e2-aee4-5851af4fe319 431256
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpc31-rpc82
type: MolecularInteraction
xref: RelationshipXref intact EBI-7534035 identity
xref: UnificationXref mint MINT-2206429
xref: RelationshipXref imex IM-15332-3591 imex-primary
evidence: Evidence 475e3a5c-8cbb-453b-ac91-d1c73cf8e499 IM-15332-3591 432861 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.989
comment: author-confidence:z-score: 6.27908836047122
comment: comment:mint
data source: intact
participant: Protein uniprotkb P32349 identity 1529029542835
participant: rpc7_yeast

ExperimentalForm 49be85bf-ec0f-48f5-8e38-0504dbd87e66
type: ExperimentalForm
experimental feature: ModificationFeature 5d9d9ae2-6e49-4c46-8f16-16f1b8365156 431791
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref dip DIP-2303N identity
type: RelationshipXref
relationship type: MI:0356
id: DIP-2303N
db: database of interacting proteins

RelationshipXref imex IM-15332-11261 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-11261
db: imex

RelationshipXref imex IM-15332-3164 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-3164
db: imex

ExperimentalForm 34d16f59-acaa-4ad5-aab1-c67c7c7f9f0f
type: ExperimentalForm
experimental feature: ModificationFeature 2849b1fc-b7b4-4756-9a60-f23abc151188 432968
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-12065 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12065
db: imex

RelationshipXref intact EBI-7531454 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7531454
db: intact

UnificationXref mint MINT-2211146
type: UnificationXref
id: MINT-2211146
db: mint

RelationshipXref intact EBI-24256 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-24256
db: intact

ume1_yeast
type: ProteinReference
sequence: MSTLDIAEDNKIKNEEFKIWKKSIPSLYQHISSLKPIFGSGVDESPSTLRSIVFTNDSSCNKSKGVLSVPLLYSQGSEIFEVDCIVPLGLHYKKPESISEPLVQPDYTMESQKVEQTVLIPKWEFKGETIAKMIYVDNSEINVKVIALSTNGSLAWFREGVKSPVYTMMEPSTSLSSASSGNQNKPCVDFAISNDSKTLTVTKEKHLDNENATIKLIDNSGKIGEVLRTIPVPGIKNIQEIKFLNNQIFATCSDDGIIRFWGNEIGKKPLWILNDSLDGKTTCFAASPFVDTLFMTGTSGGALKVWDIRAVIALGDADAELNINQGHNKVNELFKVHHFYSEQVSKIEFSSISPMEVVTIGGLGNVYHWNFEPVFAIYNEIHEDFQGIISDELEAESMAFYHTEGCRREIGENNKVNTVAYHKYIEDLVATVDSDGLLTVYKPFTGKVLDGSREVGAAKS
xref: RelationshipXref go GO 0032221
xref: RelationshipXref uniprotkb P87330 secondary-ac
xref: RelationshipXref go GO 0005634
xref: RelationshipXref mint Q03010
xref: RelationshipXref go GO 0006325
xref: RelationshipXref go GO 0040020
xref: RelationshipXref uniprotkb D6W3M9 secondary-ac
xref: RelationshipXref go GO 0006351
xref: RelationshipXref refseq NP 015186 1
xref: RelationshipXref interpro IPR015943
xref: RelationshipXref dip DIP-5290N
xref: RelationshipXref go GO 0005737
xref: RelationshipXref go GO 0045944
xref: UnificationXref uniprot knowledgebase Q03010
xref: RelationshipXref go GO 0033698
xref: RelationshipXref interpro IPR036322
xref: RelationshipXref go GO 0051321
xref: RelationshipXref go GO 0003714
xref: RelationshipXref interpro IPR001680
xref: RelationshipXref intact EBI-20070 identity
xref: RelationshipXref go GO 0016479
xref: RelationshipXref go GO 0031939
xref: RelationshipXref sgd S000006060
organism: http://identifiers.org/taxonomy/559292
name: Transcriptional regulatory protein UME1
name: WD repeat-containing transcriptional modulator 3
name: LPI7C
name: UME1
name: WTM3
name: YPL139C

Evidence 646e6dbf-5ef0-4bf7-9228-6899b0a54012 IM-15332-12499 433453 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

Evidence 57f173bf-9448-4f98-b013-a95cf215225b IM-15332-8417 431929 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm a8c306bf-d646-44f7-8736-bbe08b7e6a7b
type: ExperimentalForm
experimental feature: ModificationFeature e113a1ea-b70a-4388-a511-f4ef28c69801 432912
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 1062b952-64cd-47a9-a4e3-1630e0217c86
type: ExperimentalForm
experimental feature: ModificationFeature 5e41574c-6e8f-4a7f-8a78-565b42be50d1 430764
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-4763 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-4763
db: imex

RelationshipXref intact EBI-7520334 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7520334
db: intact

rpb7_yeast
type: Protein
evidence: Evidence 0c92d7ea-fe0f-47fc-82e0-2594480fd871 p 431928
entity reference: rpb7_yeast
name: DNA-directed RNA polymerase II subunit RPB7
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7516789 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7516789
db: intact

tho2-hpr1-10
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-9199 imex-primary
xref: RelationshipXref intact EBI-7519379 identity
xref: UnificationXref mint MINT-2198888
evidence: Evidence bc05c948-12be-4da9-8300-a54c92e43c7f IM-15332-9199 431197 430156
interaction type: physical association
comment: author-confidence:z-score: -0.0172346410631702
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: hpr1_yeast
participant: Protein uniprotkb P53552 identity 1529029542003

RelationshipXref imex IM-15332-5602 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5602
db: imex

UnificationXref mint MINT-2206682
type: UnificationXref
id: MINT-2206682
db: mint

hxkb_yeast
type: ProteinReference
sequence: MVHLGPKKPQARKGSMADVPKELMQQIENFEKIFTVPTETLQAVTKHFISELEKGLSKKGGNIPMIPGWVMDFPTGKESGDFLAIDLGGTNLRVVLVKLGGDRTFDTTQSKYRLPDAMRTTQNPDELWEFIADSLKAFIDEQFPQGISEPIPLGFTFSFPASQNKINEGILQRWTKGFDIPNIENHDVVPMLQKQITKRNIPIEVVALINDTTGTLVASYYTDPETKMGVIFGTGVNGAYYDVCSDIEKLQGKLSDDIPPSAPMAINCEYGSFDNEHVVLPRTKYDITIDEESPRPGQQTFEKMSSGYYLGEILRLALMDMYKQGFIFKNQDLSKFDKPFVMDTSYPARIEEDPFENLEDTDDLFQNEFGINTTVQERKLIRRLSELIGARAARLSVCGIAAICQKRGYKTGHIAADGSVYNRYPGFKEKAANALKDIYGWTQTSLDDYPIKIVPAEDGSGAGAAVIAALAQKRIAEGKSVGIIGA
xref: RelationshipXref refseq NP 011261 1
xref: RelationshipXref go GO 0001678
xref: RelationshipXref go GO 0001302
xref: RelationshipXref go GO 0005524
xref: RelationshipXref go GO 0006006
xref: RelationshipXref reactome R-SCE-6798695
xref: RelationshipXref go GO 0006000
xref: RelationshipXref mint P04807
xref: RelationshipXref go GO 0032445
xref: RelationshipXref go GO 0006096
xref: RelationshipXref rcsb pdb 5UWT
xref: RelationshipXref go GO 0005829
xref: RelationshipXref dip DIP-2380N
xref: RelationshipXref go GO 0019158
xref: RelationshipXref rcsb pdb 1IG8
xref: RelationshipXref reactome R-SCE-170822
xref: RelationshipXref go GO 0004340
xref: RelationshipXref go GO 0046323
xref: RelationshipXref go GO 0046015
xref: RelationshipXref interpro IPR022673
xref: RelationshipXref interpro IPR022672
xref: RelationshipXref reactome R-SCE-70171
xref: RelationshipXref rcsb pdb 2YHX
xref: RelationshipXref uniprotkb D6VV82 secondary-ac
xref: RelationshipXref go GO 0008865
xref: RelationshipXref go GO 0005536
xref: RelationshipXref go GO 0004396
xref: RelationshipXref uniprotkb Q05838 secondary-ac
xref: RelationshipXref intact EBI-8738 identity
xref: RelationshipXref go GO 0005739
xref: RelationshipXref go GO 0006013
xref: RelationshipXref interpro IPR019807
xref: UnificationXref uniprot knowledgebase P04807
xref: RelationshipXref go GO 0005634
xref: RelationshipXref sgd S000003222
xref: RelationshipXref interpro IPR001312
organism: http://identifiers.org/taxonomy/559292
name: HXK2
name: NRB486
name: Hexokinase-B
name: YGL253W
name: HEX1
name: HKB
name: Hexokinase PII
name: Hexokinase-2

rpb10-rpc53
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-2352 imex-primary
xref: UnificationXref mint MINT-2202291
xref: RelationshipXref intact EBI-7524524 identity
evidence: Evidence 9516879c-edb6-4205-a66b-9d1074db0d66 IM-15332-2352 431953 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: -0.0816125864286376
comment: author-confidence:reliability score: 0.77
comment: comment:mint
data source: intact
participant: Protein uniprotkb P25441 identity 1529029542380
participant: rpab5_yeast

UnificationXref mint MINT-2211128
type: UnificationXref
id: MINT-2211128
db: mint

ret1-rpc34-1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-10019 imex-primary
xref: RelationshipXref intact EBI-7515677 identity
xref: UnificationXref mint MINT-2195826
evidence: Evidence 840f4fb8-449c-4ac2-97b6-bf64ac3a5488 IM-15332-10019 430517 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 9.09697412858283
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P22276 identity 1529029541662
participant: rpc6_yeast

ExperimentalForm 1224e6ea-819e-40c5-91e0-c9113ed97685
type: ExperimentalForm
experimental feature: ModificationFeature 2ad4b165-cca1-42d6-8ff7-2938e7fbfe73 430891
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

UnificationXref mint MINT-2200166
type: UnificationXref
id: MINT-2200166
db: mint

RelationshipXref interpro IPR000268
type: RelationshipXref
id: IPR000268
db: interpro

UnificationXref mint MINT-2206664
type: UnificationXref
id: MINT-2206664
db: mint

ExperimentalForm 831fbba3-f0db-4c0d-b17a-79ac26d38ef4
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7518156 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7518156
db: intact

RelationshipXref intact EBI-7516885 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7516885
db: intact

rir3_yeast
type: Protein
evidence: Evidence 584b5300-a9d7-4356-8abe-2db95cc42cdc p 431432
entity reference: rir3_yeast
name: Ribonucleoside-diphosphate reductase large chain 2
comment: psi-mi participant
data source: intact

RelationshipXref dip DIP-4693N
type: RelationshipXref
id: DIP-4693N
db: database of interacting proteins

ExperimentalForm c42312c5-e345-4a90-9197-176fdd5e2455
type: ExperimentalForm
experimental feature: ModificationFeature 6f1f0753-1d39-448d-8dfa-f43240a94333 431819
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

UnificationXref mint MINT-2195988
type: UnificationXref
id: MINT-2195988
db: mint

RelationshipXref refseq NP 009378 1
type: RelationshipXref
id: NP_009378.1
db: refseq

ExperimentalForm ce13c583-8178-451a-9256-2112bceb2581
type: ExperimentalForm
experimental feature: ModificationFeature a3e6c2bc-21b0-43da-89b1-54e466611f45 433871
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref rcsb pdb 1QZR
type: RelationshipXref
id: 1QZR
db: protein data bank

rpc19-ret1-3
type: MolecularInteraction
xref: RelationshipXref intact EBI-7533218 identity
xref: RelationshipXref imex IM-15332-3993 imex-primary
xref: UnificationXref mint MINT-2206267
evidence: Evidence 3cb2912f-707d-4e87-92c4-27df459d8ca9 IM-15332-3993 432825 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 1.40294581165597
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P22276 identity 1529029542817
participant: rpac2_yeast

UnificationXref mint MINT-2200184
type: UnificationXref
id: MINT-2200184
db: mint

RelationshipXref imex IM-15332-7191 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-7191
db: imex

RelationshipXref intact EBI-7525432 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7525432
db: intact

reb1-pkh1
type: MolecularInteraction
xref: UnificationXref mint MINT-2195429
xref: RelationshipXref imex IM-15332-12471 imex-primary
xref: RelationshipXref intact EBI-7515299 identity
evidence: Evidence dbf8a77c-0c52-4c15-8332-44a62c0844bd IM-15332-12471 430429 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.367
comment: comment:mint
comment: author-confidence:z-score: 0.190545304399868
data source: intact
participant: Protein uniprotkb P21538 identity 1529029541618
participant: pkh1_yeast

rpg1-tif34-2
type: MolecularInteraction
xref: UnificationXref mint MINT-2209382
xref: RelationshipXref intact EBI-7539786 identity
xref: RelationshipXref imex IM-15332-1598 imex-primary
evidence: Evidence f533d116-a958-4a01-8010-152fdcb0698b IM-15332-1598 433517 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 1.30092684992045
comment: comment:mint
comment: author-confidence:reliability score: 0.972
data source: intact
participant: eif3a_yeast
participant: Protein uniprotkb P40217 identity 1529029543163

RelationshipXref interpro IPR000286
type: RelationshipXref
id: IPR000286
db: interpro

UnificationXref mint MINT-2195970
type: UnificationXref
id: MINT-2195970
db: mint

UnificationXref mint MINT-2206646
type: UnificationXref
id: MINT-2206646
db: mint

ExperimentalForm b737e6e0-de8e-426c-8cab-cca1595d4d36
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm f65a25d6-fbe0-401e-ac44-6c6249d30d91
type: ExperimentalForm
experimental feature: ModificationFeature 93982a5f-eb71-49e8-b6bc-5138555d6590 430479
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref uniprotkb D6VWF6 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VWF6
db: uniprot knowledgebase

UnificationXref mint MINT-2205295
type: UnificationXref
id: MINT-2205295
db: mint

RelationshipXref imex IM-15332-5191 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5191
db: imex

RelationshipXref mint Q04199
type: RelationshipXref
id: Q04199
db: mint

RelationshipXref uniprotkb D6VTB7 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VTB7
db: uniprot knowledgebase

RelationshipXref go GO 0034515
type: RelationshipXref
id: GO:0034515
db: gene ontology

UnificationXref uniprot knowledgebase P53549
type: UnificationXref
id: P53549
db: uniprot knowledgebase

Evidence 5fc87159-b581-459e-828f-c3677e48e5b4 IM-15332-2734 430697 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref go GO 0034511
type: RelationshipXref
id: GO:0034511
db: gene ontology

Evidence d9f8d278-9105-40fe-877d-7190eb6ea828 IM-15332-2748 432193 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref intact EBI-7514968 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7514968
db: intact

RelationshipXref uniprotkb D6VUW9 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VUW9
db: uniprot knowledgebase

ret2-cop1-3
type: MolecularInteraction
xref: RelationshipXref intact EBI-7515973 identity
xref: RelationshipXref imex IM-15332-3156 imex-primary
xref: UnificationXref mint MINT-2196096
evidence: Evidence cb5444e8-1e48-423b-ba42-4b39137ae8cc IM-15332-3156 430577 430156
interaction type: physical association
comment: author-confidence:z-score: 2.20702802763729
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P43621 identity 1529029541693
participant: Protein uniprotkb P53622 identity 1529029541692

Evidence e2908040-10f9-4902-88a2-dfffcbc17756 IM-15332-7654 433777 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref uniprot knowledgebase Q12451
type: UnificationXref
id: Q12451
db: uniprot knowledgebase

Evidence e3dcba08-ad22-42ba-8e4c-5d92a5f69a5d IM-15332-8425 432881 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref go GO 0034503
type: RelationshipXref
id: GO:0034503
db: gene ontology

UnificationXref mint MINT-2206628
type: UnificationXref
id: MINT-2206628
db: mint

RelationshipXref go GO 0034501
type: RelationshipXref
id: GO:0034501
db: gene ontology

Evidence 33db6f8a-5205-4301-9d47-e50791561f37 IM-15332-12480 431305 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ret2-sec27-4
type: MolecularInteraction
xref: RelationshipXref intact EBI-7516181 identity
xref: UnificationXref mint MINT-2196294
xref: RelationshipXref imex IM-15332-5971 imex-primary
evidence: Evidence 44972dd8-6bd4-4f8f-845d-b42aed3bef30 IM-15332-5971 430621 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.99
comment: author-confidence:z-score: 1.78081071833074
data source: intact
participant: Protein uniprotkb P43621 identity 1529029541715
participant: Protein uniprotkb P41811 identity 1529029541714

RelationshipXref imex IM-15332-808 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-808
db: imex

RelationshipXref intact EBI-7531569 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7531569
db: intact

RelationshipXref intact EBI-15777 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-15777
db: intact

UnificationXref mint MINT-2205277
type: UnificationXref
id: MINT-2205277
db: mint

UnificationXref mint MINT-2202903
type: UnificationXref
id: MINT-2202903
db: mint

RelationshipXref imex IM-15332-12875 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12875
db: imex

ExperimentalForm 73ff4709-1fcf-4f40-8ebc-7d0d90b2ffe1
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref mint MINT-2206610
type: UnificationXref
id: MINT-2206610
db: mint

ExperimentalForm 9f35a804-0436-4ed4-906b-517b887d00c4
type: ExperimentalForm
experimental feature: ModificationFeature fa8fade8-8175-4f75-b44f-14773c727d05 433867
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

UnificationXref mint MINT-2195934
type: UnificationXref
id: MINT-2195934
db: mint

rfa3-rfa1-3
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-387 imex-primary
xref: UnificationXref mint MINT-2197285
xref: RelationshipXref intact EBI-7517369 identity
evidence: Evidence 81fd3b2a-ee35-420a-8f74-8da72329c6d2 IM-15332-387 430841 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.988
comment: author-confidence:z-score: 6.37356980528992
comment: comment:mint
data source: intact
participant: rfa3_yeast
participant: rfa1_yeast

rpc6_yeast
type: Protein
evidence: Evidence df90a36a-f8f4-4b6c-90e3-7464c492ff82 p 433030
entity reference: P32910
name: DNA-directed RNA polymerase III subunit RPC6
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-15730 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-15730
db: intact

RelationshipXref interpro IPR013860
type: RelationshipXref
id: IPR013860
db: interpro

rpab5_yeast
type: Protein
evidence: Evidence d9acc184-64fd-45c4-98ee-b56217cf06a0 p 431987
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

rpab5_yeast
type: Protein
evidence: Evidence a607a59f-7e78-49f0-9dd1-c5e632cb4a3c p 431983
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

rpac2_yeast
type: Protein
evidence: Evidence f6dfbbc8-a415-4733-914d-73fc0df34a56 p 431838
entity reference: P28000
name: DNA-directed RNA polymerases I and III subunit RPAC2
comment: psi-mi participant
data source: intact

rpab5_yeast
type: Protein
evidence: Evidence f1d7f8e9-eb7e-4bf3-ac4e-e01264a37709 p 431979
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

rpab5_yeast
type: Protein
evidence: Evidence 2f4c165c-a474-4241-a2c3-c310513cc257 p 431974
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

eaf3_yeast
type: Protein
evidence: Evidence 7308888f-67ae-475d-8967-6b9a8da7fceb p 430406
entity reference: Q12432
name: Chromatin modification-related protein EAF3
comment: psi-mi participant
data source: intact

rpa14-rpa43-4
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-8413 imex-primary
xref: UnificationXref mint MINT-2200616
xref: RelationshipXref intact EBI-7522138 identity
evidence: Evidence aea7b04a-813c-4afe-badf-37a803ff357d IM-15332-8413 431581 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.989
comment: author-confidence:z-score: 9.32197881825899
comment: comment:mint
data source: intact
participant: rpa43_yeast
participant: Protein uniprotkb P50106 identity 1529029542194

UnificationXref mint MINT-2202921
type: UnificationXref
id: MINT-2202921
db: mint

eaf3_yeast
type: Protein
evidence: Evidence d9211b4a-18aa-4243-a1c0-29c14d929863 p 430398
entity reference: Q12432
name: Chromatin modification-related protein EAF3
comment: psi-mi participant
data source: intact

rpb10-tfg2-1
type: MolecularInteraction
xref: UnificationXref mint MINT-2203065
xref: RelationshipXref imex IM-15332-9609 imex-primary
xref: RelationshipXref intact EBI-7525915 identity
evidence: Evidence 9d0a4004-8ee1-402a-9987-fe55e83a33a3 IM-15332-9609 432125 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.989
comment: author-confidence:z-score: 8.07010200910615
comment: comment:mint
data source: intact
participant: rpab5_yeast
participant: t2fb_yeast

Evidence aa230fb6-f951-4dbd-bef5-13b67e1195c8 IM-15332-1955 432065 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref refseq NP 010959 2
type: RelationshipXref
id: NP_010959.2
db: refseq

rpb11-rpb2-1
type: MolecularInteraction
xref: UnificationXref mint MINT-2203353
xref: RelationshipXref imex IM-15332-2355 imex-primary
xref: RelationshipXref intact EBI-7526730 identity
evidence: Evidence 6fa6b39d-2609-43eb-8ffc-c80ad594df23 IM-15332-2355 432189 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.988
comment: comment:mint
comment: author-confidence:z-score: 4.41215500557125
data source: intact
participant: Protein uniprotkb P38902 identity 1529029542498
participant: Protein uniprotkb P08518 identity 1529029542499

RelationshipXref refseq NP 014311 3
type: RelationshipXref
id: NP_014311.3
db: refseq

RelationshipXref rcsb pdb 1IJF
type: RelationshipXref
id: 1IJF
db: protein data bank

RelationshipXref rcsb pdb 1IJE
type: RelationshipXref
id: 1IJE
db: protein data bank

rpab5_yeast
type: Protein
evidence: Evidence d2b79863-900c-4b2d-995a-f67dc35e004f p 431967
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

rpab5_yeast
type: Protein
evidence: Evidence 61916602-a6db-4544-89d8-8a9190515bf5 p 431962
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

rpab5_yeast
type: Protein
evidence: Evidence 83957f11-b1a8-4a10-ab12-a7ba5811c9a8 p 431959
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

rpab5_yeast
type: Protein
evidence: Evidence fab4d78a-2d8b-4b3d-b104-9314cf443a22 p 431955
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

ExperimentalForm 6b9913b4-2743-460a-b4c5-28b845798e9a
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpb10-rpa43
type: MolecularInteraction
xref: UnificationXref mint MINT-2202255
xref: RelationshipXref imex IM-15332-7200 imex-primary
xref: RelationshipXref intact EBI-7524474 identity
evidence: Evidence 2486816d-30ee-41a3-9da0-946a7862e3a9 IM-15332-7200 431945 430156
interaction type: physical association
comment: author-confidence:z-score: 3.04164154595021
comment: comment:mint
comment: author-confidence:reliability score: 0.939
data source: intact
participant: rpa43_yeast
participant: rpab5_yeast

UnificationXref mint MINT-2195916
type: UnificationXref
id: MINT-2195916
db: mint

RelationshipXref intact EBI-7519310 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7519310
db: intact

UnificationXref mint MINT-2202939
type: UnificationXref
id: MINT-2202939
db: mint

RelationshipXref mint P38111
type: RelationshipXref
id: P38111
db: mint

RelationshipXref imex IM-15332-1955 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1955
db: imex

rpab5_yeast
type: Protein
evidence: Evidence 0ae92883-492e-42a4-a929-35301d41eb97 p 431947
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

rpab5_yeast
type: Protein
evidence: Evidence 9d87b28c-f786-46c4-b04d-6099be5e389b p 431942
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

rpab5_yeast
type: Protein
evidence: Evidence e38d9859-a807-4ceb-8825-21c01ea96618 p 431938
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7522027 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7522027
db: intact

rfa2-rfa1-6
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-9195 imex-primary
xref: RelationshipXref intact EBI-7517054 identity
xref: UnificationXref mint MINT-2196978
evidence: Evidence 4b239f39-6f81-41c3-b68e-a4c8e979e2d9 IM-15332-9195 430773 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 5.21976801105693
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: rfa2_yeast
participant: rfa1_yeast

RelationshipXref dip DIP-4325N
type: RelationshipXref
id: DIP-4325N
db: database of interacting proteins

RelationshipXref imex IM-15332-2759 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-2759
db: imex

ExperimentalForm a3d2b323-137c-413a-84b4-b849d1b23395
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

Evidence 925d9bdc-6946-4b62-b8c8-5653d0c30f44 IM-15332-6367 431117 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpab5_yeast
type: Protein
evidence: Evidence 74dd7618-fea5-441b-a760-23300eb2d4b2 p 431931
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

UnificationXref uniprot knowledgebase P39960
type: UnificationXref
id: P39960
db: uniprot knowledgebase

ExperimentalForm 7dd17e22-7e47-4c77-bdf0-49b2dff87382
type: ExperimentalForm
experimental feature: ModificationFeature d1ee416e-c643-4aba-8a70-0430c80118b7 431115
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 9c1859b3-5b67-410f-b697-defc54527c75
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7538985 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7538985
db: intact

RelationshipXref reactome R-SCE-6782135
type: RelationshipXref
id: R-SCE-6782135
db: reactome

rpab5_yeast
type: Protein
evidence: Evidence 750684c2-c79d-44bb-86c3-c07d5e3598bc p 431915
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

rpa43-rpa135-1
type: MolecularInteraction
xref: RelationshipXref intact EBI-7523722 identity
xref: RelationshipXref imex IM-15332-4776 imex-primary
xref: UnificationXref mint MINT-2201732
evidence: Evidence b7a36b26-75d5-44d8-9f7b-058a9ae9bb09 IM-15332-4776 431829 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.988
comment: author-confidence:z-score: 2.68603265427831
comment: comment:mint
data source: intact
participant: Protein uniprotkb P46669 identity 1529029542318
participant: Protein uniprotkb P22138 identity 1529029542319

UnificationXref mint MINT-2205223
type: UnificationXref
id: MINT-2205223
db: mint

UnificationXref mint MINT-2202957
type: UnificationXref
id: MINT-2202957
db: mint

RelationshipXref refseq NP 013866 1
type: RelationshipXref
id: NP_013866.1
db: refseq

RelationshipXref mint P38138
type: RelationshipXref
id: P38138
db: mint

RelationshipXref refseq NP 010706 identity
type: RelationshipXref
relationship type: MI:0356
id: NP_010706
db: refseq

RelationshipXref intact EBI-7517138 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7517138
db: intact

ExperimentalForm 56045a81-040d-4fb8-88a2-4d85c6957a40
type: ExperimentalForm
experimental feature: ModificationFeature 4803627c-f8f1-4807-a5f0-2e1796e02682 431367
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpn11_yeast
type: Protein
evidence: Evidence 45addc98-a901-44e4-a6ab-e0b8a0490fb4 p 433908
entity reference: P43588
name: Ubiquitin carboxyl-terminal hydrolase RPN11
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-5182 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5182
db: imex

rpab5_yeast
type: Protein
evidence: Evidence 706b1386-f7cb-4017-b641-95298a84d988 p 431899
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

rpn11_yeast
type: Protein
evidence: Evidence ff4a1084-bd4c-4b2c-98e5-eb47ad1bee87 p 433900
entity reference: P43588
name: Ubiquitin carboxyl-terminal hydrolase RPN11
comment: psi-mi participant
data source: intact

rnr1-rnr3-16
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-6372 imex-primary
xref: RelationshipXref intact EBI-7521029 identity
xref: UnificationXref mint MINT-2199932
evidence: Evidence 169a3aec-ca45-4381-bb07-b74fa5a34cf3 IM-15332-6372 431429 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.906
comment: comment:homomint
comment: comment:mint
comment: author-confidence:z-score: 0.301980829083214
data source: intact
participant: rir3_yeast
participant: Protein uniprotkb P21524 identity 1529029542118

rpab5_yeast
type: Protein
evidence: Evidence 09c52f46-7d17-4296-8a2d-a1c0484a060f p 431894
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

Evidence 4ee5d439-6513-46a7-847a-8896cf1dd505 IM-15332-9604 431501 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref imex IM-15332-10445 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-10445
db: imex

rpn1-rpn8-3
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-12501 imex-primary
xref: RelationshipXref intact EBI-7542660 identity
xref: UnificationXref mint MINT-2210660
evidence: Evidence c1af0e33-f884-4eb2-ba34-cf2ac9e6fd53 IM-15332-12501 433801 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.99
comment: author-confidence:z-score: 1.29403844027237
data source: intact
participant: rpn8_yeast
participant: Protein uniprotkb P38764 identity 1529029543304

RelationshipXref rcsb pdb 1IG8
type: RelationshipXref
id: 1IG8
db: protein data bank

RelationshipXref intact EBI-7516853 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7516853
db: intact

Evidence c6de6544-fe52-4a4a-8572-f8cf2ba5de95 IM-15332-408 433289 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref imex IM-15332-11249 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-11249
db: imex

UnificationXref mint MINT-2209130
type: UnificationXref
id: MINT-2209130
db: mint

Evidence aefba991-11f8-4bb1-8de6-c837e95b87e0 IM-15332-1577 431133 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpab5_yeast
type: Protein
evidence: Evidence 3959f5d0-f852-4ec2-8bdf-2379188581e3 p 431891
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

rpab5_yeast
type: Protein
evidence: Evidence d8c71152-9a32-4a5a-a509-5787801ededa p 431886
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

rpab5_yeast
type: Protein
evidence: Evidence 5cd894ab-fb5e-4936-b46d-8d273a3aa7b9 p 431882
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

rpab5_yeast
type: Protein
evidence: Evidence 34e069bb-e703-4322-9114-e83b1f26fbed p 431879
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

ExperimentalForm cb360d55-63f6-44ef-8522-28b3c4f4995b
type: ExperimentalForm
experimental feature: ModificationFeature 1caa95e1-47d8-4f71-a629-2f469def0813 432156
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpab5_yeast
type: Protein
evidence: Evidence efffa8fc-b2d3-4d1f-9f36-974300840ec2 p 431874
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2202975
type: UnificationXref
id: MINT-2202975
db: mint

RelationshipXref rcsb pdb 4U4Y
type: RelationshipXref
id: 4U4Y
db: protein data bank

RelationshipXref rcsb pdb 4U56
type: RelationshipXref
id: 4U56
db: protein data bank

RelationshipXref interpro IPR037138
type: RelationshipXref
id: IPR037138
db: interpro

RelationshipXref rcsb pdb 4U4Q
type: RelationshipXref
id: 4U4Q
db: protein data bank

RelationshipXref rcsb pdb 4U51
type: RelationshipXref
id: 4U51
db: protein data bank

RelationshipXref rcsb pdb 4U4O
type: RelationshipXref
id: 4U4O
db: protein data bank

RelationshipXref rcsb pdb 4U4N
type: RelationshipXref
id: 4U4N
db: protein data bank

rpab5_yeast
type: Protein
evidence: Evidence 67144047-9a34-46d3-bcfa-edc838c5980e p 431871
entity reference: P22139
name: DNA-directed RNA polymerases I, II, and III subunit RPABC5
comment: psi-mi participant
data source: intact

ExperimentalForm 96355671-0a82-4cd8-b7e5-b317409707de
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref mint P42073
type: RelationshipXref
id: P42073
db: mint

ExperimentalForm f2aa5009-8bc0-41d4-bd78-53ab470e7edc
type: ExperimentalForm
experimental feature: ModificationFeature ef0cd50a-0997-43d3-9226-b0b3a0204fa7 433460
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref rcsb pdb 4U3U
type: RelationshipXref
id: 4U3U
db: protein data bank

RelationshipXref intact EBI-6933345 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-6933345
db: intact

UnificationXref uniprot knowledgebase P39927
type: UnificationXref
id: P39927
db: uniprot knowledgebase

RelationshipXref imex IM-15332-802 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-802
db: imex

RelationshipXref rcsb pdb 4U3N
type: RelationshipXref
id: 4U3N
db: protein data bank

RelationshipXref rcsb pdb 4U3M
type: RelationshipXref
id: 4U3M
db: protein data bank

RelationshipXref imex IM-15332-6370 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-6370
db: imex

RelationshipXref intact EBI-7539832 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7539832
db: intact

RelationshipXref imex IM-15332-11633 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-11633
db: imex

RelationshipXref interpro IPR019787
type: RelationshipXref
id: IPR019787
db: interpro

RelationshipXref interpro IPR019786
type: RelationshipXref
id: IPR019786
db: interpro

UnificationXref mint MINT-2202993
type: UnificationXref
id: MINT-2202993
db: mint

Evidence b04f3320-2bc0-4b2c-9635-85a81da1c8d5 IM-15332-1216 432005 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref rcsb pdb 1ID3
type: RelationshipXref
id: 1ID3
db: protein data bank

ExperimentalForm 50dba8d7-82ea-498b-9c20-d469cc82cf1e
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpn1-rpt2-11
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-11650 imex-primary
xref: UnificationXref mint MINT-2210282
xref: RelationshipXref intact EBI-7541926 identity
evidence: Evidence b372ffa8-5024-4ca0-b0fe-09d0a9ff667d IM-15332-11650 433717 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.99
comment: author-confidence:z-score: 1.80302229752703
data source: intact
participant: Protein uniprotkb P38764 identity 1529029543262
participant: prs4_yeast

rpab2_yeast
type: Protein
evidence: Evidence 9b1cc964-2797-4f7c-818f-299d5bcb0a51 p 432110
entity reference: rpab2_yeast
name: DNA-directed RNA polymerases I, II, and III subunit RPABC2
comment: psi-mi participant
data source: intact

ExperimentalForm aba41f04-59af-4985-96ac-22db3d0533cb
type: ExperimentalForm
experimental feature: ModificationFeature dda7cdb8-3a54-4711-9e60-fb1047f20b92 431279
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ret2-sec26-4
type: MolecularInteraction
xref: RelationshipXref intact EBI-7516054 identity
xref: UnificationXref mint MINT-2196150
xref: RelationshipXref imex IM-15332-2732 imex-primary
evidence: Evidence 14a09b12-f911-4962-bfb7-8febe6319595 IM-15332-2732 430589 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.976
comment: comment:mint
comment: author-confidence:z-score: 2.44334076304923
data source: intact
participant: Protein uniprotkb P43621 identity 1529029541699
participant: Protein uniprotkb P41810 identity 1529029541698

rpn11_yeast
type: Protein
evidence: Evidence 20c4f05b-fbbf-4206-9e9e-f2d778d23f64 p 433824
entity reference: P43588
name: Ubiquitin carboxyl-terminal hydrolase RPN11
comment: psi-mi participant
data source: intact

RelationshipXref sgd S000000299
type: RelationshipXref
id: S000000299
db: sgd

RelationshipXref interpro IPR019775
type: RelationshipXref
id: IPR019775
db: interpro

RelationshipXref intact EBI-7538408 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7538408
db: intact

RelationshipXref sgd S000000291
type: RelationshipXref
id: S000000291
db: sgd

RelationshipXref intact EBI-15745 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-15745
db: intact

rpg1-tif5-4
type: MolecularInteraction
xref: UnificationXref mint MINT-2209418
xref: RelationshipXref intact EBI-7539848 identity
xref: RelationshipXref imex IM-15332-3997 imex-primary
evidence: Evidence 4a93cfe4-e948-45d1-a102-3383d0113357 IM-15332-3997 433525 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 2.42802749713117
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P38249 identity 1529029543167
participant: Protein uniprotkb P38431 identity 1529029543166

RelationshipXref intact EBI-7516359 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7516359
db: intact

RelationshipXref rcsb pdb 4U1F
type: RelationshipXref
id: 4U1F
db: protein data bank

RelationshipXref rcsb pdb 4U1E
type: RelationshipXref
id: 4U1E
db: protein data bank

RelationshipXref rcsb pdb 4U1D
type: RelationshipXref
id: 4U1D
db: protein data bank

RelationshipXref uniprotkb Q03128 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: Q03128
db: uniprot knowledgebase

RelationshipXref intact EBI-7539848 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7539848
db: intact

RelationshipXref interpro IPR019761
type: RelationshipXref
id: IPR019761
db: interpro

ExperimentalForm fb6a2b86-05ff-426f-afed-fd624d6f22d8
type: ExperimentalForm
experimental feature: ModificationFeature 15ed6366-c0d5-4bd7-a13b-f6f56013f073 432808
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm fa1352a7-abf8-40dc-ac1d-3c4fdb0bef65
type: ExperimentalForm
experimental feature: ModificationFeature f1667fb9-f884-4a79-9a31-ce343dc9245a 433635
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref sgd S000001627
type: RelationshipXref
id: S000001627
db: sgd

RelationshipXref imex IM-15332-6380 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-6380
db: imex

rfc5_yeast
type: Protein
evidence: Evidence 603f787e-a715-4028-a086-3c2813b27df8 p 430948
entity reference: P38251
name: Replication factor C subunit 5
comment: psi-mi participant
data source: intact

RelationshipXref uniprotkb D3DL07 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D3DL07
db: uniprot knowledgebase

RelationshipXref intact EBI-17160 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-17160
db: intact

RelationshipXref imex IM-15332-11643 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-11643
db: imex

ExperimentalForm 4d2e6d53-e835-4dfd-844b-3e487a0002e9
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

Evidence a31ee8f9-a09a-4daa-8de6-0705da4a516f IM-15332-8028 433041 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref sgd S000000276
type: RelationshipXref
id: S000000276
db: sgd

UnificationXref molecular interactions ontology MI 0498
type: UnificationXref
id: MI:0498
db: molecular interactions ontology

rpn1-rpn12-7
type: MolecularInteraction
xref: RelationshipXref intact EBI-7542880 identity
xref: UnificationXref mint MINT-2210768
xref: RelationshipXref imex IM-15332-414 imex-primary
evidence: Evidence 04cb1c6f-822f-4c80-adbc-4f45c43f8650 IM-15332-414 433825 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.983
comment: author-confidence:z-score: 7.33102151736649
comment: comment:mint
data source: intact
participant: Protein uniprotkb P32496 identity 1529029543317
participant: Protein uniprotkb P38764 identity 1529029543316

rfc1-rfc3-2
type: MolecularInteraction
xref: UnificationXref mint MINT-2197484
xref: RelationshipXref intact EBI-7517580 identity
xref: RelationshipXref imex IM-15332-4764 imex-primary
evidence: Evidence 48692d66-7032-4d71-ab8d-391831fe1251 IM-15332-4764 430885 430156
interaction type: physical association
comment: author-confidence:z-score: 3.34005871809735
comment: comment:homomint
comment: author-confidence:reliability score: 0.989
comment: comment:mint
data source: intact
participant: Protein uniprotkb P38630 identity 1529029541846
participant: Protein uniprotkb P38629 identity 1529029541847

UnificationXref uniprot knowledgebase P22336
type: UnificationXref
id: P22336
db: uniprot knowledgebase

ExperimentalForm 7bc40f2e-220d-4501-a56a-de8c89cec72f
type: ExperimentalForm
experimental feature: ModificationFeature 89496a83-d59d-4664-8993-22aa391d1036 431444
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-9201 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-9201
db: imex

ExperimentalForm c1b4ebf5-0bd9-4fdf-8d76-8ac93f34374e
type: ExperimentalForm
experimental feature: ModificationFeature bb2dce7d-e9df-4ef4-b2ae-d6edcb2f6660 432984
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rnr1-rnr3-10
type: MolecularInteraction
xref: RelationshipXref intact EBI-7520779 identity
xref: RelationshipXref imex IM-15332-6371 imex-primary
xref: UnificationXref mint MINT-2199770
evidence: Evidence 648bd894-bd63-419f-b53d-fe8ae7462997 IM-15332-6371 431393 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.906
comment: comment:homomint
comment: author-confidence:z-score: 0.270198303527388
comment: comment:mint
data source: intact
participant: Protein uniprotkb P21524 identity 1529029542100
participant: Protein uniprotkb P21672 identity 1529029542101

Evidence 1f9afc66-9b6d-4c7d-9e10-775f1db7a87e IM-15332-3161 431253 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpn9_yeast
type: Protein
evidence: Evidence 3f44e288-fbd1-4a58-9efa-3fcbe7bf6a83 p 433678
entity reference: Q04062
name: 26S proteasome regulatory subunit RPN9
comment: psi-mi participant
data source: intact

rfc5_yeast
type: Protein
evidence: Evidence a0bd801a-27a3-47cf-9ee1-79841b9ca8ee p 430914
entity reference: P38251
name: Replication factor C subunit 5
comment: psi-mi participant
data source: intact

RelationshipXref mint P38922
type: RelationshipXref
id: P38922
db: mint

ExperimentalForm e4c8864f-f900-4dd5-bbbb-2e4226a77ac5
type: ExperimentalForm
experimental feature: ModificationFeature cc16ea1a-87e5-4354-97ca-a79b668dadcb 431531
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpa190-rpa49-2
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-10435 imex-primary
xref: UnificationXref mint MINT-2200814
xref: RelationshipXref intact EBI-7522465 identity
evidence: Evidence 3511f77c-20c5-4e83-99d6-2e88225a9bb3 IM-15332-10435 431625 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 2.04692146900628
comment: author-confidence:reliability score: 0.983
comment: comment:mint
data source: intact
participant: rpa49_yeast
participant: rpa1_yeast

ExperimentalForm a16f74d5-5292-4a43-ba67-1a79838f3b90
type: ExperimentalForm
experimental feature: ModificationFeature 3c309c42-4aca-4779-a433-4cf9a649d042 430727
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7519023 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7519023
db: intact

RelationshipXref dip DIP-2250N
type: RelationshipXref
id: DIP-2250N
db: database of interacting proteins

rpn9_yeast
type: Protein
evidence: Evidence ff4c6e01-e577-4631-add7-99e8ddbda7bd p 433668
entity reference: Q04062
name: 26S proteasome regulatory subunit RPN9
comment: psi-mi participant
data source: intact

rfc5_yeast
type: Protein
evidence: Evidence 2177fe40-5e57-4e75-9be8-34c1d0a27bb3 p 430906
entity reference: P38251
name: Replication factor C subunit 5
comment: psi-mi participant
data source: intact

ExperimentalForm 93b1979f-44bd-454b-875e-ac34e03001f4
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7532129 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7532129
db: intact

RelationshipXref intact EBI-7526601 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7526601
db: intact

UnificationXref molecular interactions ontology MI 0360
type: UnificationXref
id: MI:0360
db: molecular interactions ontology

UnificationXref uniprot knowledgebase Q12347
type: UnificationXref
id: Q12347
db: uniprot knowledgebase

RelationshipXref imex IM-15332-5992 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5992
db: imex

RelationshipXref intact EBI-7531844 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7531844
db: intact

RelationshipXref interpro IPR019734
type: RelationshipXref
id: IPR019734
db: interpro

ExperimentalForm 4ebc995f-249c-4708-b72f-e806698c2d03
type: ExperimentalForm
experimental feature: ModificationFeature 6240e2d8-a90a-414f-b5d9-688bda28bbff 432788
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

Evidence 8518c233-5db3-476c-bc03-349ee84c04b2 IM-15332-1225 433725 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref molecular interactions ontology MI 0359
type: UnificationXref
id: MI:0359
db: molecular interactions ontology

UnificationXref molecular interactions ontology MI 0355
type: UnificationXref
id: MI:0355
db: molecular interactions ontology

UnificationXref molecular interactions ontology MI 0354
type: UnificationXref
id: MI:0354
db: molecular interactions ontology

ExperimentalForm bb51b866-1e43-4d1e-bf5c-15258267c1a0
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

Evidence 1ee057e1-173c-42da-8d2a-79e1aa4297f2 IM-15332-8407 430781 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref intact EBI-7524975 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7524975
db: intact

RelationshipXref imex IM-15332-7635 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-7635
db: imex

Evidence 356054ae-aa48-42a3-b898-7472c369769e IM-15332-4769 431345 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref intact EBI-7522449 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7522449
db: intact

ExperimentalForm 3e7733c8-1355-405b-ac0c-d8ae4e6b0c4b
type: ExperimentalForm
experimental feature: ModificationFeature bf1ba552-d5bd-4a21-a3df-e91fb7616d46 432688
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-9211 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-9211
db: imex

rpab1_yeast
type: Protein
evidence: Evidence e8a743f7-c108-47c8-ba45-e8d2fcf15233 p 430494
entity reference: rpab1_yeast
name: DNA-directed RNA polymerases I, II, and III subunit RPABC1
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-4860 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-4860
db: intact

RelationshipXref interpro IPR002164
type: RelationshipXref
id: IPR002164
db: interpro

UnificationXref uniprot knowledgebase Q12321
type: UnificationXref
id: Q12321
db: uniprot knowledgebase

ExperimentalForm 1f38fe33-dc7c-483c-ac8e-1c8bc46d78c5
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref refseq NP 015104 1
type: RelationshipXref
id: NP_015104.1
db: refseq

ExperimentalForm f0f2715f-07a2-413f-b8f1-991144fbef9b
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref go GO 0005198
type: RelationshipXref
id: GO:0005198
db: gene ontology

RelationshipXref uniprotkb D6VWG6 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VWG6
db: uniprot knowledgebase

ret2-sec27-1
type: MolecularInteraction
xref: RelationshipXref intact EBI-7516070 identity
xref: RelationshipXref imex IM-15332-799 imex-primary
xref: UnificationXref mint MINT-2196168
evidence: Evidence 60abf3f4-7f75-4d77-83bb-d1a093035ffe IM-15332-799 430593 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 6.68546277167419
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P43621 identity 1529029541700
participant: Protein uniprotkb P41811 identity 1529029541701

dna2_yeast
type: Protein
evidence: Evidence d1e8c7e4-4321-4de6-81f8-d266f649b029 p 430872
entity reference: P38859
name: DNA replication ATP-dependent helicase/nuclease DNA2
comment: psi-mi participant
data source: intact

ExperimentalForm a14e5d15-640a-4c06-aa57-08017b0d94ae
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7536233 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7536233
db: intact

RelationshipXref rcsb pdb 1S1I
type: RelationshipXref
id: 1S1I
db: protein data bank

RelationshipXref intact EBI-7532436 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7532436
db: intact

ExperimentalForm c6bfa9c5-04ff-4e7c-8331-0c003e150ea3
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rfa3_yeast
type: Protein
evidence: Evidence c6bdf35c-0baf-476b-905b-406cbbc6e68c p 430700
entity reference: P26755
name: Replication factor A protein 3
comment: psi-mi participant
data source: intact

ExperimentalForm 9c3a16fc-435c-46ba-9885-6ef00305425c
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref refseq NP 014045 1
type: RelationshipXref
id: NP_014045.1
db: refseq

RelationshipXref imex IM-15332-8823 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-8823
db: imex

ExperimentalForm 7858f15b-4e95-433a-a927-bdee932a32c0
type: ExperimentalForm
experimental feature: ModificationFeature 4a556afa-28e4-4cd5-abb4-c9fff694694d 432348
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

UnificationXref mint MINT-2207996
type: UnificationXref
id: MINT-2207996
db: mint

RelationshipXref interpro IPR002143
type: RelationshipXref
id: IPR002143
db: interpro

RelationshipXref sgd S000000215
type: RelationshipXref
id: S000000215
db: sgd

RelationshipXref rcsb pdb 3PO3
type: RelationshipXref
id: 3PO3
db: protein data bank

RelationshipXref rcsb pdb 3PO2
type: RelationshipXref
id: 3PO2
db: protein data bank

RelationshipXref uniprotkb Q99187 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: Q99187
db: uniprot knowledgebase

pra1_yeast
type: ProteinReference
sequence: MNQLGALAQVSRFTQNFSMENIKSEFQSLQSKLATLRTPQEFFNFKKISKPQNFGEVQSRVAYNLKYFSSNYGLIIGCLSIYTLLTNLLLLFVIVLVVAGIVGINKLKGEELVTPFGSFKTNQLYTGLVCVAVPIGFLASPISTLLWLIGASAVSVFGHASLMEKPIETVFDEETV
xref: RelationshipXref intact EBI-25301 identity
xref: RelationshipXref sgd S000004989
xref: UnificationXref uniprot knowledgebase P53633
xref: RelationshipXref dip DIP-2059N
xref: RelationshipXref go GO 0000139
xref: RelationshipXref go GO 0016021
xref: RelationshipXref uniprotkb D6W1D5 secondary-ac
xref: RelationshipXref go GO 0005783
xref: RelationshipXref go GO 0030134
xref: RelationshipXref mint P53633
xref: RelationshipXref interpro IPR004895
xref: RelationshipXref go GO 0005794
xref: RelationshipXref refseq NP 014354 2
xref: RelationshipXref go GO 0006888
organism: http://identifiers.org/taxonomy/559292
name: PRA1
name: YNL044W
name: YIP3
name: Prenylated Rab acceptor 1
name: N2650

UnificationXref mint MINT-2211092
type: UnificationXref
id: MINT-2211092
db: mint

ExperimentalForm a817c7c3-435f-4d3a-81d1-72f4aaa938a9
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm fc67023a-9a89-4ba8-b815-5fcbfa02fb28
type: ExperimentalForm
experimental feature: ModificationFeature 28acb6c3-cf30-4575-a7f3-42fc119e8b2b 432679
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

Evidence abd39eb4-67f4-4969-a20f-05025ed22fe5 IM-15332-1600 433913 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ret2-sec27-7
type: MolecularInteraction
xref: UnificationXref mint MINT-2196402
xref: RelationshipXref imex IM-15332-1206 imex-primary
xref: RelationshipXref intact EBI-7516440 identity
evidence: Evidence d13f5bcc-c90b-41c9-9847-a430d0cef14a IM-15332-1206 430645 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 0.0651173699051292
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P43621 identity 1529029541726
participant: Protein uniprotkb P41811 identity 1529029541727

RelationshipXref go GO 0035861
type: RelationshipXref
id: GO:0035861
db: gene ontology

RelationshipXref intact EBI-7531796 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7531796
db: intact

RelationshipXref imex IM-15332-1580 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1580
db: imex

RelationshipXref go GO 0006511
type: RelationshipXref
id: GO:0006511
db: gene ontology

Evidence b9af2d57-04fc-4776-b565-4f917af04116 IM-15332-795 430349 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm b5125001-b2e8-4c45-9f2d-48d39aed96fd
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref refseq NP 012508 1
type: RelationshipXref
id: NP_012508.1
db: refseq

UnificationXref mint MINT-2200202
type: UnificationXref
id: MINT-2200202
db: mint

RelationshipXref reactome REACT 343353
type: RelationshipXref
id: REACT_343353
db: reactome

UnificationXref mint MINT-2207978
type: UnificationXref
id: MINT-2207978
db: mint

rpb9-rpb2-5
type: MolecularInteraction
xref: RelationshipXref intact EBI-7530914 identity
xref: UnificationXref mint MINT-2204654
xref: RelationshipXref imex IM-15332-7640 imex-primary
evidence: Evidence fb3a4f03-2e9d-4330-9cc6-6097fad6ace3 IM-15332-7640 432473 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.989
comment: author-confidence:z-score: 1.55472945105704
comment: comment:mint
data source: intact
participant: Protein uniprotkb P27999 identity 1529029542640
participant: Protein uniprotkb P08518 identity 1529029542641

RelationshipXref go GO 0006508
type: RelationshipXref
id: GO:0006508
db: gene ontology

ExperimentalForm 58944345-658e-4b72-8bc7-0b29b25f5ded
type: ExperimentalForm
experimental feature: ModificationFeature f9f577e7-e805-4f6a-8b40-70cba1dd72f5 430408
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-10667 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-10667
db: intact

RelationshipXref rcsb pdb 3PLT
type: RelationshipXref
id: 3PLT
db: protein data bank

RelationshipXref uniprotkb D6VT36 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VT36
db: uniprot knowledgebase

RelationshipXref uniprotkb D6W0N3 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6W0N3
db: uniprot knowledgebase

ExperimentalForm 5d2af46c-81b7-45c1-bd76-6b7979d5eb76
type: ExperimentalForm
experimental feature: ModificationFeature ea8bfb50-76be-4916-a076-c63744a04480 432332
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

UnificationXref mint MINT-2211074
type: UnificationXref
id: MINT-2211074
db: mint

rpg1-tif34-1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-12891 imex-primary
xref: UnificationXref mint MINT-2209364
xref: RelationshipXref intact EBI-7539770 identity
evidence: Evidence 60ada8b5-8e15-4992-8067-64d179cc8ca2 IM-15332-12891 433513 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 0.0831558517166425
comment: comment:mint
comment: author-confidence:reliability score: 0.972
data source: intact
participant: Protein uniprotkb P40217 identity 1529029543160
participant: Protein uniprotkb P38249 identity 1529029543161

RelationshipXref intact EBI-7521149 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7521149
db: intact

Evidence d6e9b19d-003b-4b17-8d40-69ca925c3874 IM-15332-8821 433221 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpb11-dst1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-9610 imex-primary
xref: UnificationXref mint MINT-2203227
xref: RelationshipXref intact EBI-7526402 identity
evidence: Evidence a698054c-a39e-4c48-975b-0e6c4e4880b2 IM-15332-9610 432161 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 9.24545665577136
comment: author-confidence:reliability score: 0.987
comment: comment:mint
data source: intact
participant: Protein uniprotkb P07273 identity 1529029542485
participant: Protein uniprotkb P38902 identity 1529029542484

Evidence 50d1493d-d4a4-45f0-a85d-8d4c975f6564 IM-15332-8822 433369 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

Evidence b1b42b75-7829-4d96-9d45-7def4d25f671 IM-15332-1212 431337 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref imex IM-15332-9627 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-9627
db: imex

UnificationXref mint MINT-2207960
type: UnificationXref
id: MINT-2207960
db: mint

RelationshipXref interpro IPR002110
type: RelationshipXref
id: IPR002110
db: interpro

RelationshipXref go GO 0034497
type: RelationshipXref
id: GO:0034497
db: gene ontology

ExperimentalForm 08a20bcf-9b6a-4283-a43c-a8016920ce37
type: ExperimentalForm
experimental feature: ModificationFeature 0da44742-1f51-48ee-a423-5acf59cb27cc 431900
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref refseq NP 013293 1
type: RelationshipXref
id: NP_013293.1
db: refseq

RelationshipXref imex IM-15332-1586 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1586
db: imex

RelationshipXref dip DIP-1528N
type: RelationshipXref
id: DIP-1528N
db: database of interacting proteins

RelationshipXref intact EBI-7522914 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7522914
db: intact

RelationshipXref interpro IPR002109
type: RelationshipXref
id: IPR002109
db: interpro

ExperimentalForm d8a41fbc-0ab3-4002-b35c-7347377e95e4
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7520274 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7520274
db: intact

ExperimentalForm 159124f7-2074-4740-a48a-26ca0a13b3fb
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm a4cb1226-80ca-4468-b49b-942e4a2ceb30
type: ExperimentalForm
experimental feature: ModificationFeature 5ea7e56f-d098-40cb-aa64-0fadac0d55b0 432396
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rim4-crn1
type: MolecularInteraction
xref: RelationshipXref intact EBI-7518891 identity
xref: UnificationXref mint MINT-2198510
xref: RelationshipXref imex IM-15332-388 imex-primary
evidence: Evidence 8f32a5fd-d1c4-4bdc-91ee-4459c489de57 IM-15332-388 431113 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.617
comment: author-confidence:z-score: 1.90237616240052
comment: comment:mint
data source: intact
participant: rim4_yeast
participant: Protein uniprotkb Q06440 identity 1529029541961

UnificationXref mint MINT-2211056
type: UnificationXref
id: MINT-2211056
db: mint

RelationshipXref rcsb pdb 1HUK
type: RelationshipXref
id: 1HUK
db: protein data bank

RelationshipXref rcsb pdb 1HUJ
type: RelationshipXref
id: 1HUJ
db: protein data bank

RelationshipXref intact EBI-7523603 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7523603
db: intact

rpb10-rpb7
type: MolecularInteraction
xref: UnificationXref mint MINT-2202165
xref: RelationshipXref imex IM-15332-8024 imex-primary
xref: RelationshipXref intact EBI-7524352 identity
evidence: Evidence fc5bdac9-9dd8-4c94-886a-fea64bd267de IM-15332-8024 431925 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.989
comment: author-confidence:z-score: 6.46930496046582
comment: comment:mint
data source: intact
participant: Protein uniprotkb P22139 identity 1529029542366
participant: rpb7_yeast

UnificationXref mint MINT-2207942
type: UnificationXref
id: MINT-2207942
db: mint

has1_yeast
type: Protein
evidence: Evidence cc54cd55-f3e7-47ec-9147-22af18953678 p 433590
entity reference: Q03532
name: ATP-dependent RNA helicase HAS1
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7534368 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7534368
db: intact

RelationshipXref intact EBI-7532159 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7532159
db: intact

RelationshipXref rcsb pdb 2LO6
type: RelationshipXref
id: 2LO6
db: protein data bank

UnificationXref mint MINT-2206592
type: UnificationXref
id: MINT-2206592
db: mint

RelationshipXref reactome R-SCE-674695
type: RelationshipXref
id: R-SCE-674695
db: reactome

Evidence f26d9e99-e361-4cb9-9bb9-dc8153713ff6 IM-15332-6386 433197 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

pkh1_yeast
type: Protein
evidence: Evidence d3cb4250-e368-4d55-8ee5-704fb8a23bbe p 430432
entity reference: Q03407
name: Serine/threonine-protein kinase PKH1
comment: psi-mi participant
data source: intact

ExperimentalForm a3061458-541e-47b6-984d-d20820aca718
type: ExperimentalForm
experimental feature: ModificationFeature 3aca9d11-7574-4580-bb28-31dd02beda2c 431507
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7522517 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7522517
db: intact

eaf3_yeast
type: Protein
evidence: Evidence 78ccd800-8e8f-480b-9010-02f819d1e8f9 p 430390
entity reference: Q12432
name: Chromatin modification-related protein EAF3
comment: psi-mi participant
data source: intact

ExperimentalForm 0aecb7d9-728f-488a-98bc-da3f1c475f43
type: ExperimentalForm
experimental feature: ModificationFeature d913fc97-55e5-4c82-b4d1-6de70da64ba5 430464
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref mint P36121
type: RelationshipXref
id: P36121
db: mint

eaf3_yeast
type: Protein
evidence: Evidence 7ac8a736-13f9-4b3c-8ed3-0610c7fc8a12 p 430384
entity reference: Q12432
name: Chromatin modification-related protein EAF3
comment: psi-mi participant
data source: intact

rpc19-rpa135-1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-10446 imex-primary
xref: UnificationXref mint MINT-2205727
xref: RelationshipXref intact EBI-7532467 identity
evidence: Evidence 69ae9639-f631-4699-a4c6-9f27c43b8b87 IM-15332-10446 432705 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 1.91096424395105
comment: author-confidence:reliability score: 0.875
comment: comment:mint
data source: intact
participant: Protein uniprotkb P22138 identity 1529029542756
participant: Protein uniprotkb P28000 identity 1529029542757

eaf3_yeast
type: Protein
evidence: Evidence 2959ed63-abb2-431b-8e40-7273dcb87369 p 430378
entity reference: Q12432
name: Chromatin modification-related protein EAF3
comment: psi-mi participant
data source: intact

eaf3_yeast
type: Protein
evidence: Evidence 5ba606f5-003a-4d9d-aab1-fe91b111e679 p 430376
entity reference: Q12432
name: Chromatin modification-related protein EAF3
comment: psi-mi participant
data source: intact

RelationshipXref refseq NP 009653 2
type: RelationshipXref
id: NP_009653.2
db: refseq

ExperimentalForm 2af7cdd0-4378-479d-a74b-41ea3f9172e2
type: ExperimentalForm
experimental feature: ModificationFeature 9963b719-cc69-4b08-a034-a05cab07396f 431359
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpc6_yeast
type: Protein
evidence: Evidence 3e43b9f5-5997-4157-965d-1c940d0b3e36 p 432983
entity reference: P32910
name: DNA-directed RNA polymerase III subunit RPC6
comment: psi-mi participant
data source: intact

rfc1-rfc2-10
type: MolecularInteraction
xref: RelationshipXref intact EBI-7517740 identity
xref: RelationshipXref imex IM-15332-5582 imex-primary
xref: UnificationXref mint MINT-2197628
evidence: Evidence 762107a0-92d9-4511-990a-84afd67db611 IM-15332-5582 430917 430156
interaction type: physical association
comment: author-confidence:z-score: 3.86603563929556
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.787
data source: intact
participant: Protein uniprotkb P40348 identity 1529029541863
participant: Protein uniprotkb P38630 identity 1529029541862

rpc6_yeast
type: Protein
evidence: Evidence c1faba7c-4e38-4552-8224-726042d4e1c7 p 432978
entity reference: P32910
name: DNA-directed RNA polymerase III subunit RPC6
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-12062 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12062
db: imex

UnificationXref mint MINT-2198798
type: UnificationXref
id: MINT-2198798
db: mint

UnificationXref uniprot knowledgebase Q06440
type: UnificationXref
id: Q06440
db: uniprot knowledgebase

ExperimentalForm 52ecfc0f-4594-4f79-b04f-0dd62c875324
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

eaf3_yeast
type: Protein
evidence: Evidence 7ad61f70-216d-4295-abbb-b98de0915981 p 430370
entity reference: Q12432
name: Chromatin modification-related protein EAF3
comment: psi-mi participant
data source: intact

eaf3_yeast
type: Protein
evidence: Evidence 6fa77237-b6e7-4915-a8ed-d02d7e1d2cda p 430366
entity reference: Q12432
name: Chromatin modification-related protein EAF3
comment: psi-mi participant
data source: intact

RelationshipXref go GO 0000131
type: RelationshipXref
id: GO:0000131
db: gene ontology

rpb11-rpb2-3
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-396 imex-primary
xref: UnificationXref mint MINT-2203515
xref: RelationshipXref intact EBI-7526921 identity
evidence: Evidence ef8d7ba5-9d9b-408f-b444-734aecaa0954 IM-15332-396 432225 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.988
comment: comment:mint
comment: author-confidence:z-score: 1.33798309221979
data source: intact
participant: Protein uniprotkb P08518 identity 1529029542517
participant: Protein uniprotkb P38902 identity 1529029542516

RelationshipXref interpro IPR000358
type: RelationshipXref
id: IPR000358
db: interpro

rpc6_yeast
type: Protein
evidence: Evidence b5d2663a-29bd-4ce4-a0e0-8c0042f7490c p 432967
entity reference: P32910
name: DNA-directed RNA polymerase III subunit RPC6
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2201606
type: UnificationXref
id: MINT-2201606
db: mint

rpc6_yeast
type: Protein
evidence: Evidence fcb5bb06-e1be-4fea-95df-612dda77f104 p 432962
entity reference: P32910
name: DNA-directed RNA polymerase III subunit RPC6
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2206574
type: UnificationXref
id: MINT-2206574
db: mint

UnificationXref mint MINT-2211020
type: UnificationXref
id: MINT-2211020
db: mint

rpc6_yeast
type: Protein
evidence: Evidence 00ca50d6-f55c-431f-ae28-0067f61a504d p 432954
entity reference: P32910
name: DNA-directed RNA polymerase III subunit RPC6
comment: psi-mi participant
data source: intact

RelationshipXref dip DIP-1524N
type: RelationshipXref
id: DIP-1524N
db: database of interacting proteins

rpc8_yeast
type: Protein
evidence: Evidence cd32d959-be59-4506-b88a-d5071d70d94a p 432904
entity reference: P35718
name: DNA-directed RNA polymerase III subunit RPC8
comment: psi-mi participant
data source: intact

RelationshipXref mint P36104
type: RelationshipXref
id: P36104
db: mint

RelationshipXref imex IM-15332-6368 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-6368
db: imex

ExperimentalForm 06774bcb-0546-4a6d-9cfc-a6f67ab5d4ea
type: ExperimentalForm
experimental feature: ModificationFeature 33d8b412-92f2-436e-9316-da45bed93631 430448
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

UnificationXref mint MINT-2195898
type: UnificationXref
id: MINT-2195898
db: mint

RelationshipXref dip DIP-337N
type: RelationshipXref
id: DIP-337N
db: database of interacting proteins

RelationshipXref intact EBI-29234 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-29234
db: intact

rpc6_yeast
type: Protein
evidence: Evidence 50813ee1-e57c-4eaf-820f-1f8c95315fa8 p 432951
entity reference: P32910
name: DNA-directed RNA polymerase III subunit RPC6
comment: psi-mi participant
data source: intact

rpc6_yeast
type: Protein
evidence: Evidence b5ccd911-e8bc-4c8c-ab28-918c62efdfbd p 432946
entity reference: P32910
name: DNA-directed RNA polymerase III subunit RPC6
comment: psi-mi participant
data source: intact

rpc6_yeast
type: Protein
evidence: Evidence 1945a1c7-54f5-4265-9b06-1c84ba13886f p 432943
entity reference: P32910
name: DNA-directed RNA polymerase III subunit RPC6
comment: psi-mi participant
data source: intact

rpc6_yeast
type: Protein
evidence: Evidence 950ea642-2050-4cf6-9fe6-b90bbccd47ae p 432934
entity reference: P32910
name: DNA-directed RNA polymerase III subunit RPC6
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2200274
type: UnificationXref
id: MINT-2200274
db: mint

ExperimentalForm 6e306277-e35d-4461-bce2-40ecedd20a7a
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7523248 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7523248
db: intact

RelationshipXref rcsb pdb 4QVM
type: RelationshipXref
id: 4QVM
db: protein data bank

UnificationXref mint MINT-2207906
type: UnificationXref
id: MINT-2207906
db: mint

rgp1-mck1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-4765 imex-primary
xref: RelationshipXref intact EBI-7518124 identity
xref: UnificationXref mint MINT-2197844
evidence: Evidence cc9e18ed-4051-44ab-bffe-fa4d0f1bc3a9 IM-15332-4765 430965 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.752
comment: author-confidence:z-score: 6.82252986398456
comment: comment:mint
data source: intact
participant: mck1_yeast
participant: Protein uniprotkb P16664 identity 1529029541887

RelationshipXref intact EBI-7534544 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7534544
db: intact

atg11_yeast
type: ProteinReference
sequence: MADADEYSTAPTQQEITPLQTTATIINAISGECITTNVDFFVSLDKFKQFIARKWKIPPDQLLILLPYGNKLKPSMFKELLINRSFTLNDFYVYDRRLFSLVSKPTPTNLLTSKDSNPMNSPNSNDLTETLEYLIKNSHISQYQGSDTIMIKPMPSPLEDADVDLSRLNYHSVTSLLTTNLGWLSALEIDVHYFKSLIPDIIAHIKRIFDGLTVCSQYLKLYCFDVESLYNSNVQFLNQLVDNGMTSKWEKCFNDTLSKLTALEGDSLQKFINIESLLENEKSVKILNHSINGKLNKIKREIDENASFRDIITVNIDRLRQMFTPNESKFELEDQMAESFEVLVSEMRTRSRNVLDKEEEEFNSQEFLKSMNVMLEKDKKESVKTLFTISQALYSQIGELIDLKKSLQKHAVAILGNIAFTQMEILGIKRLLLNECNKDLELYKKYEVEFAQVEDLPLIYGLYLIEKYRRLSWFQQILSFISNFNQDLELFKQNELRTRNKWVKNFGSIATVFCEDLLSSSDFKRLNEYHSHTSPPNEDEEDENENSIANYRQDLVKVSQAIDNYMTQIKETDVSEPIIDLLSKTLFETKRFHIIYSNFKNNNNNSSNGNSISPEGSIALKSDDVVKGYKTRIKKLESLLHEFQYSDIGHWPQGVLNTHLKPFRGSATSINKKKFLGASVLLEPANISEVNIDSVSQANNHQIQELESNVDDLLHQLQLLKEENNRKSMQISEMGKKISDLEVEKTAYRETLTNLNQELARLTNEEQSHRTEIFTLNASFKKQLNDIISQDNEKIEKLTGDYDDVSKSRERLQMDLDESNKKHEQEVNLLKADIERLGKQIVTSEKSYAETNSSSMEKGEKFETIPLAEDPGRENQISAYTQTLQDRIFDIISTNIFILENIGLLLTFDNNNNIQIRRVKGLKKGTAQSNILDESTQMLDAHDNSLIKSPVFQKLKDEYELIKSVANGSEKDTQQSIFLGNITQLYDNKLYEVAVIRRFKDIETLAKKLTKENKIKRTLLERFQREKVTLRNFQIGDLALFLPTRENVNSVGSMSSSTSSLSSSFSSVDLSTPPPLDAMSIQSSPSVIHSNVINQASISGRDKNKLMRPWAAFTAFEESTRYFLKDEKGLTKGKEWFVGRIVTLEHFVADSPSNNPFRLPKGSVWFQVTAVVVSYQGV
xref: RelationshipXref uniprotkb D6W457 secondary-ac
xref: RelationshipXref go GO 1990316
xref: RelationshipXref go GO 0034045
xref: RelationshipXref go GO 0000407
xref: RelationshipXref go GO 0030242
xref: RelationshipXref go GO 0034497
xref: RelationshipXref go GO 0001934
xref: UnificationXref uniprot knowledgebase Q12527
xref: RelationshipXref go GO 0015031
xref: RelationshipXref dip DIP-1492N
xref: RelationshipXref sgd S000006253
xref: RelationshipXref go GO 0000045
xref: RelationshipXref interpro IPR019460
xref: RelationshipXref go GO 0000422
xref: RelationshipXref go GO 0000149
xref: RelationshipXref go GO 0032947
xref: RelationshipXref go GO 2000786
xref: RelationshipXref go GO 0005774
xref: RelationshipXref go GO 0032258
xref: RelationshipXref go GO 0019898
xref: RelationshipXref go GO 0061723
xref: RelationshipXref go GO 0061709
xref: RelationshipXref refseq NP 015374 1
xref: RelationshipXref go GO 0019901
xref: RelationshipXref mint Q12527
xref: RelationshipXref go GO 0034727
xref: RelationshipXref intact EBI-31977 identity
organism: http://identifiers.org/taxonomy/559292
name: Autophagy-related protein 11
name: Cytoplasm to vacuole targeting protein 9
name: CVT9
name: YPR049C
name: ATG11
name: YP9499.07c

RelationshipXref rcsb pdb 5WYK
type: RelationshipXref
id: 5WYK
db: protein data bank

RelationshipXref rcsb pdb 5WYJ
type: RelationshipXref
id: 5WYJ
db: protein data bank

tho2-hrb1-6
type: MolecularInteraction
xref: RelationshipXref intact EBI-7520174 identity
xref: UnificationXref mint MINT-2199302
xref: RelationshipXref imex IM-15332-7628 imex-primary
evidence: Evidence 1138fa1f-ae0d-40ef-a3b7-35016bdef0d6 IM-15332-7628 431289 430156
interaction type: physical association
comment: comment:mint
comment: author-confidence:reliability score: 0.762
comment: author-confidence:z-score: 0.17292858488599
data source: intact
participant: Protein uniprotkb P53552 identity 1529029542048
participant: Protein uniprotkb P38922 identity 1529029542049

RelationshipXref intact EBI-7542984 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7542984
db: intact

UnificationXref mint MINT-2201624
type: UnificationXref
id: MINT-2201624
db: mint

ExperimentalForm e16ba05a-0ec6-49b5-a3f0-2a52f9929e54
type: ExperimentalForm
experimental feature: ModificationFeature 3985b1aa-547a-4057-af17-f612d4c3f60c 430459
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

UnificationXref mint MINT-2211002
type: UnificationXref
id: MINT-2211002
db: mint

rpc6_yeast
type: Protein
evidence: Evidence 337c39f5-4d16-433a-a7a4-a87498a89f25 p 432918
entity reference: P32910
name: DNA-directed RNA polymerase III subunit RPC6
comment: psi-mi participant
data source: intact

Evidence aab21d6b-6da3-440c-bbb7-f44b2ecbdd76 IM-15332-5168 430701 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

psa6_yeast
type: Protein
evidence: Evidence c8e2c08b-6e70-489d-a351-53ab450e1a5d p 432124
entity reference: P40302
name: Proteasome subunit alpha type-6
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-3998 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-3998
db: imex

rpb10-ret1
type: MolecularInteraction
xref: UnificationXref mint MINT-2203029
xref: RelationshipXref imex IM-15332-7203 imex-primary
xref: RelationshipXref intact EBI-7525783 identity
evidence: Evidence 84422c2e-62fb-4691-b795-474e37280a98 IM-15332-7203 432117 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:z-score: 2.80507032790092
comment: author-confidence:reliability score: 0.968
data source: intact
participant: Protein uniprotkb P22276 identity 1529029542462
participant: rpab5_yeast

rpa1_yeast
type: Protein
evidence: Evidence 85682d49-da73-4815-9748-e336ea4b04cf p 433184
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

prs4_yeast
type: Protein
evidence: Evidence a67509a3-9b33-4aff-97b7-05dcfac97e71 p 433892
entity reference: P40327
name: 26S proteasome regulatory subunit 4 homolog
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 2VUM
type: RelationshipXref
id: 2VUM
db: protein data bank

RelationshipXref sgd S000002545
type: RelationshipXref
id: S000002545
db: sgd

UnificationXref molecular interactions ontology MI 0496
type: UnificationXref
id: MI:0496
db: molecular interactions ontology

rpc6_yeast
type: Protein
evidence: Evidence 50a6ded0-c6d3-45e5-bc68-9a76a76975a2 p 432910
entity reference: P32910
name: DNA-directed RNA polymerase III subunit RPC6
comment: psi-mi participant
data source: intact

rpc6_yeast
type: Protein
evidence: Evidence 3c2275bf-5835-4c50-92bc-0e29b6beafca p 432908
entity reference: P32910
name: DNA-directed RNA polymerase III subunit RPC6
comment: psi-mi participant
data source: intact

prs4_yeast
type: Protein
evidence: Evidence 136d641f-9a60-4abf-b0bd-b36c5f0c2b2a p 433874
entity reference: P40327
name: 26S proteasome regulatory subunit 4 homolog
comment: psi-mi participant
data source: intact

rpc6_yeast
type: Protein
evidence: Evidence 94f6f0a9-379e-4bd0-a253-cd8ce158a5a0 p 432898
entity reference: P32910
name: DNA-directed RNA polymerase III subunit RPC6
comment: psi-mi participant
data source: intact

ExperimentalForm f7d247a8-f959-40bd-ae39-444dd17217ed
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7523009 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7523009
db: intact

RelationshipXref intact EBI-7532049 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7532049
db: intact

RelationshipXref rcsb pdb 5WWN
type: RelationshipXref
id: 5WWN
db: protein data bank

RelationshipXref refseq NP 014986 3
type: RelationshipXref
id: NP_014986.3
db: refseq

UnificationXref mint MINT-2195862
type: UnificationXref
id: MINT-2195862
db: mint

rco1-eaf3-5
type: MolecularInteraction
xref: UnificationXref mint MINT-2195249
xref: RelationshipXref intact EBI-7515103 identity
xref: RelationshipXref imex IM-15332-7187 imex-primary
evidence: Evidence fa378470-98c8-40ab-8b5f-9b06a98c1bb9 IM-15332-7187 430389 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.989
comment: comment:mint
comment: author-confidence:z-score: 9.38755959642849
data source: intact
participant: eaf3_yeast
participant: rco1_yeast

UnificationXref mint MINT-2201642
type: UnificationXref
id: MINT-2201642
db: mint

rpc17-rpo31-2
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-5592 imex-primary
xref: RelationshipXref intact EBI-7531874 identity
xref: UnificationXref mint MINT-2205385
evidence: Evidence 0a3467ee-19ca-4e50-9e94-8d009e8565c7 IM-15332-5592 432629 430156
interaction type: physical association
comment: author-confidence:z-score: 2.72166239415559
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: rpc9_yeast
participant: Protein uniprotkb P04051 identity 1529029542719

UnificationXref mint MINT-2206537
type: UnificationXref
id: MINT-2206537
db: mint

ExperimentalForm 989fef0e-1cde-41a6-8669-14371f158ff5
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

coq6_yeast
type: ProteinReference
sequence: MFFSKVMLTRRILVRGLATAKSSAPKLTDVLIVGGGPAGLTLAASIKNSPQLKDLKTTLVDMVDLKDKLSDFYNSPPDYFTNRIVSVTPRSIHFLENNAGATLMHDRIQSYDGLYVTDGCSKATLDLARDSMLCMIEIINIQASLYNRISQYDSKKDSIDIIDNTKVVNIKHSDPNDPLSWPLVTLSNGEVYKTRLLVGADGFNSPTRRFSQIPSRGWMYNAYGVVASMKLEYPPFKLRGWQRFLPTGPIAHLPMPENNATLVWSSSERLSRLLLSLPPESFTALINAAFVLEDADMNYYYRTLEDGSMDTDKLIEDIKFRTEEIYATLKDESDIDEIYPPRVVSIIDKTRARFPLKLTHADRYCTDRVALVGDAAHTTHPLAGQGLNMGQTDVHGLVYALEKAMERGLDIGSSLSLEPFWAERYPSNNVLLGMADKLFKLYHTNFPPVVALRTFGLNLTNKIGPVKNMIIDTLGGNEK
xref: RelationshipXref go GO 0005743
xref: RelationshipXref mint P53318
xref: RelationshipXref go GO 0006744
xref: RelationshipXref uniprotkb Q05675 secondary-ac
xref: RelationshipXref sgd S000003487
xref: RelationshipXref uniprotkb Q05674 secondary-ac
xref: RelationshipXref go GO 0016709
xref: RelationshipXref go GO 0008681
xref: UnificationXref uniprot knowledgebase P53318
xref: RelationshipXref interpro IPR036188
xref: RelationshipXref intact EBI-4943 identity
xref: RelationshipXref interpro IPR010971
xref: RelationshipXref interpro IPR000689
xref: RelationshipXref refseq NP 011771 1
xref: RelationshipXref go GO 0071949
xref: RelationshipXref go GO 0016712
xref: RelationshipXref uniprotkb D6VV35 secondary-ac
xref: RelationshipXref interpro IPR018168
xref: RelationshipXref interpro IPR002938
organism: http://identifiers.org/taxonomy/559292
name: COQ6
name: G9165
name: Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial
name: YGR255C

rpa1_yeast
type: Protein
evidence: Evidence 2d742f25-c48a-4598-a1c9-782dfc7b25bc p 433150
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

ret1-rpc53
type: MolecularInteraction
xref: UnificationXref mint MINT-2195790
xref: RelationshipXref intact EBI-7515645 identity
xref: RelationshipXref imex IM-15332-3976 imex-primary
evidence: Evidence e045292d-08a5-4b84-9b24-fed910676343 IM-15332-3976 430509 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.983
comment: author-confidence:z-score: 0.00340008036310616
comment: comment:mint
data source: intact
participant: Protein uniprotkb P22276 identity 1529029541658
participant: Protein uniprotkb P25441 identity 1529029541659

RelationshipXref interpro IPR010714
type: RelationshipXref
id: IPR010714
db: interpro

RelationshipXref rcsb pdb 5WVK
type: RelationshipXref
id: 5WVK
db: protein data bank

RelationshipXref rcsb pdb 5WVI
type: RelationshipXref
id: 5WVI
db: protein data bank

ExperimentalForm a894c754-aad5-4bfe-9045-90ca5047bebf
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref uniprotkb D6VVL8 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VVL8
db: uniprot knowledgebase

Evidence 3381c9a2-cdab-49f3-9795-8f8d93534ea5 IM-15332-5976 431025 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm 0774ea5f-8eb3-4a99-a3cb-9697c0c27c13
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref go GO 0034402
type: RelationshipXref
id: GO:0034402
db: gene ontology

Evidence a48a6cdc-815b-47f2-866e-20113ab1329f IM-15332-11247 431933 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpc8_yeast
type: Protein
evidence: Evidence f4ae85e6-758a-44b1-b872-6ff5cda4e1c4 p 432806
entity reference: P35718
name: DNA-directed RNA polymerase III subunit RPC8
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-4334 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-4334
db: intact

RelationshipXref rcsb pdb 3PAW
type: RelationshipXref
id: 3PAW
db: protein data bank

RelationshipXref rcsb pdb 5X6O
type: RelationshipXref
id: 5X6O
db: protein data bank

rpl1a-imd3
type: MolecularInteraction
xref: RelationshipXref intact EBI-7540704 identity
xref: RelationshipXref imex IM-15332-2761 imex-primary
xref: UnificationXref mint MINT-2209814
evidence: Evidence a1f03f8b-a3aa-4b57-88f5-cc40e42826ad IM-15332-2761 433613 430156
interaction type: physical association
comment: author-confidence:z-score: 5.57796938932812
comment: author-confidence:reliability score: 0.695
comment: comment:mint
data source: intact
participant: Protein uniprotkb P50095 identity 1529029543211
participant: Protein uniprotkb P53030 identity 1529029543210

ExperimentalForm 4de8c6d1-0b2a-41a9-a7db-247c322e9622
type: ExperimentalForm
experimental feature: ModificationFeature e39dc75d-8e03-4174-bb5f-d1d2869beee3 432408
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-1219 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1219
db: imex

ExperimentalForm 2ecf1a0c-f17f-4835-a69d-86643810b8a6
type: ExperimentalForm
experimental feature: ModificationFeature 5d370fd1-d8ce-4619-9d7c-73d5fcb2b8c7 431203
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

UnificationXref mint MINT-2206519
type: UnificationXref
id: MINT-2206519
db: mint

RelationshipXref interpro IPR017923
type: RelationshipXref
id: IPR017923
db: interpro

rpc40-rpa49-1
type: MolecularInteraction
xref: UnificationXref mint MINT-2207420
xref: RelationshipXref imex IM-15332-11259 imex-primary
xref: RelationshipXref intact EBI-7535752 identity
evidence: Evidence 47c45f58-1b62-4e3b-bda5-ca6397dd2552 IM-15332-11259 433081 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 6.76376426930351
comment: author-confidence:reliability score: 0.983
comment: comment:mint
data source: intact
participant: Protein uniprotkb Q01080 identity 1529029542945
participant: Protein uniprotkb P07703 identity 1529029542944

RelationshipXref interpro IPR017927
type: RelationshipXref
id: IPR017927
db: interpro

Evidence 960b3c39-7a73-49a6-ab68-056e4a1c313d IM-15332-5579 430597 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref intact EBI-7515190 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7515190
db: intact

tho2-tex1-1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-12871 imex-primary
xref: RelationshipXref intact EBI-7519203 identity
xref: UnificationXref mint MINT-2198798
evidence: Evidence 8151f366-a36e-4e69-bd6d-52797d4b6b70 IM-15332-12871 431177 430156
interaction type: physical association
comment: comment:mint
comment: author-confidence:z-score: 9.47197385048092
comment: author-confidence:reliability score: 0.943
data source: intact
participant: tex1_yeast
participant: tho2_yeast

RelationshipXref interpro IPR016588
type: RelationshipXref
id: IPR016588
db: interpro

RelationshipXref intact EBI-6314 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-6314
db: intact

UnificationXref mint MINT-2205169
type: UnificationXref
id: MINT-2205169
db: mint

RelationshipXref reactome R-SCE-1236978
type: RelationshipXref
id: R-SCE-1236978
db: reactome

ExperimentalForm eb9ac0b6-5450-4ad2-92c0-d97c81ac58c8
type: ExperimentalForm
experimental feature: ModificationFeature 5f69244c-b5ad-4d02-b34c-3035f5437ac2 432308
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

prs4_yeast
type: Protein
evidence: Evidence 8bcdb181-a972-48dc-b81e-43fcf0d9b643 p 433810
entity reference: P40327
name: 26S proteasome regulatory subunit 4 homolog
comment: psi-mi participant
data source: intact

Evidence 04c3811a-52ce-468e-beb7-55a4a75926df IM-15332-3163 431369 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref mint Q04067
type: RelationshipXref
id: Q04067
db: mint

RelationshipXref intact EBI-7520841 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7520841
db: intact

RelationshipXref intact EBI-7534882 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7534882
db: intact

UnificationXref mint MINT-2201678
type: UnificationXref
id: MINT-2201678
db: mint

UnificationXref mint MINT-2206501
type: UnificationXref
id: MINT-2206501
db: mint

RelationshipXref imex IM-15332-1965 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1965
db: imex

RelationshipXref interpro IPR004895
type: RelationshipXref
id: IPR004895
db: interpro

RelationshipXref intact EBI-7517170 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7517170
db: intact

ExperimentalForm 7cbc40bf-07bf-4c21-85e1-50eee9b7d23d
type: ExperimentalForm
experimental feature: ModificationFeature 901458fe-8e8a-4699-bd36-a6b7247371dd 431295
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

UnificationXref mint MINT-2195826
type: UnificationXref
id: MINT-2195826
db: mint

UnificationXref mint MINT-2205150
type: UnificationXref
id: MINT-2205150
db: mint

ExperimentalForm b4836f41-8a8d-4cc6-b204-c33d07ce8c30
type: ExperimentalForm
experimental feature: ModificationFeature 113eaa5b-6b5f-4538-9f65-6ea7595432c1 433331
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7521682 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7521682
db: intact

ExperimentalForm a09835ae-2832-4adc-91df-2c377e88dc79
type: ExperimentalForm
experimental feature: ModificationFeature 7ffa1487-a98d-43f3-88a1-4a7da8747ab7 433724
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpc7_yeast
type: Protein
evidence: Evidence 421a3642-bd4e-4587-ad10-0da7c82d2b24 p 433128
entity reference: P17890
name: DNA-directed RNA polymerase III subunit RPC7
comment: psi-mi participant
data source: intact

rpc6_yeast
type: Protein
evidence: Evidence cf9e2f4b-4388-4539-ad5c-1368f08b4a34 p 432796
entity reference: P32910
name: DNA-directed RNA polymerase III subunit RPC6
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-4943 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-4943
db: intact

RelationshipXref intact EBI-7522153 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7522153
db: intact

rir4_yeast
type: Protein
evidence: Evidence 6bf1bd4b-f93d-4a00-b8ce-4607f344193e p 431470
entity reference: rir4_yeast
name: Ribonucleoside-diphosphate reductase small chain 2
comment: psi-mi participant
data source: intact

rpa1_yeast
type: Protein
evidence: Evidence 7943c24e-e5e5-4b98-898e-35c5d25e9cc0 p 433072
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

rpa1_yeast
type: Protein
evidence: Evidence 1cc1a9b5-f936-4012-96c4-46a1c758acde p 433068
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-6668 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-6668
db: intact

ret2-sec26-7
type: MolecularInteraction
xref: RelationshipXref intact EBI-7516226 identity
xref: RelationshipXref imex IM-15332-12868 imex-primary
xref: UnificationXref mint MINT-2196312
evidence: Evidence 4e4b69be-5623-4820-abbc-7a027b251c04 IM-15332-12868 430625 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 0.944218517181007
comment: author-confidence:reliability score: 0.976
comment: comment:mint
data source: intact
participant: Protein uniprotkb P43621 identity 1529029541716
participant: Protein uniprotkb P41810 identity 1529029541717

UnificationXref mint MINT-2201696
type: UnificationXref
id: MINT-2201696
db: mint

Evidence daaacb38-bacd-4ab6-a418-0c513f1fa9be IM-15332-12061 433225 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

Evidence 761fda92-de9f-419e-a1df-0f5041d280cc IM-15332-3982 431881 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref mint MINT-2195808
type: UnificationXref
id: MINT-2195808
db: mint

UnificationXref mint MINT-2196006
type: UnificationXref
id: MINT-2196006
db: mint

UnificationXref mint MINT-2205132
type: UnificationXref
id: MINT-2205132
db: mint

rpc34-rpa135
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-5988 imex-primary
xref: UnificationXref mint MINT-2206718
xref: RelationshipXref intact EBI-7534450 identity
evidence: Evidence 9d62623d-e44a-4ec2-a423-8bde5f1f8fb3 IM-15332-5988 432925 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.688
comment: comment:mint
comment: author-confidence:z-score: 4.43191802001836
data source: intact
participant: Protein uniprotkb P32910 identity 1529029542866
participant: Protein uniprotkb P22138 identity 1529029542867

rpb9-tfg2-1
type: MolecularInteraction
xref: RelationshipXref intact EBI-7531304 identity
xref: RelationshipXref imex IM-15332-8025 imex-primary
xref: UnificationXref mint MINT-2204997
evidence: Evidence 195af11a-c5e8-4939-8360-cb942821c22c IM-15332-8025 432545 430156
interaction type: physical association
comment: author-confidence:z-score: 9.14709162205173
comment: comment:homomint
comment: author-confidence:reliability score: 0.989
comment: comment:mint
data source: intact
participant: Protein uniprotkb P27999 identity 1529029542676
participant: t2fb_yeast

Evidence ff25be03-9a32-43f9-b44d-8870c4308711 IM-15332-6381 432165 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

Evidence d3d366a0-6310-4fe7-ad11-f5ca3c58cfdb IM-15332-1590 432805 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref imex IM-15332-405 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-405
db: imex

Evidence 650a64ac-3722-40cd-b1c2-be62e6b45505 IM-15332-9622 433621 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref refseq NP 013703 1
type: RelationshipXref
id: NP_013703.1
db: refseq

Evidence fb3a4f03-2e9d-4330-9cc6-6097fad6ace3 IM-15332-7640 432473 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpb9-tfg1-6
type: MolecularInteraction
xref: RelationshipXref intact EBI-7531584 identity
xref: UnificationXref mint MINT-2205241
xref: RelationshipXref imex IM-15332-8816 imex-primary
evidence: Evidence 4263865c-e1f0-46fd-8877-d67475e085a4 IM-15332-8816 432597 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.887
comment: author-confidence:z-score: 0.255749593423199
comment: comment:mint
data source: intact
participant: Protein uniprotkb P41895 identity 1529029542703
participant: Protein uniprotkb P27999 identity 1529029542702

UnificationXref uniprot knowledgebase P02994
type: UnificationXref
id: P02994
db: uniprot knowledgebase

rpc40-atg11
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-2362 imex-primary
xref: UnificationXref mint MINT-2207996
xref: RelationshipXref intact EBI-7536478 identity
evidence: Evidence 054228d6-d0ec-4f9c-a4e3-73a8cb00a0a1 IM-15332-2362 433209 430156
interaction type: physical association
comment: author-confidence:z-score: 0.436417502597305
comment: author-confidence:reliability score: 0.425
comment: comment:mint
data source: intact
participant: Protein uniprotkb P07703 identity 1529029543009
participant: atg11_yeast

RelationshipXref imex IM-15332-1578 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1578
db: imex

RelationshipXref interpro IPR004859
type: RelationshipXref
id: IPR004859
db: interpro

ExperimentalForm 8893224f-e175-41fb-acb6-9ef5bd12862e
type: ExperimentalForm
experimental feature: ModificationFeature ce323021-a12e-4246-a17e-3912336bcfa5 430363
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7515516 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7515516
db: intact

rpn11_yeast
type: Protein
evidence: Evidence 7ec55215-3f30-4e4d-aa28-b2607ac8d3ff p 433706
entity reference: P43588
name: Ubiquitin carboxyl-terminal hydrolase RPN11
comment: psi-mi participant
data source: intact

UnificationXref uniprot knowledgebase P23643
type: UnificationXref
id: P23643
db: uniprot knowledgebase

ExperimentalForm 7ccc8811-2cce-4483-95dc-5b759a59edf3
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref mint MINT-2196024
type: UnificationXref
id: MINT-2196024
db: mint

rpab1_yeast
type: Protein
evidence: Evidence bb59f91a-939e-40f5-96b2-fdec6e39db12 p 433176
entity reference: rpab1_yeast
name: DNA-directed RNA polymerases I, II, and III subunit RPABC1
comment: psi-mi participant
data source: intact

ExperimentalForm 67ef20f2-46d9-47a4-a572-c468e844eda9
type: ExperimentalForm
experimental feature: ModificationFeature 8da4b3c5-b4cd-4e04-9ce3-7e56a4f0cb06 430859
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref sgd S000001575
type: RelationshipXref
id: S000001575
db: sgd

rpn1-rpt2-9
type: MolecularInteraction
xref: RelationshipXref intact EBI-7541451 identity
xref: RelationshipXref imex IM-15332-5601 imex-primary
xref: UnificationXref mint MINT-2210030
evidence: Evidence d3b3e6ac-8149-4a36-bc2d-652339d8aaee IM-15332-5601 433661 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.99
comment: author-confidence:z-score: 1.89477729789771
data source: intact
participant: prs4_yeast
participant: Protein uniprotkb P38764 identity 1529029543235

RelationshipXref mint P38888
type: RelationshipXref
id: P38888
db: mint

RelationshipXref imex IM-15332-8024 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-8024
db: imex

RelationshipXref mint P38886
type: RelationshipXref
id: P38886
db: mint

Evidence 6361a54a-5e4c-49bf-b04a-e37068af39a4 IM-15332-10044 433817 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref interpro IPR004843
type: RelationshipXref
id: IPR004843
db: interpro

RelationshipXref sgd S000002915
type: RelationshipXref
id: S000002915
db: sgd

rpab1_yeast
type: Protein
evidence: Evidence df2f1082-c6c3-4033-ab78-af6ef9c69453 p 433166
entity reference: rpab1_yeast
name: DNA-directed RNA polymerases I, II, and III subunit RPABC1
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7532563 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7532563
db: intact

rs24_yeast
type: ProteinReference
sequence: MSDAVTIRTRKVISNPLLARKQFVVDVLHPNRANVSKDELREKLAEVYKAEKDAVSVFGFRTQFGGGKSVGFGLVYNSVAEAKKFEPTYRLVRYGLAEKVEKASRQQRKQKKNRDKKIFGTGKRLAKKVARRNAD
xref: RelationshipXref interpro IPR012678
xref: RelationshipXref interpro IPR012677
xref: RelationshipXref rcsb pdb 3IZB
xref: RelationshipXref interpro IPR018098
xref: RelationshipXref go GO 0000462
xref: RelationshipXref go GO 0003735
xref: RelationshipXref refseq NP 010997 1
xref: RelationshipXref go GO 0022627
xref: RelationshipXref go GO 0006412
xref: RelationshipXref go GO 0005739
xref: RelationshipXref go GO 0000166
xref: RelationshipXref refseq NP 012195 1
xref: RelationshipXref sgd S000000876
xref: RelationshipXref intact EBI-16101 identity
xref: RelationshipXref sgd S000001331
xref: UnificationXref uniprot knowledgebase P26782
xref: RelationshipXref uniprotkb D3DLX9 secondary-ac
xref: RelationshipXref interpro IPR001976
organism: http://identifiers.org/taxonomy/559292
name: RPS24EB
name: RPS24EA
name: 40S ribosomal protein S24
name: YIL069C
name: RP50
name: RPS24B
name: RPS24A
name: YER074W

ExperimentalForm b13462da-8c00-4c77-9855-64a52a021ea8
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref uniprotkb D3DLS1 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D3DLS1
db: uniprot knowledgebase

RelationshipXref go GO 0006139
type: RelationshipXref
id: GO:0006139
db: gene ontology

ExperimentalForm c2eec33d-4926-4275-a6e3-1208e531fa1e
type: ExperimentalForm
experimental feature: ModificationFeature 1b451092-11ff-41f2-a023-99a1c81ec215 431236
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-1962 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1962
db: imex

RelationshipXref dip DIP-2380N
type: RelationshipXref
id: DIP-2380N
db: database of interacting proteins

ExperimentalForm 3f0e495e-a851-4cee-bf29-f69a235805b5
type: ExperimentalForm
experimental feature: ModificationFeature 26367c9c-dc8d-4ece-8a25-0d98347626bd 431656
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref sgd S000002903
type: RelationshipXref
id: S000002903
db: sgd

RelationshipXref intact EBI-18305 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-18305
db: intact

prs8_yeast
type: ProteinReference
sequence: MTAAVTSSNIVLETHESGIKPYFEQKIQETELKIRSKTENVRRLEAQRNALNDKVRFIKDELRLLQEPGSYVGEVIKIVSDKKVLVKVQPEGKYIVDVAKDINVKDLKASQRVCLRSDSYMLHKVLENKADPLVSLMMVEKVPDSTYDMVGGLTKQIKEIKEVIELPVKHPELFESLGIAQPKGVILYGPPGTGKTLLARAVAHHTDCKFIRVSGAELVQKYIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRVEGSGGGDSEVQRTMLELLNQLDGFETSKNIKIIMATNRLDILDPALLRPGRIDRKIEFPPPSVAARAEILRIHSRKMNLTRGINLRKVAEKMNGCSGADVKGVCTEAGMYALRERRIHVTQEDFELAVGKVMNKNQETAISVAKLFK
xref: RelationshipXref rcsb pdb 5MPC
xref: RelationshipXref rcsb pdb 5MPB
xref: RelationshipXref rcsb pdb 5MPA
xref: RelationshipXref go GO 0070651
xref: RelationshipXref rcsb pdb 3JCO
xref: RelationshipXref reactome R-SCE-349425
xref: RelationshipXref rcsb pdb 5MP9
xref: RelationshipXref reactome R-SCE-68949
xref: RelationshipXref go GO 0006338
xref: RelationshipXref sgd S000003016
xref: RelationshipXref interpro IPR035261
xref: RelationshipXref reactome R-SCE-69601
xref: RelationshipXref go GO 0006289
xref: RelationshipXref refseq NP 011467 1
xref: RelationshipXref uniprotkb D6VU92 secondary-ac
xref: RelationshipXref go GO 0043433
xref: RelationshipXref interpro IPR005937
xref: RelationshipXref interpro IPR003960
xref: RelationshipXref reactome R-SCE-69017
xref: RelationshipXref interpro IPR003593
xref: RelationshipXref rcsb pdb 5WVI
xref: RelationshipXref go GO 0045899
xref: RelationshipXref reactome R-SCE-8854050
xref: RelationshipXref go GO 0051091
xref: RelationshipXref reactome R-SCE-69229
xref: RelationshipXref go GO 0034515
xref: RelationshipXref interpro IPR003959
xref: RelationshipXref go GO 0005634
xref: RelationshipXref go GO 0031595
xref: RelationshipXref go GO 0043161
xref: RelationshipXref reactome R-SCE-1236978
xref: RelationshipXref interpro IPR027417
xref: RelationshipXref reactome R-SCE-5689880
xref: RelationshipXref go GO 0032968
xref: RelationshipXref reactome R-SCE-174113
xref: RelationshipXref go GO 0070682
xref: RelationshipXref reactome R-SCE-382556
xref: RelationshipXref intact EBI-13914 identity
xref: RelationshipXref go GO 0030433
xref: UnificationXref uniprot knowledgebase Q01939
xref: RelationshipXref dip DIP-979N
xref: RelationshipXref go GO 0019904
xref: RelationshipXref go GO 0005524
xref: RelationshipXref go GO 0017025
xref: RelationshipXref go GO 0008540
xref: RelationshipXref mint Q01939
xref: RelationshipXref reactome R-SCE-5668541
xref: RelationshipXref rcsb pdb 4CR4
xref: RelationshipXref rcsb pdb 4CR3
xref: RelationshipXref rcsb pdb 4CR2
xref: RelationshipXref reactome R-SCE-450408
xref: RelationshipXref rcsb pdb 5A5B
xref: RelationshipXref rcsb pdb 5WVK
xref: RelationshipXref reactome R-SCE-983168
xref: RelationshipXref go GO 0036402
xref: RelationshipXref reactome R-SCE-5687128
xref: RelationshipXref go GO 0016887
xref: RelationshipXref rcsb pdb 3JCP
organism: http://identifiers.org/taxonomy/559292
name: CRL3
name: YGL048C
name: TBY1
name: 26S proteasome regulatory subunit 8 homolog
name: TBPY
name: CIM3
name: SUG1
name: Protein CIM3
name: Protein SUG1
name: Tat-binding protein TBY1
name: RPT6

ExperimentalForm 9b797eac-8f5f-4567-8101-707caa4d18c7
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

reb1-top2
type: MolecularInteraction
xref: RelationshipXref intact EBI-7515284 identity
xref: RelationshipXref imex IM-15332-7620 imex-primary
xref: UnificationXref mint MINT-2195411
evidence: Evidence f1cc75b0-ad7b-4a8a-8333-355f934e6144 IM-15332-7620 430425 430156
interaction type: physical association
comment: author-confidence:z-score: 1.65206818218017
comment: author-confidence:reliability score: 0.855
comment: comment:mint
data source: intact
participant: Protein uniprotkb P21538 identity 1529029541617
participant: top2_yeast

ExperimentalForm 4936862b-c53d-479f-ad1a-dc67a8f860ac
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

Evidence 7ded27a6-7152-419a-a2d8-625ddb90c652 IM-15332-1570 430513 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref go GO 0071949
type: RelationshipXref
id: GO:0071949
db: gene ontology

ExperimentalForm c967239d-ff13-4ce0-abc0-3ec0aaa0a47d
type: ExperimentalForm
experimental feature: ModificationFeature efaca0e1-57bc-4865-aeae-586aec4da763 430807
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-4409 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-4409
db: imex

rpc9_yeast
type: Protein
evidence: Evidence f11d773c-d704-43b0-b0f3-390ca174d39b p 430508
entity reference: rpc9_yeast
name: DNA-directed RNA polymerase III subunit RPC9
comment: psi-mi participant
data source: intact

rpb10-rpo21-6
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-9206 imex-primary
xref: RelationshipXref intact EBI-7525498 identity
xref: UnificationXref mint MINT-2202813
evidence: Evidence 6667a237-e06d-4acb-a3da-0e0845eab6b3 IM-15332-9206 432069 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.968
comment: author-confidence:z-score: 2.71829659000824
data source: intact
participant: Protein uniprotkb P04050 identity 1529029542438
participant: rpab5_yeast

ExperimentalForm 88ddfd42-a73a-450d-b377-8a6e0848b015
type: ExperimentalForm
experimental feature: ModificationFeature 00331b9a-5b28-462c-9e0f-deab0d06bc78 430923
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref rcsb pdb 5WLC
type: RelationshipXref
id: 5WLC
db: protein data bank

RelationshipXref sgd S000001542
type: RelationshipXref
id: S000001542
db: sgd

ExperimentalForm 1847bdf0-9b8e-42ca-ad3b-ba45351e59b8
type: ExperimentalForm
experimental feature: ModificationFeature fbf8474c-0d60-499e-ba92-f6b98d78be3a 430612
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref dip DIP-2109N
type: RelationshipXref
id: DIP-2109N
db: database of interacting proteins

rpab1_yeast
type: Protein
evidence: Evidence d371779b-810e-4fd8-b1a3-67a0bf270bca p 433100
entity reference: rpab1_yeast
name: DNA-directed RNA polymerases I, II, and III subunit RPABC1
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-10452 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-10452
db: imex

ExperimentalForm f614ad1e-4acf-4d84-af77-9a9781d0e5ee
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7534950 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7534950
db: intact

ExperimentalForm be8ee186-bd39-40e4-af28-78fe8062b223
type: ExperimentalForm
experimental feature: ModificationFeature aa28f1bf-8118-447d-9950-7d5edbe644b4 430539
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-11256 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-11256
db: imex

ExperimentalForm 8fa06833-8030-4827-ada5-67f4e9eda279
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref mint MINT-2209274
type: UnificationXref
id: MINT-2209274
db: mint

dna2_yeast
type: Protein
evidence: Evidence 0e5e1a09-5f4f-473f-a0c0-c55cad44fae1 p 430792
entity reference: P38859
name: DNA replication ATP-dependent helicase/nuclease DNA2
comment: psi-mi participant
data source: intact

dna2_yeast
type: Protein
evidence: Evidence 1500975a-9c3f-427a-a8af-873f029a3e14 p 430788
entity reference: P38859
name: DNA replication ATP-dependent helicase/nuclease DNA2
comment: psi-mi participant
data source: intact

RelationshipXref go GO 0090297
type: RelationshipXref
id: GO:0090297
db: gene ontology

dna2_yeast
type: Protein
evidence: Evidence c6dfcbf9-ec3a-4cab-b766-93a899eee4e1 p 430780
entity reference: P38859
name: DNA replication ATP-dependent helicase/nuclease DNA2
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7522481 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7522481
db: intact

rpd3-rxt2-1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-8430 imex-primary
xref: UnificationXref mint MINT-2208572
xref: RelationshipXref intact EBI-7538250 identity
evidence: Evidence 3da17c29-5c89-4a5b-9cb4-52e22b3607fb IM-15332-8430 433337 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.961
comment: comment:mint
comment: author-confidence:z-score: 1.71514069700252
data source: intact
participant: Protein uniprotkb P32561 identity 1529029543072
participant: Protein uniprotkb P38255 identity 1529029543073

UnificationXref mint MINT-2196078
type: UnificationXref
id: MINT-2196078
db: mint

Evidence 89ba9cc1-1dde-4830-af52-4118723e55ed IM-15332-400 432365 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

Evidence 5adc8d55-f461-468c-a873-8c224014abba IM-15332-4788 433021 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpa43-rpa190-2
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-9205 imex-primary
xref: RelationshipXref intact EBI-7523877 identity
xref: UnificationXref mint MINT-2201822
evidence: Evidence 3a3e30bd-91df-4eac-8b6e-0f85a3007e3a IM-15332-9205 431849 430156
interaction type: physical association
comment: author-confidence:z-score: 2.70630251907391
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: rpa1_yeast
participant: Protein uniprotkb P46669 identity 1529029542329

UnificationXref mint MINT-2203767
type: UnificationXref
id: MINT-2203767
db: mint

RelationshipXref go GO 0006486
type: RelationshipXref
id: GO:0006486
db: gene ontology

ExperimentalForm cae2fd8e-14d6-48c6-ad2d-f8efcfcf33f1
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm f2bb4ec6-a04d-4d03-91e2-3946956cd315
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7537607 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7537607
db: intact

Evidence 712f7b21-919e-4ff4-bcb1-0e631c821298 IM-15332-5166 430477 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rlf2_yeast
type: Protein
evidence: Evidence 853e8f9e-5035-4e1e-bc11-e92984a8022f p 431130
entity reference: Q12495
name: Chromatin assembly factor 1 subunit p90
comment: psi-mi participant
data source: intact

Evidence c1d33832-7a1c-472f-9e58-f80a2693c327 IM-15332-6376 431789 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

dna2_yeast
type: Protein
evidence: Evidence d332c32a-2a9f-4a3c-b09c-38ba244aba32 p 430748
entity reference: P38859
name: DNA replication ATP-dependent helicase/nuclease DNA2
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-11640 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-11640
db: imex

UnificationXref uniprot knowledgebase Q12250
type: UnificationXref
id: Q12250
db: uniprot knowledgebase

RelationshipXref go GO 0006470
type: RelationshipXref
id: GO:0006470
db: gene ontology

rpd3-rxt2-1
type: MolecularInteraction
xref: UnificationXref mint MINT-2208518
xref: RelationshipXref imex IM-15332-9214 imex-primary
xref: RelationshipXref intact EBI-7538170 identity
evidence: Evidence 10127242-5825-4f4b-9567-2d36168be54e IM-15332-9214 433325 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.961
comment: author-confidence:z-score: 3.20640357656355
comment: comment:mint
data source: intact
participant: Protein uniprotkb P38255 identity 1529029543067
participant: rpd3_yeast

UnificationXref uniprot knowledgebase P38431
type: UnificationXref
id: P38431
db: uniprot knowledgebase

RelationshipXref intact EBI-7529515 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7529515
db: intact

RelationshipXref sgd S000001501
type: RelationshipXref
id: S000001501
db: sgd

Evidence 09cbc304-668d-42d4-82b4-40650db54c70 IM-15332-7652 433721 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

Evidence b24a0051-5de2-4ae9-b99e-82b4233eb3e6 IM-15332-4762 430445 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

tho2-thp2-3
type: MolecularInteraction
xref: UnificationXref mint MINT-2199392
xref: RelationshipXref imex IM-15332-2347 imex-primary
xref: RelationshipXref intact EBI-7520289 identity
evidence: Evidence 7d4365ed-4672-4277-87f8-de62b9918a2b IM-15332-2347 431309 430156
interaction type: physical association
comment: author-confidence:z-score: 9.49935425425446
comment: comment:mint
comment: author-confidence:reliability score: 0.495
data source: intact
participant: Protein uniprotkb P53552 identity 1529029542058
participant: Protein uniprotkb O13539 identity 1529029542059

RelationshipXref go GO 0006468
type: RelationshipXref
id: GO:0006468
db: gene ontology

dna2_yeast
type: Protein
evidence: Evidence 3c1d1f69-2405-42c1-9aca-8a2c8d02fd92 p 430728
entity reference: P38859
name: DNA replication ATP-dependent helicase/nuclease DNA2
comment: psi-mi participant
data source: intact

dna2_yeast
type: Protein
evidence: Evidence 9218b1c6-5903-4f8d-b2c0-d936aa949fcf p 430724
entity reference: P38859
name: DNA replication ATP-dependent helicase/nuclease DNA2
comment: psi-mi participant
data source: intact

dna2_yeast
type: Protein
evidence: Evidence fa8da686-708d-4503-8f57-138536c22e5d p 430718
entity reference: P38859
name: DNA replication ATP-dependent helicase/nuclease DNA2
comment: psi-mi participant
data source: intact

RelationshipXref go GO 0090262
type: RelationshipXref
id: GO:0090262
db: gene ontology

RelationshipXref rcsb pdb 2L9B
type: RelationshipXref
id: 2L9B
db: protein data bank

RelationshipXref intact EBI-7515775 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7515775
db: intact

rpc34-rpo26
type: MolecularInteraction
xref: UnificationXref mint MINT-2206808
xref: RelationshipXref intact EBI-7534580 identity
xref: RelationshipXref imex IM-15332-4785 imex-primary
evidence: Evidence 7b3469ee-17a6-432a-91f3-394ef12e575d IM-15332-4785 432945 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 1.83037095799533
comment: comment:mint
comment: author-confidence:reliability score: 0.362
data source: intact
participant: rpc6_yeast
participant: Protein uniprotkb P20435 identity 1529029542877

rpc6_yeast
type: Protein
evidence: Evidence f2a1c35f-cdbe-47d5-b59c-766bf09cc26c p 432975
entity reference: P32910
name: DNA-directed RNA polymerase III subunit RPC6
comment: psi-mi participant
data source: intact

Evidence 834b7d4f-052c-4f2d-8655-7b243fc178df IM-15332-10037 433317 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm 730df568-3247-41f6-8c1c-7a03d838629c
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref imex IM-15332-12473 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12473
db: imex

RelationshipXref go GO 0070941
type: RelationshipXref
id: GO:0070941
db: gene ontology

RelationshipXref go GO 0070940
type: RelationshipXref
id: GO:0070940
db: gene ontology

rpc40-rpa190-3
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-6787 imex-primary
xref: RelationshipXref intact EBI-7535685 identity
xref: UnificationXref mint MINT-2207366
evidence: Evidence 37eaf9eb-7bb6-4193-ad22-f72f230fe086 IM-15332-6787 433069 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 0.433254847869478
comment: comment:mint
comment: author-confidence:reliability score: 0.97
data source: intact
participant: Protein uniprotkb P07703 identity 1529029542938
participant: rpa1_yeast

RelationshipXref go GO 0006452
type: RelationshipXref
id: GO:0006452
db: gene ontology

RelationshipXref dip DIP-1659N
type: RelationshipXref
id: DIP-1659N
db: database of interacting proteins

RelationshipXref go GO 0006450
type: RelationshipXref
id: GO:0006450
db: gene ontology

RelationshipXref intact EBI-7518486 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7518486
db: intact

RelationshipXref intact EBI-7534711 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7534711
db: intact

copb2_yeast
type: Protein
evidence: Evidence eccb2897-4cd2-4ab4-a7b6-7cd538291ed3 p 430642
entity reference: P41811
name: Coatomer subunit beta'
comment: psi-mi participant
data source: intact

rpa190-rpa135-20
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-8023 imex-primary
xref: RelationshipXref intact EBI-7523520 identity
xref: UnificationXref mint MINT-2201588
evidence: Evidence ab3ca63c-abf5-4841-97f9-e385509b71cb IM-15332-8023 431797 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 4.29490116478604
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P10964 identity 1529029542302
participant: Protein uniprotkb P22138 identity 1529029542303

RelationshipXref go GO 0070933
type: RelationshipXref
id: GO:0070933
db: gene ontology

RelationshipXref go GO 0070932
type: RelationshipXref
id: GO:0070932
db: gene ontology

dna2_yeast
type: Protein
evidence: Evidence 68859cdb-4e1e-44b1-a408-9b5b4af69fec p 430690
entity reference: P38859
name: DNA replication ATP-dependent helicase/nuclease DNA2
comment: psi-mi participant
data source: intact

RelationshipXref go GO 0006446
type: RelationshipXref
id: GO:0006446
db: gene ontology

RelationshipXref dip DIP-1658N
type: RelationshipXref
id: DIP-1658N
db: database of interacting proteins

copd_yeast
type: Protein
evidence: Evidence f1802515-253d-4b65-8063-1f2aed007ac3 p 430631
entity reference: P43621
name: Coatomer subunit delta
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7522242 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7522242
db: intact

rnr4-rnr2-4
type: MolecularInteraction
xref: RelationshipXref intact EBI-7521202 identity
xref: RelationshipXref imex IM-15332-3979 imex-primary
xref: UnificationXref mint MINT-2200058
evidence: Evidence 47dfc23a-546f-498b-a920-cc647a39e392 IM-15332-3979 431457 430156
interaction type: physical association
comment: author-confidence:z-score: 6.91206514192721
comment: author-confidence:reliability score: 0.877
comment: comment:mint
data source: intact
participant: Protein uniprotkb P49723 identity 1529029542132
participant: Protein uniprotkb P09938 identity 1529029542133

rpc19-sgv1
type: MolecularInteraction
xref: RelationshipXref intact EBI-7533014 identity
xref: RelationshipXref imex IM-15332-10032 imex-primary
xref: UnificationXref mint MINT-2206141
evidence: Evidence 88a0e59d-2f75-4cec-8043-6f4807c44232 IM-15332-10032 432797 430156
interaction type: physical association
comment: comment:mint
comment: author-confidence:z-score: -0.0970307936358124
comment: author-confidence:reliability score: 0.495
data source: intact
participant: Protein uniprotkb P28000 identity 1529029542802
participant: Protein uniprotkb P23293 identity 1529029542803

RelationshipXref reactome R-SCE-450408
type: RelationshipXref
id: R-SCE-450408
db: reactome

Evidence 6953e978-7f04-4931-b86c-82c685257114 IM-15332-3590 432681 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref go GO 0005096
type: RelationshipXref
id: GO:0005096
db: gene ontology

RelationshipXref reactome R-SCE-2559582
type: RelationshipXref
id: R-SCE-2559582
db: reactome

ExperimentalForm ac88eeda-b0c3-4591-9574-3954ecaea055
type: ExperimentalForm
experimental feature: ModificationFeature 2256b873-d4b9-4fc1-963b-9242cf22386e 432356
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 86f3fd5d-ca71-40b0-a1b5-910466da3735
type: ExperimentalForm
experimental feature: ModificationFeature 3fa824ed-d7f0-4958-8b54-16f175e3b6e2 432996
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 2cfcc57f-baf3-4617-a3e3-10677b1bbd82
type: ExperimentalForm
experimental feature: ModificationFeature a9deed9b-9b07-4038-8218-b224b2d93735 431164
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpg1-osh2
type: MolecularInteraction
xref: UnificationXref mint MINT-2209058
xref: RelationshipXref imex IM-15332-2760 imex-primary
xref: RelationshipXref intact EBI-7539017 identity
evidence: Evidence fb2818a1-c006-48eb-a370-14c9bff4a5e0 IM-15332-2760 433445 430156
interaction type: physical association
comment: author-confidence:z-score: 1.6520342915986
comment: author-confidence:reliability score: 0.796
comment: comment:mint
data source: intact
participant: Protein uniprotkb P38249 identity 1529029543126
participant: Protein uniprotkb Q12451 identity 1529029543127

rpn8_yeast
type: Protein
evidence: Evidence f32f0c04-8419-4174-a76b-eddc20cdd387 p 433858
entity reference: Q08723
name: 26S proteasome regulatory subunit RPN8
comment: psi-mi participant
data source: intact

rpa190-rpa135-6
type: MolecularInteraction
xref: UnificationXref mint MINT-2200940
xref: RelationshipXref imex IM-15332-12051 imex-primary
xref: RelationshipXref intact EBI-7522597 identity
evidence: Evidence 62c3137d-89a2-49e5-8854-0bc630541271 IM-15332-12051 431653 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:z-score: 3.92453451557312
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P22138 identity 1529029542230
participant: rpa1_yeast

RelationshipXref imex IM-15332-5180 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5180
db: imex

ref2-swd2-1
type: MolecularInteraction
xref: UnificationXref mint MINT-2195519
xref: RelationshipXref imex IM-15332-5165 imex-primary
xref: RelationshipXref intact EBI-7515395 identity
evidence: Evidence 2707bd8a-e6fd-4035-944d-b0179789f73c IM-15332-5165 430449 430156
interaction type: physical association
comment: comment:mint
comment: author-confidence:reliability score: 0.99
comment: author-confidence:z-score: 8.91344879741462
data source: intact
participant: Protein uniprotkb P42073 identity 1529029541629
participant: Protein uniprotkb P36104 identity 1529029541628

Evidence 73fbda05-ea67-47c9-8565-ee50dc516faa IM-15332-3998 433625 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpb9-rpb7
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-2358 imex-primary
xref: UnificationXref mint MINT-2204346
xref: RelationshipXref intact EBI-7529812 identity
evidence: Evidence a0f1b09c-893c-4265-8d17-7bc7e519d41d IM-15332-2358 432409 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.989
comment: author-confidence:z-score: 7.23622842310685
comment: comment:mint
data source: intact
participant: Protein uniprotkb P27999 identity 1529029542609
participant: rpb7_yeast

ExperimentalForm 2946ff7c-8c81-4ec4-b8ef-52cc43df82dd
type: ExperimentalForm
experimental feature: ModificationFeature 1078965a-ca7d-40f7-933d-32ec0eb77480 430604
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref refseq NP 010223 1
type: RelationshipXref
id: NP_010223.1
db: refseq

RelationshipXref go GO 0005089
type: RelationshipXref
id: GO:0005089
db: gene ontology

RelationshipXref go GO 0005088
type: RelationshipXref
id: GO:0005088
db: gene ontology

RelationshipXref go GO 0005087
type: RelationshipXref
id: GO:0005087
db: gene ontology

cope_yeast
type: Protein
evidence: Evidence cf2990f3-4a3c-4258-ba0a-3bfc942f0309 p 430610
entity reference: P40509
name: Coatomer subunit epsilon
comment: psi-mi participant
data source: intact

RelationshipXref go GO 0005085
type: RelationshipXref
id: GO:0005085
db: gene ontology

Evidence ad34cb81-b877-43be-b544-f46b53801eb7 IM-15332-10426 430617 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref intact EBI-7527742 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7527742
db: intact

RelationshipXref interpro IPR018255
type: RelationshipXref
id: IPR018255
db: interpro

RelationshipXref intact EBI-7517918 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7517918
db: intact

RelationshipXref uniprotkb D6VQB6 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VQB6
db: uniprot knowledgebase

RelationshipXref intact EBI-1797 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-1797
db: intact

Evidence e1bf68e5-8f25-472a-8144-d9959a525f5e IM-15332-12054 432049 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rnr4-rnr2-9
type: MolecularInteraction
xref: RelationshipXref intact EBI-7521297 identity
xref: UnificationXref mint MINT-2200148
xref: RelationshipXref imex IM-15332-4771 imex-primary
evidence: Evidence f559fbf3-f72f-4745-b886-5ee376a9e330 IM-15332-4771 431477 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.877
comment: author-confidence:z-score: 0.329064463756996
comment: comment:mint
data source: intact
participant: Protein uniprotkb P49723 identity 1529029542142
participant: Protein uniprotkb P09938 identity 1529029542143

ExperimentalForm 4b61651b-41c3-49ac-8fbd-d49867f02f0f
type: ExperimentalForm
experimental feature: ModificationFeature 5eb9950e-d268-411c-bc04-d6331d37a2c7 430819
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-7642 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-7642
db: imex

Evidence 71541345-7fdb-4f48-8903-450ea1bdcfa1 IM-15332-5578 430565 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref dip DIP-2100N
type: RelationshipXref
id: DIP-2100N
db: database of interacting proteins

RelationshipXref go GO 0006413
type: RelationshipXref
id: GO:0006413
db: gene ontology

rpg1-tif34-3
type: MolecularInteraction
xref: RelationshipXref intact EBI-7539832 identity
xref: RelationshipXref imex IM-15332-7209 imex-primary
xref: UnificationXref mint MINT-2209400
evidence: Evidence 7a98d482-b4fa-43e2-b77a-3bebff780a54 IM-15332-7209 433521 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.972
comment: author-confidence:z-score: 9.66134277083959
data source: intact
participant: Protein uniprotkb P38249 identity 1529029543164
participant: Protein uniprotkb P40217 identity 1529029543165

Evidence 5570d32d-6ce5-4505-bf3d-ed417c467c06 IM-15332-9617 432761 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref mint P04807
type: RelationshipXref
id: P04807
db: mint

UnificationXref uniprot knowledgebase P16370
type: UnificationXref
id: P16370
db: uniprot knowledgebase

rfa2-rfa1-2
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-3157 imex-primary
xref: RelationshipXref intact EBI-7516990 identity
xref: UnificationXref mint MINT-2196906
evidence: Evidence 8cca6e1c-1bf3-48dd-ba5d-6b184ca1e10a IM-15332-3157 430757 430156
interaction type: physical association
comment: author-confidence:z-score: 0.446616817678336
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P26754 identity 1529029541782
participant: rfa1_yeast

ExperimentalForm 4d490293-cadb-4cbf-bb83-cf55a480749f
type: ExperimentalForm
experimental feature: ModificationFeature 70fb865e-7cea-46e6-8a82-cb2438e00fb4 433192
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7520779 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7520779
db: intact

RelationshipXref go GO 0006409
type: RelationshipXref
id: GO:0006409
db: gene ontology

Evidence afe347b8-dd12-4954-918c-a69b7c235f96 IM-15332-9621 433181 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref go GO 0006407
type: RelationshipXref
id: GO:0006407
db: gene ontology

RelationshipXref go GO 0006406
type: RelationshipXref
id: GO:0006406
db: gene ontology

rpn8_yeast
type: Protein
evidence: Evidence 580fb9c5-be7b-442a-a0bc-cc1b3ab673e2 p 433916
entity reference: Q08723
name: 26S proteasome regulatory subunit RPN8
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2207870
type: UnificationXref
id: MINT-2207870
db: mint

RelationshipXref go GO 0006401
type: RelationshipXref
id: GO:0006401
db: gene ontology

Evidence 19a23be4-0b95-4607-811f-99d419b8e65e IM-15332-10845 430717 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

atr_yeast
type: Protein
evidence: Evidence 4d7ec174-4e2c-457f-bc3a-470afacbf6c8 p 431978
entity reference: P38111
name: Serine/threonine-protein kinase MEC1
comment: psi-mi participant
data source: intact

Evidence 84169012-a97c-441e-bbf5-3333a328d7d8 IM-15332-398 432305 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref mint MINT-2200310
type: UnificationXref
id: MINT-2200310
db: mint

ExperimentalForm c26ce691-4bec-41bf-8c2e-9dcebf238cfc
type: ExperimentalForm
experimental feature: ModificationFeature fa4bcdb8-af5a-427b-969c-5c7341ac9dfa 431324
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 10455082-9785-4efb-ac9c-2be9fc7d5301
type: ExperimentalForm
experimental feature: ModificationFeature 6cb27810-ed12-4208-b5a2-8ef1559f297e 433559
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref interpro IPR013907
type: RelationshipXref
id: IPR013907
db: interpro

RelationshipXref go GO 0034399
type: RelationshipXref
id: GO:0034399
db: gene ontology

Evidence 052c500c-d536-4f67-a5a7-adda6a74705d IM-15332-1947 430433 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref intact EBI-15251 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-15251
db: intact

rpa190-rpa49-4
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-2743 imex-primary
xref: RelationshipXref intact EBI-7522533 identity
xref: UnificationXref mint MINT-2200868
evidence: Evidence dc56353c-6efb-437c-8168-60cc18a98842 IM-15332-2743 431637 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.983
comment: comment:mint
comment: author-confidence:z-score: 1.31086636619443
data source: intact
participant: rpa1_yeast
participant: Protein uniprotkb Q01080 identity 1529029542222

Evidence e71feec3-e79d-4b23-83c8-00ca756ea8df IM-15332-9198 431165 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref intact EBI-7517660 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7517660
db: intact

RelationshipXref imex IM-15332-10024 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-10024
db: imex

UnificationXref mint MINT-2207852
type: UnificationXref
id: MINT-2207852
db: mint

rpb9-rpo21-11
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-9614 imex-primary
xref: UnificationXref mint MINT-2205277
xref: RelationshipXref intact EBI-7531702 identity
evidence: Evidence 93d2ac96-76d6-4bce-b81a-f1bf5a09515c IM-15332-9614 432605 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 0.109166228518241
comment: comment:mint
comment: author-confidence:reliability score: 0.944
data source: intact
participant: Protein uniprotkb P27999 identity 1529029542706
participant: Protein uniprotkb P04050 identity 1529029542707

rpb10-rpa135-7
type: MolecularInteraction
xref: RelationshipXref intact EBI-7524806 identity
xref: UnificationXref mint MINT-2202471
xref: RelationshipXref imex IM-15332-2353 imex-primary
evidence: Evidence c881be99-c5fa-40fd-8f7c-03ca55577e47 IM-15332-2353 431993 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.932
comment: comment:mint
comment: author-confidence:z-score: 0.88335328610349
data source: intact
participant: rpab5_yeast
participant: Protein uniprotkb P22138 identity 1529029542400

RelationshipXref uniprotkb D3DLS4 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D3DLS4
db: uniprot knowledgebase

ExperimentalForm 55226fea-e345-4537-a215-3ad6c132800a
type: ExperimentalForm
experimental feature: ModificationFeature cabb1d84-a857-4531-9242-77fc0b3ac6af 433715
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref interpro IPR026896
type: RelationshipXref
id: IPR026896
db: interpro

RelationshipXref rcsb pdb 2L0I
type: RelationshipXref
id: 2L0I
db: protein data bank

RelationshipXref interpro IPR015256
type: RelationshipXref
id: IPR015256
db: interpro

UnificationXref uniprot knowledgebase P32910
type: UnificationXref
id: P32910
db: uniprot knowledgebase

RelationshipXref imex IM-15332-817 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-817
db: imex

rpa190-rpa135-15
type: MolecularInteraction
xref: RelationshipXref intact EBI-7523232 identity
xref: RelationshipXref imex IM-15332-7199 imex-primary
xref: UnificationXref mint MINT-2201336
evidence: Evidence 80614a2d-ec99-47a6-85be-7d50c3c8fe7f IM-15332-7199 431741 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 3.50672463361368
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P22138 identity 1529029542275
participant: rpa1_yeast

RelationshipXref intact EBI-7528943 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7528943
db: intact

RelationshipXref intact EBI-7521061 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7521061
db: intact

UnificationXref mint MINT-2207834
type: UnificationXref
id: MINT-2207834
db: mint

ExperimentalForm 629eee44-0d42-4543-85a3-091d87f14d2d
type: ExperimentalForm
experimental feature: ModificationFeature 1f382d50-ec76-4f42-bcd4-a8f1d3a038c3 431951
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

atr_yeast
type: Protein
evidence: Evidence 269b5812-665f-4c7a-b106-a3a7bdfd2f98 p 431912
entity reference: P38111
name: Serine/threonine-protein kinase MEC1
comment: psi-mi participant
data source: intact

prs4_yeast
type: Protein
evidence: Evidence ec64b461-afef-49d9-86a4-59c70279b235 p 433768
entity reference: P40327
name: 26S proteasome regulatory subunit 4 homolog
comment: psi-mi participant
data source: intact

atr_yeast
type: Protein
evidence: Evidence 1fa172ab-0740-486b-bc72-3ff07e3940ef p 431904
entity reference: P38111
name: Serine/threonine-protein kinase MEC1
comment: psi-mi participant
data source: intact

rfa1-rfa3-3
type: MolecularInteraction
xref: UnificationXref mint MINT-2196636
xref: RelationshipXref imex IM-15332-2734 imex-primary
xref: RelationshipXref intact EBI-7516667 identity
evidence: Evidence 5fc87159-b581-459e-828f-c3677e48e5b4 IM-15332-2734 430697 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.988
comment: author-confidence:z-score: 1.65085422588055
comment: comment:mint
data source: intact
participant: rfa3_yeast
participant: rfa1_yeast

prs4_yeast
type: Protein
evidence: Evidence 052a4e6e-dbbb-4cbb-b1ea-0cbe0b956b36 p 433756
entity reference: P40327
name: 26S proteasome regulatory subunit 4 homolog
comment: psi-mi participant
data source: intact

RelationshipXref dip DIP-6650N
type: RelationshipXref
id: DIP-6650N
db: database of interacting proteins

UnificationXref mint MINT-2206483
type: UnificationXref
id: MINT-2206483
db: mint

ExperimentalForm 966f7a5b-b65c-489f-becb-ebc1bf579c77
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpb10-rpc19-1
type: MolecularInteraction
xref: UnificationXref mint MINT-2202759
xref: RelationshipXref imex IM-15332-7202 imex-primary
xref: RelationshipXref intact EBI-7525393 identity
evidence: Evidence d78f7e62-5340-4999-ae53-adaa9848c0cd IM-15332-7202 432057 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 2.23201218768609
comment: author-confidence:reliability score: 0.52
comment: comment:mint
data source: intact
participant: rpab5_yeast
participant: Protein uniprotkb P28000 identity 1529029542432

RelationshipXref interpro IPR026874
type: RelationshipXref
id: IPR026874
db: interpro

ExperimentalForm d39ad6e5-51a9-4980-9da1-7c3442c02f96
type: ExperimentalForm
experimental feature: ModificationFeature b10f2660-f4e1-4b13-9937-832c3e79ecb8 432019
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 404b721b-a934-433d-a02d-012c45cdd48f
type: ExperimentalForm
experimental feature: ModificationFeature 4327ff83-1b1b-48ce-9aac-dea7e7e6d8f1 431276
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

Evidence ff65f058-2509-4c11-8273-ee2514886030 IM-15332-8018 431201 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

atr_yeast
type: Protein
evidence: Evidence b3c54987-9eef-4f3a-ab79-08aa93cb7420 p 431890
entity reference: P38111
name: Serine/threonine-protein kinase MEC1
comment: psi-mi participant
data source: intact

prs4_yeast
type: Protein
evidence: Evidence 64527464-2ea6-4c99-bed3-52deca6f6219 p 433742
entity reference: P40327
name: 26S proteasome regulatory subunit 4 homolog
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 1SXJ
type: RelationshipXref
id: 1SXJ
db: protein data bank

RelationshipXref intact EBI-7516737 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7516737
db: intact

RelationshipXref rcsb pdb 2KM8
type: RelationshipXref
id: 2KM8
db: protein data bank

RelationshipXref reactome R-SCE-5655862
type: RelationshipXref
id: R-SCE-5655862
db: reactome

ExperimentalForm d5eb7a18-c228-4f2e-9b4b-6c51896d8da3
type: ExperimentalForm
experimental feature: ModificationFeature e431efa8-26aa-4c82-9a20-cd68fa98bb34 430855
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

atg11_yeast
type: Protein
evidence: Evidence b04fb99a-0457-443e-87ae-b13d8f32deaa p 431590
entity reference: atg11_yeast
name: Autophagy-related protein 11
comment: psi-mi participant
data source: intact

pp12_yeast
type: ProteinReference
sequence: MDSQPVDVDNIIDRLLEVRGSKPGQQVDLEENEIRYLCSKARSIFIKQPILLELEAPIKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIIDEKIFCMHGGLSPDLNSMEQIRRVMRPTDIPDVGLLCDLLWSDPDKDIVGWSENDRGVSFTFGPDVVNRFLQKQDMELICRAHQVVEDGYEFFSKRQLVTLFSAPNYCGEFDNAGAMMSVDESLLCSFQILKPAQKSLPRQAGGRKKK
xref: RelationshipXref go GO 0009408
xref: RelationshipXref go GO 0035307
xref: RelationshipXref uniprotkb D3DM39 secondary-ac
xref: RelationshipXref go GO 0006986
xref: RelationshipXref go GO 0005935
xref: RelationshipXref go GO 1901901
xref: RelationshipXref go GO 0006873
xref: RelationshipXref interpro IPR029052
xref: RelationshipXref go GO 0030847
xref: RelationshipXref go GO 0030846
xref: RelationshipXref go GO 0061587
xref: RelationshipXref go GO 1903501
xref: RelationshipXref go GO 0007059
xref: RelationshipXref interpro IPR004843
xref: RelationshipXref go GO 0004722
xref: RelationshipXref go GO 0051726
xref: RelationshipXref go GO 0005816
xref: RelationshipXref interpro IPR037981
xref: RelationshipXref go GO 0000778
xref: RelationshipXref mint P32598
xref: UnificationXref uniprot knowledgebase P32598
xref: RelationshipXref go GO 0006109
xref: RelationshipXref go GO 0070940
xref: RelationshipXref refseq NP 011059 3
xref: RelationshipXref interpro IPR031675
xref: RelationshipXref go GO 0031297
xref: RelationshipXref go GO 0046872
xref: RelationshipXref go GO 0005730
xref: RelationshipXref go GO 0005977
xref: RelationshipXref go GO 0000077
xref: RelationshipXref go GO 0000076
xref: RelationshipXref dip DIP-1336N
xref: RelationshipXref go GO 0034501
xref: RelationshipXref sgd S000000935
xref: RelationshipXref intact EBI-13715 identity
xref: RelationshipXref interpro IPR006186
xref: RelationshipXref go GO 0007094
xref: RelationshipXref go GO 0006470
xref: RelationshipXref go GO 0006364
xref: RelationshipXref go GO 0000903
xref: RelationshipXref go GO 0032153
xref: RelationshipXref go GO 0005634
xref: RelationshipXref go GO 0007346
xref: RelationshipXref go GO 0000164
xref: RelationshipXref go GO 0005847
xref: RelationshipXref go GO 0006397
xref: RelationshipXref go GO 0051321
xref: RelationshipXref go GO 0030437
xref: RelationshipXref go GO 0016576
xref: RelationshipXref go GO 0001400
xref: RelationshipXref go GO 0007114
organism: http://identifiers.org/taxonomy/559292
name: DIS2
name: GLC7
name: Serine/threonine-protein phosphatase PP1-2
name: CID1
name: YER133W

UnificationXref mint MINT-2195790
type: UnificationXref
id: MINT-2195790
db: mint

prs4_yeast
type: Protein
evidence: Evidence 15fa38cf-f703-4f74-8f30-858123f01d99 p 433720
entity reference: P40327
name: 26S proteasome regulatory subunit 4 homolog
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2201714
type: UnificationXref
id: MINT-2201714
db: mint

rpc6_yeast
type: Protein
evidence: Evidence bae76148-34d7-49a7-ab73-899e8c2b13c1 p 432744
entity reference: P32910
name: DNA-directed RNA polymerase III subunit RPC6
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2206465
type: UnificationXref
id: MINT-2206465
db: mint

rpc6_yeast
type: Protein
evidence: Evidence 59dcf526-5c24-4275-95b3-965eed63bd9a p 432736
entity reference: P32910
name: DNA-directed RNA polymerase III subunit RPC6
comment: psi-mi participant
data source: intact

ExperimentalForm fc693b3b-ad60-467a-b9e5-5b48396336aa
type: ExperimentalForm
experimental feature: ModificationFeature 60f137af-f709-431a-9f7e-80699de063f9 432572
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref refseq NP 011771 1
type: RelationshipXref
id: NP_011771.1
db: refseq

rpc8_yeast
type: Protein
evidence: Evidence 4f1c0431-8ba8-4ed5-b5d0-4eaec17ab500 p 432684
entity reference: P35718
name: DNA-directed RNA polymerase III subunit RPC8
comment: psi-mi participant
data source: intact

rpc8_yeast
type: Protein
evidence: Evidence 99424987-2b85-4a50-aec8-190bf568e7d9 p 432680
entity reference: P35718
name: DNA-directed RNA polymerase III subunit RPC8
comment: psi-mi participant
data source: intact

RelationshipXref interpro IPR026851
type: RelationshipXref
id: IPR026851
db: interpro

RelationshipXref rcsb pdb 3OEV
type: RelationshipXref
id: 3OEV
db: protein data bank

RelationshipXref rcsb pdb 3OEU
type: RelationshipXref
id: 3OEU
db: protein data bank

ExperimentalForm 227b5667-fdf8-4436-8c3c-59e20e5dbb37
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

Evidence 987ba29b-8e57-4676-bcd7-eb23dd570f6e IM-15332-10035 432921 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

Evidence 054228d6-d0ec-4f9c-a4e3-73a8cb00a0a1 IM-15332-2362 433209 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref imex IM-15332-6365 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-6365
db: imex

med18_yeast
type: ProteinReference
sequence: MVQQLSLFGSIGDDGYDLLISTLTTISGNPPLLYNSLCTVWKPNPSYDVENVNSRNQLVEPNRIKLSKEVPFSYLIDETMMDKPLNFRILKSFTNDKIPLNYAMTRNILHNTVPQVTNFNSTNEDQNNSKHTEDTVNESRNSDDIIDVDMDASPAPSNESCSPWSLQISDIPAAGNNRSVSMQTIAETIILSSAGKNSSVSSLMNGLGYVFEFQYLTIGVKFFMKHGLILELQKIWQIEEAGNSQITSGGFLLKAYINVSRGTDIDRINYTETALMNLKKELQGYIELSVPDRQSMDSRVAHGNILI
xref: RelationshipXref go GO 0051123
xref: RelationshipXref mint P32585
xref: RelationshipXref rcsb pdb 4GWP
xref: RelationshipXref go GO 0001129
xref: RelationshipXref interpro IPR019095
xref: RelationshipXref uniprotkb D6VUN6 secondary-ac
xref: RelationshipXref go GO 0000979
xref: RelationshipXref go GO 0006369
xref: RelationshipXref go GO 0070847
xref: RelationshipXref go GO 0045944
xref: RelationshipXref rcsb pdb 4GWQ
xref: RelationshipXref uniprotkb Q6B1R3 secondary-ac
xref: RelationshipXref go GO 0001113
xref: RelationshipXref rcsb pdb 2HZM
xref: RelationshipXref rcsb pdb 5SVA
xref: RelationshipXref sgd S000003336
xref: RelationshipXref rcsb pdb 4V1O
xref: RelationshipXref rcsb pdb 3J1O
xref: RelationshipXref intact EBI-18032 identity
xref: RelationshipXref rcsb pdb 3RJ1
xref: UnificationXref uniprot knowledgebase P32585
xref: RelationshipXref rcsb pdb 2HZS
xref: RelationshipXref go GO 0001104
xref: RelationshipXref go GO 0000991
xref: RelationshipXref go GO 0001135
xref: RelationshipXref go GO 0016592
xref: RelationshipXref refseq NP 011618 3
xref: RelationshipXref dip DIP-1658N
organism: http://identifiers.org/taxonomy/559292
name: YGR104C
name: MED18
name: Mediator complex subunit 18
name: Mediator of RNA polymerase II transcription subunit 18
name: SRB5
name: Suppressor of RNA polymerase B 5

prs4_yeast
type: Protein
evidence: Evidence dbd70ddc-4de8-4364-90e6-c58e4a1ebbd8 p 433700
entity reference: P40327
name: 26S proteasome regulatory subunit 4 homolog
comment: psi-mi participant
data source: intact

UnificationXref uniprot knowledgebase P43620
type: UnificationXref
id: P43620
db: uniprot knowledgebase

Evidence 63dbdaaf-e69b-4da2-a4cc-551d027c2a57 IM-15332-10023 431485 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpc34-rpc82-4
type: MolecularInteraction
xref: UnificationXref mint MINT-2206916
xref: RelationshipXref imex IM-15332-6786 imex-primary
xref: RelationshipXref intact EBI-7534695 identity
evidence: Evidence 4c805978-ed42-49ff-8671-b6a443732155 IM-15332-6786 432969 430156
interaction type: physical association
comment: author-confidence:z-score: 6.51882646616273
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P32910 identity 1529029542889
participant: Protein uniprotkb P32349 identity 1529029542888

ExperimentalForm 8832b69e-22fc-4cfb-be5e-5fb052d36036
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

Evidence 84422c2e-62fb-4691-b795-474e37280a98 IM-15332-7203 432117 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref imex IM-15332-7204 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-7204
db: imex

ExperimentalForm 56f15704-7b88-4614-8b16-e66f87c21eec
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpc8_yeast
type: Protein
evidence: Evidence c6974007-55e3-4dac-85a5-27e03ae7dd52 p 432660
entity reference: P35718
name: DNA-directed RNA polymerase III subunit RPC8
comment: psi-mi participant
data source: intact

ExperimentalForm fc289e98-4b8a-4b3f-9210-3d11fbad4369
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm e0227ac2-f3df-47db-a011-0c723396fd22
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref mint MINT-2195772
type: UnificationXref
id: MINT-2195772
db: mint

UnificationXref mint MINT-2201732
type: UnificationXref
id: MINT-2201732
db: mint

UnificationXref mint MINT-2206447
type: UnificationXref
id: MINT-2206447
db: mint

RelationshipXref imex IM-15332-1208 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1208
db: imex

RelationshipXref intact EBI-7526369 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7526369
db: intact

sld3_yeast
type: Protein
evidence: Evidence 4c1f36bf-480b-42e9-a5da-2833818539cd p 431106
entity reference: sld3_yeast
name: DNA replication regulator SLD3
comment: psi-mi participant
data source: intact

RelationshipXref refseq NP 014985 1
type: RelationshipXref
id: NP_014985.1
db: refseq

med17_yeast
type: ProteinReference
sequence: MTTEDPDSNHLSSETGIKLALDPNLITLALSSNPNSSLHSPTSDEPVPESAGKADTSIRLEGDELENKTKKDNDKNLKFLKNKDSLVSNPHEIYGSMPLEQLIPIILRQRGPGFKFVDLNEKELQNEIKQLGSDSSDGHNSEKKDTDGADENVQIGEDFMEVDYEDKDNPVDSRNETDHKTNENGETDDNIETVMTQEQFVKRRRDMLEHINLAMNESSLALEFVSLLLSSVKESTGMSSMSPFLRKVVKPSSLNSDKIPYVAPTKKEYIELDILNKGWKLQSLNESKDLLRASFNKLSSILQNEHDYWNKIMQSISNKDVIFKIRDRTSGQKLLAIKYGYEDSGSTYKHDRGIANIRNNIESQNLDLIPHSSSVFKGTDFVHSVKKFLRVRIFTKIESEDDYILSGESVMDRDSESEEAETKDIRKQIQLLKKIIFEKELMYQIKKECALLISYGVSIENENKVIIELPNEKFEIELLSLDDDSIVNHEQDLPKINDKRANLMLVMLRLLLVVIFKKTLRSRISSPHGLINLNVDDDILIIRPILGKVRFANYKLLLKKIIKDYVLDIVPGSSITETEVEREQPQENKNIDDENITKLNKEIRAFDKLLNIPRRELKINLPLTEHKSPNLSLMLESPNYCNALIHIKFSAGTEANAVSFDTTFSDFKEVEDFLHFIVAEYIQQKKV
xref: RelationshipXref rcsb pdb 4H62
xref: RelationshipXref interpro IPR019313
xref: RelationshipXref rcsb pdb 4GWQ
xref: RelationshipXref rcsb pdb 4GWP
xref: RelationshipXref refseq NP 010939 1
xref: RelationshipXref uniprotkb Q06790 secondary-ac
xref: RelationshipXref dip DIP-152N
xref: RelationshipXref uniprotkb Q6B1B4 secondary-ac
xref: RelationshipXref go GO 0033613
xref: UnificationXref uniprot knowledgebase P32569
xref: RelationshipXref go GO 0000979
xref: RelationshipXref go GO 0006367
xref: RelationshipXref go GO 0070847
xref: RelationshipXref go GO 0045944
xref: RelationshipXref rcsb pdb 5SVA
xref: RelationshipXref rcsb pdb 4V1O
xref: RelationshipXref rcsb pdb 3J1O
xref: RelationshipXref mint P32569
xref: RelationshipXref rcsb pdb 3RJ1
xref: RelationshipXref sgd S000000824
xref: RelationshipXref go GO 0001139
xref: RelationshipXref go GO 0001104
xref: RelationshipXref go GO 0016592
xref: RelationshipXref intact EBI-18025 identity
xref: RelationshipXref uniprotkb D3DLS1 secondary-ac
organism: http://identifiers.org/taxonomy/559292
name: Suppressor of RNA polymerase B 4
name: YER022W
name: Mediator complex subunit 17
name: MED17
name: Mediator of RNA polymerase II transcription subunit 17
name: SRB4

RelationshipXref imex IM-15332-3995 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-3995
db: imex

rpc40-rpc53
type: MolecularInteraction
xref: UnificationXref mint MINT-2206988
xref: RelationshipXref imex IM-15332-8426 imex-primary
xref: RelationshipXref intact EBI-7534779 identity
evidence: Evidence 117d5ff9-5e20-4fda-b594-6c1b69543d18 IM-15332-8426 432985 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 0.4960112253708
comment: author-confidence:reliability score: 0.983
comment: comment:mint
data source: intact
participant: Protein uniprotkb P07703 identity 1529029542897
participant: Protein uniprotkb P25441 identity 1529029542896

RelationshipXref go GO 0034316
type: RelationshipXref
id: GO:0034316
db: gene ontology

prs4_yeast
type: Protein
evidence: Evidence 795a7294-8db1-45ec-b6e5-c8370cde9d38 p 433662
entity reference: P40327
name: 26S proteasome regulatory subunit 4 homolog
comment: psi-mi participant
data source: intact

rco1-sin3-11
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-12470 imex-primary
xref: UnificationXref mint MINT-2195123
xref: RelationshipXref intact EBI-7514968 identity
evidence: Evidence ec908597-1d0e-4bf1-af4f-a8bf087f6992 IM-15332-12470 430361 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.988
comment: author-confidence:z-score: 2.72637588432647
comment: comment:mint
data source: intact
participant: sin3_yeast
participant: rco1_yeast

rpd3_yeast
type: ProteinReference
sequence: MVYEATPFDPITVKPSDKRRVAYFYDADVGNYAYGAGHPMKPHRIRMAHSLIMNYGLYKKMEIYRAKPATKQEMCQFHTDEYIDFLSRVTPDNLEMFKRESVKFNVGDDCPVFDGLYEYCSISGGGSMEGAARLNRGKCDVAVNYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHPRVLYIDIDVHHGDGVEEAFYTTDRVMTCSFHKYGEFFPGTGELRDIGVGAGKNYAVNVPLRDGIDDATYRSVFEPVIKKIMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMEGHANCVNYVKSFGIPMMVVGGGGYTMRNVARTWCFETGLLNNVVLDKDLPYNEYYEYYGPDYKLSVRPSNMFNVNTPEYLDKVMTNIFANLENTKYAPSVQLNHTPRDAEDLGDVEEDSAEAKDTKGGSQYARDLHVEHDNEFY
xref: RelationshipXref sgd S000005274
xref: RelationshipXref go GO 0000083
xref: RelationshipXref go GO 0001302
xref: RelationshipXref go GO 0031939
xref: RelationshipXref interpro IPR003084
xref: RelationshipXref go GO 0070822
xref: RelationshipXref dip DIP-681N
xref: RelationshipXref go GO 0061587
xref: RelationshipXref go GO 0034503
xref: RelationshipXref go GO 0034399
xref: RelationshipXref go GO 0061188
xref: RelationshipXref go GO 0061186
xref: RelationshipXref reactome R-SCE-3214815
xref: RelationshipXref reactome R-SCE-4551638
xref: RelationshipXref go GO 0045128
xref: RelationshipXref go GO 0000122
xref: RelationshipXref go GO 0016479
xref: RelationshipXref reactome R-SCE-8936459
xref: UnificationXref uniprot knowledgebase P32561
xref: RelationshipXref go GO 0006368
xref: RelationshipXref go GO 0016239
xref: RelationshipXref go GO 0030174
xref: RelationshipXref go GO 0051038
xref: RelationshipXref go GO 0000118
xref: RelationshipXref go GO 0000117
xref: RelationshipXref go GO 0033698
xref: RelationshipXref go GO 0005737
xref: RelationshipXref interpro IPR000286
xref: RelationshipXref interpro IPR023696
xref: RelationshipXref go GO 0032221
xref: RelationshipXref uniprotkb D6W0L7 secondary-ac
xref: RelationshipXref go GO 0004407
xref: RelationshipXref refseq NP 014069 1
xref: RelationshipXref interpro IPR037138
xref: RelationshipXref mint P32561
xref: RelationshipXref go GO 0003714
xref: RelationshipXref go GO 0003713
xref: RelationshipXref intact EBI-15864 identity
xref: RelationshipXref go GO 0032041
xref: RelationshipXref go GO 0070933
xref: RelationshipXref interpro IPR023801
xref: RelationshipXref go GO 0070932
xref: RelationshipXref go GO 0045944
organism: http://identifiers.org/taxonomy/559292
name: REC3
name: Transcriptional regulatory protein RPD3
name: RPD3
name: MOF6
name: SDI2
name: YNL330C
name: N0305
name: Histone deacetylase RPD3
name: SDS6

Evidence 9e7f5c95-4184-4a55-b5a0-11b92d31af94 IM-15332-11647 433301 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref imex IM-15332-12488 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12488
db: imex

rpa190-rpa34-1
type: MolecularInteraction
xref: UnificationXref mint MINT-2201318
xref: RelationshipXref intact EBI-7523193 identity
xref: RelationshipXref imex IM-15332-4774 imex-primary
evidence: Evidence 9b860cb4-1cf2-47ce-bb16-a94a36c214ac IM-15332-4774 431737 430156
interaction type: physical association
comment: comment:mint
comment: author-confidence:z-score: 2.55670188786017
comment: author-confidence:reliability score: 0.733
data source: intact
participant: rpa1_yeast
participant: Protein uniprotkb P47006 identity 1529029542272

RelationshipXref refseq NP 013216 1
type: RelationshipXref
id: NP_013216.1
db: refseq

RelationshipXref rcsb pdb 5VVS
type: RelationshipXref
id: 5VVS
db: protein data bank

RelationshipXref rcsb pdb 5VVR
type: RelationshipXref
id: 5VVR
db: protein data bank

prs4_yeast
type: Protein
evidence: Evidence d093e6b5-aa8c-45e1-b336-e5cf7e1ab242 p 433650
entity reference: P40327
name: 26S proteasome regulatory subunit 4 homolog
comment: psi-mi participant
data source: intact

prs4_yeast
type: Protein
evidence: Evidence c1dee5f8-0078-4148-bfb5-86eab30311d8 p 433648
entity reference: P40327
name: 26S proteasome regulatory subunit 4 homolog
comment: psi-mi participant
data source: intact

rpc40-rpa190-4
type: MolecularInteraction
xref: RelationshipXref intact EBI-7536137 identity
xref: RelationshipXref imex IM-15332-10036 imex-primary
xref: UnificationXref mint MINT-2207726
evidence: Evidence a554b735-fa58-4d3b-9186-06ab898405c4 IM-15332-10036 433149 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 2.65316319369586
comment: comment:mint
comment: author-confidence:reliability score: 0.97
data source: intact
participant: rpa1_yeast
participant: Protein uniprotkb P07703 identity 1529029542979

prs4_yeast
type: Protein
evidence: Evidence 1d640ea5-1e96-4e33-97b3-977e9422b127 p 433638
entity reference: P40327
name: 26S proteasome regulatory subunit 4 homolog
comment: psi-mi participant
data source: intact

Evidence fab18d1e-ad91-434f-b946-731f5ffbd7c1 IM-15332-3171 432205 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref intact EBI-7536827 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7536827
db: intact

RelationshipXref imex IM-15332-386 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-386
db: imex

RelationshipXref interpro IPR013953
type: RelationshipXref
id: IPR013953
db: interpro

Evidence c75062d4-3843-48ee-91c4-ebd241ca2807 IM-15332-11238 431125 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref mint MINT-2205078
type: UnificationXref
id: MINT-2205078
db: mint

RelationshipXref go GO 0005768
type: RelationshipXref
id: GO:0005768
db: gene ontology

UnificationXref mint MINT-2201768
type: UnificationXref
id: MINT-2201768
db: mint

Evidence d78f7e62-5340-4999-ae53-adaa9848c0cd IM-15332-7202 432057 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref rcsb pdb 5W5Y
type: RelationshipXref
id: 5W5Y
db: protein data bank

UnificationXref mint MINT-2206411
type: UnificationXref
id: MINT-2206411
db: mint

RelationshipXref rcsb pdb 5W66
type: RelationshipXref
id: 5W66
db: protein data bank

RelationshipXref rcsb pdb 5W65
type: RelationshipXref
id: 5W65
db: protein data bank

RelationshipXref rcsb pdb 5W64
type: RelationshipXref
id: 5W64
db: protein data bank

UnificationXref mint MINT-2195736
type: UnificationXref
id: MINT-2195736
db: mint

UnificationXref mint MINT-2205060
type: UnificationXref
id: MINT-2205060
db: mint

ret1-rpc40
type: MolecularInteraction
xref: RelationshipXref intact EBI-7515614 identity
xref: RelationshipXref imex IM-15332-385 imex-primary
xref: UnificationXref mint MINT-2195754
evidence: Evidence 28419591-7f01-4b3b-84f3-3096ba44365a IM-15332-385 430501 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 8.03370308600683
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P07703 identity 1529029541654
participant: Protein uniprotkb P22276 identity 1529029541655

ret1-rpc53-4
type: MolecularInteraction
xref: RelationshipXref intact EBI-7515838 identity
xref: RelationshipXref imex IM-15332-12472 imex-primary
xref: UnificationXref mint MINT-2195970
evidence: Evidence 7c100bba-ad72-4822-9b9e-df4aad89c24a IM-15332-12472 430549 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: -0.0542734280474321
comment: author-confidence:reliability score: 0.983
comment: comment:mint
data source: intact
participant: Protein uniprotkb P25441 identity 1529029541679
participant: Protein uniprotkb P22276 identity 1529029541678

rco1-htb2-2
type: MolecularInteraction
xref: RelationshipXref intact EBI-7515254 identity
xref: RelationshipXref imex IM-15332-5969 imex-primary
xref: UnificationXref mint MINT-2195375
evidence: Evidence cc3ad2e9-c658-43b3-9722-178c824619d1 IM-15332-5969 430417 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.409
comment: comment:mint
comment: author-confidence:z-score: 1.1316898755917
data source: intact
participant: Protein uniprotkb P02294 identity 1529029541613
participant: rco1_yeast

RelationshipXref imex IM-15332-5987 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5987
db: imex

ExperimentalForm b4920b5e-4a21-4ca0-9786-be2312585800
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7521076 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7521076
db: intact

RelationshipXref interpro IPR004790
type: RelationshipXref
id: IPR004790
db: interpro

ExperimentalForm a7c52ace-aaf9-49b4-902a-448fac71bb37
type: ExperimentalForm
experimental feature: ModificationFeature fd292c5a-eb02-4089-a788-c901c175fd6d 433808
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref interpro IPR001878
type: RelationshipXref
id: IPR001878
db: interpro

RelationshipXref mint P22139
type: RelationshipXref
id: P22139
db: mint

rpn1-rpn10-5
type: MolecularInteraction
xref: UnificationXref mint MINT-2210174
xref: RelationshipXref intact EBI-7541701 identity
xref: RelationshipXref imex IM-15332-9623 imex-primary
evidence: Evidence 1e149f6b-35e4-48ce-a9e2-26e93bba0473 IM-15332-9623 433693 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 9.10027180285288
comment: comment:mint
comment: author-confidence:reliability score: 0.934
data source: intact
participant: Protein uniprotkb P38764 identity 1529029543251
participant: Protein uniprotkb P38886 identity 1529029543250

RelationshipXref dip DIP-7376N
type: RelationshipXref
id: DIP-7376N
db: database of interacting proteins

ExperimentalForm 8e8b63ee-bafa-4951-9a29-4540d340dd50
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpn1-rpn8-4
type: MolecularInteraction
xref: RelationshipXref intact EBI-7543016 identity
xref: UnificationXref mint MINT-2210876
xref: RelationshipXref imex IM-15332-2372 imex-primary
evidence: Evidence 539a672a-aa3d-4e0e-949a-18c8d6e17e56 IM-15332-2372 433849 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:z-score: 2.77987973140138
comment: author-confidence:reliability score: 0.99
data source: intact
participant: rpn8_yeast
participant: Protein uniprotkb P38764 identity 1529029543329

ExperimentalForm 86b1a515-0f24-452e-a571-2fcd6decbb7c
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref mint MINT-2201786
type: UnificationXref
id: MINT-2201786
db: mint

RelationshipXref uniprotkb D6W1D5 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6W1D5
db: uniprot knowledgebase

ExperimentalForm 209da41d-52a7-4f03-bbb3-ba15187a31c1
type: ExperimentalForm
experimental feature: ModificationFeature 1a3fa035-f60b-42a3-91bf-465d7a357940 432524
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm d8a4b1fd-1aae-4eb6-8c28-a14d4adbd29f
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpc7_yeast
type: Protein
evidence: Evidence 68f356f0-ae3b-40b3-9b44-bcb5155effae p 432914
entity reference: P17890
name: DNA-directed RNA polymerase III subunit RPC7
comment: psi-mi participant
data source: intact

csk21_yeast
type: ProteinReference
sequence: MKCRVWSEARVYTNINKQRTEEYWDYENTVIDWSTNTKDYEIENKVGRGKYSEVFQGVKLDSKVKIVIKMLKPVKKKKIKREIKILTDLSNEKVPPTTLPFQKDQYYTNQKEDVLKFIRPYIFDQPHNGHANIIHLFDIIKDPISKTPALVFEYVDNVDFRILYPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLGTSDFEKYLLKYEITLPREFYDMDQYIRKPWHRFINDGNKHLSGNDEIIDLIDNLLRYDHQERLTAKEAMGHPWFAPIREQIEK
xref: RelationshipXref uniprotkb D6VVP7 secondary-ac
xref: RelationshipXref interpro IPR008271
xref: RelationshipXref go GO 0005524
xref: RelationshipXref rcsb pdb 4LFI
xref: RelationshipXref go GO 0018107
xref: RelationshipXref go GO 0018105
xref: RelationshipXref go GO 0005654
xref: RelationshipXref dip DIP-48N
xref: RelationshipXref rcsb pdb 4JR7
xref: RelationshipXref intact EBI-9533 identity
xref: RelationshipXref mint P15790
xref: RelationshipXref go GO 0042802
xref: RelationshipXref refseq NP 012229 1
xref: RelationshipXref go GO 0031167
xref: RelationshipXref rcsb pdb 4JQE
xref: RelationshipXref interpro IPR000719
xref: RelationshipXref go GO 0005956
xref: RelationshipXref interpro IPR017441
xref: RelationshipXref go GO 0007535
xref: RelationshipXref go GO 0006468
xref: RelationshipXref go GO 0034456
xref: RelationshipXref go GO 0004674
xref: RelationshipXref go GO 0006974
xref: RelationshipXref go GO 0006359
xref: RelationshipXref rcsb pdb 4MWH
xref: RelationshipXref go GO 0006356
xref: RelationshipXref rcsb pdb 4FI1
xref: RelationshipXref sgd S000001297
xref: RelationshipXref interpro IPR011009
xref: UnificationXref uniprot knowledgebase P15790
organism: http://identifiers.org/taxonomy/559292
name: CKA1
name: YIL035C
name: Casein kinase II subunit alpha

UnificationXref mint MINT-2195718
type: UnificationXref
id: MINT-2195718
db: mint

RelationshipXref imex IM-15332-12495 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12495
db: imex

rpc7_yeast
type: Protein
evidence: Evidence 1444d850-0e03-4a90-b617-4898044822e1 p 432911
entity reference: P17890
name: DNA-directed RNA polymerase III subunit RPC7
comment: psi-mi participant
data source: intact

rpc7_yeast
type: Protein
evidence: Evidence d2f0aa27-5039-4095-bc0d-7e7555844637 p 432906
entity reference: P17890
name: DNA-directed RNA polymerase III subunit RPC7
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7515456 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7515456
db: intact

rpc7_yeast
type: Protein
evidence: Evidence 2e28721e-f314-4652-be22-219bdf4ba324 p 432902
entity reference: P17890
name: DNA-directed RNA polymerase III subunit RPC7
comment: psi-mi participant
data source: intact

rpc7_yeast
type: Protein
evidence: Evidence 984ba4ec-0178-40c2-ae12-6ccb743f6cc0 p 432899
entity reference: P17890
name: DNA-directed RNA polymerase III subunit RPC7
comment: psi-mi participant
data source: intact

RelationshipXref interpro IPR021133
type: RelationshipXref
id: IPR021133
db: interpro

rpc7_yeast
type: Protein
evidence: Evidence 99e4752c-a813-4573-8c23-89e13477cdd8 p 432895
entity reference: P17890
name: DNA-directed RNA polymerase III subunit RPC7
comment: psi-mi participant
data source: intact

ExperimentalForm 5c7add89-cb17-4f40-8b6c-496dfed2e493
type: ExperimentalForm
experimental feature: ModificationFeature d7e35ae1-6965-4b35-abd9-6119eeaf6898 433216
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref interpro IPR001895
type: RelationshipXref
id: IPR001895
db: interpro

RelationshipXref interpro IPR024084
type: RelationshipXref
id: IPR024084
db: interpro

RelationshipXref go GO 0005788
type: RelationshipXref
id: GO:0005788
db: gene ontology

RelationshipXref refseq NP 015516 1
type: RelationshipXref
id: NP_015516.1
db: refseq

UnificationXref mint MINT-2205033
type: UnificationXref
id: MINT-2205033
db: mint

ExperimentalForm 1f3a0f10-6fd2-4871-9b28-f38e3ce093d3
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpc7_yeast
type: Protein
evidence: Evidence b2cf6594-0209-4aa8-aa8d-1d18978ea74a p 432891
entity reference: P17890
name: DNA-directed RNA polymerase III subunit RPC7
comment: psi-mi participant
data source: intact

rpc7_yeast
type: Protein
evidence: Evidence daac8730-b3be-4adb-b3ee-5fd1c53dfe80 p 432886
entity reference: P17890
name: DNA-directed RNA polymerase III subunit RPC7
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-12045 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12045
db: imex

rpc7_yeast
type: Protein
evidence: Evidence f5b07d07-768c-4fb0-bece-295f676ae637 p 432882
entity reference: P17890
name: DNA-directed RNA polymerase III subunit RPC7
comment: psi-mi participant
data source: intact

Evidence 41f87431-e20f-4d36-9254-b8c54355c389 IM-15332-2744 431865 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref sgd S000002837
type: RelationshipXref
id: S000002837
db: sgd

RelationshipXref sgd S000002835
type: RelationshipXref
id: S000002835
db: sgd

ExperimentalForm 1b0dd413-1764-486f-8b87-ff06a2d45265
type: ExperimentalForm
experimental feature: ModificationFeature f6934b48-d038-4014-892b-ee5a259ef30a 432867
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

Evidence 7003a5db-66e0-4251-9417-a6e330a853c9 IM-15332-11248 432093 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref intact EBI-15206 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-15206
db: intact

rpn1-rpt5-4
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-10864 imex-primary
xref: RelationshipXref intact EBI-7542232 identity
xref: UnificationXref mint MINT-2210372
evidence: Evidence f8845721-260f-4210-a027-ff35f85a7135 IM-15332-10864 433737 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 3.77107955681328
comment: author-confidence:reliability score: 0.984
comment: comment:mint
data source: intact
participant: prs6a_yeast
participant: Protein uniprotkb P38764 identity 1529029543273

RelationshipXref imex IM-15332-8818 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-8818
db: imex

RelationshipXref interpro IPR037316
type: RelationshipXref
id: IPR037316
db: interpro

RelationshipXref rcsb pdb 4RUR
type: RelationshipXref
id: 4RUR
db: protein data bank

ExperimentalForm c4ed83f5-0838-44d1-94d6-8a4aa2d07082
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref dip DIP-3993N
type: RelationshipXref
id: DIP-3993N
db: database of interacting proteins

rpc7_yeast
type: Protein
evidence: Evidence c7730175-fc02-4104-9eb4-3afbe853ba64 p 432866
entity reference: P17890
name: DNA-directed RNA polymerase III subunit RPC7
comment: psi-mi participant
data source: intact

ExperimentalForm 5c219ac0-22e4-4053-9248-f90f9ab063f2
type: ExperimentalForm
experimental feature: ModificationFeature faf0cad5-4fce-46bc-bf8d-586a623bf1ee 433011
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpc7_yeast
type: Protein
evidence: Evidence 458a84f5-c9ae-4e57-9383-4e89cf6c89ba p 432862
entity reference: P17890
name: DNA-directed RNA polymerase III subunit RPC7
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7518876 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7518876
db: intact

UnificationXref mint MINT-2209328
type: UnificationXref
id: MINT-2209328
db: mint

RelationshipXref sgd S000002826
type: RelationshipXref
id: S000002826
db: sgd

RelationshipXref intact EBI-3913 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-3913
db: intact

RelationshipXref rcsb pdb 3NZW
type: RelationshipXref
id: 3NZW
db: protein data bank

ExperimentalForm f540afb1-7434-4604-b040-ac5741671b9c
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7517580 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7517580
db: intact

ExperimentalForm 41b64b31-03b6-4bbf-986e-3a185dbfd8f1
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref mint MINT-2205015
type: UnificationXref
id: MINT-2205015
db: mint

UnificationXref uniprot knowledgebase Q04067
type: UnificationXref
id: Q04067
db: uniprot knowledgebase

RelationshipXref rcsb pdb 3NZJ
type: RelationshipXref
id: 3NZJ
db: protein data bank

RelationshipXref imex IM-15332-1575 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1575
db: imex

rpc9_yeast
type: Protein
evidence: Evidence 3c4a103a-c646-4820-9d8f-542b23daf396 p 433038
entity reference: rpc9_yeast
name: DNA-directed RNA polymerase III subunit RPC9
comment: psi-mi participant
data source: intact

RelationshipXref mint P22579
type: RelationshipXref
id: P22579
db: mint

ExperimentalForm a383fe24-80b1-44cc-b603-079d4859329f
type: ExperimentalForm
experimental feature: ModificationFeature beb7a863-47cf-4458-a2b3-dbe00452dfac 433740
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 83a3b5ec-8751-4f19-bef3-81d12d2056ce
type: ExperimentalForm
experimental feature: ModificationFeature 7af4fbc5-3174-4094-b0ce-b268b98b34e4 433744
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpab1_yeast
type: Protein
evidence: Evidence c6b09305-064f-43bf-bf07-095030192a9e p 432964
entity reference: rpab1_yeast
name: DNA-directed RNA polymerases I, II, and III subunit RPABC1
comment: psi-mi participant
data source: intact

RelationshipXref interpro IPR024055
type: RelationshipXref
id: IPR024055
db: interpro

RelationshipXref interpro IPR024054
type: RelationshipXref
id: IPR024054
db: interpro

RelationshipXref uniprotkb D6VUW4 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VUW4
db: uniprot knowledgebase

ExperimentalForm a227918b-0504-43d1-9792-7ee6b4d0efd3
type: ExperimentalForm
experimental feature: ModificationFeature 124c3bb0-1d88-4a9d-b1b7-9e92f96bfec6 432176
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7538806 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7538806
db: intact

RelationshipXref mint P38779
type: RelationshipXref
id: P38779
db: mint

rpc9_yeast
type: Protein
evidence: Evidence 52ef9d3b-f905-4f1b-9c61-d96615a15047 p 433026
entity reference: rpc9_yeast
name: DNA-directed RNA polymerase III subunit RPC9
comment: psi-mi participant
data source: intact

RelationshipXref sgd S000002802
type: RelationshipXref
id: S000002802
db: sgd

ExperimentalForm 16a40824-8950-48ba-8d17-93f51cf2615a
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

mck1_yeast
type: Protein
evidence: Evidence c3bc22e4-68dc-4603-bfea-dc5333745c0e p 430966
entity reference: P21965
name: Protein kinase MCK1
comment: psi-mi participant
data source: intact

rpc19-rpa190
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-12058 imex-primary
xref: UnificationXref mint MINT-2205745
xref: RelationshipXref intact EBI-7532483 identity
evidence: Evidence 367e7a23-f12a-4213-9366-26d9dcb3de77 IM-15332-12058 432709 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 0.0203008758729083
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P10964 identity 1529029542759
participant: rpac2_yeast

RelationshipXref intact EBI-7520962 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7520962
db: intact

ExperimentalForm 9283eb60-8d41-494e-868f-e70c6ab0f502
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref refseq NP 012950 3
type: RelationshipXref
id: NP_012950.3
db: refseq

Evidence 6301456f-cdf8-43d3-a018-d2266944b8a5 IM-15332-8411 431205 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpn1-rpt1-21
type: MolecularInteraction
xref: RelationshipXref intact EBI-7543483 identity
xref: UnificationXref mint MINT-2211038
xref: RelationshipXref imex IM-15332-8826 imex-primary
evidence: Evidence 94a7ee33-81bf-4da2-b5f4-4c0bec5bdf18 IM-15332-8826 433885 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.93
comment: comment:homomint
comment: author-confidence:z-score: 0.548797887460183
comment: comment:mint
data source: intact
participant: prs7_yeast
participant: Protein uniprotkb P38764 identity 1529029543346

RelationshipXref imex IM-15332-412 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-412
db: imex

RelationshipXref mint P38764
type: RelationshipXref
id: P38764
db: mint

rfa2_yeast
type: Protein
evidence: Evidence 84f5ebc4-65c9-408b-9dd7-084c782efc72 p 430710
entity reference: P26754
name: Replication factor A protein 2
comment: psi-mi participant
data source: intact

RelationshipXref interpro IPR019585
type: RelationshipXref
id: IPR019585
db: interpro

RelationshipXref imex IM-15332-6369 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-6369
db: imex

rim11_yeast
type: Protein
evidence: Evidence 8e82d2cf-a5ae-4073-a2b5-b40c6b829056 p 431087
entity reference: P38615
name: Serine/threonine-protein kinase RIM11/MSD1
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-2763 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-2763
db: imex

rpa43-rpa190
type: MolecularInteraction
xref: UnificationXref mint MINT-2201786
xref: RelationshipXref intact EBI-7523827 identity
xref: RelationshipXref imex IM-15332-10438 imex-primary
evidence: Evidence 005ed3cb-2f65-4cab-97a2-31c9b72b285f IM-15332-10438 431841 430156
interaction type: physical association
comment: author-confidence:z-score: 2.61097780663138
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P10964 identity 1529029542324
participant: rpa43_yeast

RelationshipXref intact EBI-4898 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-4898
db: intact

RelationshipXref go GO 0070893
type: RelationshipXref
id: GO:0070893
db: gene ontology

ExperimentalForm ac973644-a7b3-4262-94eb-0fd2e9258406
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref rcsb pdb 5VKO
type: RelationshipXref
id: 5VKO
db: protein data bank

RelationshipXref rcsb pdb 5VKL
type: RelationshipXref
id: 5VKL
db: protein data bank

RelationshipXref intact EBI-8958 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-8958
db: intact

rl12_yeast
type: Protein
evidence: Evidence 2327aaeb-e210-4132-a04c-d152a02f48ee p 433567
entity reference: P17079
name: 60S ribosomal protein L12
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-4406 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-4406
db: imex

RelationshipXref intact EBI-15741 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-15741
db: intact

ExperimentalForm 366ceb3b-38e5-4ef2-a85c-573c720c625c
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref uniprot knowledgebase P39708
type: UnificationXref
id: P39708
db: uniprot knowledgebase

rpb10-rpa135-3
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-5174 imex-primary
xref: RelationshipXref intact EBI-7524435 identity
xref: UnificationXref mint MINT-2202237
evidence: Evidence 05923edf-40ba-410b-a492-abd992b0875e IM-15332-5174 431941 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.932
comment: author-confidence:z-score: 0.889624750817536
comment: comment:mint
data source: intact
participant: rpab5_yeast
participant: Protein uniprotkb P22138 identity 1529029542375

RelationshipXref uniprotkb D6VXR8 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VXR8
db: uniprot knowledgebase

ExperimentalForm 0367d25f-8165-43b8-ba4e-b703bd3028c5
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 66556684-ee04-41b3-9066-5b118aab630b
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref go GO 0070880
type: RelationshipXref
id: GO:0070880
db: gene ontology

RelationshipXref go GO 0006396
type: RelationshipXref
id: GO:0006396
db: gene ontology

RelationshipXref intact EBI-7522138 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7522138
db: intact

RelationshipXref go GO 0006273
type: RelationshipXref
id: GO:0006273
db: gene ontology

UnificationXref uniprot knowledgebase P22147
type: UnificationXref
id: P22147
db: uniprot knowledgebase

rfa1_yeast
type: Protein
evidence: Evidence 92531dd7-7564-4a18-95b2-fde74f7fb908 p 430866
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

rfa1_yeast
type: Protein
evidence: Evidence 4a29390c-2486-4292-82c8-601cd409139f p 430862
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-9642 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-9642
db: intact

eif3a_yeast
type: Protein
evidence: Evidence 23865061-65a6-4107-aba4-7fb94ca9c3bb p 433391
entity reference: P38249
name: Eukaryotic translation initiation factor 3 subunit A
comment: psi-mi participant
data source: intact

rna14_yeast
type: ProteinReference
sequence: MSSSTTPDLLYPSADKVAEPSDNIHGDELRLRERIKDNPTNILSYFQLIQYLETQESYAKVREVYEQFHNTFPFYSPAWTLQLKGELARDEFETVEKILAQCLSGKLENNDLSLWSTYLDYIRRKNNLITGGQEARAVIVKAFQLVMQKCAIFEPKSSSFWNEYLNFLEQWKPFNKWEEQQRIDMLREFYKKMLCVPFDNLEKMWNRYTQWEQEINSLTARKFIGELSAEYMKARSLYQEWLNVTNGLKRASPINLRTANKKNIPQPGTSDSNIQQLQIWLNWIKWERENKLMLSEDMLSQRISYVYKQGIQYMIFSAEMWYDYSMYISENSDRQNILYTALLANPDSPSLTFKLSECYELDNDSESVSNCFDKCTQTLLSQYKKIASDVNSGEDNNTEYEQELLYKQREKLTFVFCVYMNTMKRISGLSAARTVFGKCRKLKRILTHDVYVENAYLEFQNQNDYKTAFKVLELGLKYFQNDGVYINKYLDFLIFLNKDSQIKTLFETSVEKVQDLTQLKEIYKKMISYESKFGNLNNVYSLEKRFFERFPQENLIEVFTSRYQIQNSNLIKKLELTYMYNEEEDSYFSSGNGDGHHGSYNMSSSDRKRLMEETGNNGNFSNKKFKRDSELPTEVLDLLSVIPKRQYFNTNLLDAQKLVNFLNDQVEIPTVESTKSG
xref: UnificationXref uniprot knowledgebase P25298
xref: RelationshipXref go GO 0005634
xref: RelationshipXref go GO 0046982
xref: RelationshipXref refseq NP 013777 1
xref: RelationshipXref go GO 0098789
xref: RelationshipXref rcsb pdb 2L9B
xref: RelationshipXref interpro IPR008847
xref: RelationshipXref interpro IPR003107
xref: RelationshipXref dip DIP-1488N
xref: RelationshipXref uniprotkb D6VZN5 secondary-ac
xref: RelationshipXref go GO 0072423
xref: RelationshipXref go GO 0005739
xref: RelationshipXref go GO 0005849
xref: RelationshipXref mint P25298
xref: RelationshipXref reactome R-SCE-77595
xref: RelationshipXref go GO 0005829
xref: RelationshipXref interpro IPR011990
xref: RelationshipXref intact EBI-15632 identity
xref: RelationshipXref sgd S000004665
xref: RelationshipXref go GO 0006378
xref: RelationshipXref go GO 0003729
organism: http://identifiers.org/taxonomy/559292
name: mRNA 3'-end-processing protein RNA14
name: RNA14
name: YMR061W
name: YM9796.14

RelationshipXref intact EBI-7515071 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7515071
db: intact

nap1_yeast
type: ProteinReference
sequence: MSDPIRTKPKSSMQIDNAPTPHNTPASVLNPSYLKNGNPVRAQAQEQDDKIGTINEEDILANQPLLLQSIQDRLGSLVGQDSGYVGGLPKNVKEKLLSLKTLQSELFEVEKEFQVEMFELENKFLQKYKPIWEQRSRIISGQEQPKPEQIAKGQEIVESLNETELLVDEEEKAQNDSEEEQVKGIPSFWLTALENLPIVCDTITDRDAEVLEYLQDIGLEYLTDGRPGFKLLFRFDSSANPFFTNDILCKTYFYQKELGYSGDFIYDHAEGCEISWKDNAHNVTVDLEMRKQRNKTTKQVRTIEKITPIESFFNFFDPPKIQNEDQDEELEEDLEERLALDYSIGEQLKDKLIPRAVDWFTGAALEFEFEEDEEEADEDEDEEEDDDHGLEDDDGESAEEQDDFAGRPEQAPECKQS
xref: RelationshipXref mint P25293
xref: RelationshipXref intact EBI-11850 identity
xref: RelationshipXref go GO 0042802
xref: RelationshipXref interpro IPR037231
xref: RelationshipXref go GO 0005935
xref: RelationshipXref rcsb pdb 2AYU
xref: RelationshipXref uniprotkb P87196 secondary-ac
xref: RelationshipXref interpro IPR002164
xref: RelationshipXref dip DIP-1380N
xref: RelationshipXref uniprotkb D6VXA9 secondary-ac
xref: RelationshipXref go GO 0006337
xref: RelationshipXref refseq NP 012974 1
xref: RelationshipXref go GO 0006334
xref: RelationshipXref go GO 0008047
xref: RelationshipXref go GO 0043085
xref: RelationshipXref sgd S000001756
xref: UnificationXref uniprot knowledgebase P25293
xref: RelationshipXref go GO 0006606
xref: RelationshipXref rcsb pdb 5G2E
xref: RelationshipXref go GO 0042393
xref: RelationshipXref go GO 0030332
xref: RelationshipXref go GO 0007117
xref: RelationshipXref go GO 0003677
xref: RelationshipXref go GO 0005634
xref: RelationshipXref go GO 0005737
xref: RelationshipXref rcsb pdb 2Z2R
xref: RelationshipXref go GO 2000617
xref: RelationshipXref go GO 0031116
xref: RelationshipXref go GO 0032968
organism: http://identifiers.org/taxonomy/559292
name: Nucleosome assembly protein
name: YKR048C
name: NAP1

RelationshipXref refseq NP 683716 1
type: RelationshipXref
id: NP_683716.1
db: refseq

RelationshipXref imex IM-15332-11253 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-11253
db: imex

ExperimentalForm 91aa45b6-b3b6-496b-b32d-97d0a5d570bd
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref go GO 0006386
type: RelationshipXref
id: GO:0006386
db: gene ontology

RelationshipXref go GO 0006384
type: RelationshipXref
id: GO:0006384
db: gene ontology

RelationshipXref go GO 0006383
type: RelationshipXref
id: GO:0006383
db: gene ontology

UnificationXref uniprot knowledgebase P22139
type: UnificationXref
id: P22139
db: uniprot knowledgebase

UnificationXref uniprot knowledgebase P22138
type: UnificationXref
id: P22138
db: uniprot knowledgebase

rfa1_yeast
type: Protein
evidence: Evidence 9f485f4d-069a-4808-9044-60d9a90ba999 p 430848
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 3O5H
type: RelationshipXref
id: 3O5H
db: protein data bank

rfa1_yeast
type: Protein
evidence: Evidence a57b59cf-919f-4868-b1b3-dd14b6a21f59 p 430844
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

RelationshipXref refseq NP 012243 3
type: RelationshipXref
id: NP_012243.3
db: refseq

rfa1_yeast
type: Protein
evidence: Evidence 7e955ff8-af81-431e-a617-9cc76029c89a p 430840
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

rfa1_yeast
type: Protein
evidence: Evidence 3e83dd0c-88c9-422a-8dc4-28d5df476d14 p 430836
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

RelationshipXref mint P51862
type: RelationshipXref
id: P51862
db: mint

RelationshipXref uniprotkb P89891 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: P89891
db: uniprot knowledgebase

UnificationXref uniprot knowledgebase Q12159
type: UnificationXref
id: Q12159
db: uniprot knowledgebase

RelationshipXref rcsb pdb 2JYN
type: RelationshipXref
id: 2JYN
db: protein data bank

rpc17-ret1
type: MolecularInteraction
xref: UnificationXref mint MINT-2205295
xref: RelationshipXref intact EBI-7531718 identity
xref: RelationshipXref imex IM-15332-1219 imex-primary
evidence: Evidence ce53246f-5f1d-4f48-9108-8adfea3d2ae4 IM-15332-1219 432609 430156
interaction type: physical association
comment: author-confidence:z-score: 4.45605581964469
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P22276 identity 1529029542708
participant: rpc9_yeast

RelationshipXref go GO 0006378
type: RelationshipXref
id: GO:0006378
db: gene ontology

RelationshipXref rcsb pdb 3O58
type: RelationshipXref
id: 3O58
db: protein data bank

RelationshipXref sgd S000000065
type: RelationshipXref
id: S000000065
db: sgd

RelationshipXref go GO 0006370
type: RelationshipXref
id: GO:0006370
db: gene ontology

ExperimentalForm 3e083356-5f3c-4b4f-9847-2cd0586b9f4a
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rfa1_yeast
type: Protein
evidence: Evidence fc6ce49b-be67-424a-bbf9-4bb253cf99b8 p 430832
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

rfa1_yeast
type: Protein
evidence: Evidence 28743856-b596-431b-8037-718e42129f0a p 430828
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

rfa1_yeast
type: Protein
evidence: Evidence 9fc0d795-e33f-485b-8fda-ddb5e64c1ab0 p 430824
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

rfa1_yeast
type: Protein
evidence: Evidence cb63bd00-1ef2-4ee0-ac10-ae499b1d69c8 p 430820
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

rfc1-rfc3-5
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-10428 imex-primary
xref: RelationshipXref intact EBI-7517853 identity
xref: UnificationXref mint MINT-2197664
evidence: Evidence 1edfa5e9-f131-41a4-a016-1ba46c1085ad IM-15332-10428 430925 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.989
comment: author-confidence:z-score: 9.34909362936676
comment: comment:mint
data source: intact
participant: Protein uniprotkb P38630 identity 1529029541867
participant: Protein uniprotkb P38629 identity 1529029541866

RelationshipXref uniprotkb P87196 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: P87196
db: uniprot knowledgebase

RelationshipXref intact EBI-34978 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-34978
db: intact

RelationshipXref go GO 0006369
type: RelationshipXref
id: GO:0006369
db: gene ontology

RelationshipXref go GO 0006368
type: RelationshipXref
id: GO:0006368
db: gene ontology

RelationshipXref go GO 0006367
type: RelationshipXref
id: GO:0006367
db: gene ontology

RelationshipXref sgd S000000058
type: RelationshipXref
id: S000000058
db: sgd

RelationshipXref rcsb pdb 3NS6
type: RelationshipXref
id: 3NS6
db: protein data bank

RelationshipXref go GO 0006364
type: RelationshipXref
id: GO:0006364
db: gene ontology

RelationshipXref go GO 0006363
type: RelationshipXref
id: GO:0006363
db: gene ontology

RelationshipXref go GO 0006362
type: RelationshipXref
id: GO:0006362
db: gene ontology

RelationshipXref go GO 0006360
type: RelationshipXref
id: GO:0006360
db: gene ontology

Evidence 97a38630-1f2d-4853-bfd0-9323f057ce87 IM-15332-12884 432737 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpb9-rpb4
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-2751 imex-primary
xref: RelationshipXref intact EBI-7529977 identity
xref: UnificationXref mint MINT-2204382
evidence: Evidence ec6b4103-c490-4688-83a8-a5951b0cb570 IM-15332-2751 432417 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.989
comment: author-confidence:z-score: 8.89974299994146
comment: comment:mint
data source: intact
participant: Protein uniprotkb P27999 identity 1529029542612
participant: Protein uniprotkb P20433 identity 1529029542613

RelationshipXref mint Q12527
type: RelationshipXref
id: Q12527
db: mint

ExperimentalForm 52f3665a-5815-439c-a407-1fe4f5f79a89
type: ExperimentalForm
experimental feature: ModificationFeature 3a854b9d-6b05-4c0d-8004-d1ccda8d33e9 433843
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

bud2_yeast
type: Protein
evidence: Evidence 6f223dae-fe16-4f9c-bf58-cda846c506f0 p 432818
entity reference: bud2_yeast
name: Inhibitory regulator protein BUD2/CLA2
comment: psi-mi participant
data source: intact

rpg1-nip1-3
type: MolecularInteraction
xref: UnificationXref mint MINT-2208896
xref: RelationshipXref imex IM-15332-10861 imex-primary
xref: RelationshipXref intact EBI-7538806 identity
evidence: Evidence 8b08c763-5e21-4847-9c38-c6a31c613de7 IM-15332-10861 433409 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 6.21083971650559
comment: comment:mint
comment: author-confidence:reliability score: 0.968
data source: intact
participant: Protein uniprotkb P32497 identity 1529029543109
participant: Protein uniprotkb P38249 identity 1529029543108

RelationshipXref go GO 0070847
type: RelationshipXref
id: GO:0070847
db: gene ontology

rir3_yeast
type: ProteinReference
sequence: MYVIKRDGRKEPVQFDKITSRITRLSYGLDPNRIDAVKVTQRIISGVYSGVTTVELDNLAAETCAYMTTVHPDYATLAARIAISNLHKQTTKQFSKVIEDLHDWINPATGKHAPMISDEIYNIVMENKDTLNSAIVYDRDFQYTYFGFKTLERSYLLRLNGEVAERPQHLVMRVALGIHGSDIESVLKTYNLMSLRYFTHASPTLFNAGTPHPQMSSCFLIAMKDDSIEGIYDTLKECAMISKTAGGVGLHINNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALFLEPWHADIFDFVDIRKTHGKEEIRARDLFPALWIPDLFMKRVQEDGPWTLFSPSAAPGLDDVWGDEFEELYTRYEREGRGKTIKAQKLWYAILQAQTETGTPFMVYKDACNRKTNQQNLGTIKSSNLCCEIVEYSSPDETAVCNLASIALPAFVEVSEDGKTASYNFERLHEIAKVITHNLNRVIDRNYYPVPEARNSNMKHRPIALGVQGLADTYMMLRLPFESEEAQTLNKQIFETIYHATLEASCELAQKEGKYSTFEGSPASKGILQFDMWNAKPFGMWDWETLRKDIVKHGLRNSLTMAPMPTASTSQILGYNECFEPVTSNMYSRRVLSGEFQVVNPYLLRDLVDLGIWDDSMKQYLITQNGSIQGLPNVPQELKELYKTVWEISQKTIINMAADRAIYIDQSHSLNLFLQAPSMGKITSMHFYGWKKGLKTGMYYLRTQAASAAIQFTIDQEVADQAATHIASVSELDRPVYVPKGTKFSEQKAASALTESSDNEKDASPVPSEQSSVSSAMSNVKLEDSVAPAVPTETIKEDSDEKKCDIYNEKVIACTAPTPEACESCSG
xref: RelationshipXref interpro IPR000788
xref: RelationshipXref go GO 0006260
xref: RelationshipXref interpro IPR005144
xref: RelationshipXref go GO 0005971
xref: RelationshipXref refseq NP 012198 3
xref: RelationshipXref interpro IPR013509
xref: RelationshipXref sgd S000001328
xref: RelationshipXref dip DIP-2563N
xref: RelationshipXref interpro IPR008926
xref: RelationshipXref go GO 0009263
xref: RelationshipXref interpro IPR013346
xref: RelationshipXref go GO 0005737
xref: RelationshipXref mint P21672
xref: RelationshipXref go GO 0005524
xref: RelationshipXref go GO 0004748
xref: RelationshipXref uniprotkb D6VVL8 secondary-ac
xref: RelationshipXref intact EBI-15246 identity
xref: UnificationXref uniprot knowledgebase P21672
organism: http://identifiers.org/taxonomy/559292
name: DIN1
name: Ribonucleotide reductase R1 subunit 2
name: Ribonucleotide reductase large subunit 2
name: YIL066C
name: Ribonucleoside-diphosphate reductase large chain 2
name: RNR3
name: Ribonucleotide reductase DNA damage-inducible regulatory subunit 2

UnificationXref uniprot knowledgebase P09938
type: UnificationXref
id: P09938
db: uniprot knowledgebase

RelationshipXref go GO 0070842
type: RelationshipXref
id: GO:0070842
db: gene ontology

RelationshipXref go GO 0006357
type: RelationshipXref
id: GO:0006357
db: gene ontology

RelationshipXref go GO 0006356
type: RelationshipXref
id: GO:0006356
db: gene ontology

RelationshipXref intact EBI-7540079 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7540079
db: intact

RelationshipXref go GO 0006354
type: RelationshipXref
id: GO:0006354
db: gene ontology

RelationshipXref go GO 0006353
type: RelationshipXref
id: GO:0006353
db: gene ontology

RelationshipXref go GO 0006351
type: RelationshipXref
id: GO:0006351
db: gene ontology

RelationshipXref sgd S000000041
type: RelationshipXref
id: S000000041
db: sgd

rnr4-rnr2-8
type: MolecularInteraction
xref: UnificationXref mint MINT-2200130
xref: RelationshipXref imex IM-15332-12049 imex-primary
xref: RelationshipXref intact EBI-7521262 identity
evidence: Evidence 48f6adfb-adf6-4ada-a2e2-74000622db6e IM-15332-12049 431473 430156
interaction type: physical association
comment: author-confidence:z-score: 2.22170276776604
comment: author-confidence:reliability score: 0.877
comment: comment:mint
data source: intact
participant: Protein uniprotkb P49723 identity 1529029542140
participant: rir2_yeast

UnificationXref uniprot knowledgebase P21672
type: UnificationXref
id: P21672
db: uniprot knowledgebase

ExperimentalForm f801d825-0961-42e0-ad4c-7a601bc77f08
type: ExperimentalForm
experimental feature: ModificationFeature ed6fa630-3b76-499b-9e88-7cec7efc469d 431459
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

Evidence b344060b-602e-4d3b-bfb4-4bfecc447f8c IM-15332-3598 433765 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref mint Q12510
type: RelationshipXref
id: Q12510
db: mint

rpb10-rpo26-1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-5983 imex-primary
xref: UnificationXref mint MINT-2202993
xref: RelationshipXref intact EBI-7525716 identity
evidence: Evidence 94e4ae1a-fa67-402b-9ffb-fd69191523dd IM-15332-5983 432109 430156
interaction type: physical association
comment: author-confidence:z-score: 0.326563187445805
comment: comment:homomint
comment: author-confidence:reliability score: 0.579
comment: comment:mint
data source: intact
participant: rpab2_yeast
participant: rpab5_yeast

ExperimentalForm e8dcabbc-d473-425f-8a49-f0c3c0bac39f
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

Evidence ff82c70e-1d8b-4c8f-9c9e-638429f9d3aa IM-15332-10847 430805 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref go GO 0006342
type: RelationshipXref
id: GO:0006342
db: gene ontology

rpc40-rpa190-1
type: MolecularInteraction
xref: RelationshipXref intact EBI-7534834 identity
xref: RelationshipXref imex IM-15332-7646 imex-primary
xref: UnificationXref mint MINT-2207006
evidence: Evidence c1d32888-4bd9-4c1d-ab9b-e3c3efb8aca4 IM-15332-7646 432989 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.97
comment: author-confidence:z-score: 2.70267504119116
data source: intact
participant: Protein uniprotkb P10964 identity 1529029542898
participant: Protein uniprotkb P07703 identity 1529029542899

UnificationXref uniprot knowledgebase P38304
type: UnificationXref
id: P38304
db: uniprot knowledgebase

UnificationXref uniprot knowledgebase P46995
type: UnificationXref
id: P46995
db: uniprot knowledgebase

RelationshipXref interpro IPR003307
type: RelationshipXref
id: IPR003307
db: interpro

rpd3-sin3-2
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-4792 imex-primary
xref: UnificationXref mint MINT-2208428
xref: RelationshipXref intact EBI-7538033 identity
evidence: Evidence bdf729c9-7a10-4160-bc26-94670229c512 IM-15332-4792 433305 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 2.6685776625032
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: rpd3_yeast
participant: Protein uniprotkb P22579 identity 1529029543057

RelationshipXref interpro IPR011993
type: RelationshipXref
id: IPR011993
db: interpro

ExperimentalForm d41d8f63-6332-4e81-8844-4bfc536248af
type: ExperimentalForm
experimental feature: ModificationFeature 84948907-2c00-4dfb-9949-ed4aed80cc43 430671
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref interpro IPR011990
type: RelationshipXref
id: IPR011990
db: interpro

ret2-sec26-5
type: MolecularInteraction
xref: RelationshipXref intact EBI-7516086 identity
xref: UnificationXref mint MINT-2196186
xref: RelationshipXref imex IM-15332-5579 imex-primary
evidence: Evidence 960b3c39-7a73-49a6-ab68-056e4a1c313d IM-15332-5579 430597 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.976
comment: comment:mint
comment: author-confidence:z-score: 0.251073489718436
data source: intact
participant: Protein uniprotkb P43621 identity 1529029541702
participant: Protein uniprotkb P41810 identity 1529029541703

RelationshipXref interpro IPR018168
type: RelationshipXref
id: IPR018168
db: interpro

UnificationXref uniprot knowledgebase P50095
type: UnificationXref
id: P50095
db: uniprot knowledgebase

ExperimentalForm f26926d4-926a-43a7-a57f-9bf3220531a5
type: ExperimentalForm
experimental feature: ModificationFeature ba2a5212-3d4b-47ff-8274-21f064089b7c 432843
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref go GO 0070822
type: RelationshipXref
id: GO:0070822
db: gene ontology

RelationshipXref go GO 0006338
type: RelationshipXref
id: GO:0006338
db: gene ontology

RelationshipXref go GO 0006337
type: RelationshipXref
id: GO:0006337
db: gene ontology

RelationshipXref go GO 0006335
type: RelationshipXref
id: GO:0006335
db: gene ontology

ExperimentalForm 12cb80b1-a628-43a3-ac49-41e04b0a0b42
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref sgd S000000022
type: RelationshipXref
id: S000000022
db: sgd

RelationshipXref interpro IPR011989
type: RelationshipXref
id: IPR011989
db: interpro

Evidence 9ea7a149-e75a-49a0-8280-659696487adb IM-15332-5188 433485 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm 89a5d202-a645-4ae0-8ef3-818249c01efd
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref refseq NP 012198 3
type: RelationshipXref
id: NP_012198.3
db: refseq

RelationshipXref go GO 0070816
type: RelationshipXref
id: GO:0070816
db: gene ontology

UnificationXref mint MINT-2207798
type: UnificationXref
id: MINT-2207798
db: mint

RelationshipXref go GO 0006325
type: RelationshipXref
id: GO:0006325
db: gene ontology

RelationshipXref go GO 0046015
type: RelationshipXref
id: GO:0046015
db: gene ontology

rpb11-rpo21
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-8419 imex-primary
xref: RelationshipXref intact EBI-7526714 identity
xref: UnificationXref mint MINT-2203335
evidence: Evidence 355c0a76-4f9e-4a90-8750-95cad72ce3ae IM-15332-8419 432185 430156
interaction type: physical association
comment: author-confidence:z-score: 1.58459449127424
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.968
data source: intact
participant: Protein uniprotkb P38902 identity 1529029542496
participant: Protein uniprotkb P04050 identity 1529029542497

RelationshipXref intact EBI-7519982 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7519982
db: intact

UnificationXref uniprot knowledgebase P17629
type: UnificationXref
id: P17629
db: uniprot knowledgebase

RelationshipXref mint P16664
type: RelationshipXref
id: P16664
db: mint

RelationshipXref reactome R-SCE-174411
type: RelationshipXref
id: R-SCE-174411
db: reactome

ExperimentalForm cfefb6f7-f601-4081-93ab-daefd4ec55b1
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

Evidence 1af43429-bba4-4882-a7bd-cde52067b3c8 IM-15332-9202 431589 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref go GO 0006312
type: RelationshipXref
id: GO:0006312
db: gene ontology

RelationshipXref go GO 0006310
type: RelationshipXref
id: GO:0006310
db: gene ontology

RelationshipXref rcsb pdb 2K3Y
type: RelationshipXref
id: 2K3Y
db: protein data bank

RelationshipXref rcsb pdb 2K3X
type: RelationshipXref
id: 2K3X
db: protein data bank

ExperimentalForm 49d7b4e7-d8eb-4cac-9ec1-434dfba00dc7
type: ExperimentalForm
experimental feature: ModificationFeature 06c56548-9b15-49d2-8e3a-dc6dd2438bf0 430523
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7526003 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7526003
db: intact

RelationshipXref go GO 0006303
type: RelationshipXref
id: GO:0006303
db: gene ontology

RelationshipXref intact EBI-18520 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-18520
db: intact

RelationshipXref imex IM-15332-12867 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12867
db: imex

RelationshipXref sgd S000005133
type: RelationshipXref
id: S000005133
db: sgd

ExperimentalForm db646026-75ce-44a4-9e28-64b469cf3f04
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref go GO 0042826
type: RelationshipXref
id: GO:0042826
db: gene ontology

RelationshipXref intact EBI-7517054 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7517054
db: intact

RelationshipXref intact EBI-7535752 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7535752
db: intact

ExperimentalForm 4014c9a6-fd73-4922-8491-8e52b9f45ba2
type: ExperimentalForm
experimental feature: ModificationFeature b61cf3ef-fbb2-4f93-b422-d16d21555a0d 432324
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

Evidence 6868a0d1-9fb8-4373-9f7b-a5e1f29c6ebf IM-15332-4766 430997 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

Evidence c34bbaa4-4d7c-4afb-86d4-265ea49a7c59 IM-15332-9620 433113 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

lte1_yeast
type: Protein
evidence: Evidence 52fc71b6-740b-4e3b-9daf-14434a620931 p 430808
entity reference: P07866
name: Guanine nucleotide exchange factor LTE1
comment: psi-mi participant
data source: intact

rco1-nop1
type: MolecularInteraction
xref: UnificationXref mint MINT-2195357
xref: RelationshipXref intact EBI-7515238 identity
xref: RelationshipXref imex IM-15332-2341 imex-primary
evidence: Evidence f5a61c56-1b47-43a1-9305-33d76e94d4f5 IM-15332-2341 430413 430156
interaction type: physical association
comment: author-confidence:z-score: 8.65348315878319
comment: author-confidence:reliability score: 0.989
comment: comment:homomint
comment: comment:mint
data source: intact
participant: fbrl_yeast
participant: rco1_yeast

RelationshipXref rcsb pdb 1G7C
type: RelationshipXref
id: 1G7C
db: protein data bank

RelationshipXref intact EBI-15919 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-15919
db: intact

RelationshipXref refseq NP 013791 1
type: RelationshipXref
id: NP_013791.1
db: refseq

RelationshipXref imex IM-15332-3182 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-3182
db: imex

RelationshipXref uniprotkb D6VRX5 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VRX5
db: uniprot knowledgebase

ExperimentalForm f91b6644-3d00-480a-a7bb-86f1a54f18bf
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref mint MINT-2200436
type: UnificationXref
id: MINT-2200436
db: mint

rim13_yeast
type: Protein
evidence: Evidence 66f90dc1-f4d0-4ca6-a3e4-73ed4ca5d830 p 431103
entity reference: Q03792
name: Calpain-like protease 1
comment: psi-mi participant
data source: intact

RelationshipXref go GO 0035621
type: RelationshipXref
id: GO:0035621
db: gene ontology

UnificationXref mint MINT-2207744
type: UnificationXref
id: MINT-2207744
db: mint

RelationshipXref imex IM-15332-10021 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-10021
db: imex

Evidence f91455eb-db3a-4b4d-b0af-7957a05bf657 IM-15332-3586 431921 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref rcsb pdb 1G65
type: RelationshipXref
id: 1G65
db: protein data bank

ExperimentalForm 1c6d8f7e-405c-4f29-a44b-e4c9e8e0f6ce
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref mint MINT-2206393
type: UnificationXref
id: MINT-2206393
db: mint

prs10_yeast
type: Protein
evidence: Evidence 6266e58c-02ed-4d7a-bfff-151aaa4ef808 p 433722
entity reference: P53549
name: 26S proteasome subunit RPT4
comment: psi-mi participant
data source: intact

ExperimentalForm e20cf27b-edd3-4866-8eb4-2ac9f579f7e2
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

Evidence 5cacbd6f-a03c-4862-af10-d9a044c511aa IM-15332-6772 430677 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

med9_yeast
type: Protein
evidence: Evidence 1034d451-8506-4563-9abf-653243b01185 p 431018
entity reference: med9_yeast
name: Mediator of RNA polymerase II transcription subunit 9
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 1TWC
type: RelationshipXref
id: 1TWC
db: protein data bank

ExperimentalForm 6fd47448-9448-495c-8d16-7b12be1b9364
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref refseq NP 011445 1
type: RelationshipXref
id: NP_011445.1
db: refseq

UnificationXref mint MINT-2198996
type: UnificationXref
id: MINT-2198996
db: mint

RelationshipXref reactome R-SCE-3214847
type: RelationshipXref
id: R-SCE-3214847
db: reactome

ExperimentalForm 2c0af065-ba23-4142-a5c9-d6539f7bf820
type: ExperimentalForm
experimental feature: ModificationFeature 008a6ab6-7eb1-4c8d-99d7-fc7c8f24412c 430779
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm ea913c28-edc7-43ef-8a3e-943d7155245e
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref reactome R-SCE-3214841
type: RelationshipXref
id: R-SCE-3214841
db: reactome

UnificationXref mint MINT-2207726
type: UnificationXref
id: MINT-2207726
db: mint

ExperimentalForm 531bbae3-9ea7-4130-8a9c-84401ffe3797
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref mint MINT-2201804
type: UnificationXref
id: MINT-2201804
db: mint

UnificationXref mint MINT-2206375
type: UnificationXref
id: MINT-2206375
db: mint

rim13_yeast
type: Protein
evidence: Evidence c03d12ea-60a0-4ec8-8f6c-cbd27cb8b31a p 431099
entity reference: Q03792
name: Calpain-like protease 1
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-5174 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5174
db: imex

RelationshipXref imex IM-15332-10437 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-10437
db: imex

RelationshipXref intact EBI-7528381 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7528381
db: intact

ExperimentalForm 32abc0b3-f323-427d-97db-5f451a213c4d
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref uniprotkb D6W2K8 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6W2K8
db: uniprot knowledgebase

rmd8-hsc82-1
type: MolecularInteraction
xref: UnificationXref mint MINT-2199464
xref: RelationshipXref intact EBI-7520349 identity
xref: RelationshipXref imex IM-15332-12048 imex-primary
evidence: Evidence 778bcfe2-e230-4228-9c50-37e126ddafab IM-15332-12048 431325 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.985
comment: author-confidence:z-score: 4.09931482887045
comment: comment:mint
data source: intact
participant: Protein uniprotkb P43620 identity 1529029542066
participant: Protein uniprotkb P15108 identity 1529029542067

eif3c_yeast
type: ProteinReference
sequence: MSRFFSSNYEYDVASSSSEEDLLSSSEEDLLSSSSSESELDQESDDSFFNESESESEADVDSDDSDAKPYGPDWFKKSEFRKQGGGSNKFLKSSNYDSSDEESDEEDGKKVVKSAKEKLLDEMQDVYNKISQAENSDDWLTISNEFDLISRLLVRAQQQNWGTPNIFIKVVAQVEDAVNNTQQADLKNKAVARAYNTTKQRVKKVSRENEDSMAKFRNDPESFDKEPTADLDISANGFTISSSQGNDQAVQEDFFTRLQTIIDSRGKKTVNQQSLISTLEELLTVAEKPYEFIMAYLTLIPSRFDASANLSYQPIDQWKSSFNDISKLLSILDQTIDTYQVNEFADPIDFIEDEPKEDSDGVKRILGSIFSFVERLDDEFMKSLLNIDPHSSDYLIRLRDEQSIYNLILRTQLYFEATLKDEHDLERALTRPFVKRLDHIYYKSENLIKIMETAAWNIIPAQFKSKFTSKDQLDSADYVDNLIDGLSTILSKQNNIAVQKRAILYNIYYTALNKDFQTAKDMLLTSQVQTNINQFDSSLQILFNRVVVQLGLSAFKLCLIEECHQILNDLLSSSHLREILGQQSLHRISLNSSNNASADERARQCLPYHQHINLDLIDVVFLTCSLLIEIPRMTAFYSGIKVKRIPYSPKSIRRSLEHYDKLSFQGPPETLRDYVLFAAKSMQKGNWRDSVKYLREIKSWALLPNMETVLNSLTERVQVESLKTYFFSFKRFYSSFSVAKLAELFDLPENKVVEVLQSVIAELEIPAKLNDEKTIFVVEKGDEITKLEEAMVKLNKEYKIAKERLNPPSNRR
xref: RelationshipXref sgd S000004926
xref: RelationshipXref reactome R-SCE-72695
xref: RelationshipXref dip DIP-1470N
xref: RelationshipXref interpro IPR000717
xref: RelationshipXref intact EBI-8965 identity
xref: UnificationXref uniprot knowledgebase P32497
xref: RelationshipXref reactome R-SCE-156827
xref: RelationshipXref go GO 0005737
xref: RelationshipXref go GO 0006413
xref: RelationshipXref rcsb pdb 4U1C
xref: RelationshipXref rcsb pdb 5H7U
xref: RelationshipXref go GO 0043614
xref: RelationshipXref go GO 0031369
xref: RelationshipXref interpro IPR008905
xref: RelationshipXref refseq NP 014040 1
xref: RelationshipXref go GO 0003743
xref: RelationshipXref reactome R-SCE-72702
xref: RelationshipXref interpro IPR027516
xref: RelationshipXref rcsb pdb 3JAP
xref: RelationshipXref uniprotkb D6W0D6 secondary-ac
xref: RelationshipXref go GO 0010494
xref: RelationshipXref go GO 0005852
xref: RelationshipXref mint P32497
organism: http://identifiers.org/taxonomy/559292
name: YMR309C
name: YM9952.11C
name: Nuclear transport protein NIP1
name: Eukaryotic translation initiation factor 3 subunit C
name: Translation initiation factor eIF3, p93 subunit
name: NIP1
name: YM9924.01C
name: Eukaryotic translation initiation factor 3 93 kDa subunit

RelationshipXref imex IM-15332-1957 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1957
db: imex

RelationshipXref rcsb pdb 3NFH
type: RelationshipXref
id: 3NFH
db: protein data bank

ExperimentalForm a2991856-fc5a-4875-96af-416c37d24209
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7522058 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7522058
db: intact

RelationshipXref rcsb pdb 5AHJ
type: RelationshipXref
id: 5AHJ
db: protein data bank

ExperimentalForm 7ef8739f-5aa1-4347-b990-9b1698a1a074
type: ExperimentalForm
experimental feature: ModificationFeature 82b788e6-946a-4b3f-8e4c-4a100409b96f 433523
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7521327 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7521327
db: intact

UnificationXref mint MINT-2207708
type: UnificationXref
id: MINT-2207708
db: mint

UnificationXref uniprot knowledgebase P53131
type: UnificationXref
id: P53131
db: uniprot knowledgebase

ExperimentalForm 44619bb2-db96-4601-9509-7a54521de59d
type: ExperimentalForm
experimental feature: ModificationFeature 9c65c666-b89f-4293-a4a3-3fbcaf3742d5 431047
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

Evidence a1f03f8b-a3aa-4b57-88f5-cc40e42826ad IM-15332-2761 433613 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref mint MINT-2195681
type: UnificationXref
id: MINT-2195681
db: mint

UnificationXref uniprot knowledgebase P53135
type: UnificationXref
id: P53135
db: uniprot knowledgebase

UnificationXref mint MINT-2201822
type: UnificationXref
id: MINT-2201822
db: mint

ExperimentalForm 80e6ad95-c192-4edd-a643-7a118dc70c53
type: ExperimentalForm
experimental feature: ModificationFeature fbe60e12-6c28-4be4-937f-0a40fa8add49 433244
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpa2_yeast
type: Protein
evidence: Evidence 8f188902-f947-4fa1-8073-ee4f89e93cc5 p 432746
entity reference: rpa2_yeast
name: DNA-directed RNA polymerase I subunit RPA135
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2206357
type: UnificationXref
id: MINT-2206357
db: mint

RelationshipXref reactome R-SCE-3214815
type: RelationshipXref
id: R-SCE-3214815
db: reactome

RelationshipXref intact EBI-7539218 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7539218
db: intact

Evidence 48f6adfb-adf6-4ada-a2e2-74000622db6e IM-15332-12049 431473 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm c6e5e59c-11a7-4a80-aa3c-9e8b9b953786
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7522011 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7522011
db: intact

rpa1_yeast
type: Protein
evidence: Evidence 3e81d26c-232e-453d-a843-ab407fef7d76 p 432776
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 1G0U
type: RelationshipXref
id: 1G0U
db: protein data bank

RelationshipXref intact EBI-7538933 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7538933
db: intact

RelationshipXref intact EBI-7520687 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7520687
db: intact

ExperimentalForm 57e7892e-55d6-41f4-8951-f8d8a22caee9
type: ExperimentalForm
experimental feature: ModificationFeature 75d77239-460b-4d5f-9127-412eac42d8ed 430928
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref go GO 0034221
type: RelationshipXref
id: GO:0034221
db: gene ontology

UnificationXref mint MINT-2200490
type: UnificationXref
id: MINT-2200490
db: mint

RelationshipXref rcsb pdb 5UWT
type: RelationshipXref
id: 5UWT
db: protein data bank

RelationshipXref intact EBI-7542880 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7542880
db: intact

RelationshipXref rcsb pdb 3ND2
type: RelationshipXref
id: 3ND2
db: protein data bank

ExperimentalForm 9bc748ff-142c-4ec6-bc04-af2a8772abb9
type: ExperimentalForm
experimental feature: ModificationFeature 2a78e3e5-4b79-4ee0-876b-3ed3f07e1d06 430708
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref rcsb pdb 1FNT
type: RelationshipXref
id: 1FNT
db: protein data bank

ExperimentalForm 608f932a-45e8-44b0-98ff-a2474c71085a
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref mint MINT-2206339
type: UnificationXref
id: MINT-2206339
db: mint

Evidence 0909fe1e-d5d9-420d-81e8-cf83448deaf8 IM-15332-1581 431689 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

copb_yeast
type: Protein
evidence: Evidence cc2df864-743b-4a00-a94c-7959393c0e6c p 430684
entity reference: P41810
name: Coatomer subunit beta
comment: psi-mi participant
data source: intact

ExperimentalForm 55da2768-77d3-4dee-acc6-8abfe4dd0764
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 83cc6d31-f96a-40d9-9a42-33961a494d7a
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpc82-rpc53-1
type: MolecularInteraction
xref: RelationshipXref intact EBI-7537261 identity
xref: RelationshipXref imex IM-15332-6387 imex-primary
xref: UnificationXref mint MINT-2208230
evidence: Evidence 1187a5f4-bfd2-45a7-9403-79153b412fb9 IM-15332-6387 433261 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.981
comment: author-confidence:z-score: 0.330566586449653
comment: comment:mint
data source: intact
participant: Protein uniprotkb P32349 identity 1529029543035
participant: rpc4_yeast

ExperimentalForm a26c5796-699d-4fbe-a8b6-12e7c2b649b3
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 83681061-b65c-45b5-be97-2a451c2e3544
type: ExperimentalForm
experimental feature: ModificationFeature b38c12cb-ab49-435e-9218-b436230805df 433419
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpg1-ssc1
type: MolecularInteraction
xref: UnificationXref mint MINT-2209112
xref: RelationshipXref intact EBI-7539134 identity
xref: RelationshipXref imex IM-15332-9215 imex-primary
evidence: Evidence f97a91f2-e3c2-449a-97bc-de684d970aff IM-15332-9215 433457 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.611
comment: comment:mint
comment: author-confidence:z-score: 0.366808313419167
data source: intact
participant: Protein uniprotkb P0CS91 identity 1529029543132
participant: Protein uniprotkb P38249 identity 1529029543133

UnificationXref mint MINT-2201858
type: UnificationXref
id: MINT-2201858
db: mint

UnificationXref mint MINT-2206321
type: UnificationXref
id: MINT-2206321
db: mint

RelationshipXref sgd S000002789
type: RelationshipXref
id: S000002789
db: sgd

ExperimentalForm 7e3da00f-dac5-486c-97cc-fc75d0553b72
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm bed99542-0efa-4493-a8b9-7b4066cc2308
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref mint MINT-2195645
type: UnificationXref
id: MINT-2195645
db: mint

RelationshipXref rcsb pdb 4QZZ
type: RelationshipXref
id: 4QZZ
db: protein data bank

RelationshipXref rcsb pdb 4QZX
type: RelationshipXref
id: 4QZX
db: protein data bank

RelationshipXref rcsb pdb 4QZW
type: RelationshipXref
id: 4QZW
db: protein data bank

RelationshipXref imex IM-15332-6372 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-6372
db: imex

RelationshipXref sgd S000001369
type: RelationshipXref
id: S000001369
db: sgd

RelationshipXref sgd S000002629
type: RelationshipXref
id: S000002629
db: sgd

RelationshipXref dip DIP-3988N
type: RelationshipXref
id: DIP-3988N
db: database of interacting proteins

ExperimentalForm adb669bc-29ad-4127-926b-1e753273f3e4
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref sgd S000004665
type: RelationshipXref
id: S000004665
db: sgd

RelationshipXref intact EBI-7533987 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7533987
db: intact

RelationshipXref sgd S000005963
type: RelationshipXref
id: S000005963
db: sgd

RelationshipXref imex IM-15332-7211 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-7211
db: imex

rpc19-rpc40-2
type: MolecularInteraction
xref: RelationshipXref intact EBI-7532904 identity
xref: UnificationXref mint MINT-2206051
xref: RelationshipXref imex IM-15332-8819 imex-primary
evidence: Evidence d1c9a7ae-cd3e-4af3-98c4-d71a214673e8 IM-15332-8819 432777 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 9.78913692938672
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P28000 identity 1529029542793
participant: rpac1_yeast

rpc40-rpc37-1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-406 imex-primary
xref: UnificationXref mint MINT-2207654
xref: RelationshipXref intact EBI-7536054 identity
evidence: Evidence ffbe5b9a-91de-4887-bfee-8342a8c39725 IM-15332-406 433133 430156
interaction type: physical association
comment: author-confidence:z-score: 1.09581110860623
comment: author-confidence:reliability score: 0.983
comment: comment:mint
data source: intact
participant: Protein uniprotkb P36121 identity 1529029542970
participant: Protein uniprotkb P07703 identity 1529029542971

rpb11-rpb5-1
type: MolecularInteraction
xref: RelationshipXref intact EBI-7527098 identity
xref: UnificationXref mint MINT-2203659
xref: RelationshipXref imex IM-15332-2749 imex-primary
evidence: Evidence dec88c04-caea-4de7-9257-83c5056a9ef6 IM-15332-2749 432257 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 0.505239856694976
comment: comment:mint
comment: author-confidence:reliability score: 0.968
data source: intact
participant: rpab1_yeast
participant: Protein uniprotkb P38902 identity 1529029542532

RelationshipXref intact EBI-29516 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-29516
db: intact

RelationshipXref uniprotkb Q07595 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: Q07595
db: uniprot knowledgebase

RelationshipXref imex IM-15332-8015 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-8015
db: imex

RelationshipXref rcsb pdb 4QZ6
type: RelationshipXref
id: 4QZ6
db: protein data bank

RelationshipXref rcsb pdb 4QZ5
type: RelationshipXref
id: 4QZ5
db: protein data bank

RelationshipXref rcsb pdb 4QZ4
type: RelationshipXref
id: 4QZ4
db: protein data bank

RelationshipXref rcsb pdb 4QZ3
type: RelationshipXref
id: 4QZ3
db: protein data bank

UnificationXref mint MINT-2201876
type: UnificationXref
id: MINT-2201876
db: mint

RelationshipXref rcsb pdb 4QZ1
type: RelationshipXref
id: 4QZ1
db: protein data bank

Evidence a3dd5448-855a-4dee-a725-640d7c676245 IM-15332-11251 432245 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref mint MINT-2206303
type: UnificationXref
id: MINT-2206303
db: mint

rpa190-rpc40-1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-10436 imex-primary
xref: UnificationXref mint MINT-2201012
xref: RelationshipXref intact EBI-7522681 identity
evidence: Evidence aeae18df-2ea5-45a1-ab9f-27c2df0f97eb IM-15332-10436 431669 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 9.5803359367122
comment: comment:mint
comment: author-confidence:reliability score: 0.97
data source: intact
participant: rpa1_yeast
participant: Protein uniprotkb P07703 identity 1529029542239

ExperimentalForm 789bb57e-b259-46e4-8659-f4af72bf8b40
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 839db76b-807f-433a-afbb-1ccff39b0513
type: ExperimentalForm
experimental feature: ModificationFeature 3afa056b-8f07-4d70-b86d-50f3da836c0d 431943
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm bcecb0f3-d152-4bd4-bbe9-3f7486570be2
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref mint MINT-2195627
type: UnificationXref
id: MINT-2195627
db: mint

ExperimentalForm fb964b5c-53af-4bc4-b1dd-c1cc49cdac95
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7536359 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7536359
db: intact

RelationshipXref intact EBI-7520448 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7520448
db: intact

rpc19-ret1-7
type: MolecularInteraction
xref: RelationshipXref intact EBI-7533913 identity
xref: UnificationXref mint MINT-2206375
xref: RelationshipXref imex IM-15332-12493 imex-primary
evidence: Evidence c4731f13-4a33-412d-8304-838f7fe6d8ca IM-15332-12493 432849 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 2.58841327775444
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P22276 identity 1529029542828
participant: Protein uniprotkb P28000 identity 1529029542829

rpa135-rpc34-5
type: MolecularInteraction
xref: RelationshipXref intact EBI-7522027 identity
xref: UnificationXref mint MINT-2200508
xref: RelationshipXref imex IM-15332-7632 imex-primary
evidence: Evidence 597cac88-4dcf-4866-96f3-071b947c4582 IM-15332-7632 431557 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.688
comment: comment:mint
comment: author-confidence:z-score: 0.0125183387859064
data source: intact
participant: Protein uniprotkb P22138 identity 1529029542183
participant: rpc6_yeast

RelationshipXref rcsb pdb 4QXJ
type: RelationshipXref
id: 4QXJ
db: protein data bank

RelationshipXref imex IM-15332-6788 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-6788
db: imex

eif3a_yeast
type: Protein
evidence: Evidence e2f90031-616f-4cc4-b22e-7119a6f4d5e1 p 433418
entity reference: P38249
name: Eukaryotic translation initiation factor 3 subunit A
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 4QWU
type: RelationshipXref
id: 4QWU
db: protein data bank

eif3a_yeast
type: Protein
evidence: Evidence 7f2f5979-2251-4f55-8b85-d7f8b2e31425 p 433423
entity reference: P38249
name: Eukaryotic translation initiation factor 3 subunit A
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 4QWR
type: RelationshipXref
id: 4QWR
db: protein data bank

RelationshipXref rcsb pdb 4QWL
type: RelationshipXref
id: 4QWL
db: protein data bank

RelationshipXref imex IM-15332-7627 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-7627
db: imex

RelationshipXref rcsb pdb 4QWJ
type: RelationshipXref
id: 4QWJ
db: protein data bank

RelationshipXref rcsb pdb 4QWI
type: RelationshipXref
id: 4QWI
db: protein data bank

RelationshipXref rcsb pdb 4QWG
type: RelationshipXref
id: 4QWG
db: protein data bank

RelationshipXref dip DIP-5916N
type: RelationshipXref
id: DIP-5916N
db: database of interacting proteins

rpl1a-tef1
type: MolecularInteraction
xref: RelationshipXref intact EBI-7540787 identity
xref: UnificationXref mint MINT-2209832
xref: RelationshipXref imex IM-15332-1965 imex-primary
evidence: Evidence 04d703a4-1626-4e58-8efb-11d160eddf10 IM-15332-1965 433617 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 3.59154227577728
comment: comment:mint
comment: author-confidence:reliability score: 0.681
data source: intact
participant: Protein uniprotkb P02994 identity 1529029543212
participant: Protein uniprotkb P53030 identity 1529029543213

RelationshipXref intact EBI-7520401 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7520401
db: intact

rpb11-rpb3
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-7204 imex-primary
xref: RelationshipXref intact EBI-7526663 identity
xref: UnificationXref mint MINT-2203299
evidence: Evidence 6d8c14d6-8692-42df-ad7b-0fd2f0ace19a IM-15332-7204 432177 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 9.57114826202787
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P16370 identity 1529029542493
participant: Protein uniprotkb P38902 identity 1529029542492

UnificationXref mint MINT-2196204
type: UnificationXref
id: MINT-2196204
db: mint

RelationshipXref imex IM-15332-9203 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-9203
db: imex

RelationshipXref rcsb pdb 4QVY
type: RelationshipXref
id: 4QVY
db: protein data bank

eif3a_yeast
type: Protein
evidence: Evidence 47a6bc2e-2631-486d-bc86-f3f52d61b4dc p 433435
entity reference: P38249
name: Eukaryotic translation initiation factor 3 subunit A
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 4QVW
type: RelationshipXref
id: 4QVW
db: protein data bank

RelationshipXref rcsb pdb 4QVV
type: RelationshipXref
id: 4QVV
db: protein data bank

RelationshipXref rcsb pdb 4QW6
type: RelationshipXref
id: 4QW6
db: protein data bank

RelationshipXref rcsb pdb 4QW5
type: RelationshipXref
id: 4QW5
db: protein data bank

RelationshipXref rcsb pdb 4QW4
type: RelationshipXref
id: 4QW4
db: protein data bank

RelationshipXref rcsb pdb 4QW3
type: RelationshipXref
id: 4QW3
db: protein data bank

RelationshipXref rcsb pdb 4QVQ
type: RelationshipXref
id: 4QVQ
db: protein data bank

RelationshipXref rcsb pdb 4QW1
type: RelationshipXref
id: 4QW1
db: protein data bank

RelationshipXref rcsb pdb 4QW0
type: RelationshipXref
id: 4QW0
db: protein data bank

rpc9_yeast
type: Protein
evidence: Evidence 1138661d-2325-4fb4-b8a1-16723739e036 p 432884
entity reference: rpc9_yeast
name: DNA-directed RNA polymerase III subunit RPC9
comment: psi-mi participant
data source: intact

ExperimentalForm 2c599005-a5d4-486a-9eda-c4ff1d8770b0
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref rcsb pdb 4QVL
type: RelationshipXref
id: 4QVL
db: protein data bank

ExperimentalForm ff676777-3559-450d-958c-a5c01783a020
type: ExperimentalForm
experimental feature: ModificationFeature 8bc328a3-ebd8-460f-98f4-12763f1fa3c2 431084
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm e3a9de41-6dc9-4c0e-ac24-c1d78827a276
type: ExperimentalForm
experimental feature: ModificationFeature 3a271795-0fa4-4fab-8c58-4e0a9ded441d 430504
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpa14-rpa43-1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-7633 imex-primary
xref: UnificationXref mint MINT-2200544
xref: RelationshipXref intact EBI-7522058 identity
evidence: Evidence fcd05c79-3707-4f1a-8eef-04984f7c35b8 IM-15332-7633 431565 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.989
comment: author-confidence:z-score: 6.99860243432667
comment: comment:mint
data source: intact
participant: rpa43_yeast
participant: rpa14_yeast

RelationshipXref imex IM-15332-3590 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-3590
db: imex

ExperimentalForm 26a6a988-02c7-4a22-83e1-0f9e0cc6a63a
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpd3-rco1-2
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-8432 imex-primary
xref: UnificationXref mint MINT-2208770
xref: RelationshipXref intact EBI-7538489 identity
evidence: Evidence 60c8356f-3158-456c-a033-d488d4842e08 IM-15332-8432 433381 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.99
comment: author-confidence:z-score: 0.644279128667807
data source: intact
participant: Protein uniprotkb Q04779 identity 1529029543094
participant: rpd3_yeast

RelationshipXref rcsb pdb 4QUY
type: RelationshipXref
id: 4QUY
db: protein data bank

RelationshipXref rcsb pdb 4QUX
type: RelationshipXref
id: 4QUX
db: protein data bank

RelationshipXref rcsb pdb 4QV8
type: RelationshipXref
id: 4QV8
db: protein data bank

RelationshipXref rcsb pdb 4QV7
type: RelationshipXref
id: 4QV7
db: protein data bank

RelationshipXref rcsb pdb 4QV6
type: RelationshipXref
id: 4QV6
db: protein data bank

RelationshipXref rcsb pdb 4QV4
type: RelationshipXref
id: 4QV4
db: protein data bank

RelationshipXref imex IM-15332-1223 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1223
db: imex

RelationshipXref rcsb pdb 4QV1
type: RelationshipXref
id: 4QV1
db: protein data bank

rfa1_yeast
type: Protein
evidence: Evidence b3a4a5db-ea8c-4795-9569-7377d136b887 p 430776
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 6EM3
type: RelationshipXref
id: 6EM3
db: protein data bank

RelationshipXref rcsb pdb 6EM5
type: RelationshipXref
id: 6EM5
db: protein data bank

RelationshipXref rcsb pdb 6ELZ
type: RelationshipXref
id: 6ELZ
db: protein data bank

rpb10-rpa135
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-8811 imex-primary
xref: UnificationXref mint MINT-2201930
xref: RelationshipXref intact EBI-7523989 identity
evidence: Evidence 4782a379-455f-4eaa-b1b0-5cdf28da44c6 IM-15332-8811 431873 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.932
comment: author-confidence:z-score: 0.0549941418879802
comment: comment:mint
data source: intact
participant: Protein uniprotkb P22138 identity 1529029542341
participant: rpab5_yeast

RelationshipXref intact EBI-9145 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-9145
db: intact

RelationshipXref reactome R-SCE-4551638
type: RelationshipXref
id: R-SCE-4551638
db: reactome

rpac2_yeast
type: Protein
evidence: Evidence 5799e171-e69f-480f-aa73-4dfc1de47d19 p 432811
entity reference: P28000
name: DNA-directed RNA polymerases I and III subunit RPAC2
comment: psi-mi participant
data source: intact

rfa1_yeast
type: Protein
evidence: Evidence 5c7e64b0-6c35-4633-b626-11238de9133d p 430772
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

rfa1_yeast
type: Protein
evidence: Evidence 1a9ff672-a6a9-402a-bb34-e48a30cfe4a6 p 430768
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-7637 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-7637
db: imex

rfa1_yeast
type: Protein
evidence: Evidence 7deb9c22-b2fc-4033-b771-7e456ca67e2e p 430762
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

rfa1_yeast
type: Protein
evidence: Evidence 637e4245-dc6d-452d-a5f1-2af4e1ffc991 p 430760
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 2JA8
type: RelationshipXref
id: 2JA8
db: protein data bank

RelationshipXref rcsb pdb 2JA7
type: RelationshipXref
id: 2JA7
db: protein data bank

rfa1_yeast
type: Protein
evidence: Evidence 4e465585-47c5-48c4-bfd0-2f2afa4dad99 p 430754
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 2JA5
type: RelationshipXref
id: 2JA5
db: protein data bank

UnificationXref mint MINT-2209436
type: UnificationXref
id: MINT-2209436
db: mint

Evidence 4dfc610c-330c-4183-899d-27bb00da8c8f IM-15332-3173 432325 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref imex IM-15332-9619 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-9619
db: imex

Evidence fad1c2c3-0aa9-4319-a6d1-a7b8d72d8e2e IM-15332-399 432337 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpa1_yeast
type: Protein
evidence: Evidence 9b977c02-4ea4-41d9-affc-e6645ff572cc p 431755
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

ExperimentalForm 992f014a-0ecb-4c4f-9e06-8c807e778faa
type: ExperimentalForm
experimental feature: ModificationFeature 70943df1-b51e-4e0c-a55e-cd16ad644e7f 431647
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

eif3a_yeast
type: Protein
evidence: Evidence ac465968-4f00-447b-9910-13769e710400 p 433495
entity reference: P38249
name: Eukaryotic translation initiation factor 3 subunit A
comment: psi-mi participant
data source: intact

rfa1_yeast
type: Protein
evidence: Evidence 8a8d7f5a-da0f-41bd-9d01-b01b5b309a9d p 430752
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

RelationshipXref go GO 0006334
type: RelationshipXref
id: GO:0006334
db: gene ontology

RelationshipXref mint Q12495
type: RelationshipXref
id: Q12495
db: mint

rfa1_yeast
type: Protein
evidence: Evidence 60f4e1ca-66d7-4c42-beca-0fda0f8e412d p 430743
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

ExperimentalForm 8ef96a18-13a0-4eae-8016-7556bd54f98b
type: ExperimentalForm
experimental feature: ModificationFeature 0d4e82bb-417c-49ac-a2fe-afa0d65eb9de 431448
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rfa1_yeast
type: Protein
evidence: Evidence 69f523b2-4ab9-4812-b018-81e25111580a p 430739
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

eif3a_yeast
type: Protein
evidence: Evidence ab33ec1f-126a-49f9-a9c5-a3159c14c07f p 433511
entity reference: P38249
name: Eukaryotic translation initiation factor 3 subunit A
comment: psi-mi participant
data source: intact

rfa1_yeast
type: Protein
evidence: Evidence 31ec0c00-82bd-4970-ab90-af2ae9cda42f p 430735
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

rpc34-rpc82-1
type: MolecularInteraction
xref: UnificationXref mint MINT-2206736
xref: RelationshipXref imex IM-15332-11257 imex-primary
xref: RelationshipXref intact EBI-7534466 identity
evidence: Evidence 1d6b160f-6e0f-4389-9011-9b9165f7a4fa IM-15332-11257 432929 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.99
comment: author-confidence:z-score: 6.47238114085818
data source: intact
participant: Protein uniprotkb P32910 identity 1529029542868
participant: rpc3_yeast

RelationshipXref imex IM-15332-1572 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1572
db: imex

rpa49_yeast
type: Protein
evidence: Evidence 5fec8506-f96c-4450-b6ea-863b39a2c486 p 432014
entity reference: Q01080
name: DNA-directed RNA polymerase I subunit RPA49
comment: psi-mi participant
data source: intact

rpn1-rpn12-3
type: MolecularInteraction
xref: RelationshipXref intact EBI-7541685 identity
xref: UnificationXref mint MINT-2210156
xref: RelationshipXref imex IM-15332-8435 imex-primary
evidence: Evidence a6052abb-b83c-457c-93dd-0dcc76aed6e0 IM-15332-8435 433689 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 8.52463260634883
comment: author-confidence:reliability score: 0.983
comment: comment:mint
data source: intact
participant: Protein uniprotkb P32496 identity 1529029543249
participant: Protein uniprotkb P38764 identity 1529029543248

ExperimentalForm 52f3769c-e95e-4b8c-b8a0-805b88985df6
type: ExperimentalForm
experimental feature: ModificationFeature 67b3cacd-db2f-4e96-b8d3-4ef14c845cbe 431836
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

eif3a_yeast
type: Protein
evidence: Evidence fc330205-ff61-48b7-b65d-b14421d18636 p 433518
entity reference: P38249
name: Eukaryotic translation initiation factor 3 subunit A
comment: psi-mi participant
data source: intact

rfa1_yeast
type: Protein
evidence: Evidence c1163753-35e5-4f3b-9e15-5737948b625e p 430730
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

ExperimentalForm 34b31e58-92c7-4c1c-a819-0f8d60627b3b
type: ExperimentalForm
experimental feature: ModificationFeature 2f27787f-f30a-478f-b8c3-89474d41774e 432496
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rfa1_yeast
type: Protein
evidence: Evidence 90b0b4bd-7675-42fa-8598-7f09535c4044 p 430726
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

rfa1_yeast
type: Protein
evidence: Evidence d7c8fc99-8224-4dad-91fc-9967ebb3ceb9 p 430722
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

RelationshipXref go GO 0042802
type: RelationshipXref
id: GO:0042802
db: gene ontology

RelationshipXref imex IM-15332-8809 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-8809
db: imex

rfa1_yeast
type: Protein
evidence: Evidence 46dea9f3-eaf6-4c4a-b94a-c11737f3df67 p 430715
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7536264 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7536264
db: intact

rpa190-rpb5-2
type: MolecularInteraction
xref: UnificationXref mint MINT-2201192
xref: RelationshipXref imex IM-15332-12482 imex-primary
xref: RelationshipXref intact EBI-7523009 identity
evidence: Evidence 4ac60763-efd3-4553-81de-f6db39ea722f IM-15332-12482 431709 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:z-score: 2.44532048261935
comment: author-confidence:reliability score: 0.968
data source: intact
participant: rpab1_yeast
participant: Protein uniprotkb P10964 identity 1529029542258

RelationshipXref intact EBI-15815 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-15815
db: intact

RelationshipXref imex IM-15332-12064 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12064
db: imex

RelationshipXref uniprotkb D6VT28 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VT28
db: uniprot knowledgebase

RelationshipXref reactome R-SCE-416482
type: RelationshipXref
id: R-SCE-416482
db: reactome

eif3a_yeast
type: Protein
evidence: Evidence e0b8f94e-addb-4059-ac81-f00e6a582727 p 433534
entity reference: P38249
name: Eukaryotic translation initiation factor 3 subunit A
comment: psi-mi participant
data source: intact

rfa1_yeast
type: Protein
evidence: Evidence 238e35a6-a6f8-4e18-a9eb-d4756bef58d1 p 430711
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

rfa1_yeast
type: Protein
evidence: Evidence aa5abc2c-33b2-43f2-9418-e2eed4df35b6 p 430707
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

RelationshipXref sgd S000001346
type: RelationshipXref
id: S000001346
db: sgd

rfa1_yeast
type: Protein
evidence: Evidence f6119bbd-269e-4153-82dd-a527b28de97d p 430703
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

Evidence 0dc721c4-d37e-4287-ba55-a528ff3956d7 IM-15332-2738 431073 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

Evidence b3a33024-af66-4e02-9f3d-e07534a631c3 IM-15332-2740 431193 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rfa1_yeast
type: Protein
evidence: Evidence 84e83b70-0da9-4af0-8401-10fd646f974c p 430698
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

rfa1_yeast
type: Protein
evidence: Evidence c73dcab7-6e9a-408a-b073-e9f62df023b7 p 430694
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

ExperimentalForm 65d2f27f-ab45-4fe2-b269-0924bf094c95
type: ExperimentalForm
experimental feature: ModificationFeature 42440987-b51b-45a8-8087-583bc4de8747 431579
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ret2-cop1-1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-797 imex-primary
xref: RelationshipXref intact EBI-7515941 identity
xref: UnificationXref mint MINT-2196060
evidence: Evidence dc217d81-c0d6-48d1-9ecc-c34eb96d5e64 IM-15332-797 430569 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 0.229932495457728
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P53622 identity 1529029541688
participant: Protein uniprotkb P43621 identity 1529029541689

ExperimentalForm 594841ee-4769-4f02-9152-0e8e752d914f
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref refseq NP 011342 1
type: RelationshipXref
id: NP_011342.1
db: refseq

Evidence 467d9e20-6184-46f1-8c4a-3f98d3ffc523 IM-15332-8802 431017 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm 92de514d-74d7-4c6e-85d5-54220151b38c
type: ExperimentalForm
experimental feature: ModificationFeature c15af17a-8c4d-436f-b773-44c794f64924 433592
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rfa1_yeast
type: Protein
evidence: Evidence 0ea7c4fb-7f38-4ba4-b958-78424dfefb6b p 430691
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

RelationshipXref sgd S000001338
type: RelationshipXref
id: S000001338
db: sgd

RelationshipXref sgd S000001337
type: RelationshipXref
id: S000001337
db: sgd

rfa1_yeast
type: Protein
evidence: Evidence 3da80ccb-fe05-4a11-9a8b-a32119ddfb31 p 430686
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

RelationshipXref sgd S000001331
type: RelationshipXref
id: S000001331
db: sgd

RelationshipXref imex IM-15332-1582 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1582
db: imex

RelationshipXref refseq NP 116659 1
type: RelationshipXref
id: NP_116659.1
db: refseq

RelationshipXref go GO 0006298
type: RelationshipXref
id: GO:0006298
db: gene ontology

RelationshipXref intact EBI-7521247 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7521247
db: intact

RelationshipXref rcsb pdb 3MV3
type: RelationshipXref
id: 3MV3
db: protein data bank

RelationshipXref rcsb pdb 3MV2
type: RelationshipXref
id: 3MV2
db: protein data bank

rpab1_yeast
type: Protein
evidence: Evidence 832c16b0-5d07-47cf-9af4-b8068ec9da22 p 432674
entity reference: rpab1_yeast
name: DNA-directed RNA polymerases I, II, and III subunit RPABC1
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7520516 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7520516
db: intact

RelationshipXref interpro IPR019460
type: RelationshipXref
id: IPR019460
db: interpro

RelationshipXref rcsb pdb 4R18
type: RelationshipXref
id: 4R18
db: protein data bank

RelationshipXref sgd S000001328
type: RelationshipXref
id: S000001328
db: sgd

Evidence ee39b447-ee87-446c-b1e2-d7c5cacd6438 IM-15332-10432 431089 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref go GO 0006379
type: RelationshipXref
id: GO:0006379
db: gene ontology

RelationshipXref mint Q12451
type: RelationshipXref
id: Q12451
db: mint

Evidence c8463d3f-42f2-4c97-ace2-ca655420293c IM-15332-6382 432433 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref imex IM-15332-4403 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-4403
db: imex

Evidence 63dfcffa-54a7-438d-a4f7-511c15da1d86 IM-15332-390 431361 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref intact EBI-7526484 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7526484
db: intact

Evidence 1a85b6bc-0b10-453c-9040-5594f2521ca7 IM-15332-12488 432445 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref mint P38630
type: RelationshipXref
id: P38630
db: mint

RelationshipXref go GO 0006289
type: RelationshipXref
id: GO:0006289
db: gene ontology

UnificationXref mint MINT-2197628
type: UnificationXref
id: MINT-2197628
db: mint

RelationshipXref go GO 0006283
type: RelationshipXref
id: GO:0006283
db: gene ontology

Evidence db17e71c-1da5-4114-a87d-5c1ed77f218a IM-15332-6774 431461 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref go GO 0006281
type: RelationshipXref
id: GO:0006281
db: gene ontology

RelationshipXref interpro IPR014001
type: RelationshipXref
id: IPR014001
db: interpro

RelationshipXref intact EBI-7532320 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7532320
db: intact

UnificationXref mint MINT-2209490
type: UnificationXref
id: MINT-2209490
db: mint

RelationshipXref dip DIP-5290N
type: RelationshipXref
id: DIP-5290N
db: database of interacting proteins

RelationshipXref rcsb pdb 4R00
type: RelationshipXref
id: 4R00
db: protein data bank

RelationshipXref mint P38626
type: RelationshipXref
id: P38626
db: mint

set2_yeast
type: Protein
evidence: Evidence 26e94a6b-3b8e-4f2d-8932-6dadabd56628 p 430412
entity reference: P46995
name: Histone-lysine N-methyltransferase, H3 lysine-36 specific
comment: psi-mi participant
data source: intact

rgp1-tif34
type: MolecularInteraction
xref: RelationshipXref intact EBI-7518140 identity
xref: UnificationXref mint MINT-2197862
xref: RelationshipXref imex IM-15332-7193 imex-primary
evidence: Evidence 0b4b63cd-c221-4bdb-8d63-b7366348f482 IM-15332-7193 430969 430156
interaction type: physical association
comment: author-confidence:z-score: 5.70710114519106
comment: author-confidence:reliability score: 0.764
comment: comment:mint
data source: intact
participant: Protein uniprotkb P40217 identity 1529029541889
participant: Protein uniprotkb P16664 identity 1529029541888

Evidence 7351aaee-2746-41f3-bbe7-656bb5bee21c IM-15332-12496 433145 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ret2-sec26-11
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-12475 imex-primary
xref: UnificationXref mint MINT-2196456
xref: RelationshipXref intact EBI-7516488 identity
evidence: Evidence 8a230d73-5252-4964-975d-a3af1f564f56 IM-15332-12475 430657 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.976
comment: comment:mint
comment: author-confidence:z-score: 2.84696548175218
data source: intact
participant: Protein uniprotkb P41810 identity 1529029541732
participant: Protein uniprotkb P43621 identity 1529029541733

RelationshipXref go GO 0006279
type: RelationshipXref
id: GO:0006279
db: gene ontology

ExperimentalForm 547a45b7-8a67-4f24-b02b-7e130872d637
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

Evidence c1d32888-4bd9-4c1d-ab9b-e3c3efb8aca4 IM-15332-7646 432989 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref go GO 2000232
type: RelationshipXref
id: GO:2000232
db: gene ontology

RelationshipXref go GO 0006272
type: RelationshipXref
id: GO:0006272
db: gene ontology

rpab1_yeast
type: Protein
evidence: Evidence ed17cc65-4687-4e12-b3bb-30d242dccbf1 p 432636
entity reference: rpab1_yeast
name: DNA-directed RNA polymerases I, II, and III subunit RPABC1
comment: psi-mi participant
data source: intact

RelationshipXref go GO 0006270
type: RelationshipXref
id: GO:0006270
db: gene ontology

RelationshipXref intact EBI-8094 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-8094
db: intact

ExperimentalForm 55524f90-8f3b-4650-a01f-09977ceaf70e
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref sgd S000001305
type: RelationshipXref
id: S000001305
db: sgd

RelationshipXref imex IM-15332-12054 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12054
db: imex

RelationshipXref rcsb pdb 6EU1
type: RelationshipXref
id: 6EU1
db: protein data bank

ExperimentalForm 0a0ff2f7-9374-4c1f-87e9-b73d297e2019
type: ExperimentalForm
experimental feature: ModificationFeature 57a48e5b-a60a-4329-a559-ff1c9abdd802 431852
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref interpro IPR018098
type: RelationshipXref
id: IPR018098
db: interpro

RelationshipXref mint P38615
type: RelationshipXref
id: P38615
db: mint

RelationshipXref reactome R-SCE-5656169
type: RelationshipXref
id: R-SCE-5656169
db: reactome

UnificationXref mint MINT-2197646
type: UnificationXref
id: MINT-2197646
db: mint

RelationshipXref go GO 0006268
type: RelationshipXref
id: GO:0006268
db: gene ontology

RelationshipXref go GO 0006265
type: RelationshipXref
id: GO:0006265
db: gene ontology

RelationshipXref go GO 0006264
type: RelationshipXref
id: GO:0006264
db: gene ontology

RelationshipXref intact EBI-7515364 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7515364
db: intact

RelationshipXref go GO 0006261
type: RelationshipXref
id: GO:0006261
db: gene ontology

RelationshipXref go GO 0006260
type: RelationshipXref
id: GO:0006260
db: gene ontology

ExperimentalForm a41fbc54-9ced-44dc-9914-f30bf0c41ce8
type: ExperimentalForm
experimental feature: ModificationFeature b4ec14c8-c603-4534-994d-94b77d93948d 430516
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 441055c7-3f85-4804-b212-5a313f3626ba
type: ExperimentalForm
experimental feature: ModificationFeature c619e4a9-fbdf-499c-bb33-e39f69237cc5 431916
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref rcsb pdb 4QLU
type: RelationshipXref
id: 4QLU
db: protein data bank

RelationshipXref rcsb pdb 4QLT
type: RelationshipXref
id: 4QLT
db: protein data bank

RelationshipXref rcsb pdb 4QLS
type: RelationshipXref
id: 4QLS
db: protein data bank

RelationshipXref rcsb pdb 4QLQ
type: RelationshipXref
id: 4QLQ
db: protein data bank

RelationshipXref rcsb pdb 1UN0
type: RelationshipXref
id: 1UN0
db: protein data bank

RelationshipXref intact EBI-7540983 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7540983
db: intact

RelationshipXref go GO 2000219
type: RelationshipXref
id: GO:2000219
db: gene ontology

RelationshipXref go GO 2000217
type: RelationshipXref
id: GO:2000217
db: gene ontology

RelationshipXref intact EBI-16073 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-16073
db: intact

Evidence 65220499-8cf9-4323-9dd0-c53863d416ee IM-15332-2747 432061 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref dip DIP-5153N
type: RelationshipXref
id: DIP-5153N
db: database of interacting proteins

spt16_yeast
type: Protein
evidence: Evidence 8e7da279-e633-45db-b8e1-f2253c1c71fb p 431074
entity reference: P32558
name: FACT complex subunit SPT16
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 2YHX
type: RelationshipXref
id: 2YHX
db: protein data bank

RelationshipXref interpro IPR033901
type: RelationshipXref
id: IPR033901
db: interpro

ExperimentalForm 0f6324e2-c764-4f53-984b-e469d15d9947
type: ExperimentalForm
experimental feature: ModificationFeature a2ec1952-0b14-457b-8b68-762452958e53 430916
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref reactome R-SCE-5668541
type: RelationshipXref
id: R-SCE-5668541
db: reactome

RelationshipXref imex IM-15332-11260 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-11260
db: imex

ExperimentalForm 2c5cd4e2-3513-4a94-a8b0-8fee4db51d9b
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpb9_yeast
type: Protein
evidence: Evidence 11d4022e-a6fc-4396-be93-70fa644c5407 p 432495
entity reference: P27999
name: DNA-directed RNA polymerase II subunit RPB9
comment: psi-mi participant
data source: intact

RelationshipXref dip DIP-5152N
type: RelationshipXref
id: DIP-5152N
db: database of interacting proteins

RelationshipXref uniprotkb D6VRJ4 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VRJ4
db: uniprot knowledgebase

rpb9_yeast
type: Protein
evidence: Evidence e228a694-9736-4ab5-9036-02840e72616a p 432502
entity reference: P27999
name: DNA-directed RNA polymerase II subunit RPB9
comment: psi-mi participant
data source: intact

Evidence 12735dd7-e86e-411c-bb3a-8d5efafde0f7 IM-15332-4386 431257 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm f316071c-bb2c-4e67-a506-03c75e7a2ee8
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref imex IM-15332-4762 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-4762
db: imex

ExperimentalForm b38680d7-b8cb-4ad9-a4fb-4ddc10d7bd19
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 9db9a0fa-72ed-4522-a01f-2761d24abe10
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref imex IM-15332-5601 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5601
db: imex

RelationshipXref imex IM-15332-11247 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-11247
db: imex

ExperimentalForm 2ff91f2b-8a17-4968-b7c5-7d3de4dc509d
type: ExperimentalForm
experimental feature: ModificationFeature 1b1d2684-8314-4236-b3a7-c60f8f0018a7 431895
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ret2-sec27-5
type: MolecularInteraction
xref: UnificationXref mint MINT-2196366
xref: RelationshipXref imex IM-15332-2343 imex-primary
xref: RelationshipXref intact EBI-7516343 identity
evidence: Evidence 4801a3b9-bf28-4119-9433-dbd66d1cb748 IM-15332-2343 430637 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 0.133219679961228
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P43621 identity 1529029541723
participant: Protein uniprotkb P41811 identity 1529029541722

RelationshipXref go GO 0040020
type: RelationshipXref
id: GO:0040020
db: gene ontology

ExperimentalForm bde950dc-6f64-44bf-b87d-e91e9420b212
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref mint MINT-2207690
type: UnificationXref
id: MINT-2207690
db: mint

RelationshipXref reactome R-SCE-114604
type: RelationshipXref
id: R-SCE-114604
db: reactome

Evidence f5ad091d-ff54-4698-b949-cc84ce795275 IM-15332-12497 433377 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref uniprotkb D6VY42 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VY42
db: uniprot knowledgebase

ExperimentalForm 85b6a12b-53af-4e7d-88a9-ba9cf54784f4
type: ExperimentalForm
experimental feature: ModificationFeature 7117559c-d915-4723-b659-2aa6387ec557 433316
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 2037e156-f53b-4e53-a16a-d53426bfdcce
type: ExperimentalForm
experimental feature: ModificationFeature ec9837c2-0eda-43a5-83b8-9e6773302c9a 432452
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

copa_yeast
type: Protein
evidence: Evidence 7f74b88e-ba39-42a0-ab7b-3cd1c8b7be6b p 430584
entity reference: copa_yeast
name: Coatomer subunit alpha
comment: psi-mi participant
data source: intact

ExperimentalForm b07cf064-46ae-4d68-a847-a69ff73f7748
type: ExperimentalForm
experimental feature: ModificationFeature ada08283-c5c7-4a6a-a695-e1269d372173 431108
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref reactome R-SCE-5689901
type: RelationshipXref
id: R-SCE-5689901
db: reactome

UnificationXref mint MINT-2205096
type: UnificationXref
id: MINT-2205096
db: mint

RelationshipXref intact EBI-7524572 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7524572
db: intact

RelationshipXref intact EBI-7525112 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7525112
db: intact

RelationshipXref go GO 0035556
type: RelationshipXref
id: GO:0035556
db: gene ontology

RelationshipXref uniprotkb P0CX25 see-also
type: RelationshipXref
relationship type: MI:0361
id: P0CX25
db: uniprot knowledgebase

rgr1-med6-1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-8015 imex-primary
xref: UnificationXref mint MINT-2198024
xref: RelationshipXref intact EBI-7518346 identity
evidence: Evidence 72f21e97-7dbc-48d0-b501-8f7869726e96 IM-15332-8015 431005 430156
interaction type: physical association
comment: author-confidence:z-score: 3.66064224298134
comment: comment:mint
comment: author-confidence:reliability score: 0.681
data source: intact
participant: Protein uniprotkb P19263 identity 1529029541906
participant: Protein uniprotkb P38782 identity 1529029541907

UnificationXref mint MINT-2207672
type: UnificationXref
id: MINT-2207672
db: mint

ExperimentalForm 8efb5bec-a18d-4f19-b2f8-a7341294f7e7
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

Evidence cb1af323-4754-4117-b1d0-4e3ea51cb927 IM-15332-9611 432181 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref mint MINT-2196996
type: UnificationXref
id: MINT-2196996
db: mint

ExperimentalForm 6ccc7bec-8a99-4cd5-9331-878e3f013e8e
type: ExperimentalForm
experimental feature: ModificationFeature 5e42bfb5-49d7-4c8b-82d8-036f03d9a0ac 432012
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref reactome R-SCE-5696395
type: RelationshipXref
id: R-SCE-5696395
db: reactome

RelationshipXref go GO 0005816
type: RelationshipXref
id: GO:0005816
db: gene ontology

RelationshipXref rcsb pdb 3MKQ
type: RelationshipXref
id: 3MKQ
db: protein data bank

RelationshipXref go GO 0034198
type: RelationshipXref
id: GO:0034198
db: gene ontology

RelationshipXref rcsb pdb 2YNP
type: RelationshipXref
id: 2YNP
db: protein data bank

RelationshipXref intact EBI-7523109 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7523109
db: intact

rpa43_yeast
type: Protein
evidence: Evidence 18c14cb1-cd52-424e-8b0b-8b753f51db53 p 431946
entity reference: P46669
name: DNA-directed RNA polymerase I subunit RPA43
comment: psi-mi participant
data source: intact

RelationshipXref interpro IPR031157
type: RelationshipXref
id: IPR031157
db: interpro

UnificationXref mint MINT-2200526
type: UnificationXref
id: MINT-2200526
db: mint

UnificationXref mint MINT-2207654
type: UnificationXref
id: MINT-2207654
db: mint

RelationshipXref sgd S000000098
type: RelationshipXref
id: S000000098
db: sgd

RelationshipXref intact EBI-7539995 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7539995
db: intact

RelationshipXref imex IM-15332-7652 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-7652
db: imex

ExperimentalForm 1f28ebb4-3c0c-4c17-bcd6-05804503c3c4
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref interpro IPR000629
type: RelationshipXref
id: IPR000629
db: interpro

UnificationXref mint MINT-2196978
type: UnificationXref
id: MINT-2196978
db: mint

ExperimentalForm 020478dd-b34c-463d-b0a8-3cebcc79f417
type: ExperimentalForm
experimental feature: ModificationFeature 01f1dbdb-9a83-4689-9cdd-580b7e9b4198 432184
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref reactome R-SCE-8854050
type: RelationshipXref
id: R-SCE-8854050
db: reactome

rpa190-rpa43-4
type: MolecularInteraction
xref: UnificationXref mint MINT-2201498
xref: RelationshipXref intact EBI-7523413 identity
xref: RelationshipXref imex IM-15332-12877 imex-primary
evidence: Evidence 1c0bd9a8-eb59-493e-81dd-87498a2e8fcb IM-15332-12877 431777 430156
interaction type: physical association
comment: author-confidence:z-score: 1.4599339011504
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: rpa1_yeast
participant: rpa43_yeast

Evidence 0cfb7f86-3e1f-4988-b393-caa5fdb8f2c4 IM-15332-12486 432221 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref rcsb pdb 1F60
type: RelationshipXref
id: 1F60
db: protein data bank

ExperimentalForm b8592aa2-91fe-4f9b-89ee-b7dcfbd88850
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref mint MINT-2196960
type: UnificationXref
id: MINT-2196960
db: mint

Evidence b372ffa8-5024-4ca0-b0fe-09d0a9ff667d IM-15332-11650 433717 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

Evidence 190f063c-3353-4a2a-b727-64ef3fa35cfb IM-15332-9207 432089 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

Evidence 7af998f2-12aa-4a20-890d-4f59aae14b8c IM-15332-12872 431233 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref dip DIP-4565N
type: RelationshipXref
id: DIP-4565N
db: database of interacting proteins

UnificationXref mint MINT-2207636
type: UnificationXref
id: MINT-2207636
db: mint

RelationshipXref refseq NP 014190 1
type: RelationshipXref
id: NP_014190.1
db: refseq

RelationshipXref intact EBI-7536184 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7536184
db: intact

ExperimentalForm 62809aad-e565-4759-9be7-e8b685d19fcf
type: ExperimentalForm
experimental feature: ModificationFeature 46b58010-c6ab-4ccd-adef-857165d7610b 432587
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 5c95f7e2-5c73-4def-95c1-98b5d4edec70
type: ExperimentalForm
experimental feature: ModificationFeature 8fb7949a-f398-4a7a-b6ab-c38bc8020041 431091
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref rcsb pdb 4QBY
type: RelationshipXref
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db: protein data bank

RelationshipXref imex IM-15332-12874 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12874
db: imex

RelationshipXref interpro IPR000648
type: RelationshipXref
id: IPR000648
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Evidence 94fec744-859e-4b56-b89c-1d724d567099 IM-15332-1222 433429 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref mint MINT-2206285
type: UnificationXref
id: MINT-2206285
db: mint

ret2-sec27-9
type: MolecularInteraction
xref: UnificationXref mint MINT-2196474
xref: RelationshipXref imex IM-15332-1207 imex-primary
xref: RelationshipXref intact EBI-7516504 identity
evidence: Evidence 282ead40-4649-4c0a-8e42-a6a642b53d3c IM-15332-1207 430661 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.99
comment: comment:homomint
comment: comment:mint
comment: author-confidence:z-score: 5.98634211221213
data source: intact
participant: Protein uniprotkb P43621 identity 1529029541734
participant: Protein uniprotkb P41811 identity 1529029541735

UnificationXref uniprot knowledgebase Q06142
type: UnificationXref
id: Q06142
db: uniprot knowledgebase

ExperimentalForm 21df5781-d444-4e47-9f42-41a4cb0988a9
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref rcsb pdb 1E9G
type: RelationshipXref
id: 1E9G
db: protein data bank

Evidence 605b54bd-1f2e-4462-ad78-752f3cc04191 IM-15332-9626 433901 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref sgd S000002812
type: RelationshipXref
id: S000002812
db: sgd

RelationshipXref rcsb pdb 6FAI
type: RelationshipXref
id: 6FAI
db: protein data bank

ExperimentalForm a266ecde-7313-4a46-a3eb-f1c86791ae60
type: ExperimentalForm
experimental feature: ModificationFeature 3f3f0b3c-f0fe-4e0d-b195-ff19489998d9 432823
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-3979 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-3979
db: imex

RelationshipXref dip DIP-4429N
type: RelationshipXref
id: DIP-4429N
db: database of interacting proteins

rim1-pfk26
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-12478 imex-primary
xref: RelationshipXref intact EBI-7518647 identity
xref: UnificationXref mint MINT-2198294
evidence: Evidence 9c1ba2ef-58aa-467b-bcb1-1863a5b06833 IM-15332-12478 431065 430156
interaction type: physical association
comment: author-confidence:z-score: 2.63995251500696
comment: author-confidence:reliability score: 0.612
comment: comment:mint
data source: intact
participant: Protein uniprotkb P40433 identity 1529029541937
participant: rim1_yeast

rpa43_yeast
type: Protein
evidence: Evidence 86c6a85d-32fb-4c16-a39f-f5bd3f425b11 p 431867
entity reference: P46669
name: DNA-directed RNA polymerase I subunit RPA43
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2200562
type: UnificationXref
id: MINT-2200562
db: mint

UnificationXref mint MINT-2196942
type: UnificationXref
id: MINT-2196942
db: mint

RelationshipXref intact EBI-7542676 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7542676
db: intact

rpa43_yeast
type: Protein
evidence: Evidence 32de12e4-62da-4182-ab04-c8312348493d p 431855
entity reference: P46669
name: DNA-directed RNA polymerase I subunit RPA43
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2207618
type: UnificationXref
id: MINT-2207618
db: mint

RelationshipXref rcsb pdb 3MG8
type: RelationshipXref
id: 3MG8
db: protein data bank

RelationshipXref rcsb pdb 3MG7
type: RelationshipXref
id: 3MG7
db: protein data bank

RelationshipXref rcsb pdb 3MG6
type: RelationshipXref
id: 3MG6
db: protein data bank

RelationshipXref rcsb pdb 3MG4
type: RelationshipXref
id: 3MG4
db: protein data bank

RelationshipXref intact EBI-7518599 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7518599
db: intact

RelationshipXref rcsb pdb 3MG0
type: RelationshipXref
id: 3MG0
db: protein data bank

RelationshipXref intact EBI-7522962 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7522962
db: intact

ExperimentalForm 572c9b2e-b3d7-4b5c-8024-7ef3863da6ed
type: ExperimentalForm
experimental feature: ModificationFeature dfd766f3-b8e5-425f-8c9f-9a35bd45a58d 431191
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

UnificationXref mint MINT-2201912
type: UnificationXref
id: MINT-2201912
db: mint

UnificationXref mint MINT-2206267
type: UnificationXref
id: MINT-2206267
db: mint

rpa43_yeast
type: Protein
evidence: Evidence 1072b27d-76ed-40b5-8aa9-3d4e2b02345a p 431846
entity reference: P46669
name: DNA-directed RNA polymerase I subunit RPA43
comment: psi-mi participant
data source: intact

rpa43_yeast
type: Protein
evidence: Evidence 724421d4-5990-4b6b-b228-eb2b19e1ea68 p 431843
entity reference: P46669
name: DNA-directed RNA polymerase I subunit RPA43
comment: psi-mi participant
data source: intact

rpa43_yeast
type: Protein
evidence: Evidence 702fbf9f-e48b-4273-afdd-9ea5fa084d91 p 431839
entity reference: P46669
name: DNA-directed RNA polymerase I subunit RPA43
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7541833 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7541833
db: intact

rpa43_yeast
type: Protein
evidence: Evidence b896bad6-bf81-4ea9-9a3f-06401f28399f p 431835
entity reference: P46669
name: DNA-directed RNA polymerase I subunit RPA43
comment: psi-mi participant
data source: intact

rfa1_yeast
type: Protein
evidence: Evidence b2084973-6988-4341-a689-520a78f788aa p 430719
entity reference: P22336
name: Replication factor A protein 1
comment: psi-mi participant
data source: intact

rpb3-rpb2-2
type: MolecularInteraction
xref: UnificationXref mint MINT-2203767
xref: RelationshipXref imex IM-15332-1217 imex-primary
xref: RelationshipXref intact EBI-7527394 identity
evidence: Evidence 3a070b0c-0904-4303-898b-856b5d7f6076 IM-15332-1217 432281 430156
interaction type: physical association
comment: author-confidence:z-score: 4.37706639306202
comment: comment:mint
comment: author-confidence:reliability score: 0.97
data source: intact
participant: Protein uniprotkb P16370 identity 1529029542544
participant: Protein uniprotkb P08518 identity 1529029542545

UnificationXref mint MINT-2207600
type: UnificationXref
id: MINT-2207600
db: mint

RelationshipXref refseq NP 009712 1
type: RelationshipXref
id: NP_009712.1
db: refseq

RelationshipXref imex IM-15332-407 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-407
db: imex

RelationshipXref interpro IPR005990
type: RelationshipXref
id: IPR005990
db: interpro

ExperimentalForm 3a4174f0-9d96-4edc-ab2e-87b03cf6d7ed
type: ExperimentalForm
experimental feature: ModificationFeature 9205efe4-f723-4307-b8b9-1b30d0f3c159 431551
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

atg11_yeast
type: Protein
evidence: Evidence 14900d81-b71d-4bb0-a86b-8fd3b4c6d850 p 433210
entity reference: atg11_yeast
name: Autophagy-related protein 11
comment: psi-mi participant
data source: intact

ExperimentalForm 4940eb3e-7a9d-498e-a80c-705e3790de65
type: ExperimentalForm
experimental feature: ModificationFeature aa1f5728-0afd-48bc-bb06-a1592c154ad7 433876
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref rcsb pdb 2IK7
type: RelationshipXref
id: 2IK7
db: protein data bank

UnificationXref mint MINT-2196924
type: UnificationXref
id: MINT-2196924
db: mint

RelationshipXref rcsb pdb 2IK4
type: RelationshipXref
id: 2IK4
db: protein data bank

ExperimentalForm 7e85bbf0-6199-436c-8de4-f65ba254ad59
type: ExperimentalForm
experimental feature: ModificationFeature ff2abff3-48d2-452c-8ca8-3b5896161191 432903
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref rcsb pdb 2IK2
type: RelationshipXref
id: 2IK2
db: protein data bank

RelationshipXref rcsb pdb 2IK1
type: RelationshipXref
id: 2IK1
db: protein data bank

RelationshipXref rcsb pdb 2IK0
type: RelationshipXref
id: 2IK0
db: protein data bank

RelationshipXref go GO 0004722
type: RelationshipXref
id: GO:0004722
db: gene ontology

rpc19-rpa49
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-9616 imex-primary
xref: UnificationXref mint MINT-2205763
xref: RelationshipXref intact EBI-7532531 identity
evidence: Evidence 5920a9c4-a542-4a48-ba9c-28a0aff3451e IM-15332-9616 432713 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.979
comment: comment:mint
comment: author-confidence:z-score: 9.81087458255009
data source: intact
participant: Protein uniprotkb P28000 identity 1529029542760
participant: Protein uniprotkb Q01080 identity 1529029542761

rpb10-rpc82
type: MolecularInteraction
xref: UnificationXref mint MINT-2202039
xref: RelationshipXref imex IM-15332-2351 imex-primary
xref: RelationshipXref intact EBI-7524221 identity
evidence: Evidence 34db4588-e9b0-418b-876b-e4794d839e26 IM-15332-2351 431897 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.851
comment: comment:mint
comment: author-confidence:z-score: 6.33702350434881
data source: intact
participant: Protein uniprotkb P32349 identity 1529029542352
participant: rpab5_yeast

RelationshipXref imex IM-15332-2758 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-2758
db: imex

rl1_yeast
type: ProteinReference
sequence: MSKITSSQVREHVKELLKYSNETKKRNFLETVELQVGLKNYDPQRDKRFSGSLKLPNCPRPNMSICIFGDAFDVDRAKSCGVDAMSVDDLKKLNKNKKLIKKLSKKYNAFIASEVLIKQVPRLLGPQLSKAGKFPTPVSHNDDLYGKVTDVRSTIKFQLKKVLCLAVAVGNVEMEEDVLVNQILMSVNFFVSLLKKNWQNVGSLVVKSSMGPAFRLY
xref: RelationshipXref cygd YPL220w
xref: RelationshipXref uniprotkb D6VU14 secondary-ac
xref: RelationshipXref rcsb pdb 3O58
xref: RelationshipXref interpro IPR002143
xref: UnificationXref uniprot knowledgebase P53030
xref: RelationshipXref go GO 0003735
xref: RelationshipXref go GO 0006412
xref: RelationshipXref interpro IPR016095
xref: RelationshipXref refseq NP 015104 1
xref: RelationshipXref interpro IPR023674
xref: RelationshipXref interpro IPR023673
xref: RelationshipXref sgd S000003103
xref: RelationshipXref rcsb pdb 3IZS
xref: RelationshipXref go GO 0006396
xref: RelationshipXref go GO 0003723
xref: RelationshipXref rcsb pdb 2NOQ
xref: RelationshipXref cygd YGL135w
xref: RelationshipXref interpro IPR016094
xref: RelationshipXref rcsb pdb 1K5Y
xref: RelationshipXref intact EBI-14442 identity
xref: RelationshipXref sgd S000006141
xref: RelationshipXref rcsb pdb 1S1I
xref: RelationshipXref go GO 0022625
xref: RelationshipXref refseq NP 011380 1
xref: RelationshipXref rcsb pdb 3O5H
organism: http://identifiers.org/taxonomy/559292
name: SSM1B
name: YGL135W
name: SSM2
name: YPL220W
name: SSM1A
name: G2834
name: L10a
name: 60S ribosomal protein L1
name: RPL1B
name: RPL1A
name: SSM1

RelationshipXref intact EBI-7531996 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7531996
db: intact

ExperimentalForm 643224a5-cc27-4564-950d-9243058b6e83
type: ExperimentalForm
experimental feature: ModificationFeature a903fe4d-ccf0-442b-ba6d-956a2fdc6528 433603
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

UnificationXref mint MINT-2206249
type: UnificationXref
id: MINT-2206249
db: mint

ExperimentalForm 017ea2d3-718d-4fa6-b9f3-ef174022b234
type: ExperimentalForm
experimental feature: ModificationFeature 056f172d-351d-48fc-81cc-61c2d46f64f7 433827
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 6a1d55a5-ee33-44c7-a25b-b9547c4f6c1d
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-15927 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-15927
db: intact

RelationshipXref go GO 0005851
type: RelationshipXref
id: GO:0005851
db: gene ontology

Evidence 902a3495-2108-475b-bcf9-f6173ab5da53 IM-15332-10026 431765 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpa43_yeast
type: Protein
evidence: Evidence 432c7d1f-6c0d-4676-8c04-40e57d9a67e1 p 431794
entity reference: P46669
name: DNA-directed RNA polymerase I subunit RPA43
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 1ENW
type: RelationshipXref
id: 1ENW
db: protein data bank

Evidence 691bc7ae-a4f5-4b0f-92ab-9af69ec3918c IM-15332-4794 433413 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref rcsb pdb 1EO0
type: RelationshipXref
id: 1EO0
db: protein data bank

rir1_yeast
type: Protein
evidence: Evidence 769e7ebf-75cc-40e6-930a-75c0fc3d0673 p 431410
entity reference: P21524
name: Ribonucleoside-diphosphate reductase large chain 1
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2196906
type: UnificationXref
id: MINT-2196906
db: mint

UnificationXref mint MINT-2206231
type: UnificationXref
id: MINT-2206231
db: mint

RelationshipXref intact EBI-7532594 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7532594
db: intact

rfa2_yeast
type: Protein
evidence: Evidence 9133f966-19ba-4d0f-8655-4f7ae1488ee8 p 430810
entity reference: P26754
name: Replication factor A protein 2
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 2IHP
type: RelationshipXref
id: 2IHP
db: protein data bank

RelationshipXref uniprotkb D6VU14 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VU14
db: uniprot knowledgebase

RelationshipXref imex IM-15332-10444 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-10444
db: imex

RelationshipXref intact EBI-7524540 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7524540
db: intact

RelationshipXref mint P15108
type: RelationshipXref
id: P15108
db: mint

Evidence 258ba52a-33c3-4f14-b60a-ae4cced60098 IM-15332-8020 431561 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref mint MINT-2195555
type: UnificationXref
id: MINT-2195555
db: mint

Evidence c44530f3-ada6-4681-afa1-225b8c91e799 IM-15332-6785 432821 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref go GO 0042797
type: RelationshipXref
id: GO:0042797
db: gene ontology

RelationshipXref imex IM-15332-11248 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-11248
db: imex

ExperimentalForm 7a5a5318-38d4-455e-b500-6a084a69fd6b
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rir1_yeast
type: Protein
evidence: Evidence 7d0f9511-2ba1-4c61-9239-06fdd0564e08 p 431426
entity reference: P21524
name: Ribonucleoside-diphosphate reductase large chain 1
comment: psi-mi participant
data source: intact

RelationshipXref go GO 0042790
type: RelationshipXref
id: GO:0042790
db: gene ontology

RelationshipXref intact EBI-7543168 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7543168
db: intact

ExperimentalForm e8723173-7ed8-4b75-bbad-940502144f7d
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref sgd S000002687
type: RelationshipXref
id: S000002687
db: sgd

RelationshipXref mint P40016
type: RelationshipXref
id: P40016
db: mint

physical association
type: InteractionVocabulary
xref: UnificationXref molecular interactions ontology MI 0915

ExperimentalForm 8b785d0b-5282-47af-a140-3e3c4fa90b4c
type: ExperimentalForm
experimental feature: ModificationFeature fb56294d-cfdd-484e-89cc-a3c3c0d4f623 430572
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7539365 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7539365
db: intact

rpc3_yeast
type: ProteinReference
sequence: MDELLGEALSAENQTGESTVESEKLVTPEDVMTISSLEQRTLNPDLFLYKELVKAHLGERAASVIGMLVALGRLSVRELVEKIDGMDVDSVKTTLVSLTQLRCVKYLQETAISGKKTTYYYYNEEGIHILLYSGLIIDEIITQMRVNDEEEHKQLVAEIVQNVISLGSLTVEDYLSSVTSDSMKYTISSLFVQLCEMGYLIQISKLHYTPIEDLWQFLYEKHYKNIPRNSPLSDLKKRSQAKMNAKTDFAKIINKPNELSQILTVDPKTSLRIVKPTVSLTINLDRFMKGRRSKQLINLAKTRVGSVTAQVYKIALRLTEQKSPKIRDPLTQTGLLQDLEEAKSFQDEAELVEEKTPGLTFNAIDLARHLPAELDLRGSLLSRKPSDNKKRSGSNAAASLPSKKLKTEDGFVIPALPAAVSKSLQESGDTQEEDEEEEDLDADTEDPHSASLINSHLKILASSNFPFLNETKPGVYYVPYSKLMPVLKSSVYEYVIASTLGPSAMRLSRCIRDNKLVSEKIINSTALMKEKDIRSTLASLIRYNSVEIQEVPRTADRSASRAVFLFRCKETHSYNFMRQNLEWNMANLLFKKEKLKQENSTLLKKANRDDVKGRENELLLPSELNQLKMVNERELNVFARLSRLLSLWEVFQMA
xref: RelationshipXref go GO 0042797
xref: RelationshipXref refseq NP 015516 1
xref: RelationshipXref interpro IPR013197
xref: RelationshipXref go GO 0003899
xref: RelationshipXref uniprotkb D6W4J0 secondary-ac
xref: RelationshipXref mint P32349
xref: RelationshipXref go GO 0005654
xref: RelationshipXref rcsb pdb 5FJA
xref: RelationshipXref rcsb pdb 6F44
xref: RelationshipXref rcsb pdb 6F42
xref: RelationshipXref rcsb pdb 6F41
xref: RelationshipXref rcsb pdb 6F40
xref: RelationshipXref rcsb pdb 5FJ8
xref: RelationshipXref sgd S000006394
xref: RelationshipXref dip DIP-934N
xref: RelationshipXref interpro IPR036388
xref: RelationshipXref intact EBI-15821 identity
xref: RelationshipXref rcsb pdb 6EU3
xref: RelationshipXref rcsb pdb 5FJ9
xref: RelationshipXref rcsb pdb 6EU1
xref: RelationshipXref rcsb pdb 6EU0
xref: RelationshipXref go GO 0003677
xref: RelationshipXref interpro IPR008806
xref: UnificationXref uniprot knowledgebase P32349
xref: RelationshipXref go GO 0006386
xref: RelationshipXref go GO 0005666
xref: RelationshipXref uniprotkb Q06591 secondary-ac
xref: RelationshipXref go GO 0005737
xref: RelationshipXref rcsb pdb 6EU2
organism: http://identifiers.org/taxonomy/559292
name: C82
name: DNA-directed III 74 kDa polypeptide
name: YPR190C
name: RPC3
name: DNA-directed RNA polymerase III subunit RPC3
name: P9677.11
name: RPC82

rir1_yeast
type: Protein
evidence: Evidence f0e6cd5c-1f13-4aac-8a56-e20e8adeb900 p 431435
entity reference: P21524
name: Ribonucleoside-diphosphate reductase large chain 1
comment: psi-mi participant
data source: intact

rfa2_yeast
type: Protein
evidence: Evidence 04c58f51-1a93-4b63-bd60-898313819737 p 430822
entity reference: P26754
name: Replication factor A protein 2
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2206213
type: UnificationXref
id: MINT-2206213
db: mint

ExperimentalForm fd251c8f-153e-4d33-ace4-64fb600b216b
type: ExperimentalForm
experimental feature: ModificationFeature 9c284445-e497-40b1-b4ee-3a4c6546e978 431680
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7525179 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7525179
db: intact

RelationshipXref dip DIP-2357N
type: RelationshipXref
id: DIP-2357N
db: database of interacting proteins

RelationshipXref rcsb pdb 5U5Q
type: RelationshipXref
id: 5U5Q
db: protein data bank

UnificationXref mint MINT-2195537
type: UnificationXref
id: MINT-2195537
db: mint

ret2-sec26-3
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-8800 imex-primary
xref: UnificationXref mint MINT-2196024
xref: RelationshipXref intact EBI-7515909 identity
evidence: Evidence ee8c2062-62a5-49c6-be4d-0514b7c207b6 IM-15332-8800 430561 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: -0.0563613663006583
comment: author-confidence:reliability score: 0.976
comment: comment:mint
data source: intact
participant: Protein uniprotkb P41810 identity 1529029541684
participant: Protein uniprotkb P43621 identity 1529029541685

rir2_yeast
type: Protein
evidence: Evidence 7b8105b8-ed55-4067-a3fb-3b8c901181c4 p 431476
entity reference: P09938
name: Ribonucleoside-diphosphate reductase small chain 1
comment: psi-mi participant
data source: intact

rpb10-pre5
type: MolecularInteraction
xref: RelationshipXref intact EBI-7525799 identity
xref: UnificationXref mint MINT-2203047
xref: RelationshipXref imex IM-15332-6380 imex-primary
evidence: Evidence 9caab5fc-4743-407d-ad6f-0957c01e3495 IM-15332-6380 432121 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.379
comment: author-confidence:z-score: 4.12564841481883
comment: comment:mint
data source: intact
participant: psa6_yeast
participant: rpab5_yeast

ExperimentalForm 98b7397d-0834-4cc1-9600-c641c98b1754
type: ExperimentalForm
experimental feature: ModificationFeature 88cb461c-ee2a-4f29-b005-81fcb87db481 430771
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm af7067e7-4de4-40e5-af4d-23d250f68e7d
type: ExperimentalForm
experimental feature: ModificationFeature 7aad1cb6-16a1-4c16-97c7-9debf6a238b3 430919
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm eecf4448-9704-4912-9971-fa54b50bc69f
type: ExperimentalForm
experimental feature: ModificationFeature f89c9381-1d2e-4fcb-a1a1-ed6328f02df1 431335
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-11632 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-11632
db: imex

RelationshipXref interpro IPR004591
type: RelationshipXref
id: IPR004591
db: interpro

RelationshipXref rcsb pdb 5U4P
type: RelationshipXref
id: 5U4P
db: protein data bank

RelationshipXref interpro IPR005937
type: RelationshipXref
id: IPR005937
db: interpro

ExperimentalForm c84785e5-3dba-49c9-b659-f084ebf5b2d1
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 427bf66e-e602-41d1-acfd-62b4714d0118
type: ExperimentalForm
experimental feature: ModificationFeature 9a93b6ad-59a2-4338-8e44-32358d77a719 430436
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm d1436470-4443-4af4-8620-833d86d51457
type: ExperimentalForm
experimental feature: ModificationFeature c68e73f0-e1e0-4e09-9927-c42452c09cdb 432363
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref sgd S000002898
type: RelationshipXref
id: S000002898
db: sgd

RelationshipXref imex IM-15332-8012 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-8012
db: imex

RelationshipXref intact EBI-7530375 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7530375
db: intact

RelationshipXref rcsb pdb 5BOU
type: RelationshipXref
id: 5BOU
db: protein data bank

UnificationXref mint MINT-2195519
type: UnificationXref
id: MINT-2195519
db: mint

RelationshipXref mint P39960
type: RelationshipXref
id: P39960
db: mint

rpc9_yeast
type: Protein
evidence: Evidence 2dafd429-776e-4e9e-8d95-8fd0156c3d4e p 432698
entity reference: rpc9_yeast
name: DNA-directed RNA polymerase III subunit RPC9
comment: psi-mi participant
data source: intact

RelationshipXref sgd S000002646
type: RelationshipXref
id: S000002646
db: sgd

RelationshipXref intact EBI-8484 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-8484
db: intact

RelationshipXref imex IM-15332-11250 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-11250
db: imex

RelationshipXref go GO 0005886
type: RelationshipXref
id: GO:0005886
db: gene ontology

rpac2_yeast
type: Protein
evidence: Evidence 4e9bc9d5-faf8-418e-9b45-43325f1bed0e p 432690
entity reference: P28000
name: DNA-directed RNA polymerases I and III subunit RPAC2
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-7207 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-7207
db: imex

Evidence 50b5fb52-f56e-4bf4-906b-1530f7b08a15 IM-15332-11649 433653 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref mint MINT-2195501
type: UnificationXref
id: MINT-2195501
db: mint

RelationshipXref sgd S000001297
type: RelationshipXref
id: S000001297
db: sgd

RelationshipXref intact EBI-7518728 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7518728
db: intact

ExperimentalForm 16cb978f-8077-426b-a3f6-3167fe45596a
type: ExperimentalForm
experimental feature: ModificationFeature 6f18dc3c-aa67-439c-b988-41177624e834 433375
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpc9_yeast
type: Protein
evidence: Evidence 38421fa2-a8e1-48bc-83aa-18f37377d67a p 432682
entity reference: rpc9_yeast
name: DNA-directed RNA polymerase III subunit RPC9
comment: psi-mi participant
data source: intact

rpc9_yeast
type: Protein
evidence: Evidence 58c3669f-7b5c-4f2d-8932-ec769e442f4c p 432678
entity reference: rpc9_yeast
name: DNA-directed RNA polymerase III subunit RPC9
comment: psi-mi participant
data source: intact

rpc9_yeast
type: Protein
evidence: Evidence 763eaa53-38e7-4fec-907f-43b351acb142 p 432675
entity reference: rpc9_yeast
name: DNA-directed RNA polymerase III subunit RPC9
comment: psi-mi participant
data source: intact

rpb10-rpo31
type: MolecularInteraction
xref: RelationshipXref intact EBI-7525514 identity
xref: UnificationXref mint MINT-2202831
xref: RelationshipXref imex IM-15332-2354 imex-primary
evidence: Evidence 57734b42-dc2d-46fb-ac6c-77dc30c4618a IM-15332-2354 432073 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 2.25588061434637
comment: author-confidence:reliability score: 0.919
comment: comment:mint
data source: intact
participant: Protein uniprotkb P04051 identity 1529029542441
participant: rpab5_yeast

rpac2_yeast
type: Protein
evidence: Evidence f88de5c4-6f64-481e-92ec-52edda8ffb05 p 432710
entity reference: P28000
name: DNA-directed RNA polymerases I and III subunit RPAC2
comment: psi-mi participant
data source: intact

rpab1_yeast
type: ProteinReference
sequence: MDQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
xref: RelationshipXref rcsb pdb 3PO3
xref: RelationshipXref rcsb pdb 3S14
xref: RelationshipXref rcsb pdb 3HOZ
xref: RelationshipXref rcsb pdb 3HOY
xref: RelationshipXref rcsb pdb 3HOX
xref: RelationshipXref rcsb pdb 3HOW
xref: RelationshipXref rcsb pdb 3QT1
xref: RelationshipXref rcsb pdb 3HOU
xref: RelationshipXref rcsb pdb 1TWA
xref: RelationshipXref reactome R-SCE-72086
xref: RelationshipXref rcsb pdb 5N5Z
xref: RelationshipXref rcsb pdb 5N5Y
xref: RelationshipXref rcsb pdb 3GTQ
xref: RelationshipXref rcsb pdb 3GTP
xref: RelationshipXref rcsb pdb 3GTO
xref: RelationshipXref rcsb pdb 3GTM
xref: RelationshipXref rcsb pdb 3GTL
xref: RelationshipXref rcsb pdb 3GTK
xref: RelationshipXref rcsb pdb 3GTJ
xref: RelationshipXref rcsb pdb 5N60
xref: RelationshipXref rcsb pdb 3M4O
xref: RelationshipXref go GO 0005666
xref: RelationshipXref rcsb pdb 5IP9
xref: RelationshipXref rcsb pdb 5IP7
xref: RelationshipXref go GO 0005736
xref: RelationshipXref rcsb pdb 6BQF
xref: RelationshipXref rcsb pdb 3M3Y
xref: RelationshipXref rcsb pdb 4Y7N
xref: RelationshipXref rcsb pdb 1K83
xref: RelationshipXref rcsb pdb 3H3V
xref: RelationshipXref rcsb pdb 4V1M
xref: RelationshipXref rcsb pdb 5VVS
xref: RelationshipXref rcsb pdb 5VVR
xref: RelationshipXref rcsb pdb 3S2H
xref: RelationshipXref go GO 0006383
xref: RelationshipXref rcsb pdb 5C3E
xref: RelationshipXref go GO 0005665
xref: RelationshipXref reactome R-SCE-674695
xref: RelationshipXref reactome R-SCE-75953
xref: RelationshipXref rcsb pdb 2E2I
xref: RelationshipXref go GO 0042254
xref: RelationshipXref rcsb pdb 1WCM
xref: RelationshipXref reactome R-SCE-6796648
xref: RelationshipXref reactome R-SCE-77075
xref: RelationshipXref rcsb pdb 4A3M
xref: RelationshipXref rcsb pdb 4A3L
xref: RelationshipXref rcsb pdb 4A3K
xref: RelationshipXref rcsb pdb 4A3J
xref: RelationshipXref rcsb pdb 4A3I
xref: RelationshipXref go GO 0005654
xref: RelationshipXref rcsb pdb 5W65
xref: RelationshipXref rcsb pdb 5W64
xref: RelationshipXref rcsb pdb 4A3E
xref: RelationshipXref rcsb pdb 1DZF
xref: RelationshipXref rcsb pdb 4A3C
xref: RelationshipXref rcsb pdb 4A3B
xref: RelationshipXref rcsb pdb 4Y52
xref: RelationshipXref rcsb pdb 5W66
xref: RelationshipXref rcsb pdb 6BLO
xref: RelationshipXref rcsb pdb 5W5Y
xref: RelationshipXref rcsb pdb 6BM4
xref: RelationshipXref rcsb pdb 6BLP
xref: RelationshipXref rcsb pdb 5M5Y
xref: RelationshipXref rcsb pdb 5M5X
xref: RelationshipXref rcsb pdb 5M5W
xref: RelationshipXref rcsb pdb 6BM2
xref: RelationshipXref reactome R-SCE-73776
xref: RelationshipXref rcsb pdb 5M64
xref: RelationshipXref rcsb pdb 1Y77
xref: RelationshipXref rcsb pdb 4YM7
xref: RelationshipXref rcsb pdb 2R7Z
xref: RelationshipXref rcsb pdb 5FYW
xref: RelationshipXref rcsb pdb 5FZ5
xref: RelationshipXref rcsb pdb 2E2H
xref: RelationshipXref reactome R-SCE-73762
xref: RelationshipXref rcsb pdb 2VUM
xref: RelationshipXref go GO 0006386
xref: RelationshipXref rcsb pdb 6EU3

rpab2_yeast
type: ProteinReference
sequence: MSDYEEAFNDGNENFEDFDVEHFSDEETYEEKPQFKDGETTDANGKTIVTGGNGPEDFQQHEQIRRKTLKEKAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL
xref: RelationshipXref rcsb pdb 3S2H
xref: RelationshipXref rcsb pdb 3HOZ
xref: RelationshipXref rcsb pdb 3HOY
xref: RelationshipXref rcsb pdb 3HOX
xref: RelationshipXref rcsb pdb 3HOW
xref: RelationshipXref rcsb pdb 3QT1
xref: RelationshipXref rcsb pdb 3HOU
xref: RelationshipXref rcsb pdb 1TWA
xref: RelationshipXref reactome R-SCE-72086
xref: RelationshipXref rcsb pdb 5N5Z
xref: RelationshipXref rcsb pdb 5N5Y
xref: RelationshipXref rcsb pdb 3GTQ
xref: RelationshipXref rcsb pdb 3GTP
xref: RelationshipXref rcsb pdb 3GTO
xref: RelationshipXref rcsb pdb 3GTM
xref: RelationshipXref rcsb pdb 3GTL
xref: RelationshipXref rcsb pdb 3GTK
xref: RelationshipXref rcsb pdb 3GTJ
xref: RelationshipXref rcsb pdb 5N60
xref: RelationshipXref rcsb pdb 4A93
xref: RelationshipXref rcsb pdb 3M4O
xref: RelationshipXref rcsb pdb 4BBS
xref: RelationshipXref rcsb pdb 5IP9
xref: RelationshipXref go GO 0005737
xref: RelationshipXref go GO 0005736
xref: RelationshipXref rcsb pdb 6BQF
xref: RelationshipXref dip DIP-2194N
xref: RelationshipXref rcsb pdb 3M3Y
xref: RelationshipXref rcsb pdb 4Y7N
xref: RelationshipXref interpro IPR006111
xref: RelationshipXref interpro IPR006110
xref: RelationshipXref rcsb pdb 1K83
xref: RelationshipXref rcsb pdb 3H3V
xref: RelationshipXref rcsb pdb 4V1M
xref: RelationshipXref rcsb pdb 5VVS
xref: RelationshipXref rcsb pdb 5VVR
xref: RelationshipXref go GO 0006383
xref: RelationshipXref go GO 0005666
xref: RelationshipXref go GO 0005665
xref: RelationshipXref reactome R-SCE-674695
xref: RelationshipXref reactome R-SCE-75953
xref: RelationshipXref rcsb pdb 2E2I
xref: RelationshipXref go GO 0042254
xref: RelationshipXref rcsb pdb 5IP7
xref: RelationshipXref reactome R-SCE-6796648
xref: RelationshipXref reactome R-SCE-77075
xref: RelationshipXref rcsb pdb 4A3M
xref: RelationshipXref rcsb pdb 4A3L
xref: RelationshipXref rcsb pdb 4A3K
xref: RelationshipXref rcsb pdb 4A3J
xref: RelationshipXref rcsb pdb 4A3I
xref: RelationshipXref go GO 0005654
xref: RelationshipXref rcsb pdb 5W65
xref: RelationshipXref rcsb pdb 5W64
xref: RelationshipXref rcsb pdb 4A3E
xref: RelationshipXref rcsb pdb 4A3D
xref: RelationshipXref rcsb pdb 4A3C
xref: RelationshipXref rcsb pdb 4A3B
xref: RelationshipXref rcsb pdb 4Y52
xref: RelationshipXref rcsb pdb 5W66
xref: RelationshipXref rcsb pdb 6BLO
xref: RelationshipXref interpro IPR028363
xref: RelationshipXref rcsb pdb 6BM4
xref: RelationshipXref rcsb pdb 6BLP
xref: RelationshipXref rcsb pdb 5M5Y
xref: RelationshipXref rcsb pdb 5M5X
xref: RelationshipXref rcsb pdb 5M5W
xref: RelationshipXref rcsb pdb 6BM2
xref: RelationshipXref reactome R-SCE-73776
xref: RelationshipXref rcsb pdb 5M64
xref: RelationshipXref rcsb pdb 1Y77
xref: RelationshipXref rcsb pdb 4YM7
xref: RelationshipXref rcsb pdb 5W5Y
xref: RelationshipXref rcsb pdb 2R7Z
xref: RelationshipXref rcsb pdb 5FYW
xref: RelationshipXref rcsb pdb 5FZ5
xref: RelationshipXref rcsb pdb 2E2H
xref: RelationshipXref reactome R-SCE-73762

RelationshipXref intact EBI-7530538 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7530538
db: intact

RelationshipXref go GO 0006412
type: RelationshipXref
id: GO:0006412
db: gene ontology

RelationshipXref go GO 0006414
type: RelationshipXref
id: GO:0006414
db: gene ontology

RelationshipXref imex IM-15332-9200 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-9200
db: imex

Evidence 1bf6aa84-db0b-4eac-ba91-7246bcdaafd8 IM-15332-3991 432577 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref sgd S000001283
type: RelationshipXref
id: S000001283
db: sgd

UnificationXref uniprot knowledgebase P20433
type: UnificationXref
id: P20433
db: uniprot knowledgebase

rpc9_yeast
type: Protein
evidence: Evidence 5a1646cd-49fe-4168-95ea-21546639b0ae p 432666
entity reference: rpc9_yeast
name: DNA-directed RNA polymerase III subunit RPC9
comment: psi-mi participant
data source: intact

rpc9_yeast
type: Protein
evidence: Evidence 984f95ab-c661-4834-9289-76b25364c54d p 432662
entity reference: rpc9_yeast
name: DNA-directed RNA polymerase III subunit RPC9
comment: psi-mi participant
data source: intact

rpc9_yeast
type: Protein
evidence: Evidence 4bc5a540-403a-46cc-bb58-86fe5d780abd p 432658
entity reference: rpc9_yeast
name: DNA-directed RNA polymerase III subunit RPC9
comment: psi-mi participant
data source: intact

rpc9_yeast
type: Protein
evidence: Evidence f1632a7c-f79d-4582-acdd-5b8824319aa1 p 432654
entity reference: rpc9_yeast
name: DNA-directed RNA polymerase III subunit RPC9
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7543638 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7543638
db: intact

RelationshipXref refseq NP 014407 3
type: RelationshipXref
id: NP_014407.3
db: refseq

rpb10-rpo21-1
type: MolecularInteraction
xref: UnificationXref mint MINT-2202615
xref: RelationshipXref intact EBI-7525226 identity
xref: RelationshipXref imex IM-15332-6378 imex-primary
evidence: Evidence c99c346e-6abf-44bb-90c7-53df973a93a9 IM-15332-6378 432025 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 2.56343717930309
comment: comment:mint
comment: author-confidence:reliability score: 0.968
data source: intact
participant: Protein uniprotkb P04050 identity 1529029542416
participant: rpab5_yeast

RelationshipXref refseq NP 014069 1
type: RelationshipXref
id: NP_014069.1
db: refseq

RelationshipXref interpro IPR033898
type: RelationshipXref
id: IPR033898
db: interpro

rpc9_yeast
type: Protein
evidence: Evidence 40ec997e-aa17-4bae-8dcb-3ad1745a3055 p 432651
entity reference: rpc9_yeast
name: DNA-directed RNA polymerase III subunit RPC9
comment: psi-mi participant
data source: intact

rpc9_yeast
type: Protein
evidence: Evidence bd371c09-5a94-43a6-a067-7a76b974a69f p 432647
entity reference: rpc9_yeast
name: DNA-directed RNA polymerase III subunit RPC9
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7531222 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7531222
db: intact

ExperimentalForm c65d9353-df99-4afb-afcf-4e10b563b148
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpc9_yeast
type: Protein
evidence: Evidence 9e2ca255-2e43-42b2-b10e-818340be504a p 432642
entity reference: rpc9_yeast
name: DNA-directed RNA polymerase III subunit RPC9
comment: psi-mi participant
data source: intact

rpc9_yeast
type: Protein
evidence: Evidence 5f2d24d5-061c-4713-9adf-a855f59337e0 p 432639
entity reference: rpc9_yeast
name: DNA-directed RNA polymerase III subunit RPC9
comment: psi-mi participant
data source: intact

rpc9_yeast
type: Protein
evidence: Evidence 5cfd6c70-0e97-4ec4-b0dc-37c967696e54 p 432634
entity reference: rpc9_yeast
name: DNA-directed RNA polymerase III subunit RPC9
comment: psi-mi participant
data source: intact

ExperimentalForm 9de183aa-e105-4d6a-a30a-fa0ec4ddf38d
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref imex IM-15332-5991 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5991
db: imex

UnificationXref mint MINT-2196330
type: UnificationXref
id: MINT-2196330
db: mint

RelationshipXref mint P39927
type: RelationshipXref
id: P39927
db: mint

ExperimentalForm ec1e1141-0244-4830-b7b3-befa12b88c2f
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpac2_yeast
type: Protein
evidence: Evidence 195c1f52-fa62-45cc-811b-e7176af11219 p 432750
entity reference: P28000
name: DNA-directed RNA polymerases I and III subunit RPAC2
comment: psi-mi participant
data source: intact

if2a_yeast
type: ProteinReference
sequence: MSTSHCRFYENKYPEIDDIVMVNVQQIAEMGAYVKLLEYDNIEGMILLSELSRRRIRSIQKLIRVGKNDVAVVLRVDKEKGYIDLSKRRVSSEDIIKCEEKYQKSKTVHSILRYCAEKFQIPLEELYKTIAWPLSRKFGHAYEAFKLSIIDETVWEGIEPPSKDVLDELKNYISKRLTPQAVKIRADVEVSCFSYEGIDAIKDALKSAEDMSTEQMQVKVKLVAAPLYVLTTQALDKQKGIEQLESAIEKITEVITKYGGVCNITMPPKAVTATEDAELQALLESKELDNRSDSEDDEDESDDE
xref: RelationshipXref interpro IPR003029
xref: RelationshipXref interpro IPR012340
xref: RelationshipXref interpro IPR022967
xref: RelationshipXref mint P20459
xref: RelationshipXref uniprotkb E9P8T6 secondary-ac
xref: RelationshipXref reactome R-SCE-72695
xref: RelationshipXref go GO 0006413
xref: RelationshipXref rcsb pdb 2A19
xref: RelationshipXref reactome R-SCE-72731
xref: RelationshipXref intact EBI-8915 identity
xref: RelationshipXref reactome R-SCE-382556
xref: RelationshipXref reactome R-SCE-156827
xref: RelationshipXref reactome R-SCE-381042
xref: RelationshipXref interpro IPR024055
xref: RelationshipXref interpro IPR024054
xref: RelationshipXref go GO 0033290
xref: RelationshipXref go GO 0043614
xref: RelationshipXref rcsb pdb 3J81
xref: RelationshipXref go GO 0005851
xref: RelationshipXref go GO 0005850
xref: RelationshipXref go GO 0001731
xref: RelationshipXref go GO 0010494
xref: RelationshipXref go GO 0043022
xref: RelationshipXref rcsb pdb 3JAQ
xref: RelationshipXref rcsb pdb 3JAP
xref: RelationshipXref dip DIP-2327N
xref: RelationshipXref reactome R-SCE-72702
xref: RelationshipXref sgd S000003767
xref: UnificationXref uniprot knowledgebase P20459
xref: RelationshipXref refseq NP 012540 3
xref: RelationshipXref go GO 0005840
xref: RelationshipXref rcsb pdb 2A1A
xref: RelationshipXref go GO 0003743
xref: RelationshipXref interpro IPR011488
xref: RelationshipXref uniprotkb D6VWI2 secondary-ac
xref: RelationshipXref rcsb pdb 1Q46
organism: http://identifiers.org/taxonomy/559292
name: Eukaryotic translation initiation factor 2 subunit alpha
name: SUI2
name: YJR007W
name: J1429
name: TIF211

RelationshipXref interpro IPR003196
type: RelationshipXref
id: IPR003196
db: interpro

rpc9_yeast
type: Protein
evidence: Evidence 23d9ae4d-40e9-4daf-b7ac-ce24c0338b0b p 432630
entity reference: rpc9_yeast
name: DNA-directed RNA polymerase III subunit RPC9
comment: psi-mi participant
data source: intact

RelationshipXref go GO 0005092
type: RelationshipXref
id: GO:0005092
db: gene ontology

rpc9_yeast
type: Protein
evidence: Evidence 32778726-5a3f-44e3-9ad9-575bac8ab928 p 432626
entity reference: rpc9_yeast
name: DNA-directed RNA polymerase III subunit RPC9
comment: psi-mi participant
data source: intact

RelationshipXref interpro IPR004539
type: RelationshipXref
id: IPR004539
db: interpro

Evidence d89f5daa-f21a-4d4f-81d6-dfb9f4bc54fa IM-15332-4382 430493 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpc9_yeast
type: Protein
evidence: Evidence daa5a1dc-83fb-4277-aa50-bf38133407e6 p 432618
entity reference: rpc9_yeast
name: DNA-directed RNA polymerase III subunit RPC9
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-7634 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-7634
db: imex

ExperimentalForm 5a20a19c-3bd2-4edd-ace7-3e8b8da19c5a
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref sgd S000002603
type: RelationshipXref
id: S000002603
db: sgd

rpac2_yeast
type: Protein
evidence: Evidence 0d1a5e11-7948-44e1-9dc8-81265ed4c159 p 432763
entity reference: P28000
name: DNA-directed RNA polymerases I and III subunit RPAC2
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7527629 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7527629
db: intact

RelationshipXref uniprotkb Q6B1V5 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: Q6B1V5
db: uniprot knowledgebase

RelationshipXref rcsb pdb 1EE5
type: RelationshipXref
id: 1EE5
db: protein data bank

RelationshipXref rcsb pdb 1EE4
type: RelationshipXref
id: 1EE4
db: protein data bank

rpc9_yeast
type: Protein
evidence: Evidence 04cb9554-deaf-41c9-8b98-e7afddba947e p 432611
entity reference: rpc9_yeast
name: DNA-directed RNA polymerase III subunit RPC9
comment: psi-mi participant
data source: intact

rpa190-rpa135-10
type: MolecularInteraction
xref: UnificationXref mint MINT-2201048
xref: RelationshipXref intact EBI-7522733 identity
xref: RelationshipXref imex IM-15332-10025 imex-primary
evidence: Evidence 645e9467-de67-40fa-b886-0c1792752e8e IM-15332-10025 431677 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.99
comment: author-confidence:z-score: 3.3548792767872
data source: intact
participant: Protein uniprotkb P22138 identity 1529029542242
participant: rpa1_yeast

ExperimentalForm 72345f91-ab1b-4de1-bead-d16234d41016
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

Evidence d1c9a7ae-cd3e-4af3-98c4-d71a214673e8 IM-15332-8819 432777 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpab1_yeast
type: Protein
evidence: Evidence 4eb02fda-0270-4338-9e74-509126036f6a p 432530
entity reference: rpab1_yeast
name: DNA-directed RNA polymerases I, II, and III subunit RPABC1
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7521187 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7521187
db: intact

ExperimentalForm 68e19c3e-ca75-4a4c-99c1-09434218a798
type: ExperimentalForm
experimental feature: ModificationFeature bc824f0c-fdb7-4931-b4e9-3a10289a4c35 430527
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref mint Q12377
type: RelationshipXref
id: Q12377
db: mint

RelationshipXref sgd S000001247
type: RelationshipXref
id: S000001247
db: sgd

RelationshipXref go GO 0006457
type: RelationshipXref
id: GO:0006457
db: gene ontology

RelationshipXref go GO 0006458
type: RelationshipXref
id: GO:0006458
db: gene ontology

RelationshipXref sgd S000001243
type: RelationshipXref
id: S000001243
db: sgd

UnificationXref mint MINT-2209562
type: UnificationXref
id: MINT-2209562
db: mint

RelationshipXref interpro IPR004519
type: RelationshipXref
id: IPR004519
db: interpro

rpb11-tfg1-3
type: MolecularInteraction
xref: RelationshipXref intact EBI-7526320 identity
xref: RelationshipXref imex IM-15332-12485 imex-primary
xref: UnificationXref mint MINT-2203191
evidence: Evidence 8a47be86-6bbe-408b-aaa6-e64f4930d2b2 IM-15332-12485 432153 430156
interaction type: physical association
comment: author-confidence:z-score: 0.726581072993436
comment: comment:mint
comment: author-confidence:reliability score: 0.676
data source: intact
participant: t2fa_yeast
participant: Protein uniprotkb P38902 identity 1529029542481

RelationshipXref imex IM-15332-7194 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-7194
db: imex

rpb10-rpa190-2
type: MolecularInteraction
xref: RelationshipXref intact EBI-7524572 identity
xref: RelationshipXref imex IM-15332-12053 imex-primary
xref: UnificationXref mint MINT-2202345
evidence: Evidence f6365fc2-2718-4a99-848a-1f9117a317f4 IM-15332-12053 431965 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.583
comment: comment:mint
comment: author-confidence:z-score: 2.50843323359681
data source: intact
participant: Protein uniprotkb P10964 identity 1529029542386
participant: rpab5_yeast

copa_yeast
type: Protein
evidence: Evidence e2190bd9-f52d-43ca-a729-289741124aea p 430606
entity reference: copa_yeast
name: Coatomer subunit alpha
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-3177 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-3177
db: imex

UnificationXref mint MINT-2196366
type: UnificationXref
id: MINT-2196366
db: mint

RelationshipXref mint P17890
type: RelationshipXref
id: P17890
db: mint

rpb9-rpo21-2
type: MolecularInteraction
xref: UnificationXref mint MINT-2204528
xref: RelationshipXref intact EBI-7530375 identity
xref: RelationshipXref imex IM-15332-12488 imex-primary
evidence: Evidence 1a85b6bc-0b10-453c-9040-5594f2521ca7 IM-15332-12488 432445 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 2.72407868290125
comment: comment:mint
comment: author-confidence:reliability score: 0.944
data source: intact
participant: Protein uniprotkb P27999 identity 1529029542627
participant: Protein uniprotkb P04050 identity 1529029542626

ExperimentalForm e3ebfd24-91db-440d-80a1-c9a3c2888e92
type: ExperimentalForm
experimental feature: ModificationFeature 11117c22-e179-4f26-954a-d28170a326e2 432248
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

tho2-hpr1-22
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-2348 imex-primary
xref: UnificationXref mint MINT-2199446
xref: RelationshipXref intact EBI-7520334 identity
evidence: Evidence af555f78-5752-40b0-8885-925d1deda0e1 IM-15332-2348 431321 430156
interaction type: physical association
comment: comment:mint
comment: author-confidence:reliability score: 0.99
comment: author-confidence:z-score: 6.55369747037525
data source: intact
participant: Protein uniprotkb P17629 identity 1529029542064
participant: Protein uniprotkb P53552 identity 1529029542065

RelationshipXref interpro IPR033858
type: RelationshipXref
id: IPR033858
db: interpro

ExperimentalForm fbd58c20-44d2-4554-b795-ac48e627f10d
type: ExperimentalForm
experimental feature: ModificationFeature 76eda9a6-6b85-4e04-a117-5ef459cd8f6e 432575
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm db055f2f-3e1e-4d79-a33a-29231a00bcb2
type: ExperimentalForm
experimental feature: ModificationFeature c6d97e16-c710-47e7-bfb7-0d8ee4c19399 430744
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref go GO 0006469
type: RelationshipXref
id: GO:0006469
db: gene ontology

rpc17-rpc37-1
type: MolecularInteraction
xref: RelationshipXref intact EBI-7532064 identity
xref: RelationshipXref imex IM-15332-4400 imex-primary
xref: UnificationXref mint MINT-2205493
evidence: Evidence f625f918-1eec-42a4-a751-f5550c56d499 IM-15332-4400 432653 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.989
comment: comment:mint
comment: author-confidence:z-score: 2.43824461454143
data source: intact
participant: Protein uniprotkb P36121 identity 1529029542731
participant: rpc9_yeast

RelationshipXref imex IM-15332-8822 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-8822
db: imex

RelationshipXref intact EBI-7519364 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7519364
db: intact

rpa190-rpa49-7
type: MolecularInteraction
xref: UnificationXref mint MINT-2201156
xref: RelationshipXref intact EBI-7522914 identity
xref: RelationshipXref imex IM-15332-11245 imex-primary
evidence: Evidence 19322a55-7060-4f66-be96-66b664ca2e91 IM-15332-11245 431701 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.983
comment: author-confidence:z-score: 9.3692208553727
comment: comment:mint
data source: intact
participant: Protein uniprotkb Q01080 identity 1529029542255
participant: rpa1_yeast

RelationshipXref go GO 0070682
type: RelationshipXref
id: GO:0070682
db: gene ontology

UnificationXref mint MINT-2197718
type: UnificationXref
id: MINT-2197718
db: mint

RelationshipXref intact EBI-7517902 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7517902
db: intact

RelationshipXref imex IM-15332-9626 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-9626
db: imex

RelationshipXref interpro IPR019364
type: RelationshipXref
id: IPR019364
db: interpro

ExperimentalForm 15aa9a19-ef7b-46b5-b922-d90a977f1ded
type: ExperimentalForm
experimental feature: ModificationFeature c27557cd-1c46-42c1-901d-2a1e82fb22fc 433384
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7534240 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7534240
db: intact

RelationshipXref go GO 0007535
type: RelationshipXref
id: GO:0007535
db: gene ontology

Evidence 8a42f09c-21a8-44e0-aaeb-48b29c3ed51c IM-15332-4391 431685 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref interpro IPR003152
type: RelationshipXref
id: IPR003152
db: interpro

RelationshipXref interpro IPR003151
type: RelationshipXref
id: IPR003151
db: interpro

RelationshipXref intact EBI-7515822 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7515822
db: intact

RelationshipXref rcsb pdb 2HZS
type: RelationshipXref
id: 2HZS
db: protein data bank

RelationshipXref intact EBI-7521796 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7521796
db: intact

RelationshipXref rcsb pdb 2HZM
type: RelationshipXref
id: 2HZM
db: protein data bank

ExperimentalForm ae3d94cb-0ffe-4a44-83e8-90e7f4f7117f
type: ExperimentalForm
experimental feature: ModificationFeature b863788b-5e2e-4f10-a193-5cfb462e94ee 430499
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref go GO 0006183
type: RelationshipXref
id: GO:0006183
db: gene ontology

rpn1-rpt3-11
type: MolecularInteraction
xref: RelationshipXref intact EBI-7542778 identity
xref: RelationshipXref imex IM-15332-10044 imex-primary
xref: UnificationXref mint MINT-2210732
evidence: Evidence 6361a54a-5e4c-49bf-b04a-e37068af39a4 IM-15332-10044 433817 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.989
comment: author-confidence:z-score: 0.493216633740828
comment: comment:mint
data source: intact
participant: Protein uniprotkb P33298 identity 1529029543313
participant: Protein uniprotkb P38764 identity 1529029543312

rpb9-gdh3
type: MolecularInteraction
xref: UnificationXref mint MINT-2205060
xref: RelationshipXref intact EBI-7531387 identity
xref: RelationshipXref imex IM-15332-10856 imex-primary
evidence: Evidence 705be85e-72f8-40cf-85e8-bd55abfad7bf IM-15332-10856 432557 430156
interaction type: physical association
comment: author-confidence:z-score: -0.0499967215984424
comment: author-confidence:reliability score: 0.475
comment: comment:mint
data source: intact
participant: Protein uniprotkb P27999 identity 1529029542682
participant: Protein uniprotkb P39708 identity 1529029542683

ExperimentalForm 617f478d-e909-4d39-a984-b16837ea0c29
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref mint Q12347
type: RelationshipXref
id: Q12347
db: mint

Evidence a285b964-c659-4c24-afef-d70dd77e7092 IM-15332-5179 432377 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref mint Q12343
type: RelationshipXref
id: Q12343
db: mint

RelationshipXref sgd S000001210
type: RelationshipXref
id: S000001210
db: sgd

ExperimentalForm 5eb8bcd5-0e85-48bb-98b1-5e1a2d65d153
type: ExperimentalForm
experimental feature: ModificationFeature 8a289e06-7b52-4fd1-b4d4-1ea0f16dc73e 433372
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 33e7f9f8-6275-4dd0-8aa8-0ac0f65221c1
type: ExperimentalForm
experimental feature: ModificationFeature d2bde6bd-d3be-473a-ab90-c156387d4aa9 431484
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

UnificationXref mint MINT-2197736
type: UnificationXref
id: MINT-2197736
db: mint

RelationshipXref go GO 0006177
type: RelationshipXref
id: GO:0006177
db: gene ontology

ExperimentalForm 8f8d4da5-8619-4528-b4cd-e0f2b2c42bd0
type: ExperimentalForm
experimental feature: ModificationFeature 5f6a6cd7-a2eb-40ea-a963-887fca40eb1f 432715
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

UnificationXref uniprot knowledgebase P38138
type: UnificationXref
id: P38138
db: uniprot knowledgebase

ExperimentalForm 45744dc8-d55f-47c1-ac58-d2b1b3286681
type: ExperimentalForm
experimental feature: ModificationFeature 47835c18-debf-4251-a1fe-b5fdd8cfed94 432607
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref rcsb pdb 3M4O
type: RelationshipXref
id: 3M4O
db: protein data bank

RelationshipXref intact EBI-7530343 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7530343
db: intact

RelationshipXref go GO 0006491
type: RelationshipXref
id: GO:0006491
db: gene ontology

UnificationXref mint MINT-2208986
type: UnificationXref
id: MINT-2208986
db: mint

RelationshipXref imex IM-15332-5169 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5169
db: imex

RelationshipXref sgd S000001207
type: RelationshipXref
id: S000001207
db: sgd

ExperimentalForm 42674a73-c327-4844-9f94-54f578306bb0
type: ExperimentalForm
experimental feature: ModificationFeature 24bdc01c-69f8-4dbb-9ec6-b28f6f65c810 431972
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref interpro IPR033825
type: RelationshipXref
id: IPR033825
db: interpro

ExperimentalForm 3381b34b-5782-4c8b-a3b7-dd96c780e380
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 70e785bb-0b13-43b8-8fc3-3e710ef9bc79
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7531258 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7531258
db: intact

rir3_yeast
type: Protein
evidence: Evidence a463b28c-76e2-4403-992a-ee7b110adc11 p 431406
entity reference: rir3_yeast
name: Ribonucleoside-diphosphate reductase large chain 2
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 3M3Y
type: RelationshipXref
id: 3M3Y
db: protein data bank

RelationshipXref go GO 0070651
type: RelationshipXref
id: GO:0070651
db: gene ontology

ExperimentalForm e1521b0f-9145-415e-8db3-04a74023033e
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm e56eb97e-837e-49c8-b529-4b9f3224a723
type: ExperimentalForm
experimental feature: ModificationFeature 3169677d-c8ff-476f-8379-631d60f34ba9 431136
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref rcsb pdb 5TGM
type: RelationshipXref
id: 5TGM
db: protein data bank

rpa14_yeast
type: Protein
evidence: Evidence b53f578b-03e0-44c2-bc46-fd996e619dc7 p 431566
entity reference: P50106
name: DNA-directed RNA polymerase I subunit RPA14
comment: psi-mi participant
data source: intact

RelationshipXref reactome R-SCE-2559580
type: RelationshipXref
id: R-SCE-2559580
db: reactome

RelationshipXref intact EBI-7528265 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7528265
db: intact

Evidence cc182672-8c12-4830-93b2-2399acb2050a IM-15332-11629 430357 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm 1174f48b-2efe-44d6-8559-b74eba46a5d8
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref rcsb pdb 5TGA
type: RelationshipXref
id: 5TGA
db: protein data bank

RelationshipXref mint Q12321
type: RelationshipXref
id: Q12321
db: mint

rpab1_yeast
type: Protein
evidence: Evidence c640952c-4188-4dc8-b12d-649a01f463fa p 432260
entity reference: rpab1_yeast
name: DNA-directed RNA polymerases I, II, and III subunit RPABC1
comment: psi-mi participant
data source: intact

rpab1_yeast
type: Protein
evidence: Evidence d017905a-14c8-424c-b903-9ca6aba6e384 p 433112
entity reference: rpab1_yeast
name: DNA-directed RNA polymerases I, II, and III subunit RPABC1
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-12051 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12051
db: imex

rpb8-yp225-4
type: MolecularInteraction
xref: UnificationXref mint MINT-2204075
xref: RelationshipXref imex IM-15332-3986 imex-primary
xref: RelationshipXref intact EBI-7528628 identity
evidence: Evidence d1c8f48a-a00d-4255-b4bc-e47f3e72bb63 IM-15332-3986 432349 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.989
comment: comment:mint
comment: author-confidence:z-score: 9.71496930466641
data source: intact
participant: Protein uniprotkb Q08971 identity 1529029542579
participant: rpab3_yeast

rpa14_yeast
type: Protein
evidence: Evidence c0d859af-06c7-4287-af03-30c4f935466e p 431586
entity reference: P50106
name: DNA-directed RNA polymerase I subunit RPA14
comment: psi-mi participant
data source: intact

RelationshipXref dip DIP-1629N
type: RelationshipXref
id: DIP-1629N
db: database of interacting proteins

rpa14_yeast
type: Protein
evidence: Evidence b95525fd-3b62-413f-9bc8-8b0fb2f9f249 p 431591
entity reference: P50106
name: DNA-directed RNA polymerase I subunit RPA14
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2208968
type: UnificationXref
id: MINT-2208968
db: mint

RelationshipXref interpro IPR032460
type: RelationshipXref
id: IPR032460
db: interpro

ExperimentalForm af8900f3-a6ce-4a22-ae6b-8f434bb809e5
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rir3_yeast
type: Protein
evidence: Evidence 12c54fb2-ef5d-4a55-b8f1-cc581da43bd5 p 431416
entity reference: rir3_yeast
name: Ribonucleoside-diphosphate reductase large chain 2
comment: psi-mi participant
data source: intact

rpn1-rpt5-7
type: MolecularInteraction
xref: RelationshipXref intact EBI-7543638 identity
xref: UnificationXref mint MINT-2211074
xref: RelationshipXref imex IM-15332-3602 imex-primary
evidence: Evidence 37826cfe-36ec-4f9c-b459-e0c4db4ee100 IM-15332-3602 433893 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.984
comment: comment:mint
comment: author-confidence:z-score: 1.36227212017383
data source: intact
participant: prs6a_yeast
participant: Protein uniprotkb P38764 identity 1529029543351

RelationshipXref rcsb pdb 2I7X
type: RelationshipXref
id: 2I7X
db: protein data bank

ExperimentalForm f2705fef-0a66-42d3-a18a-631731bb974a
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref imex IM-15332-4410 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-4410
db: imex

Evidence 9e18347b-f21f-448a-9d2b-46de3790462b IM-15332-3175 432493 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref cygd YPL220w
type: RelationshipXref
id: YPL220w
db: cygd

ExperimentalForm d748d176-a019-4233-80d6-bf6c61431a54
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 70650d73-df86-400b-bcaa-64a548df0f2e
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref go GO 2000105
type: RelationshipXref
id: GO:2000105
db: gene ontology

RelationshipXref interpro IPR019313
type: RelationshipXref
id: IPR019313
db: interpro

RelationshipXref interpro IPR003107
type: RelationshipXref
id: IPR003107
db: interpro

ExperimentalForm 265891d4-181b-4eae-af3d-f56a441585ea
type: ExperimentalForm
experimental feature: ModificationFeature e772f784-0317-4f61-a537-3ebae168a4f2 433344
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rim1-spt16
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-2738 imex-primary
xref: RelationshipXref intact EBI-7518678 identity
xref: UnificationXref mint MINT-2198330
evidence: Evidence 0dc721c4-d37e-4287-ba55-a528ff3956d7 IM-15332-2738 431073 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.77
comment: comment:mint
comment: author-confidence:z-score: 4.3851318844765
data source: intact
participant: Protein uniprotkb P32445 identity 1529029541941
participant: spt16_yeast

rpa43-rpb5
type: MolecularInteraction
xref: RelationshipXref intact EBI-7523642 identity
xref: RelationshipXref imex IM-15332-7635 imex-primary
xref: UnificationXref mint MINT-2201660
evidence: Evidence 2274f763-31e3-41c8-87bc-3b311c7a4df3 IM-15332-7635 431813 430156
interaction type: physical association
comment: comment:mint
comment: author-confidence:z-score: 7.80054873668701
comment: author-confidence:reliability score: 0.968
data source: intact
participant: Protein uniprotkb P46669 identity 1529029542311
participant: rpab1_yeast

RelationshipXref go GO 0070628
type: RelationshipXref
id: GO:0070628
db: gene ontology

ExperimentalForm bcd0a469-e2d4-4e40-b413-7139086a5c61
type: ExperimentalForm
experimental feature: ModificationFeature 4de40137-4636-4903-927e-8b3d1967320a 433443
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref refseq NP 012034 1
type: RelationshipXref
id: NP_012034.1
db: refseq

RelationshipXref intact EBI-7541451 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7541451
db: intact

RelationshipXref intact EBI-28808 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-28808
db: intact

RelationshipXref uniprotkb D6VTT5 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VTT5
db: uniprot knowledgebase

ExperimentalForm d6b6848e-f91a-42bd-a996-c6749b4da366
type: ExperimentalForm
experimental feature: ModificationFeature f4577853-18e4-4a26-80db-51f3f106b25f 430951
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

t2fb_yeast
type: Protein
evidence: Evidence 0157c1e4-a8b9-48e7-88f1-b09e21e60485 p 432548
entity reference: P41896
name: Transcription initiation factor IIF subunit beta
comment: psi-mi participant
data source: intact

Evidence caa93417-3995-4e60-ad66-815a36c0ec68 IM-15332-5991 433545 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

t2fb_yeast
type: Protein
evidence: Evidence bfe42382-f9a4-4e4b-b017-493a067263a6 p 432538
entity reference: P41896
name: Transcription initiation factor IIF subunit beta
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-1961 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1961
db: imex

RelationshipXref imex IM-15332-12061 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12061
db: imex

Evidence f3364737-3a7d-496d-b7a9-266732fb373a IM-15332-8415 431861 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm 60407450-3dd4-454f-bf5b-913367e4a477
type: ExperimentalForm
experimental feature: ModificationFeature 1f7f4ff3-7783-43c1-8f9b-a010f911d28a 430944
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpc40-rpa43-3
type: MolecularInteraction
xref: RelationshipXref intact EBI-7535834 identity
xref: RelationshipXref imex IM-15332-9211 imex-primary
xref: UnificationXref mint MINT-2207474
evidence: Evidence c4d8aa09-8e45-4056-8676-6429b607f456 IM-15332-9211 433093 430156
interaction type: physical association
comment: comment:mint
comment: author-confidence:reliability score: 0.99
comment: author-confidence:z-score: 0.484380881306414
data source: intact
participant: Protein uniprotkb P07703 identity 1529029542951
participant: rpa43_yeast

Evidence faf7c1cc-7c5b-42ca-b987-0a6bcf4e3b45 IM-15332-7645 432869 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref imex IM-15332-5188 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5188
db: imex

RelationshipXref reactome R-SCE-189085
type: RelationshipXref
id: R-SCE-189085
db: reactome

RelationshipXref imex IM-15332-3987 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-3987
db: imex

ExperimentalForm a42f857d-5961-43be-8a64-43eb6fa2cccc
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpg1-prt1-2
type: MolecularInteraction
xref: UnificationXref mint MINT-2209022
xref: RelationshipXref imex IM-15332-6389 imex-primary
xref: RelationshipXref intact EBI-7538985 identity
evidence: Evidence ce9e233b-713b-4f66-99c0-7df5d37ea3f6 IM-15332-6389 433437 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 6.23665635993485
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P06103 identity 1529029543123
participant: Protein uniprotkb P38249 identity 1529029543122

UnificationXref mint MINT-2208932
type: UnificationXref
id: MINT-2208932
db: mint

RelationshipXref intact EBI-7527032 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7527032
db: intact

RelationshipXref rcsb pdb 5TBW
type: RelationshipXref
id: 5TBW
db: protein data bank

rom2-ipp1-2
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-10023 imex-primary
xref: UnificationXref mint MINT-2200184
xref: RelationshipXref intact EBI-7521327 identity
evidence: Evidence 63dbdaaf-e69b-4da2-a4cc-551d027c2a57 IM-15332-10023 431485 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.989
comment: author-confidence:z-score: 8.76177518066502
comment: comment:mint
data source: intact
participant: Protein uniprotkb P51862 identity 1529029542146
participant: Protein uniprotkb P00817 identity 1529029542147

Evidence aeae18df-2ea5-45a1-ab9f-27c2df0f97eb IM-15332-10436 431669 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref rcsb pdb 2ZLF
type: RelationshipXref
id: 2ZLF
db: protein data bank

UnificationXref mint MINT-2207582
type: UnificationXref
id: MINT-2207582
db: mint

ExperimentalForm 064c2b59-0e28-4618-8c59-b3f5b8b95d9a
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm d3389031-da82-4e56-bc82-53214142075c
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref imex IM-15332-7206 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-7206
db: imex

RelationshipXref intact EBI-7519379 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7519379
db: intact

Evidence f9f7f9cf-421a-4379-913b-2879aaa32803 IM-15332-9208 432525 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpa43_yeast
type: Protein
evidence: Evidence 319c3bc8-7383-477b-bfdb-d0f4f953b334 p 431780
entity reference: P46669
name: DNA-directed RNA polymerase I subunit RPA43
comment: psi-mi participant
data source: intact

ExperimentalForm 02cf5da0-4c8f-4074-8f95-30f56e09a3cf
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7523877 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7523877
db: intact

RelationshipXref go GO 0006109
type: RelationshipXref
id: GO:0006109
db: gene ontology

RelationshipXref go GO 0006102
type: RelationshipXref
id: GO:0006102
db: gene ontology

ExperimentalForm fd3389aa-81bf-4a44-943f-45aa73b4b462
type: ExperimentalForm
experimental feature: ModificationFeature 6edd564a-6f42-488a-b17d-cef89dd8f658 432315
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref interpro IPR032413
type: RelationshipXref
id: IPR032413
db: interpro

Evidence a076608d-b895-492a-af1a-eae32d49cbef IM-15332-5583 431105 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref mint MINT-2208914
type: UnificationXref
id: MINT-2208914
db: mint

RelationshipXref imex IM-15332-12872 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12872
db: imex

RelationshipXref intact EBI-7530458 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7530458
db: intact

rpa43_yeast
type: Protein
evidence: Evidence 133764a4-eca9-4670-8f11-cd48ac174aa5 p 431766
entity reference: P46669
name: DNA-directed RNA polymerase I subunit RPA43
comment: psi-mi participant
data source: intact

rpa43_yeast
type: Protein
evidence: Evidence e315fc7d-fced-44db-9dcd-4957373bc646 p 431762
entity reference: P46669
name: DNA-directed RNA polymerase I subunit RPA43
comment: psi-mi participant
data source: intact

ExperimentalForm ddb9df6b-46c0-4c6a-a8b4-f649492d4a03
type: ExperimentalForm
experimental feature: ModificationFeature d2f173a6-d38d-4cd9-9d97-0b24d8dcf128 431379
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-3997 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-3997
db: imex

UnificationXref mint MINT-2207564
type: UnificationXref
id: MINT-2207564
db: mint

RelationshipXref intact EBI-7515693 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7515693
db: intact

ExperimentalForm fd952991-6a67-47b2-9169-70386fc97dbe
type: ExperimentalForm
experimental feature: ModificationFeature 0f69866e-1efb-4e8a-b710-7cc610be0db5 430964
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-5979 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5979
db: imex

UnificationXref mint MINT-2196888
type: UnificationXref
id: MINT-2196888
db: mint

rpa43_yeast
type: Protein
evidence: Evidence 384ea34c-8abd-4706-ac9f-0b3f460079bc p 431746
entity reference: P46669
name: DNA-directed RNA polymerase I subunit RPA43
comment: psi-mi participant
data source: intact

ExperimentalForm 9ee05b12-16db-4dc4-a0ab-afcabd781c40
type: ExperimentalForm
experimental feature: ModificationFeature cf52db91-56bd-40ef-8129-b6b93f886d2f 433048
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm d0660a07-d3af-435f-8e08-eaa96246c60b
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref reactome R-SCE-444257
type: RelationshipXref
id: R-SCE-444257
db: reactome

tex1_yeast
type: ProteinReference
sequence: MSTIGAVDILNQKTITSEVAASVTSKYLQSTFSKGNTSHIEDKRFIHVSSRSHSRFTSTPITPNEILSLKFHVSGSSMAYSRMDGSLTVWFIKDASFDKSVEVYIPDCCGSDKLATDLSWNPTSLNQIAVVSNSSEISLLLINEKSLTASKLRTLSLGSKTKVNTCLYDPLGNWLLAATKSEKIYLFDVKKDHSSVCSLNISDISQEDNDVVYSLAWSNGGSHIFIGFKSGYLAILKAKHGILEVCTKIKAHTGPITEIKMDPWGRNFITGSIDGNCYVWNMKSLCCELIINDLNSAVTTLDVCHLGKILGICTEDEMVYFYDLNSGNLLHSKSLANYKTDPVLKFYPDKSWYIMSGKNDTLSNHFVKNEKNLITYWKDMFDNTMIEKRRKNNGGGNNHNKRTSKNTDRIGKDRPSRFNSKK
xref: RelationshipXref go GO 0006406
xref: RelationshipXref intact EBI-29234 identity
xref: RelationshipXref go GO 0000346
xref: RelationshipXref sgd S000005197
xref: RelationshipXref interpro IPR015943
xref: RelationshipXref go GO 0006355
xref: RelationshipXref mint P53851
xref: RelationshipXref go GO 0006351
xref: RelationshipXref go GO 0000445
xref: RelationshipXref interpro IPR036322
xref: RelationshipXref refseq NP 014146 1
xref: RelationshipXref dip DIP-2820N
xref: UnificationXref uniprot knowledgebase P53851
xref: RelationshipXref interpro IPR001680
xref: RelationshipXref interpro IPR017986
xref: RelationshipXref uniprotkb D6W0U0 secondary-ac
organism: http://identifiers.org/taxonomy/559292
name: TEX1
name: YNL253W
name: Protein TEX1
name: Trex component 1
name: N0860

Evidence 3f9750f8-5a9b-4df5-a29e-e0583580a114 IM-15332-10863 433629 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref mint MINT-2196870
type: UnificationXref
id: MINT-2196870
db: mint

rnr1-rnr3-14
type: MolecularInteraction
xref: UnificationXref mint MINT-2199878
xref: RelationshipXref imex IM-15332-2349 imex-primary
xref: RelationshipXref intact EBI-7520946 identity
evidence: Evidence ccc56128-b733-402c-a5a8-2875ca2b00a0 IM-15332-2349 431417 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.906
comment: comment:homomint
comment: author-confidence:z-score: 0.131747559464653
comment: comment:mint
data source: intact
participant: Protein uniprotkb P21524 identity 1529029542113
participant: Protein uniprotkb P21672 identity 1529029542112

RelationshipXref rcsb pdb 1E6A
type: RelationshipXref
id: 1E6A
db: protein data bank

UnificationXref mint MINT-2207546
type: UnificationXref
id: MINT-2207546
db: mint

ExperimentalForm 5f1b0091-fa1c-4180-8dea-e752d11059a0
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref imex IM-15332-12487 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12487
db: imex

RelationshipXref refseq NP 012182 1
type: RelationshipXref
id: NP_012182.1
db: refseq

RelationshipXref intact EBI-7521462 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7521462
db: intact

RelationshipXref uniprotkb D6VTB3 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VTB3
db: uniprot knowledgebase

UnificationXref mint MINT-2206195
type: UnificationXref
id: MINT-2206195
db: mint

Evidence 4dc98cb4-1dea-4153-83ff-cc57d436414e IM-15332-3172 432237 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

hrb1_yeast
type: Protein
evidence: Evidence 3d138b1f-dd44-43bd-b4c0-1be74c8137c0 p 431274
entity reference: P38922
name: Protein HRB1
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-16809 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-16809
db: intact

RelationshipXref imex IM-15332-5989 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5989
db: imex

ExperimentalForm d1dae76e-2e5c-42c0-b20f-76531cbc446c
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

tho2-hrb1-3
type: MolecularInteraction
xref: UnificationXref mint MINT-2199212
xref: RelationshipXref intact EBI-7520017 identity
xref: RelationshipXref imex IM-15332-9603 imex-primary
evidence: Evidence 34feaa48-a13a-482f-bf06-313f9bfdcdbe IM-15332-9603 431269 430156
interaction type: physical association
comment: comment:mint
comment: author-confidence:reliability score: 0.762
comment: author-confidence:z-score: 0.259181413982388
data source: intact
participant: hrb1_yeast
participant: Protein uniprotkb P53552 identity 1529029542039

ExperimentalForm 41f27515-6ee0-4e7f-bd4c-6cab53d361e3
type: ExperimentalForm
experimental feature: ModificationFeature 9ffd26ab-1630-4928-9ed6-5542acdd2f2b 431059
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref go GO 0034063
type: RelationshipXref
id: GO:0034063
db: gene ontology

hrb1_yeast
type: Protein
evidence: Evidence 0f6b9ec7-d123-4dd8-83c9-902e4d057325 p 431270
entity reference: P38922
name: Protein HRB1
comment: psi-mi participant
data source: intact

RelationshipXref interpro IPR011710
type: RelationshipXref
id: IPR011710
db: interpro

UnificationXref mint MINT-2196852
type: UnificationXref
id: MINT-2196852
db: mint

RelationshipXref intact EBI-7517869 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7517869
db: intact

UnificationXref mint MINT-2207528
type: UnificationXref
id: MINT-2207528
db: mint

rpc40-rpc53-1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-11646 imex-primary
xref: RelationshipXref intact EBI-7536359 identity
xref: UnificationXref mint MINT-2207906
evidence: Evidence 1fdde8c9-71a9-43d0-8e64-c7435fe4d6dd IM-15332-11646 433189 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.983
comment: author-confidence:z-score: 7.96766951434538
comment: comment:mint
data source: intact
participant: Protein uniprotkb P07703 identity 1529029542999
participant: Protein uniprotkb P25441 identity 1529029542998

Evidence f1cc75b0-ad7b-4a8a-8333-355f934e6144 IM-15332-7620 430425 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm 772b6e15-6384-42e6-9b3b-c800a0594df9
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref uniprotkb D6VQE9 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VQE9
db: uniprot knowledgebase

RelationshipXref interpro IPR011709
type: RelationshipXref
id: IPR011709
db: interpro

UnificationXref mint MINT-2206177
type: UnificationXref
id: MINT-2206177
db: mint

RelationshipXref imex IM-15332-12871 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12871
db: imex

RelationshipXref reactome R-SCE-8849471
type: RelationshipXref
id: R-SCE-8849471
db: reactome

Evidence 57734b42-dc2d-46fb-ac6c-77dc30c4618a IM-15332-2354 432073 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpa190-rpa135-13
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-6375 imex-primary
xref: RelationshipXref intact EBI-7523093 identity
xref: UnificationXref mint MINT-2201228
evidence: Evidence 5073df6e-3058-4410-825e-222d96b9dcf3 IM-15332-6375 431717 430156
interaction type: physical association
comment: author-confidence:z-score: 4.45357601985033
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P22138 identity 1529029542262
participant: Protein uniprotkb P10964 identity 1529029542263

Evidence 369cb62b-2e7d-4d85-b681-cedb0f592146 IM-15332-1214 431825 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref go GO 0034045
type: RelationshipXref
id: GO:0034045
db: gene ontology

ExperimentalForm 17ba1bd9-286f-403a-b104-923c6b1fb73d
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7541483 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7541483
db: intact

UnificationXref mint MINT-2196834
type: UnificationXref
id: MINT-2196834
db: mint

ExperimentalForm bef9dcf9-8f9a-4ee1-b860-7ef41fe48572
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 7845bd96-ed73-4fa1-9943-e2fa9e143446
type: ExperimentalForm
experimental feature: ModificationFeature 634868de-6953-4b74-8361-50c36aec42d0 432208
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 8ffeb0c0-e2ca-453d-a046-a49d699b2590
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref mint MINT-2195483
type: UnificationXref
id: MINT-2195483
db: mint

UnificationXref mint MINT-2206159
type: UnificationXref
id: MINT-2206159
db: mint

RelationshipXref intact EBI-7518007 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7518007
db: intact

ExperimentalForm 1ff1fd57-e426-45b9-b9bd-19122c8f4f5f
type: ExperimentalForm
experimental feature: ModificationFeature 0dc550cf-d21c-4055-b951-8b581aa6944a 432728
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref interpro IPR026541
type: RelationshipXref
id: IPR026541
db: interpro

RelationshipXref intact EBI-7523892 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7523892
db: intact

ExperimentalForm 8e4edab0-5e6a-46b4-bf5d-a57942302926
type: ExperimentalForm
experimental feature: ModificationFeature b72457d0-7865-4c7f-810c-176b4c2b7854 433387
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

Evidence 7d4365ed-4672-4277-87f8-de62b9918a2b IM-15332-2347 431309 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref rcsb pdb 3HOW
type: RelationshipXref
id: 3HOW
db: protein data bank

RelationshipXref intact EBI-15767 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-15767
db: intact

RelationshipXref intact EBI-7534065 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7534065
db: intact

RelationshipXref interpro IPR000788
type: RelationshipXref
id: IPR000788
db: interpro

UnificationXref mint MINT-2196816
type: UnificationXref
id: MINT-2196816
db: mint

UnificationXref mint MINT-2206141
type: UnificationXref
id: MINT-2206141
db: mint

RelationshipXref go GO 0006457 process
type: RelationshipXref
relationship type: MI:0359
id: GO:0006457
db: gene ontology

RelationshipXref rcsb pdb 5T94
type: RelationshipXref
id: 5T94
db: protein data bank

RelationshipXref imex IM-15332-1951 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1951
db: imex

ExperimentalForm d6cce5d6-144c-41f7-83b6-04170c99174d
type: ExperimentalForm
experimental feature: ModificationFeature 751fccc5-d823-4f1e-bcea-c729ab27e31b 433127
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 2f539b88-0aae-4149-8879-b5d35cf723db
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref imex IM-15332-1577 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1577
db: imex

RelationshipXref imex IM-15332-2755 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-2755
db: imex

ExperimentalForm be902015-f750-4246-85d4-d3ca08d9b6f2
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 0621c3b0-bea1-4b52-8a6a-e08f85a4600b
type: ExperimentalForm
experimental feature: ModificationFeature adf11867-6181-4f81-a083-c14e1c6b50de 433615
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7528185 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7528185
db: intact

rpd3_yeast
type: Protein
evidence: Evidence 1988e6fd-e293-4222-bb65-84455e091f56 p 433383
entity reference: rpd3_yeast
name: Histone deacetylase RPD3
comment: psi-mi participant
data source: intact

rpd3_yeast
type: Protein
evidence: Evidence e4355fad-06fe-4d9b-8530-6d343dcc2a88 p 433378
entity reference: rpd3_yeast
name: Histone deacetylase RPD3
comment: psi-mi participant
data source: intact

rpd3_yeast
type: Protein
evidence: Evidence 57fc171c-228d-478e-a245-ed779d544b71 p 433374
entity reference: rpd3_yeast
name: Histone deacetylase RPD3
comment: psi-mi participant
data source: intact

ExperimentalForm 175ad1b2-4e9c-4a54-85d8-7c6557124a4b
type: ExperimentalForm
experimental feature: ModificationFeature c726a753-8c33-4137-9221-174d9020edee 430627
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 3c4c2e99-9926-4316-900e-61d155b9e5c9
type: ExperimentalForm
experimental feature: ModificationFeature 2663e43b-2f37-43b9-8e0c-0f1ad1ac937b 430791
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 35b251f1-49bd-41d1-83b1-8378737d2709
type: ExperimentalForm
experimental feature: ModificationFeature 0b1da6b8-494a-4289-abfb-bfff7af2b50f 431984
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7531966 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7531966
db: intact

RelationshipXref rcsb pdb 5SVA
type: RelationshipXref
id: 5SVA
db: protein data bank

rpd3_yeast
type: Protein
evidence: Evidence 22c3118d-5150-4b05-a8e3-6da269fb9a8d p 433371
entity reference: rpd3_yeast
name: Histone deacetylase RPD3
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2206123
type: UnificationXref
id: MINT-2206123
db: mint

rpd3_yeast
type: Protein
evidence: Evidence f7e6364f-c9cd-4325-9f48-e0ec911e828f p 433362
entity reference: rpd3_yeast
name: Histone deacetylase RPD3
comment: psi-mi participant
data source: intact

rpd3_yeast
type: Protein
evidence: Evidence b14965e4-6003-4319-864b-0232f173e598 p 433359
entity reference: rpd3_yeast
name: Histone deacetylase RPD3
comment: psi-mi participant
data source: intact

rpd3_yeast
type: Protein
evidence: Evidence 05898bbf-e479-4c3b-9665-e124c5ea38b8 p 433355
entity reference: rpd3_yeast
name: Histone deacetylase RPD3
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 5T6R
type: RelationshipXref
id: 5T6R
db: protein data bank

RelationshipXref refseq NP 013875 1
type: RelationshipXref
id: NP_013875.1
db: refseq

RelationshipXref reactome REACT 290856
type: RelationshipXref
id: REACT_290856
db: reactome

rpac2_yeast
type: Protein
evidence: Evidence a1780e4a-08b5-45ba-9715-1c3b31292abf p 432807
entity reference: P28000
name: DNA-directed RNA polymerases I and III subunit RPAC2
comment: psi-mi participant
data source: intact

ExperimentalForm 7fbc7407-964f-4c4e-9e24-e30d4dd9505a
type: ExperimentalForm
experimental feature: ModificationFeature b9b4cdd5-deb8-4ca8-8390-44c5a38d0ed1 431300
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

UnificationXref mint MINT-2195447
type: UnificationXref
id: MINT-2195447
db: mint

RelationshipXref imex IM-15332-10441 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-10441
db: imex

rfa1-dna2-3
type: MolecularInteraction
xref: UnificationXref mint MINT-2196726
xref: RelationshipXref imex IM-15332-10845 imex-primary
xref: RelationshipXref intact EBI-7516789 identity
evidence: Evidence 19a23be4-0b95-4607-811f-99d419b8e65e IM-15332-10845 430717 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 1.21443860553558
comment: comment:mint
comment: author-confidence:reliability score: 0.968
data source: intact
participant: dna2_yeast
participant: rfa1_yeast

hos3_yeast
type: ProteinReference
sequence: MSSKHSDPLERFYKQFQAFVQNNPNVISAARAAAQIPESAKAVVVLSPYSLQHVFPREWVTKSYRKTIVERPERLLASSMGISAAITMYPSLFTLKSSHQRKGSLMAPHVLKVHGSSWPAELIELCQMADAKLLKGEIEVPDTWNSGDIYLSSKTIKALQGTIGAIETGVDSIFKGPSAEHISNRAFVAIRPPGHHCHYGTPSGFCLLNNAHVAIEYAYDTYNVTHVVVLDFDLHHGDGTQDICWKRAGFKPEEEPEDSSYDDFGKKFAEFPKVGYFSMHDINSFPTESGFATKENIKNASTCIMNSHDLNIWNIHLSKWTTEEEFNVLYRTKYRTLFAKADEFFRSAKLEMNQQGRPFKGLVVISAGFDASEFEQTSMQRHSVNVPTSFYTTFTKDALKLAQMHCHGKVLSLMEGGYSDKAICSGVFAHLIGLQNQDWVKEWGSEQVVKEIVRGCKPAWKPYKTKRAKDVIRIWAEEVIRLGRAMIPEFDDIIFKDAVNSAPSNSLLKATVEPASTSTIAQRIIRSHRSNASPEKELHENKPRSTEKQEQREIRSDTKVKQLSSNNRAAETQIPFLQQEFSSEDEDEEYVYDEELNKTFNRTVEDITIDDISRHLETLEIEKKGDEDSDHELKEKNWKNSHQRRLQGNGMYKIPSNTKPHRIRQPQNANTPTYDDSDISMISHVSRKHTTRSGGRW
xref: UnificationXref uniprot knowledgebase Q02959
xref: RelationshipXref go GO 0005634
xref: RelationshipXref sgd S000006037
xref: RelationshipXref interpro IPR023801
xref: RelationshipXref refseq NP 015209 1
xref: RelationshipXref interpro IPR000286
xref: RelationshipXref go GO 0006351
xref: RelationshipXref go GO 0004407
xref: RelationshipXref intact EBI-8484 identity
xref: RelationshipXref interpro IPR023696
xref: RelationshipXref go GO 0045944
xref: RelationshipXref mint Q02959
xref: RelationshipXref go GO 0016575
xref: RelationshipXref dip DIP-8047N
xref: RelationshipXref uniprotkb D6W3Q2 secondary-ac
xref: RelationshipXref go GO 0032041
xref: RelationshipXref go GO 0000083
xref: RelationshipXref interpro IPR037138
organism: http://identifiers.org/taxonomy/559292
name: HOS3
name: YPL116W
name: LPH11W
name: Histone deacetylase HOS3

Evidence b7bde80f-b10c-4689-ba10-6cc2ddbeaed7 IM-15332-1579 431341 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpd3_yeast
type: Protein
evidence: Evidence 5bdc3c05-9531-4897-9aba-af6a999590bc p 433351
entity reference: rpd3_yeast
name: Histone deacetylase RPD3
comment: psi-mi participant
data source: intact

rpd3_yeast
type: Protein
evidence: Evidence 548d06ff-12d3-40fb-9db9-e2321c888988 p 433346
entity reference: rpd3_yeast
name: Histone deacetylase RPD3
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-11245 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-11245
db: imex

Evidence e2142d53-24e6-4163-af66-3c71db56177b IM-15332-10450 433173 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpd3_yeast
type: Protein
evidence: Evidence 50f1dd28-335b-46aa-be33-a4498b0e2328 p 433334
entity reference: rpd3_yeast
name: Histone deacetylase RPD3
comment: psi-mi participant
data source: intact

UnificationXref uniprot knowledgebase P23293
type: UnificationXref
id: P23293
db: uniprot knowledgebase

RelationshipXref rcsb pdb 5T62
type: RelationshipXref
id: 5T62
db: protein data bank

ExperimentalForm 9d53b135-808e-4dca-9e58-95fc09d2eabc
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpac2_yeast
type: Protein
evidence: Evidence 9787f840-beb1-4c20-8561-503ff1097b19 p 432826
entity reference: P28000
name: DNA-directed RNA polymerases I and III subunit RPAC2
comment: psi-mi participant
data source: intact

UnificationXref uniprot knowledgebase P53982
type: UnificationXref
id: P53982
db: uniprot knowledgebase

RelationshipXref imex IM-15332-12049 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12049
db: imex

UnificationXref mint MINT-2206105
type: UnificationXref
id: MINT-2206105
db: mint

rpd3_yeast
type: Protein
evidence: Evidence 56b7fcba-8292-4686-b75f-227426b06bd5 p 433330
entity reference: rpd3_yeast
name: Histone deacetylase RPD3
comment: psi-mi participant
data source: intact

ExperimentalForm 308cc8a3-0ae5-405f-acc2-96966ae9e9d7
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpd3_yeast
type: Protein
evidence: Evidence ea5e489f-2220-4dc6-8538-97c805d44424 p 433322
entity reference: rpd3_yeast
name: Histone deacetylase RPD3
comment: psi-mi participant
data source: intact

rpd3_yeast
type: Protein
evidence: Evidence d8a5ad61-0042-45a9-96bb-bc22923968d0 p 433319
entity reference: rpd3_yeast
name: Histone deacetylase RPD3
comment: psi-mi participant
data source: intact

rpd3_yeast
type: Protein
evidence: Evidence 89806f96-fb45-4c76-bf76-e256d664d0a7 p 433315
entity reference: rpd3_yeast
name: Histone deacetylase RPD3
comment: psi-mi participant
data source: intact

RelationshipXref sgd S000002563
type: RelationshipXref
id: S000002563
db: sgd

RelationshipXref intact EBI-7524806 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7524806
db: intact

RelationshipXref imex IM-15332-4408 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-4408
db: imex

rpac2_yeast
type: Protein
evidence: Evidence d23e9d7e-7816-41af-879a-1d1daab2ecf8 p 432847
entity reference: P28000
name: DNA-directed RNA polymerases I and III subunit RPAC2
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2195429
type: UnificationXref
id: MINT-2195429
db: mint

ExperimentalForm c23df4b5-62b2-4238-a11c-df624c70c08c
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rfc1-rfc3-3
type: MolecularInteraction
xref: UnificationXref mint MINT-2197502
xref: RelationshipXref imex IM-15332-1574 imex-primary
xref: RelationshipXref intact EBI-7517596 identity
evidence: Evidence 836636b9-6d18-4c93-a0ff-851bce326f4b IM-15332-1574 430889 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.989
comment: author-confidence:z-score: -0.100750888158095
comment: comment:mint
data source: intact
participant: Protein uniprotkb P38630 identity 1529029541848
participant: Protein uniprotkb P38629 identity 1529029541849

rpd3-mtc1-5
type: MolecularInteraction
xref: UnificationXref mint MINT-2208716
xref: RelationshipXref intact EBI-7538424 identity
xref: RelationshipXref imex IM-15332-8822 imex-primary
evidence: Evidence 50d1493d-d4a4-45f0-a85d-8d4c975f6564 IM-15332-8822 433369 430156
interaction type: physical association
comment: author-confidence:z-score: 6.51137996343954
comment: author-confidence:reliability score: 0.77
comment: comment:mint
data source: intact
participant: mtc1_yeast
participant: rpd3_yeast

rpc17-rpc82
type: MolecularInteraction
xref: UnificationXref mint MINT-2205475
xref: RelationshipXref imex IM-15332-813 imex-primary
xref: RelationshipXref intact EBI-7532049 identity
evidence: Evidence 543c52f1-eb70-467b-8871-a85d8956cdd5 IM-15332-813 432649 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.989
comment: comment:mint
comment: author-confidence:z-score: 5.61052108235783
data source: intact
participant: rpc9_yeast
participant: Protein uniprotkb P32349 identity 1529029542728

tho2-hpr1-11
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-8018 imex-primary
xref: RelationshipXref intact EBI-7519394 identity
xref: UnificationXref mint MINT-2198906
evidence: Evidence ff65f058-2509-4c11-8273-ee2514886030 IM-15332-8018 431201 430156
interaction type: physical association
comment: comment:mint
comment: author-confidence:reliability score: 0.99
comment: author-confidence:z-score: 0.162563631831996
data source: intact
participant: Protein uniprotkb P53552 identity 1529029542004
participant: Protein uniprotkb P17629 identity 1529029542005

ExperimentalForm f43c4965-560d-443a-a5e6-636cdc45cae9
type: ExperimentalForm
experimental feature: ModificationFeature 7c34327c-663b-4ea1-b91a-b57e5c3d4d45 431671
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpd3_yeast
type: Protein
evidence: Evidence 4db30637-6b77-4f58-bae6-456aeca10c57 p 433310
entity reference: rpd3_yeast
name: Histone deacetylase RPD3
comment: psi-mi participant
data source: intact

rpd3_yeast
type: Protein
evidence: Evidence c029e7cb-d88d-44a0-9413-6131687a8a7e p 433306
entity reference: rpd3_yeast
name: Histone deacetylase RPD3
comment: psi-mi participant
data source: intact

Evidence 6667a237-e06d-4acb-a3da-0e0845eab6b3 IM-15332-9206 432069 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpd3_yeast
type: Protein
evidence: Evidence a3ea9a8e-82b8-4421-9fc3-de64567cd058 p 433302
entity reference: rpd3_yeast
name: Histone deacetylase RPD3
comment: psi-mi participant
data source: intact

rpd3_yeast
type: Protein
evidence: Evidence 487c4d42-dd24-4ba4-b727-7ee32f3de4d6 p 433299
entity reference: rpd3_yeast
name: Histone deacetylase RPD3
comment: psi-mi participant
data source: intact

RelationshipXref go GO 0008865
type: RelationshipXref
id: GO:0008865
db: gene ontology

ExperimentalForm 21a26c15-a138-4adf-ae60-6157fc54985a
type: ExperimentalForm
experimental feature: ModificationFeature c5643e82-fa20-4d35-b782-5b335d4ee5da 432923
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpd3_yeast
type: Protein
evidence: Evidence 26aa726f-01d2-466b-99d1-031d65903a82 p 433294
entity reference: rpd3_yeast
name: Histone deacetylase RPD3
comment: psi-mi participant
data source: intact

RelationshipXref interpro IPR004480
type: RelationshipXref
id: IPR004480
db: interpro

ExperimentalForm ff7df689-895d-4855-8ad2-5a846b6fe81a
type: ExperimentalForm
experimental feature: ModificationFeature e4c5a2e0-f650-44a0-9fd6-02604a485750 430947
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-10451 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-10451
db: imex

RelationshipXref rcsb pdb 5D0X
type: RelationshipXref
id: 5D0X
db: protein data bank

RelationshipXref uniprotkb P05741 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: P05741
db: uniprot knowledgebase

UnificationXref mint MINT-2205114
type: UnificationXref
id: MINT-2205114
db: mint

Evidence c83410e8-3c7a-4408-9be8-0b571c008a17 IM-15332-2742 431609 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

Evidence 1c928dc0-8f16-413c-bf64-0eb9be0edbd6 IM-15332-4396 432341 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref reactome R-SCE-5218921
type: RelationshipXref
id: R-SCE-5218921
db: reactome

UnificationXref mint MINT-2195057
type: UnificationXref
id: MINT-2195057
db: mint

nap1_yeast
type: Protein
evidence: Evidence c3ca10a8-215c-48d1-9691-e2ae60163adc p 433612
entity reference: nap1_yeast
name: Nucleosome assembly protein
comment: psi-mi participant
data source: intact

rpd3_yeast
type: Protein
evidence: Evidence 5114f819-cb52-45cb-ab9b-2efde5fcb3dd p 433291
entity reference: rpd3_yeast
name: Histone deacetylase RPD3
comment: psi-mi participant
data source: intact

rpd3_yeast
type: Protein
evidence: Evidence 71e68deb-a0ca-4994-8a33-afc52acc0fdf p 433287
entity reference: rpd3_yeast
name: Histone deacetylase RPD3
comment: psi-mi participant
data source: intact

RelationshipXref mint P02994
type: RelationshipXref
id: P02994
db: mint

rpd3_yeast
type: Protein
evidence: Evidence b55a395f-84e0-4b1a-a192-59bbfc20811b p 433283
entity reference: rpd3_yeast
name: Histone deacetylase RPD3
comment: psi-mi participant
data source: intact

rpc9_yeast
type: ProteinReference
sequence: MKVLEERNAFLSDYEVLKFLTDLEKKHLWDQKSLAALKKSRSKGKQNRPYNHPELQGITRNVVNYLSINKNFINQEDEGEERESSGAKDAEKSGISKMSDESFAELMTKLNSFKLFKAEKLQIVNQLPANMVHLYSIVEECDARFDEKTIEEMLEIISGYA
xref: RelationshipXref go GO 0000166
xref: RelationshipXref refseq NP 012523 2
xref: RelationshipXref interpro IPR038324
xref: RelationshipXref go GO 0003899
xref: UnificationXref uniprot knowledgebase P47076
xref: RelationshipXref go GO 0042797
xref: RelationshipXref go GO 0005654
xref: RelationshipXref rcsb pdb 5FJA
xref: RelationshipXref rcsb pdb 6F44
xref: RelationshipXref rcsb pdb 6F42
xref: RelationshipXref rcsb pdb 6F41
xref: RelationshipXref rcsb pdb 6F40
xref: RelationshipXref rcsb pdb 5FJ8
xref: RelationshipXref uniprotkb D6VWG6 secondary-ac
xref: RelationshipXref intact EBI-25782 identity
xref: RelationshipXref sgd S000003548
xref: RelationshipXref mint P47076
xref: RelationshipXref dip DIP-6745N
xref: RelationshipXref interpro IPR010997
xref: RelationshipXref go GO 0005634
xref: RelationshipXref rcsb pdb 6EU3
xref: RelationshipXref rcsb pdb 5FJ9
xref: RelationshipXref rcsb pdb 6EU1
xref: RelationshipXref rcsb pdb 6EU0
xref: RelationshipXref interpro IPR005574
xref: RelationshipXref rcsb pdb 2CKZ
xref: RelationshipXref go GO 0006386
xref: RelationshipXref go GO 0006384
xref: RelationshipXref go GO 0005666
xref: RelationshipXref rcsb pdb 6EU2
xref: RelationshipXref go GO 0005829
organism: http://identifiers.org/taxonomy/559292
name: J1349
name: RPC17
name: DNA-directed RNA polymerase III subunit RPC9
name: RNA polymerase III subunit C17
name: YJL011C

rpd3_yeast
type: Protein
evidence: Evidence 37ace713-b535-450b-9a45-3bb973df5c2c p 433278
entity reference: rpd3_yeast
name: Histone deacetylase RPD3
comment: psi-mi participant
data source: intact

rpd3_yeast
type: Protein
evidence: Evidence 884f1491-2fb6-4a37-bb09-3e5ff17ff8f6 p 433274
entity reference: rpd3_yeast
name: Histone deacetylase RPD3
comment: psi-mi participant
data source: intact

RelationshipXref sgd S000002544
type: RelationshipXref
id: S000002544
db: sgd

ExperimentalForm ce69e9f9-7454-4a93-b4c9-f5e336faa72b
type: ExperimentalForm
experimental feature: ModificationFeature d9db93b9-0f98-440b-ba5f-768791a8ec76 430787
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm bd80da23-81c0-4938-a503-a3fc328b0f56
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7532920 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7532920
db: intact

RelationshipXref refseq NP 015513 1
type: RelationshipXref
id: NP_015513.1
db: refseq

top2_yeast
type: Protein
evidence: Evidence 47a9b830-c58b-45df-8c99-fca37c393738 p 430426
entity reference: top2_yeast
name: DNA topoisomerase 2
comment: psi-mi participant
data source: intact

RelationshipXref mint P23643
type: RelationshipXref
id: P23643
db: mint

RelationshipXref go GO 0042645
type: RelationshipXref
id: GO:0042645
db: gene ontology

ExperimentalForm d23f26fc-c012-4789-b679-5bf9fea58d5e
type: ExperimentalForm
experimental feature: ModificationFeature 298c7fce-7911-4707-882f-390c4a800e37 431627
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 2bd190ce-b92d-43c5-94d0-13568a8fb826
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

Evidence 020d7ba1-5369-48f7-a3ac-dce9cfc897f2 IM-15332-3584 431661 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm 345748a7-e67d-4066-a099-0527ce93ab65
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref mint P38629
type: RelationshipXref
id: P38629
db: mint

ExperimentalForm 949cae9c-f43f-40dd-a996-152028d0949a
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7535933 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7535933
db: intact

RelationshipXref imex IM-15332-4785 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-4785
db: imex

RelationshipXref uniprotkb Q7Z8Q9 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: Q7Z8Q9
db: uniprot knowledgebase

Evidence f6365fc2-2718-4a99-848a-1f9117a317f4 IM-15332-12053 431965 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref mint MINT-2195075
type: UnificationXref
id: MINT-2195075
db: mint

rpn1-rpt2-15
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-10865 imex-primary
xref: UnificationXref mint MINT-2210696
xref: RelationshipXref intact EBI-7542692 identity
evidence: Evidence 2f87ed91-573e-4870-aade-63e93d750e1c IM-15332-10865 433809 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: -0.152181057559982
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P38764 identity 1529029543309
participant: prs4_yeast

RelationshipXref imex IM-15332-9602 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-9602
db: imex

UnificationXref mint MINT-2197032
type: UnificationXref
id: MINT-2197032
db: mint

ExperimentalForm 916743d2-959d-4777-b242-fd765b43481d
type: ExperimentalForm
experimental feature: ModificationFeature 33708545-cc43-4cf3-afd2-2cdcb316dd6f 431363
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpa14_yeast
type: Protein
evidence: Evidence 620313c3-ac6c-42cf-b591-2b1fe361c51b p 431594
entity reference: P50106
name: DNA-directed RNA polymerase I subunit RPA14
comment: psi-mi participant
data source: intact

rpb8-rpb4
type: MolecularInteraction
xref: RelationshipXref intact EBI-7529280 identity
xref: UnificationXref mint MINT-2204201
xref: RelationshipXref imex IM-15332-5179 imex-primary
evidence: Evidence a285b964-c659-4c24-afef-d70dd77e7092 IM-15332-5179 432377 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:z-score: 9.40589984302941
comment: author-confidence:reliability score: 0.676
data source: intact
participant: Protein uniprotkb P20436 identity 1529029542593
participant: Protein uniprotkb P20433 identity 1529029542592

rpc40-rpc17-1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-9210 imex-primary
xref: UnificationXref mint MINT-2207222
xref: RelationshipXref intact EBI-7535194 identity
evidence: Evidence 4029cc99-dd4c-40f5-a0ba-5f0d5b8160af IM-15332-9210 433037 430156
interaction type: physical association
comment: comment:mint
comment: author-confidence:reliability score: 0.99
comment: author-confidence:z-score: 0.714570233405571
data source: intact
participant: rpc9_yeast
participant: Protein uniprotkb P07703 identity 1529029542923

RelationshipXref intact EBI-15835 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-15835
db: intact

rpab1_yeast
type: Protein
evidence: Evidence 916abaf4-3ac5-410f-b291-c99e649077c8 p 432374
entity reference: rpab1_yeast
name: DNA-directed RNA polymerases I, II, and III subunit RPABC1
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-15270 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-15270
db: intact

ExperimentalForm 7b68c43d-c273-4d80-8f16-8af01df2ce96
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref go GO 0042623
type: RelationshipXref
id: GO:0042623
db: gene ontology

RelationshipXref reactome R-SCE-5357572
type: RelationshipXref
id: R-SCE-5357572
db: reactome

RelationshipXref mint P22276
type: RelationshipXref
id: P22276
db: mint

RelationshipXref go GO 0008821
type: RelationshipXref
id: GO:0008821
db: gene ontology

rpa190-rpa135-2
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-5173 imex-primary
xref: RelationshipXref intact EBI-7522481 identity
xref: UnificationXref mint MINT-2200832
evidence: Evidence 180cab01-fdad-4bb1-8347-d9d4442e2d97 IM-15332-5173 431629 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 0.648236168750988
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: rpa1_yeast
participant: Protein uniprotkb P22138 identity 1529029542219

rgp1-ric1-1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-11237 imex-primary
xref: RelationshipXref intact EBI-7518234 identity
xref: UnificationXref mint MINT-2197916
evidence: Evidence 859e243a-ab8e-424e-a563-46e39157aa30 IM-15332-11237 430981 430156
interaction type: physical association
comment: author-confidence:z-score: 4.42317416900892
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P16664 identity 1529029541895
participant: Protein uniprotkb P40395 identity 1529029541894

RelationshipXref interpro IPR003094
type: RelationshipXref
id: IPR003094
db: interpro

RelationshipXref go GO 0006537
type: RelationshipXref
id: GO:0006537
db: gene ontology

RelationshipXref refseq NP 010440 1
type: RelationshipXref
id: NP_010440.1
db: refseq

RelationshipXref dip DIP-1518N
type: RelationshipXref
id: DIP-1518N
db: database of interacting proteins

ret2-sec26-6
type: MolecularInteraction
xref: UnificationXref mint MINT-2196258
xref: RelationshipXref imex IM-15332-9193 imex-primary
xref: RelationshipXref intact EBI-7516149 identity
evidence: Evidence 4e6a4551-a62e-477e-b124-4b29238a05f9 IM-15332-9193 430613 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.976
comment: comment:mint
comment: author-confidence:z-score: 1.31241124012493
data source: intact
participant: Protein uniprotkb P43621 identity 1529029541710
participant: Protein uniprotkb P41810 identity 1529029541711

net1_yeast
type: ProteinReference
sequence: MYKLQVVLVPPSLQATMPIQFGYGPTIAESSQLLPNRTNMAQSAGDASLQYANLRSANVSFTPSYFNQSRFRKFLLFTKPTNTLLNLSDEIIDKCEKMYPSLQEDIEILSLQDNSGCDLDPDFLVKDVFNVNNIVRVILKNEIDLDDSAPVSLYKSVKRSKLNNGSPQSVQPQQQIPSSSGVLRIAKKRPPTGTTTTTTIRSATNGSMRVSTPLARQIYPPPSSKIVSNNSDDEDEDIGERSFLPPPTQPQSPPIRISSGIDAGKKIKSSIVEEDIVSRSATVDPDKTKQQRLLSGTPIMSTMTPNRVTLTGQRVVSEHAHKNELVFSASASSSSFANGGTAAVTAQDINRKPPVTTPRITSGMLKIPEPRISEIEKELKEGPSSPASILPAKAAKIPMKKPYLENGENYESDDSSSSENQETPETEPHSKASLQRSQSSIADNNGSPVKNSPLGDAMPHNVHLAELPKASNTSITKSSNGESWGKQQEHQPPRKSSLETIVEKKSQAEPSGIVEPKRMTNFLDDNQVREKEDTNDKLLEKEILPTIPHNDQPILASSDKSNGTLKSLAGKVSSNNNASKEDGTIINGTIEDDGNDNDEVDTTVRIVPQDSDSSSFPKSDLFKMIEGDDTDLPQWFKGKNSRTSGNSKNSKPYTTVLNKDIDNSKPDPRNILPQRTPRSAAKRAAQLLAGAKKNEVPQKSTEDSSSAASTDDESESGIETDFSSDDDFKRKNMSVPNNGPKDISLHSLKGSVVPVKDSKIINKEVDEERNDKRDSQKKSAVSESSVTNSKISEQMAKSFYPNSNKKQNEATKVETKPATQASSFPVVGGSPSVATKGTTSFNEEGNRKNVKTKAKNESAQIDRQQKETTSRVADLKSANIGGEDLNKKAEGSKEPEKASANIQDANDKNNSKEKEDSKSKQVSQKKLKMTDHLKEGNVQLPKPSANDKLKDLKAKFTNSKTLVPPGIISNEKNNSSANDDDSSSSGSSTEDESSSSSSSSDEETSTSRKARRVVVNTPREPVRSSSKIEAPSPSVNKKINATPDKIPVTQLMDMSSPPSVKSKTTSNPSSILHDLPRKVRPSLSSLSDLVSRGIPDVKEKTSKSNEKSQTKAPSSSDDESSSDSDSNSSSDSVSDSSSDSKSESDSDDSGDSSDDGKSFISAKSASAALGKKKKPSGGFASLIKDFKKK
xref: RelationshipXref sgd S000003612
xref: RelationshipXref go GO 0007096
xref: RelationshipXref mint P47035
xref: RelationshipXref go GO 0031030
xref: RelationshipXref go GO 0007000
xref: RelationshipXref dip DIP-5153N
xref: RelationshipXref go GO 0030869
xref: RelationshipXref go GO 0000183
xref: RelationshipXref go GO 0000182
xref: RelationshipXref uniprotkb D6VWA8 secondary-ac
xref: RelationshipXref go GO 0019211
xref: UnificationXref uniprot knowledgebase P47035
xref: RelationshipXref refseq NP 012459 1
xref: RelationshipXref intact EBI-25953 identity
xref: RelationshipXref go GO 0005730
xref: RelationshipXref interpro IPR018844
organism: http://identifiers.org/taxonomy/559292
name: J1038
name: YJL076W
name: CFI1
name: NET1
name: ESC5
name: Nucleolar protein NET1
name: SRM8

ExperimentalForm c9c7e922-2324-4443-9755-ff8bad08de85
type: ExperimentalForm
experimental feature: ModificationFeature 4f192583-8a0e-40bd-9529-d73818202bc8 433887
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpn1-rpt4-7
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-7654 imex-primary
xref: UnificationXref mint MINT-2210552
xref: RelationshipXref intact EBI-7542452 identity
evidence: Evidence e2908040-10f9-4902-88a2-dfffcbc17756 IM-15332-7654 433777 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.93
comment: comment:homomint
comment: author-confidence:z-score: 0.162699951310543
comment: comment:mint
data source: intact
participant: Protein uniprotkb P38764 identity 1529029543292
participant: prs10_yeast

ExperimentalForm f17c1b5a-6f6d-40ec-a264-e488bf435576
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 683ae113-e371-4e9f-9b41-61c5eb32dfc5
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 0c5b4872-029a-4989-b58c-3e2444f3f50f
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rfa2-rfa1-7
type: MolecularInteraction
xref: RelationshipXref intact EBI-7517254 identity
xref: UnificationXref mint MINT-2197177
xref: RelationshipXref imex IM-15332-1572 imex-primary
evidence: Evidence cfb42b84-b8c1-46ee-979d-15d1041b20be IM-15332-1572 430817 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 2.15668552110819
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P26754 identity 1529029541812
participant: rfa1_yeast

RelationshipXref imex IM-15332-8411 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-8411
db: imex

UnificationXref mint MINT-2209652
type: UnificationXref
id: MINT-2209652
db: mint

ExperimentalForm a7197b66-178f-4dba-b251-97a487da11d5
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpab1_yeast
type: Protein
evidence: Evidence 8657771c-e8d6-4e76-97c3-0a12bec1a12a p 432323
entity reference: rpab1_yeast
name: DNA-directed RNA polymerases I, II, and III subunit RPABC1
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-7631 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-7631
db: imex

RelationshipXref rcsb pdb 3KX2
type: RelationshipXref
id: 3KX2
db: protein data bank

rpg1-nip1-4
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-4794 imex-primary
xref: UnificationXref mint MINT-2208914
xref: RelationshipXref intact EBI-7538842 identity
evidence: Evidence 691bc7ae-a4f5-4b0f-92ab-9af69ec3918c IM-15332-4794 433413 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 6.0772900812505
comment: comment:mint
comment: author-confidence:reliability score: 0.968
data source: intact
participant: Protein uniprotkb P32497 identity 1529029543110
participant: Protein uniprotkb P38249 identity 1529029543111

RelationshipXref imex IM-15332-8435 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-8435
db: imex

rpc40-rpa49-2
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-7207 imex-primary
xref: RelationshipXref intact EBI-7535949 identity
xref: UnificationXref mint MINT-2207582
evidence: Evidence 294636b0-ee58-4837-acd3-8df4553a094a IM-15332-7207 433117 430156
interaction type: physical association
comment: author-confidence:z-score: 9.39614162710684
comment: comment:homomint
comment: author-confidence:reliability score: 0.983
comment: comment:mint
data source: intact
participant: Protein uniprotkb P07703 identity 1529029542962
participant: Protein uniprotkb Q01080 identity 1529029542963

rpc40-rpa43-1
type: MolecularInteraction
xref: UnificationXref mint MINT-2207204
xref: RelationshipXref imex IM-15332-6385 imex-primary
xref: RelationshipXref intact EBI-7535156 identity
evidence: Evidence e9033d48-7cf3-4ea5-87ac-e2994d4fa901 IM-15332-6385 433033 430156
interaction type: physical association
comment: author-confidence:z-score: 7.95035575369033
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P07703 identity 1529029542921
participant: rpa43_yeast

mtc1_yeast
type: ProteinReference
sequence: MSENKNSEAEDVFEFLDSLPEAKNGGKMVNTDVKGSQEGVKGGSNSVAGKTGNDGKKGDDDIFEFLEELEKSNLSLTDKKGVEKKAPSESVNNKAQDEKVEESKENKNSEQDAHGKEKEPQQQEKEEEEEEEEEEEEEEEETPLHDPIASISNWWSSSGSAKVSSIWNKTAEQASQIKNRLAQEQLDLTSKINTSTITEIARNLQKIVVGETEEVLRIHLVHDLVNYPSLQYNIESKFDQVLSSQVEGGIRIFVDEWGHPNNNGITPVEKKPSVADGELGNSKKKLQFNLFDGKVTDGEKLAFANLENAVKLFNTAHEEYQKQQKEADATPDDDRSSISSNSNKISDLFISILPIAIPQKQKDADGDFQVTDSNTPGNFNFTLVLKDITNDITTITRSQGFPVKWVNWLEGSVEKTGSTASEERNKSYDQKKQKESEDEDEDDEIIDPSEWVKEWIEDGLSLSFGVMAQNYVIDRMGL
xref: RelationshipXref sgd S000003659
xref: RelationshipXref uniprotkb D6VW63 secondary-ac
xref: RelationshipXref mint P47018
xref: RelationshipXref go GO 0030137
xref: RelationshipXref refseq NP 012412 1
xref: UnificationXref uniprot knowledgebase P47018
xref: RelationshipXref interpro IPR018814
xref: RelationshipXref intact EBI-26065 identity
organism: http://identifiers.org/taxonomy/559292
name: J0718
name: YJL123C
name: MTC1
name: Maintenance of telomere capping protein 1

ExperimentalForm 814014c2-22b1-4db8-aaa0-28aa19210c63
type: ExperimentalForm
experimental feature: ModificationFeature b401c3be-ca7e-4ec5-ba98-fc585d935eea 432648
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpab1_yeast
type: Protein
evidence: Evidence 49c5ccef-1081-42d2-8685-f1e603c2488d p 432304
entity reference: rpab1_yeast
name: DNA-directed RNA polymerases I, II, and III subunit RPABC1
comment: psi-mi participant
data source: intact

Evidence 5bcec531-7a9d-42a9-9fb0-76d260cf1618 IM-15332-10445 432521 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpa135-rpa190
type: MolecularInteraction
xref: RelationshipXref intact EBI-7521747 identity
xref: RelationshipXref imex IM-15332-12874 imex-primary
xref: UnificationXref mint MINT-2200364
evidence: Evidence 264f1943-8316-4ace-a108-308f9ac63ee3 IM-15332-12874 431525 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 0.099081704039812
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P22138 identity 1529029542167
participant: Protein uniprotkb P10964 identity 1529029542166

RelationshipXref mint Q12263
type: RelationshipXref
id: Q12263
db: mint

rpc40-atg11-1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-10451 imex-primary
xref: RelationshipXref intact EBI-7536493 identity
xref: UnificationXref mint MINT-2208014
evidence: Evidence 75405179-3618-4536-9481-e2b0b726acec IM-15332-10451 433213 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.425
comment: author-confidence:z-score: 0.087439210037324
comment: comment:mint
data source: intact
participant: Protein uniprotkb P07703 identity 1529029543011
participant: atg11_yeast

RelationshipXref uniprotkb D6VSL9 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VSL9
db: uniprot knowledgebase

ExperimentalForm fde47a24-f23a-4feb-8028-d43ac7386e22
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpa34_yeast
type: ProteinReference
sequence: MSKLSKDYVSDSDSDDEVISNEFSIPDGFKKCKHLKNFPLNGDNKKKAKQQQVWLIKFPSNVDISKLKSLPVDFESSTTMTIDKHDYKIMDDTDIESSLTQDNLSNMTLLVPSESKESLKIASTAKDNAPLQFDKVFSVSETAKIPAIDYSKVRVPRKDVPKVEGLKLEHFATGYDAEDFHVAEEVKENKKEPKKRSHHDDEEESSEKKKKKKEKREKREKKDKKDKKKKHRD
xref: RelationshipXref rcsb pdb 5W64
xref: RelationshipXref go GO 0042790
xref: RelationshipXref go GO 0001054
xref: RelationshipXref rcsb pdb 5M3F
xref: RelationshipXref intact EBI-26109 identity
xref: RelationshipXref rcsb pdb 5M5Y
xref: RelationshipXref rcsb pdb 4YM7
xref: RelationshipXref rcsb pdb 5W5Y
xref: RelationshipXref uniprotkb D6VW37 secondary-ac
xref: RelationshipXref rcsb pdb 5W66
xref: RelationshipXref rcsb pdb 5W65
xref: RelationshipXref sgd S000003684
xref: RelationshipXref rcsb pdb 4C3I
xref: RelationshipXref rcsb pdb 4C3H
xref: RelationshipXref rcsb pdb 5M5W
xref: RelationshipXref dip DIP-7973N
xref: UnificationXref uniprot knowledgebase P47006
xref: RelationshipXref rcsb pdb 4C3J
xref: RelationshipXref rcsb pdb 5N5Z
xref: RelationshipXref rcsb pdb 5N5Y
xref: RelationshipXref rcsb pdb 5N60
xref: RelationshipXref rcsb pdb 5OA1
xref: RelationshipXref go GO 0006362
xref: RelationshipXref rcsb pdb 5N61
xref: RelationshipXref go GO 0006360
xref: RelationshipXref rcsb pdb 5LMX
xref: RelationshipXref refseq NP 012387 1
xref: RelationshipXref rcsb pdb 4C2M
xref: RelationshipXref rcsb pdb 5M64
xref: RelationshipXref mint P47006
xref: RelationshipXref interpro IPR013240
xref: RelationshipXref go GO 0005634
xref: RelationshipXref go GO 0042254
xref: RelationshipXref rcsb pdb 5G5L
xref: RelationshipXref go GO 0005736
xref: RelationshipXref rcsb pdb 5M3M
xref: RelationshipXref rcsb pdb 5M5X
xref: RelationshipXref go GO 0005730
organism: http://identifiers.org/taxonomy/559292
name: RPA34
name: J0637
name: YJL148W
name: DNA-directed RNA polymerase I subunit RPA34
name: DNA-directed DNA-dependent RNA polymerase 34.5 kDa polypeptide

RelationshipXref go GO 0006099
type: RelationshipXref
id: GO:0006099
db: gene ontology

ExperimentalForm 451ac436-a3ce-406f-8ff4-5251491ef3bb
type: ExperimentalForm
experimental feature: ModificationFeature b53140bc-7691-48e4-91e3-865b5aa58bae 430507
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref go GO 0006096
type: RelationshipXref
id: GO:0006096
db: gene ontology

ExperimentalForm d60e1e1c-5cd3-44f4-9a6e-192a0bc28d68
type: ExperimentalForm
experimental feature: ModificationFeature 9f562a2a-5708-4308-b611-2174b63cb0a1 432271
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref uniprotkb D6W0V7 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6W0V7
db: uniprot knowledgebase

RelationshipXref intact EBI-7535639 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7535639
db: intact

rpb3_yeast
type: Protein
evidence: Evidence 4291ee38-2599-48b0-be47-d81ac53ed5af p 432295
entity reference: P16370
name: DNA-directed RNA polymerase II subunit RPB3
comment: psi-mi participant
data source: intact

RelationshipXref mint Q12250
type: RelationshipXref
id: Q12250
db: mint

rpb3_yeast
type: Protein
evidence: Evidence 401dd59f-ed31-43ae-af1d-671fc0bd569a p 432302
entity reference: P16370
name: DNA-directed RNA polymerase II subunit RPB3
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-7641 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-7641
db: imex

RelationshipXref mint P38431
type: RelationshipXref
id: P38431
db: mint

RelationshipXref imex IM-15332-12869 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12869
db: imex

Evidence 26e6ab6d-8a59-4fcd-8098-f13113371708 IM-15332-4768 431101 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref interpro IPR019258
type: RelationshipXref
id: IPR019258
db: interpro

RelationshipXref intact EBI-7539134 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7539134
db: intact

rpb8-yp225-9
type: MolecularInteraction
xref: UnificationXref mint MINT-2204165
xref: RelationshipXref intact EBI-7529168 identity
xref: RelationshipXref imex IM-15332-8815 imex-primary
evidence: Evidence e967588d-a722-48a4-8818-1d5caad41f3a IM-15332-8815 432369 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.989
comment: comment:mint
comment: author-confidence:z-score: 9.5789867541917
data source: intact
participant: Protein uniprotkb Q08971 identity 1529029542588
participant: Protein uniprotkb P20436 identity 1529029542589

UnificationXref mint MINT-2208896
type: UnificationXref
id: MINT-2208896
db: mint

RelationshipXref interpro IPR037685
type: RelationshipXref
id: IPR037685
db: interpro

RelationshipXref uniprotkb D6VZ67 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VZ67
db: uniprot knowledgebase

RelationshipXref dip DIP-1890N
type: RelationshipXref
id: DIP-1890N
db: database of interacting proteins

ExperimentalForm 2652ff27-316d-4264-aa31-c43a03efa53d
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

atg11_yeast
type: Protein
evidence: Evidence a774bba5-2e5e-46c8-a611-b9f9370f6d92 p 433214
entity reference: atg11_yeast
name: Autophagy-related protein 11
comment: psi-mi participant
data source: intact

RelationshipXref uniprotkb D6VVQ8 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VVQ8
db: uniprot knowledgebase

RelationshipXref go GO 0071902
type: RelationshipXref
id: GO:0071902
db: gene ontology

RelationshipXref rcsb pdb 3L4K
type: RelationshipXref
id: 3L4K
db: protein data bank

RelationshipXref rcsb pdb 3L4J
type: RelationshipXref
id: 3L4J
db: protein data bank

ExperimentalForm d01dd365-d605-4575-a597-efd9261546b2
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

Evidence d535fa6f-0ed9-49ec-963e-11abda57df5d IM-15332-5602 433837 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rfa1-rfa2-6
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-4385 imex-primary
xref: UnificationXref mint MINT-2196816
xref: RelationshipXref intact EBI-7516869 identity
evidence: Evidence 882ae88d-5337-4230-80ca-a4b09fc5c2b4 IM-15332-4385 430737 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 6.89709199043275
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: rfa1_yeast
participant: Protein uniprotkb P26754 identity 1529029541772

RelationshipXref mint Q12230
type: RelationshipXref
id: Q12230
db: mint

RelationshipXref sgd S000001100
type: RelationshipXref
id: S000001100
db: sgd

rpb3_yeast
type: Protein
evidence: Evidence b6c0866a-80df-4538-b63c-44b6e2f417dc p 432319
entity reference: P16370
name: DNA-directed RNA polymerase II subunit RPB3
comment: psi-mi participant
data source: intact

RelationshipXref dip DIP-6755N
type: RelationshipXref
id: DIP-6755N
db: database of interacting proteins

UnificationXref mint MINT-2202759
type: UnificationXref
id: MINT-2202759
db: mint

UnificationXref mint MINT-2208878
type: UnificationXref
id: MINT-2208878
db: mint

rpd3-mtc1-7
type: MolecularInteraction
xref: UnificationXref mint MINT-2208752
xref: RelationshipXref intact EBI-7538474 identity
xref: RelationshipXref imex IM-15332-12497 imex-primary
evidence: Evidence f5ad091d-ff54-4698-b949-cc84ce795275 IM-15332-12497 433377 430156
interaction type: physical association
comment: author-confidence:z-score: 5.61515493597214
comment: comment:mint
comment: author-confidence:reliability score: 0.77
data source: intact
participant: Protein uniprotkb P47018 identity 1529029543093
participant: rpd3_yeast

ExperimentalForm 8ebb9abb-8a15-457f-bbed-ab5ddc5c1319
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref go GO 0000781
type: RelationshipXref
id: GO:0000781
db: gene ontology

ExperimentalForm 3b06e8bd-c6b9-4e6f-a046-ace2549d15c9
type: ExperimentalForm
experimental feature: ModificationFeature 58e83c41-6882-431b-aa46-383af1a4327d 432459
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-5166 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5166
db: imex

Evidence 5212a455-a4bf-44ab-9602-36063913d703 IM-15332-818 433769 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref intact EBI-8555 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-8555
db: intact

rpab1_yeast
type: Protein
evidence: Evidence 6c85cb13-e3ed-4818-8447-7eba87a1c41f p 432204
entity reference: rpab1_yeast
name: DNA-directed RNA polymerases I, II, and III subunit RPABC1
comment: psi-mi participant
data source: intact

ExperimentalForm 5476d0fb-3516-4d98-8acc-93bef3b52d3c
type: ExperimentalForm
experimental feature: ModificationFeature 35595df4-7394-41f2-9aff-57b5e079d1c9 432612
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

UnificationXref uniprot knowledgebase Q07381
type: UnificationXref
id: Q07381
db: uniprot knowledgebase

RelationshipXref imex IM-15332-1949 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1949
db: imex

rpb10-rpb2-6
type: MolecularInteraction
xref: UnificationXref mint MINT-2202939
xref: RelationshipXref intact EBI-7525669 identity
xref: RelationshipXref imex IM-15332-6379 imex-primary
evidence: Evidence d7718885-d01e-40e3-b44c-d45fa5fa2251 IM-15332-6379 432097 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.989
comment: comment:mint
comment: author-confidence:z-score: 4.34664863453362
data source: intact
participant: Protein uniprotkb P08518 identity 1529029542453
participant: rpab5_yeast

rpb9-rpb3
type: MolecularInteraction
xref: RelationshipXref intact EBI-7530458 identity
xref: RelationshipXref imex IM-15332-9613 imex-primary
xref: UnificationXref mint MINT-2204546
evidence: Evidence c3c47e04-4922-4bcf-9cf9-1f0a5a43bee4 IM-15332-9613 432449 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.99
comment: author-confidence:z-score: 6.18999671262567
data source: intact
participant: Protein uniprotkb P16370 identity 1529029542628
participant: Protein uniprotkb P27999 identity 1529029542629

UnificationXref mint MINT-2208860
type: UnificationXref
id: MINT-2208860
db: mint

csk21_yeast
type: Protein
evidence: Evidence 017f25ef-cb34-4637-94a3-3c72adceddb4 p 431098
entity reference: csk21_yeast
name: Casein kinase II subunit alpha
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7518234 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7518234
db: intact

Evidence e9033d48-7cf3-4ea5-87ac-e2994d4fa901 IM-15332-6385 433033 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm 5bd4c224-050e-46f6-b274-7883df7f82a3
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref mint MINT-2197862
type: UnificationXref
id: MINT-2197862
db: mint

RelationshipXref interpro IPR029060
type: RelationshipXref
id: IPR029060
db: interpro

RelationshipXref interpro IPR029063
type: RelationshipXref
id: IPR029063
db: interpro

RelationshipXref intact EBI-7540433 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7540433
db: intact

ExperimentalForm ff9086c9-531b-4cef-8a98-81d085b4cd63
type: ExperimentalForm
experimental feature: ModificationFeature 1c14ae11-2aa7-4c4b-b895-91b27ef0302a 430851
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref go GO 2000001
type: RelationshipXref
id: GO:2000001
db: gene ontology

ExperimentalForm f4bc1662-a2ee-4f2a-88a9-f7039e99bbba
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 352e91a1-1203-4d06-8ada-31ef8fdb3d49
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

Evidence 193528ca-c75c-4437-9b8c-f984a9c48442 IM-15332-5972 430733 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

Evidence e07f1557-02ec-42ce-bf67-a750ca52d446 IM-15332-10431 431061 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm eea6b520-1f0c-4d7b-8318-93421cb2fdaa
type: ExperimentalForm
experimental feature: ModificationFeature cd26eb56-1113-457e-b9c3-32c175d38f47 432187
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref dip DIP-1617N
type: RelationshipXref
id: DIP-1617N
db: database of interacting proteins

ExperimentalForm b88018ef-571f-45da-af16-e1e2ab43c2e4
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref imex IM-15332-5176 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5176
db: imex

UnificationXref mint MINT-2208842
type: UnificationXref
id: MINT-2208842
db: mint

RelationshipXref intact EBI-7538185 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7538185
db: intact

RelationshipXref imex IM-15332-10439 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-10439
db: imex

RelationshipXref refseq NP 014040 1
type: RelationshipXref
id: NP_014040.1
db: refseq

RelationshipXref refseq NP 012195 1
type: RelationshipXref
id: NP_012195.1
db: refseq

RelationshipXref imex IM-15332-8821 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-8821
db: imex

ExperimentalForm b82cc5d4-cb2c-4566-b37d-366a4700b245
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 9f7a59c0-0674-44ec-830a-559a023a8d4b
type: ExperimentalForm
experimental feature: ModificationFeature 8fd86bcb-dda9-4864-93eb-ada7d85efb9a 433395
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref mint P16370
type: RelationshipXref
id: P16370
db: mint

RelationshipXref sgd S000000253
type: RelationshipXref
id: S000000253
db: sgd

UnificationXref mint MINT-2202777
type: UnificationXref
id: MINT-2202777
db: mint

RelationshipXref intact EBI-7517292 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7517292
db: intact

ExperimentalForm 674ff43b-2dfb-4719-a3b4-013ff01fcd73
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7540787 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7540787
db: intact

Evidence ef380977-a2a2-4769-b822-410f112ed363 IM-15332-6780 432101 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

Evidence dd404dfc-469f-4f39-9b0d-1aa7bd7736bd IM-15332-2369 433669 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref intact EBI-7532733 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7532733
db: intact

ExperimentalForm e4a0da71-3835-4a43-a04c-c271c31014f6
type: ExperimentalForm
experimental feature: ModificationFeature 35604c91-f32c-422a-b591-b1b0177e7fac 431923
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref uniprotkb D6VQ78 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VQ78
db: uniprot knowledgebase

ExperimentalForm 9d83a6e3-93e7-4ef3-97ac-f2815c9b6300
type: ExperimentalForm
experimental feature: ModificationFeature 3b155b6d-4f0a-49f4-8642-03254b5f8271 431067
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref reactome R-SCE-174113
type: RelationshipXref
id: R-SCE-174113
db: reactome

sld3_yeast
type: ProteinReference
sequence: METWEVIASVKEATKGLDLSLDHPLIIKSEDVPSNILQLLQQKNRRQLKHICMKSRKEYFLLEEYGPGFWVKWPYNYFNGYSLPERRTEVVTTVERERAKRETLKTWDELKFKELLHLWSEEPKGSCKLEKDKDLKLDMNPPDMKGESKINDYYSDPKEYIESKYYDALFSIHTPLAYFVKSNLVRLKNTCRTKYGSDSYKIAYQAMLQKFLLSIVQFKDRHDNRLLLEPFSSPIADEKRKNCLTKFVIQDENKNSSTIADLCVVLKSREIKLQILLLLEIIGLNDLDWNFRDFEKKYKLKLKKRSLNLTKKGLVRRRSKKKTSEKDKGIERITTSLDYCEQLDLYLDRACILDILLSSETPNPDAIEASNGTIQEHKKNILDKSKEASLVGFINYVLIPYFNKKVPHAVEFIIQKLKGPSMRPKRALKKVNDSTNVSSPNTVETYNRLSTSQRASRSSIINSVPSSPALRRVDANLFSRKSIASPTPELLNSRTNSNLNEFLESETRSLKRPSQLGRTKSDLTMNHLQKRQFSVSDLSTTRVPNSSTITLKTPFSHSTINAYKTMNNSFRRVGKRKDINETIRLHERVDSEENVQVQATPAVKKRTVTPNKKAQLQSIIESPLNFKDDDTHEGRKNTSNITSTPTNKPPENSSKRRVRRRLFAPEST
xref: RelationshipXref go GO 0000790
xref: UnificationXref uniprot knowledgebase P53135
xref: RelationshipXref sgd S000003081
xref: RelationshipXref go GO 0031261
xref: RelationshipXref go GO 0000775
xref: RelationshipXref refseq NP 011402 3
xref: RelationshipXref go GO 0006270
xref: RelationshipXref go GO 0007049
xref: RelationshipXref rcsb pdb 3WI3
xref: RelationshipXref uniprotkb D6VU34 secondary-ac
xref: RelationshipXref intact EBI-23925 identity
xref: RelationshipXref go GO 0000727
xref: RelationshipXref go GO 0003682
xref: RelationshipXref dip DIP-5481N
xref: RelationshipXref mint P53135
xref: RelationshipXref interpro IPR013948
xref: RelationshipXref go GO 0006268
organism: http://identifiers.org/taxonomy/559292
name: DNA replication regulator SLD3
name: G2980
name: YGL113W
name: SLD3

RelationshipXref go GO 0006013
type: RelationshipXref
id: GO:0006013
db: gene ontology

ExperimentalForm 65fb59a0-c451-4ec7-a16f-127fc43b7289
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

t2fb_yeast
type: Protein
evidence: Evidence 2c7ee9b4-bacd-4d0f-bde9-2c2729a1f31f p 432306
entity reference: P41896
name: Transcription initiation factor IIF subunit beta
comment: psi-mi participant
data source: intact

Evidence 84234571-e804-4f7f-80a2-cb95801a75d7 IM-15332-10433 431273 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref mint MINT-2208824
type: UnificationXref
id: MINT-2208824
db: mint

RelationshipXref intact EBI-7518531 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7518531
db: intact

rpab1_yeast
type: Protein
evidence: Evidence 3f91bdd6-f11b-4d57-af6a-e722ed9d4bcb p 432704
entity reference: rpab1_yeast
name: DNA-directed RNA polymerases I, II, and III subunit RPABC1
comment: psi-mi participant
data source: intact

rpa43_yeast
type: Protein
evidence: Evidence 7c7f8e3e-b9cf-4211-8387-2b105efab87f p 431584
entity reference: P46669
name: DNA-directed RNA polymerase I subunit RPA43
comment: psi-mi participant
data source: intact

rpa43_yeast
type: Protein
evidence: Evidence 4cf5f9e6-cd43-4f18-b485-f095dffa5ce1 p 431576
entity reference: P46669
name: DNA-directed RNA polymerase I subunit RPA43
comment: psi-mi participant
data source: intact

Evidence 12b46458-5cdb-4369-a558-e59151e3aa8e IM-15332-8427 433009 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm eadf2d98-27a8-475f-a317-0877b06f46ca
type: ExperimentalForm
experimental feature: ModificationFeature ef12e366-7713-4ede-a683-d98cd10679be 430608
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref go GO 0006006
type: RelationshipXref
id: GO:0006006
db: gene ontology

RelationshipXref go GO 0006003
type: RelationshipXref
id: GO:0006003
db: gene ontology

RelationshipXref go GO 0006000
type: RelationshipXref
id: GO:0006000
db: gene ontology

RelationshipXref imex IM-15332-6364 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-6364
db: imex

RelationshipXref intact EBI-7522733 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7522733
db: intact

rpb10-rpo21-8
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-12484 imex-primary
xref: UnificationXref mint MINT-2202975
xref: RelationshipXref intact EBI-7525700 identity
evidence: Evidence a24dabfd-779a-4f00-bfba-c8c533b0f333 IM-15332-12484 432105 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:z-score: 1.00624892232031
comment: author-confidence:reliability score: 0.968
data source: intact
participant: rpab5_yeast
participant: Protein uniprotkb P04050 identity 1529029542456

UnificationXref mint MINT-2196798
type: UnificationXref
id: MINT-2196798
db: mint

rpa43_yeast
type: Protein
evidence: Evidence 22c93e65-6f6b-45ff-8699-e6e1716fc11a p 431568
entity reference: P46669
name: DNA-directed RNA polymerase I subunit RPA43
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-7203 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-7203
db: imex

RelationshipXref sgd S000001628
type: RelationshipXref
id: S000001628
db: sgd

RelationshipXref sgd S000000283
type: RelationshipXref
id: S000000283
db: sgd

RelationshipXref rcsb pdb 5DC3
type: RelationshipXref
id: 5DC3
db: protein data bank

ExperimentalForm d286b861-25ef-4b68-b5a3-7b664a4baaf2
type: ExperimentalForm
experimental feature: ModificationFeature 95789420-fbdc-4ec4-9960-7bdf34aed7af 430660
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 12624b3f-bf4a-4b34-a2c7-531db752122e
type: ExperimentalForm
experimental feature: ModificationFeature 5a68042d-4b88-45ff-9e6d-b5dd19afa9ef 432960
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

UnificationXref mint MINT-2208806
type: UnificationXref
id: MINT-2208806
db: mint

RelationshipXref intact EBI-7522804 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7522804
db: intact

Evidence 8f6d04dd-365d-4e81-9956-ccf11c038d25 IM-15332-4767 431001 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref mint MINT-2196780
type: UnificationXref
id: MINT-2196780
db: mint

Evidence bfa6b7f3-04d3-4c47-a886-3b0a5496c50f IM-15332-12494 432981 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm cc4f313e-ca52-416f-ab30-093e2601d308
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref mint MINT-2207456
type: UnificationXref
id: MINT-2207456
db: mint

RelationshipXref imex IM-15332-3994 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-3994
db: imex

RelationshipXref intact EBI-15702 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-15702
db: intact

rpa43_yeast
type: Protein
evidence: Evidence b2dc0eed-6068-4c8c-a47b-77fe29631fb6 p 431514
entity reference: P46669
name: DNA-directed RNA polymerase I subunit RPA43
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7530960 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7530960
db: intact

ExperimentalForm 57e067b8-77cb-45ed-bddb-4175c07e486f
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm b51a8bba-6be9-428c-8152-ceaf24674eb4
type: ExperimentalForm
experimental feature: ModificationFeature f6421f8c-9171-41ec-9691-b0b4411cba59 431724
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 6c8304af-4c31-47e2-9b29-95cc5f544540
type: ExperimentalForm
experimental feature: ModificationFeature 7a884be6-9f9f-4b79-81aa-d7527ca71574 431883
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7525362 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7525362
db: intact

RelationshipXref rcsb pdb 4OCN
type: RelationshipXref
id: 4OCN
db: protein data bank

RelationshipXref rcsb pdb 4OCM
type: RelationshipXref
id: 4OCM
db: protein data bank

UnificationXref mint MINT-2196762
type: UnificationXref
id: MINT-2196762
db: mint

rpn1-rpt5-3
type: MolecularInteraction
xref: RelationshipXref intact EBI-7541363 identity
xref: RelationshipXref imex IM-15332-10453 imex-primary
xref: UnificationXref mint MINT-2210012
evidence: Evidence 89a09171-5ffc-4c0e-bd09-c5f84f96c1e9 IM-15332-10453 433657 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 18.0432916206063
comment: author-confidence:reliability score: 0.984
comment: comment:mint
data source: intact
participant: Protein uniprotkb P38764 identity 1529029543232
participant: prs6a_yeast

UnificationXref mint MINT-2207438
type: UnificationXref
id: MINT-2207438
db: mint

RelationshipXref mint P50106
type: RelationshipXref
id: P50106
db: mint

RelationshipXref uniprotkb D6VRX1 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VRX1
db: uniprot knowledgebase

UnificationXref mint MINT-2206087
type: UnificationXref
id: MINT-2206087
db: mint

RelationshipXref intact EBI-17078 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-17078
db: intact

Evidence d74d9e2a-0b37-48ed-853e-9aeae3d7add5 IM-15332-3583 431493 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref go GO 0035307
type: RelationshipXref
id: GO:0035307
db: gene ontology

RelationshipXref interpro IPR007018
type: RelationshipXref
id: IPR007018
db: interpro

UnificationXref mint MINT-2207420
type: UnificationXref
id: MINT-2207420
db: mint

RelationshipXref go GO 0005938
type: RelationshipXref
id: GO:0005938
db: gene ontology

RelationshipXref intact EBI-23925 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-23925
db: intact

ExperimentalForm c376da9a-1bb9-4779-a1a1-1e79ac414108
type: ExperimentalForm
experimental feature: ModificationFeature 2a7e7a2f-dcd8-4d5c-8886-53c4f62dd862 430423
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 820c0567-cd64-450b-818f-1422897f7308
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref imex IM-15332-5986 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5986
db: imex

UnificationXref mint MINT-2196744
type: UnificationXref
id: MINT-2196744
db: mint

ExperimentalForm 248be032-3f58-4fbe-a287-77711b45d741
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

Evidence c4d6c01e-80bf-4dda-a32c-705c73c2d7ab IM-15332-10841 430409 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpl12a-rps24a
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-2366 imex-primary
xref: RelationshipXref intact EBI-7540277 identity
xref: UnificationXref mint MINT-2209598
evidence: Evidence eb881e5a-76b0-49f2-b921-62aebdf32d5c IM-15332-2366 433565 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.593
comment: author-confidence:z-score: 1.92849650007393
comment: comment:mint
data source: intact
participant: rl12_yeast
participant: Protein uniprotkb P26782 identity 1529029543186

UnificationXref uniprot knowledgebase Q03010
type: UnificationXref
id: Q03010
db: uniprot knowledgebase

UnificationXref mint MINT-2195393
type: UnificationXref
id: MINT-2195393
db: mint

RelationshipXref imex IM-15332-7629 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-7629
db: imex

UnificationXref mint MINT-2206069
type: UnificationXref
id: MINT-2206069
db: mint

Evidence aaf2caa4-57f3-4b49-8547-b50762fcdec6 IM-15332-3587 432289 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref intact EBI-7520432 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7520432
db: intact

ExperimentalForm 05162355-b1b2-4213-8905-bc5655727af7
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7518091 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7518091
db: intact

UnificationXref mint MINT-2200778
type: UnificationXref
id: MINT-2200778
db: mint

pti1_yeast
type: Protein
evidence: Evidence 62ec21a5-13e8-415c-8427-fea6dce1db55 p 430434
entity reference: P39927
name: Protein PTI1
comment: psi-mi participant
data source: intact

Evidence 2f87ed91-573e-4870-aade-63e93d750e1c IM-15332-10865 433809 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpc19-rpo31-2
type: MolecularInteraction
xref: RelationshipXref intact EBI-7532836 identity
xref: RelationshipXref imex IM-15332-5181 imex-primary
xref: UnificationXref mint MINT-2205997
evidence: Evidence e03737eb-370a-4fd0-ae93-e5530505214e IM-15332-5181 432765 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.631
comment: comment:mint
comment: author-confidence:z-score: 2.73062242758226
data source: intact
participant: Protein uniprotkb P04051 identity 1529029542786
participant: Protein uniprotkb P28000 identity 1529029542787

Evidence f2be31f2-bad1-4ff0-8750-c463a292fa31 IM-15332-11243 431597 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpc31-rpc37
type: MolecularInteraction
xref: UnificationXref mint MINT-2206555
xref: RelationshipXref imex IM-15332-10448 imex-primary
xref: RelationshipXref intact EBI-7534240 identity
evidence: Evidence 9d456180-4573-4b7e-817f-f2979bcbe966 IM-15332-10448 432889 430156
interaction type: physical association
comment: author-confidence:z-score: 8.5538747685371
comment: comment:mint
comment: author-confidence:reliability score: 0.5
data source: intact
participant: Protein uniprotkb P36121 identity 1529029542848
participant: rpc7_yeast

UnificationXref mint MINT-2196726
type: UnificationXref
id: MINT-2196726
db: mint

ExperimentalForm 562b16e3-ecbc-4d62-b76d-4019d993e448
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref mint MINT-2206051
type: UnificationXref
id: MINT-2206051
db: mint

RelationshipXref go GO 0043968
type: RelationshipXref
id: GO:0043968
db: gene ontology

RelationshipXref go GO 0043967
type: RelationshipXref
id: GO:0043967
db: gene ontology

RelationshipXref imex IM-15332-12476 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12476
db: imex

Evidence a27d4a75-0545-42c4-a512-99e1ced1c026 IM-15332-5587 431541 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref intact EBI-7530721 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7530721
db: intact

RelationshipXref intact EBI-7543566 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7543566
db: intact

RelationshipXref imex IM-15332-1225 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1225
db: imex

RelationshipXref imex IM-15332-2368 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-2368
db: imex

RelationshipXref sgd S000003855
type: RelationshipXref
id: S000003855
db: sgd

RelationshipXref intact EBI-7540309 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7540309
db: intact

Evidence ccb464fc-6993-4f4f-891d-959631698fad IM-15332-2737 430977 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rir4_yeast
type: ProteinReference
sequence: MEAHNQFLKTFQKERHDMKEAEKDEILLMENSRRFVMFPIKYHEIWAAYKKVEASFWTAEEIELAKDTEDFQKLTDDQKTYIGNLLALSISSDNLVNKYLIENFSAQLQNPEGKSFYGFQIMMENIYSEVYSMMVDAFFKDPKNIPLFKEIANLPEVKHKAAFIERWISNDDSLYAERLVAFAAKEGIFQAGNYASMFWLTDKKIMPGLAMANRNICRDRGAYTDFSCLLFAHLRTKPNPKIIEKIITEAVEIEKEYYSNSLPVEKFGMDLKSIHTYIEFVADGLLQGFGNEKYYNAVNPFEFMEDVATAGKTTFFEKKVSDYQKASDMSKSATPSKEINFDDDF
xref: RelationshipXref go GO 0009263
xref: RelationshipXref go GO 0051188
xref: RelationshipXref go GO 0046982
xref: UnificationXref uniprot knowledgebase P49723
xref: RelationshipXref sgd S000003412
xref: RelationshipXref rcsb pdb 1ZZD
xref: RelationshipXref go GO 0006260
xref: RelationshipXref uniprotkb Q66R92 secondary-ac
xref: RelationshipXref dip DIP-5381N
xref: RelationshipXref mint P49723
xref: RelationshipXref rcsb pdb 1JK0
xref: RelationshipXref interpro IPR000358
xref: RelationshipXref interpro IPR009078
xref: RelationshipXref interpro IPR030475
xref: RelationshipXref go GO 0004748
xref: RelationshipXref refseq NP 011696 3
xref: RelationshipXref rcsb pdb 1SMS
xref: RelationshipXref uniprotkb D6VUW4 secondary-ac
xref: RelationshipXref go GO 0005634
xref: RelationshipXref go GO 0005971
xref: RelationshipXref go GO 0005737
xref: RelationshipXref intact EBI-15251 identity
xref: RelationshipXref interpro IPR012348
xref: RelationshipXref interpro IPR033909
organism: http://identifiers.org/taxonomy/559292
name: Ribonucleotide reductase small subunit 2
name: Ribonucleotide reductase R2 subunit 2
name: YGR180C
name: RNR4
name: CRT3
name: Ribonucleoside-diphosphate reductase small chain 2

rpc40-rpa43-4
type: MolecularInteraction
xref: RelationshipXref intact EBI-7536169 identity
xref: RelationshipXref imex IM-15332-8029 imex-primary
xref: UnificationXref mint MINT-2207762
evidence: Evidence f7c15681-d012-492c-888c-406e5221965f IM-15332-8029 433157 430156
interaction type: physical association
comment: author-confidence:z-score: 0.0217392544715697
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P07703 identity 1529029542982
participant: rpa43_yeast

ExperimentalForm 34b0d3cf-6f5f-42e4-9c92-9a4b5b7049c2
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 959fa649-127c-4dff-9514-d3e1ebcf25f6
type: ExperimentalForm
experimental feature: ModificationFeature f74f7ec7-74eb-4f32-8f75-82e103a4f929 431291
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref go GO 0043951
type: RelationshipXref
id: GO:0043951
db: gene ontology

ExperimentalForm e0b34e08-0e45-4624-99a4-58c201c001d4
type: ExperimentalForm
experimental feature: ModificationFeature afaf611d-acb4-44c0-9b21-f92d0511072c 433212
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-8817 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-8817
db: imex

RelationshipXref imex IM-15332-8028 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-8028
db: imex

UnificationXref mint MINT-2195105
type: UnificationXref
id: MINT-2195105
db: mint

UnificationXref mint MINT-2196708
type: UnificationXref
id: MINT-2196708
db: mint

Evidence cc9e18ed-4051-44ab-bffe-fa4d0f1bc3a9 IM-15332-4765 430965 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref mint MINT-2206033
type: UnificationXref
id: MINT-2206033
db: mint

Evidence 40b66df9-8372-477e-bb04-d8ec35f2e27a IM-15332-2359 432465 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref interpro IPR007066
type: RelationshipXref
id: IPR007066
db: interpro

RelationshipXref imex IM-15332-401 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-401
db: imex

Evidence 1ea2c84d-4118-45ca-818a-cb5cda68565f IM-15332-2763 433873 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

eif3b_yeast
type: Protein
evidence: Evidence 69a8d3de-f324-41a0-bb8e-d0e5275bd73b p 433452
entity reference: P06103
name: Eukaryotic translation initiation factor 3 subunit B
comment: psi-mi participant
data source: intact

ExperimentalForm a43fdff0-3d26-4395-9db0-1b30aeda55ef
type: ExperimentalForm
experimental feature: ModificationFeature 478e6d20-5d57-42bf-b869-9388ba5a30f8 431487
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

UnificationXref mint MINT-2195357
type: UnificationXref
id: MINT-2195357
db: mint

reg1_yeast
type: Protein
evidence: Evidence 9bed50ff-7eb7-45cc-8e2a-ecfec953046d p 430478
entity reference: Q00816
name: Resistance to glucose repression protein 1
comment: psi-mi participant
data source: intact

ExperimentalForm 21b0077f-865c-4381-9dc7-5f6d747d8ff6
type: ExperimentalForm
experimental feature: ModificationFeature 2bd5a668-e938-48be-b2df-f0ec5acb9a98 430868
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-6383 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-6383
db: imex

rpa14-rpa43-2
type: MolecularInteraction
xref: UnificationXref mint MINT-2200562
xref: RelationshipXref imex IM-15332-3981 imex-primary
xref: RelationshipXref intact EBI-7522093 identity
evidence: Evidence c31bc100-c4c3-4c78-8494-6b3f88782ed7 IM-15332-3981 431569 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.989
comment: author-confidence:z-score: 9.00501704397029
comment: comment:mint
data source: intact
participant: Protein uniprotkb P46669 identity 1529029542189
participant: Protein uniprotkb P50106 identity 1529029542188

RelationshipXref imex IM-15332-1574 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1574
db: imex

eif3b_yeast
type: Protein
evidence: Evidence 919d48e3-a461-49fb-be7d-4ed0c4ee74bd p 433456
entity reference: P06103
name: Eukaryotic translation initiation factor 3 subunit B
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 1RYP
type: RelationshipXref
id: 1RYP
db: protein data bank

RelationshipXref rcsb pdb 4A3I
type: RelationshipXref
id: 4A3I
db: protein data bank

RelationshipXref intact EBI-8738 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-8738
db: intact

ExperimentalForm 88c193e9-a6cb-4a24-8df1-b564724a462b
type: ExperimentalForm
experimental feature: ModificationFeature b2a6c8ff-3900-4bd7-a9a9-e912fe3f0e27 430544
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref sgd S000003829
type: RelationshipXref
id: S000003829
db: sgd

RelationshipXref intact EBI-7518796 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7518796
db: intact

RelationshipXref rcsb pdb 4A3V
type: RelationshipXref
id: 4A3V
db: protein data bank

UnificationXref mint MINT-2206015
type: UnificationXref
id: MINT-2206015
db: mint

ExperimentalForm 5d47679c-bca9-4087-922f-82f848564529
type: ExperimentalForm
experimental feature: ModificationFeature 1f72d011-5ae2-4d71-b777-4dbaf9d5f789 433356
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref interpro IPR007081
type: RelationshipXref
id: IPR007081
db: interpro

RelationshipXref imex IM-15332-10850 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-10850
db: imex

Evidence 23d5bc8f-be3c-414f-8e34-881027e68dda IM-15332-1596 433469 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

eif3b_yeast
type: Protein
evidence: Evidence 3fed4889-635a-433b-b335-4b12f9d7efcb p 433482
entity reference: P06103
name: Eukaryotic translation initiation factor 3 subunit B
comment: psi-mi participant
data source: intact

rpn1-rpn8-6
type: MolecularInteraction
xref: RelationshipXref intact EBI-7543168 identity
xref: UnificationXref mint MINT-2210966
xref: RelationshipXref imex IM-15332-3601 imex-primary
evidence: Evidence 42dbdb02-64ce-4298-8170-46635e547de2 IM-15332-3601 433869 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.99
comment: author-confidence:z-score: 9.50544630035078
data source: intact
participant: Protein uniprotkb P38764 identity 1529029543338
participant: rpn8_yeast

rpd3-rco1
type: MolecularInteraction
xref: RelationshipXref intact EBI-7537543 identity
xref: RelationshipXref imex IM-15332-4405 imex-primary
xref: UnificationXref mint MINT-2208284
evidence: Evidence 861d0bb2-5a51-41a2-8d62-cd37aa51c6e0 IM-15332-4405 433273 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 6.53063354860286
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: rpd3_yeast
participant: Protein uniprotkb Q04779 identity 1529029543041

UnificationXref mint MINT-2195339
type: UnificationXref
id: MINT-2195339
db: mint

ExperimentalForm 00381249-a135-419f-8283-4bafabcfd99b
type: ExperimentalForm
experimental feature: ModificationFeature 6c27f9f1-7023-4d14-a895-85ddb0167a14 431875
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7517215 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7517215
db: intact

RelationshipXref dip DIP-4402N
type: RelationshipXref
id: DIP-4402N
db: database of interacting proteins

RelationshipXref imex IM-15332-411 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-411
db: imex

rpb9-rpb2-13
type: MolecularInteraction
xref: UnificationXref mint MINT-2205223
xref: RelationshipXref intact EBI-7531569 identity
xref: RelationshipXref imex IM-15332-11642 imex-primary
evidence: Evidence ab0e408d-803f-4e4b-bbe1-8a3ceba99832 IM-15332-11642 432593 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.989
comment: author-confidence:z-score: 2.43805855024023
comment: comment:mint
data source: intact
participant: Protein uniprotkb P08518 identity 1529029542700
participant: Protein uniprotkb P27999 identity 1529029542701

rpn1-rpt3-9
type: MolecularInteraction
xref: UnificationXref mint MINT-2210606
xref: RelationshipXref intact EBI-7542547 identity
xref: RelationshipXref imex IM-15332-3183 imex-primary
evidence: Evidence cead6e52-0376-465d-9f97-8f8f7c1db4dc IM-15332-3183 433789 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.989
comment: author-confidence:z-score: 5.98360613691767
comment: comment:mint
data source: intact
participant: Protein uniprotkb P33298 identity 1529029543299
participant: Protein uniprotkb P38764 identity 1529029543298

eif3b_yeast
type: Protein
evidence: Evidence b20a9004-ecb2-4c17-8319-94f930c2e817 p 433502
entity reference: P06103
name: Eukaryotic translation initiation factor 3 subunit B
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-11242 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-11242
db: imex

rco1-eaf3-8
type: MolecularInteraction
xref: UnificationXref mint MINT-2195321
xref: RelationshipXref imex IM-15332-5968 imex-primary
xref: RelationshipXref intact EBI-7515206 identity
evidence: Evidence d7081a7f-66c9-48ee-aad8-819d166c2d37 IM-15332-5968 430405 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.989
comment: comment:mint
comment: author-confidence:z-score: 0.0898891365541392
data source: intact
participant: eaf3_yeast
participant: rco1_yeast

UnificationXref mint MINT-2195141
type: UnificationXref
id: MINT-2195141
db: mint

UnificationXref mint MINT-2195321
type: UnificationXref
id: MINT-2195321
db: mint

RelationshipXref imex IM-15332-2762 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-2762
db: imex

RelationshipXref go GO 0042564
type: RelationshipXref
id: GO:0042564
db: gene ontology

UnificationXref mint MINT-2211038
type: UnificationXref
id: MINT-2211038
db: mint

UnificationXref uniprot knowledgebase P34087
type: UnificationXref
id: P34087
db: uniprot knowledgebase

Evidence e03737eb-370a-4fd0-ae93-e5530505214e IM-15332-5181 432765 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref go GO 0000446
type: RelationshipXref
id: GO:0000446
db: gene ontology

RelationshipXref imex IM-15332-3601 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-3601
db: imex

rpb8-yp225-2
type: MolecularInteraction
xref: RelationshipXref intact EBI-7528381 identity
xref: RelationshipXref imex IM-15332-4396 imex-primary
xref: UnificationXref mint MINT-2204039
evidence: Evidence 1c928dc0-8f16-413c-bf64-0eb9be0edbd6 IM-15332-4396 432341 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.989
comment: author-confidence:z-score: 9.56682297945613
comment: comment:mint
data source: intact
participant: Protein uniprotkb Q08971 identity 1529029542574
participant: rpab3_yeast

ExperimentalForm e0940691-d353-436a-8859-cb60798941d3
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref imex IM-15332-4405 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-4405
db: imex

RelationshipXref imex IM-15332-5978 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5978
db: imex

ExperimentalForm c6b762d0-bf5d-45c2-94e9-83a3019bc27f
type: ExperimentalForm
experimental feature: ModificationFeature 2e6ac78b-6393-412a-88e5-7ae52ed6dc9d 433071
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm f43c0bc5-efd0-4589-ae2a-e1927f66e276
type: ExperimentalForm
experimental feature: ModificationFeature 3e131160-3fe4-4499-b662-1d4ca1cf9bf6 432432
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ima1_yeast
type: ProteinReference
sequence: MDNGTDSSTSKFVPEYRRTNFKNKGRFSADELRRRRDTQQVELRKAKRDEALAKRRNFIPPTDGADSDEEDESSVSADQQFYSQLQQELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIEVTLDALENILKMGEADKEARGLNINENADFIEKAGGMEKIFNCQQNENDKIYEKAYKIIETYFGEEEDAVDETMAPQNAGNTFGFGSNVNQQFNFN
xref: RelationshipXref rcsb pdb 1UN0
xref: RelationshipXref go GO 0031144
xref: RelationshipXref rcsb pdb 5T94
xref: RelationshipXref rcsb pdb 2C1T
xref: RelationshipXref rcsb pdb 1BK6
xref: RelationshipXref rcsb pdb 1BK5
xref: RelationshipXref rcsb pdb 4PVZ
xref: RelationshipXref intact EBI-1797 identity
xref: RelationshipXref sgd S000005133
xref: RelationshipXref uniprotkb D6W0Z8 secondary-ac
xref: RelationshipXref go GO 0032991
xref: RelationshipXref rcsb pdb 1WA5
xref: RelationshipXref go GO 0005829
xref: RelationshipXref dip DIP-728N
xref: RelationshipXref interpro IPR011989
xref: RelationshipXref rcsb pdb 1EE5
xref: RelationshipXref rcsb pdb 1EE4
xref: RelationshipXref interpro IPR032413
xref: RelationshipXref go GO 0006612
xref: RelationshipXref interpro IPR036975
xref: RelationshipXref go GO 0008565
xref: RelationshipXref go GO 0061608
xref: RelationshipXref go GO 0005643
xref: RelationshipXref go GO 0005634
xref: RelationshipXref interpro IPR000225
xref: UnificationXref uniprot knowledgebase Q02821
xref: RelationshipXref go GO 0006607
xref: RelationshipXref go GO 0006606
xref: RelationshipXref go GO 0048471
xref: RelationshipXref rcsb pdb 4XZR
xref: RelationshipXref go GO 0097718
xref: RelationshipXref go GO 0005737
xref: RelationshipXref interpro IPR002652
xref: RelationshipXref interpro IPR024931
xref: RelationshipXref go GO 0042564
xref: RelationshipXref rcsb pdb 5H2X
xref: RelationshipXref interpro IPR016024
xref: RelationshipXref refseq NP 014210 1
xref: RelationshipXref rcsb pdb 5H2W
xref: RelationshipXref go GO 0008139
xref: RelationshipXref mint Q02821
xref: RelationshipXref go GO 0005654
organism: http://identifiers.org/taxonomy/559292
name: KAP60
name: Importin subunit alpha
name: N1606
name: SRP1
name: YNL189W
name: Karyopherin subunit alpha
name: Karyopherin-60
name: Serine-rich RNA polymerase I suppressor protein

RelationshipXref intact EBI-7515395 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7515395
db: intact

ExperimentalForm 050b0c4e-3919-4476-a669-d13befb9966b
type: ExperimentalForm
experimental feature: ModificationFeature 802d2aae-b2b5-4793-9c47-513e32c536ef 433852
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpc34-rpc40
type: MolecularInteraction
xref: RelationshipXref intact EBI-7534528 identity
xref: UnificationXref mint MINT-2206772
xref: RelationshipXref imex IM-15332-11645 imex-primary
evidence: Evidence 44a9c153-12f8-4515-8fa8-fe5e167261aa IM-15332-11645 432937 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.925
comment: author-confidence:z-score: 9.40243917845636
comment: comment:mint
data source: intact
participant: Protein uniprotkb P32910 identity 1529029542873
participant: Protein uniprotkb P07703 identity 1529029542872

rpc19-rpa135-2
type: MolecularInteraction
xref: UnificationXref mint MINT-2205907
xref: RelationshipXref intact EBI-7532717 identity
xref: RelationshipXref imex IM-15332-1960 imex-primary
evidence: Evidence 66e8df6c-e9b9-43aa-9114-265df82a0cf7 IM-15332-1960 432745 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.875
comment: author-confidence:z-score: 1.53403294175793
comment: comment:mint
data source: intact
participant: Protein uniprotkb P28000 identity 1529029542777
participant: rpa2_yeast

rpb10-rpb3
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-8417 imex-primary
xref: RelationshipXref intact EBI-7524368 identity
xref: UnificationXref mint MINT-2202183
evidence: Evidence 57f173bf-9448-4f98-b013-a95cf215225b IM-15332-8417 431929 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 0.57020691050525
comment: comment:mint
comment: author-confidence:reliability score: 0.944
data source: intact
participant: Protein uniprotkb P16370 identity 1529029542368
participant: rpab5_yeast

ExperimentalForm a65aece7-3bfb-4bc9-a799-d388954428ff
type: ExperimentalForm
experimental feature: ModificationFeature 597359d7-7ba4-4b67-ae74-742fc25d8b17 431063
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

Evidence ecdbea27-8a1a-4438-b616-337dfc54f921 IM-15332-4389 431553 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref sgd S000001094
type: RelationshipXref
id: S000001094
db: sgd

ExperimentalForm 2afa710f-5e32-40ee-b9ca-33afa1d3cfdb
type: ExperimentalForm
experimental feature: ModificationFeature dae99b06-69fd-4f79-b500-90f7aa9bf277 431183
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-11252 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-11252
db: imex

RelationshipXref interpro IPR004365
type: RelationshipXref
id: IPR004365
db: interpro

rpc40-rpc37
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-1592 imex-primary
xref: RelationshipXref intact EBI-7535520 identity
xref: UnificationXref mint MINT-2207294
evidence: Evidence 3154b7f2-ef39-41df-938a-4670f7b7b775 IM-15332-1592 433053 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.983
comment: author-confidence:z-score: 7.65742122930919
comment: comment:mint
data source: intact
participant: Protein uniprotkb P36121 identity 1529029542930
participant: Protein uniprotkb P07703 identity 1529029542931

RelationshipXref sgd S000002435
type: RelationshipXref
id: S000002435
db: sgd

UnificationXref mint MINT-2196510
type: UnificationXref
id: MINT-2196510
db: mint

RelationshipXref uniprotkb D6VSC1 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VSC1
db: uniprot knowledgebase

RelationshipXref imex IM-15332-12056 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12056
db: imex

ExperimentalForm ba0c77a8-48c4-4cc6-8655-37042d03f031
type: ExperimentalForm
experimental feature: ModificationFeature 029869ca-53f6-4643-8e9c-af5992972cb3 431096
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref go GO 0000451
type: RelationshipXref
id: GO:0000451
db: gene ontology

RelationshipXref uniprotkb D3DLU1 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D3DLU1
db: uniprot knowledgebase

RelationshipXref interpro IPR008476
type: RelationshipXref
id: IPR008476
db: interpro

Evidence 7547d6b6-60e0-4d5b-a67c-d0b95e4058bc IM-15332-2350 431425 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref refseq NP 009958 2
type: RelationshipXref
id: NP_009958.2
db: refseq

ExperimentalForm e60c121c-0858-4ac3-8fdd-c69f4d5029b2
type: ExperimentalForm
experimental feature: ModificationFeature e1f3c15b-8698-4fb2-bf16-7c7ea7bb784b 430488
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 50e6a1f4-5950-4f7f-ac36-4116c539d272
type: ExperimentalForm
experimental feature: ModificationFeature c7dba0ac-86d9-4f23-b1a5-942a785bda89 430887
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref mint P38741
type: RelationshipXref
id: P38741
db: mint

ExperimentalForm e68780fa-4a80-4864-bdb9-7dfd6eafb243
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm b1346d59-ce8f-484a-849b-b0ddf092af95
type: ExperimentalForm
experimental feature: ModificationFeature 0b79d618-418f-49cf-aec3-4473851113e2 432988
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref go GO 0033186
type: RelationshipXref
id: GO:0033186
db: gene ontology

RelationshipXref intact EBI-7519053 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7519053
db: intact

rpb9-tfg1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-2359 imex-primary
xref: UnificationXref mint MINT-2204618
xref: RelationshipXref intact EBI-7530721 identity
evidence: Evidence 40b66df9-8372-477e-bb04-d8ec35f2e27a IM-15332-2359 432465 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.887
comment: author-confidence:z-score: -0.0353270893673085
comment: comment:mint
data source: intact
participant: Protein uniprotkb P41895 identity 1529029542637
participant: Protein uniprotkb P27999 identity 1529029542636

ExperimentalForm abb96d30-4a31-449d-9c8b-a35ae7770a1d
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-5832 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-5832
db: intact

ExperimentalForm 22cc1819-3fdd-4022-8ceb-769be7633ed0
type: ExperimentalForm
experimental feature: ModificationFeature b21ef509-4078-4438-9ee4-62b788ce31ff 433575
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm a00e65f0-029e-4a43-b64e-e780e5887c29
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref sgd S000001069
type: RelationshipXref
id: S000001069
db: sgd

ExperimentalForm 03a3169c-f9d3-40db-b08c-9d210cb4a272
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpb9-rpb5
type: MolecularInteraction
xref: UnificationXref mint MINT-2204909
xref: RelationshipXref imex IM-15332-401 imex-primary
xref: RelationshipXref intact EBI-7531222 identity
evidence: Evidence 36ce7379-5a58-4ae4-81b3-d3ee08bfcdb1 IM-15332-401 432529 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.968
comment: author-confidence:z-score: 4.66398345912721
data source: intact
participant: rpab1_yeast
participant: Protein uniprotkb P27999 identity 1529029542669

Evidence c4731f13-4a33-412d-8304-838f7fe6d8ca IM-15332-12493 432849 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref refseq NP 014260 3
type: RelationshipXref
id: NP_014260.3
db: refseq

RelationshipXref intact EBI-7516242 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7516242
db: intact

ExperimentalForm f93300fa-d872-4ed8-8a9d-507ab4297de3
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref refseq NP 014760 3
type: RelationshipXref
id: NP_014760.3
db: refseq

RelationshipXref imex IM-15332-11631 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-11631
db: imex

ExperimentalForm 86049c2b-f653-433c-8c3a-35d53ac2eb08
type: ExperimentalForm
experimental feature: ModificationFeature c4c5e0d7-8423-4026-8982-e2ddf30c3071 433836
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7537205 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7537205
db: intact

RelationshipXref dip DIP-698N
type: RelationshipXref
id: DIP-698N
db: database of interacting proteins

ExperimentalForm e14ed208-0ccc-4e91-a1a3-74ebcfa88e66
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

Evidence 1663b22b-7f43-4130-8d44-d5f03ca55cc6 IM-15332-8823 433553 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

Evidence c4de2534-524d-4f41-96da-892f5d81a96e IM-15332-4410 433705 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm 26a68505-4713-4552-bdb4-86ebe48124e7
type: ExperimentalForm
experimental feature: ModificationFeature babac328-cfbc-4458-ac69-fc0bcefcb646 432080
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7541717 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7541717
db: intact

RelationshipXref mint P39708
type: RelationshipXref
id: P39708
db: mint

RelationshipXref rcsb pdb 3K8T
type: RelationshipXref
id: 3K8T
db: protein data bank

RelationshipXref uniprotkb D6VZB1 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VZB1
db: uniprot knowledgebase

rpn1-yen1-1
type: MolecularInteraction
xref: RelationshipXref intact EBI-7543405 identity
xref: RelationshipXref imex IM-15332-6390 imex-primary
xref: UnificationXref mint MINT-2211020
evidence: Evidence fdae92f4-3d0d-4814-a0df-d5347b43a2a7 IM-15332-6390 433881 430156
interaction type: physical association
comment: comment:mint
comment: author-confidence:z-score: 3.69213492878297
comment: author-confidence:reliability score: 0.676
data source: intact
participant: Protein uniprotkb P40028 identity 1529029543344
participant: Protein uniprotkb P38764 identity 1529029543345

ExperimentalForm 1f14d317-8e20-409a-b34b-43fdb994a1cf
type: ExperimentalForm
experimental feature: ModificationFeature bd87de6b-9c23-49fc-9fe1-c5ecf7512289 430675
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref mint P22147
type: RelationshipXref
id: P22147
db: mint

Evidence 5ec4b1f4-a83f-4cb4-afaa-fd084d332552 IM-15332-5189 433761 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm 0a7e48c3-1a84-436f-818d-8bd4df90d55c
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref interpro IPR033658
type: RelationshipXref
id: IPR033658
db: interpro

RelationshipXref mint P38782
type: RelationshipXref
id: P38782
db: mint

RelationshipXref rcsb pdb 3K7A
type: RelationshipXref
id: 3K7A
db: protein data bank

RelationshipXref imex IM-15332-8432 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-8432
db: imex

UnificationXref mint MINT-2209778
type: UnificationXref
id: MINT-2209778
db: mint

RelationshipXref mint P22138
type: RelationshipXref
id: P22138
db: mint

RelationshipXref interpro IPR012993
type: RelationshipXref
id: IPR012993
db: interpro

RelationshipXref go GO 0070481
type: RelationshipXref
id: GO:0070481
db: gene ontology

rpab1_yeast
type: Protein
evidence: Evidence 2cb2b1a6-b76d-4876-a001-b39adb063d8e p 432086
entity reference: rpab1_yeast
name: DNA-directed RNA polymerases I, II, and III subunit RPABC1
comment: psi-mi participant
data source: intact

rpc19-rpc25
type: MolecularInteraction
xref: RelationshipXref intact EBI-7533045 identity
xref: RelationshipXref imex IM-15332-1590 imex-primary
xref: UnificationXref mint MINT-2206177
evidence: Evidence d3d366a0-6310-4fe7-ad11-f5ca3c58cfdb IM-15332-1590 432805 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.964
comment: comment:homomint
comment: comment:mint
comment: author-confidence:z-score: 2.11693696682715
data source: intact
participant: rpc8_yeast
participant: rpac2_yeast

ExperimentalForm 2f24b9dd-95d6-453f-9aab-17a311f129c1
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7526885 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7526885
db: intact

RelationshipXref mint Q12159
type: RelationshipXref
id: Q12159
db: mint

UnificationXref uniprot knowledgebase P27999
type: UnificationXref
id: P27999
db: uniprot knowledgebase

RelationshipXref dip DIP-5261N
type: RelationshipXref
id: DIP-5261N
db: database of interacting proteins

rpc34-ret1-1
type: MolecularInteraction
xref: UnificationXref mint MINT-2206952
xref: RelationshipXref intact EBI-7534747 identity
xref: RelationshipXref imex IM-15332-6384 imex-primary
evidence: Evidence 07802086-21eb-4773-b788-fed9251c83f5 IM-15332-6384 432977 430156
interaction type: physical association
comment: author-confidence:z-score: 2.68207970251309
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: rpc6_yeast
participant: Protein uniprotkb P22276 identity 1529029542893

RelationshipXref imex IM-15332-3159 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-3159
db: imex

RelationshipXref intact EBI-7533371 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7533371
db: intact

UnificationXref mint MINT-2196582
type: UnificationXref
id: MINT-2196582
db: mint

Evidence 69fafd99-c0ad-456e-aa62-4a3a62c12c25 IM-15332-6368 431149 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpl43a-cbr1
type: MolecularInteraction
xref: RelationshipXref intact EBI-7540872 identity
xref: UnificationXref mint MINT-2209850
xref: RelationshipXref imex IM-15332-9622 imex-primary
evidence: Evidence 650a64ac-3722-40cd-b1c2-be62e6b45505 IM-15332-9622 433621 430156
interaction type: physical association
comment: author-confidence:z-score: 0.33203914127634
comment: author-confidence:reliability score: 0.813
comment: comment:mint
data source: intact
participant: rl43_yeast
participant: Protein uniprotkb P38626 identity 1529029543214

RelationshipXref rcsb pdb 4NO9
type: RelationshipXref
id: 4NO9
db: protein data bank

RelationshipXref rcsb pdb 4NO8
type: RelationshipXref
id: 4NO8
db: protein data bank

ExperimentalForm 42523634-0238-42a3-8f5b-04676dc2f20d
type: ExperimentalForm
experimental feature: ModificationFeature 0aa6d827-c654-416c-8c8b-566a23c9a982 431623
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpb9-rpb2-2
type: MolecularInteraction
xref: UnificationXref mint MINT-2204442
xref: RelationshipXref imex IM-15332-8421 imex-primary
xref: RelationshipXref intact EBI-7530123 identity
evidence: Evidence c4166a96-2440-43db-b566-1a354aa084fc IM-15332-8421 432429 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.989
comment: author-confidence:z-score: 0.456842517994658
comment: comment:mint
data source: intact
participant: Protein uniprotkb P08518 identity 1529029542618
participant: Protein uniprotkb P27999 identity 1529029542619

ExperimentalForm ee1004fb-d9de-4602-8bef-f5a4cac872c5
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7531207 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7531207
db: intact

RelationshipXref intact EBI-7533097 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7533097
db: intact

rpc40-rpo26-1
type: MolecularInteraction
xref: UnificationXref mint MINT-2207060
xref: RelationshipXref intact EBI-7534882 identity
xref: RelationshipXref imex IM-15332-2758 imex-primary
evidence: Evidence ee6b900c-95be-4e98-85de-612bd29add3b IM-15332-2758 433001 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.989
comment: author-confidence:z-score: -0.15788511838599
comment: comment:mint
data source: intact
participant: Protein uniprotkb P20435 identity 1529029542904
participant: Protein uniprotkb P07703 identity 1529029542905

UnificationXref mint MINT-2209796
type: UnificationXref
id: MINT-2209796
db: mint

ExperimentalForm 196fd17a-e419-40d1-b6c8-95009fa50acd
type: ExperimentalForm
experimental feature: ModificationFeature d630dfdf-928d-4c75-85db-e9925108a13d 432740
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

prs6a_yeast
type: Protein
evidence: Evidence 4c1efea3-8f7d-4ccc-9d98-7b40cc7da78b p 433894
entity reference: P33297
name: 26S proteasome regulatory subunit 6A
comment: psi-mi participant
data source: intact

RelationshipXref reactome R-SCE-70171
type: RelationshipXref
id: R-SCE-70171
db: reactome

Evidence 56eb2da3-ef13-4eac-8b8b-07def267adcc IM-15332-6370 431249 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref mint MINT-2208788
type: UnificationXref
id: MINT-2208788
db: mint

RelationshipXref intact EBI-7536426 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7536426
db: intact

ExperimentalForm bc335580-50be-44bd-bd39-8712cea25f9c
type: ExperimentalForm
experimental feature: ModificationFeature 4ee3efeb-84e1-4d41-bb4a-2bbda324636b 432471
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpb9-rpb2-1
type: MolecularInteraction
xref: UnificationXref mint MINT-2204406
xref: RelationshipXref imex IM-15332-3988 imex-primary
xref: RelationshipXref intact EBI-7530041 identity
evidence: Evidence 3f17e4ce-685a-4828-a177-36a085c49036 IM-15332-3988 432421 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.989
comment: author-confidence:z-score: 0.516870904653495
comment: comment:mint
data source: intact
participant: Protein uniprotkb P27999 identity 1529029542614
participant: Protein uniprotkb P08518 identity 1529029542615

RelationshipXref dip DIP-6745N
type: RelationshipXref
id: DIP-6745N
db: database of interacting proteins

ExperimentalForm 7e8b6179-93bf-4ba8-aa9b-fb5539084862
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref uniprotkb D6W132 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6W132
db: uniprot knowledgebase

Evidence ef88ca81-ff91-4b52-a35a-b882980c35cc IM-15332-10034 432897 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref mint MINT-2208770
type: UnificationXref
id: MINT-2208770
db: mint

RelationshipXref intact EBI-7529812 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7529812
db: intact

RelationshipXref mint P38304
type: RelationshipXref
id: P38304
db: mint

RelationshipXref mint P46995
type: RelationshipXref
id: P46995
db: mint

RelationshipXref sgd S000000322
type: RelationshipXref
id: S000000322
db: sgd

ExperimentalForm df2d226c-52f1-49ea-ac31-cb270d36969b
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ipyr_yeast
type: Protein
evidence: Evidence 28ac2aba-aa89-45b3-8c35-07a51d59f022 p 431482
entity reference: P00817
name: Inorganic pyrophosphatase
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7543084 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7543084
db: intact

rpa1_yeast
type: Protein
evidence: Evidence ccca8a62-cd41-4570-bbb2-ef1a12821ca7 p 431848
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

rnr1-rnr3-13
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-3165 imex-primary
xref: UnificationXref mint MINT-2199860
xref: RelationshipXref intact EBI-7520930 identity
evidence: Evidence 81dc7e4e-3b44-45f6-861c-6791b22aa635 IM-15332-3165 431413 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.906
comment: comment:homomint
comment: author-confidence:z-score: 2.193869465744
comment: comment:mint
data source: intact
participant: rir3_yeast
participant: Protein uniprotkb P21524 identity 1529029542110

rpa135-rpc40
type: MolecularInteraction
xref: RelationshipXref intact EBI-7522011 identity
xref: UnificationXref mint MINT-2200490
xref: RelationshipXref imex IM-15332-4389 imex-primary
evidence: Evidence ecdbea27-8a1a-4438-b616-337dfc54f921 IM-15332-4389 431553 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 9.1611710638779
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P22138 identity 1529029542181
participant: Protein uniprotkb P07703 identity 1529029542180

RelationshipXref mint P50095
type: RelationshipXref
id: P50095
db: mint

RelationshipXref imex IM-15332-3181 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-3181
db: imex

Evidence 765eef45-b1a7-433b-98d6-3c1668057f0e IM-15332-7637 432197 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref interpro IPR012948
type: RelationshipXref
id: IPR012948
db: interpro

ExperimentalForm 8bfb682c-950a-47a9-be84-2e5b8f200692
type: ExperimentalForm
experimental feature: ModificationFeature bf65217f-9a96-48b1-800e-a9f06a54d625 433115
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 8f63b6b3-588c-4709-b181-055d76d48a55
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref mint MINT-2208752
type: UnificationXref
id: MINT-2208752
db: mint

RelationshipXref rcsb pdb 3K1F
type: RelationshipXref
id: 3K1F
db: protein data bank

RelationshipXref mint Q12102
type: RelationshipXref
id: Q12102
db: mint

RelationshipXref uniprotkb D3DLS0 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D3DLS0
db: uniprot knowledgebase

RelationshipXref rcsb pdb 1Y14
type: RelationshipXref
id: 1Y14
db: protein data bank

RelationshipXref mint P17629
type: RelationshipXref
id: P17629
db: mint

RelationshipXref rcsb pdb 2FUL
type: RelationshipXref
id: 2FUL
db: protein data bank

RelationshipXref imex IM-15332-10042 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-10042
db: imex

t2fb_yeast
type: Protein
evidence: Evidence a58970b3-d462-4dbf-8aed-fbe407eef011 p 432150
entity reference: P41896
name: Transcription initiation factor IIF subunit beta
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7535949 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7535949
db: intact

ExperimentalForm 5592bfab-4550-4369-9dcf-9858cb360fcb
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 880c7b2b-5808-4bab-a653-6ab05565009c
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref sgd S000000358
type: RelationshipXref
id: S000000358
db: sgd

t2fb_yeast
type: Protein
evidence: Evidence 17b0849f-8596-4e22-8b3e-9c0ed5c33b79 p 432128
entity reference: P41896
name: Transcription initiation factor IIF subunit beta
comment: psi-mi participant
data source: intact

Evidence badcb39c-67f1-4b96-904a-0c482ee138a2 IM-15332-10033 432857 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref mint MINT-2208734
type: UnificationXref
id: MINT-2208734
db: mint

t2fb_yeast
type: Protein
evidence: Evidence 3a0734ed-dd40-4e75-aee4-7be6803572c5 p 432116
entity reference: P41896
name: Transcription initiation factor IIF subunit beta
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7525258 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7525258
db: intact

RelationshipXref imex IM-15332-5173 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5173
db: imex

RelationshipXref go GO 0035267
type: RelationshipXref
id: GO:0035267
db: gene ontology

RelationshipXref mint P51401
type: RelationshipXref
id: P51401
db: mint

RelationshipXref intact EBI-7542660 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7542660
db: intact

RelationshipXref intact EBI-7532836 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7532836
db: intact

RelationshipXref intact EBI-8965 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-8965
db: intact

rpc17-rpb5-1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-1588 imex-primary
xref: UnificationXref mint MINT-2205583
xref: RelationshipXref intact EBI-7532159 identity
evidence: Evidence 4b2cb519-2477-4b32-9aa8-cad334fd873a IM-15332-1588 432673 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.982
comment: author-confidence:z-score: 9.27899997411307
comment: comment:mint
data source: intact
participant: rpab1_yeast
participant: rpc9_yeast

RelationshipXref rcsb pdb 2FSB
type: RelationshipXref
id: 2FSB
db: protein data bank

RelationshipXref imex IM-15332-1956 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1956
db: imex

RelationshipXref refseq NP 011925 1
type: RelationshipXref
id: NP_011925.1
db: refseq

rl43_yeast
type: Protein
evidence: Evidence dd79914e-266c-4d34-8cfa-1c963d260a36 p 433623
entity reference: P49631
name: 60S ribosomal protein L43
comment: psi-mi participant
data source: intact

RelationshipXref uniprotkb D6W4A9 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6W4A9
db: uniprot knowledgebase

rfa3-rfa1-5
type: MolecularInteraction
xref: RelationshipXref intact EBI-7517452 identity
xref: RelationshipXref imex IM-15332-2736 imex-primary
xref: UnificationXref mint MINT-2197357
evidence: Evidence 8f789f15-49b6-49bc-b602-7819b2745a69 IM-15332-2736 430857 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.988
comment: author-confidence:z-score: 6.41074690052733
comment: comment:mint
data source: intact
participant: rfa3_yeast
participant: Protein uniprotkb P22336 identity 1529029541833

Evidence d8ce7922-0614-470b-9d58-0d9857d78374 IM-15332-10859 433165 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref intact EBI-7516118 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7516118
db: intact

UnificationXref mint MINT-2208716
type: UnificationXref
id: MINT-2208716
db: mint

Evidence c383e689-e97d-4154-b599-601efbfea383 IM-15332-9196 431049 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm f74fe316-ea1f-4b46-b02a-77ea66d16ba1
type: ExperimentalForm
experimental feature: ModificationFeature 9ef8e73c-1642-48ae-9017-26a82793307c 431036
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm a2efb357-f046-4f3b-b194-31cfe121a4f4
type: ExperimentalForm
experimental feature: ModificationFeature 1b40627b-c882-4169-a5ae-918e7b609a69 430555
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

UnificationXref mint MINT-2196690
type: UnificationXref
id: MINT-2196690
db: mint

ExperimentalForm 2f522bd9-887a-4d99-a818-eaa80ae4f4f1
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref mint MINT-2207366
type: UnificationXref
id: MINT-2207366
db: mint

RelationshipXref interpro IPR011545
type: RelationshipXref
id: IPR011545
db: interpro

rpb11-spt5
type: MolecularInteraction
xref: UnificationXref mint MINT-2203209
xref: RelationshipXref intact EBI-7526369 identity
xref: RelationshipXref imex IM-15332-10440 imex-primary
evidence: Evidence 711440b8-93ee-4131-9918-a96b2b9793bc IM-15332-10440 432157 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 2.76612997010378
comment: author-confidence:reliability score: 0.555
comment: comment:mint
data source: intact
participant: Protein uniprotkb P38902 identity 1529029542482
participant: Protein uniprotkb P27692 identity 1529029542483

RelationshipXref imex IM-15332-10446 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-10446
db: imex

ExperimentalForm 664f12fe-48fb-45dc-b618-2c6c7e581987
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref dip DIP-4537N
type: RelationshipXref
id: DIP-4537N
db: database of interacting proteins

Evidence 3154b7f2-ef39-41df-938a-4670f7b7b775 IM-15332-1592 433053 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref refseq NP 014332 1
type: RelationshipXref
id: NP_014332.1
db: refseq

RelationshipXref go GO 0015918
type: RelationshipXref
id: GO:0015918
db: gene ontology

RelationshipXref intact EBI-7542468 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7542468
db: intact

ExperimentalForm 50b4b665-71ab-4ab0-803f-ce4273485f9f
type: ExperimentalForm
experimental feature: ModificationFeature c27600a3-91b6-4a3f-8570-1fe8f8e7f633 431415
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7532079 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7532079
db: intact

UnificationXref mint MINT-2196672
type: UnificationXref
id: MINT-2196672
db: mint

rpn2_yeast
type: Protein
evidence: Evidence e855b796-91f0-4cf3-afbb-ae759e8a8d29 p 433856
entity reference: P32565
name: 26S proteasome regulatory subunit RPN2
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2207348
type: UnificationXref
id: MINT-2207348
db: mint

Evidence 0c0ecfcc-a3b8-42c0-b4ab-b25fcd5c828c IM-15332-8429 433309 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rnr4-rnr2-3
type: MolecularInteraction
xref: UnificationXref mint MINT-2200040
xref: RelationshipXref imex IM-15332-4770 imex-primary
xref: RelationshipXref intact EBI-7521187 identity
evidence: Evidence a06cdf7a-40c4-445a-a8aa-1f32a41cfbc6 IM-15332-4770 431453 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.877
comment: comment:mint
comment: author-confidence:z-score: 3.61942098746306
data source: intact
participant: Protein uniprotkb P49723 identity 1529029542131
participant: Protein uniprotkb P09938 identity 1529029542130

UnificationXref mint MINT-2207006
type: UnificationXref
id: MINT-2207006
db: mint

rfa2-dna2-3
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-11631 imex-primary
xref: UnificationXref mint MINT-2197032
xref: RelationshipXref intact EBI-7517122 identity
evidence: Evidence 11ce63cf-ae2c-4220-a9c3-68d02428df1f IM-15332-11631 430785 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.771
comment: comment:mint
comment: author-confidence:z-score: 0.411951918854663
data source: intact
participant: dna2_yeast
participant: rfa2_yeast

RelationshipXref imex IM-15332-3991 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-3991
db: imex

RelationshipXref dip DIP-4313N
type: RelationshipXref
id: DIP-4313N
db: database of interacting proteins

RelationshipXref imex IM-15332-4795 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-4795
db: imex

rpab3_yeast
type: Protein
evidence: Evidence 351eb62f-bfb8-473e-a68d-6d33ccec1b21 p 432407
entity reference: P20436
name: DNA-directed RNA polymerases I, II, and III subunit RPABC3
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2207330
type: UnificationXref
id: MINT-2207330
db: mint

rpab3_yeast
type: Protein
evidence: Evidence 17dfe1c8-c941-4e15-bd4d-396d59b87d5b p 432395
entity reference: P20436
name: DNA-directed RNA polymerases I, II, and III subunit RPABC3
comment: psi-mi participant
data source: intact

ExperimentalForm 7d6257f9-b2fc-4c6c-83ca-1663a0639cce
type: ExperimentalForm
experimental feature: ModificationFeature bb6e854e-bb93-4b98-a17b-d81c1f249bbe 433164
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref dip DIP-2469N
type: RelationshipXref
id: DIP-2469N
db: database of interacting proteins

Evidence eb86f7fa-e4f9-43a4-9496-5c10b6c00214 IM-15332-9217 433853 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref imex IM-15332-5599 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5599
db: imex

ExperimentalForm 0f3592e9-b87c-45cc-b903-d8b95d3fcfc0
type: ExperimentalForm
experimental feature: ModificationFeature ab03a421-dfaa-4e03-bbb7-13cf32ee19a6 433108
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

Evidence 8cadd558-f600-476b-9035-6f143d5cbdf7 IM-15332-3154 430485 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

Evidence 79213e97-bdc1-425f-af79-502df6e5bb18 IM-15332-2756 432873 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref imex IM-15332-11634 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-11634
db: imex

rpb11-tfg1-1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-8813 imex-primary
xref: UnificationXref mint MINT-2203119
xref: RelationshipXref intact EBI-7526103 identity
evidence: Evidence ad34cdcd-b14e-4e6b-9a9b-da6e4e0c49a7 IM-15332-8813 432137 430156
interaction type: physical association
comment: author-confidence:z-score: 1.08277188443402
comment: comment:mint
comment: author-confidence:reliability score: 0.676
data source: intact
participant: Protein uniprotkb P41895 identity 1529029542473
participant: Protein uniprotkb P38902 identity 1529029542472

UnificationXref mint MINT-2200850
type: UnificationXref
id: MINT-2200850
db: mint

UnificationXref mint MINT-2196654
type: UnificationXref
id: MINT-2196654
db: mint

RelationshipXref uniprotkb Q06790 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: Q06790
db: uniprot knowledgebase

RelationshipXref imex IM-15332-7210 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-7210
db: imex

tho2-thp2-2
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-12480 imex-primary
xref: UnificationXref mint MINT-2199374
xref: RelationshipXref intact EBI-7520274 identity
evidence: Evidence 33db6f8a-5205-4301-9d47-e50791561f37 IM-15332-12480 431305 430156
interaction type: physical association
comment: author-confidence:z-score: 2.81286541965921
comment: comment:mint
comment: author-confidence:reliability score: 0.495
data source: intact
participant: Protein uniprotkb O13539 identity 1529029542057
participant: Protein uniprotkb P53552 identity 1529029542056

Evidence 740d997b-c04c-42ad-9c53-3fd2c769bcb9 IM-15332-8412 431433 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm 30855be9-9c0b-4086-b573-62a1bfecd901
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 76da8648-7194-4f29-b716-edd6a87f5d1c
type: ExperimentalForm
experimental feature: ModificationFeature e4801891-286f-4248-8f68-33f3c4d6d63d 431260
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ret1-rpc53-2
type: MolecularInteraction
xref: UnificationXref mint MINT-2195862
xref: RelationshipXref imex IM-15332-10424 imex-primary
xref: RelationshipXref intact EBI-7515709 identity
evidence: Evidence bf7e9a01-0419-4d1f-aefc-2e7afae20558 IM-15332-10424 430525 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.983
comment: comment:mint
comment: author-confidence:z-score: 8.17191158968308
data source: intact
participant: Protein uniprotkb P25441 identity 1529029541667
participant: Protein uniprotkb P22276 identity 1529029541666

RelationshipXref intact EBI-7526714 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7526714
db: intact

RelationshipXref dip DIP-2468N
type: RelationshipXref
id: DIP-2468N
db: database of interacting proteins

ExperimentalForm b50e5d69-af6f-4dd5-ac68-82276d3cb3bc
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7541781 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7541781
db: intact

RelationshipXref intact EBI-7276682 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7276682
db: intact

RelationshipXref interpro IPR007120
type: RelationshipXref
id: IPR007120
db: interpro

RelationshipXref dip DIP-1380N
type: RelationshipXref
id: DIP-1380N
db: database of interacting proteins

rpn2_yeast
type: Protein
evidence: Evidence 96d390f8-e5f1-48ce-b279-4aac35165030 p 433800
entity reference: P32565
name: 26S proteasome regulatory subunit RPN2
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-12481 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12481
db: imex

rpn2_yeast
type: Protein
evidence: Evidence 0bab6d5b-1c5e-47c4-a03d-8ec200ae60bf p 433796
entity reference: P32565
name: 26S proteasome regulatory subunit RPN2
comment: psi-mi participant
data source: intact

ExperimentalForm 599d7ae3-51e5-41a3-b190-9820ce84976c
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref mint MINT-2207312
type: UnificationXref
id: MINT-2207312
db: mint

ExperimentalForm 4adfe140-48cc-4743-b9e5-76be28241c95
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpb8-rpb2-2
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-5984 imex-primary
xref: UnificationXref mint MINT-2204274
xref: RelationshipXref intact EBI-7529515 identity
evidence: Evidence 8435c885-3160-46a6-aa23-f24c9ad23ccb IM-15332-5984 432393 430156
interaction type: physical association
comment: author-confidence:z-score: 4.21679235080696
comment: comment:mint
comment: author-confidence:reliability score: 0.531
data source: intact
participant: Protein uniprotkb P08518 identity 1529029542600
participant: rpab3_yeast

UnificationXref mint MINT-2196636
type: UnificationXref
id: MINT-2196636
db: mint

Evidence 060ee4d8-f2c1-482b-8642-995bf5ebe6fd IM-15332-3596 433537 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref imex IM-15332-5181 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5181
db: imex

RelationshipXref dip DIP-4532N
type: RelationshipXref
id: DIP-4532N
db: database of interacting proteins

Evidence 22d91ec0-535f-454a-a048-8a2fb490ef97 IM-15332-3174 432489 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpc17-rpc82-1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-814 imex-primary
xref: UnificationXref mint MINT-2205529
xref: RelationshipXref intact EBI-7532094 identity
evidence: Evidence 550cff35-fc4a-43e7-931b-2b68fc8cfb07 IM-15332-814 432661 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.989
comment: author-confidence:z-score: 6.40082282556164
comment: comment:mint
data source: intact
participant: Protein uniprotkb P32349 identity 1529029542735
participant: rpc9_yeast

RelationshipXref sgd S000003767
type: RelationshipXref
id: S000003767
db: sgd

UnificationXref mint MINT-2195285
type: UnificationXref
id: MINT-2195285
db: mint

RelationshipXref intact EBI-7515598 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7515598
db: intact

Evidence 14a09b12-f911-4962-bfb7-8febe6319595 IM-15332-2732 430589 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

Evidence b51d5d7f-0ef3-4159-b3a4-a2843008433c IM-15332-3158 430921 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

Evidence 81fd3b2a-ee35-420a-8f74-8da72329c6d2 IM-15332-387 430841 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm d258f275-2a6f-44e9-a17b-cb518b002e37
type: ExperimentalForm
experimental feature: ModificationFeature e50856d7-4565-4be0-a772-9501b0de76ba 432676
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

Evidence e6790922-cab3-4144-8d6c-5aeb17766e47 IM-15332-8825 433845 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref intact EBI-7532904 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7532904
db: intact

RelationshipXref interpro IPR023674
type: RelationshipXref
id: IPR023674
db: interpro

rpb3_yeast
type: Protein
evidence: Evidence 0a9c85f1-028f-4381-8e5d-98ac575e50aa p 432022
entity reference: P16370
name: DNA-directed RNA polymerase II subunit RPB3
comment: psi-mi participant
data source: intact

ExperimentalForm dd3cff8a-ae9f-43de-926a-ccc48ddd77de
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref mint MINT-2196618
type: UnificationXref
id: MINT-2196618
db: mint

RelationshipXref imex IM-15332-12491 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12491
db: imex

glrx5_yeast
type: ProteinReference
sequence: MFLPKFNPIRSFSPILRAKTLLRYQNRMYLSTEIRKAIEDAIESAPVVLFMKGTPEFPKCGFSRATIGLLGNQGVDPAKFAAYNVLEDPELREGIKEFSEWPTIPQLYVNKEFIGGCDVITSMARSGELADLLEEAQALVPEEEEETKDR
xref: RelationshipXref go GO 0051537
xref: RelationshipXref interpro IPR033658
xref: RelationshipXref interpro IPR014434
xref: RelationshipXref go GO 0009055
xref: RelationshipXref uniprotkb D6W3V5 secondary-ac
xref: RelationshipXref rcsb pdb 3GX8
xref: RelationshipXref go GO 0005759
xref: RelationshipXref dip DIP-1352N
xref: RelationshipXref go GO 0046872
xref: RelationshipXref sgd S000005980
xref: RelationshipXref go GO 0034599
xref: RelationshipXref interpro IPR004480
xref: RelationshipXref go GO 0015036
xref: RelationshipXref go GO 0015035
xref: UnificationXref uniprot knowledgebase Q02784
xref: RelationshipXref reactome R-SCE-1362409
xref: RelationshipXref interpro IPR036249
xref: RelationshipXref go GO 0045454
xref: RelationshipXref go GO 0006970
xref: RelationshipXref go GO 0016226
xref: RelationshipXref interpro IPR002109
xref: RelationshipXref intact EBI-29427 identity
xref: RelationshipXref refseq NP 015266 1
xref: RelationshipXref mint Q02784
organism: http://identifiers.org/taxonomy/559292
name: GRX5
name: YPL059W
name: LPE13W
name: Monothiol glutaredoxin-5, mitochondrial

atg11_yeast
type: Protein
evidence: Evidence 529c1249-eb52-4c14-ac55-86f7f504c003 p 433226
entity reference: atg11_yeast
name: Autophagy-related protein 11
comment: psi-mi participant
data source: intact

atg11_yeast
type: Protein
evidence: Evidence b4dcef31-493d-4e4b-bf99-28b54d975500 p 433224
entity reference: atg11_yeast
name: Autophagy-related protein 11
comment: psi-mi participant
data source: intact

ExperimentalForm 3c4aa570-2795-4908-a7fd-0f421b7c4470
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

atg11_yeast
type: Protein
evidence: Evidence 4143a7aa-1d6f-406e-b9c6-3c5104c4250c p 433220
entity reference: atg11_yeast
name: Autophagy-related protein 11
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7535050 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7535050
db: intact

RelationshipXref intact EBI-7525226 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7525226
db: intact

RelationshipXref rcsb pdb 3JCT
type: RelationshipXref
id: 3JCT
db: protein data bank

UnificationXref mint MINT-2195267
type: UnificationXref
id: MINT-2195267
db: mint

ric1-rgp1-4
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-9196 imex-primary
xref: RelationshipXref intact EBI-7518563 identity
xref: UnificationXref mint MINT-2198222
evidence: Evidence c383e689-e97d-4154-b599-601efbfea383 IM-15332-9196 431049 430156
interaction type: physical association
comment: comment:mint
comment: author-confidence:reliability score: 0.99
comment: author-confidence:z-score: 1.33448287967474
data source: intact
participant: Protein uniprotkb P40395 identity 1529029541929
participant: Protein uniprotkb P16664 identity 1529029541928

RelationshipXref rcsb pdb 3JCO
type: RelationshipXref
id: 3JCO
db: protein data bank

rpb3_yeast
type: Protein
evidence: Evidence 7a4f4bfa-3bca-4a15-9f95-a4491aa4d040 p 432044
entity reference: P16370
name: DNA-directed RNA polymerase II subunit RPB3
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7540293 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7540293
db: intact

RelationshipXref imex IM-15332-1222 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1222
db: imex

ExperimentalForm db1672dc-d2dd-4c18-ada1-a809604b9fc5
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 3a412acf-68ce-4b67-a492-110bb64d049f
type: ExperimentalForm
experimental feature: ModificationFeature bfaae5b1-c157-497a-8abc-8925582fa43f 432500
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

UnificationXref uniprot knowledgebase Q04199
type: UnificationXref
id: Q04199
db: uniprot knowledgebase

ExperimentalForm 004b8405-4f65-4ce5-8618-f120fd137eac
type: ExperimentalForm
experimental feature: ModificationFeature 81cec430-4fc4-422d-9bf2-65ceb8b26065 430415
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 17935673-6f93-4c12-883c-dd63eaa4fd7d
type: ExperimentalForm
experimental feature: ModificationFeature 8dbd8d15-eb5e-4716-ab2d-536cdd0af261 432036
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

UnificationXref mint MINT-2196600
type: UnificationXref
id: MINT-2196600
db: mint

RelationshipXref imex IM-15332-3169 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-3169
db: imex

UnificationXref mint MINT-2200094
type: UnificationXref
id: MINT-2200094
db: mint

RelationshipXref imex IM-15332-6784 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-6784
db: imex

rfa1-dna2-1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-7623 imex-primary
xref: UnificationXref mint MINT-2196600
xref: RelationshipXref intact EBI-7516635 identity
evidence: Evidence 9359230d-7f33-464a-84fa-83991c384c7e IM-15332-7623 430689 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 2.67301991285544
comment: comment:mint
comment: author-confidence:reliability score: 0.968
data source: intact
participant: dna2_yeast
participant: rfa1_yeast

RelationshipXref imex IM-15332-7636 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-7636
db: imex

RelationshipXref imex IM-15332-8814 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-8814
db: imex

RelationshipXref intact EBI-7531718 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7531718
db: intact

RelationshipXref imex IM-15332-9618 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-9618
db: imex

hpr1_yeast
type: Protein
evidence: Evidence 500904df-2957-4f34-a3a0-678191112d46 p 431198
entity reference: P17629
name: THO complex subunit HPR1
comment: psi-mi participant
data source: intact

rpa1_yeast
type: Protein
evidence: Evidence 88d085f3-348d-417c-8209-6cdcef52b44d p 431924
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 3JAQ
type: RelationshipXref
id: 3JAQ
db: protein data bank

rpb10-rpa135-1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-394 imex-primary
xref: RelationshipXref intact EBI-7524253 identity
xref: UnificationXref mint MINT-2202075
evidence: Evidence e6bc7dfd-dd17-45ca-bf2e-3feedb6055aa IM-15332-394 431905 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.932
comment: author-confidence:z-score: -0.0162315237506408
comment: comment:mint
data source: intact
participant: rpab5_yeast
participant: Protein uniprotkb P22138 identity 1529029542356

ExperimentalForm 72204f3f-ff0a-4197-9a3c-79158324b3dd
type: ExperimentalForm
experimental feature: ModificationFeature b0ca086e-c888-44cd-b2f7-2376d9bf3716 433488
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpb3-rpo26-1
type: MolecularInteraction
xref: RelationshipXref intact EBI-7527512 identity
xref: UnificationXref mint MINT-2203803
xref: RelationshipXref imex IM-15332-3587 imex-primary
evidence: Evidence aaf2caa4-57f3-4b49-8547-b50762fcdec6 IM-15332-3587 432289 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 1.32377966509729
comment: author-confidence:reliability score: 0.985
comment: comment:mint
data source: intact
participant: Protein uniprotkb P20435 identity 1529029542548
participant: Protein uniprotkb P16370 identity 1529029542549

ExperimentalForm 9578d947-f6eb-4585-8081-21e87aa46a65
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpl1a-rpl10
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-10042 imex-primary
xref: UnificationXref mint MINT-2209688
xref: RelationshipXref intact EBI-7540417 identity
evidence: Evidence ea5fb12e-5da1-4dfb-ad02-a419642bde0a IM-15332-10042 433585 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:z-score: 5.82941394986442
comment: author-confidence:reliability score: 0.681
data source: intact
participant: Protein uniprotkb P53030 identity 1529029543197
participant: Protein uniprotkb P41805 identity 1529029543196

RelationshipXref dip DIP-2327N
type: RelationshipXref
id: DIP-2327N
db: database of interacting proteins

RelationshipXref go GO 0008681
type: RelationshipXref
id: GO:0008681
db: gene ontology

ExperimentalForm 9ae70b6c-356e-4ffe-8858-02e7cb0a3cd8
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpa1_yeast
type: Protein
evidence: Evidence b982b312-2124-41cb-83df-ad73505e764a p 431896
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2207096
type: UnificationXref
id: MINT-2207096
db: mint

UnificationXref mint MINT-2195231
type: UnificationXref
id: MINT-2195231
db: mint

ExperimentalForm 408e29f9-5f9e-4931-a9ec-c4ba46a22e42
type: ExperimentalForm
experimental feature: ModificationFeature 64eea038-0b31-4883-960a-e7ca0340dd44 431216
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-3179 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-3179
db: imex

ExperimentalForm d0aa1758-96f0-42cf-b636-654307854236
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm e839b7ce-bb2e-4b65-b67c-68755ca61714
type: ExperimentalForm
experimental feature: ModificationFeature 28a8e53e-4fa3-40d7-b6e2-d83a1d5614b9 432972
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

Evidence 7ce582df-f3c4-4d84-a725-07110d5bf3ec IM-15332-2345 430801 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref intact EBI-7542436 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7542436
db: intact

RelationshipXref sgd S000003709
type: RelationshipXref
id: S000003709
db: sgd

RelationshipXref imex IM-15332-8824 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-8824
db: imex

RelationshipXref sgd S000003704
type: RelationshipXref
id: S000003704
db: sgd

ExperimentalForm b14832c2-72c1-4414-a0f3-77c08c0d6192
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

Evidence 6effb191-62a6-47a3-89a8-229b955047e0 IM-15332-12492 432757 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref intact EBI-7535881 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7535881
db: intact

rpa190-rpa49-6
type: MolecularInteraction
xref: UnificationXref mint MINT-2201084
xref: RelationshipXref intact EBI-7522788 identity
xref: RelationshipXref imex IM-15332-4391 imex-primary
evidence: Evidence 8a42f09c-21a8-44e0-aaeb-48b29c3ed51c IM-15332-4391 431685 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 8.26474017364909
comment: author-confidence:reliability score: 0.983
comment: comment:mint
data source: intact
participant: Protein uniprotkb Q01080 identity 1529029542247
participant: Protein uniprotkb P10964 identity 1529029542246

ExperimentalForm 0c379d8d-8d0d-4a84-ad35-4b98017a7913
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref uniprot knowledgebase P25441
type: UnificationXref
id: P25441
db: uniprot knowledgebase

rpa1_yeast
type: Protein
evidence: Evidence 08cfef14-00dc-46be-a9b9-b4b43175e5bc p 431854
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2195213
type: UnificationXref
id: MINT-2195213
db: mint

rpn1-rpt4-8
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-11651 imex-primary
xref: RelationshipXref intact EBI-7542531 identity
xref: UnificationXref mint MINT-2210588
evidence: Evidence c25dcbc8-b63a-414f-8110-e6971f510cc5 IM-15332-11651 433785 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.93
comment: comment:homomint
comment: comment:mint
comment: author-confidence:z-score: 0.0326496599803578
data source: intact
participant: prs10_yeast
participant: Protein uniprotkb P38764 identity 1529029543296

ExperimentalForm 3afd8e93-3e42-4757-be2b-c8ab974e38c6
type: ExperimentalForm
experimental feature: ModificationFeature 90aaaa18-9b19-48d3-aa33-e2f36ac1272c 431823
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rco1-sin3-8
type: MolecularInteraction
xref: UnificationXref mint MINT-2195057
xref: RelationshipXref intact EBI-7514900 identity
xref: RelationshipXref imex IM-15332-795 imex-primary
evidence: Evidence b9af2d57-04fc-4776-b565-4f917af04116 IM-15332-795 430349 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.988
comment: comment:mint
comment: author-confidence:z-score: 2.27532070916102
data source: intact
participant: rco1_yeast
participant: Protein uniprotkb P22579 identity 1529029541578

RelationshipXref dip DIP-2324N
type: RelationshipXref
id: DIP-2324N
db: database of interacting proteins

RelationshipXref reactome REACT 346847
type: RelationshipXref
id: REACT_346847
db: reactome

rpa1_yeast
type: Protein
evidence: Evidence bb80fd48-4c3d-473e-bb1a-fbeaceabca93 p 431850
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

ExperimentalForm 8315b032-e9eb-4dc1-806e-d64a8759dc24
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 613d097a-5dbf-478e-b715-4fd5f90587f2
type: ExperimentalForm
experimental feature: ModificationFeature e717b6c1-e934-43da-b7a7-87b25d537c63 430484
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7535520 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7535520
db: intact

Evidence 984605b1-c6ac-4741-a7cb-3b0c5f61cea3 IM-15332-11262 433493 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref intact EBI-7516038 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7516038
db: intact

ExperimentalForm 65cc90f6-e681-4f42-8c7d-bb4c75e12dcf
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref imex IM-15332-4402 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-4402
db: imex

ExperimentalForm 5272b1fc-5871-46a5-8646-bfa5ce2f074c
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref go GO 0008649
type: RelationshipXref
id: GO:0008649
db: gene ontology

RelationshipXref go GO 0033263
type: RelationshipXref
id: GO:0033263
db: gene ontology

rpb10-rpb2
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-2745 imex-primary
xref: UnificationXref mint MINT-2202111
xref: RelationshipXref intact EBI-7524305 identity
evidence: Evidence 4529d0ad-25ad-47e9-8e2f-1e1ae460e781 IM-15332-2745 431913 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.989
comment: comment:mint
comment: author-confidence:z-score: 0.399776953558798
data source: intact
participant: rpab5_yeast
participant: Protein uniprotkb P08518 identity 1529029542360

ExperimentalForm 11812da7-a4e9-4655-9503-2c5a30de03bc
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm de06c682-2177-4319-be7c-997de29804f4
type: ExperimentalForm
experimental feature: ModificationFeature ccf18917-90fa-4f0a-b693-695c193b049f 430468
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

Evidence 53517d2d-ebbb-438e-b24b-73c7399a3007 IM-15332-7191 430849 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpc40-atg11-2
type: MolecularInteraction
xref: UnificationXref mint MINT-2208032
xref: RelationshipXref intact EBI-7536508 identity
xref: RelationshipXref imex IM-15332-3180 imex-primary
evidence: Evidence 33887823-7635-4ad3-97ad-e9428794fb41 IM-15332-3180 433217 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.425
comment: comment:mint
comment: author-confidence:z-score: 0.514775016084111
data source: intact
participant: Protein uniprotkb P07703 identity 1529029543012
participant: atg11_yeast

RelationshipXref rcsb pdb 1BGW
type: RelationshipXref
id: 1BGW
db: protein data bank

ExperimentalForm 62779dde-e865-443e-9901-5eaca0176c0b
type: ExperimentalForm
experimental feature: ModificationFeature 3d8c685c-73fd-4c1f-8c04-afdefc2386c2 431563
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7534434 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7534434
db: intact

spt5_yeast
type: Protein
evidence: Evidence 18790471-dfa9-4a5e-b026-d0b726cab6b9 p 432582
entity reference: P27692
name: Transcription elongation factor SPT5
comment: psi-mi participant
data source: intact

spt5_yeast
type: Protein
evidence: Evidence 085e0aa2-4d28-4c5b-8a5e-0e66b4512dc6 p 432580
entity reference: P27692
name: Transcription elongation factor SPT5
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 2FAK
type: RelationshipXref
id: 2FAK
db: protein data bank

rpa1_yeast
type: Protein
evidence: Evidence 97f9e6c3-a13e-46fa-869d-60e3973846ec p 431810
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

rpa1_yeast
type: Protein
evidence: Evidence 749d5410-5278-4570-b20d-74014dde8f18 p 431806
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 3IZS
type: RelationshipXref
id: 3IZS
db: protein data bank

rpa1_yeast
type: Protein
evidence: Evidence 73c58b2f-e6ef-4a6a-9102-4fd0a3e997b9 p 431802
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

Evidence 8f789f15-49b6-49bc-b602-7819b2745a69 IM-15332-2736 430857 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rfa3-rfa2
type: MolecularInteraction
xref: RelationshipXref intact EBI-7517422 identity
xref: UnificationXref mint MINT-2197321
xref: RelationshipXref imex IM-15332-7191 imex-primary
evidence: Evidence 53517d2d-ebbb-438e-b24b-73c7399a3007 IM-15332-7191 430849 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.989
comment: author-confidence:z-score: 8.64830353258826
comment: comment:mint
data source: intact
participant: Protein uniprotkb P26754 identity 1529029541829
participant: rfa3_yeast

rpa1_yeast
type: Protein
evidence: Evidence 7987fd1f-bdce-4f39-835d-133c90eede32 p 431795
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

ExperimentalForm ebc10380-c7fd-4b2c-a32f-4ae418f70df0
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpn1-rpt1-19
type: MolecularInteraction
xref: UnificationXref mint MINT-2210462
xref: RelationshipXref imex IM-15332-9624 imex-primary
xref: RelationshipXref intact EBI-7542332 identity
evidence: Evidence af76c7ab-a5e3-4698-8d62-3adf2cde805d IM-15332-9624 433757 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.93
comment: comment:homomint
comment: comment:mint
comment: author-confidence:z-score: 6.51173168077263
data source: intact
participant: Protein uniprotkb P33299 identity 1529029543283
participant: Protein uniprotkb P38764 identity 1529029543282

rpa49_yeast
type: Protein
evidence: Evidence a371b0c8-4252-4328-8bb5-7c099f73a917 p 432924
entity reference: Q01080
name: DNA-directed RNA polymerase I subunit RPA49
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-12053 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12053
db: imex

RelationshipXref rcsb pdb 3IZB
type: RelationshipXref
id: 3IZB
db: protein data bank

Evidence aea7b04a-813c-4afe-badf-37a803ff357d IM-15332-8413 431581 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

spt5_yeast
type: Protein
evidence: Evidence 8773ee07-99a3-4d77-a323-f4369df22c05 p 432570
entity reference: P27692
name: Transcription elongation factor SPT5
comment: psi-mi participant
data source: intact

spt5_yeast
type: Protein
evidence: Evidence 53529541-3463-4992-a028-6920f509b4a8 p 432568
entity reference: P27692
name: Transcription elongation factor SPT5
comment: psi-mi participant
data source: intact

rco1-eaf3-4
type: MolecularInteraction
xref: UnificationXref mint MINT-2195213
xref: RelationshipXref imex IM-15332-8406 imex-primary
xref: RelationshipXref intact EBI-7515071 identity
evidence: Evidence b940bcec-bb4e-44ea-9b40-c54af36f57b2 IM-15332-8406 430381 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.989
comment: comment:mint
comment: author-confidence:z-score: 9.79397900396876
data source: intact
participant: rco1_yeast
participant: eaf3_yeast

spt5_yeast
type: Protein
evidence: Evidence 9ebb555e-13a0-41f7-9cfe-aa7c23372dd8 p 432564
entity reference: P27692
name: Transcription elongation factor SPT5
comment: psi-mi participant
data source: intact

Evidence eecd5685-e0e9-43db-b250-7c9d92269ac1 IM-15332-7630 431377 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm 47b81d15-2174-4de6-910b-4242ee18fa90
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpn1-rpn11-4
type: MolecularInteraction
xref: RelationshipXref intact EBI-7541781 identity
xref: RelationshipXref imex IM-15332-4410 imex-primary
xref: UnificationXref mint MINT-2210228
evidence: Evidence c4de2534-524d-4f41-96da-892f5d81a96e IM-15332-4410 433705 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 9.21026100018342
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: rpn11_yeast
participant: Protein uniprotkb P38764 identity 1529029543257

Evidence 72601cf2-34f5-4cf7-96d7-19dcd4db68d6 IM-15332-7196 431213 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm 7b601f12-418e-4aa0-aa7c-6858ae14dc02
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref dip DIP-2735N identity
type: RelationshipXref
relationship type: MI:0356
id: DIP-2735N
db: database of interacting proteins

RelationshipXref go GO 0007017
type: RelationshipXref
id: GO:0007017
db: gene ontology

RelationshipXref rcsb pdb 3J78
type: RelationshipXref
id: 3J78
db: protein data bank

RelationshipXref intact EBI-7521943 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7521943
db: intact

RelationshipXref uniprotkb P20838 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: P20838
db: uniprot knowledgebase

RelationshipXref dip DIP-5255N
type: RelationshipXref
id: DIP-5255N
db: database of interacting proteins

RelationshipXref mint P38859
type: RelationshipXref
id: P38859
db: mint

RelationshipXref sgd S000002309
type: RelationshipXref
id: S000002309
db: sgd

rfa2_yeast
type: Protein
evidence: Evidence 77d5b562-ca3e-4e87-8c2b-50cc5db71c7c p 430774
entity reference: P26754
name: Replication factor A protein 2
comment: psi-mi participant
data source: intact

RelationshipXref sgd S000002306
type: RelationshipXref
id: S000002306
db: sgd

rpg1-nip1-6
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-410 imex-primary
xref: UnificationXref mint MINT-2208950
xref: RelationshipXref intact EBI-7538874 identity
evidence: Evidence 9287d402-c342-43e7-9fc3-6feee9821914 IM-15332-410 433421 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 5.90715604176529
comment: comment:mint
comment: author-confidence:reliability score: 0.968
data source: intact
participant: eif3a_yeast
participant: Protein uniprotkb P32497 identity 1529029543114

RelationshipXref sgd S000002304
type: RelationshipXref
id: S000002304
db: sgd

rfa2_yeast
type: Protein
evidence: Evidence fa3f4731-b231-4c75-802d-a2ece6a3a800 p 430786
entity reference: P26754
name: Replication factor A protein 2
comment: psi-mi participant
data source: intact

rfa2_yeast
type: Protein
evidence: Evidence 2c755c11-7e8c-4c3d-8002-fe40b94fe6f8 p 430790
entity reference: P26754
name: Replication factor A protein 2
comment: psi-mi participant
data source: intact

RelationshipXref go GO 0005758 component
type: RelationshipXref
relationship type: MI:0354
id: GO:0005758
db: gene ontology

RelationshipXref interpro IPR019095
type: RelationshipXref
id: IPR019095
db: interpro

RelationshipXref intact EBI-7515614 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7515614
db: intact

ExperimentalForm d498fe38-77c3-4e4b-8fa8-dcc02c7cdb76
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref go GO 0007265
type: RelationshipXref
id: GO:0007265
db: gene ontology

RelationshipXref go GO 0007264
type: RelationshipXref
id: GO:0007264
db: gene ontology

RelationshipXref imex IM-15332-799 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-799
db: imex

RelationshipXref intact EBI-7523923 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7523923
db: intact

RelationshipXref dip DIP-338N
type: RelationshipXref
id: DIP-338N
db: database of interacting proteins

prs6a_yeast
type: Protein
evidence: Evidence 2fb010d1-bf49-4c3b-a292-67dde279336e p 433784
entity reference: P33297
name: 26S proteasome regulatory subunit 6A
comment: psi-mi participant
data source: intact

RelationshipXref mint Q08971
type: RelationshipXref
id: Q08971
db: mint

rpab1_yeast
type: Protein
evidence: Evidence dd64e35f-934d-41f6-bb8d-7446e022de87 p 431920
entity reference: rpab1_yeast
name: DNA-directed RNA polymerases I, II, and III subunit RPABC1
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-13914 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-13914
db: intact

ExperimentalForm a3491a67-b054-4f50-aeab-c80a3d37de48
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

Evidence a15a8966-2686-4465-a338-a432809d5784 IM-15332-9606 431785 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref mint P38255
type: RelationshipXref
id: P38255
db: mint

RelationshipXref imex IM-15332-3989 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-3989
db: imex

RelationshipXref mint P38251
type: RelationshipXref
id: P38251
db: mint

ExperimentalForm e2d9d01a-06cb-46b1-be63-23e5ac5a4d82
type: ExperimentalForm
experimental feature: ModificationFeature 8f8fd946-c875-432b-ab1a-6276cae6f912 431583
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref rcsb pdb 3J81
type: RelationshipXref
id: 3J81
db: protein data bank

RelationshipXref go GO 2001209
type: RelationshipXref
id: GO:2001209
db: gene ontology

RelationshipXref intact EBI-7527063 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7527063
db: intact

UnificationXref uniprot knowledgebase P40028
type: UnificationXref
id: P40028
db: uniprot knowledgebase

RelationshipXref mint P38249
type: RelationshipXref
id: P38249
db: mint

ExperimentalForm cf2dddfc-2e1c-42c9-84d7-a4d7404f5024
type: ExperimentalForm
experimental feature: ModificationFeature 86077b78-a044-4eeb-949b-0df24b11865c 430695
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref go GO 0032549
type: RelationshipXref
id: GO:0032549
db: gene ontology

RelationshipXref rcsb pdb 3J6Y
type: RelationshipXref
id: 3J6Y
db: protein data bank

prs6a_yeast
type: Protein
evidence: Evidence 82edd321-4b55-4855-89d7-6e951d4f67c7 p 433738
entity reference: P33297
name: 26S proteasome regulatory subunit 6A
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 3J77
type: RelationshipXref
id: 3J77
db: protein data bank

sin3_yeast
type: ProteinReference
sequence: MSQVWHNSNSQSNDVATSNDATGSNERNEKEPSLQGNKPGFVQQQQRITLPSLSALSTKEEDRRDSNGQQALTSHAAHILGYPPPHSNAMPSIATDSALKQPHEYHPRPKSSSSSPSINASLMNAGPAPLPTVGAASFSLSRFDNPLPIKAPVHTEEPKSYNGLQEEEKATQRPQDCKEVPAGVQPADAPDPSSNHADANDDNNNNENSHDEDADYRPLNVKDALSYLEQVKFQFSSRPDIYNLFLDIMKDFKSQAIDTPGVIERVSTLFRGYPILIQGFNTFLPQGYRIECSSNPDDPIRVTTPMGTTTVNNNISPSGRGTTDAQELGSFPESDGNGVQQPSNVPMVPSSVYQSEQNQDQQQSLPLLATSSGLPSIQQPEMPAHRQIPQSQSLVPQEDAKKNVDVEFSQAISYVNKIKTRFADQPDIYKHFLEILQTYQREQKPINEVYAQVTHLFQNAPDLLEDFKKFLPDSSASANQQVQHAQQHAQQQHEAQMHAQAQAQAQAQAQVEQQKQQQQFLYPASGYYGHPSNRGIPQQNLPPIGSFSPPTNGSTVHEAYQDQQHMQPPHFMPLPSIVQHGPNMVHQGIANENPPLSDLRTSLTEQYAPSSIQHQQQHPQSISPIANTQYGDIPVRPEIDLDPSIVPVVPEPTEPIENNISLNEEVTFFEKAKRYIGNKHLYTEFLKILNLYSQDILDLDDLVEKVDFYLGSNKELFTWFKNFVGYQEKTKCIENIVHEKHRLDLDLCEAFGPSYKRLPKSDTFMPCSGRDDMCWEVLNDEWVGHPVWASEDSGFIAHRKNQYEETLFKIEEERHEYDFYIESNLRTIQCLETIVNKIENMTENEKANFKLPPGLGHTSMTIYKKVIRKVYDKERGFEIIDALHEHPAVTAPVVLKRLKQKDEEWRRAQREWNKVWRELEQKVFFKSLDHLGLTFKQADKKLLTTKQLISEISSIKVDQTNKKIHWLTPKPKSQLDFDFPDKNIFYDILCLADTFITHTTAYSNPDKERLKDLLKYFISLFFSISFEKIEESLYSHKQNVSESSGSDDGSSIASRKRPYQQEMSLLDILHRSRYQKLKRSNDEDGKVPQLSEPPEEEPNTIEEEELIDEEAKNPWLTGNLVEEANSQGIIQNRSIFNLFANTNIYIFFRHWTTIYERLLEIKQMNERVTKEINTRSTVTFAKDLDLLSSQLSEMGLDFVGEDAYKQVLRLSRRLINGDLEHQWFEESLRQAYNNKAFKLYTIDKVTQSLVKHAHTLMTDAKTAEIMALFVKDRNASTTSAKDQIIYRLQVRSHMSNTENMFRIEFDKRTLHVSIQYIALDDLTLKEPKADEDKWKYYVTSYALPHPTEGIPHEKLKIPFLERLIEFGQDIDGTEVDEEFSPEGISVSTLKIKIQPITYQLHIENGSYDVFTRKATNKYPTIANDNTQKGMVSQKKELISKFLDCAVGLRNNLDEAQKLSMQKKWENLKDSIAKTSAGNQGIESETEKGKITKQEQSDNLDSSTASVLPASITTVPQDDNIETTGNTESSDKGAKIQ
xref: RelationshipXref uniprotkb D6W263 secondary-ac
xref: RelationshipXref go GO 0042802
xref: RelationshipXref interpro IPR003822
xref: RelationshipXref go GO 0031939
xref: RelationshipXref interpro IPR013194
xref: RelationshipXref refseq NP 014639 1
xref: RelationshipXref interpro IPR031693
xref: RelationshipXref go GO 0070822
xref: RelationshipXref go GO 0000117
xref: RelationshipXref go GO 0030174
xref: RelationshipXref go GO 0061188
xref: RelationshipXref go GO 0061186
xref: RelationshipXref mint P22579
xref: RelationshipXref interpro IPR036600
xref: RelationshipXref go GO 0000122
xref: RelationshipXref go GO 0016479
xref: RelationshipXref reactome R-SCE-8936459
xref: RelationshipXref go GO 0006303
xref: RelationshipXref sgd S000005364
xref: RelationshipXref go GO 0045944
xref: RelationshipXref go GO 0016575
xref: UnificationXref uniprot knowledgebase P22579
xref: RelationshipXref go GO 0051038
xref: RelationshipXref go GO 0061587
xref: RelationshipXref go GO 0033698
xref: RelationshipXref go GO 0032221
xref: RelationshipXref intact EBI-17160 identity
xref: RelationshipXref go GO 0001106
xref: RelationshipXref dip DIP-597N
xref: RelationshipXref go GO 0006351
xref: RelationshipXref go GO 0003714
xref: RelationshipXref go GO 0051301
xref: RelationshipXref go GO 0003713
xref: RelationshipXref go GO 0061408
xref: RelationshipXref uniprotkb Q08049 secondary-ac
organism: http://identifiers.org/taxonomy/559292
name: GAM2
name: RPD1
name: UME4
name: SIN3
name: SDI1
name: YOL004W
name: SDS16
name: CPE1
name: Transcriptional regulatory protein SIN3

rpd3-eaf3-2
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-12064 imex-primary
xref: RelationshipXref intact EBI-7538408 identity
xref: UnificationXref mint MINT-2208698
evidence: Evidence 3eae7d57-647d-4891-a84d-3154ff0ab7cf IM-15332-12064 433365 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.99
comment: author-confidence:z-score: 9.2676600728606
data source: intact
participant: rpd3_yeast
participant: Protein uniprotkb Q12432 identity 1529029543086

ExperimentalForm 438dee3f-502d-4a92-bf09-bd738b7945fb
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm ddda4d27-b4dd-47c1-865e-dabb68fb5ce3
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref go GO 0007232
type: RelationshipXref
id: GO:0007232
db: gene ontology

RelationshipXref imex IM-15332-2761 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-2761
db: imex

rpa135-rpc34-3
type: MolecularInteraction
xref: RelationshipXref intact EBI-7521796 identity
xref: UnificationXref mint MINT-2200382
xref: RelationshipXref imex IM-15332-10851 imex-primary
evidence: Evidence 5ed02a03-83de-451f-b4fa-41f40c7146d6 IM-15332-10851 431529 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 0.110410616050569
comment: author-confidence:reliability score: 0.688
comment: comment:mint
data source: intact
participant: Protein uniprotkb P22138 identity 1529029542168
participant: rpc6_yeast

ExperimentalForm 2c31e9eb-af89-4b57-9de6-b8b3848415eb
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref uniprotkb D6VVK9 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VVK9
db: uniprot knowledgebase

RelationshipXref imex IM-15332-12479 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12479
db: imex

UnificationXref mint MINT-2202849
type: UnificationXref
id: MINT-2202849
db: mint

Evidence 9a57a5a7-acd1-4140-9856-c5bea13f4b15 IM-15332-11633 430945 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref mint MINT-2208698
type: UnificationXref
id: MINT-2208698
db: mint

RelationshipXref intact EBI-7538346 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7538346
db: intact

RelationshipXref imex IM-15332-9198 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-9198
db: imex

rim13-cka1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-8017 imex-primary
xref: UnificationXref mint MINT-2198438
xref: RelationshipXref intact EBI-7518811 identity
evidence: Evidence c4f0ee77-96aa-41da-87a4-a19d928349a4 IM-15332-8017 431097 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.635
comment: author-confidence:z-score: 8.6128651907372
comment: comment:mint
data source: intact
participant: csk21_yeast
participant: rim13_yeast

ExperimentalForm ced7788e-7698-474c-b6bd-e47f4eb44f3d
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7535535 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7535535
db: intact

ExperimentalForm 8064931e-82ed-4320-ae71-beb2b06133d2
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7539786 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7539786
db: intact

RelationshipXref intact EBI-7536018 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7536018
db: intact

UnificationXref mint MINT-2208680
type: UnificationXref
id: MINT-2208680
db: mint

RelationshipXref interpro IPR033524
type: RelationshipXref
id: IPR033524
db: interpro

RelationshipXref rcsb pdb 2EXU
type: RelationshipXref
id: 2EXU
db: protein data bank

RelationshipXref go GO 1900364
type: RelationshipXref
id: GO:1900364
db: gene ontology

ExperimentalForm da246c30-9b23-45d3-86c4-8cd0949f2400
type: ExperimentalForm
experimental feature: ModificationFeature dd9fd95b-48fa-4b55-9588-b1950c377b0b 432416
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

Evidence 9287d402-c342-43e7-9fc3-6feee9821914 IM-15332-410 433421 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm 3d6e5221-da64-47a7-8cd6-8e7e0de3410a
type: ExperimentalForm
experimental feature: ModificationFeature 22296099-766f-4daf-887a-13a82c23fd8e 433540
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpd3-sds3
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-5597 imex-primary
xref: UnificationXref mint MINT-2208320
xref: RelationshipXref intact EBI-7537679 identity
evidence: Evidence e42a263c-7428-40a7-832b-b5bf1ecbbaa7 IM-15332-5597 433281 430156
interaction type: physical association
comment: author-confidence:z-score: 4.67532964313551
comment: author-confidence:reliability score: 0.764
comment: comment:mint
data source: intact
participant: Protein uniprotkb P40505 identity 1529029543044
participant: rpd3_yeast

rpb10-rpo21-2
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-8812 imex-primary
xref: RelationshipXref intact EBI-7525242 identity
xref: UnificationXref mint MINT-2202633
evidence: Evidence fe930922-e356-4086-b0e1-25aa9e56d10f IM-15332-8812 432029 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.968
comment: author-confidence:z-score: 0.0824763392091503
data source: intact
participant: rpab5_yeast
participant: Protein uniprotkb P04050 identity 1529029542419

rpab1_yeast
type: Protein
evidence: Evidence 8832944a-e8d5-4e7b-bcd3-91797837cd95 p 431814
entity reference: rpab1_yeast
name: DNA-directed RNA polymerases I, II, and III subunit RPABC1
comment: psi-mi participant
data source: intact

RelationshipXref uniprotkb D6W142 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6W142
db: uniprot knowledgebase

rpb8-ret1-1
type: MolecularInteraction
xref: RelationshipXref intact EBI-7528110 identity
xref: UnificationXref mint MINT-2203985
xref: RelationshipXref imex IM-15332-7205 imex-primary
evidence: Evidence 9efe9916-164a-4448-8971-4ee2820ce0a7 IM-15332-7205 432329 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 0.981261632832834
comment: author-confidence:reliability score: 0.85
comment: comment:mint
data source: intact
participant: rpab3_yeast
participant: Protein uniprotkb P22276 identity 1529029542568

rim11-nap1-3
type: MolecularInteraction
xref: UnificationXref mint MINT-2198420
xref: RelationshipXref intact EBI-7518796 identity
xref: RelationshipXref imex IM-15332-1576 imex-primary
evidence: Evidence 482230b8-a2f6-4bfe-9a60-312cc1bdd3e9 IM-15332-1576 431093 430156
interaction type: physical association
comment: author-confidence:z-score: 9.83373497680238
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P25293 identity 1529029541950
participant: Protein uniprotkb P38615 identity 1529029541951

ExperimentalForm 5f5756e9-2e66-45f2-90ec-cdd0849891f2
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref mint MINT-2210012
type: UnificationXref
id: MINT-2210012
db: mint

rpab3_yeast
type: Protein
evidence: Evidence 121c9d6a-c559-4b9f-bd3f-fef2e4135598 p 432391
entity reference: P20436
name: DNA-directed RNA polymerases I, II, and III subunit RPABC3
comment: psi-mi participant
data source: intact

prs6a_yeast
type: Protein
evidence: Evidence 30feffda-7ea5-467b-8e04-a874e47bd4e0 p 433660
entity reference: P33297
name: 26S proteasome regulatory subunit 6A
comment: psi-mi participant
data source: intact

rpab3_yeast
type: Protein
evidence: Evidence 69f5bdc1-d787-48e2-b444-9af55b2eea4e p 432386
entity reference: P20436
name: DNA-directed RNA polymerases I, II, and III subunit RPABC3
comment: psi-mi participant
data source: intact

rpab1_yeast
type: Protein
evidence: Evidence c32666ad-b801-4194-bab5-6820a92b3225 p 431804
entity reference: rpab1_yeast
name: DNA-directed RNA polymerases I, II, and III subunit RPABC1
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-6363 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-6363
db: imex

RelationshipXref interpro IPR019024
type: RelationshipXref
id: IPR019024
db: interpro

RelationshipXref intact EBI-15281 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-15281
db: intact

ExperimentalForm 4cd65e96-dd1e-4ee4-8b7c-f434cdc58f43
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref dip DIP-681N
type: RelationshipXref
id: DIP-681N
db: database of interacting proteins

UnificationXref mint MINT-2208662
type: UnificationXref
id: MINT-2208662
db: mint

rco1-htb2-3
type: MolecularInteraction
xref: UnificationXref mint MINT-2195393
xref: RelationshipXref imex IM-15332-5164 imex-primary
xref: RelationshipXref intact EBI-7515269 identity
evidence: Evidence 58a4ecff-e523-41d4-b4d5-e685fa983aee IM-15332-5164 430421 430156
interaction type: physical association
comment: author-confidence:z-score: 1.2026064636314
comment: comment:mint
comment: author-confidence:reliability score: 0.409
data source: intact
participant: rco1_yeast
participant: Protein uniprotkb P02294 identity 1529029541615

rfa1-rfa3-2
type: MolecularInteraction
xref: RelationshipXref intact EBI-7516620 identity
xref: RelationshipXref imex IM-15332-8011 imex-primary
xref: UnificationXref mint MINT-2196582
evidence: Evidence bba4ffc8-03ae-40cc-8c19-a388150ea834 IM-15332-8011 430685 430156
interaction type: physical association
comment: author-confidence:z-score: 1.39838475343827
comment: author-confidence:reliability score: 0.988
comment: comment:mint
data source: intact
participant: rfa1_yeast
participant: Protein uniprotkb P26755 identity 1529029541747

RelationshipXref go GO 0035196
type: RelationshipXref
id: GO:0035196
db: gene ontology

UnificationXref mint MINT-2197988
type: UnificationXref
id: MINT-2197988
db: mint

RelationshipXref dip DIP-8047N
type: RelationshipXref
id: DIP-8047N
db: database of interacting proteins

rpc7_yeast
type: Protein
evidence: Evidence 1eaf167d-a1c8-47fa-96e0-27b3a3e752c9 p 432646
entity reference: P17890
name: DNA-directed RNA polymerase III subunit RPC7
comment: psi-mi participant
data source: intact

rpab3_yeast
type: Protein
evidence: Evidence 13edc9cf-5e4b-4bf7-bf06-63b15c8b84bf p 432366
entity reference: P20436
name: DNA-directed RNA polymerases I, II, and III subunit RPABC3
comment: psi-mi participant
data source: intact

rpab3_yeast
type: Protein
evidence: Evidence 75bad01e-e79a-4a9e-99a2-cf47bc0668f8 p 432362
entity reference: P20436
name: DNA-directed RNA polymerases I, II, and III subunit RPABC3
comment: psi-mi participant
data source: intact

RelationshipXref uniprotkb D3DLX5 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D3DLX5
db: uniprot knowledgebase

rpab3_yeast
type: Protein
evidence: Evidence 7f621eeb-da07-4124-a86f-9f145e3ad96c p 432355
entity reference: P20436
name: DNA-directed RNA polymerases I, II, and III subunit RPABC3
comment: psi-mi participant
data source: intact

rim1_yeast
type: Protein
evidence: Evidence 7ea1e3de-41f8-48ee-b1a2-10540ac88c20 p 431071
entity reference: P32445
name: Single-stranded DNA-binding protein RIM1, mitochondrial
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 3J1N
type: RelationshipXref
id: 3J1N
db: protein data bank

rim1_yeast
type: Protein
evidence: Evidence 77e7fe77-22c7-4adf-a6c8-36b5d3f578a3 p 431066
entity reference: P32445
name: Single-stranded DNA-binding protein RIM1, mitochondrial
comment: psi-mi participant
data source: intact

rpn12_yeast
type: Protein
evidence: Evidence 6d1c902d-45d0-46b1-aa10-4d156c600018 p 433806
entity reference: P32496
name: 26S proteasome regulatory subunit RPN12
comment: psi-mi participant
data source: intact

RelationshipXref refseq NP 010524 3
type: RelationshipXref
id: NP_010524.3
db: refseq

RelationshipXref refseq NP 009898 1
type: RelationshipXref
id: NP_009898.1
db: refseq

RelationshipXref intact EBI-7518140 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7518140
db: intact

RelationshipXref uniprotkb D6W3X1 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6W3X1
db: uniprot knowledgebase

RelationshipXref refseq NP 010186 1
type: RelationshipXref
id: NP_010186.1
db: refseq

RelationshipXref refseq NP 009404 1
type: RelationshipXref
id: NP_009404.1
db: refseq

rpab3_yeast
type: Protein
evidence: Evidence 85de4494-0757-4381-98d4-73136ba3ace5 p 432339
entity reference: P20436
name: DNA-directed RNA polymerases I, II, and III subunit RPABC3
comment: psi-mi participant
data source: intact

Evidence 4aa97aac-278e-45f8-a37f-72120901ef19 IM-15332-7624 430713 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref mint MINT-2197970
type: UnificationXref
id: MINT-2197970
db: mint

RelationshipXref rcsb pdb 2EUD
type: RelationshipXref
id: 2EUD
db: protein data bank

ExperimentalForm 3fcdad91-5529-460f-8834-394ed10c1ab6
type: ExperimentalForm
experimental feature: ModificationFeature b782f6cb-001b-48d3-803e-e1a33e067b5b 430663
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

UnificationXref uniprot knowledgebase P10964
type: UnificationXref
id: P10964
db: uniprot knowledgebase

RelationshipXref interpro IPR011488
type: RelationshipXref
id: IPR011488
db: interpro

UnificationXref mint MINT-2208644
type: UnificationXref
id: MINT-2208644
db: mint

ExperimentalForm e8cc4383-c802-4fde-871b-5f5ac3ac8a7d
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm 462321f0-4aa0-4b05-8f7e-390ed0621683
type: ExperimentalForm
experimental feature: ModificationFeature 4e00ae1f-846d-4866-ba7e-9f745af34b52 433275
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

Evidence d246fec3-5d08-4ce4-a16b-ee112f077e48 IM-15332-12885 432793 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref rcsb pdb 1YPP
type: RelationshipXref
id: 1YPP
db: protein data bank

RelationshipXref imex IM-15332-2363 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-2363
db: imex

ExperimentalForm bcf56310-5358-4220-bc6a-f69ee1a76699
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref uniprot knowledgebase P47821
type: UnificationXref
id: P47821
db: uniprot knowledgebase

rpab3_yeast
type: Protein
evidence: Evidence 392c545d-5578-49c9-b20e-f6efe6160b88 p 432331
entity reference: P20436
name: DNA-directed RNA polymerases I, II, and III subunit RPABC3
comment: psi-mi participant
data source: intact

ExperimentalForm 46088f2b-e580-4cfa-834b-bd6c0a4e9164
type: ExperimentalForm
experimental feature: ModificationFeature 6358b182-e06c-41b3-9266-620a3420d9ed 431315
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpab3_yeast
type: Protein
evidence: Evidence 1ba02438-2d78-45b1-adaa-b82132854e37 p 432327
entity reference: P20436
name: DNA-directed RNA polymerases I, II, and III subunit RPABC3
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2207294
type: UnificationXref
id: MINT-2207294
db: mint

ExperimentalForm 1c19cd64-847f-43e5-ae53-d18295b4e731
type: ExperimentalForm
experimental feature: ModificationFeature fb132bc2-0d30-4a7c-ae30-67858bf5a085 432064
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-2747 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-2747
db: imex

ExperimentalForm a2824d61-fdba-4689-a3ff-0034f6ebf45b
type: ExperimentalForm
experimental feature: ModificationFeature 301319ac-af03-4f0d-8031-aadd742c3344 433360
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm e770cfc4-97ec-44c6-8048-d8478c5b9cf2
type: ExperimentalForm
experimental feature: ModificationFeature dfc89db2-6593-41f0-8cf2-fb6e1cd411f6 431932
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpn2_yeast
type: Protein
evidence: Evidence 750b99ab-3a21-4cd1-999c-7f52e1076a90 p 433746
entity reference: P32565
name: 26S proteasome regulatory subunit RPN2
comment: psi-mi participant
data source: intact

rlf2_yeast
type: Protein
evidence: Evidence 29f46032-0b1b-4669-979b-aab5946b7706 p 431135
entity reference: Q12495
name: Chromatin assembly factor 1 subunit p90
comment: psi-mi participant
data source: intact

ExperimentalForm df4b8e69-ba72-41be-a092-658b1c9fa5d7
type: ExperimentalForm
experimental feature: ModificationFeature 516f784e-87b3-44a5-875c-d8ba4016b9b9 432328
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref uniprotkb D6VWN9 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VWN9
db: uniprot knowledgebase

RelationshipXref intact EBI-7537467 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7537467
db: intact

ExperimentalForm 04c09edc-639e-4427-9fcf-4321a8823a76
type: ExperimentalForm
experimental feature: ModificationFeature a38520c3-9ae9-4bbd-bc8f-aabbc11504d2 432751
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7521556 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7521556
db: intact

UnificationXref mint MINT-2197952
type: UnificationXref
id: MINT-2197952
db: mint

prs10_yeast
type: Protein
evidence: Evidence 6687a6b4-41ef-44b1-b8ff-704c75989a74 p 433912
entity reference: P53549
name: 26S proteasome subunit RPT4
comment: psi-mi participant
data source: intact

RelationshipXref intact MINT-665405 intact-secondary
type: RelationshipXref
relationship type: RelationshipTypeVocabulary c02affb5da4a12b7480930287d7efe16
id: MINT-665405
db: intact

UnificationXref mint MINT-2208626
type: UnificationXref
id: MINT-2208626
db: mint

ExperimentalForm 239de7e9-8fc8-4fd2-abd0-13c81f26c5f0
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

msi1_yeast
type: Protein
evidence: Evidence 16b93b9c-6826-4549-8de8-5af5084c554b p 431134
entity reference: P13712
name: Chromatin assembly factor 1 subunit p50
comment: psi-mi participant
data source: intact

ExperimentalForm 8d7c7641-fe61-42a8-b8a6-4932ae8124b9
type: ExperimentalForm
experimental feature: ModificationFeature cff62e9e-214d-4ee5-9917-b61fbd93497d 431992
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-7524320 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7524320
db: intact

RelationshipXref intact EBI-15798 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-15798
db: intact

UnificationXref mint MINT-2207276
type: UnificationXref
id: MINT-2207276
db: mint

RelationshipXref imex IM-15332-5170 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5170
db: imex

idhh_yeast
type: Protein
evidence: Evidence f8f55113-183f-4685-adfa-8f4ab9f1c7c2 p 430480
entity reference: P53982
name: Isocitrate dehydrogenase [NADP]
comment: psi-mi participant
data source: intact

rpc1_yeast
type: ProteinReference
sequence: MKEVVVSETPKRIKGLEFSALSAADIVAQSEVEVSTRDLFDLEKDRAPKANGALDPKMGVSSSSLECATCHGNLASCHGHFGHLKLALPVFHIGYFKATIQILQGICKNCSAILLSETDKRQFLHELRRPGVDNLRRMGILKKILDQCKKQRRCLHCGALNGVVKKAAAGAGSAALKIIHDTFRWVGKKSAPEKDIWVGEWKEVLAHNPELERYVKRCMDDLNPLKTLNLFKQIKSADCELLGIDATVPSGRPETYIWRYLPAPPVCIRPSVMMQDSPASNEDDLTVKLTEIVWTSSLIKAGLDKGISINNMMEHWDYLQLTVAMYINSDSVNPAMLPGSSNGGGKVKPIRGFCQRLKGKQGRFRGNLSGKRVDFSGRTVISPDPNLSIDEVAVPDRVAKVLTYPEKVTRYNRHKLQELIVNGPNVHPGANYLLKRNEDARRNLRYGDRMKLAKNLQIGDVVERHLEDGDVVLFNRQPSLHRLSILSHYAKIRPWRTFRLNECVCTPYNADFDGDEMNLHVPQTEEARAEAINLMGVKNNLLTPKSGEPIIAATQDFITGSYLISHKDSFYDRATLTQLLSMMSDGIEHFDIPPPAIMKPYYLWTGKQVFSLLIKPNHNSPVVINLDAKNKVFVPPKSKSLPNEMSQNDGFVIIRGSQILSGVMDKSVLGDGKKHSVFYTILRDYGPQEAANAMNRMAKLCARFLGNRGFSIGINDVTPADDLKQKKEELVEIAYHKCDELITLFNKGELETQPGCNEEQTLEAKIGGLLSKVREEVGDVCINELDNWNAPLIMATCGSKGSTLNVSQMVAVVGQQIISGNRVPDGFQDRSLPHFPKNSKTPQSKGFVRNSFFSGLSPPEFLFHAISGREGLVDTAVKTAETGYMSRRLMKSLEDLSCQYDNTVRTSANGIVQFTYGGDGLDPLEMEGNAQPVNFNRSWDHAYNITFNNQDKGLLPYAIMETANEILGPLEERLVRYDNSGCLVKREDLNKAEYVDQYDAERDFYHSLREYINGKATALANLRKSRGMLGLLEPPAKELQGIDPDETVPDNVKTSVSQLYRISEKSVRKFLEIALFKYRKARLEPGTAIGAIGAQSIGEPGTQMTLKTFHFAGVASMNVTLGVPRIKEIINASKVISTPIINAVLVNDNDERAARVVKGRVEKTLLSDVAFYVQDVYKDNLSFIQVRIDLGTIDKLQLELTIEDIAVAITRASKLKIQASDVNIIGKDRIAINVFPEGYKAKSISTSAKEPSENDVFYRMQQLRRALPDVVVKGLPDISRAVINIRDDGKRELLVEGYGLRDVMCTDGVIGSRTTTNHVLEVFSVLGIEAARYSIIREINYTMSNHGMSVDPRHIQLLGDVMTYKGEVLGITRFGLSKMRDSVLQLASFEKTTDHLFDAAFYMKKDAVEGVSECIILGQTMSIGTGSFKVVKGTNISEKDLVPKRCLFESLSNEAALKAN
xref: RelationshipXref reactome R-SCE-674695
xref: RelationshipXref go GO 0042797
xref: RelationshipXref refseq NP 014759 1
xref: RelationshipXref interpro IPR038120
xref: RelationshipXref interpro IPR000722
xref: RelationshipXref go GO 0003899
xref: RelationshipXref intact EBI-15810 identity
xref: RelationshipXref dip DIP-612N
xref: RelationshipXref go GO 0005654
xref: RelationshipXref rcsb pdb 5FJA
xref: RelationshipXref go GO 0046872
xref: RelationshipXref rcsb pdb 6F44
xref: RelationshipXref uniprotkb D6W2H5 secondary-ac
xref: RelationshipXref rcsb pdb 6F42
xref: RelationshipXref rcsb pdb 6F41
xref: RelationshipXref rcsb pdb 6F40
xref: RelationshipXref rcsb pdb 5FJ8
xref: RelationshipXref interpro IPR007066
xref: RelationshipXref reactome R-SCE-75953
xref: RelationshipXref sgd S000005642
xref: RelationshipXref reactome R-SCE-72165
xref: RelationshipXref reactome R-SCE-6781823
xref: RelationshipXref reactome R-SCE-6782135
xref: RelationshipXref interpro IPR007083
xref: UnificationXref uniprot knowledgebase P04051
xref: RelationshipXref interpro IPR035698
xref: RelationshipXref interpro IPR035697
xref: RelationshipXref reactome R-SCE-77075
xref: RelationshipXref rcsb pdb 6EU3
xref: RelationshipXref rcsb pdb 5FJ9
xref: RelationshipXref rcsb pdb 6EU1
xref: RelationshipXref rcsb pdb 6EU0
xref: RelationshipXref interpro IPR007081
xref: RelationshipXref interpro IPR007080
xref: RelationshipXref reactome R-SCE-6796648
xref: RelationshipXref reactome R-SCE-73779
xref: RelationshipXref reactome R-SCE-76042
xref: RelationshipXref reactome R-SCE-73776
xref: RelationshipXref reactome R-SCE-72086
xref: RelationshipXref go GO 0003677
xref: RelationshipXref go GO 0006386
xref: RelationshipXref go GO 0005666
xref: RelationshipXref mint P04051
xref: RelationshipXref reactome R-SCE-113418
xref: RelationshipXref interpro IPR006592
xref: RelationshipXref reactome R-SCE-6782210
xref: RelationshipXref rcsb pdb 6EU2
organism: http://identifiers.org/taxonomy/559292
name: RPC1
name: DNA-directed RNA polymerase III largest subunit
name: RPO31
name: RNA polymerase III subunit C160
name: YOR116C
name: RPC160
name: DNA-directed RNA polymerase III subunit RPC1
name: YOR3254C
name: O3254

RelationshipXref imex IM-15332-9195 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-9195
db: imex

RelationshipXref dip DIP-4663N
type: RelationshipXref
id: DIP-4663N
db: database of interacting proteins

RelationshipXref imex IM-15332-1953 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1953
db: imex

RelationshipXref intact EBI-7516667 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7516667
db: intact

rpb8-rpb2-3
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-10030 imex-primary
xref: UnificationXref mint MINT-2204328
xref: RelationshipXref intact EBI-7529763 identity
evidence: Evidence 35be1cc8-9a41-4070-8336-0bf8c7783b31 IM-15332-10030 432405 430156
interaction type: physical association
comment: author-confidence:z-score: 0.249415914947857
comment: author-confidence:reliability score: 0.531
comment: comment:mint
data source: intact
participant: rpab3_yeast
participant: Protein uniprotkb P08518 identity 1529029542606

RelationshipXref intact EBI-7536478 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7536478
db: intact

UnificationXref mint MINT-2197934
type: UnificationXref
id: MINT-2197934
db: mint

ExperimentalForm d320bb05-852c-452d-a474-f50d6964f54c
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref mint MINT-2208608
type: UnificationXref
id: MINT-2208608
db: mint

ExperimentalForm 957e1ece-c77a-469e-a41b-4bd3adc349e9
type: ExperimentalForm
experimental feature: ModificationFeature bd409362-2262-4c2a-98d1-5070c24fef24 431495
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref refseq NP 014638 1
type: RelationshipXref
id: NP_014638.1
db: refseq

RelationshipXref imex IM-15332-410 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-410
db: imex

rim4-ste50
type: MolecularInteraction
xref: RelationshipXref intact EBI-7518876 identity
xref: UnificationXref mint MINT-2198492
xref: RelationshipXref imex IM-15332-3160 imex-primary
evidence: Evidence 10dae82a-cee4-485a-a5fe-dac0187c7e02 IM-15332-3160 431109 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.617
comment: author-confidence:z-score: 2.11867261815233
comment: comment:mint
data source: intact
participant: rim4_yeast
participant: Protein uniprotkb P25344 identity 1529029541958

rpn2_yeast
type: Protein
evidence: Evidence 8b4e186f-9be3-429c-ac64-a09515e7c958 p 433684
entity reference: P32565
name: 26S proteasome regulatory subunit RPN2
comment: psi-mi participant
data source: intact

ExperimentalForm da7e833b-787b-4770-acc6-f3a88eccb5d7
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref mint MINT-2207258
type: UnificationXref
id: MINT-2207258
db: mint

ExperimentalForm efbbd9e1-8540-4849-93da-bd8359a945a5
type: ExperimentalForm
experimental feature: ModificationFeature 7ffeaa1a-285d-401b-a11c-4ddc83cf80e6 433683
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref intact EBI-16985 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-16985
db: intact

RelationshipXref intact EBI-8666 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-8666
db: intact

prs10_yeast
type: Protein
evidence: Evidence f8b1a2c9-1dde-4fbe-a32b-1e376ec42069 p 433846
entity reference: P53549
name: 26S proteasome subunit RPT4
comment: psi-mi participant
data source: intact

prs10_yeast
type: Protein
evidence: Evidence d966d1d1-d09e-411b-ba4a-97cfb05bc3ac p 433844
entity reference: P53549
name: 26S proteasome subunit RPT4
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7516620 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7516620
db: intact

rim11-nap1-1
type: MolecularInteraction
xref: UnificationXref mint MINT-2198384
xref: RelationshipXref imex IM-15332-7195 imex-primary
xref: RelationshipXref intact EBI-7518743 identity
evidence: Evidence 98a62dd6-47ee-417c-b85d-ee6eea513457 IM-15332-7195 431085 430156
interaction type: physical association
comment: comment:mint
comment: author-confidence:reliability score: 0.99
comment: author-confidence:z-score: 9.61641810450189
data source: intact
participant: rim11_yeast
participant: Protein uniprotkb P25293 identity 1529029541946

RelationshipXref intact EBI-7521417 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7521417
db: intact

RelationshipXref uniprotkb D6VX52 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VX52
db: uniprot knowledgebase

Evidence 1c0bd9a8-eb59-493e-81dd-87498a2e8fcb IM-15332-12877 431777 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref rcsb pdb 2F16
type: RelationshipXref
id: 2F16
db: protein data bank

rpg1-prt1-9
type: MolecularInteraction
xref: RelationshipXref intact EBI-7539365 identity
xref: RelationshipXref imex IM-15332-1223 imex-primary
xref: UnificationXref mint MINT-2209202
evidence: Evidence 23482e7a-9beb-4a0f-a78a-6d3cb23f260c IM-15332-1223 433477 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 3.133670966846
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P38249 identity 1529029543143
participant: Protein uniprotkb P06103 identity 1529029543142

ExperimentalForm 18daf922-f8b2-473b-b56a-1f92d194516e
type: ExperimentalForm
experimental feature: ModificationFeature c988bf33-e984-432b-b9c7-47a7fd0c6359 430567
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-10443 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-10443
db: imex

UnificationXref mint MINT-2197916
type: UnificationXref
id: MINT-2197916
db: mint

ExperimentalForm 58fc7d66-c943-4671-a46e-989b2cc8a569
type: ExperimentalForm
experimental feature: ModificationFeature f30b050e-cd0d-499a-b919-e05c598f905d 433748
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

Evidence a644801d-90b5-41b6-8fbc-eeda47c20237 IM-15332-3990 432505 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref mint MINT-2207240
type: UnificationXref
id: MINT-2207240
db: mint

RelationshipXref mint Q06142
type: RelationshipXref
id: Q06142
db: mint

RelationshipXref imex IM-15332-2737 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-2737
db: imex

ExperimentalForm a897c218-6e2f-47df-9beb-ba69d007c19b
type: ExperimentalForm
experimental feature: ModificationFeature ac3c7caa-3aaa-4b5c-9fe0-0a487eb0a947 432399
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm ba9d806c-dd00-442c-8608-1bee9f0a3756
type: ExperimentalForm
experimental feature: ModificationFeature 61efd7a9-7cca-49e5-981f-9a4fab5389e0 433899
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpb9-rpb2-11
type: MolecularInteraction
xref: RelationshipXref intact EBI-7531207 identity
xref: RelationshipXref imex IM-15332-9208 imex-primary
xref: UnificationXref mint MINT-2204891
evidence: Evidence f9f7f9cf-421a-4379-913b-2879aaa32803 IM-15332-9208 432525 430156
interaction type: physical association
comment: author-confidence:z-score: 0.181534492102342
comment: author-confidence:reliability score: 0.989
comment: comment:mint
data source: intact
participant: Protein uniprotkb P08518 identity 1529029542666
participant: Protein uniprotkb P27999 identity 1529029542667

RelationshipXref interpro IPR011425
type: RelationshipXref
id: IPR011425
db: interpro

UnificationXref mint MINT-2196564
type: UnificationXref
id: MINT-2196564
db: mint

rpn2_yeast
type: Protein
evidence: Evidence 9ee9d873-764b-40c1-a4b4-464d4b9fc39e p 433644
entity reference: P32565
name: 26S proteasome regulatory subunit RPN2
comment: psi-mi participant
data source: intact

UnificationXref uniprot knowledgebase P42841
type: UnificationXref
id: P42841
db: uniprot knowledgebase

RelationshipXref intact EBI-7539754 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7539754
db: intact

RelationshipXref uniprotkb D6VRT6 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VRT6
db: uniprot knowledgebase

RelationshipXref intact EBI-7531141 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7531141
db: intact

RelationshipXref intact EBI-7533029 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7533029
db: intact

RelationshipXref intact EBI-7516974 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7516974
db: intact

rpa190-rpo26-4
type: MolecularInteraction
xref: UnificationXref mint MINT-2200778
xref: RelationshipXref intact EBI-7522433 identity
xref: RelationshipXref imex IM-15332-809 imex-primary
evidence: Evidence 51d96d66-c3d3-47cc-bddb-62450016645e IM-15332-809 431617 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.989
comment: comment:mint
comment: author-confidence:z-score: 3.27946583536927
data source: intact
participant: rpab2_yeast
participant: Protein uniprotkb P10964 identity 1529029542212

ExperimentalForm 5a582abe-d8f6-46f1-acb6-7b2bddceb5c5
type: ExperimentalForm
experimental feature: ModificationFeature 9d9d2023-a9b9-42cc-be2a-eade795183f0 432456
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref go GO 0035101
type: RelationshipXref
id: GO:0035101
db: gene ontology

UnificationXref mint MINT-2207222
type: UnificationXref
id: MINT-2207222
db: mint

ExperimentalForm a644cc08-cdda-4d8d-a2b4-0654818145d4
type: ExperimentalForm
experimental feature: ModificationFeature 5695933e-97b6-4532-a096-afaab3bee6a7 431420
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rfa3_yeast
type: Protein
evidence: Evidence 269c5ee6-7cde-45d8-9b1b-865093c6fda8 p 430854
entity reference: P26755
name: Replication factor A protein 3
comment: psi-mi participant
data source: intact

RelationshipXref sgd S000003684
type: RelationshipXref
id: S000003684
db: sgd

fbrl_yeast
type: Protein
evidence: Evidence dc63d07b-1b86-46a8-b001-a59f65c5ea41 p 430416
entity reference: P15646
name: rRNA 2'-O-methyltransferase fibrillarin
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 5FGA
type: RelationshipXref
id: 5FGA
db: protein data bank

RelationshipXref rcsb pdb 5FGG
type: RelationshipXref
id: 5FGG
db: protein data bank

UnificationXref mint MINT-2196546
type: UnificationXref
id: MINT-2196546
db: mint

RelationshipXref interpro IPR011400
type: RelationshipXref
id: IPR011400
db: interpro

rpc6_yeast
type: Protein
evidence: Evidence fc70255d-47f3-4c2a-a6ea-7d8712269cf7 p 431558
entity reference: P32910
name: DNA-directed RNA polymerase III subunit RPC6
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7534115 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7534115
db: intact

RelationshipXref imex IM-15332-10859 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-10859
db: imex

Evidence 75405179-3618-4536-9481-e2b0b726acec IM-15332-10451 433213 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref imex IM-15332-12884 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12884
db: imex

rpb10-rpb5-1
type: MolecularInteraction
xref: RelationshipXref intact EBI-7525592 identity
xref: RelationshipXref imex IM-15332-8418 imex-primary
xref: UnificationXref mint MINT-2202885
evidence: Evidence d2539c4a-a5c0-4a37-aa76-a6514639de24 IM-15332-8418 432085 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:z-score: 8.29635404112559
comment: author-confidence:reliability score: 0.968
data source: intact
participant: rpab1_yeast
participant: rpab5_yeast

UnificationXref mint MINT-2195195
type: UnificationXref
id: MINT-2195195
db: mint

ExperimentalForm 0d0a7871-f446-402c-8a0c-5d0a42c1474c
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref imex IM-15332-8011 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-8011
db: imex

RelationshipXref intact EBI-7531304 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7531304
db: intact

ExperimentalForm 0013fae7-8c2f-4ede-8a92-06111dbce645
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpc6_yeast
type: Protein
evidence: Evidence 7fe1d5c9-2b6f-4f66-8c2c-ddbf06c85ce6 p 431534
entity reference: P32910
name: DNA-directed RNA polymerase III subunit RPC6
comment: psi-mi participant
data source: intact

ExperimentalForm 7269e2e7-9a4f-4a93-b620-731b868be7b5
type: ExperimentalForm
experimental feature: ModificationFeature 6e962eff-f518-4590-af1b-34985bc9cecd 433596
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpc1_yeast
type: Protein
evidence: Evidence 768f4128-601e-40f8-b052-27fc0daf3332 p 432628
entity reference: rpc1_yeast
name: DNA-directed RNA polymerase III subunit RPC1
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2207204
type: UnificationXref
id: MINT-2207204
db: mint

Evidence 2a98f7eb-164e-4178-9e37-c93e2913073c IM-15332-2370 433745 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref imex IM-15332-5983 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5983
db: imex

RelationshipXref intact EBI-7524435 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7524435
db: intact

RelationshipXref mint Q06103
type: RelationshipXref
id: Q06103
db: mint

rpc6_yeast
type: Protein
evidence: Evidence 1c8bbc61-c0b3-44b8-b355-f19b1b46000d p 431532
entity reference: P32910
name: DNA-directed RNA polymerase III subunit RPC6
comment: psi-mi participant
data source: intact

RelationshipXref refseq NP 014286 1
type: RelationshipXref
id: NP_014286.1
db: refseq

UnificationXref mint MINT-2196528
type: UnificationXref
id: MINT-2196528
db: mint

rpc6_yeast
type: Protein
evidence: Evidence cdfb5dc8-d9e9-4386-b67b-c1bd97fc0063 p 431524
entity reference: P32910
name: DNA-directed RNA polymerase III subunit RPC6
comment: psi-mi participant
data source: intact

ExperimentalForm adf1d5b4-49ed-4d9f-9e78-449df2e5555d
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm dbef0414-35fd-4100-b68e-5e6da5696e1e
type: ExperimentalForm
experimental feature: ModificationFeature 3566f723-5ecf-4b05-8985-79cbe9f42ad3 432579
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref interpro IPR035144
type: RelationshipXref
id: IPR035144
db: interpro

RelationshipXref reactome R-SCE-349425
type: RelationshipXref
id: R-SCE-349425
db: reactome

ret2-cop1-7
type: MolecularInteraction
xref: UnificationXref mint MINT-2196510
xref: RelationshipXref intact EBI-7516556 identity
xref: RelationshipXref imex IM-15332-10844 imex-primary
evidence: Evidence b6f238e3-fc43-47ec-87c1-2b2020117bb3 IM-15332-10844 430669 430156
interaction type: physical association
comment: comment:homomint
comment: comment:mint
comment: author-confidence:z-score: 4.45403908113661
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P43621 identity 1529029541738
participant: Protein uniprotkb P53622 identity 1529029541739

rpa1_yeast
type: Protein
evidence: Evidence c01f592c-576e-4693-a830-c66b0714b9a4 p 431790
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

rpa1_yeast
type: Protein
evidence: Evidence bcab7258-5eaf-423d-920a-405d16a5e95d p 431787
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

rpa1_yeast
type: Protein
evidence: Evidence 79b99465-b315-4d2d-b533-0d9e555c4357 p 431782
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2195177
type: UnificationXref
id: MINT-2195177
db: mint

rpa1_yeast
type: Protein
evidence: Evidence f1fbdc89-b56e-4c2e-98aa-67c80b813441 p 431778
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

rpa1_yeast
type: Protein
evidence: Evidence 9f2d9faa-efcd-4be0-96ee-f49b4fd8a705 p 431774
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7542778 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7542778
db: intact

RelationshipXref intact EBI-7515486 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7515486
db: intact

rpc6_yeast
type: Protein
evidence: Evidence efba3576-4ce8-48b0-914c-9a66f8de8fc8 p 431512
entity reference: P32910
name: DNA-directed RNA polymerase III subunit RPC6
comment: psi-mi participant
data source: intact

rpc6_yeast
type: Protein
evidence: Evidence f1b55c8d-8fbf-42ef-875e-9e84c8b6979d p 431508
entity reference: P32910
name: DNA-directed RNA polymerase III subunit RPC6
comment: psi-mi participant
data source: intact

Evidence 537fdd9d-32c0-48a3-8769-d19c70a56986 IM-15332-1210 431181 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref mint MINT-2200994
type: UnificationXref
id: MINT-2200994
db: mint

ExperimentalForm 611b62ec-0c04-40ea-971a-0fe788ac44d5
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

bud2_yeast
type: ProteinReference
sequence: MSSNNEPAQSRTSYFKLNEFLSNVKHYKNTFKGEIQWCNNLSLNDWKTHYLQITSTGALTHSIDELTADSTNIQPIIKHLQQCRIEIIKDKHSSFKDINANCNFIIQVNTSGKDNKVYLRVKSWSDFKKLLTCLIWWSSMKTNGIFNKFQVSRPLEFKSKKMAKPESLLVYKLNVFGPIVKNIVLPPATNILESPDIINNDDNSVGWFSAMGVLKSNGMLDLLLQSDGSLIYSLNISQLLRSEIRILDSSVLQSENSLFLGELPLLRSQLGLEKFRIENIASAATNSSDISQEIIVEFPLRIDLEDCFIALQSFARSEYLSITGSDKSNDMKISNSFKISILEANFQSINLNDKNNTPWSIFTDITAWGHTWARTSMVSNSSNPFWREEFQFNELLRLTNSYLEIKQLFHDLNNKKRLRLIGKIKITQEIINDTRYNKETRLPIMDVDNKNFQIGTICIKISSNLNFILPSTNFVKLEKLLMNANLSMVSNLIYKSSSSMENDNKLTQTSIIFLDIFQSLSRIEEWFHVLIDKELAKIDGTVSRINQKNLDSKHVFNSLFRGNSILTKSIEQYFFRVGNEYLSKALSAILKEIIESNKSCELDPARVKEKDEVKKRKIIADNYKRLYSWVTKIWKRLYATSNDLPIEIRNVLKIFRQKLEIICIDDTLQIILNGISGLLFLRFFCPVILNPKLFKYVSQNLNETARRNLTLISKVLLNLSTLTQFANKEPWLMKMNNFIDKRHNDLLDYIDKMTQKKLDFNSKILNLSSTISRPKLAIEQTMLDDLPQIPYLLDKNLRETEFVNLIVNFSQEDMTKMEKYNHMDNGGKGELIEEEGLLSGSSLNLSVDKKDLDSPIEVKPEIGELEFEKITENNTEIFGDDLMNLLKSDDVGSRSRDLDNGANSGIKFNSIIPKAEEEKHAMKELEQESCLLYNRINHIRKRLSGYECASSTLFEDKKYSISLSHKIFYEEIKEGKEIVLKLLNKPTNENSSARLQKFFTKGVSSKSNNTVGDSYCKFLTIDVSDENPKSSNKTSVHGTSSENGAKDDYLTLPNSQGKGNLGNRFSPTKLSRIMRKPPNADVPKEQNSRKLTRWFKKKKETGGS
xref: RelationshipXref interpro IPR000008
xref: RelationshipXref go GO 0000131
xref: RelationshipXref mint P33314
xref: RelationshipXref dip DIP-2689N
xref: RelationshipXref go GO 0005935
xref: RelationshipXref go GO 0030447
xref: RelationshipXref go GO 0007165
xref: RelationshipXref go GO 0007163
xref: RelationshipXref uniprotkb D6VXJ6 secondary-ac
xref: RelationshipXref reactome R-SCE-5658442
xref: RelationshipXref go GO 0005096
xref: RelationshipXref reactome R-SCE-5218921
xref: RelationshipXref go GO 0031578
xref: RelationshipXref go GO 0031235
xref: RelationshipXref refseq NP 012831 1
xref: RelationshipXref go GO 0007121
xref: RelationshipXref go GO 0007120
xref: RelationshipXref reactome R-SCE-8849471
xref: RelationshipXref interpro IPR023152
xref: RelationshipXref interpro IPR008936
xref: UnificationXref uniprot knowledgebase P33314
xref: RelationshipXref go GO 0046580
xref: RelationshipXref sgd S000001575
xref: RelationshipXref interpro IPR001936
xref: RelationshipXref interpro IPR035892
xref: RelationshipXref go GO 0036267
xref: RelationshipXref intact EBI-3835 identity
organism: http://identifiers.org/taxonomy/559292
name: YKL092C
name: Bud site selection protein 2
name: BUD2
name: ERC25
name: YKL424
name: Inhibitory regulator protein BUD2/CLA2
name: CLA2

rpa1_yeast
type: Protein
evidence: Evidence 07eb4837-1713-43e4-b792-864a25e44856 p 431771
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

rpa1_yeast
type: Protein
evidence: Evidence e94234c6-b34a-47b4-ae27-c500b3687996 p 431767
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 5FJW
type: RelationshipXref
id: 5FJW
db: protein data bank

rpa1_yeast
type: Protein
evidence: Evidence 65eb7dec-3223-4962-ba1f-313d13f8c66f p 431763
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

RelationshipXref interpro IPR005576
type: RelationshipXref
id: IPR005576
db: interpro

RelationshipXref rcsb pdb 5FJZ
type: RelationshipXref
id: 5FJZ
db: protein data bank

RelationshipXref interpro IPR005574
type: RelationshipXref
id: IPR005574
db: interpro

ExperimentalForm 9edf30b9-e942-473a-80db-9505d90b441a
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref interpro IPR005571
type: RelationshipXref
id: IPR005571
db: interpro

ExperimentalForm 9ac58a2d-a208-4dc8-badb-f0843806ed39
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7543016 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7543016
db: intact

tho2-mft1-1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-12872 imex-primary
xref: UnificationXref mint MINT-2199050
xref: RelationshipXref intact EBI-7519647 identity
evidence: Evidence 7af998f2-12aa-4a20-890d-4f59aae14b8c IM-15332-12872 431233 430156
interaction type: physical association
comment: comment:mint
comment: author-confidence:reliability score: 0.99
comment: author-confidence:z-score: 8.03400763613764
data source: intact
participant: Protein uniprotkb P53552 identity 1529029542021
participant: Protein uniprotkb P33441 identity 1529029542020

RelationshipXref imex IM-15332-2748 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-2748
db: imex

med9_yeast
type: ProteinReference
sequence: MNLQNNVLNQIHQILLPTNPTLDKPNAEATKEEFSSAENRDEKDYLTNQQPKNLSTPSTSSNGEFIPHIFYSLHQIRKDPNNLSNQLETLTGSIRHRLKLCKSLISENEDTKDLLSKSPSEWQDIIHQREQELQIKRDVLDDLYRKLQR
xref: RelationshipXref go GO 0070847
xref: RelationshipXref go GO 0005634
xref: RelationshipXref uniprotkb D6W1I5 secondary-ac
xref: RelationshipXref interpro IPR011425
xref: RelationshipXref intact EBI-5174 identity
xref: RelationshipXref go GO 0000122
xref: RelationshipXref go GO 0005198
xref: RelationshipXref go GO 0016592
xref: RelationshipXref refseq NP 014407 3
xref: RelationshipXref mint P33308
xref: RelationshipXref go GO 0001128
xref: RelationshipXref go GO 0045944
xref: RelationshipXref rcsb pdb 5SVA
xref: RelationshipXref go GO 0005829
xref: RelationshipXref sgd S000005293
xref: UnificationXref uniprot knowledgebase P33308
xref: RelationshipXref dip DIP-1276N
organism: http://identifiers.org/taxonomy/559292
name: Mediator of RNA polymerase II transcription subunit 9
name: N2046
name: Chromosome segregation protein 2
name: CSE2
name: YNR010W
name: MED9
name: Mediator complex subunit 9

RelationshipXref uniprotkb Q12073 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: Q12073
db: uniprot knowledgebase

RelationshipXref intact EBI-8541 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-8541
db: intact

RelationshipXref refseq NP 015186 1
type: RelationshipXref
id: NP_015186.1
db: refseq

rpa1_yeast
type: Protein
evidence: Evidence 0caf3cbd-6a3c-4dda-bceb-9f28f26362b1 p 431747
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2195159
type: UnificationXref
id: MINT-2195159
db: mint

rpa1_yeast
type: Protein
evidence: Evidence 94e98907-fe03-4a2a-88c4-d396645f327f p 431742
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

rpa1_yeast
type: Protein
evidence: Evidence ea097f99-3a22-40b6-a7fe-f356d8d46769 p 431739
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

ExperimentalForm f8df36ad-9dc9-4114-80f0-8a8de93baec6
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpa1_yeast
type: Protein
evidence: Evidence 2860a1a0-70af-49fd-9cc8-e928121f7a62 p 431734
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

ExperimentalForm 946552b7-6157-476c-96f0-5e0a5ec2f1d4
type: ExperimentalForm
experimental feature: ModificationFeature 019b64c1-e623-4f37-8a22-1079a3d95490 433599
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

tfs2_yeast
type: Protein
evidence: Evidence 12f84fcb-2566-4809-83f3-26a303334e63 p 432322
entity reference: P07273
name: Transcription elongation factor S-II
comment: psi-mi participant
data source: intact

Evidence ec59ddb6-9d5b-450a-904b-e7cc2b09312a IM-15332-10862 433417 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref imex IM-15332-5990 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5990
db: imex

ExperimentalForm ca06bb54-2824-4296-a93b-88282a45e271
type: ExperimentalForm
experimental feature: ModificationFeature b96eab0e-cbcc-4ca1-9189-284af0e0067b 432383
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

Evidence 22dc8d2d-5b5d-403e-8723-8ff7d1299e10 IM-15332-4403 433205 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref intact EBI-7524689 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7524689
db: intact

RelationshipXref intact EBI-7541645 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7541645
db: intact

rpa1_yeast
type: Protein
evidence: Evidence 0d76b41a-34ba-48af-9adf-2a5f529d68d3 p 431723
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 4U4U
type: RelationshipXref
id: 4U4U
db: protein data bank

rpa1_yeast
type: Protein
evidence: Evidence 92e16809-e8dc-408b-a5d3-f7bfe2851f75 p 431715
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

rfa2-dna2-1
type: MolecularInteraction
xref: UnificationXref mint MINT-2196996
xref: RelationshipXref imex IM-15332-7190 imex-primary
xref: RelationshipXref intact EBI-7517070 identity
evidence: Evidence 9353f6bc-2bf5-4f50-b8f4-a81f17e37ead IM-15332-7190 430777 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.771
comment: comment:mint
comment: author-confidence:z-score: 2.25083461685524
data source: intact
participant: Protein uniprotkb P26754 identity 1529029541792
participant: dna2_yeast

ExperimentalForm d30e6ae4-c5ae-4b1e-9fa4-53fe10e591c9
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rpc40-rpa49-4
type: MolecularInteraction
xref: RelationshipXref intact EBI-7536462 identity
xref: RelationshipXref imex IM-15332-4403 imex-primary
xref: UnificationXref mint MINT-2207978
evidence: Evidence 22dc8d2d-5b5d-403e-8723-8ff7d1299e10 IM-15332-4403 433205 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.983
comment: comment:mint
comment: author-confidence:z-score: 0.0944617875102253
data source: intact
participant: rpa49_yeast
participant: Protein uniprotkb P07703 identity 1529029543007

RelationshipXref intact EBI-7536493 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7536493
db: intact

rpa1_yeast
type: Protein
evidence: Evidence 655d5382-489b-4358-ace6-0eda8102ba05 p 431707
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

rpa1_yeast
type: Protein
evidence: Evidence 86e7fb30-20d5-4ce5-b3a8-b0ed811cce8f p 431702
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

rpa1_yeast
type: Protein
evidence: Evidence 6cc66260-b5f3-4103-b335-b4ac1cabe12a p 431699
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-9615 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-9615
db: imex

RelationshipXref sgd S000003612
type: RelationshipXref
id: S000003612
db: sgd

ExperimentalForm 3922a4d4-e861-4f8f-a8b9-d2666e1fdd44
type: ExperimentalForm
experimental feature: ModificationFeature dc9e1d0a-5525-46dd-abdb-d87603bdfbb8 432243
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 57bb6aa8-eb24-4c36-bcc0-5daf2c36b527
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7527098 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7527098
db: intact

rpa1_yeast
type: Protein
evidence: Evidence 9457c7f8-23fb-49cc-93a2-ad748fb4aa25 p 431690
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

ExperimentalForm 5ccc6c0d-14eb-4eca-9005-8b16e0b68e13
type: ExperimentalForm
experimental feature: ModificationFeature 2fdc49ec-f23b-417c-b017-8c91ecc553dc 430496
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpb3_yeast
type: Protein
evidence: Evidence 1051b2fe-586d-48a4-8041-58c093617c2d p 432314
entity reference: P16370
name: DNA-directed RNA polymerase II subunit RPB3
comment: psi-mi participant
data source: intact

rpa1_yeast
type: Protein
evidence: Evidence 4436968e-3db3-47f4-8662-13649a2e40cf p 431682
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

rpa1_yeast
type: Protein
evidence: Evidence 28f63d04-398e-4b6e-bdd4-23e4642ae0e6 p 431679
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

rpa1_yeast
type: Protein
evidence: Evidence 495b33c1-4cc6-4751-8689-45abd1dd234d p 431674
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2195123
type: UnificationXref
id: MINT-2195123
db: mint

Evidence 2497fd58-e2d4-479b-a439-b962a9b49acb IM-15332-10423 430393 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpb3-spt5
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-1584 imex-primary
xref: RelationshipXref intact EBI-7527875 identity
xref: UnificationXref mint MINT-2203911
evidence: Evidence d3bb7a24-75a5-40d4-b331-db2fcea2e277 IM-15332-1584 432313 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.753
comment: comment:homomint
comment: author-confidence:z-score: -0.0739082006331827
comment: comment:mint
data source: intact
participant: Protein uniprotkb P27692 identity 1529029542561
participant: rpb3_yeast

RelationshipXref imex IM-15332-2372 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-2372
db: imex

RelationshipXref go GO 0043709
type: RelationshipXref
id: GO:0043709
db: gene ontology

RelationshipXref go GO 0008565
type: RelationshipXref
id: GO:0008565
db: gene ontology

RelationshipXref sgd S000002255
type: RelationshipXref
id: S000002255
db: sgd

RelationshipXref imex IM-15332-3176 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-3176
db: imex

rpa1_yeast
type: Protein
evidence: Evidence 433d6e1f-a2a3-4aa1-a483-1c935aa6325e p 431670
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

rpa1_yeast
type: Protein
evidence: Evidence 02d782f7-992d-4ae8-84de-9ef4af5a7afd p 431666
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

RelationshipXref intact EBI-7530123 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7530123
db: intact

rpa1_yeast
type: Protein
evidence: Evidence 7069f3e1-a302-4608-89fc-1688920b4763 p 431655
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-5580 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5580
db: imex

Evidence 35f81371-1e9f-4c0e-b83a-e85cb9084d5e IM-15332-6790 433529 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm 9e2c48a9-dbee-4a3f-89e6-37055caf54d3
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7526320 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7526320
db: intact

RelationshipXref rcsb pdb 3JCP
type: RelationshipXref
id: 3JCP
db: protein data bank

RelationshipXref imex IM-15332-9625 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-9625
db: imex

rpa1_yeast
type: Protein
evidence: Evidence 4dbc34d9-a42b-4124-b81f-209b697bfaa3 p 431646
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

rpa1_yeast
type: Protein
evidence: Evidence cc386a97-b6b1-4a47-955d-908e2477d161 p 431642
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

rpa1_yeast
type: Protein
evidence: Evidence 123b095b-0b4b-402e-b561-145f8facf520 p 431639
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

rpa1_yeast
type: Protein
evidence: Evidence 2f6ae333-2a59-4ad0-a6dd-86477b182e06 p 431635
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

Evidence d80b46f8-9c26-4999-8590-02f9e91d749e IM-15332-3580 430761 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref imex IM-15332-2350 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-2350
db: imex

rpb10-rpb2-1
type: MolecularInteraction
xref: RelationshipXref intact EBI-7524420 identity
xref: RelationshipXref imex IM-15332-6779 imex-primary
xref: UnificationXref mint MINT-2202219
evidence: Evidence 3cb2503f-3f6e-4cfb-8658-5419e63dda2e IM-15332-6779 431937 430156
interaction type: physical association
comment: author-confidence:reliability score: 0.989
comment: comment:mint
comment: author-confidence:z-score: 3.14743439709949
data source: intact
participant: Protein uniprotkb P08518 identity 1529029542373
participant: rpab5_yeast

rpab3_yeast
type: Protein
evidence: Evidence fa4590da-2637-406a-bd8d-f107c99a4596 p 432343
entity reference: P20436
name: DNA-directed RNA polymerases I, II, and III subunit RPABC3
comment: psi-mi participant
data source: intact

rpb9-dst1-1
type: MolecularInteraction
xref: UnificationXref mint MINT-2205033
xref: RelationshipXref imex IM-15332-812 imex-primary
xref: RelationshipXref intact EBI-7531371 identity
evidence: Evidence 8490ddb9-2e3c-4926-84e5-164a0f383528 IM-15332-812 432553 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.81
comment: comment:mint
comment: author-confidence:z-score: 0.0300609204351594
data source: intact
participant: Protein uniprotkb P27999 identity 1529029542681
participant: Protein uniprotkb P07273 identity 1529029542680

ret2-cop1-5
type: MolecularInteraction
xref: UnificationXref mint MINT-2196222
xref: RelationshipXref imex IM-15332-12473 imex-primary
xref: RelationshipXref intact EBI-7516118 identity
evidence: Evidence a3c2cfdb-c904-481f-89de-13322095fa3c IM-15332-12473 430605 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 4.47034854410636
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: copa_yeast
participant: Protein uniprotkb P43621 identity 1529029541707

RelationshipXref interpro IPR004161
type: RelationshipXref
id: IPR004161
db: interpro

RelationshipXref go GO 0008541
type: RelationshipXref
id: GO:0008541
db: gene ontology

RelationshipXref go GO 0008540
type: RelationshipXref
id: GO:0008540
db: gene ontology

rpa1_yeast
type: Protein
evidence: Evidence c31130cc-3949-4fea-8c8c-68e2f0d1617f p 431630
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

rpa1_yeast
type: Protein
evidence: Evidence 1992ba4b-f43f-4666-8bce-7728e6e99fd9 p 431626
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

ExperimentalForm e7b27e70-d19d-4c9e-acc8-e207f5605278
type: ExperimentalForm
experimental feature: ModificationFeature 4356771a-d405-43c2-a96a-3ad3c02e5d30 430932
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

ExperimentalForm 29df96d0-b92a-464d-9bcf-5e2cb6e30eaa
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref go GO 2001159
type: RelationshipXref
id: GO:2001159
db: gene ontology

ExperimentalForm 29e7f65d-f3cd-4442-a868-4444ffcfd66c
type: ExperimentalForm
experimental feature: ModificationFeature 0799bbb1-ccef-4cf3-94a7-b86a1a0d6ef3 432655
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpb8-yp225-8
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-400 imex-primary
xref: RelationshipXref intact EBI-7529075 identity
xref: UnificationXref mint MINT-2204147
evidence: Evidence 89ba9cc1-1dde-4830-af52-4118723e55ed IM-15332-400 432365 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.989
comment: author-confidence:z-score: 9.5950323287407
comment: comment:mint
data source: intact
participant: Protein uniprotkb Q08971 identity 1529029542587
participant: rpab3_yeast

RelationshipXref interpro IPR036575
type: RelationshipXref
id: IPR036575
db: interpro

ExperimentalForm d1c6eeb3-53fe-4e22-b925-d407665690e6
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm e06d9b41-986c-4fe6-8923-4f15e102065a
type: ExperimentalForm
experimental feature: ModificationFeature fd37b0ba-f380-43fe-a0d6-a3f1a2384344 433147
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

top2_yeast
type: ProteinReference
sequence: MSTEPVSASDKYQKISQLEHILKRPDTYIGSVETQEQLQWIYDEETDCMIEKNVTIVPGLFKIFDEILVNAADNKVRDPSMKRIDVNIHAEEHTIEVKNDGKGIPIEIHNKENIYIPEMIFGHLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTEFILETADLNVGQKYVQKWENNMSICHPPKITSYKKGPSYTKVTFKPDLTRFGMKELDNDILGVMRRRVYDINGSVRDINVYLNGKSLKIRNFKNYVELYLKSLEKKRQLDNGEDGAAKSDIPTILYERINNRWEVAFAVSDISFQQISFVNSIATTMGGTHVNYITDQIVKKISEILKKKKKKSVKSFQIKNNMFIFINCLIENPAFTSQTKEQLTTRVKDFGSRCEIPLEYINKIMKTDLATRMFEIADANEENALKKSDGTRKSRITNYPKLEDANKAGTKEGYKCTLVLTEGDSALSLAVAGLAVVGRDYYGCYPLRGKMLNVREASADQILKNAEIQAIKKIMGLQHRKKYEDTKSLRYGHLMIMTDQDHDGSHIKGLIINFLESSFPGLLDIQGFLLEFITPIIKVSITKPTKNTIAFYNMPDYEKWREEESHKFTWKQKYYKGLGTSLAQEVREYFSNLDRHLKIFHSLQGNDKDYIDLAFSKKKADDRKEWLRQYEPGTVLDPTLKEIPISDFINKELILFSLADNIRSIPNVLDGFKPGQRKVLYGCFKKNLKSELKVAQLAPYVSECTAYHHGEQSLAQTIIGLAQNFVGSNNIYLLLPNGAFGTRATGGKDAAAARYIYTELNKLTRKIFHPADDPLYKYIQEDEKTVEPEWYLPILPMILVNGAEGIGTGWSTYIPPFNPLEIIKNIRHLMNDEELEQMHPWFRGWTGTIEEIEPLRYRMYGRIEQIGDNVLEITELPARTWTSTIKEYLLLGLSGNDKIKPWIKDMEEQHDDNIKFIITLSPEEMAKTRKIGFYERFKLISPISLMNMVAFDPHGKIKKYNSVNEILSEFYYVRLEYYQKRKDHMSERLQWEVEKYSFQVKFIKMIIEKELTVTNKPRNAIIQELENLGFPRFNKEGKPYYGSPNDEIAEQINDVKGATSDEEDEESSHEDTENVINGPEELYGTYEYLLGMRIWSLTKERYQKLLKQKQEKETELENLLKLSAKDIWNTDLKAFEVGYQEFLQRDAEARGGNVPNKGSKTKGKGKRKLVDDEDYDPSKKNKKSTARKGKKIKLEDKNFERILLEQKLVTKSKAPTKIKKEKTPSVSETKTEEEENAPSSTSSSSIFDIKKEDKDEGELSKISNKFKKISTIFDKMGSTSATSKENTPEQDDVATKKNQTTAKKTAVKPKLAKKPVRKQQKVVELSGESDLEILDSYTDREDSNKDEDDAIPQRSRRQRSSRAASVPKKSYVETLELSDDSFIEDDEEENQGSDVSFNEED
xref: RelationshipXref intact EBI-19352 identity
xref: RelationshipXref go GO 0042802
xref: RelationshipXref go GO 0005524
xref: RelationshipXref interpro IPR018522
xref: RelationshipXref refseq NP 014311 3
xref: RelationshipXref interpro IPR031660
xref: RelationshipXref sgd S000005032
xref: RelationshipXref rcsb pdb 1BJT
xref: RelationshipXref go GO 0007131
xref: RelationshipXref go GO 0097047
xref: RelationshipXref go GO 0097046
xref: RelationshipXref interpro IPR006171
xref: RelationshipXref go GO 0000712
xref: RelationshipXref go GO 0000819
xref: RelationshipXref go GO 0006271
xref: RelationshipXref uniprotkb D6W191 secondary-ac
xref: RelationshipXref interpro IPR003594
xref: RelationshipXref interpro IPR013506
xref: RelationshipXref go GO 0046872
xref: RelationshipXref go GO 0006265
xref: RelationshipXref go GO 0044774
xref: RelationshipXref go GO 0006333
xref: RelationshipXref rcsb pdb 2RGR
xref: RelationshipXref go GO 0000019
xref: RelationshipXref interpro IPR034157
xref: RelationshipXref dip DIP-2300N
xref: RelationshipXref go GO 0000795
xref: RelationshipXref rcsb pdb 4GFH
xref: RelationshipXref interpro IPR013760
xref: RelationshipXref mint P06786
xref: RelationshipXref interpro IPR036890
xref: RelationshipXref rcsb pdb 1PVG
xref: RelationshipXref interpro IPR014721
xref: RelationshipXref go GO 0003677
xref: RelationshipXref rcsb pdb 3L4K
xref: RelationshipXref go GO 0005634
xref: RelationshipXref interpro IPR013759
xref: RelationshipXref reactome R-SCE-4615885
xref: RelationshipXref interpro IPR001241
xref: RelationshipXref interpro IPR020568
xref: RelationshipXref rcsb pdb 1QZR
xref: RelationshipXref rcsb pdb 1BGW
xref: UnificationXref uniprot knowledgebase P06786
xref: RelationshipXref rcsb pdb 3L4J
xref: RelationshipXref go GO 0003918
xref: RelationshipXref go GO 0031055
xref: RelationshipXref interpro IPR002205
organism: http://identifiers.org/taxonomy/559292
name: DNA topoisomerase II
name: TOP2
name: TOR3
name: N2244
name: DNA topoisomerase 2
name: YNL088W

ExperimentalForm 983a5a41-b7c6-4569-a598-ec6f0a4ed052
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref reactome R-SCE-72731
type: RelationshipXref
id: R-SCE-72731
db: reactome

rpa1_yeast
type: Protein
evidence: Evidence 7e65d521-ee21-4dc1-92fc-0f65c411aeef p 431611
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

UnificationXref uniprot knowledgebase P53633
type: UnificationXref
id: P53633
db: uniprot knowledgebase

rpa1_yeast
type: Protein
evidence: Evidence d6472eb5-040d-42b9-8088-ef6f8e69fe19 p 431606
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

rpa1_yeast
type: Protein
evidence: Evidence bc720fa3-d510-465b-a7a9-af03bcae8d8b p 431603
entity reference: P10964
name: DNA-directed RNA polymerase I subunit RPA190
comment: psi-mi participant
data source: intact

rpab3_yeast
type: Protein
evidence: Evidence d917904a-235e-4d26-8f29-758d68748045 p 432358
entity reference: P20436
name: DNA-directed RNA polymerases I, II, and III subunit RPABC3
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-5168 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-5168
db: imex

Evidence bf0d9704-2abd-4bcd-860d-f74d1960ddb4 IM-15332-6773 430933 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpc19-rpc53-2
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-8423 imex-primary
xref: UnificationXref mint MINT-2206105
xref: RelationshipXref intact EBI-7532952 identity
evidence: Evidence d9401bde-55ab-4348-ac72-3dccca1cdeae IM-15332-8423 432789 430156
interaction type: physical association
comment: author-confidence:z-score: 9.55505257685535
comment: comment:homomint
comment: author-confidence:reliability score: 0.963
comment: comment:mint
data source: intact
participant: Protein uniprotkb P25441 identity 1529029542798
participant: Protein uniprotkb P28000 identity 1529029542799

rpb9-rpb2-10
type: MolecularInteraction
xref: UnificationXref mint MINT-2204873
xref: RelationshipXref intact EBI-7531192 identity
xref: RelationshipXref imex IM-15332-10445 imex-primary
evidence: Evidence 5bcec531-7a9d-42a9-9fb0-76d260cf1618 IM-15332-10445 432521 430156
interaction type: physical association
comment: author-confidence:z-score: 3.33921571412567
comment: author-confidence:reliability score: 0.989
comment: comment:mint
data source: intact
participant: Protein uniprotkb P27999 identity 1529029542665
participant: Protein uniprotkb P08518 identity 1529029542664

RelationshipXref rcsb pdb 4QV5
type: RelationshipXref
id: 4QV5
db: protein data bank

RelationshipXref imex IM-15332-1600 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1600
db: imex

UnificationXref mint MINT-2209994
type: UnificationXref
id: MINT-2209994
db: mint

RelationshipXref rcsb pdb 4LTC
type: RelationshipXref
id: 4LTC
db: protein data bank

UnificationXref uniprot knowledgebase P53622
type: UnificationXref
id: P53622
db: uniprot knowledgebase

ExperimentalForm 26911261-e010-4bee-b823-9fcb5291c24f
type: ExperimentalForm
experimental feature: ModificationFeature 66955ec6-86d4-4e61-872c-c57c02ed7734 433136
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref rcsb pdb 3HYE
type: RelationshipXref
id: 3HYE
db: protein data bank

Evidence 8ff32777-53e2-46f2-a81e-0c3c502f4d0d IM-15332-11255 432625 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref imex IM-15332-12050 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12050
db: imex

rpab1_yeast
type: Protein
evidence: Evidence 42298247-0d25-4f59-b839-b7d96b3c18b8 p 431752
entity reference: rpab1_yeast
name: DNA-directed RNA polymerases I, II, and III subunit RPABC1
comment: psi-mi participant
data source: intact

RelationshipXref uniprotkb D6W0E1 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6W0E1
db: uniprot knowledgebase

rpab3_yeast
type: Protein
evidence: Evidence 06c47d8a-3f34-4aba-a26c-43f00100782e p 432375
entity reference: P20436
name: DNA-directed RNA polymerases I, II, and III subunit RPABC3
comment: psi-mi participant
data source: intact

RelationshipXref go GO 0000993
type: RelationshipXref
id: GO:0000993
db: gene ontology

RelationshipXref go GO 0000991
type: RelationshipXref
id: GO:0000991
db: gene ontology

RelationshipXref go GO 0007165
type: RelationshipXref
id: GO:0007165
db: gene ontology

Evidence ab3ca63c-abf5-4841-97f9-e385509b71cb IM-15332-8023 431797 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref mint MINT-2209976
type: UnificationXref
id: MINT-2209976
db: mint

RelationshipXref reactome R-SCE-72706
type: RelationshipXref
id: R-SCE-72706
db: reactome

spt5_yeast
type: Protein
evidence: Evidence 9f17516e-4990-46e2-a038-7fe80ae0ef89 p 432318
entity reference: P27692
name: Transcription elongation factor SPT5
comment: psi-mi participant
data source: intact

rfc1-rfc4
type: MolecularInteraction
xref: UnificationXref mint MINT-2197466
xref: RelationshipXref imex IM-15332-8801 imex-primary
xref: RelationshipXref intact EBI-7517564 identity
evidence: Evidence 3a06e42f-e8c8-4c6a-9c69-eb77b8dd17bb IM-15332-8801 430881 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 9.6975782775731
comment: author-confidence:reliability score: 0.985
comment: comment:mint
data source: intact
participant: Protein uniprotkb P40339 identity 1529029541845
participant: Protein uniprotkb P38630 identity 1529029541844

RelationshipXref go GO 0000981
type: RelationshipXref
id: GO:0000981
db: gene ontology

rpn12_yeast
type: Protein
evidence: Evidence c3e8ebc8-7652-44e7-b9a5-f04efd5c7e05 p 433750
entity reference: P32496
name: 26S proteasome regulatory subunit RPN12
comment: psi-mi participant
data source: intact

Evidence bba4ffc8-03ae-40cc-8c19-a388150ea834 IM-15332-8011 430685 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref interpro IPR033464
type: RelationshipXref
id: IPR033464
db: interpro

ExperimentalForm 3a378142-9c13-4671-b754-48ec25c8d2bb
type: ExperimentalForm
experimental feature: ModificationFeature 475b592c-e27a-492a-adad-490d4fe5ed59 430476
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-796 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-796
db: imex

RelationshipXref imex IM-15332-396 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-396
db: imex

rpd3-grx5-2
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-4793 imex-primary
xref: RelationshipXref intact EBI-7538201 identity
xref: UnificationXref mint MINT-2208554
evidence: Evidence 3ffa57e0-8317-464b-8e37-73e150dd2ed4 IM-15332-4793 433333 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.593
comment: author-confidence:z-score: 2.01415624951162
comment: comment:mint
data source: intact
participant: Protein uniprotkb Q02784 identity 1529029543071
participant: rpd3_yeast

rpab1_yeast
type: Protein
evidence: Evidence d32f5b54-6a48-446e-9756-2db356ac2c18 p 431712
entity reference: rpab1_yeast
name: DNA-directed RNA polymerases I, II, and III subunit RPABC1
comment: psi-mi participant
data source: intact

RelationshipXref go GO 0000979
type: RelationshipXref
id: GO:0000979
db: gene ontology

RelationshipXref go GO 0000978
type: RelationshipXref
id: GO:0000978
db: gene ontology

RelationshipXref go GO 0000977
type: RelationshipXref
id: GO:0000977
db: gene ontology

RelationshipXref uniprotkb D6VTT4 secondary-ac
type: RelationshipXref
relationship type: MI:0360
id: D6VTT4
db: uniprot knowledgebase

RelationshipXref intact EBI-7534035 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7534035
db: intact

RelationshipXref intact EBI-7535081 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7535081
db: intact

rpn1-rpn12-4
type: MolecularInteraction
xref: UnificationXref mint MINT-2210318
xref: RelationshipXref intact EBI-7542142 identity
xref: RelationshipXref imex IM-15332-1225 imex-primary
evidence: Evidence 8518c233-5db3-476c-bc03-349ee84c04b2 IM-15332-1225 433725 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.983
comment: author-confidence:z-score: 8.08315909020889
comment: comment:mint
data source: intact
participant: Protein uniprotkb P38764 identity 1529029543266
participant: rpn12_yeast

rpn12_yeast
type: Protein
evidence: Evidence 55e7fbee-f27c-4759-bb63-1bf89a2a23eb p 433728
entity reference: P32496
name: 26S proteasome regulatory subunit RPN12
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2209958
type: UnificationXref
id: MINT-2209958
db: mint

Evidence 089a8b17-4c3f-4ec7-adae-d74758f73730 IM-15332-10857 432637 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

tho2-mft1-2
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-1211 imex-primary
xref: RelationshipXref intact EBI-7519948 identity
xref: UnificationXref mint MINT-2199176
evidence: Evidence 3f7c5299-0577-4ba9-849b-1d46c50fd951 IM-15332-1211 431261 430156
interaction type: physical association
comment: comment:mint
comment: author-confidence:reliability score: 0.99
comment: author-confidence:z-score: 7.06693533288425
data source: intact
participant: Protein uniprotkb P53552 identity 1529029542034
participant: Protein uniprotkb P33441 identity 1529029542035

RelationshipXref imex IM-15332-3986 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-3986
db: imex

Evidence b4ca68c2-2cf5-4dba-ae7a-e1385eb7edee IM-15332-9615 432645 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

rpb9_yeast
type: Protein
evidence: Evidence 56fd084b-d394-47bc-840f-3a726dd2ec0e p 432574
entity reference: P27999
name: DNA-directed RNA polymerase II subunit RPB9
comment: psi-mi participant
data source: intact

ExperimentalForm bcab85e6-b444-411f-920f-7da91db73c14
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

ExperimentalForm d599feab-8787-42f6-bb95-3845dd976e3b
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref go GO 0007131
type: RelationshipXref
id: GO:0007131
db: gene ontology

Evidence 58597e25-57f9-45b0-8715-f77ebcece04c IM-15332-7643 432633 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref rcsb pdb 2DZO
type: RelationshipXref
id: 2DZO
db: protein data bank

RelationshipXref rcsb pdb 2DZN
type: RelationshipXref
id: 2DZN
db: protein data bank

UnificationXref mint MINT-2209940
type: UnificationXref
id: MINT-2209940
db: mint

RelationshipXref intact EBI-7525799 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7525799
db: intact

ExperimentalForm 6fd77e51-0f16-496a-bbeb-d8e5e4a8b124
type: ExperimentalForm
experimental feature: ModificationFeature 0a218309-a550-42d5-a71a-2b90aabab452 432812
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpab2_yeast
type: Protein
evidence: Evidence 96498bd9-8e77-49ba-8c25-f0f6185a8ad1 p 431608
entity reference: rpab2_yeast
name: DNA-directed RNA polymerases I, II, and III subunit RPABC2
comment: psi-mi participant
data source: intact

RelationshipXref go GO 0007124
type: RelationshipXref
id: GO:0007124
db: gene ontology

UnificationXref mint MINT-2208590
type: UnificationXref
id: MINT-2208590
db: mint

RelationshipXref go GO 0007121
type: RelationshipXref
id: GO:0007121
db: gene ontology

RelationshipXref go GO 0007120
type: RelationshipXref
id: GO:0007120
db: gene ontology

Evidence a554b735-fa58-4d3b-9186-06ab898405c4 IM-15332-10036 433149 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref intact EBI-15786 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-15786
db: intact

rpab2_yeast
type: Protein
evidence: Evidence 963c3881-8575-4184-aa62-dc368cd3d2e3 p 431620
entity reference: rpab2_yeast
name: DNA-directed RNA polymerases I, II, and III subunit RPABC2
comment: psi-mi participant
data source: intact

RelationshipXref rcsb pdb 3I4M
type: RelationshipXref
id: 3I4M
db: protein data bank

RelationshipXref go GO 0007117
type: RelationshipXref
id: GO:0007117
db: gene ontology

ExperimentalForm e367219e-d0a5-4bea-b6ce-560e623312fe
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref imex IM-15332-3996 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-3996
db: imex

Evidence 057ab0c3-660c-496e-b900-64e6927e47e6 IM-15332-802 430765 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

ExperimentalForm 860dffba-11f3-45d2-bc3c-ef742b210b13
type: ExperimentalForm
experimental feature: ModificationFeature be5acd45-7b98-488d-917d-ca324c011160 433144
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref sgd S000000517
type: RelationshipXref
id: S000000517
db: sgd

ExperimentalForm f5732b51-b20e-475b-8887-6d606d329452
type: ExperimentalForm
experimental feature: ModificationFeature 752652c1-67bc-4b29-9120-331b8ac4be2d 430687
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

UnificationXref mint MINT-2208572
type: UnificationXref
id: MINT-2208572
db: mint

rfa3-rfa2-1
type: MolecularInteraction
xref: UnificationXref mint MINT-2197339
xref: RelationshipXref imex IM-15332-12041 imex-primary
xref: RelationshipXref intact EBI-7517437 identity
evidence: Evidence a9e1002c-3ddf-4921-a4dd-13e8e51622df IM-15332-12041 430853 430156
interaction type: physical association
comment: author-confidence:z-score: 9.40593441035942
comment: author-confidence:reliability score: 0.989
comment: comment:mint
data source: intact
participant: rfa3_yeast
participant: Protein uniprotkb P26754 identity 1529029541831

ExperimentalForm 566cff33-26b3-4360-bb3d-356060db1a74
type: ExperimentalForm
experimental feature: ModificationFeature 91ca478e-231f-4bbf-96c2-ec73559e2f7c 430903
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

UnificationXref mint MINT-2197898
type: UnificationXref
id: MINT-2197898
db: mint

rpn1-rpt6-9
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-4795 imex-primary
xref: UnificationXref mint MINT-2210354
xref: RelationshipXref intact EBI-7542196 identity
evidence: Evidence 1659710d-6d7c-49f2-8289-a68cd7c40ac7 IM-15332-4795 433733 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 9.71807643443817
comment: comment:mint
comment: author-confidence:reliability score: 0.944
data source: intact
participant: Protein uniprotkb Q01939 identity 1529029543271
participant: Protein uniprotkb P38764 identity 1529029543270

RelationshipXref intact EBI-7525393 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7525393
db: intact

rpab1_yeast
type: Protein
evidence: Evidence 163fe2ca-4a70-4b2e-ba9b-86ad108188c9 p 431600
entity reference: rpab1_yeast
name: DNA-directed RNA polymerases I, II, and III subunit RPABC1
comment: psi-mi participant
data source: intact

ExperimentalForm 36713e78-66a8-46a5-b311-c10f97f17b24
type: ExperimentalForm
experimental feature: ModificationFeature ac782c62-6be9-4cbe-a13d-9e18a3a31813 430404
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

prs10_yeast
type: Protein
evidence: Evidence ebdcbb89-cbdb-4f70-a62f-87642a2721e3 p 433788
entity reference: P53549
name: 26S proteasome subunit RPT4
comment: psi-mi participant
data source: intact

prs10_yeast
type: Protein
evidence: Evidence 7b90f15d-4435-455d-80f2-a40f160863cf p 433780
entity reference: P53549
name: 26S proteasome subunit RPT4
comment: psi-mi participant
data source: intact

rpb10-rpo21-5
type: MolecularInteraction
xref: UnificationXref mint MINT-2202795
xref: RelationshipXref imex IM-15332-1955 imex-primary
xref: RelationshipXref intact EBI-7525448 identity
evidence: Evidence aa230fb6-f951-4dbd-bef5-13b67e1195c8 IM-15332-1955 432065 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 2.71047082971376
comment: comment:mint
comment: author-confidence:reliability score: 0.968
data source: intact
participant: Protein uniprotkb P04050 identity 1529029542436
participant: rpab5_yeast

RelationshipXref intact EBI-15949 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-15949
db: intact

RelationshipXref interpro IPR033403
type: RelationshipXref
id: IPR033403
db: interpro

RelationshipXref intact EBI-7531176 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7531176
db: intact

ExperimentalForm 8370422d-2c7d-452a-93b8-23443a354b54
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref mint MINT-2209904
type: UnificationXref
id: MINT-2209904
db: mint

rir1_yeast
type: Protein
evidence: Evidence 93066ef5-22e7-4707-80fc-e0f31f78cba4 p 431371
entity reference: P21524
name: Ribonucleoside-diphosphate reductase large chain 1
comment: psi-mi participant
data source: intact

RelationshipXref sgd S000000537
type: RelationshipXref
id: S000000537
db: sgd

rpb3-rpb4-1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-11639 imex-primary
xref: RelationshipXref intact EBI-7527323 identity
xref: UnificationXref mint MINT-2203749
evidence: Evidence c7522de9-03f7-46b6-8c83-57f0dca0eacf IM-15332-11639 432277 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.989
comment: author-confidence:z-score: 8.32729929023001
comment: comment:mint
data source: intact
participant: Protein uniprotkb P16370 identity 1529029542543
participant: Protein uniprotkb P20433 identity 1529029542542

UnificationXref mint MINT-2197880
type: UnificationXref
id: MINT-2197880
db: mint

rpd3-grx5-1
type: MolecularInteraction
xref: UnificationXref mint MINT-2208536
xref: RelationshipXref imex IM-15332-10038 imex-primary
xref: RelationshipXref intact EBI-7538185 identity
evidence: Evidence 9ecd5fcd-66b9-4b5b-8b2a-f13bd52f9799 IM-15332-10038 433329 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.593
comment: comment:mint
comment: author-confidence:z-score: 3.44961875278743
data source: intact
participant: Protein uniprotkb Q02784 identity 1529029543069
participant: rpd3_yeast

RelationshipXref intact EBI-7537888 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7537888
db: intact

UnificationXref mint MINT-2208554
type: UnificationXref
id: MINT-2208554
db: mint

ExperimentalForm 8f0b6fda-ae80-46df-aaa4-62a15aed25df
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

rim1-lsp1
type: MolecularInteraction
xref: UnificationXref mint MINT-2198312
xref: RelationshipXref imex IM-15332-806 imex-primary
xref: RelationshipXref intact EBI-7518663 identity
evidence: Evidence dd77696c-7725-4aaa-80e4-3f2d719ff3f8 IM-15332-806 431069 430156
interaction type: physical association
comment: author-confidence:z-score: 5.15373585924731
comment: author-confidence:reliability score: 0.77
comment: comment:mint
data source: intact
participant: rim1_yeast
participant: lsp1_yeast

RelationshipXref rcsb pdb 3HOZ
type: RelationshipXref
id: 3HOZ
db: protein data bank

RelationshipXref rcsb pdb 3HOY
type: RelationshipXref
id: 3HOY
db: protein data bank

RelationshipXref rcsb pdb 3HOX
type: RelationshipXref
id: 3HOX
db: protein data bank

Evidence 3d51e287-deb5-49b1-8e5e-8a3fe8ef8af7 IM-15332-10860 433313 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref imex IM-15332-1217 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1217
db: imex

RelationshipXref rcsb pdb 3HOU
type: RelationshipXref
id: 3HOU
db: protein data bank

RelationshipXref go GO 0000903
type: RelationshipXref
id: GO:0000903
db: gene ontology

ExperimentalForm b7ddec5a-7c8e-43da-b7eb-d7edda1aeb22
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref intact EBI-7520289 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7520289
db: intact

RelationshipXref intact EBI-7534596 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7534596
db: intact

ExperimentalForm d3e31080-717a-430c-abd8-3f009eaa5f7b
type: ExperimentalForm
experimental feature: ModificationFeature 864b22a2-f4bd-4ec8-a890-7d596c319fae 432135
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

rpc82-rpc34
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-12888 imex-primary
xref: UnificationXref mint MINT-2208176
xref: RelationshipXref intact EBI-7537090 identity
evidence: Evidence 42912c41-329b-4408-bf7c-05255bedd7eb IM-15332-12888 433249 430156
interaction type: physical association
comment: author-confidence:z-score: 0.0777698170658264
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P32349 identity 1529029543028
participant: Protein uniprotkb P32910 identity 1529029543029

RelationshipXref interpro IPR012725
type: RelationshipXref
id: IPR012725
db: interpro

ExperimentalForm c2d7764d-0934-426e-b57b-9a0d97606477
type: ExperimentalForm
experimental feature: ModificationFeature 77ea7cab-f2f4-4981-97d6-7be780b831c5 431503
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref rcsb pdb 4QZ0
type: RelationshipXref
id: 4QZ0
db: protein data bank

UnificationXref mint MINT-2208536
type: UnificationXref
id: MINT-2208536
db: mint

prs10_yeast
type: Protein
evidence: Evidence eafaea70-5d0f-4536-bf5a-02f8fd4ced46 p 433716
entity reference: P53549
name: 26S proteasome subunit RPT4
comment: psi-mi participant
data source: intact

RelationshipXref imex IM-15332-12870 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12870
db: imex

Evidence 2f9246e8-a473-4da7-b05d-880466ff24c4 IM-15332-3593 433161 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref go GO 0035066
type: RelationshipXref
id: GO:0035066
db: gene ontology

RelationshipXref go GO 0035064
type: RelationshipXref
id: GO:0035064
db: gene ontology

RelationshipXref go GO 0070202
type: RelationshipXref
id: GO:0070202
db: gene ontology

UnificationXref mint MINT-2207186
type: UnificationXref
id: MINT-2207186
db: mint

Evidence 640e1e33-f44e-4c5c-81dd-4d35e2ee2df4 IM-15332-5598 433321 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref go GO 0036402
type: RelationshipXref
id: GO:0036402
db: gene ontology

ExperimentalForm f35dad52-c285-4883-ab9f-8c0a38bf58a8
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref sgd S000004989
type: RelationshipXref
id: S000004989
db: sgd

rpc40-rpa135-2
type: MolecularInteraction
xref: RelationshipXref intact EBI-7535551 identity
xref: RelationshipXref imex IM-15332-12495 imex-primary
xref: UnificationXref mint MINT-2207330
evidence: Evidence 5f0ced21-4a94-46d8-b8df-0cf97bf090ac IM-15332-12495 433061 430156
interaction type: physical association
comment: author-confidence:z-score: 2.85859315285022
comment: comment:homomint
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P22138 identity 1529029542934
participant: Protein uniprotkb P07703 identity 1529029542935

med14_yeast
type: Protein
evidence: Evidence f3b9ded3-eff5-4ca2-a0e5-e11a6364995b p 430990
entity reference: P19263
name: Mediator of RNA polymerase II transcription subunit 14
comment: psi-mi participant
data source: intact

rpb4_yeast
type: Protein
evidence: Evidence 699c5a95-adf6-4cc5-86a7-9bd241692d2e p 431970
entity reference: P20433
name: DNA-directed RNA polymerase II subunit RPB4
comment: psi-mi participant
data source: intact

UnificationXref mint MINT-2197844
type: UnificationXref
id: MINT-2197844
db: mint

Evidence b438a960-70e8-4ad9-b43a-79395c8c94af IM-15332-8817 432725 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref imex IM-15332-8412 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-8412
db: imex

UnificationXref mint MINT-2200148
type: UnificationXref
id: MINT-2200148
db: mint

UnificationXref mint MINT-2208518
type: UnificationXref
id: MINT-2208518
db: mint

Evidence 51ff9de8-2153-4579-9f85-3f017881a663 IM-15332-8409 430869 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref go GO 0042273
type: RelationshipXref
id: GO:0042273
db: gene ontology

prs7_yeast
type: ProteinReference
sequence: MPPKEDWEKYKAPLEDDDKKPDDDKIVPLTEGDIQVLKSYGAAPYAAKLKQTENDLKDIEARIKEKAGVKESDTGLAPSHLWDIMGDRQRLGEEHPLQVARCTKIIKGNGESDETTTDNNNSGNSNSNSNQQSTDADEDDEDAKYVINLKQIAKFVVGLGERVSPTDIEEGMRVGVDRSKYNIELPLPPRIDPSVTMMTVEEKPDVTYSDVGGCKDQIEKLREVVELPLLSPERFATLGIDPPKGILLYGPPGTGKTLCARAVANRTDATFIRVIGSELVQKYVGEGARMVRELFEMARTKKACIIFFDEIDAVGGARFDDGAGGDNEVQRTMLELITQLDGFDPRGNIKVMFATNRPNTLDPALLRPGRIDRKVEFSLPDLEGRANIFRIHSKSMSVERGIRWELISRLCPNSTGAELRSVCTEAGMFAIRARRKVATEKDFLKAVDKVISGYKKFSSTSRYMQYN
xref: RelationshipXref rcsb pdb 5MPC
xref: RelationshipXref rcsb pdb 5MPB
xref: RelationshipXref rcsb pdb 5MPA
xref: RelationshipXref reactome R-SCE-349425
xref: RelationshipXref rcsb pdb 5MP9
xref: RelationshipXref reactome R-SCE-68949
xref: RelationshipXref rcsb pdb 3JCP
xref: RelationshipXref rcsb pdb 3JCO
xref: RelationshipXref sgd S000001628
xref: RelationshipXref go GO 0045732
xref: RelationshipXref interpro IPR035245
xref: RelationshipXref reactome R-SCE-69601
xref: RelationshipXref rcsb pdb 3VLF
xref: RelationshipXref interpro IPR005937
xref: RelationshipXref interpro IPR003960
xref: RelationshipXref reactome R-SCE-69017
xref: RelationshipXref uniprotkb D6VX51 secondary-ac
xref: RelationshipXref rcsb pdb 4A3V
xref: RelationshipXref interpro IPR003593
xref: RelationshipXref rcsb pdb 5WVI
xref: RelationshipXref go GO 0045899
xref: RelationshipXref reactome R-SCE-8854050
xref: RelationshipXref reactome R-SCE-69229
xref: RelationshipXref interpro IPR003959
xref: RelationshipXref go GO 0031595
xref: RelationshipXref reactome R-SCE-1236978
xref: RelationshipXref reactome R-SCE-5689880
xref: RelationshipXref reactome R-SCE-174113
xref: RelationshipXref dip DIP-2883N
xref: RelationshipXref refseq NP 012777 1
xref: RelationshipXref go GO 0070682
xref: RelationshipXref reactome R-SCE-382556
xref: RelationshipXref interpro IPR027417
xref: RelationshipXref go GO 0006511
xref: RelationshipXref go GO 0030433
xref: RelationshipXref mint P33299
xref: UnificationXref uniprot knowledgebase P33299
xref: RelationshipXref go GO 0005524
xref: RelationshipXref go GO 0031597
xref: RelationshipXref go GO 0017025
xref: RelationshipXref go GO 0008540
xref: RelationshipXref reactome R-SCE-5668541
xref: RelationshipXref rcsb pdb 4CR4
xref: RelationshipXref rcsb pdb 4CR3
xref: RelationshipXref rcsb pdb 4CR2
xref: RelationshipXref reactome R-SCE-450408
xref: RelationshipXref rcsb pdb 5A5B
xref: RelationshipXref rcsb pdb 4JPO
xref: RelationshipXref rcsb pdb 5WVK
xref: RelationshipXref reactome R-SCE-6798695
xref: RelationshipXref reactome R-SCE-983168
xref: RelationshipXref intact EBI-13910 identity
xref: RelationshipXref go GO 0036402
xref: RelationshipXref reactome R-SCE-5687128
xref: RelationshipXref go GO 0016887
organism: http://identifiers.org/taxonomy/559292
name: YTA3
name: CIM5
name: 26S proteasome regulatory subunit 7 homolog
name: Protein CIM5
name: Tat-binding homolog 3
name: RPT1
name: YKL145W

Evidence a330939e-89e1-4613-acbb-cff26d763957 IM-15332-3995 433057 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

UnificationXref mint MINT-2196492
type: UnificationXref
id: MINT-2196492
db: mint

RelationshipXref sgd S000004970
type: RelationshipXref
id: S000004970
db: sgd

UnificationXref mint MINT-2207168
type: UnificationXref
id: MINT-2207168
db: mint

RelationshipXref rcsb pdb 2E2J
type: RelationshipXref
id: 2E2J
db: protein data bank

RelationshipXref rcsb pdb 2E2I
type: RelationshipXref
id: 2E2I
db: protein data bank

RelationshipXref rcsb pdb 2E2H
type: RelationshipXref
id: 2E2H
db: protein data bank

rpc2_yeast
type: Protein
evidence: Evidence 31673f8b-bf95-4028-9f26-aa6b92809948 p 432614
entity reference: P22276
name: DNA-directed RNA polymerase III subunit RPC2
comment: psi-mi participant
data source: intact

ExperimentalForm 3a6beaa4-d789-4e86-842c-b23d35acd9b4
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

RelationshipXref imex IM-15332-3980 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-3980
db: imex

rpc2_yeast
type: Protein
evidence: Evidence 7fa6e212-f261-4cb4-8596-4f23cac97d57 p 432620
entity reference: P22276
name: DNA-directed RNA polymerase III subunit RPC2
comment: psi-mi participant
data source: intact

RelationshipXref interpro IPR011344
type: RelationshipXref
id: IPR011344
db: interpro

UnificationXref mint MINT-2208500
type: UnificationXref
id: MINT-2208500
db: mint

ExperimentalForm 0adecb3e-eb99-48f0-98b1-9c4b641279a4
type: ExperimentalForm
experimental feature: ModificationFeature ba8d724d-12a9-4664-a06f-d487958669f8 430375
comment: [ExperimentalFormVocabulary_bait]
comment: [ModificationFeature: {tap tagged}]
experimental form description: ExperimentalFormVocabulary 701737e5cf53d06134cbd3ee59611827

RelationshipXref imex IM-15332-1950 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-1950
db: imex

RelationshipXref intact EBI-15854 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-15854
db: intact

UnificationXref mint MINT-2197826
type: UnificationXref
id: MINT-2197826
db: mint

UnificationXref mint MINT-2207150
type: UnificationXref
id: MINT-2207150
db: mint

rgr1-cse2-1
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-8802 imex-primary
xref: RelationshipXref intact EBI-7518391 identity
xref: UnificationXref mint MINT-2198078
evidence: Evidence 467d9e20-6184-46f1-8c4a-3f98d3ffc523 IM-15332-8802 431017 430156
interaction type: physical association
comment: author-confidence:z-score: 3.94346720789321
comment: author-confidence:reliability score: 0.921
comment: comment:mint
data source: intact
participant: Protein uniprotkb P19263 identity 1529029541913
participant: med9_yeast

rfc1-rfc3-9
type: MolecularInteraction
xref: UnificationXref mint MINT-2197790
xref: RelationshipXref imex IM-15332-5975 imex-primary
xref: RelationshipXref intact EBI-7518007 identity
evidence: Evidence 10749082-b025-4d59-b053-4e40492bc170 IM-15332-5975 430953 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:reliability score: 0.989
comment: comment:mint
comment: author-confidence:z-score: 2.95807795770218
data source: intact
participant: Protein uniprotkb P38630 identity 1529029541880
participant: Protein uniprotkb P38629 identity 1529029541881

RelationshipXref imex IM-15332-12038 imex-primary
type: RelationshipXref
relationship type: MI:0662
id: IM-15332-12038
db: imex

rpn10_yeast
type: Protein
evidence: Evidence a7a2830f-f2ec-4882-a0f1-c80ebd9f7769 p 433710
entity reference: P38886
name: 26S proteasome regulatory subunit RPN10
comment: psi-mi participant
data source: intact

RelationshipXref interpro IPR006886
type: RelationshipXref
id: IPR006886
db: interpro

RelationshipXref interpro IPR011332
type: RelationshipXref
id: IPR011332
db: interpro

RelationshipXref interpro IPR011331
type: RelationshipXref
id: IPR011331
db: interpro

UnificationXref mint MINT-2200976
type: UnificationXref
id: MINT-2200976
db: mint

UnificationXref mint MINT-2196474
type: UnificationXref
id: MINT-2196474
db: mint

RelationshipXref sgd S000004954
type: RelationshipXref
id: S000004954
db: sgd

ref2-pta1
type: MolecularInteraction
xref: UnificationXref mint MINT-2195501
xref: RelationshipXref intact EBI-7515380 identity
xref: RelationshipXref imex IM-15332-4762 imex-primary
evidence: Evidence b24a0051-5de2-4ae9-b99e-82b4233eb3e6 IM-15332-4762 430445 430156
interaction type: physical association
comment: author-confidence:z-score: 6.63097703224129
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: Protein uniprotkb P42073 identity 1529029541627
participant: Protein uniprotkb Q01329 identity 1529029541626

prs7_yeast
type: Protein
evidence: Evidence 4d97a337-d30e-4772-8835-61ec64b2ee90 p 433888
entity reference: prs7_yeast
name: 26S proteasome regulatory subunit 7 homolog
comment: psi-mi participant
data source: intact

RelationshipXref go GO 0035023
type: RelationshipXref
id: GO:0035023
db: gene ontology

RelationshipXref intact EBI-10517 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-10517
db: intact

RelationshipXref intact EBI-7522697 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-7522697
db: intact

RelationshipXref intact EBI-9190 identity
type: RelationshipXref
relationship type: MI:0356
id: EBI-9190
db: intact

yp225_yeast
type: Protein
evidence: Evidence a134ad10-fbfc-4e2e-911c-31842b18d6df p 432338
entity reference: Q08971
name: Protein PBDC1 homolog
comment: psi-mi participant
data source: intact

yp225_yeast
type: Protein
evidence: Evidence 8331b5b9-ad8a-436f-821d-6206f35147eb p 432346
entity reference: Q08971
name: Protein PBDC1 homolog
comment: psi-mi participant
data source: intact

RelationshipXref reactome R-SCE-6804758
type: RelationshipXref
id: R-SCE-6804758
db: reactome

RelationshipXref reactome R-SCE-6804757
type: RelationshipXref
id: R-SCE-6804757
db: reactome

RelationshipXref sgd S000004949
type: RelationshipXref
id: S000004949
db: sgd

prs7_yeast
type: Protein
evidence: Evidence c76e923c-b1f4-49cb-8016-1441df339a6f p 433868
entity reference: prs7_yeast
name: 26S proteasome regulatory subunit 7 homolog
comment: psi-mi participant
data source: intact

ExperimentalForm 747d3538-74cc-480d-976f-1dae38988477
type: ExperimentalForm
comment: [ExperimentalFormVocabulary_prey]
experimental form description: ExperimentalFormVocabulary 3c522328d903bc61ce3a4f4872566585

UnificationXref mint MINT-2197808
type: UnificationXref
id: MINT-2197808
db: mint

UnificationXref mint MINT-2207132
type: UnificationXref
id: MINT-2207132
db: mint

rpc19-ret1-6
type: MolecularInteraction
xref: RelationshipXref intact EBI-7533798 identity
xref: RelationshipXref imex IM-15332-11256 imex-primary
xref: UnificationXref mint MINT-2206357
evidence: Evidence a87e2423-1eca-4fe7-8ed7-00bfea1c6f59 IM-15332-11256 432845 430156
interaction type: physical association
comment: comment:homomint
comment: author-confidence:z-score: 0.0245261734876861
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: rpac2_yeast
participant: Protein uniprotkb P22276 identity 1529029542826

Evidence b9cd3e10-1c08-4a04-bf14-c10c12b05887 IM-15332-819 433793 430156
type: Evidence
xref: RelationshipXref doi 10 1038 nature04670 secondary-ac
xref: http://identifiers.org/pubmed/16554755
xref: RelationshipXref mint MINT-5218454 primary-reference
xref: RelationshipXref imex IM-15332 imex-primary
xref: UnificationXref mint MINT-1978243
xref: RelationshipXref intact EBI-6933345 identity
comment: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
comment: The authors generated a large dataset of interactions using the tandem affinity purification technology (TAP). The prey proteins were identified in parallel experiments by MALDI-TOF/MS and LC-MS/MS analysis. A core dataset of binary interaction was generated by a machine learning procedure assigning a confidence score to each interactions. All the interactions belonging to the core dataset display a confidence score higher than 0.273. In MINT are collected only the interactions belonging to the core dataset. For each interaction the confidence score is reported. For each protein identified by MALDI-TOF/MS the numbers of peptides detected are reported; the Z-score provides confidence measure for the identification of the protein. For each protein identified by LC-MS/MS numbers of peptides detected are reported; the probability value provides confidence measure for the identification of the protein. All the original datasets provided by the authors are available at the following URL : ftp://mint.bio.uniroma2.it/pub/data/krogan-2006 comment MI:0612
comment: 2006 publication year MI:0886
comment: imex curation MI:0959
comment: Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF author-list MI:0636
comment: Host Organism{names=Names{shortLabel='baker's yeast-4l', fullName='Saccharomyces cerevisiae', aliases=null}, cellType=OpenCvType{attributes=null}, compartment=null, tissue=null, ncbiTaxId=4932}
comment: Nature (0028-0836) journal MI:0885
comment: krogan-2006-1
comment: imex curation curation depth MI:0955
comment: Virus - Publications including interactions involving viral proteins dataset MI:0875
comment: Only protein-protein interactions full coverage MI:0957
comment: imex-exported
evidence code: EvidenceCodeVocabulary 07c0a2bf36b72c21a326d39081c7c59b
evidence code: EvidenceCodeVocabulary 9370ec56aed6c17782b99f75ed3e7c94

RelationshipXref refseq NP 011378 1
type: RelationshipXref
id: NP_011378.1
db: refseq

rpc17-ret1-2
type: MolecularInteraction
xref: RelationshipXref imex IM-15332-2360 imex-primary
xref: UnificationXref mint MINT-2205331
xref: RelationshipXref intact EBI-7531796 identity
evidence: Evidence bd11293b-8245-4f9d-a1b3-c84b20b0ad64 IM-15332-2360 432617 430156
interaction type: physical association
comment: author-confidence:z-score: 0.360338431455016
comment: comment:mint
comment: author-confidence:reliability score: 0.99
data source: intact
participant: rpc2_yeast
participant: rpc9_yeast